TWI800773B - 主動矩陣介質電潤濕（ＡＭ - ＥＷｏＤ）數位流體裝置及使用彼以測定分析物之方法 - Google Patents

主動矩陣介質電潤濕（ＡＭ - ＥＷｏＤ）數位流體裝置及使用彼以測定分析物之方法 Download PDF

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Publication number
TWI800773B
TWI800773B TW109142831A TW109142831A TWI800773B TW I800773 B TWI800773 B TW I800773B TW 109142831 A TW109142831 A TW 109142831A TW 109142831 A TW109142831 A TW 109142831A TW I800773 B TWI800773 B TW I800773B
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Taiwan
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ewod
assaying
analyte
dielectric
same
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TW109142831A
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TW202135941A (zh
Inventor
大衛 辛湯摩斯基
理查Ｊ 小波里尼
伊恩 法蘭奇
提摩西Ｊ 歐馬利
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英商核酸有限公司
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/023—Adapting objects or devices to another adapted for different sizes of tubes, tips or container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
TW109142831A 2019-12-04 2020-12-04 主動矩陣介質電潤濕（ＡＭ - ＥＷｏＤ）數位流體裝置及使用彼以測定分析物之方法 TWI800773B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962943295P 2019-12-04 2019-12-04
US62/943,295 2019-12-04

Publications (2)

Publication Number Publication Date
TW202135941A TW202135941A (zh) 2021-10-01
TWI800773B true TWI800773B (zh) 2023-05-01

Family

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Family Applications (1)

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TW109142831A TWI800773B (zh) 2019-12-04 2020-12-04 主動矩陣介質電潤濕（ＡＭ - ＥＷｏＤ）數位流體裝置及使用彼以測定分析物之方法

Country Status (7)

Country Link
US (1) US20210170413A1 (zh)
EP (1) EP4069425A4 (zh)
JP (1) JP2023504518A (zh)
KR (1) KR20220110517A (zh)
CN (1) CN114746183A (zh)
TW (1) TWI800773B (zh)
WO (1) WO2021113485A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11727957B1 (en) 2022-06-10 2023-08-15 Seagate Technology Llc Data storage drive with a vertically translatable actuator arm
TWI806764B (zh) * 2022-09-12 2023-06-21 友達光電股份有限公司 介電潤濕裝置

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI303714B (en) * 2004-10-14 2008-12-01 Toshiba Kk Nucleic acid detecting sensor, nucleic acid detecting chip, and nucleic acid detecting circuit
CN101651093A (zh) * 2007-08-15 2010-02-17 索尼株式会社 半导体薄膜形成方法和半导体薄膜检查装置
WO2014036915A1 (en) * 2012-09-04 2014-03-13 Shanghai Hengxin Biological Technology Co.,Ltd Dielectrophoresis based apparatuses and methods for the manipulation of particles in liquids
TW201629480A (zh) * 2014-12-18 2016-08-16 生命技術公司 用於使用大規模fet陣列量測分析物之方法及設備
JP2018051685A (ja) * 2016-09-28 2018-04-05 シャープ ライフ サイエンス （イーユー） リミテッド 微小流体装置
US20190111433A1 (en) * 2017-10-18 2019-04-18 E Ink Corporation Digital microfluidic devices including dual substrates with thin-film transistors and capacitive sensing

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100120130A1 (en) * 2007-08-08 2010-05-13 Advanced Liquid Logic, Inc. Droplet Actuator with Droplet Retention Structures
CN102671724B (zh) * 2011-02-17 2015-03-11 王崇智 微电极阵列结构
US9254485B2 (en) * 2012-12-17 2016-02-09 Taiwan Semiconductor Manufacturing Company, Ltd. Systems and methods for an integrated bio-entity manipulation and processing device
US10369570B2 (en) * 2017-07-27 2019-08-06 Sharp Life Science (Eu) Limited Microfluidic device with droplet pre-charge on input
CN107497509B (zh) * 2017-10-11 2020-05-26 京东方科技集团股份有限公司 微流控系统及其驱动方法
CN108855266B (zh) * 2018-07-23 2020-07-28 京东方科技集团股份有限公司 液滴移动装置、微流控系统及其工作方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI303714B (en) * 2004-10-14 2008-12-01 Toshiba Kk Nucleic acid detecting sensor, nucleic acid detecting chip, and nucleic acid detecting circuit
CN101651093A (zh) * 2007-08-15 2010-02-17 索尼株式会社 半导体薄膜形成方法和半导体薄膜检查装置
WO2014036915A1 (en) * 2012-09-04 2014-03-13 Shanghai Hengxin Biological Technology Co.,Ltd Dielectrophoresis based apparatuses and methods for the manipulation of particles in liquids
TW201629480A (zh) * 2014-12-18 2016-08-16 生命技術公司 用於使用大規模fet陣列量測分析物之方法及設備
JP2018051685A (ja) * 2016-09-28 2018-04-05 シャープ ライフ サイエンス （イーユー） リミテッド 微小流体装置
US20190111433A1 (en) * 2017-10-18 2019-04-18 E Ink Corporation Digital microfluidic devices including dual substrates with thin-film transistors and capacitive sensing

Also Published As

Publication number Publication date
JP2023504518A (ja) 2023-02-03
WO2021113485A1 (en) 2021-06-10
TW202135941A (zh) 2021-10-01
EP4069425A4 (en) 2023-11-08
KR20220110517A (ko) 2022-08-08
CN114746183A (zh) 2022-07-12
US20210170413A1 (en) 2021-06-10
EP4069425A1 (en) 2022-10-12

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