TWI788065B - Bone cutting and repairing-aided sysyem, method and computer program product thereof - Google Patents

Bone cutting and repairing-aided sysyem, method and computer program product thereof Download PDF

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TWI788065B
TWI788065B TW110139320A TW110139320A TWI788065B TW I788065 B TWI788065 B TW I788065B TW 110139320 A TW110139320 A TW 110139320A TW 110139320 A TW110139320 A TW 110139320A TW I788065 B TWI788065 B TW I788065B
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guide plate
bone cutting
repairing
edge
inner edge
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TW110139320A
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TW202317043A (en
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吳杰才
詹淳勝
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長庚醫療財團法人林口長庚紀念醫院
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A bone cutting and repairing-aided system is provided. The bone cutting-aided system includes: a lesion range formation module, a cutting guide generating module and a repairing mould generation module. The lesion range formation module forms a lesion range on a 3D image according a HU value of each area on the 3D image. The cutting guide generating module extends the lesion range to determine an inner diameter and an outer diameter of a cutting guide. Wherein, the cutting guide generating module further maps an inner surface of the cutting guide on the 3D image according to the inner diameter and the outer diameter of the cutting guide, and extends a thickness from the inner surface of the cutting guide, so as to generate a model of the cutting guide. The repairing mould generation module maps an outer surface of a repairing mould with the same curvature as a bone cutting part on the 3D image according to the lesion range and the inner diameter of the cutting guide., and extends a thickness from the outer surface of the repairing mould for forming a three dimensional object, so as to generate a model of the repairing mould.

Description

骨頭切割修補輔助系統、方法及電腦程式產品 Bone cutting and repair assisting system, method and computer program product

本發明關聯於電腦輔助技術,特別是骨頭切割及修補相關的電腦輔助技術。 The present invention is related to computer-aided technology, especially the computer-aided technology related to bone cutting and repair.

目前的骨頭切割及修復手術大部分仰賴執刀醫師的經驗,醫師根據自身視覺判斷,對患者的患部進行切除,並於切除完成後再進行骨頭修補。然而,骨頭切割及修補的效果會隨著不同執刀醫師而不同,手術的精確度難以維持。此外,骨頭的修補塊亦是由醫師以手做的方式塑形,較難以與切割部位完全吻合,可能會造成患者不便。 Most of the current bone cutting and repair operations rely on the experience of the surgeon who performs the surgery. The doctor resects the patient's affected part according to his own visual judgment, and then performs bone repair after the resection is completed. However, the results of bone cutting and repair will vary with different surgeons, and it is difficult to maintain the accuracy of the operation. In addition, the bone repair block is also shaped by the doctor by hand, and it is difficult to completely match the cut site, which may cause inconvenience to the patient.

有鑑於此,本發明提供一種骨頭切割修補輔助系統、方法及電腦程式產品,來解決上述的問題。 In view of this, the present invention provides a bone cutting and repairing auxiliary system, method and computer program product to solve the above problems.

本發明的一目的是提供一種骨頭切割修補輔助系統。骨頭切割修補輔助系統包含:一病灶範圍取得模組及一導引板生成模組。病灶範圍取得模組用於根據一三維影像上各區域的醫學相關數值,在三維影像上取得一病灶範 圍;導引板生成模組用於將病灶範圍向外圍擴展,以取得一導引板內緣及一導引板外緣。其中,導引板生成模組更用於根據導引板內緣及導引板外緣,在三維影像上映射出一導引板內表面,以及自導引板內表面延伸出一導引板厚度,以生成一導引板模板。 One object of the present invention is to provide an auxiliary system for bone cutting and repairing. The bone cutting and repairing auxiliary system includes: a lesion range obtaining module and a guide plate generating module. The lesion range obtaining module is used to obtain a lesion range on a three-dimensional image according to the medically relevant values of each area on a three-dimensional image. perimeter; the guide plate generation module is used to expand the range of the lesion to the periphery, so as to obtain an inner edge of the guide plate and an outer edge of the guide plate. Among them, the guide plate generation module is further used to map an inner surface of the guide plate on the three-dimensional image according to the inner edge of the guide plate and the outer edge of the guide plate, and extend a thickness of the guide plate from the inner surface of the guide plate , to generate a guide plate template.

在一些實施例中,骨頭切割修補輔助系統更包含一填補物模板生成模組。填補物模板生成模組用於根據導引板內緣,在三維影像上取得一填補物外表面,並自填補物外表面延伸出一填補物厚度,以生成一填補物模板。 In some embodiments, the bone cutting and repair assisting system further includes a filling template generating module. The filler template generation module is used to obtain a filler outer surface on the three-dimensional image according to the inner edge of the guide plate, and extend a filler thickness from the filler outer surface to generate a filler template.

又,在一些實施例中,導引板生成模組是依照一第一預設值將病灶範圍向外擴展,以取得導引板內緣,其中第一預設值介於0.5至10微米之間。 Moreover, in some embodiments, the guide plate generation module expands the lesion area outward according to a first preset value to obtain the inner edge of the guide plate, wherein the first preset value is between 0.5 and 10 microns between.

又,在一些實施例中,導引板生成模組是依照一第二預設值將導引板內緣向外擴展,以取得導引板外緣,其中第二預設值介於1至5微米之間。 Furthermore, in some embodiments, the guide plate generation module expands the inner edge of the guide plate outwards according to a second preset value to obtain the outer edge of the guide plate, wherein the second preset value is between 1 and between 5 microns.

又,在一些實施例中,骨頭切割修補輔助系統更包含一邊緣優化模組,用於對導引板內緣執行一邊緣平滑化運算,以優化導引板內緣。 Moreover, in some embodiments, the bone cutting and repairing assisting system further includes an edge optimization module for performing an edge smoothing operation on the inner edge of the guide plate to optimize the inner edge of the guide plate.

本發明的另一目的是提供一種骨頭切割修補輔助方法,由一骨頭切割修補輔助系統執行。該方法包含步驟:根據一三維影像上各區域的醫學相關數值,在三維影像上取得一病灶範圍;將病灶範圍向外圍擴展,以取得一導引板內緣及一導引板外緣;以及根據導引板內緣及導引板外緣,在三維影像上映射出一導引板內表面,以及自導引板內表面延伸出一導引板厚度,以生成一導引板模板。 Another object of the present invention is to provide a method for assisting bone cutting and repair, which is performed by a bone cutting and repair assisting system. The method comprises the steps of: obtaining a lesion range on the three-dimensional image according to the medically relevant values of each area on the three-dimensional image; expanding the lesion range to the periphery to obtain an inner edge of a guide plate and an outer edge of a guide plate; and According to the inner edge of the guide plate and the outer edge of the guide plate, an inner surface of the guide plate is mapped on the three-dimensional image, and a thickness of the guide plate is extended from the inner surface of the guide plate to generate a template of the guide plate.

在一些實施例中,骨頭切割修補輔助方法更包含步驟:根據導引板內緣,在三維影像上取得一填補物外表面,並自填補物外表面延伸出一填補物厚度,以生成一填補物模板。 In some embodiments, the bone cutting and repairing auxiliary method further includes the steps of: obtaining an outer surface of the filling on the three-dimensional image according to the inner edge of the guide plate, and extending a thickness of the filling from the outer surface of the filling to generate a filling object template.

又,在一些實施例中,導引板內緣是依照一第一預設值將病灶範圍向外擴展而取得,其中第一預設值介於0.5至10微米之間;導引板外緣是依照一第二預設值將病灶範圍向外擴展而取得,其中第二預設值介於1至5微米之間。 Moreover, in some embodiments, the inner edge of the guide plate is obtained by expanding the range of the lesion outward according to a first preset value, wherein the first preset value is between 0.5 and 10 microns; the outer edge of the guide plate It is obtained by expanding the range of the lesion outward according to a second preset value, wherein the second preset value is between 1 and 5 microns.

又,在一些實施例中,骨頭切割修補輔助方法更包含步驟:對導引板內緣執行一邊緣平滑化運算,以優化導引板內緣。 Moreover, in some embodiments, the bone cutting and repairing auxiliary method further includes a step of: performing an edge smoothing operation on the inner edge of the guide plate to optimize the inner edge of the guide plate.

本發明又另一目的是提供一種電腦程式產品,儲存於一非暫態電腦可讀取媒介中,用於使一骨頭切割修補輔助系統執行特定程序。電腦程式產品包含:一指令,使骨頭切割修補輔助系統根據一三維影像上各區域的醫學相關數值,在三維影像上取得一病灶範圍;一指令,使骨頭切割修補輔助系統將病灶範圍向外圍擴展,以取得一導引板內緣及一導引板外緣;一指令,使骨頭切割修補輔助系統根據導引板內緣及導引板外緣,在三維影像上映射出一導引板內表面,以及自導引板內表面延伸出一導引板厚度,以生成一導引板模板。 Yet another object of the present invention is to provide a computer program product stored in a non-transitory computer readable medium for enabling a bone cutting and repairing assisting system to execute a specific program. The computer program product includes: an instruction to make the bone cutting and repairing auxiliary system obtain a lesion range on the three-dimensional image according to the medically relevant values of each area on the three-dimensional image; an instruction to make the bone cutting and repairing auxiliary system expand the lesion range to the periphery , to obtain an inner edge of the guide plate and an outer edge of the guide plate; an instruction to make the bone cutting and repair auxiliary system map an inner surface of the guide plate on the three-dimensional image according to the inner edge of the guide plate and the outer edge of the guide plate , and a guide plate thickness is extended from the inner surface of the guide plate to generate a guide plate template.

1:骨頭切割修補輔助系統 1: Bone cutting and repairing auxiliary system

2:處理裝置 2: Processing device

3:醫學影像取得裝置 3: Medical image acquisition device

4:三維影像重組模組 4: 3D image reconstruction module

5:病灶範圍取得模組 5: Lesion range acquisition module

6:導引板生成模組 6: Guide plate generation module

7:邊緣優化模組 7: Edge optimization module

8:填補物生成模組 8: Filling generation module

9:模具製造機台 9:Mold making machine

10:導引板模板 10: Guide plate template

11:填補物模板 11: Filler template

20:微處理器 20: Microprocessor

21:電腦程式產品 21:Computer program products

100:導引板 100: guide plate

110:填補物 110: filler

F1:三維影像 F1: 3D image

C1:病灶範圍 C1: the extent of the lesion

r1:導引板內緣 r1: inner edge of guide plate

r2:導引板外緣 r2: Outer edge of guide plate

s1:導引板內表面 s1: Inner surface of guide plate

t1:導引板厚度 t1: guide plate thickness

s2:填補物外表面 s2: The outer surface of the filling

t2:填補物厚度 t2: Filling thickness

圖1是本發明一實施例的骨頭切割修補輔助系統的系統架構圖;圖2是本發明一實施例的導引板的示意圖;圖3是本發明一實施例的填補物的示意圖;圖4是本發明一實施例的骨頭切割修補輔助方法的步驟流程圖。 Fig. 1 is a system architecture diagram of a bone cutting and repairing auxiliary system according to an embodiment of the present invention; Fig. 2 is a schematic diagram of a guide plate according to an embodiment of the present invention; Fig. 3 is a schematic diagram of a filler according to an embodiment of the present invention; Fig. 4 It is a flow chart of the steps of the bone cutting and repairing auxiliary method according to an embodiment of the present invention.

圖5是圖4實施例的步驟S12至S17所對應的示意圖。 FIG. 5 is a schematic diagram corresponding to steps S12 to S17 of the embodiment in FIG. 4 .

圖6是圖4實施例的步驟S21至S23所對應的示意圖。 FIG. 6 is a schematic diagram corresponding to steps S21 to S23 of the embodiment in FIG. 4 .

以下係藉由特定的具體實施例說明本發明之實施方式。本發明亦可藉由其他不同的具體實施例加以施行或應用,本說明書中的各項細節亦可針對不同觀點與應用,在不悖離本發明之精神下進行各種修飾與變更。 The implementation of the present invention is described below through specific examples. The present invention can also be implemented or applied through other different specific embodiments, and various modifications and changes can be made to the details in this specification for different viewpoints and applications without departing from the spirit of the present invention.

再者,說明書與請求項中所使用的序數例如“第一”、“第二”等之用詞,以修飾請求項之元件,其本身並不意含及代表該請求元件有任何之前的序數,也不代表某一請求元件與另一請求元件的順序、或是製造方法上的順序,該些序數的使用僅用來使具有某命名的一請求元件得以和另一具有相同命名的請求元件能作出清楚區分。 Furthermore, the ordinal numbers used in the description and claims, such as "first", "second", etc., are used to modify the elements of the claims, which do not imply and represent that the claimed elements have any previous ordinal numbers, Nor does it represent the order of a requested element with another claimed element, or the order of the manufacturing method, and the use of these ordinal numbers is only used to enable a claimed element with a certain designation to be able to be used with another claimed element with the same designation. Make a clear distinction.

本文中關於“當...”或“...時”等描述表示”當下、之前或之後”等態樣,而不限定為同時發生之情形,在此先行敘明。此外,本文中記載多個功效時,若在功效之間使用“或”一詞,係表示功效可獨立存在,但不排除多個功效可同時存在。再者,本發明記載一元件進行特殊運作時,是表示該元件不僅能夠執行該特殊運作,且亦可執行其它運作。 In this article, the descriptions of "when..." or "...when" mean "now, before or after" and other aspects, and are not limited to situations that occur at the same time, which is described first here. In addition, when multiple functions are described herein, if the word "or" is used between the functions, it means that the functions can exist independently, but it does not exclude that multiple functions can exist at the same time. Furthermore, when the present invention states that a component performs a special operation, it means that the component can not only perform the special operation, but also perform other operations.

請同時參考圖1至圖3。圖1是本發明一實施例的骨頭切割修補輔助系統1的系統架構圖,圖2是本揭露一實施例的導引板100的示意圖,而圖3是本揭露一實施例的填補物110的示意圖。 Please refer to Figure 1 to Figure 3 at the same time. FIG. 1 is a system architecture diagram of a bone cutting and repair assisting system 1 according to an embodiment of the present invention, FIG. 2 is a schematic diagram of a guide plate 100 according to an embodiment of the disclosure, and FIG. 3 is a schematic diagram of a filler 110 according to an embodiment of the disclosure. schematic diagram.

如圖1所示,骨頭切割修補輔助系統1可包含一處理裝置2及一醫學影像取得裝置3。處理裝置2可包含一三維影像重組模組4、一病灶範圍取得模組5及一導引板生成模組6。此外,在一些實施例中,處理裝置2可更包含一邊緣優化模組7及一填補物生成模組8。另外,在一些實施例中,骨頭切割修補輔助系統1可更包含一模具製造機台9,且不限於此。 As shown in FIG. 1 , the bone cutting and repair assisting system 1 may include a processing device 2 and a medical image obtaining device 3 . The processing device 2 may include a three-dimensional image reconstruction module 4 , a lesion range acquisition module 5 and a guide plate generation module 6 . In addition, in some embodiments, the processing device 2 may further include an edge optimization module 7 and a filler generation module 8 . In addition, in some embodiments, the bone cutting and repair assisting system 1 may further include a mold making machine 9 , and is not limited thereto.

如圖1至圖3所示,醫學影像取得裝置3可用於取得複數個醫學影像。三維影像重建模組4可用於將該等醫學影像重建成一三維影像(可另參考圖5之三維影像F1)。病灶範圍取得模組5可用於在三維影像上取得一病灶範圍(可另參考圖5之病灶範圍C1)。導引板生成模組6可用於根據病灶範圍生成一導引板模板10。填補物生成模組8可根據病灶範圍生成一填補物模板11。模具製造機台9可根據導引板模板10製造出實際的一導引板100。此外,骨頭切割修補輔助系統1亦可用於生成一填補物模板11,而模具製造機台9可根據填補物模板11製造出實際的一填補物110。 As shown in FIGS. 1 to 3 , the medical image acquisition device 3 can be used to acquire a plurality of medical images. The 3D image reconstruction unit 4 can be used to reconstruct the medical images into a 3D image (please also refer to the 3D image F1 in FIG. 5 ). The lesion area acquisition module 5 can be used to acquire a lesion area on the 3D image (please also refer to the lesion area C1 in FIG. 5 ). The guide plate generation module 6 can be used to generate a guide plate template 10 according to the scope of the lesion. The filling generation module 8 can generate a filling template 11 according to the scope of the lesion. The mold manufacturing machine 9 can manufacture an actual guide plate 100 according to the guide plate template 10 . In addition, the bone cutting and repairing auxiliary system 1 can also be used to generate a filling template 11 , and the mold making machine 9 can manufacture an actual filling 110 according to the filling template 11 .

又如圖2所示,導引板100可例如是一環狀立體結構,其具有一導引板內緣r1及一導引板外緣r2,而導引板內緣r1與導引板外緣r2之間可具有一導引板內表面s1。此外,導引板100可對應骨頭的欲切除部位的形狀,因此使用者(例如醫師)可將導引板100放置於欲切除部位處,藉此進行定位。此外,導引板100的導引板內緣r1可對應欲切除的範圍,因此當導引板100放置完成後,醫師即可沿著導引板內緣r1切除欲切除部位。藉此,切除過程可不再仰賴醫師的眼力,對於切割的精準度將可提升。 Also as shown in Figure 2, the guide plate 100 can be, for example, a ring-shaped three-dimensional structure, which has a guide plate inner edge r1 and a guide plate outer edge r2, and the guide plate inner edge r1 and the guide plate outer edge r1 There may be an inner surface s1 of a guide plate between the edges r2. In addition, the guide plate 100 can correspond to the shape of the part of the bone to be resected, so the user (such as a doctor) can place the guide plate 100 at the part to be resected, so as to perform positioning. In addition, the inner edge r1 of the guide plate 100 can correspond to the area to be resected, so after the guide plate 100 is placed, the doctor can cut the area to be resected along the inner edge r1 of the guide plate. In this way, the resection process no longer depends on the doctor's eyesight, and the accuracy of the cut can be improved.

在一些實施例中,導引板100的材質可例如是醫療級材料,例如必須保持無菌的狀態、可用於醫療作業或可植入於人體等。在一些實施例中,導引板100的材質具備生物相容性,例如符合醫療器材法規之生物相容性規範ISO 10993的材質,但不限於此。在一些實施例中,導引板100的材質具備生物不可分解性(nonbiodegradable),例如可包含聚甲基丙烯酸甲酯類、聚乙烯類、矽膠類、聚酯類、鈷合金類、鈦合金類、耐龍類、聚苯乙烯類、聚丙烯類、乙烯類樹脂類、丙烯腈-丁二烯-苯乙烯共聚物類、碳素類、或該等的任意組合,且不限 於此。在另一些實施例中,導引板100的材質亦可具備生物可分解性(biodegradable)。 In some embodiments, the material of the guide plate 100 may be, for example, a medical grade material, for example, it must be kept in a sterile state, it can be used for medical operations, or it can be implanted in the human body. In some embodiments, the material of the guide plate 100 has biocompatibility, such as the material conforming to the biocompatibility specification ISO 10993 of the medical device regulations, but not limited thereto. In some embodiments, the material of the guide plate 100 is nonbiodegradable, such as polymethyl methacrylate, polyethylene, silicone, polyester, cobalt alloy, titanium alloy. , nylon, polystyrene, polypropylene, vinyl resin, acrylonitrile-butadiene-styrene copolymer, carbon, or any combination thereof, without limitation here. In other embodiments, the material of the guide plate 100 may also be biodegradable.

圖2及圖3所示,填補物110是一立體結構,並具有一填補物外表面s2(標示於圖6)。填補物110可對應導引板100的導引板內緣r1的形狀及大小,因此填補物110可放入導引板內緣r1之中,並且填補物110的外圍將可與導引板內緣r1吻合,但不限於此。因此,當切割手術完成後,醫師即可將填補物110放入骨頭上的切除部位。在一實施例中,填補物外表面s2具有與缺損的頭骨表面一致的弧度。藉此,填補物110的形狀是對應切除部位的形狀而生成,可解決目前手術之填補塊與切除部位無法吻合的問題。 As shown in FIG. 2 and FIG. 3 , the filler 110 is a three-dimensional structure and has an outer surface s2 of the filler (marked in FIG. 6 ). The filler 110 can correspond to the shape and size of the inner edge r1 of the guide plate 100, so the filler 110 can be put into the inner edge r1 of the guide plate, and the periphery of the filler 110 will be compatible with the inner edge r1 of the guide plate. Edge r1 coincides, but is not limited to this. Therefore, after the cutting operation is completed, the doctor can put the filler 110 into the resected part of the bone. In one embodiment, the outer surface s2 of the filling has a curvature consistent with the surface of the defective skull. In this way, the shape of the filling 110 is generated corresponding to the shape of the resection site, which can solve the problem that the current surgical filling block cannot match the resection site.

在一些實施例中,填補物110的材質可採用與導引板100相同的材質,但須注意的是,填補物110的材質必須具備生物不可分解性。 In some embodiments, the material of the filler 110 can be the same as that of the guide plate 100 , but it should be noted that the material of the filler 110 must be biodegradable.

在一實施例中,藉由導引板生成模組6及填補物生成模組8的運作,病患的切割及修補手術可接續進行,亦即切割及修補可在同一次手術中完成。目前現有技術下,必須在切割手術完成後的數個月後才能再進行填補的手術,因此本發明可大幅改善減少時間成本。 In one embodiment, through the operation of the guide plate generating module 6 and the filler generating module 8 , the patients' cutting and repairing operations can be performed consecutively, that is, cutting and repairing can be completed in the same operation. Under the current existing technology, the filling operation must be performed several months after the cutting operation is completed, so the present invention can greatly improve and reduce the time cost.

接著將說明骨頭切割修補輔助系統1中各元件的細節,請再次參考圖1。 Next, the details of each element in the bone cutting and repair assisting system 1 will be explained, please refer to FIG. 1 again.

在一些實施例中,處理裝置2可例如是各種具有微處理器20的電子裝置,例如桌上型電腦、筆記型電腦、智慧型行動裝置、伺服器或雲端主機等,且不限於此。在一些實施例中,處理裝置2可具備網路通訊功能,以將資料透過網路進行傳輸,其中網路通訊可以是有線網路或無線網路,因此處理裝置2亦可透過網路來取得資料,但不限於此。在一些實施例中,處理裝置2中的各功 能模組可由微處理器20執行至少一電腦程式產品21來實現,例如電腦程式產品21可具有複數個指令,該等指令可使微處理器20執行特殊運作,進而使微處理器20可執行三維影像重組模組4、病灶範圍取得模組5、導引板生成模組6、邊緣優化模組7或填補物生成模組8的功能,且不限於此。在一些實施例中,電腦程式產品21可儲存於一非暫態電腦可讀取媒體之中,例如處理裝置2的一記憶體或儲存器(圖未顯示)之中,但不限於此。此外,電腦程式產品21並不限定為在電腦上執行的程式,只要係電子裝置所能夠使用的程式,例如智慧型手機上的程式(application,APP),都屬於本發明的態樣。 In some embodiments, the processing device 2 may be, for example, various electronic devices having a microprocessor 20 , such as a desktop computer, a notebook computer, a smart mobile device, a server or a cloud host, etc., and is not limited thereto. In some embodiments, the processing device 2 can have a network communication function to transmit data through the network, wherein the network communication can be a wired network or a wireless network, so the processing device 2 can also obtain data through the network. information, but not limited to. In some embodiments, each function in the processing device 2 The function module can be implemented by the microprocessor 20 executing at least one computer program product 21, for example, the computer program product 21 can have a plurality of instructions, and these instructions can make the microprocessor 20 perform special operations, and then make the microprocessor 20 executable The functions of the 3D image reconstruction module 4 , the lesion range acquisition module 5 , the guide plate generation module 6 , the edge optimization module 7 or the filler generation module 8 are not limited thereto. In some embodiments, the computer program product 21 may be stored in a non-transitory computer-readable medium, such as a memory or storage (not shown) of the processing device 2 , but is not limited thereto. In addition, the computer program product 21 is not limited to a program executed on a computer, as long as it is a program that can be used by an electronic device, such as a program (application, APP) on a smart phone, it is an aspect of the present invention.

在一些實施例中,醫學影像取得裝置3可例如是各種醫學掃描設備,用於從患者身上取得醫學影像。醫學影像可以是各種醫療相關影像,並包括複數個像素,例如正子斷層造影影像(positron emission tomography,PET影像)、電腦斷層攝影影像(computed tomography,CT影像)、單光子電腦斷層掃描影像(single photon emission tomography,SPECT影像)、超音波影像與磁振造影影像等,且不限於此。醫學影像可以係二維影像或三維影像,在三維影像的情況下,則像素係定義為立體像素,且每個像素對應一醫學相關數值,例如PET影像中的標準代謝(standardized uptake value,SUV)值或是CT影像中的亨式單位(Hounsfield unit,HU)值...等,且不限於此。為方便說明,下文中將皆以醫學影像取得裝置3為電腦斷層攝影裝置,而醫學影像為CT影像,且醫學相關數值為HU值的態樣來舉例說明。 In some embodiments, the medical image obtaining device 3 may be, for example, various medical scanning equipments for obtaining medical images from patients. Medical images can be various medical-related images, and include a plurality of pixels, such as positron emission tomography (PET images), computer tomography (computed tomography, CT images), single photon computer tomography (single photon tomography) images. emission tomography, SPECT image), ultrasound image and magnetic resonance imaging image, etc., but not limited thereto. Medical images can be two-dimensional images or three-dimensional images. In the case of three-dimensional images, pixels are defined as voxels, and each pixel corresponds to a medically relevant value, such as the standardized uptake value (SUV) in PET images. value or a Hounsfield unit (HU) value in a CT image, etc., but not limited thereto. For the convenience of description, the medical image acquiring device 3 is a computerized tomography device, the medical images are CT images, and the medical related values are HU values for example.

在一些實施例裡,三維影像重組模組4、病灶範圍取得模組5、導引板生成模組6、邊緣優化模組7及填補物生成模組8可例如是微處理器20載入電腦程式產品21後所產生的功能模組。在一些實施例裡,三維影像重組模組4、病 灶範圍取得模組5、導引板生成模組6、邊緣優化模組7及填補物生成模組8可以是電腦程式產品21的多個子程式,且不限於此。在一些實施例中,三維影像重組模組4、病灶範圍取得模組5、導引板生成模組6、邊緣優化模組7及填補物生成模組8。 In some embodiments, the three-dimensional image reconstruction module 4, the lesion range acquisition module 5, the guide plate generation module 6, the edge optimization module 7, and the filler generation module 8 can be loaded into a computer, such as a microprocessor 20 The function module generated after the program product 21. In some embodiments, the three-dimensional image reconstruction module 4, disease The range acquisition module 5 , the guide plate generation module 6 , the edge optimization module 7 and the filler generation module 8 may be multiple subroutines of the computer program product 21 , and are not limited thereto. In some embodiments, the 3D image reconstruction module 4 , the lesion range acquisition module 5 , the guide plate generation module 6 , the edge optimization module 7 and the filler generation module 8 .

在一些實施例中,模具製造機台9可例如是3D列印機台,而導引板模板10及填補物模板11可以是3D列印機台所適用的圖檔或檔案,例如但不限於STL檔,並可具備各種列印參數,但不限於此。此外,在另一些實施例中,模具製造機台9亦可以是其它類型的開模設備。 In some embodiments, the mold manufacturing machine 9 may be, for example, a 3D printing machine, and the guide plate template 10 and the filler template 11 may be drawings or files suitable for the 3D printing machine, such as but not limited to STL file, and can have various printing parameters, but not limited thereto. In addition, in other embodiments, the mold manufacturing machine 9 may also be other types of mold opening equipment.

藉此,骨頭切割修補輔助系統1的結構已可被理解。 In this way, the structure of the bone cutting and repair assisting system 1 can be understood.

接著說明骨頭切割修補輔助系統1自動生成導引板模塊10的運作過程。圖4是本發明一實施例的骨頭切割修補輔助方法的步驟流程圖,圖5是圖4實施例中步驟S12至S17所對應的示意圖,並請同時參考圖1至圖3。其中,骨頭切割修補輔助方法是透過骨頭切割修補輔助系統1來執行。 Next, the operation process of the bone cutting and repair assisting system 1 automatically generating the guide plate module 10 will be described. FIG. 4 is a flow chart of the steps of an auxiliary method for bone cutting and repair according to an embodiment of the present invention, and FIG. 5 is a schematic diagram corresponding to steps S12 to S17 in the embodiment of FIG. 4 , and please refer to FIGS. 1 to 3 at the same time. Wherein, the bone cutting and repairing auxiliary method is implemented through the bone cutting and repairing auxiliary system 1 .

如圖4及圖5所示,首先步驟S11被執行,醫學影像取得裝置3取得患者的待治療部位的複數個醫學影像。之後步驟S12被執行,三維影像重組模組4將該等醫學影像進行重組,以形成一三維影像F1。之後步驟S13被執行,病灶範圍取得模組5根據三維影像F1中各區域的HU值,在三維影像上取得一病灶範圍C1。之後步驟S14被執行,導引板生成模組6依照一第一預設值將病灶範圍C1向外擴展,以取得導引板內緣r1。之後步驟S15被執行,導引板生成模組6依照一第二預設值將導引板內緣r1向外擴展,以取得導引板外緣r2。之後步驟S16被執行,導引板生成模組6根據導引板內緣r1及導引板外緣r2,在三維影像F1上映射出導引板內表面s1。之後步驟S17被執行,導引板生成模組6對導引板內表面s1 進行立體化,其自導引板內表面s1上延伸出一導引板厚度t1(導引板厚度t1標示於圖2中),以生成導引板模板10。之後步驟S18被執行,模具製造機台9根據導引板模板10製造出實際的導引板100。藉此,輔助切割的導引板100可自動被生成,可提升醫療手術的精確性。 As shown in FIG. 4 and FIG. 5 , first step S11 is executed, and the medical image acquisition device 3 acquires a plurality of medical images of the parts to be treated of the patient. Then step S12 is executed, the 3D image reconstruction module 4 reconstructs the medical images to form a 3D image F1. Then step S13 is executed, and the lesion range obtaining module 5 obtains a lesion range C1 on the 3D image F1 according to the HU values of each region in the 3D image F1. Then step S14 is executed, and the guide plate generation module 6 expands the lesion range C1 outward according to a first preset value, so as to obtain the inner edge r1 of the guide plate. Then step S15 is executed, and the guide plate generation module 6 expands the inner edge r1 of the guide plate outward according to a second preset value, so as to obtain the outer edge r2 of the guide plate. Then step S16 is executed, and the guide plate generating module 6 maps the inner surface s1 of the guide plate on the three-dimensional image F1 according to the inner edge r1 of the guide plate and the outer edge r2 of the guide plate. Then step S17 is executed, and the guide plate generating module 6 will guide the inner surface s1 of the guide plate Three-dimensionally, a guide plate thickness t1 is extended from the inner surface s1 of the guide plate (thickness t1 of the guide plate is indicated in FIG. 2 ) to generate the guide plate template 10 . Then step S18 is executed, and the mold manufacturing machine 9 manufactures the actual guide plate 100 according to the guide plate template 10 . In this way, the guide plate 100 for auxiliary cutting can be automatically generated, which can improve the accuracy of medical operations.

關於步驟S11,在一些實施例中,醫學影像可例如是多個不同角度的CT影像,且CT影像上的各像素皆有對應的HU值。在一些實施例中,醫學影像取得裝置3可將醫學影像傳送至處理裝置2,其中兩者之間可透過有線傳輸或無線傳輸,且不限於此。 Regarding step S11, in some embodiments, the medical image may be, for example, multiple CT images with different angles, and each pixel on the CT image has a corresponding HU value. In some embodiments, the medical image acquisition device 3 can transmit the medical image to the processing device 2 , and the transmission between the two can be through wired transmission or wireless transmission, and is not limited thereto.

關於步驟S12,在一些實施例中,三維影像重組模組4可採用各種可行的影像處理技術,以利用CT影像來重建患者的待治療部位的三維影像F1。如圖5所示,三維影像F1是以頭顱骨頭做為舉例。本發明不限於此。 Regarding step S12, in some embodiments, the 3D image reconstruction module 4 can use various feasible image processing techniques to reconstruct the 3D image F1 of the patient's part to be treated by using the CT image. As shown in FIG. 5 , the 3D image F1 is taken as an example of a skull. The present invention is not limited thereto.

關於步驟S13,由於人體各介質皆具備相對應的HU值,而病灶處所對應的HU值通常會與其它部位不同,因此在一些實施例中,病灶範圍取得模組5可在三維影像F1上找出HU值離群的像素,並將該等像素的區域定義為病灶,藉此取得病灶範圍C1。本發明不限於此。 Regarding step S13, since each medium of the human body has a corresponding HU value, and the HU value corresponding to the lesion is usually different from other parts, so in some embodiments, the lesion range acquisition module 5 can be found on the three-dimensional image F1 Pixels with outlier HU values are extracted, and the area of these pixels is defined as a lesion, thereby obtaining the lesion range C1. The present invention is not limited thereto.

關於步驟S14,導引板生成模組6可擴展病灶範圍C1,並將擴展後的範圍設為導引板內緣r1,其中導引板內緣r1可視為切割範圍的邊緣;換言之,導引板內緣r1為病灶範圍C1依照特定比例放大的範圍,因此兩者具有相似的輪廓形狀。對病灶範圍C1進行擴展的原因是,由於部分病灶可能是腫瘤,將切割範圍擴大,可降低癌細胞殘留的機率。在一些實施例中,第一預設值可介於0.5至10微米(millimeter,mm)之間(0.5mm≦第一預設值≦10mm),亦即導引板內緣r1為病灶範圍C1向外側擴展0.5至10mm。在一些實施例中,第一預設值可介 於0.5至7.5mm之間(0.5mm≦第一預設值≦7.5mm),亦即導引板內緣r1為病灶範圍C1向外側擴展0.5至7.5mm。在一些實施例中,第一預設值可介於1至5mm之間(1mm≦第一預設值≦5mm),亦即導引板內緣r1為病灶範圍C1向外側擴展1至5mm。上述第一預設值的範圍僅是舉例,並非限定。 Regarding step S14, the guide plate generation module 6 can expand the lesion range C1, and set the expanded range as the inner edge r1 of the guide plate, where the inner edge r1 of the guide plate can be regarded as the edge of the cutting range; in other words, the guide plate The inner edge r1 of the plate is the enlarged range of the lesion range C1 according to a specific ratio, so the two have similar contour shapes. The reason for expanding the range of lesions C1 is that since some lesions may be tumors, expanding the cutting range can reduce the probability of residual cancer cells. In some embodiments, the first preset value can be between 0.5 and 10 microns (millimeter, mm) (0.5mm≦the first preset value≦10mm), that is, the inner edge r1 of the guide plate is the lesion range C1 Expand laterally by 0.5 to 10mm. In some embodiments, the first preset value may be between Between 0.5 and 7.5 mm (0.5 mm≦the first preset value≦7.5 mm), that is, the inner edge r1 of the guide plate extends 0.5 to 7.5 mm outward from the lesion range C1. In some embodiments, the first preset value can be between 1 to 5 mm (1 mm≦first preset value≦5 mm), that is, the inner edge r1 of the guide plate extends 1 to 5 mm outward from the lesion range C1. The above-mentioned range of the first preset value is only an example, not a limitation.

關於步驟S15,此步驟的目的主要是設定導引板100的外框,以使導引板100可穩固地放置於患者的待治療部位處。換言之,導引板外緣r2為導引板內緣r1依照特定比例放大的範圍,因此兩者具有相似的輪廓形狀。在一些實施例中,第二預設值可介於1至5mm之間(1mm≦第二預設值≦5mm),亦即導引板外緣r2為導引板內緣r1向外側擴展1至5mm。在一些實施例中,第二預設值可介於2至4mm之間(2mm≦第二預設值≦4mm),亦即導引板外緣r2為導引板內緣r1向外側擴展2至4mm。在一些實施例中,第一預設值可為3mm(第二預設值=3mm),亦即導引板外緣r2為導引板內緣r1向外側擴展3mm。上述第二預設值的範圍僅是舉例,並非限定。 Regarding step S15 , the purpose of this step is mainly to set the outer frame of the guide plate 100 so that the guide plate 100 can be stably placed on the patient's site to be treated. In other words, the outer edge r2 of the guide plate is an enlarged range of the inner edge r1 of the guide plate according to a specific ratio, so the two have similar contour shapes. In some embodiments, the second preset value can be between 1 and 5mm (1mm≦the second preset value≦5mm), that is, the outer edge r2 of the guide plate is extended by 1 from the inner edge r1 of the guide plate to 5mm. In some embodiments, the second preset value can be between 2 and 4mm (2mm≦the second preset value≦4mm), that is, the outer edge r2 of the guide plate is extended by 2 mm from the inner edge r1 of the guide plate. to 4mm. In some embodiments, the first preset value may be 3mm (the second preset value=3mm), that is, the outer edge r2 of the guide plate extends outward by 3mm from the inner edge r1 of the guide plate. The above-mentioned range of the second preset value is only an example, not a limitation.

關於步驟S16至S17,當取得導引板內緣r1及導引板外緣r2後,導引板生成模組6可將導引板內緣r1與導引板外緣r2之間的範圍定義為導引板內表面s1,並將導引板內表面s1進行立體化,以取得導引板100的建模(即導引板模板10)。在一些實施例中,導引板厚度t1可介於1至5mm(1mm≦t1≦5mm),亦即自導引板內表面s1向上增厚1至5mm的厚度。在一些實施例中,導引板厚度t1可介於2至4mm(2mm≦t1≦4mm),亦即自導引板內表面s1向上增厚2至4mm的厚度。在一些實施例中,導引板厚度t1可介於3mm(t1=3mm),亦即自導引板內表面s1向上增厚3mm的厚度。在一些實施例中,此處「向上增厚」可定義為在導引板內表面s1上,沿著導引板內表面s1的法線方向延伸出厚度t1,但不限於此。據此, 導引板模板10的形狀可與三維影像F1的部位吻合。上述範圍僅是舉例,並非限定。 Regarding steps S16 to S17, after obtaining the inner edge r1 of the guide plate and the outer edge r2 of the guide plate, the guide plate generation module 6 can define the range between the inner edge r1 of the guide plate and the outer edge r2 of the guide plate is the inner surface s1 of the guide plate, and the inner surface s1 of the guide plate is three-dimensionalized to obtain the modeling of the guide plate 100 (ie, the guide plate template 10 ). In some embodiments, the thickness t1 of the guide plate may range from 1 to 5 mm (1 mm≦t1≦5 mm), that is, the thickness increases from the inner surface s1 of the guide plate upwards by 1 to 5 mm. In some embodiments, the thickness t1 of the guide plate may be between 2 to 4 mm (2 mm≦t1≦4 mm), that is, the thickness increases from the inner surface s1 of the guide plate upwards by 2 to 4 mm. In some embodiments, the thickness t1 of the guide plate may be between 3 mm (t1=3 mm), that is, the thickness increases by 3 mm upward from the inner surface s1 of the guide plate. In some embodiments, "thickening upward" here can be defined as extending a thickness t1 along the normal direction of the inner surface s1 of the guide plate on the inner surface s1 of the guide plate, but is not limited thereto. Accordingly, The shape of the guide plate template 10 can match the position of the three-dimensional image F1. The above-mentioned range is only an example and not a limitation.

關於步驟S18,當導引板模板10生成後,處理裝置2可將導引板模板10儲存為模具製造機台9適用的檔案格式,並將導引板模板10的檔案透過有線傳輸或無線傳輸而傳送至模具製造機台9。據此,實際的導引板100可以自動被製造出來。 Regarding step S18, after the guide plate template 10 is generated, the processing device 2 can store the guide plate template 10 as a file format applicable to the mold manufacturing machine 9, and transmit the file of the guide plate template 10 through wired or wireless transmission And be sent to mold making machine platform 9. According to this, the actual guide plate 100 can be manufactured automatically.

在一些實施例中,在步驟S14及步驟S15之間,骨頭切割修補輔助方法可更包含步驟S141。步驟S141為:邊緣優化模組7對導引板內緣r1進行一邊緣平滑化運算,以優化導引板內緣r1。執行步驟S141的目的在於,一般三維影像會以三角網格面的方式呈現,因此進行範圍選取時,例如選取導引板內緣r1時,會受限於三角網格面的影響,讓選取到的範圍呈現不平整的現象。因此步驟S141可對選取範圍進行平滑化處理,使導引板內緣r1的邊界較為平滑。在一些實施例中,邊緣平滑化運算可採用Canny邊緣偵測技術、Sobel邊緣偵測技術,Prewitt邊緣偵測技術、Laplacian邊緣偵測技術或Robert邊緣偵測技術、Snake演算法等實現,且不限於此。 In some embodiments, between step S14 and step S15, the auxiliary method for bone cutting and repair may further include step S141. Step S141 is: the edge optimization module 7 performs an edge smoothing operation on the inner edge r1 of the guide plate to optimize the inner edge r1 of the guide plate. The purpose of executing step S141 is that generally 3D images will be presented in the form of triangular mesh surfaces. Therefore, when performing range selection, for example, when selecting the inner edge r1 of the guide plate, it will be limited by the influence of triangular mesh surfaces, so that the selected The range is uneven. Therefore, in step S141, the selected range can be smoothed to make the boundary of the inner edge r1 of the guide plate smoother. In some embodiments, the edge smoothing operation can be implemented using Canny edge detection technology, Sobel edge detection technology, Prewitt edge detection technology, Laplacian edge detection technology or Robert edge detection technology, Snake algorithm, etc., and does not limited to this.

在一些實施例中,骨頭切割修補輔助方法可更包含步驟S21至步驟S23,其中步驟S21至S23為填補物110的自動生成過程,接著將詳細說明。 In some embodiments, the bone cutting and repairing auxiliary method may further include steps S21 to S23, wherein the steps S21 to S23 are the automatic generation process of the filling 110, which will be described in detail later.

圖6是圖4實施例中步驟S21至S23所對應的示意圖。如圖4及圖6所示,當步驟S14完成後,步驟S21可被執行,填補物生成模組8根據導引板內緣r1在三維影像F1上映射出一填補物外表面s2,其中填補物外表面s2具有與骨頭切割部位一致的弧度。之後步驟S22可被執行,填補物生成模組8對填補物外表面s2進行立體化,自填補物外表面s2延伸出一填補物厚度t2(填補物厚度t2標示於圖 3中),以生成填補物模板11。之後步驟S23可被執行,模具製造機台9可根據填補物模板11製造出實際的填補物110。 FIG. 6 is a schematic diagram corresponding to steps S21 to S23 in the embodiment of FIG. 4 . As shown in Figures 4 and 6, after step S14 is completed, step S21 can be executed, and the filler generation module 8 maps a filler outer surface s2 on the three-dimensional image F1 according to the inner edge r1 of the guide plate, wherein the filler The outer surface s2 has a curvature consistent with the bone cutting site. Afterwards step S22 can be executed, the filler generating module 8 stereotypes the outer surface s2 of the filler, and a filler thickness t2 is extended from the outer surface s2 of the filler (the thickness t2 of the filler is indicated in FIG. 3) to generate the stuffer template 11. Then step S23 can be executed, and the mold manufacturing machine 9 can manufacture the actual filler 110 according to the filler template 11 .

步驟S21至S23的細節可參考步驟S16至S18的說明,故以下僅針對差異處進行說明。在一些實施例中,填補物厚度t2可介於1至5mm(1mm≦t2≦5mm),亦即自填補物外表面s2增厚1至5mm的厚度。在一些實施例中,填補物厚度t2可介於2至4mm(2mm≦t2≦4mm),亦即自填補物外表面s2增厚2至4mm的厚度。在一些實施例中,填補物厚度t2可介於3mm(t1=3mm),亦即自填補物外表面s2增厚3mm的厚度。據此,填補物模板11的形狀可與三維影像F1的部位吻合。在一些實施例中,此處「增厚」可定義為在填補物外表面s2上,沿著填補物外表面s2的法線方向延伸出厚度t2,但不限於此。上述範圍僅是舉例,並非限定。 The details of steps S21 to S23 can refer to the description of steps S16 to S18, so only the differences will be described below. In some embodiments, the thickness t2 of the filling can be between 1 to 5 mm (1 mm≦t2≦5 mm), that is, the thickness increases from the outer surface s2 of the filling to 1 to 5 mm. In some embodiments, the thickness t2 of the filler can be between 2 to 4 mm (2mm≦t2≦4mm), that is, the thickness increases from the outer surface s2 of the filler by 2 to 4 mm. In some embodiments, the thickness t2 of the filling can be between 3 mm (t1=3 mm), that is, the thickness of the filling is increased by 3 mm from the outer surface s2 of the filling. Accordingly, the shape of the filling template 11 can match the position of the 3D image F1. In some embodiments, "thickening" here can be defined as extending a thickness t2 on the outer surface s2 of the filling along the normal direction of the outer surface s2 of the filling, but is not limited thereto. The above-mentioned range is only an example and not a limitation.

據此,填補物110可自動生成。因此當切割手術完成後,醫師即可利用填補物110填補患者受切割的缺口,且填補物110可與切割部位吻合。 Accordingly, the filler 110 can be automatically generated. Therefore, after the cutting operation is completed, the doctor can use the filler 110 to fill up the cut gap of the patient, and the filler 110 can match the cut site.

藉此,透過本發明的輔助,可減少現有切割手術過程的複雜性,並可縮短手術的時間及提升切割的精準度,進而減少併發症的發生。或者,本發明可改善現有填補物難以吻合切割部位的問題。 Thereby, with the assistance of the present invention, the complexity of the existing cutting operation process can be reduced, the operation time can be shortened and the cutting accuracy can be improved, thereby reducing the occurrence of complications. Alternatively, the present invention can improve the problem that existing fillings are difficult to fit the cut site.

上述實施例僅係為了方便說明而舉例而已,本發明所主張之權利範圍自應以申請專利範圍所述為準,而非僅限於上述實施例。 The above-mentioned embodiments are only examples for convenience of description, and the scope of rights claimed by the present invention should be based on the scope of the patent application, rather than limited to the above-mentioned embodiments.

1:骨頭切割修補輔助系統 1: Bone cutting and repairing auxiliary system

2:處理裝置 2: Processing device

3:醫學影像取得裝置 3: Medical image acquisition device

4:三維影像重組模組 4: 3D image reconstruction module

5:病灶範圍取得模組 5: Lesion range acquisition module

6:導引板生成模組 6: Guide plate generation module

7:邊緣優化模組 7: Edge optimization module

8:填補物生成模組 8: Filling generation module

9:模具製造機台 9:Mold making machine

10:導引板模板 10: Guide plate template

11:填補物模板 11: Filler template

20:微處理器 20: Microprocessor

21:電腦程式產品 21:Computer program products

Claims (10)

一種骨頭切割修補輔助系統,包含:一病灶範圍取得模組(5),用於根據一三維影像(F1)上各區域的醫學相關數值,在該三維影像(F1)上取得一病灶範圍(C1);以及一導引板生成模組(6),用於擴展該病灶範圍(C1),以取得一導引板內緣(r1)及一導引板外緣(r2);其中,該導引板生成模組(6)更用於根據該導引板內緣(r1)及該導引板外緣(r2),在該三維影像(F1)上映射出一導引板內表面(s1),以及自該導引板內表面(s1)延伸出一導引板厚度(t1),以生成一導引板模板(10)。 An auxiliary system for bone cutting and repairing, comprising: a lesion area acquisition module (5), used to acquire a lesion area (C1 ); and a guide plate generation module (6), used to expand the lesion range (C1), to obtain a guide plate inner edge (r1) and a guide plate outer edge (r2); wherein, the guide plate The guide plate generation module (6) is further used for mapping an inner surface (s1) of the guide plate on the three-dimensional image (F1) according to the inner edge (r1) and the outer edge (r2) of the guide plate , and a guide plate thickness (t1) is extended from the guide plate inner surface (s1) to generate a guide plate template (10). 如請求項1所述的骨頭切割修補輔助系統,其中更包含一填補物模板生成模組(8),用於根據該導引板內緣(r1),在該三維影像(F1)上取得一填補物外表面(s2),並自該填補物外表面(s2)延伸出一填補物厚度(t2),以生成一填補物模板(11)。 The bone cutting and repairing auxiliary system as described in claim 1, further comprising a filling template generation module (8), used to obtain a three-dimensional image (F1) according to the inner edge (r1) of the guide plate The outer surface of the filling (s2), and a filling thickness (t2) is extended from the outer surface of the filling (s2), so as to generate a filling template (11). 如請求項1所述的骨頭切割修補輔助系統,其中該導引板生成模組(6)是依照一第一預設值將該病灶範圍(C1)向外擴展,以取得該導引板內緣(r1),其中該第一預設值介於0.5至10微米之間。 The auxiliary system for bone cutting and repairing according to claim 1, wherein the guide plate generating module (6) expands the lesion range (C1) outward according to a first preset value, so as to obtain the inside of the guide plate Edge (r1), wherein the first preset value is between 0.5 and 10 microns. 如請求項3所述的骨頭切割修補輔助系統,其中該導引板生成模組(6)是依照一第二預設值將該導引板內緣(r1)向外擴展,以取得該導引板外緣(r2),其中該第二預設值介於1至5微米之間。 The auxiliary system for bone cutting and repairing according to claim 3, wherein the guide plate generating module (6) expands the inner edge (r1) of the guide plate outward according to a second preset value to obtain the guide plate The outer edge (r2) of the lead plate, wherein the second predetermined value is between 1 and 5 microns. 如請求項1所述的骨頭切割修補輔助系統,其中更包含一邊緣優化模組(7),用於對該導引板內緣(r1)執行一邊緣平滑化運算,以優化該導引板內緣(r1)。 The auxiliary system for bone cutting and repairing as described in claim 1, which further includes an edge optimization module (7) for performing an edge smoothing operation on the inner edge (r1) of the guide plate to optimize the guide plate inner edge (r1). 一種骨頭切割修補輔助方法,由一骨頭切割修補輔助系統(1)執行,該方法包含步驟:根據一三維影像(F1)上各區域的一醫學相關數值,在該三維影像(F1)上取得一病灶範圍(C1);將該病灶範圍(C1)向外側擴展,以取得一導引板內緣(r1)及一導引板外緣(r2);以及根據該導引板內緣(r1)及該導引板外緣(r2),在該三維影像(F1)上映射出一導引板內表面(s1),以及自該導引板內表面(s1)延伸出一導引板厚度(t1),以生成一導引板模板(10)。 A bone cutting and repairing auxiliary method, performed by a bone cutting and repairing auxiliary system (1), the method includes the steps of: obtaining a medically relevant value on the three-dimensional image (F1) according to a The lesion range (C1); expand the lesion range (C1) to the outside to obtain an inner edge of the guide plate (r1) and an outer edge of the guide plate (r2); and according to the inner edge of the guide plate (r1) and the outer edge (r2) of the guide plate, a guide plate inner surface (s1) is mapped on the three-dimensional image (F1), and a guide plate thickness (t1) is extended from the guide plate inner surface (s1) ) to generate a guide plate template (10). 如請求項6所述的骨頭切割修補輔助方法,其中更包含步驟:根據該導引板內緣(r1),在該三維影像(F1)上取得一填補物外表面(s2),並自該填補物外表面(s2)延伸出一填補物厚度(t2),以生成一填補物模板(11)。 The auxiliary method for bone cutting and repairing as described in claim 6, which further includes the step of: obtaining an outer surface (s2) of a filler on the three-dimensional image (F1) according to the inner edge (r1) of the guide plate, and from the The outer surface of the filling (s2) is extended by a filling thickness (t2) to generate a filling template (11). 如請求項6所述的骨頭切割修補輔助方法,其中該導引板內緣(r1)是依照一第一預設值將該病灶範圍(C1)向外擴展而取得,其中該第一預設值介於0.5至10微米之間,且該導引板外緣(r2)是依照一第二預設值將該病灶範圍(C1)向外擴展而取得,其中該第二預設值介於1至5微米之間。 The auxiliary method for bone cutting and repair as described in Claim 6, wherein the inner edge (r1) of the guide plate is obtained by expanding the lesion range (C1) outward according to a first preset value, wherein the first preset value The value is between 0.5 and 10 microns, and the outer edge (r2) of the guide plate is obtained by expanding the lesion range (C1) outward according to a second preset value, wherein the second preset value is between Between 1 and 5 microns. 如請求項6所述的骨頭切割修補輔助方法,其中更包含步驟:對該導引板內緣(r1)執行一邊緣平滑化運算,以優化該導引板內緣(r1)。 The auxiliary method for bone cutting and repairing as described in claim 6, further comprising the step of: performing an edge smoothing operation on the inner edge (r1) of the guide plate to optimize the inner edge (r1) of the guide plate. 一種電腦程式產品,儲存於一非暫態電腦可讀取媒介中,用於使一骨頭切割修補輔助系統(1)執行特定程序,其中該電腦程式產品包含: 一第一指令,使該骨頭切割修補輔助系統(1)根據一三維影像(F1)上各區域的一醫學相關數值,在該三維影像(F1)上取得一病灶範圍(C1);一第二指令,使該骨頭切割修補輔助系統(1)將該病灶範圍(C1)向外側擴展,以取得一導引板內緣(r1)及一導引板外緣(r2);一第三指令,使該骨頭切割修補輔助系統(1)根據該導引板內緣(r1)及該導引板外緣(r2),在該三維影像(F1)上映射出一導引板內表面(s1),以及自該導引板內表面(s1)延伸出一導引板厚度(t1),以生成一導引板模板(10)。 A computer program product, stored in a non-transitory computer readable medium, is used to make a bone cutting and repair assisting system (1) execute a specific program, wherein the computer program product includes: A first instruction to make the bone cutting and repairing auxiliary system (1) obtain a lesion range (C1) on the three-dimensional image (F1) according to a medically relevant value of each area on the three-dimensional image (F1); a second command to make the bone cutting and repairing auxiliary system (1) expand the lesion range (C1) to the outside to obtain a guide plate inner edge (r1) and a guide plate outer edge (r2); a third instruction, Make the bone cutting and repairing auxiliary system (1) map an inner surface (s1) of the guide plate on the three-dimensional image (F1) according to the inner edge (r1) and the outer edge (r2) of the guide plate, And a guide plate thickness (t1) is extended from the guide plate inner surface (s1) to generate a guide plate template (10).
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105030297A (en) * 2006-02-06 2015-11-11 康复米斯公司 Patient selectable joint arthroplasty devices and surgical tools
TW200843689A (en) * 2007-05-10 2008-11-16 Univ Chang Gung Apparatus and production method for repairing the medical human bone
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