TWI780838B - Contact lens and contact lens product - Google Patents

Abstract

A contact lens includes at least one color changeable zone, wherein the color changeable zone includes at least one photoluminescence material. Therefore, the color changeable zone of the contact lens of the present disclosure can quickly change the color thereof after absorbing the light at an appropriate wavelength. Accordingly, the contact lens of the present disclosure can immediately react to light, and it is favorable for responding to the change of the ambient light intensity.

Description

Contact lenses and contact lens products

The present invention relates to a contact lens and a contact lens product, in particular to a contact lens and a contact lens product containing a photoluminescence material capable of rapid response.

Conventional contact lenses generally use traditional photochromic compounds for the purpose of light reduction and shading. Due to the poor response speed of traditional photochromic compounds to light, the color change takes more than a few seconds. When the occasion enters a room with weak light, the contact lens remains dark and excessively dims the light. Insufficient light intake will lead to poor vision and may affect safety.

According to the present invention, there is provided a contact lens comprising at least one color-changing region, wherein the aforementioned color-changing region contains at least one photoluminescent substance, and the photoluminescent substance is curcumin or a curcumin derivative. Among them, the average transmittance of the color-changing area at a wavelength of 400 nm to 700 nm is T4070, the total area of the color-changing area is AC, and the total area of the contact lens is AL, which meet the following conditions: 85% ≤ T4070; and 0.001 ≤ AC/AL ≤ 1.0.

According to the present invention, there is also provided a contact lens product, comprising the contact lens described in the preceding paragraph and a light-proof package, wherein the aforementioned contact lens product is a daily disposable.

When T4070 and AC/AL meet the above conditions, the photoluminescent material in the color-changing area of the contact lens of the present invention can quickly achieve a color-changing reaction within 1 second after absorbing light of a corresponding appropriate wavelength, such as changing from yellow to green , so it can immediately respond to and change the light, which helps to quickly respond to changes in the intensity of ambient light. Furthermore, if the contact lens of the present invention is designed to have a photoluminescent material to cover the optical zone, it can effectively convert strong energy UV light into weaker energy light to protect the retina and reduce damage.

The invention provides a contact lens comprising at least one color-changing region, wherein the color-changing region contains at least one photoluminescent substance. In detail, when light of appropriate wavelength irradiates a photoluminescent substance or other molecules with fluorescent properties, the molecules in the substance will absorb the energy of the light and be excited to a high-energy state, and the molecules in the high-energy state will be in the extreme Restore the low-energy state in a short time, and at the same time release excess energy in the form of light.

In the contact lens of the present invention, wherein the wavelength of the photoluminescent substance with the maximum radiation intensity is WEmMx, the average transmittance of the discoloration zone at a wavelength of 400 nm to 700 nm is T4070, the total area of the discoloration zone is AC, the contact lens The total area is AL, which satisfies the following conditions: 400 nm ≤ WEmMx ≤ 600 nm; 85% ≤ T4070; and 0.001 ≤ AC/AL ≤ 1.0. Thereby, after the photoluminescence material of the contact lens of the present invention absorbs the light of the appropriate wavelength, it can quickly achieve a color change reaction within 1 second, such as changing from yellow to green, so it can immediately respond to and change the light, effectively It helps to quickly respond to changes in the intensity of ambient light. Furthermore, if the photoluminescent material is designed to cover the optical zone, it can effectively convert the strong-energy UV light into weaker-energy light, so as to protect the retina and reduce damage.

Alternatively, the wavelength of the photoluminescent substance having the maximum radiation intensity is WEmMx, which can satisfy the following condition: 480 nm ≤ WEmMx ≤ 580 nm. Alternatively, it may satisfy the following condition: 500 nm ≤ WEmMx ≤ 560 nm. Alternatively, it may satisfy the following condition: 520 nm ≤ WEmMx ≤ 550 nm. Alternatively, it may satisfy the following condition: 520 nm ≤ WEmMx ≤ 540 nm.

Alternatively, the average transmittance of the color-changing region at a wavelength of 400 nm to 700 nm is T4070, which can meet the following conditions: 40% ≤ T4070 ≤ 94%. Alternatively, it may satisfy the following condition: 50% ≤ T4070 ≤ 90%. Alternatively, it may satisfy the following condition: 60% ≤ T4070 ≤ 89%. Alternatively, it may satisfy the following condition: 70% ≤ T4070 ≤ 88%.

Alternatively, the total area of the discoloration zone is AC and the total area of the contact lens is AL, which may satisfy the following condition: 0.05 ≤ AC/AL ≤ 0.5. In this way, a small-scale color-changing area is set, so that the color-changing area has special functions such as indication and identification. Alternatively, it may satisfy the following condition: 0.5 < AC/AL ≤ 1.0. In this way, a large-scale discoloration area is set, so that the discoloration area has a large-scale color change effect, and has the function of eliminating stray light and absorbing ultraviolet light in the optical area. Alternatively, it may satisfy the following condition: 0.1 ≤ AC/AL ≤ 0.5. Alternatively, it may satisfy the following condition: 0.2 ≤ AC/AL ≤ 0.9. Alternatively, it may satisfy the following condition: 0.3 ≤ AC/AL ≤ 0.7. Alternatively, it may satisfy the following condition: 0.4 ≤ AC/AL ≤ 0.6.

Furthermore, when the color-changing region of the present invention is ring-shaped, it can be designed as a single-ring structure or a multi-ring structure, wherein the gradient between the multi-ring structures can be blank, or the multi-ring structures are directly adjacent to each other. The inner or outer ring of the structure or multi-ring structure may be polygonal (eg, octagonal, etc.). Furthermore, when the color-changing area is a multi-ring structure, the multi-ring structure can use different concentrations to achieve a gradient design, and the color can change from dark to light, from light to dark, from deep to light and then to deep, from light to deep and then to light , and can also change alternately or leave a blank transparent part. When the color-changing area is a single-ring structure, it can also present a gradient design, and it can also have the function of identifying the direction of rotation. And when the discoloration area is disc-shaped, the dimming effect can be adjusted as required.

According to the contact lens of the present invention, wherein the photoluminescent substance can be curcumin (curcumin, (1E, 6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5- dione) or curcuminoid derivatives (curcuminoid). Therefore, the photoluminescence material of the contact lens of the present invention has high biocompatibility and low toxicity, and can reduce eye irritation and damage.

   式(I)、

   式(II)。 其中光致發光物質的側鏈為-X-R¹ 或-X-R² 或-X-R³ ，R¹ 或R² 或R³ 中至少一者為飽和碳鏈或不飽和碳鏈，X為氧或氮，且光致發光物質的一側鏈含碳數量為NC，其可滿足下列條件：1 ≤ NC ≤ 18。藉此，可增加光致發光物質於隱形眼鏡製作時的相容性，使單體材料可與光致發光物質直接鍵結。或者，其可滿足下列條件：1 ≤ NC ≤ 10。藉此，含碳數量較少的側鏈長度具有較佳的溶解性，較易於製作時光致發光物質與材料互溶。或者，其可滿足下列條件：11 ≤ NC ≤ 18。藉此，含碳數量較多的側鏈長度具有較佳的鍵結效率，有助於光致發光物質與單體材料鍵結。再者，當光致發光物質改質(接枝)後，可與隱形眼鏡的單體材料共同製作成型，使本發明之隱形眼鏡成品內含有的光致發光物質具有不會擴散到隱形眼鏡外的效果，但本發明並不以此為限。According to the contact lens of the present invention, wherein the aforementioned photoluminescent substance can have a structure as shown in formula (I) or formula (II):

Formula (I),

Formula (II). Wherein the side chain of the photoluminescent substance is -XR ¹ or -XR ² or -XR ³ , at least one of R ¹ or R ² or R ³ is a saturated carbon chain or an unsaturated carbon chain, X is oxygen or nitrogen, and The carbon number of the side chain of the photoluminescent substance is NC, which can satisfy the following conditions: 1 ≤ NC ≤ 18. In this way, the compatibility of the photoluminescent substance in the manufacture of contact lenses can be increased, so that the monomer material can be directly bonded to the photoluminescent substance. Alternatively, it may satisfy the following condition: 1 ≤ NC ≤ 10. Thereby, the length of the side chain with less carbon content has better solubility, and it is easier to make the photoluminescent substance and the material to be miscible. Alternatively, it may satisfy the following condition: 11 ≤ NC ≤ 18. Thereby, the length of the side chain with more carbon content has better bonding efficiency, which is helpful for the bonding of the photoluminescent substance and the monomer material. Furthermore, after the photoluminescent substance is modified (grafted), it can be co-produced with the monomer material of the contact lens, so that the photoluminescent substance contained in the finished contact lens of the present invention will not diffuse outside the contact lens. effect, but the present invention is not limited thereto.

In the side chain -XR ¹ , -XR ² or -XR ³ of the photoluminescent substance, at least one of R ¹ or R ² or R ³ is an unsaturated carbon chain. Thereby, it has better oxidation ability to increase the bonding efficiency of photoluminescent substance modification and contact lens material monomers. Alternatively, at least one of the side chains -XR ¹ , -XR ² or -XR ³ of the photoluminescent substance is an etheroxy group (-O-). Thereby, it is helpful to improve the bonding compatibility between the photoluminescent substance and the monomer material. Alternatively, at least one of the side chains -XR ¹ , -XR ² or -XR ³ of the photoluminescent substance is silyloxy (-SiO-). Thereby, it is helpful to improve the bonding compatibility between the photoluminescent substance and the silicone hydrocolloid monomer material.

According to the contact lens of the present invention, a metal ion may be further included, and the photoluminescent substance is bonded with the metal ion to form a metal ion complex. The aforementioned metal ions may be metal ions such as Cu ²⁺ or Fe ³⁺ . In this way, the acidity and alkalinity can be effectively indicated by the color change.

The contact lens according to the present invention may further comprise at least one antioxidant. Specifically, the luminescence lifetime of the photoluminescent substance is not affected by the intensity of the excitation light, but adding an antioxidant can effectively prolong the service life of the contact lens with the photoluminescent substance.

According to the contact lens of the present invention, wherein the weight percentage of the aforementioned photoluminescent substance in the contact lens is WP, which can satisfy the following conditions: 0.01% ≤ WP ≤ 1.0%. In this way, through the optimal concentration configuration of photoluminescent substances in contact lenses, the absorption effect of photoluminescent substances can be exerted to reduce the damage of high-energy light and enhance the elimination of glare while maintaining the requirement of optimal transmittance Effect. Alternatively, it may satisfy the following condition: 0.05% ≤ WP ≤ 0.40%. Alternatively, it may satisfy the following condition: 0.09% ≤ WP ≤ 0.30%. Alternatively, it may satisfy the following condition: 0.15% ≤ WP ≤ 0.25%.

According to the contact lens of the present invention, the material of the contact lens can be hydrogel or silicon hydrogel, and the contact lens is cured by light. In this way, photocuring can be used to manufacture contact lenses, and the activity of photoluminescent substances can be effectively maintained at an appropriate concentration of photoluminescent substances.

According to the contact lens of the present invention, the contact lens may comprise at least three lens layers, and the color-changing region is disposed on the middle lens layer among the aforementioned at least three lens layers. Thereby, leakage of the photoluminescent substance or colorant in the contact lens can be avoided, and the chance of contacting the chemical substance with the eyes can be reduced.

According to the contact lens of the present invention, the discoloration region may contain at least one colorant. In this way, the color-changing area can mix the photoluminescent substance with the coloring material, so that the color-changing area can achieve different color changes as required. If the discoloration area is designed as a ring smaller than the optical area, it will help reduce stray light. When applied to multifocal contact lenses with slowing down and vision control, it can eliminate glare. If the discoloration area is designed as a disc and covers The optical area can block strong light to achieve the light reduction effect of sunglasses. If the discoloration area is further designed in the outer area of the non-optical area, it can adjust the appearance of the contact lens to achieve the iris magnification effect. Preferably, the color of the pigment can be blue, gold, green, brown, black, gray, purple, platinum, yellow, red, pink, brown, brownish brown or orange, but the present invention does not limit.

According to the contact lens of the present invention, the color-changing region may contain at least two photoluminescent substances. It may be Coumarin, Eosin, Fluorescein, Green fluorescent protein, Hoechst stains, Phycocyanin, algae Phycoerythrin, Pyranine, Rhodamine B, or TINOPAL. In this way, photoluminescent substances can be adjusted and selected according to the desired discoloration effect. Mixing multiple photoluminescent substances can achieve different color change performances, and the coloring material and photoluminescent substances can be stored in the same lens layer of the contact lens. The yellow photoluminescent substance mixed with the blue colorant can appear black.

According to the contact lens of the present invention, wherein the total area of the discoloration zone is AC, which can satisfy the following condition: 5 mm ² ≤ AC ≤ 200 mm ² . Thereby, the range of the discoloration area can be adjusted appropriately. Alternatively, it may satisfy the following condition: 25 mm ² ≤ AC ≤ 150 mm ² . Alternatively, it may satisfy the following condition: 50 mm ² ≤ AC ≤ 140 mm ² . Alternatively, it may satisfy the following condition: 70 mm ² ≤ AC ≤ 120 mm ² .

According to the contact lens of the present invention, wherein the maximum diameter of the discoloration zone is DPmax, which can satisfy the following condition: 1 mm ≤ DPmax ≤ 16 mm. Thereby, the color changing area can provide a wide range of color changing effects. Alternatively, it may satisfy the following condition: 3 mm ≤ DPmax ≤ 14 mm. Alternatively, it may satisfy the following condition: 5 mm ≤ DPmax ≤ 13 mm. Alternatively, it may satisfy the following condition: 10 mm ≤ DPmax ≤ 12 mm.

According to the contact lens of the present invention, wherein the maximum diameter of the discoloration area is DPmax, and the diameter of the contact lens is D, which can satisfy the following condition: 0.05 ≤ DPmax/D ≤ 1.00. Thereby, the range of the color-changing area can be adjusted appropriately, and the required color-changing range can be adjusted according to requirements, so as to provide a wide range of color changing effects. Alternatively, it may satisfy the following condition: 0.05 ≤ DPmax/D ≤ 0.5. Alternatively, it may satisfy the following condition: 0.2 ≤ DPmax/D ≤ 0.9. Alternatively, it may satisfy the following condition: 0.3 ≤ DPmax/D ≤ 0.7. Alternatively, it may satisfy the following condition: 0.4 ≤ DPmax/D ≤ 0.6.

According to the contact lens of the present invention, wherein the minimum diameter of the discoloration zone is DPmin, which can satisfy the following condition: 0 mm ≤ DPmin ≤ 13 mm. In this way, the color-changing area can absorb ultraviolet light to reduce eye damage. Alternatively, it may satisfy the following condition: 2 mm ≤ DPmin ≤ 12 mm. Alternatively, it may satisfy the following condition: 3 mm ≤ DPmin ≤ 10 mm. Alternatively, it may satisfy the following condition: 5 mm ≤ DPmin ≤ 8 mm.

According to the contact lens of the present invention, wherein the minimum diameter of the discoloration area is DPmin, and the diameter of the contact lens is D, which can satisfy the following condition: 0 ≤ DPmin/D ≤ 0.9. In this way, the circular range of the discoloration area can be adjusted according to the needs, which helps to improve the effect of stray light elimination. When the discoloration area covers the optical area, it can absorb ultraviolet light to reduce eye damage. Alternatively, it may satisfy the following condition: 0.1 ≤ DPmin/D ≤ 0.8. Alternatively, it may satisfy the following condition: 0.2 ≤ DPmin/D ≤ 0.7. Alternatively, it may satisfy the following condition: 0.4 ≤ DPmin/D ≤ 0.6.

According to the contact lens of the present invention, wherein the maximum diameter of the discoloration area is DPmax, and the minimum diameter of the discoloration area is DPmin, which can satisfy the following condition: 0 ≤ DPmax/DPmin ≤ 0.99. As a result, the color-changing zones help improve stray light cancellation and reduce eye damage. Alternatively, it may satisfy the following condition: 0.1 ≤ DPmax/DPmin ≤ 0.9. Alternatively, it may satisfy the following condition: 0.3 ≤ DPmax/DPmin ≤ 0.8. Alternatively, it may satisfy the following condition: 0.4 ≤ DPmax/DPmin ≤ 0.6.

According to the contact lens of the present invention, the average transmittance of the color-changing region at a wavelength of 380 nm to 480 nm is T3848, which can satisfy the following conditions: 30% ≤ T3848 ≤ 90%. Thereby, the usage amount of the photoluminescent substance can be adjusted appropriately, and the absorption effect of the shorter-wavelength visible light in the color-changing region can be effectively improved. Alternatively, it may satisfy the following condition: 50% ≤ T3848 ≤ 89%. Alternatively, it may satisfy the following condition: 60% ≤ T3848 ≤ 85%.

According to the contact lens of the present invention, the average transmittance of the color-changing region at a wavelength of 280 nm to 400 nm is T2840, which can satisfy the following conditions: 5% ≤ T2840 ≤ 20%. In this way, the absorption effect of the color-changing region on short-wavelength light can be effectively improved. Alternatively, it may satisfy the following condition: 10% ≤ T2840 ≤ 20%.

According to the contact lens of the present invention, the average transmittance of the color-changing region at a wavelength of 300 nm to 400 nm is T3040, which can satisfy the following conditions: 5% ≤ T3040 ≤ 20%. In this way, the absorption effect of the color-changing region on short-wavelength light can be effectively improved. Alternatively, it may satisfy the following condition: 10% ≤ T3040 ≤ 20%.

According to the contact lens of the present invention, the average transmittance of the color-changing region at a wavelength of 380 nm to 500 nm is T3850, which can satisfy the following conditions: 30% ≤ T3850 ≤ 90%. Thereby, the absorption effect of the color-changing region on shorter-wavelength visible light can be effectively improved. Alternatively, it may satisfy the following condition: 50% ≤ T3850 ≤ 89%. Alternatively, it may satisfy the following condition: 60% ≤ T3850 ≤ 85%.

According to the contact lens of the present invention, the average transmittance of the color-changing region at a wavelength of 400 nm to 500 nm is T4050, which can satisfy the following conditions: 40% ≤ T4050 ≤ 94%. Thereby, the absorption effect of the color-changing region on blue visible light can be effectively improved. Alternatively, it may satisfy the following condition: 50% ≤ T4050 ≤ 90%. Alternatively, it may satisfy the following condition: 60% ≤ T4050 ≤ 89%. Alternatively, it may satisfy the following condition: 70% ≤ T4050 ≤ 88%.

According to the contact lens of the present invention, the average transmittance of the color-changing region at a wavelength of 400 nm to 550 nm is T4055, which can satisfy the following conditions: 40% ≤ T4055 ≤ 94%. Thereby, the absorption effect of the color-changing region on blue visible light can be effectively improved. Alternatively, it may satisfy the following condition: 50% ≤ T4055 ≤ 90%. Alternatively, it may satisfy the following condition: 60% ≤ T4055 ≤ 89%. Alternatively, it may satisfy the following condition: 70% ≤ T4055 ≤ 88%.

According to the contact lens of the present invention, the average transmittance of the color-changing region at a wavelength of 400 nm to 700 nm is T4070, which can satisfy the following conditions: 40% ≤ T4070 ≤ 94%. Thereby, the absorption effect of the color-changing region on visible light can be effectively improved. Alternatively, it may satisfy the following condition: 50% ≤ T4070 ≤ 90%. Alternatively, it may satisfy the following condition: 60% ≤ T4070 ≤ 89%. Alternatively, it may satisfy the following condition: 70% ≤ T4070 ≤ 88%.

According to the contact lens of the present invention, the average absorption value of the color-changing region at a wavelength of 380 nm to 500 nm is A3850, which can satisfy the following condition: 0.05 ≤ A3850. In this way, the color-changing region has better absorption value in a specific wavelength range, so that the color-changing region of the contact lens exhibits desired color performance. Alternatively, it may satisfy the following condition: 0.1 ≤ A3850. Alternatively, it may satisfy the following condition: 0.25 ≤ A3850. Alternatively, it may satisfy the following condition: 0.4 ≤ A3850.

According to the contact lens of the present invention, the average absorption value of the color-changing region at a wavelength of 380 nm to 480 nm is A3848, which can satisfy the following condition: 0.05 ≤ A3848. In this way, the usage amount of the photoluminescent substance can be adjusted appropriately, and the absorption effect of the color-changing region on shorter-wavelength visible light can be effectively improved. Alternatively, it may satisfy the following condition: 0.1 ≤ A3848. Alternatively, it may satisfy the following condition: 0.25 ≤ A3848. Alternatively, it may satisfy the following condition: 0.4 ≤ A3848.

According to the contact lens of the present invention, the average absorption value of the color-changing region at a wavelength of 400 nm to 500 nm is A4050, which can satisfy the following condition: 0.05 ≤ A4050. Thereby, the absorption effect of the color-changing region on blue visible light can be effectively improved. Alternatively, it may satisfy the following condition: 0.1 ≤ A4050. Alternatively, it may satisfy the following condition: 0.25 ≤ A4050.

According to the contact lens of the present invention, the average absorption value of the color-changing region at a wavelength of 400 nm to 550 nm is A4055, which can satisfy the following condition: 0.05 ≤ A4055. Thereby, the absorption effect of the color-changing region on blue visible light can be effectively improved. Alternatively, it may satisfy the following condition: 0.1 ≤ A4055. Alternatively, it may satisfy the following condition: 0.25 ≤ A4055.

According to the contact lens of the present invention, the average absorption value of the color-changing region at a wavelength of 400 nm to 700 nm is A4070, which can satisfy the following conditions: 0.05 ≤ A4070 ≤ 0.25. Thereby, the absorption and transmission of visible light in the discoloration region can be effectively balanced. Alternatively, it may satisfy the following condition: 0.1 ≤ A4070 ≤ 0.20.

According to the contact lens of the present invention, the average absorption value of the color-changing region at a wavelength of 450 nm to 650 nm is A4565, which can satisfy the following condition: A4565 ≤ 0.05. Thereby, the high penetration of green/red visible light in the color changing area is effectively maintained. Alternatively, it may satisfy the following condition: 0.1 ≤ A4565.

According to the contact lens of the present invention, at least one color changing area is a pattern. In detail, the aforesaid patterns can be characters (such as GOOD), numbers, patterns, stripes, polygons, circles, etc., but the present invention is not limited thereto. In this way, the pattern can have directional and representative functions, and can produce effects such as identification marks, expiration date indication, direction identification, and indication of possible environmental hazards.

All the technical features of the above-mentioned contact lens of the present invention can be configured in combination to achieve corresponding effects.

The present invention provides a contact lens product, comprising the aforementioned contact lens and a light-proof package. Among them, the aforementioned contact lens products are daily disposable. In detail, since the photoluminescent substance may lose its luminous effect over time after being exposed to light, it should be used within the maximum active period of the photoluminescent substance to maintain the best light-shielding or light-reducing effect, and the packaging should be completely protected from light Blocking light can protect and maintain the photoluminescent substance in the contact lens, which helps to preserve for a long time and maintain the best light-shielding or light-reducing effect.

According to the above-mentioned implementation manners, specific embodiments are proposed below and described in detail with reference to the drawings.

[contact lenses]

Different structural embodiments of the contact lens of the present invention will be proposed in detail below.

<First structure example>

Please refer to FIG. 1 , which is a schematic diagram of a contact lens 100 according to a first structural embodiment of the present invention. The contact lens 100 includes an optical zone 110 and a color changing zone 120 .

The optical zone 110 is located at the center of the contact lens 100 , the discoloration zone 120 is disc-shaped, and the maximum diameter of the discoloration zone 120 is larger than the maximum diameter of the optic zone 110 .

The color-changing area 120 contains at least one photoluminescent substance, and the material for making the contact lens 100 is hydrogel, and the contact lens 100 is cured by light, and in the first figure, the sprinkle point of the contact lens 100 represents the color-changing area 120 The photoluminescent substance is only for illustration, and the size and distribution of the dots are not used to represent the particle size, concentration or type of the photoluminescent substance, which will be described here. In this way, the photoluminescent substance covers the optical region 110, which can effectively convert the strong energy UV light into weaker energy light, so as to protect the retina and reduce damage.

In the contact lens 100, the total area of the discoloration zone 120 is AC, the total area of the contact lens 100 is AL, the maximum diameter of the discoloration zone 120 is DPmax, the minimum diameter of the discoloration zone 120 is DPmin, and the diameter of the contact lens 100 is D, It satisfies the following conditions: AC = 165 mm ² ; AL = 165 mm ² ; DPmax = 14.50 mm; DPmin = 0 mm; D = 14.50 mm; AC/AL = 1.00 mm; DPmax/D = 1.00; DPmin/D = 0 ; and DPmin/DPmax = 0.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Second structure example>

Please refer to FIG. 2 , which is a schematic diagram of a contact lens 200 according to a second structural embodiment of the present invention. The contact lens 200 includes an optical zone 210 and a color changing zone 220 .

The optical zone 210 is located at the center of the contact lens 200 , and the discoloration zone 220 is disc-shaped and concentric with the optic zone 210 , wherein the maximum diameter of the discoloration zone 220 is smaller than the maximum diameter of the optic zone 210 .

In the contact lens 200, the color-changing area 220 contains at least one photoluminescent substance, and the material for making the contact lens 200 is hydrogel, and the contact lens 200 is cured by light, and in the second figure, the spray of the contact lens 200 The dots represent the photoluminescent substance in the color-changing area 220, and the blank spaces represent the area of the contact lens 200 not covered by the color-changing region 220, and the dots are only for illustration, and the size and distribution of the dots are not used to represent the photoluminescent material. Particle size, concentration or type are described here first. In addition, the following embodiments are the same and will not be described again.

In the contact lens 200, the total area of the discoloration zone 220 is AC, the total area of the contact lens 200 is AL, the maximum diameter of the discoloration zone 220 is DPmax, the minimum diameter of the discoloration zone 220 is DPmin, and the diameter of the contact lens 200 is D, It satisfies the following conditions: AC = 38 mm ² ; AL = 165 mm ² ; DPmax = 7.00 mm; DPmin = 0 mm; D = 14.50 mm; AC/AL = 0.23 mm; DPmax/D = 0.48; DPmin/D = 0 ; and DPmin/DPmax = 0.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Third structural example>

Please refer to FIG. 3 , which is a schematic diagram of a contact lens 300 according to a third structural embodiment of the present invention. The contact lens 300 includes an optical zone 310 and a color changing zone 320 .

The optical zone 310 is located at the center of the contact lens 300, and the discoloration zone 320 is arranged concentrically with the optic zone 310, wherein the discoloration zone 320 is a single ring structure, and the maximum diameter of the discoloration zone 320 is greater than the maximum diameter of the optic zone 310, and the minimum diameter of the discoloration zone 320 is smaller than the maximum diameter of the optic zone 310 .

In the contact lens 300, the discoloration area 320 contains at least one photoluminescent substance (the dots in the 3rd figure represent the photoluminescent substance), and the material for making the contact lens 300 is hydrogel, and the contact lens 300 is made of light. solidified.

In the contact lens 300, the total area of the discoloration zone 320 is AC, the total area of the contact lens 300 is AL, the maximum diameter of the discoloration zone 320 is DPmax, the minimum diameter of the discoloration zone 320 is DPmin, and the diameter of the contact lens 300 is D, It satisfies the following conditions: AC = 110 mm ² ; AL = 165 mm ² ; DPmax = 12.74 mm; DPmin = 4.69 mm; D = 14.50 mm; AC/AL = 0.67 mm; DPmax/D = 0.88; DPmin/D = 0.32 ; and DPmin/DPmax = 0.37.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Fourth structural example>

Please refer to FIG. 4 , which is a schematic diagram of a contact lens 400 according to a fourth structural embodiment of the present invention. The contact lens 400 includes an optical zone 410 and a color changing zone 420 .

The optical zone 410 is located at the center of the contact lens 400, and the discoloration zone 420 is arranged concentrically with the optic zone 410, wherein the discoloration zone 420 is a single-ring structure, the maximum diameter of the discoloration zone 420 is larger than the maximum diameter of the optic zone 410, and the minimum diameter of the discoloration zone 420 is Smaller than the largest diameter of optic zone 410 .

In the contact lens 400, the color-changing area 420 contains at least one photoluminescent substance (the dots in Fig. 4 indicate the photoluminescent substance), and the material for making the contact lens 400 is hydrogel, and the contact lens 400 is made of light. solidified.

In the contact lens 400, the total area of the discoloration zone 420 is AC, the total area of the contact lens 400 is AL, the maximum diameter of the discoloration zone 420 is DPmax, the minimum diameter of the discoloration zone 420 is DPmin, and the diameter of the contact lens 400 is D, It satisfies the following conditions: AC = 72 mm ² ; AL = 165 mm ² ; DPmax = 9.76 mm; DPmin = 1.88 mm; D = 14.50 mm; AC/AL = 0.44 mm; DPmax/D = 0.67; DPmin/D = 0.13 ; and DPmin/DPmax = 0.19.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Fifth Structural Example>

Please refer to FIG. 5 , which is a schematic diagram of a contact lens 500 according to a fifth structural embodiment of the present invention. The contact lens 500 includes an optical zone 510 and a color changing zone 520 .

The optical zone 510 is located at the center of the contact lens 500, and the discoloration zone 520 is arranged concentrically with the optic zone 510, wherein the discoloration zone 520 is a single ring structure, the inner ring of the discoloration zone 520 is a decagon, and the maximum diameter of the discoloration zone 520 is larger than that of the optic zone 510 The maximum diameter of the discoloration zone 520 is smaller than the maximum diameter of the optical zone 510.

In the contact lens 500, the color-changing area 520 contains at least one photoluminescent substance (the dots in Fig. 5 represent the photoluminescent substance), and the material for making the contact lens 500 is hydrogel, and the contact lens 500 is made of light. solidified.

In the contact lens 500, the total area of the discoloration zone 520 is AC, the total area of the contact lens 500 is AL, the maximum diameter of the discoloration zone 520 is DPmax, the minimum diameter of the discoloration zone 520 is DPmin, and the diameter of the contact lens 500 is D, It satisfies the following conditions: AC = 135 mm ² ; AL = 165 mm ² ; DPmax = 13.70 mm; DPmin = 3.90 mm; D = 14.50 mm; AC/AL = 0.82 mm; DPmax/D = 0.94; DPmin/D = 0.27 ; and DPmin/DPmax = 0.28.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Sixth Structural Example>

Please refer to FIG. 6 , which is a schematic diagram of a contact lens 600 according to a sixth structural embodiment of the present invention. The contact lens 600 includes an optical zone 610 , a color changing zone 620 and a pattern changing color zone 630 .

The optical zone 610 is located at the center of the contact lens 600, and the discoloration zone 620 is arranged concentrically with the optic zone 610, wherein the discoloration zone 620 is a single ring structure, and the maximum diameter of the discoloration zone 620 is larger than the maximum diameter of the optic zone 610, and the minimum diameter of the discoloration zone 620 is smaller than the maximum diameter of the optical zone 610, and the pattern color-changing zone 630 is the text "GOOD".

In the contact lens 600, the color-changing area 620 and the pattern-changing area 630 contain at least one photoluminescent substance (the dots in the color-changing area 620 in Figure 6 represent photoluminescent substances), and the material for making the contact lens 600 is hydrogel, And the contact lens 600 is cured by light.

In the contact lens 600, the total area of the discoloration zone 620 is AC, the total area of the contact lens 600 is AL, the maximum diameter of the discoloration zone 620 is DPmax, the minimum diameter of the discoloration zone 620 is DPmin, and the diameter of the contact lens 600 is D, It satisfies the following conditions: AC = 12 mm ² ; AL = 165 mm ² ; DPmax = 8.28 mm; DPmin = 7.29 mm; D = 14.50 mm; AC/AL = 0.08 mm; DPmax/D = 0.57; DPmin/D = 0.50 ; and DPmin/DPmax = 0.88.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Seventh Structural Example>

Please refer to FIG. 7 , which is a schematic diagram of a contact lens 700 according to a seventh structural embodiment of the present invention. The contact lens 700 includes an optical zone 710 and a color changing zone 720 .

The optical zone 710 is located at the center of the contact lens 700 , and the discoloration zone 720 is concentric with the optic zone 710 , wherein the discoloration zone 720 is a single ring structure, and the smallest diameter of the discoloration zone 720 is larger than the largest diameter of the optic zone 710 .

In the contact lens 700, the color-changing area 720 contains at least one photoluminescent substance (the dots in Fig. 7 represent the photoluminescent substance), and the material for making the contact lens 700 is hydrogel, and the contact lens 700 is made of light. solidified.

In the contact lens 700, the total area of the discoloration zone 720 is AC, the total area of the contact lens 700 is AL, the maximum diameter of the discoloration zone 720 is DPmax, the minimum diameter of the discoloration zone 720 is DPmin, and the diameter of the contact lens 700 is D, It satisfies the following conditions: AC = 58 mm ² ; AL = 165 mm ² ; DPmax = 14.11 mm; DPmin = 11.17 mm; D = 14.50 mm; AC/AL = 0.35 mm; DPmax/D = 0.97; DPmin/D = 0.77 ; and DPmin/DPmax = 0.79.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Eighth Structural Embodiment>

Please refer to FIG. 8 , which is a schematic diagram of a contact lens 800 according to an eighth structural embodiment of the present invention. The contact lens 800 includes an optical zone 810 and a color changing zone 820 .

The optical zone 810 is located at the center of the contact lens 800, and the color-changing zone 820 is concentrically arranged with the optical zone 810, wherein the color-changing zone 820 is a multi-ring structure, and the gradient between the multi-ring structures is configured as a blank transparent part, and each single ring structure of the multi-ring structure The color of the ring has alternating changes in depth and light, and a blank transparent part can also be configured in a single ring. The maximum diameter of the discoloration zone 820 is larger than the maximum diameter of the optic zone 810 , and the minimum diameter of the discoloration zone 820 is smaller than the maximum diameter of the optic zone 810 .

In the contact lens 800, the color-changing area 820 contains at least one photoluminescent substance (the dots in Fig. 8 indicate the photoluminescent substance), and the material for making the contact lens 800 is hydrogel, and the contact lens 800 is made of light. solidified.

In the contact lens 800, the total area of the discoloration zone 820 is AC, the total area of the contact lens 800 is AL, the maximum diameter of the discoloration zone 820 is DPmax, the minimum diameter of the discoloration zone 820 is DPmin, the diameter of the contact lens 800 is D, It satisfies the following conditions: AC = 93 mm ² ; AL = 165 mm ² ; DPmax = 12.33 mm; DPmin = 5.18 mm; D = 14.50 mm; AC/AL = 0.57 mm; DPmax/D = 0.85; DPmin/D = 0.36 ; and DPmin/DPmax = 0.42.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Ninth Structural Embodiment>

Please refer to FIG. 9 , which is a schematic cross-sectional view of a contact lens 900 according to a ninth structural embodiment of the present invention. The contact lens 900 includes an optical zone (not shown in the figure) and a discoloration zone 920. The discoloration zone 920 includes at least one photoluminescent substance (the dots in FIG. 9 represent the photoluminescent substance), wherein the shape of the discoloration zone 920 is The disc shape is arranged concentrically with the optical zone, and other relevant details of the discoloration zone 920 can be found in the above, and will not be repeated here.

As shown in FIG. 9 , the contact lens 900 sequentially includes a first lens layer 901 and a second lens layer 902 from the side away from the eyeball to the side close to the eyeball. The discoloration area 920 is disposed on the first lens layer 901 .

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Tenth Structural Example>

Please refer to FIG. 10 , which is a schematic cross-sectional view of a contact lens 1000 according to a tenth structural embodiment of the present invention. The contact lens 1000 includes an optical zone (not shown in the figure) and a color-changing zone 1020. The color-changing zone 1020 includes at least one photoluminescent substance (the dots in Figure 10 represent the photoluminescent substance), wherein the shape of the color-changing zone 1020 is The disc shape is set concentrically with the optical zone, and other relevant details of the discoloration zone 1020 can be referred to above, and will not be repeated here.

As shown in Figure 10, the contact lens 1000 includes a first lens layer 1001, a second lens layer 1002, and a third lens layer 1003 from the side away from the eyeball to the side close to the eyeball, and the discoloration area 1020 is set. The second lens layer 1002 in the middle.

For details about the photoluminescent substance, please refer to the above, and will not be repeated here.

<Eleventh structure example>

Please refer to FIG. 11 , which is a schematic cross-sectional view of a contact lens 1100 according to an eleventh structure embodiment of the present invention. The contact lens 1100 includes an optical zone (not shown in the figure) and a color-changing zone 1120. The color-changing zone 1120 includes at least one photoluminescent substance (the dots in FIG. 11 represent the photoluminescent substance), wherein the color-changing zone 1120 is a single ring The structure is arranged concentrically with the optical zone, and other relevant details of the discoloration zone 1120 can be referred to above, and will not be repeated here.

As shown in Figure 11, the contact lens 1100 includes a first lens layer 1101, a second lens layer 1102, and a third lens layer 1103 in order from the side away from the eyeball to the side close to the eyeball, and the discoloration area 1120 is set The second lens layer 1102 in the middle.

For the relevant details of the photoluminescent substance and the colorant, please refer to the above, and will not repeat them here.

<Twelfth Structural Example>

Please refer to FIG. 12 , which is a schematic cross-sectional view of a contact lens 1200 according to a twelfth structural embodiment of the present invention. The contact lens 1200 includes an optical zone (not shown in the figure) and a color-changing zone 1220. The color-changing zone 1220 includes at least one photoluminescent substance, and the color-changing zone 1220 further includes a colorant (the dots in FIG. 12 represent the photoluminescent substance mixed with the coloring material), wherein the color-changing region 1220 is a single-ring structure and is concentrically arranged with the optical region, and other relevant details of the color-changing region 1220 can be referred to above, and will not be repeated here.

As shown in Figure 12, the contact lens 1200 includes a first lens layer 1201, a second lens layer 1202, and a third lens layer 1203 from the side away from the eyeball to the side close to the eyeball in sequence, and the discoloration area 1220 is set The second lens layer 1202 in the middle.

For the relevant details of the photoluminescent substance and the colorant, please refer to the above, and will not repeat them here.

<Thirteenth Structural Embodiment>

Please refer to FIG. 13 , which is a schematic cross-sectional view of a contact lens 1300 according to a thirteenth structural embodiment of the present invention. The contact lens 1300 includes an optical zone (not shown in the figure) and a color-changing zone 1320. The color-changing zone 1320 includes at least one photoluminescent substance (the dots in FIG. 13 represent the photoluminescent substance), wherein the color-changing zone 1320 is a single ring The structure is arranged concentrically with the optical area, and the color-changing area 1320 further includes a coloring material, and other relevant details of the color-changing area 1320 can be referred to above, and will not be repeated here.

As shown in FIG. 13, the contact lens 1300 includes a first lens layer 1301, a second lens layer 1302, a third lens layer 1303 and a fourth lens layer from the side away from the eyeball to the side close to the eyeball. layer 1304 , wherein the discoloration area 1320 is disposed on the second lens layer 1302 and the third lens layer 1303 , the photoluminescent substance is located on the second lens layer 1302 , and the colorant is located on the third lens layer 1303 .

For the relevant details of the photoluminescent substance and the colorant, please refer to the above, and will not repeat them here.

[Photoluminescent substance]

The following will describe in detail the composition examples of the specific composition of the photoluminescent material of the contact lens of the present invention.

＜First ingredient example＞

式(I-1)。 在第一成分例中，光致發光物質的一側鏈含碳數量為NC，其可滿足下列條件：NC = 4。In the contact lens in the first composition example of the present invention, the photoluminescent substance of the contact lens may have a structure as shown in formula (I-1):

Formula (I-1). In the first component example, the number of carbons contained in the side chain of the photoluminescent substance is NC, which can satisfy the following condition: NC=4.

In the first component example, the photoluminescent material of the contact lens can be applied to the contact lenses of the aforementioned first to thirteenth structural embodiments, while the first to thirteenth structural embodiments For details about contact lenses, please refer to the previous article and will not repeat them here.

＜Second component example＞

式(I-2)。 在第二成分例中，光致發光物質的一側鏈含碳數量為NC，其可滿足下列條件：NC = 18。In the second component example of the present invention, the photoluminescent substance of the contact lens can have a structure as shown in formula (I-2):

Formula (I-2). In the second component example, the number of carbons contained in the side chain of the photoluminescent substance is NC, which can satisfy the following condition: NC=18.

In the second composition example, the photoluminescent substance of the contact lens can be applied to the contact lenses of the aforementioned first to thirteenth structural embodiments, while the first to thirteenth structural embodiments For details about contact lenses, please refer to the previous article and will not repeat them here.

＜Example of the third component＞

式(I-3)。 在第三成分例中，光致發光物質的一側鏈含碳數量為NC，其可滿足下列條件：NC = 16。In the third component example of the present invention, the photoluminescent substance of the contact lens can have a structure as shown in formula (I-3):

Formula (I-3). In the third component example, the number of carbons contained in the side chain of the photoluminescent material is NC, which can satisfy the following condition: NC = 16.

In the third composition example, the photoluminescent material of the contact lens can be applied to the contact lenses of the aforementioned first to thirteenth structural embodiments, while the first to thirteenth structural embodiments For details about contact lenses, please refer to the previous article and will not repeat them here.

＜Example of the fourth ingredient＞

式(II-1)。 在第四成分例中，二中括號框選處分別代表R¹ 與R² ，R¹ 與R² 係各自獨立為一醚氧基，其中n為正整數；較佳地，n的範圍可為1~18。In the fourth component example of the present invention, the photoluminescent substance of the contact lens may have a structure as shown in formula (II-1):

Formula (II-1). In the fourth component example, the double square brackets represent R ¹ and R ² respectively, and R ¹ and R ² are each independently an etheroxy group, wherein n is a positive integer; preferably, the range of n can be 1~18.

In the fourth composition example, the photoluminescent material of the contact lens can be applied to the contact lenses of the aforementioned first to thirteenth structural embodiments, while the first to thirteenth structural embodiments For details about contact lenses, please refer to the previous article and will not repeat them here.

＜Example of fifth component＞

式(II-2)。 在第五成分例中，-O-R代表側鏈，隱形眼鏡可更包含一金屬離子Cu²⁺ ，且二分子的光致發光物質與金屬離子Cu²⁺ 鍵結以形成一金屬離子錯合物。In the fifth component example of the present invention, the photoluminescent substance of the contact lens can have a structure as shown in formula (II-2):

Formula (II-2). In the fifth component example, -OR represents a side chain, and the contact lens may further include a metal ion Cu ²⁺ , and two molecules of the photoluminescent substance bond with the metal ion Cu ²⁺ to form a metal ion complex.

In the fifth composition example, the photoluminescent substance of the contact lens can be applied to the contact lenses of the aforementioned first to thirteenth structural embodiments, while the first to thirteenth structural embodiments For details about contact lenses, please refer to the previous article and will not repeat them here.

[Concentration of photoluminescent substance]

The concentration examples of different concentration ratios of the photoluminescent substance of the contact lens of the present invention and the comparative concentration examples not containing the photoluminescent substance will be described in detail below.

<Example of Comparative Concentration>

Comparative concentration examples are contact lenses that do not contain a photoluminescent substance. The contact lenses of the comparative concentration examples can be the contact lenses of the aforementioned first structural example to the thirteenth structural example, and for the details of the contact lenses of the first structural example to the thirteenth structural example, please refer to the above, in This will not be repeated.

Please refer to Figure 14 and Table 1 at the same time. Figure 14 shows the relationship between the transmittance, absorption value and wavelength of the comparative concentration example, and Table 1 is the transmittance and the specific wavelength of the comparative concentration example. absorbing data. In the comparative concentration example, WP is the weight percent of the photoluminescent substance in the contact lens, |T| is the transmittance of the color-changing region at a specific wavelength, A is the absorption value of the color-changing region at a specific wavelength, and T2838 is The average transmittance of the discoloration zone at a wavelength of 280 nm to 380 nm, T2840 is the average transmittance of the discoloration zone at a wavelength of 280 nm to 400 nm, T3040 is the average transmittance of the discoloration zone at a wavelength of 300 nm to 400 nm, T3848 T3850 is the average transmittance of the discoloration zone at a wavelength of 380 nm to 500 nm, T4050 is the average transmittance of the discoloration zone at a wavelength of 400 nm to 500 nm, T4055 is the average transmittance of the discoloration region at a wavelength of 400 nm to 550 nm, T4070 is the average transmittance of the discoloration region at a wavelength of 400 nm to 700 nm, T4565 is the average transmittance of the discoloration region at a wavelength of 450 nm to 650 nm , T5058 is the average transmittance of the color changing region at a wavelength of 500 nm to 580 nm, T5078 is the average transmittance of the color changing region at a wavelength of 500 nm to 780 nm, T5570 is the average transmittance of the color changing region at a wavelength of 550 nm to 700 nm T5878 is the average transmittance of the discoloration region at a wavelength of 580 nm to 780 nm, A2838 is the average absorption value of the discoloration region at a wavelength of 280 nm to 380 nm, and A2840 is the average absorption value of the discoloration region at a wavelength of 280 nm to 400 nm , A3040 is the average absorption value of the color changing region at a wavelength of 300 nm~400 nm, A3848 is the average absorption value of the color changing region at a wavelength of 380 nm~480 nm, A3850 is the average absorption value of the color changing region at a wavelength of 380 nm~500 nm, A4050 A4055 is the average absorption value of the discoloration region at a wavelength of 400 nm to 550 nm, A4070 is the average absorption value of the discoloration region at a wavelength of 400 nm to 700 nm, and A4565 is the discoloration region A5058 is the average absorption value of the discoloration region at the wavelength of 500 nm to 580 nm, A5078 is the average absorption value of the discoloration region at the wavelength of 500 nm to 780 nm, and A5570 is the average absorption value of the discoloration region at the wavelength of 500 nm to 780 nm. The average absorption value at a wavelength of 550 nm to 700 nm, and A5878 is the average absorption value at a wavelength of 580 nm to 780 nm in the discoloration region. The definition of the transmittance and absorption value can be calculated according to the needs of the wavelength range, such as the average transmittance between 290 nm ~ 400 nm can be defined as T2940, the average absorption value between 290 nm ~ 400 nm can be defined as A2940. Table I photoluminescent substance none WP (%) 0 wavelength(nm) |T| (%) A 280 6.45 1.19 290 0.03 3.52 300 0.03 3.52 310 0.03 3.52 320 0.15 2.82 330 0.01 4.00 340 1.06 1.97 350 0.39 2.41 360 1.33 1.88 370 15.79 0.80 380 57.84 0.24 390 85.32 0.07 400 93.61 0.03 410 95.18 0.02 420 95.57 0.02 430 95.98 0.02 440 95.14 0.02 450 95.08 0.02 460 95.45 0.02 470 95.39 0.02 480 95.11 0.02 490 94.80 0.02 500 94.86 0.02 510 95.02 0.02 520 94.92 0.02 530 94.82 0.02 540 94.90 0.02 550 94.58 0.02 560 94.42 0.02 570 94.29 0.03 580 93.65 0.03 590 93.79 0.03 600 93.72 0.03 610 93.53 0.03 620 93.92 0.03 630 93.17 0.03 640 93.22 0.03 650 93.83 0.03 660 94.73 0.02 670 95.17 0.02 680 95.51 0.02 690 95.30 0.02 700 95.45 0.02 710 95.84 0.02 720 95.57 0.02 730 95.52 0.02 740 95.75 0.02 750 95.79 0.02 760 95.87 0.02 770 95.81 0.02 780 95.90 0.02 calculate data T2838 (%) 7.67 T2840 (%) 21.30 T3040 (%) 23.23 T3848 (%) 90.88 T3850 (%) 91.49 T4050 (%) 95.11 T4055 (%) 95.03 T4070 (%) 94.65 T4565 (%) 94.40 T5058 (%) 94.61 T5078 (%) 94.79 T5570 (%) 94.27 T5878 (%) 94.81 A2838 2.35 A2840 2.00 A3040 1.93 A3848 0.05 A3850 0.04 A4050 0.02 A4055 0.02 A4070 0.02 A4565 0.03 A5058 0.02 A5078 0.02 A5570 0.03 A5878 0.02 Absorbance (A) = - LOG ₁₀ (Transmittance)

From the results in Figure 14 and Table 1, it can be seen that in the case where the color-changing region does not contain photoluminescent substances, the T3848 of the comparative concentration example is 90.88%, while the A3850 is 0.04.

<Example of the first concentration>

The first concentration example is a contact lens containing a photoluminescent substance, and the photoluminescent substance is curcumin. The contact lenses of the first concentration embodiment can be the contact lenses of the aforementioned first structure embodiment to the thirteenth structure embodiment, and for the details of the contact lenses of the first structure embodiment to the thirteenth structure embodiment, please refer to the above, I won't go into details here.

Please refer to Figure 15 and Table 2 at the same time. Figure 15 shows the relationship between the transmittance, absorption value and wavelength of the first concentration embodiment of the present invention, and Table 2 shows the specific wavelength of the first concentration embodiment The data of transmittance and absorption value. In the first concentration example, WP, |T|, A, T2838, T2840, T3040, T3848, T3850, T4050, T4055, T4070, T4565, T5058, T5078, T5570, T5878, A2838, A2840, A3040, A3848, For the parameter definition of A3850, A4050, A4055, A4070, A4565, A5058, A5078, A5570 and A5878, please refer to the comparative concentration example. Table II photoluminescent substance curcumin WP (%) 0.05 wavelength(nm) |T| (%) A 280 0.86 2.07 290 0.31 2.51 300 0.22 2.65 310 0.29 2.54 320 0.22 2.66 330 0.12 2.94 340 0.14 2.84 350 0.26 2.59 360 1.87 1.73 370 17.00 0.77 380 55.49 0.26 390 77.84 0.11 400 84.22 0.07 410 86.41 0.06 420 88.19 0.05 430 89.47 0.05 440 90.42 0.04 450 91.12 0.04 460 91.38 0.04 470 91.54 0.04 480 91.94 0.04 490 92.01 0.04 500 92.04 0.04 510 92.23 0.04 520 92.25 0.04 530 92.27 0.03 540 92.29 0.03 550 92.29 0.03 560 92.31 0.03 570 92.49 0.03 580 92.37 0.03 590 92.45 0.03 600 92.57 0.03 610 92.45 0.03 620 92.50 0.03 630 92.50 0.03 640 92.47 0.03 650 92.49 0.03 660 92.56 0.03 670 92.50 0.03 680 92.63 0.03 690 92.53 0.03 700 92.64 0.03 710 92.68 0.03 720 92.68 0.03 730 92.78 0.03 740 92.75 0.03 750 92.50 0.03 760 92.79 0.03 770 92.51 0.03 780 92.85 0.03 calculate data T2838 (%) 6.98 T2840 (%) 18.37 T3040 (%) 21.61 T3848 (%) 85.27 T3850 (%) 86.31 T4050 (%) 89.88 T4055 (%) 90.63 T4070 (%) 91.53 T4565 (%) 92.19 T5058 (%) 92.28 T5078 (%) 92.50 T5570 (%) 92.48 T5878 (%) 92.58 A2838 2.14 A2840 1.83 A3040 1.74 A3848 0.07 A3850 0.07 A4050 0.05 A4055 0.04 A4070 0.04 A4565 0.04 A5058 0.03 A5078 0.03 A5570 0.03 A5878 0.03 Absorbance (A) = - LOG ₁₀ (Transmittance)

<Second Concentration Example>

The second concentration example is a contact lens containing a photoluminescent substance, and the photoluminescent substance is curcumin. The contact lenses of the second concentration embodiment can be the contact lenses of the aforementioned first structure embodiment to the thirteenth structure embodiment, and for the details of the contact lenses of the first structure embodiment to the thirteenth structure embodiment, please refer to the above, I won't go into details here.

Please refer to Figure 16 and Table 3 at the same time. Figure 16 shows the relationship between the transmittance, absorption value and wavelength of the second concentration embodiment of the present invention, and Table 3 shows the specific wavelength of the second concentration embodiment The data of transmittance and absorption value. In the second concentration example, WP, |T|, A, T2838, T2840, T3040, T3848, T3850, T4050, T4055, T4070, T4565, T5058, T5078, T5570, T5878, A2838, A2840, A3040, A3848, For the parameter definition of A3850, A4050, A4055, A4070, A4565, A5058, A5078, A5570 and A5878, please refer to the comparative concentration example. Table three photoluminescent substance curcumin WP (%) 0.10 wavelength(nm) |T| (%) A 280 1.61 1.79 290 0.62 2.21 300 0.46 2.33 310 0.56 2.25 320 0.47 2.33 330 0.33 2.48 340 0.38 2.42 350 0.82 2.09 360 3.79 1.42 370 21.24 0.67 380 55.20 0.26 390 73.31 0.13 400 79.30 0.10 410 82.40 0.08 420 85.35 0.07 430 87.67 0.06 440 89.21 0.05 450 90.32 0.04 460 91.02 0.04 470 91.67 0.04 480 92.20 0.04 490 92.62 0.03 500 92.75 0.03 510 92.92 0.03 520 93.01 0.03 530 93.10 0.03 540 93.15 0.03 550 93.19 0.03 560 93.13 0.03 570 93.36 0.03 580 93.22 0.03 590 93.38 0.03 600 93.34 0.03 610 93.36 0.03 620 93.33 0.03 630 93.39 0.03 640 93.44 0.03 650 93.32 0.03 660 93.41 0.03 670 93.30 0.03 680 93.47 0.03 690 93.37 0.03 700 93.37 0.03 710 93.59 0.03 720 93.49 0.03 730 93.50 0.03 740 93.61 0.03 750 93.50 0.03 760 93.53 0.03 770 93.41 0.03 780 93.54 0.03 calculate data T2838 (%) 7.77 T2840 (%) 18.32 T3040 (%) 21.44 T3848 (%) 83.42 T3850 (%) 84.85 T4050 (%) 88.59 T4055 (%) 89.99 T4070 (%) 91.61 T4565 (%) 92.82 T5058 (%) 93.09 T5078 (%) 93.33 T5570 (%) 93.33 T5878 (%) 93.42 A2838 1.84 A2840 1.58 A3040 1.50 A3848 0.08 A3850 0.08 A4050 0.05 A4055 0.05 A4070 0.04 A4565 0.03 A5058 0.03 A5078 0.03 A5570 0.03 A5878 0.03 Absorbance (A) = - LOG ₁₀ (Transmittance)

<Third concentration example>

The third concentration example is a contact lens containing a photoluminescent substance, and the photoluminescent substance is curcumin. The contact lenses of the third concentration embodiment can be the contact lenses of the aforementioned first structure embodiment to the thirteenth structure embodiment, and for the details of the contact lenses of the first structure embodiment to the thirteenth structure embodiment, please refer to the above, I won't go into details here.

Please refer to Figure 17 and Table 4 at the same time. Figure 17 shows the relationship between the transmittance, absorption value and wavelength of the third concentration embodiment of the present invention, and Table 4 is the third concentration embodiment at a specific wavelength. Data on transmittance and absorbance values. In a third concentration example, WP, |T|, A, T2838, T2840, T3040, T3848, T3850, T4050, T4055, T4070, T4565, T5058, T5078, T5570, T5878, A2838, A2840, A3040, A3848, For the parameter definition of A3850, A4050, A4055, A4070, A4565, A5058, A5078, A5570 and A5878, please refer to the comparative concentration example. Table four photoluminescent substance curcumin WP (%) 0.20 wavelength(nm) |T| (%) A 280 0.62 2.21 290 0.29 2.54 300 0.22 2.67 310 0.24 2.61 320 0.18 2.76 330 0.14 2.87 340 0.13 2.87 350 0.25 2.60 360 1.36 1.87 370 11.62 0.93 380 37.88 0.42 390 54.20 0.27 400 60.31 0.22 410 63.72 0.20 420 67.16 0.17 430 70.39 0.15 440 73.54 0.13 450 76.40 0.12 460 79.09 0.10 470 82.89 0.08 480 86.56 0.06 490 89.29 0.05 500 90.87 0.04 510 91.94 0.04 520 92.27 0.03 530 92.64 0.03 540 92.86 0.03 550 92.92 0.03 560 92.99 0.03 570 93.19 0.03 580 93.17 0.03 590 93.29 0.03 600 93.31 0.03 610 93.28 0.03 620 93.30 0.03 630 93.23 0.03 640 93.35 0.03 650 93.38 0.03 660 93.32 0.03 670 93.29 0.03 680 93.59 0.03 690 93.47 0.03 700 93.47 0.03 710 93.51 0.03 720 93.57 0.03 730 93.46 0.03 740 93.61 0.03 750 93.33 0.03 760 93.60 0.03 770 93.48 0.03 780 93.56 0.03 calculate data T2838 (%) 4.81 T2840 (%) 12.88 T3040 (%) 15.14 T3848 (%) 68.38 T3850 (%) 71.71 T4050 (%) 76.38 T4055 (%) 81.43 T4070 (%) 87.18 T4565 (%) 90.49 T5058 (%) 92.54 T5078 (%) 93.15 T5570 (%) 93.28 T5878 (%) 93.41 A2838 2.21 A2840 1.91 A3040 1.83 A3848 0.17 A3850 0.16 A4050 0.12 A4055 0.09 A4070 0.06 A4565 0.04 A5058 0.03 A5078 0.03 A5570 0.03 A5878 0.03 Absorbance (A) = - LOG ₁₀ (Transmittance)

Please refer to Fig. 18 and Table 5 at the same time. Fig. 18 shows the relationship between the radiation intensity and wavelength of the third concentration embodiment of the present invention, and Table 5 is the light-induced radiation of the third concentration embodiment at a specific wavelength. Data on the radiation intensity of a luminescent substance. In the third concentration embodiment, CT is the center thickness of the contact lens, Em4050 is the average radiation intensity with a wavelength of 400 nm to 500 nm, Em4055 is the average radiation intensity with a wavelength of 400 nm to 550 nm, and Em4070 is the average radiation intensity with a wavelength of 400 nm to 700 nm Em4565 is the average radiation intensity of wavelength 450 nm~650 nm, Em5058 is the average radiation intensity of wavelength 500 nm~580 nm, Em5055 is the average radiation intensity of wavelength 500 nm~550 nm, Em5254 is the average radiation intensity of wavelength 520 nm~ The average radiation intensity at 540 nm, and Em5570 is the average radiation intensity at a wavelength of 550 nm to 700 nm. Table five, the third concentration embodiment wavelength(nm) Radiation intensity (AU) 400 10.71 410 17.57 420 22.1 430 23.8 440 30.66 450 30.72 460 31.93 470 36.88 480 42.74 490 54.49 500 67.38 510 79.16 520 83.89 530 84.32 540 74.85 550 63.8 560 52.15 570 40.36 580 28.13 590 19.61 600 14.31 610 10.24 620 8.36 630 6.331 640 5.177 650 4.052 660 4.375 670 3.615 680 3.901 690 3.842 700 4.209 calculate data CT (mm) 0.084 Em4050 (AU) 33.54 Em4055 (AU) 47.19 Em4070 (AU) 31.09 Em4565 (AU) 39.95 Em5058 (AU) 63.78 Em5055 (AU) 75.57 Em5254 (AU) 81.02 Em5570 (AU) 17.03

From the data in Figure 18 and Table 5, in the third concentration example, when the maximum radiation intensity is 84.32, the wavelength of the maximum radiation intensity of the photoluminescent substance is WEmMx = 530 mn.

<Fourth Concentration Example>

The fourth concentration example is a contact lens containing a photoluminescent substance, and the photoluminescent substance is curcumin. The contact lens of the fourth concentration embodiment can be the contact lens of the aforementioned first structure embodiment to the thirteenth structure embodiment, and for the details of the contact lenses of the first structure embodiment to the thirteenth structure embodiment, please refer to the above, I won't go into details here.

Please refer to Figure 19 and Table 6 at the same time. Figure 19 shows the relationship between the transmittance, absorption value and wavelength of the fourth concentration embodiment of the present invention, and Table 6 shows the fourth concentration embodiment at a specific wavelength. The data of transmittance and absorption value. In the fourth concentration example, WP, |T|, A, T2838, T2840, T3040, T3848, T3850, T4050, T4055, T4070, T4565, T5058, T5078, T5570, T5878, A2838, A2840, A3040, A3848, For the parameter definition of A3850, A4050, A4055, A4070, A4565, A5058, A5078, A5570 and A5878, please refer to the comparative concentration example. Table six photoluminescent substance curcumin WP (%) 0.50 wavelength(nm) |T| (%) A 280 0.65 2.19 290 0.27 2.57 300 0.21 2.68 310 0.24 2.63 320 0.19 2.72 330 0.13 2.89 340 0.15 2.84 350 0.26 2.58 360 1.02 1.99 370 6.20 1.21 380 17.08 0.77 390 23.12 0.64 400 25.11 0.60 410 26.39 0.58 420 28.04 0.55 430 30.84 0.51 440 34.59 0.46 450 39.13 0.41 460 44.89 0.35 470 53.30 0.27 480 63.93 0.19 490 73.80 0.13 500 80.47 0.09 510 84.50 0.07 520 86.83 0.06 530 88.48 0.05 540 89.60 0.05 550 90.31 0.04 560 90.72 0.04 570 91.18 0.04 580 91.24 0.04 590 91.42 0.04 600 91.66 0.04 610 91.68 0.04 620 91.81 0.04 630 91.98 0.04 640 92.06 0.04 650 92.15 0.04 660 92.36 0.03 670 92.42 0.03 680 92.49 0.03 690 92.48 0.03 700 92.57 0.03 710 92.69 0.03 720 92.70 0.03 730 92.75 0.03 740 92.85 0.03 750 92.63 0.03 760 92.84 0.03 770 92.81 0.03 780 92.91 0.03 calculate data T2838 (%) 2.40 T2840 (%) 5.74 T3040 (%) 6.70 T3848 (%) 35.13 T3850 (%) 41.59 T4050 (%) 45.50 T4055 (%) 58.76 T4070 (%) 74.79 T4565 (%) 81.48 T5058 (%) 88.15 T5078 (%) 91.05 T5570 (%) 91.78 T5878 (%) 92.31 A2838 2.28 A2840 2.02 A3040 1.96 A3848 0.48 A3850 0.43 A4050 0.38 A4055 0.28 A4070 0.16 A4565 0.10 A5058 0.06 A5078 0.04 A5570 0.04 A5878 0.03 Absorbance (A) = - LOG ₁₀ (Transmittance)

It should be noted here that although the structural embodiments, composition examples and concentration embodiments of the present invention have been disclosed above, the technical features of each embodiment can be combined and configured arbitrarily to achieve the corresponding effects. The structural embodiments of the present invention , Composition examples and concentration examples are only used to illustrate the efficacy of the contact lens of the present invention when it contains photoluminescent substances, and are hereby described first.

Although the present invention has been disclosed above in terms of implementation, it is not intended to limit the present invention. Anyone skilled in the art can make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the protection of the present invention The scope shall be defined by the scope of the appended patent application.

100,200,300,400,500,600,700,800,900,1000,1100,1200,1300: contact lens 110,210,310,410,510,610,710,810: optical area 120,220,320,420,520,620,720,820,920,1020,1120,1220,1320: color changing area 630:Pattern color change area 901, 1001, 1101, 1201, 1301: first lens layer 902, 1002, 1102, 1202, 1302: second lens layer 1003, 1103, 1203, 1303: the third lens layer 1304: The fourth lens layer WEmMx: the wavelength at which the photoluminescent substance has the maximum emission intensity |T|: Transmittance of the color-changing region at a specific wavelength T4070: The average transmittance of the color-changing region at a wavelength of 400 nm to 700 nm T3848: The average transmittance of the color-changing region at a wavelength of 380 nm~480 nm T2838: The average transmittance of the color-changing region at a wavelength of 280 nm~380 nm T2840: The average transmittance of the color-changing region at a wavelength of 280 nm to 400 nm T3040: The average transmittance of the color-changing region at a wavelength of 300 nm~400 nm T3850: The average transmittance of the color-changing region at a wavelength of 380 nm to 500 nm T4050: The average transmittance of the color-changing region at a wavelength of 400 nm~500 nm T4055: The average transmittance of the color-changing region at a wavelength of 400 nm to 550 nm T4565: The average transmittance of the color-changing region at a wavelength of 450 nm to 650 nm T5058: The average transmittance of the color-changing region at a wavelength of 500 nm~580 nm T5078: The average transmittance of the color-changing region at a wavelength of 500 nm~780 nm T5570: The average transmittance of the color-changing region at a wavelength of 550 nm to 700 nm T5878: The average transmittance of the color-changing region at a wavelength of 580 nm~780 nm A: The absorption value of the color-changing area at a specific wavelength A3850: The average absorption value of the color-changing region at a wavelength of 380 nm to 500 nm A2838: The average absorption value of the color-changing region at a wavelength of 280 nm~380 nm A2840: The average absorption value of the color-changing region at a wavelength of 280 nm to 400 nm A3040: The average absorption value of the color-changing region at a wavelength of 300 nm to 400 nm A3848: The average absorption value of the color-changing region at a wavelength of 380 nm~480 nm A4050: The average absorption value of the color-changing region at a wavelength of 400 nm~500 nm A4055: The average absorption value of the color-changing region at a wavelength of 400 nm to 550 nm A4070: The average absorption value of the color-changing region at a wavelength of 400 nm to 700 nm A4565: The average absorption value of the color-changing region at a wavelength of 450 nm to 650 nm A5058: The average absorption value of the color-changing region at a wavelength of 500 nm to 580 nm A5078: The average absorption value of the color-changing region at a wavelength of 500 nm to 780 nm A5570: The average absorption value of the color-changing region at a wavelength of 550 nm to 700 nm A5878: The average absorption value of the color-changing region at a wavelength of 580 nm~780 nm CT: Central thickness of contact lens Em4050: Average radiation intensity at wavelength 400 nm~500 nm Em4055: Average radiation intensity at wavelength 400 nm~550 nm Em4070: Average radiation intensity at wavelength 400 nm~700 nm Em4565: Average radiation intensity at wavelength 450 nm~650 nm Em5058: Average radiation intensity at wavelength 500 nm~580 nm Em5055: Average radiation intensity at wavelength 500 nm~550 nm Em5254: Average radiation intensity at wavelength 520 nm~540 nm Em5570: Average radiation intensity at wavelength 550 nm~700 nm NC: the number of carbons in the side chain of the photoluminescent substance WP: the weight percentage of photoluminescent substance in contact lens AC: total area of discoloration zone AL: total area of the contact lens D: The diameter of the contact lens DPmax: the maximum diameter of the discoloration zone DPmin: the minimum diameter of the discoloration zone

In order to make the above and other objects, features, advantages and embodiments of the present invention more obvious and understandable, the accompanying drawings are described as follows: Figure 1 is a schematic diagram of a contact lens according to the first structural embodiment of the present invention; Figure 2 is a schematic diagram of a contact lens according to the second structural embodiment of the present invention; Figure 3 is a schematic diagram of a contact lens according to a third structural embodiment of the present invention; Figure 4 is a schematic diagram of a contact lens according to a fourth structural embodiment of the present invention; Fig. 5 is a schematic diagram of a contact lens according to a fifth structural embodiment of the present invention; Fig. 6 is a schematic diagram of a contact lens according to the sixth structural embodiment of the present invention; Fig. 7 is a schematic diagram of a contact lens according to a seventh structural embodiment of the present invention; Fig. 8 is a schematic diagram showing a contact lens according to the eighth structural embodiment of the present invention; Figure 9 is a schematic cross-sectional view of a contact lens according to a ninth structural embodiment of the present invention; Figure 10 is a schematic cross-sectional view of a contact lens according to a tenth structural embodiment of the present invention; Figure 11 is a schematic cross-sectional view of a contact lens according to an eleventh structural embodiment of the present invention; Fig. 12 is a schematic cross-sectional view of a contact lens according to a twelfth structural embodiment of the present invention; Fig. 13 is a schematic cross-sectional view of a contact lens according to a thirteenth structural embodiment of the present invention; Figure 14 is a graph showing the relationship between the transmittance, the absorption value and the wavelength of the comparative concentration examples; Figure 15 is a graph showing the relationship between transmittance, absorption value and wavelength of the first concentration embodiment of the present invention; Figure 16 is a diagram showing the relationship between the transmittance, absorption value and wavelength of the second concentration embodiment of the present invention; Figure 17 is a graph showing the relationship between the transmittance, absorption value and wavelength of the third concentration embodiment of the present invention; Figure 18 is a diagram showing the relationship between radiation intensity and wavelength of the third concentration embodiment of the present invention; and Fig. 19 is a graph showing the relationship between transmittance, absorption value and wavelength of the fourth concentration embodiment of the present invention.

100: contact lenses

110: optical zone

120: color changing area

D: The diameter of the contact lens

DPmax: the maximum diameter of the discoloration zone

DPmin: the minimum diameter of the discoloration zone

Claims (11)

A contact lens comprising: At least one color-changing region, wherein the color-changing region comprises at least one photoluminescent substance, and the photoluminescent substance is curcumin or a curcumin derivative; Wherein, the contact lens comprises at least two lens layers; Wherein, the average transmittance of the discoloration region at a wavelength of 380 nm to 480 nm is T3848, the average transmittance of the discoloration region at a wavelength of 400 nm to 700 nm is T4070, and the weight of the photoluminescent substance in the contact lens The percentage is WP, which satisfies the following conditions: T3848 ≤ 85%; 85% ≤ T4070; and 0.01% ≤ WP. The contact lens as claimed in item 1, wherein the photoluminescent substance has a structure as shown in formula (I):

Formula (I); Wherein the side chain of the photoluminescent substance is -XR ¹ or -XR ² or -XR ³ , at least one of R ¹ or R ² or R ³ is a saturated carbon chain or an unsaturated carbon chain, and X is oxygen. The contact lens according to claim 1, wherein the photoluminescent substance has a structure as shown in formula (II):

Formula (II); Wherein the side chain of the photoluminescent substance is -XR ¹ or -XR ² , at least one of R ¹ or R ² is a saturated carbon chain or an unsaturated carbon chain, and X is oxygen. The contact lens as described in Claim 1, wherein the weight percentage of the photoluminescent substance in the contact lens is WP, which meets the following conditions: 0.05% ≤ WP. The contact lens as described in claim 4, wherein the weight percentage of the photoluminescent substance in the contact lens is WP, which meets the following conditions: 0.1% ≤ WP. The contact lens as described in claim 5, wherein the weight percentage of the photoluminescent substance in the contact lens is WP, which meets the following conditions: 0.2% ≤ WP ≤ 1.0%. The contact lens as described in Claim 1, wherein the average transmittance of the color-changing region at a wavelength of 380 nm to 480 nm is T3848, which meets the following conditions: T3848 ≤ 68.38%. The contact lens as described in claim 7, wherein the average transmittance of the color-changing region at a wavelength of 380 nm to 500 nm is T3850, which meets the following conditions: T3850 ≤ 71.71%. The contact lens as described in claim 8, wherein the total area of the discoloration zone is AC, the total area of the contact lens is AL, and it satisfies the following conditions: 0.5 < AC/AL ≤ 1.0. The contact lens according to claim 9, wherein at least one of the discoloration regions is a pattern. A contact lens product comprising: The contact lens as described in Claim 1; and - dark packaging; Among them, the contact lens product is daily disposable.

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