TWI771838B - Wound multiple sensing method and wound multiple sensing system - Google Patents

Wound multiple sensing method and wound multiple sensing system Download PDF

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TWI771838B
TWI771838B TW109145690A TW109145690A TWI771838B TW I771838 B TWI771838 B TW I771838B TW 109145690 A TW109145690 A TW 109145690A TW 109145690 A TW109145690 A TW 109145690A TW I771838 B TWI771838 B TW I771838B
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wound
expected
data sequence
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case
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TW202226267A (en
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蔣岳珉
劉建宏
洪上智
黎和欣
陳建任
謝閔易
李仁貴
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財團法人工業技術研究院
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Abstract

The present invention discloses a wound multiple sensing method, including: calculating a similarity between the current data sequence and each of the case data sequences for each of the reference cases; selecting the case data sequence which has the highest similarity with the current data sequence, from the case data sequences for each of the reference cases, to be a similar case data sequence in each of the reference cases, wherein the similar case data sequence is corresponding to a similar case treatment; performing a multiple regression analysis using the similar case data sequences and the similar case treatments to calculate a fitness function, wherein the dependent variable of the fitness function is a wound change; performing a parameter optimization algorithm using the current data sequence and the fitness function to calculate a best treatment maximizing the wound change, and an expected wound change value corresponding to the best treatment.

Description

傷口多重感測方法及系統Wound multiple sensing method and system

本發明涉及一種感測方法及系統,特別涉及一種傷口多重感測的方法及系統。The present invention relates to a sensing method and system, in particular to a wound multiple sensing method and system.

根據統計,全球老年人口之動靜脈潰瘍及壓瘡盛行率為6%,全球糖尿病盛行率為8.8%。這些病患經常會衍生超過三個月難以癒合的慢性傷口,在在顯示出遠距傷口照護的需求係很大的。According to statistics, the global prevalence of arteriovenous ulcers and pressure ulcers in the elderly population is 6%, and the global prevalence of diabetes is 8.8%. These patients often develop chronic wounds that are difficult to heal for more than three months, showing a great need for remote wound care.

執行傷口照護的一般護理師或照護師,通常僅根據傷口當下狀況進行判斷及處置,例如最基本的傷口清潔消毒。然而,這種「頭痛醫頭、腳痛醫腳」的簡易護理處置,經常使傷口長時間停留在發炎期或增生期,延誤傷口復原。更甚者,傷口因錯誤判斷而導致無法癒合,增加了感染或壞死的風險,最終導致敗血症或截肢的結果。General nurses or nurses who perform wound care usually only make judgments and treatments based on the current condition of the wound, such as the most basic wound cleaning and disinfection. However, this kind of simple nursing and treatment of "headache, foot pain, foot pain" often makes the wound stay in the inflammatory or proliferative stage for a long time, delaying the recovery of the wound. What's more, wounds fail to heal due to misjudgment, increasing the risk of infection or necrosis, which can ultimately result in sepsis or amputation.

此外,由於照護建議(guideline)的複雜與多面向的特性,一般護理師或照護師難以做出周延的判斷。教條式的指引在面對複雜狀況時,常有優先序不明甚至矛盾衝突的狀況發生,因而更增加護理師或照護師處理病患傷口的難度。此外,由於敷料的產品種類繁多,在選用上經常存在困擾,因而需採納專業人士,例如傷口造口護理師(Certificated Wound, Ostomy and Continence Nurse; CWOCN)的經驗,並且需要更多對於傷口病況的觀察與建議。In addition, due to the complex and multi-faceted nature of care recommendations (guidelines), it is difficult for general nurses or caregivers to make extensive judgments. In the face of complex situations, dogmatic guidance often leads to unclear or even conflicting situations, which makes it even more difficult for nurses or caregivers to deal with patient wounds. In addition, due to the wide variety of dressing products, there are often difficulties in selection, so the experience of professionals, such as Certified Wound, Ostomy and Continence Nurse (CWOCN), needs to be adopted, and more knowledge of wound conditions is required. Observations and recommendations.

因此,需要有一種傷口多重感測方法及系統,能推估傷口癒合的進度,及提供照護處置上的建議。Therefore, there is a need for a wound multi-sensing method and system that can estimate the progress of wound healing and provide recommendations on care and treatment.

本發明之實施例提供一種傷口多重感測方法,包含:讀取複數個參考案例,其中每個參考案例包含複數個案例資料序列;接收傷口之當前傷口表徵,其中當前傷口表徵包含多項傷口觀察數據;基於傷口之多項傷口觀察數據,建立當前資料序列;計算當前資料序列與每個參考案例的每個案例資料序列之相似度;從每個參考案例的案例資料序列中,選取與當前資料序列之相似度最高的案例資料序列,作為每個參考案例中的相似案例資料序列,其中相似案例資料序列對應於相似案例處置方針;使用相似案例資料序列及相似案例處置方針執行多元回歸分析(multiple regression analysis),以計算出適應度函數(fitness function),其中適應度函數之應變數為傷口變化;使用當前資料序列與適應度函數執行參數最佳化演算法,以計算出使傷口變化最大化的最佳處置方針及對應最佳處置方針的預期傷口變化值。An embodiment of the present invention provides a wound multi-sensing method, comprising: reading a plurality of reference cases, wherein each reference case includes a plurality of case data sequences; receiving a current wound representation of the wound, wherein the current wound representation includes a plurality of wound observation data ; Based on multiple wound observation data of the wound, establish the current data sequence; Calculate the similarity between the current data sequence and each case data sequence of each reference case; The case data sequence with the highest similarity is used as the similar case data sequence in each reference case, where the similar case data sequence corresponds to the similar case treatment policy; multiple regression analysis is performed using the similar case data sequence and the similar case treatment policy ), to calculate the fitness function, wherein the strain number of the fitness function is the wound change; use the current data sequence and the fitness function to perform a parameter optimization algorithm to calculate the maximum wound change that maximizes The optimal treatment policy and the expected wound change value corresponding to the optimal treatment policy.

在某些實施例中,上述方法更包含:第一操作:使用當前資料序列及預期傷口變化值估算預期資料序列,其中預期資料序列包含至少一尺寸參數;第二操作:使用預期資料序列及適應度函數執行參數最佳化演算法,以計算出使傷口變化最大的下一最佳處置方針及對應下一最佳處置方針的下一預期傷口變化值,再使用預期資料序列及下一預期傷口變化值,估算下一預期資料序列;其中,下一預期資料序列被處理器用作為新的預期資料序列以重複執行第二操作,直到計算出下一預期資料序列中的該至少一尺寸參數皆為0。In some embodiments, the above method further includes: first operation: using the current data series and the expected wound change value to estimate the expected data series, wherein the expected data series includes at least one size parameter; the second operation: using the expected data series and adapting The degree function performs a parameter optimization algorithm to calculate the next best treatment policy that maximizes the wound change and the next expected wound change value corresponding to the next best treatment policy, and then uses the expected data sequence and the next expected wound The change value is used to estimate the next expected data sequence; wherein, the next expected data sequence is used by the processor as a new expected data sequence to repeat the second operation until it is calculated that the at least one size parameter in the next expected data sequence is all 0.

在某些實施例中,該至少一尺寸參數為預期傷口長度、預期傷口寬度及預期傷口深度。In certain embodiments, the at least one dimension parameter is expected wound length, expected wound width, and expected wound depth.

在某些實施例中,上述方法更包含:累計第二操作被執行的次數,直到計算出下一預期資料序列中的該至少一尺寸參數皆為0;將第二操作被執行的次數加1,再乘以被感測的週期,以得出預期傷口癒合天數。In some embodiments, the above method further includes: accumulating the number of times the second operation is performed until the at least one size parameter in the next expected data sequence is calculated to be 0; adding 1 to the number of times the second operation is performed , multiplied by the sensed period to get the expected wound healing days.

在某些實施例中,傷口變化包含下列三個維度:傷口長度變化、傷口寬度變化及傷口深度變化;及其中使傷口變化最大化包含:使傷口體積變化最大化;及其中預期傷口變化值包含預期傷口長度變化值、預期傷口寬度變化值與預期傷口深度變化值。In certain embodiments, the wound change comprises the following three dimensions: wound length change, wound width change, and wound depth change; and wherein maximizing wound change comprises: maximizing wound volume change; and wherein the expected wound change value comprises Expected Wound Length Change, Expected Wound Width Change, and Expected Wound Depth Change.

在某些實施例中,上述方法更包含:使用傷口機中的色彩感測器以取得多項傷口觀察數據中的傷口組織數據;使用傷口機中的深度感測器以取得多項傷口觀察數據中的傷口範圍表面積數據;使用傷口機中的溫度感測器以取得多項傷口觀察數據中的傷口溫度數據。In some embodiments, the above-mentioned method further comprises: using a color sensor in the wound machine to obtain wound tissue data among the plurality of wound observation data; using a depth sensor in the wound machine to obtain a plurality of wound observation data Wound area surface area data; use the temperature sensor in the wound machine to obtain wound temperature data from multiple wound observations.

在某些實施例中,每個參考案例更包含表徵記錄、質性問卷記錄及照護處置記錄;其中案例資料序列係基於表徵記錄所建立;及其中相似案例處置方針係基於質性問卷記錄及照護處置記錄所建立。In some embodiments, each reference case further includes a characterization record, a qualitative questionnaire record, and a care disposition record; wherein the case data sequence is established based on the characterization record; and wherein the similar case disposition policy is based on the qualitative questionnaire record and care treatment record Disposition records are established.

本發明之實施例提供一種傷口多重感測系統,該系統包含處理器,用以執行:讀取複數個參考案例,其中每個參考案例包含複數個案例資料序列;接收傷口之當前傷口表徵,其中當前傷口表徵包含多項傷口觀察數據;基於傷口之多項傷口觀察數據,建立當前資料序列;計算當前資料序列與每個參考案例的每個案例資料序列之相似度;從每個參考案例的案例資料序列中,選取與當前資料序列之相似度最高的案例資料序列,作為每個參考案例中的相似案例資料序列,其中相似案例資料序列對應於相似案例處置方針;使用相似案例資料序列及相似案例處置方針執行多元回歸分析,以計算出適應度函數,其中適應度函數之應變數為傷口變化;使用當前資料序列與適應度函數執行參數最佳化演算法,以計算出使傷口變化最大化的最佳處置方針及對應最佳處置方針的預期傷口變化值。Embodiments of the present invention provide a wound multi-sensing system, the system including a processor for performing: reading a plurality of reference cases, wherein each reference case includes a plurality of case data sequences; receiving a current wound representation of the wound, wherein The current wound representation includes multiple wound observation data; based on the multiple wound observation data of the wound, the current data sequence is established; the similarity between the current data sequence and each case data sequence of each reference case is calculated; from the case data sequence of each reference case Select the case data sequence with the highest similarity with the current data sequence as the similar case data sequence in each reference case, where the similar case data sequence corresponds to the similar case handling policy; use the similar case data sequence and the similar case handling policy Perform a multiple regression analysis to calculate a fitness function, where the strain number of the fitness function is the wound change; use the current data sequence and the fitness function to perform a parameter optimization algorithm to calculate the optimal wound to maximize the change. The treatment policy and the expected wound change value corresponding to the optimal treatment policy.

在某些實施例中,該處理器更執行:第一操作:使用當前資料序列及預期傷口變化值估算預期資料序列,其中預期資料序列包含至少一尺寸參數;第二操作:使用預期資料序列及適應度函數執行參數最佳化演算法,以計算出使傷口變化最大的下一最佳處置方針及對應下一最佳處置方針的下一預期傷口變化值,再使用預期資料序列及下一預期傷口變化值,估算下一預期資料序列;其中,下一預期資料序列被用作為新的預期資料序列以重複執行第二操作,直到計算出下一預期資料序列中的該至少一尺寸參數皆為0。In some embodiments, the processor further performs: a first operation: using the current data series and the expected wound change value to estimate an expected data series, wherein the expected data series includes at least one size parameter; the second operation: using the expected data series and The fitness function performs a parameter optimization algorithm to calculate the next best treatment policy that maximizes the wound change and the next expected wound change value corresponding to the next best treatment policy, and then uses the expected data sequence and the next expected The wound change value is used to estimate the next expected data sequence; wherein, the next expected data sequence is used as a new expected data sequence to repeat the second operation until the at least one size parameter in the next expected data sequence is calculated to be 0.

在某些實施例中,該處理器更執行:累計第二操作被執行的次數,直到計算出下一預期資料序列中的該至少一尺寸參數皆為0;將該第二操作被執行的次數加1,再乘以被感測的週期,以得出預期傷口癒合天數。In some embodiments, the processor further executes: accumulating the number of times the second operation is performed until it is calculated that the at least one size parameter in the next expected data sequence is all 0; the number of times the second operation is performed Add 1 and multiply by the period sensed to get the expected wound healing days.

在某些實施例中,該系統更包含傷口機,傷口機包含:色彩感測器,用以取得多項傷口觀察數據中的傷口組織數據;深度感測器,用以取得多項傷口觀察數據中的傷口範圍表面積數據;溫度感測器,用以取得多項傷口觀察數據中的傷口溫度數據。In some embodiments, the system further includes a wound machine, and the wound machine includes: a color sensor for acquiring wound tissue data in a plurality of wound observation data; a depth sensor for acquiring a plurality of wound observation data in Wound area surface area data; temperature sensor, used to obtain wound temperature data in multiple wound observation data.

在某些實施例中,多項傷口觀察數據包含傷口組織數據、傷口範圍表面積數據及傷口溫度數據,且該系統更包含傷口機,傷口機包含:色彩感測器,用以取得傷口組織數據;深度感測器,用以取得傷口範圍表面積數據;溫度感測器,用以取得傷口溫度數據。In some embodiments, the plurality of wound observation data includes wound tissue data, wound area surface area data and wound temperature data, and the system further includes a wound machine, the wound machine including: a color sensor for obtaining wound tissue data; depth The sensor is used to obtain the surface area data of the wound area; the temperature sensor is used to obtain the wound temperature data.

本發明所提供的傷口多重感測方法及傷口多重感測系統,能藉由參考過往累積的相似案例,基於當前傷口的病況推估傷口癒合的進度,並提供照護處置上的建議。The wound multi-sensing method and wound multi-sensing system provided by the present invention can estimate the progress of wound healing based on the current condition of the wound by referring to similar cases accumulated in the past, and provide suggestions on care and treatment.

本發明所提供的傷口多重感測方法,係將病患傷口當前的病況與多個參考案例進行比對以篩選出多個相似案例,然後再基於該等相似案例的處置方針及傷口癒合的病程進展,推估傷口癒合的進度,及提供照護處置上的建議。The wound multi-sensing method provided by the present invention compares the current condition of the patient's wound with a plurality of reference cases to screen out a plurality of similar cases, and then based on the treatment policy of the similar cases and the course of wound healing progress, estimate the progress of wound healing, and provide advice on care and management.

根據本發明之實施例,每個上述參考案例可包含複數次的評估結果,其次數係取決於從第一次傷口被感測時起算,至傷口完全癒合時的時距(time interval),以及在這段期間內,傷口被感測的週期。舉例來說,以第一次傷口被感測時作為第1天,在第18天時傷口完全癒合,若在這18天內傷口被感測的週期為一天一次,則該參考案例會有18筆評估結果;若在這18天內傷口被感測的週期為三天一次,則該參考案例會有6筆評估結果。每一筆評估結果,又可包含表徵記錄、質性問卷記錄及照護處置記錄等三部分。According to an embodiment of the present invention, each of the above reference cases may include a plurality of evaluation results, the number of which depends on the time interval from when the first wound is sensed to when the wound is fully healed, and The period during which the wound is sensed. For example, take the first day when the wound is sensed as the first day, and the wound is completely healed on the 18th day. If the wound is sensed once a day during the 18 days, the reference case will have 18 Pen assessment results; if the wound is sensed once every three days within the 18 days, the reference case will have 6 assessment results. Each evaluation result can also include three parts: characteristic records, qualitative questionnaire records, and nursing treatment records.

上述表徵記錄,可包含例如傷口位置(例如背部、腳踝、手腕…等)、傷口長度、傷口寬度、傷口深度、傷口範圍表面積、滲出液量、滲出液性質、滲出液顏色、傷口溫度、傷口組織...等多項傷口觀察數據。在某些實施例中,可運用一傷口機來對病患的傷口取得表徵記錄中的多項傷口觀察數據。舉例來說,可運用傷口機中的色彩感測器取得傷口組織數據、可運用傷口機中的深度感測器取得傷口範圍表面積數據,以及可運用傷口機中的溫度感測器取得傷口溫度數據。The above characterization records may include, for example, wound location (e.g. back, ankle, wrist, etc.), wound length, wound width, wound depth, wound extent surface area, amount of exudate, nature of exudate, color of exudate, wound temperature, wound tissue ...and many other wound observation data. In some embodiments, a wound machine may be used to obtain multiple wound observations in a characterization record of a patient's wound. For example, the color sensor in the wound machine can be used to obtain wound tissue data, the depth sensor in the wound machine can be used to obtain wound area surface area data, and the temperature sensor in the wound machine can be used to obtain wound temperature data .

上述質性問卷記錄,可包含例如臥床環境(例如床單被褥的整理頻率及方式)、翻身技術(例如翻身的頻率及方式)、傷口護理(例如更換敷料的頻率及方式)及生理觀察(例如傷口狀況的肉眼評估、是否有發燒或畏寒症狀,及其他生理狀況的評估)等。上述處置記錄,則可包含例如敷料類型(例如紗布、矽膠、泡棉…等)、衛教對象(例如看護或家人)及衛教內容(例如床單被褥整理技術、傷口護理技術、翻身技術…等)等。The above-mentioned qualitative questionnaire records may include, for example, the bed resting environment (such as the frequency and method of making sheets and bedding), turning techniques (such as the frequency and method of turning over), wound care (such as the frequency and method of changing dressings), and physiological observations (such as wound Visual assessment of the condition, presence or absence of symptoms of fever or chills, and assessment of other physiological conditions), etc. The above-mentioned treatment records may include, for example, the type of dressing (such as gauze, silicone, foam, etc.), the object of health education (such as nursing or family members), and the content of health education (such as bedding and bedding techniques, wound care techniques, turning over techniques, etc. )Wait.

在某些實施例中,質性問卷紀錄及處置記錄,係由照護者或病患基於自身對於照護過程實際的體驗、認知與感受所填寫的。In some embodiments, the qualitative questionnaire record and treatment record are filled out by the caregiver or the patient based on their actual experience, cognition and feeling of the care process.

第1圖係根據本發明之實施例所繪示的方法100之流程圖。如第1圖所示,方法100包含操作101-107。於操作101,讀取複數個參考案例,其中每個參考案例包含複數個案例資料序列。然後,方法100進入操作102。FIG. 1 is a flowchart of a method 100 according to an embodiment of the present invention. As shown in FIG. 1, method 100 includes operations 101-107. In operation 101, a plurality of reference cases are read, wherein each reference case includes a plurality of case data sequences. The method 100 then proceeds to operation 102 .

根據本發明之實施例,如前所述,於操作101所讀取的參考案例的個數,係取決於從第一次傷口被感測時起算,至傷口完全癒合時的時距,以及在這段期間內傷口被感測的週期。每個參考案例所包含的複數個案例資料序列,係基於每次所感測到的表徵記錄之多項傷口觀察數據所建立。According to an embodiment of the present invention, as described above, the number of reference cases read in operation 101 depends on the time interval from when the wound is sensed for the first time to when the wound is fully healed, and when The period during which the wound is sensed. The multiple case data sequences included in each reference case are established based on multiple wound observation data recorded for each sensed characterization.

第2圖係根據本發明之實施例所提供的參考案例200之範例。如第2圖所示,參考案例200包含複數個案例資料序列,例如案例資料序列201、案例資料序列202、案例資料序列203及案例資料序列204。在本揭露的範例中,係假設從第一次傷口被感測時(即第2圖中的「第1天」)起算,至傷口完全癒合時(即第2圖中的「第N天」)的這段期間內,傷口被感測的週期為三天一次。案例資料序列201、案例資料序列202、案例資料序列203與案例資料序列204,分別係基於第1天、第4天、第7天與第N天所感測到的表徵記錄之多項傷口觀察數據所建立。舉例來說,案例資料序列201之{2.0, 3.0, 0.5, 50, 32, …}可代表第1天所感測到的傷口長度為2.0、傷口寬度為3.0、傷口深度為0.5、滲出液量為50、傷口溫度為32…等;案例資料序列202之{3.0, 2.0, 0.4, 25, 31, …},可代表第4天所感測到的傷口長度為3.0、傷口寬度為2.0、傷口深度為0.4、滲出液量為25、傷口溫度為31…等;案例資料序列203之{2.5, 1.5, 0.3, 30, 31, …}可代表第7天所感測到的傷口長度為2.5、傷口寬度為1.5、傷口深度為0.3、滲出液量為30、傷口溫度為31…等;案例資料序列201內的所有數據為0,則代表第N天感測到傷口已完全癒合。FIG. 2 is an example of a reference case 200 provided according to an embodiment of the present invention. As shown in FIG. 2 , the reference case 200 includes a plurality of case data sequences, such as a case data sequence 201 , a case data sequence 202 , a case data sequence 203 , and a case data sequence 204 . In the example of the present disclosure, it is assumed that the time from when the wound is sensed for the first time (ie, "Day 1" in Figure 2) to the time when the wound is completely healed (ie, "Day N" in Figure 2) ), the wound was sensed every three days. Case data sequence 201, case data sequence 202, case data sequence 203, and case data sequence 204 are based on multiple wound observation data recorded on the first, fourth, seventh, and Nth days, respectively. Establish. For example, {2.0, 3.0, 0.5, 50, 32, . 50. The wound temperature is 32... etc.; {3.0, 2.0, 0.4, 25, 31, ...} of the case data sequence 202 can represent that the wound length sensed on the 4th day is 3.0, the wound width is 2.0, and the wound depth is 0.4, the amount of exudate is 25, the temperature of the wound is 31, etc.; {2.5, 1.5, 0.3, 30, 31, ...} of the case data sequence 203 can represent that the wound length sensed on the 7th day is 2.5, and the wound width is 1.5. The depth of the wound is 0.3, the amount of exudate is 30, the temperature of the wound is 31, etc.; all data in the case data sequence 201 is 0, which means that the wound is detected to be completely healed on the Nth day.

回到第1圖,方法100繼續進行操作102。於操作102,接收傷口之當前傷口表徵,其中當前傷口表徵包含多項傷口觀察數據。然後,方法100進入操作103。Returning to FIG. 1 , the method 100 continues with operation 102 . At operation 102, a current wound representation of the wound is received, wherein the current wound representation includes a plurality of wound observation data. The method 100 then proceeds to operation 103 .

根據本發明之實施例,上述當前傷口表徵所包含的多項傷口觀察數據可對應前述參考案例之表徵記錄所包含的多項傷口觀察數據。也就是說,當前傷口表徵可包含例如傷口位置(例如背部、腳踝、手腕…等)、傷口長度、傷口寬度、傷口深度、傷口範圍表面積、滲出液量、滲出液性質、滲出液顏色、傷口溫度、傷口組織...等多項傷口觀察數據。同樣地,在某些實施例中,可運用傷口機來取得病患傷口於當前的傷口表徵中的多項傷口觀察數據。舉例來說,可運用傷口機中的色彩感測器取得傷口組織數據、可運用傷口機中的深度感測器取得傷口範圍表面積數據,以及可運用傷口機中的溫度感測器取得傷口溫度數據。According to an embodiment of the present invention, the multiple items of wound observation data included in the above-mentioned current wound characterization may correspond to the multiple items of wound observation data included in the characterization record of the aforementioned reference case. That is, the current wound characterization may include, for example, wound location (eg, back, ankle, wrist, etc.), wound length, wound width, wound depth, wound extent surface area, exudate volume, exudate properties, exudate color, wound temperature , wound tissue... and other wound observation data. Likewise, in some embodiments, a wound machine may be used to obtain multiple wound observations of the patient's wound in the current wound characterization. For example, the color sensor in the wound machine can be used to obtain wound tissue data, the depth sensor in the wound machine can be used to obtain wound area surface area data, and the temperature sensor in the wound machine can be used to obtain wound temperature data .

回到第1圖,方法100繼續進行操作103。於操作103,基於傷口之多項傷口觀察數據,建立當前資料序列。然後,方法100進入操作104。Returning to FIG. 1 , the method 100 continues with operation 103 . In operation 103, a current data sequence is established based on the multiple wound observation data of the wound. The method 100 then proceeds to operation 104 .

根據本發明之實施例,上述當前資料序列之記載形式亦如同前述參考案例之案例資料序列。也就是說,當前資料序列可被記載為{x 1, x 2, x 3, x 4, x 5, …}的形式,如同第2圖中的案例資料序列201、案例資料序列202或案例資料序列203。 According to the embodiment of the present invention, the recording format of the above-mentioned current data sequence is also the same as that of the case data sequence of the aforementioned reference case. That is to say, the current data sequence can be recorded in the form of {x 1 , x 2 , x 3 , x 4 , x 5 , ...}, like the case data sequence 201 , the case data sequence 202 or the case data in Figure 2 sequence 203.

在某些實施例中,於操作103,傷口之多項傷口觀察數據會先經過一標準化(standardization)處理程序,之後再以標準化後的傷口觀察數據建立當前資料序列。由於標準化為習知的數據處理技術,故此處不贅述之。在某些實施例中,各項傷口觀察數據之範圍,可經由某些數學函式之運算,而轉換至一特定值域之範圍(例如0~5)。In some embodiments, in operation 103, a plurality of wound observation data of the wound are first subjected to a standardization process, and then a current data sequence is created based on the standardized wound observation data. Since normalization is a well-known data processing technique, it will not be repeated here. In some embodiments, the range of each wound observation data can be converted to a range of a specific value range (eg, 0-5) through the operation of certain mathematical functions.

回到第1圖,方法100繼續進行操作104。於操作104,計算當前資料序列與每個參考案例的每個案例資料序列之相似度。舉例來說,計算當前資料序列與第2圖中的參考案例200之第1天的案例資料序列201、第4天的案例資料序列202、第7天之案例資料序列203…(依此類推)之相似度,並且計算當前資料序列與其他每個參考案例的每個案例資料序列之相似度。然後,方法100進入操作105。Returning to FIG. 1 , the method 100 continues with operation 104 . In operation 104, the similarity between the current data sequence and each case data sequence of each reference case is calculated. For example, calculate the current data series and the reference case 200 in Figure 2, the case data series 201 on the 1st day, the case data series 202 on the 4th day, the case data series 203 on the 7th day... (and so on) and calculate the similarity between the current data sequence and each case data sequence of each other reference case. The method 100 then proceeds to operation 105 .

在某些實施例中,上述相似度之計算係將當前資料序列與每個案例資料序列視為一座標系(coordinate system)上的兩點,再去計算該兩點之間的歐氏距離(Euclidean Distance)。具體而言,將當前資料序列與一案例資料序列中的每個數值相減以取得多個差值,再求這些差值之平方和(sum of squares),最後再開根號以取得該當前資料序列與該案例資料序列之歐氏距離。舉例來說,假設當前資料序列為{x 1, x 2, x 3, …, x n},一範例的案例資料序列為{y 1, y 2, y 3, …, y n},則該當前資料序列與該範例的案例資料序列之歐氏距離為

Figure 02_image001
。應注意的係,計算得出的歐氏距離越小,代表相似度越高。 In some embodiments, the above calculation of similarity is to regard the current data sequence and each case data sequence as two points on a coordinate system, and then calculate the Euclidean distance between the two points ( Euclidean Distance). Specifically, the current data series is subtracted from each value in a case data series to obtain multiple differences, then the sum of squares of these differences is calculated, and finally the square is opened to obtain the current data. The Euclidean distance between the sequence and the sequence of the case data. For example, if the current data sequence is {x 1 , x 2 , x 3 , …, x n }, and an example case data sequence is {y 1 , y 2 , y 3 , …, y n }, then the The Euclidean distance between the current data sequence and the case data sequence of this example is
Figure 02_image001
. It should be noted that the smaller the calculated Euclidean distance, the higher the similarity.

回到第1圖,方法100繼續進行操作105。於操作105,從每個參考案例的案例資料序列中,選取與當前資料序列之相似度最高(例如歐氏距離最小)的案例資料序列,作為每個參考案例中的相似案例資料序列。舉例來說,從第2圖中的參考案例200的所有案例資料序列中,選取與當前資料序列之相似度最高(例如歐氏距離最小)的案例資料序列,作為參考案例200中的相似案例資料序列,並且對其他參考案例也進行相同的操作,以取得多個相似案例資料序列。然後,方法100進入操作106。Returning to FIG. 1 , the method 100 continues with operation 105 . In operation 105, from the case data sequence of each reference case, the case data sequence with the highest similarity with the current data sequence (eg, the smallest Euclidean distance) is selected as the similar case data sequence in each reference case. For example, from all the case data sequences of the reference case 200 in Figure 2, select the case data sequence with the highest similarity to the current data sequence (for example, the smallest Euclidean distance), as the similar case data in the reference case 200. sequence, and perform the same operation on other reference cases to obtain multiple similar case data sequences. The method 100 then proceeds to operation 106 .

根據本發明之實施例,上述每個相似案例資料序列各自對應於一相似案例處置方針。相似案例處置方針係基於用以建立相似案例資料序列的表徵記錄所對應的質性問卷紀錄及處置記錄所建立。舉例來說,假設第2圖中的參考案例200中的相似案例資料序列為案例資料序列203,這意味著在參考案例200的多次評估結果中,屬第7天的傷口表徵與病患當前的傷口表徵最為類似,因此相似案例處置方針係依據第7天的質性問卷紀錄及處置記錄所建立。According to an embodiment of the present invention, each of the above-mentioned similar case data sequences corresponds to a similar case handling policy. Similar case treatment policies are established based on qualitative questionnaire records and treatment records corresponding to the representation records used to establish similar case data sequences. For example, it is assumed that the similar case data sequence in the reference case 200 in Figure 2 is the case data sequence 203, which means that in the multiple evaluation results of the reference case 200, the wound representation on the 7th day is the same as the patient's current condition. The wounds of the patients were most similar, so the treatment strategy for similar cases was established based on the qualitative questionnaire records and treatment records on the 7th day.

回到第1圖,方法100繼續進行操作106。於操作106,使用該等相似案例資料序列及其對應的相似案例處置方針執行多元回歸分析(multiple regression analysis),以計算出適應度函數(fitness function),其中適應度函數之應變數為傷口變化。然後,方法100進入操作107。Returning to FIG. 1 , the method 100 continues with operation 106 . In operation 106, multiple regression analysis is performed using the similar case data sequences and their corresponding similar case treatment policies to calculate a fitness function, wherein the strain factor of the fitness function is the wound change . The method 100 then proceeds to operation 107 .

第3A圖係根據本發明之實施例所提供多元回歸分析所需輸入資料300A的範例。如第3圖所示,輸入資料300A包含來自多個參考案例之相似案例資料序列301、相似案例處置方針302及傷口變化303。傷口變化303係藉由比較各個參考案例中的相似案例資料序列與其前一筆案例資料序列之間的差異所取得。舉例來說,假設第2圖中的參考案例200中的相似案例資料序列為案例資料序列203,且第3A圖中的行304係參考案例200中的相似案例資料序列(即案例資料序列203)、相似案例處置方針(即依據第7天的質性問卷紀錄及處置記錄所建立的案例處置方針)及傷口變化之組合,則行304之傷口變化值即係藉由比較案例資料序列203與其前一筆案例資料序列(即案例資料序列202)之間的差異所取得。在各種不同的實施例中,傷口變化可以例如係傷口長度變化、傷口寬度變化、傷口表面積變化或傷口體積變化等。在第3A圖所示的範例中,傷口變化所指的是傷口體積變化。舉例來說,行304的傷口變化之值為案例資料序列203所指示的傷口體積(即傷口長度、傷口寬度與傷口深度之乘積)與案例資料序列202所指示的傷口體積之間的差異,如以下計算: 3.0*2.0*0.4 - 2.5*1.5*0.3 = 2.275 FIG. 3A is an example of input data 300A required for multiple regression analysis according to an embodiment of the present invention. As shown in FIG. 3, input data 300A includes similar case data sequences 301, similar case treatment policies 302, and wound changes 303 from multiple reference cases. Wound changes 303 are obtained by comparing the differences between the similar case data sequence in each reference case and its previous case data sequence. For example, it is assumed that the similar case data sequence in the reference case 200 in Figure 2 is the case data sequence 203, and the row 304 in Figure 3A is the similar case data sequence in the reference case 200 (ie the case data sequence 203) , similar case treatment policy (that is, the case treatment policy established based on the qualitative questionnaire records and treatment records on the 7th day) and the combination of wound changes, the wound change value of row 304 is calculated by comparing the case data series 203 with the previous one. Differences between case data sequences (ie case data sequence 202) are obtained. In various embodiments, the wound change may be, for example, a change in wound length, a change in wound width, a change in wound surface area, or a change in wound volume, and the like. In the example shown in Figure 3A, wound change refers to wound volume change. For example, the value of the wound change in row 304 is the difference between the wound volume indicated by case data sequence 203 (ie, the product of wound length, wound width, and wound depth) and the wound volume indicated by case data sequence 202, such as The following calculation: 3.0*2.0*0.4 - 2.5*1.5*0.3 = 2.275

回到第1圖,方法100繼續進行操作107。於操作107,使用當前資料序列與適應度函數執行參數最佳化演算法,以計算出使傷口變化最大化的最佳處置方針及對應最佳處置方針的預期傷口變化值。最佳處置方針及預期傷口變化值可被展示於顯示裝置,以提供傷口照護處置上的建議給照護者。Returning to FIG. 1 , the method 100 continues with operation 107 . At operation 107, a parameter optimization algorithm is performed using the current data sequence and the fitness function to calculate an optimal treatment policy that maximizes the wound change and an expected wound change value corresponding to the optimal treatment policy. Optimal treatment guidelines and expected wound change values can be displayed on the display device to provide caregivers with advice on wound care management.

根據本發明之實施例,參數最佳化演算法以當前資料序列及適應度函數作為輸入,其作用在於找到最佳的一案例處置方針,也就是最佳的質性問卷紀錄之數據及處置記錄之數據的組合(例如第3A圖中翻身頻率、敷料、傷口護理技術…等的組合),能使得傷口變化(例如傷口長度變化、傷口寬度變化、傷口表面積變化或傷口體積變化)最大化。此時的案例處置方針即為最佳案例處置方針,被最大化的傷口變化之值即為預期傷口變化值。舉例來說,假設有一第一處置方針”翻身頻率3次、敷料為泡棉、傷口護理技術為優…”所對應的傷口變化之值為3.5,而透過參數最佳化演算法判定無法藉由改變第一處置方針來使傷口變化之值大於3.5,則第一處置方針即為最佳處置方針,而對應第一處置方針的預期傷口變化值即為3.5。在某些實施例中,參數最佳化演算法可以係例如基因演算法(Genetic Algorithm;GA)、蟻群演算法(Ant Colony Optimization)、粒子群最佳化演算法(Particle Swarm Optimization;PSO)等各種啟發式演算法(heuristic algorithm),本發明並不以此為限。According to the embodiment of the present invention, the parameter optimization algorithm takes the current data sequence and the fitness function as input, and its function is to find the best case treatment policy, that is, the best qualitative questionnaire record data and treatment records The combination of data (eg, the combination of turning frequency, dressing, wound care technique, etc. in Figure 3A) maximizes wound changes (eg, changes in wound length, changes in wound width, changes in wound surface area, or changes in wound volume). The case treatment policy at this time is the best case treatment policy, and the value of the maximized wound change is the expected wound change value. For example, suppose there is a first treatment policy of "turning frequency 3 times, dressing with foam, excellent wound care technology..." and the corresponding wound change value is 3.5. If the first treatment policy is changed so that the wound change value is greater than 3.5, the first treatment policy is the optimal treatment policy, and the expected wound change value corresponding to the first treatment policy is 3.5. In some embodiments, the parameter optimization algorithm may be, for example, Genetic Algorithm (GA), Ant Colony Optimization (Ant Colony Optimization), Particle Swarm Optimization (PSO) and other heuristic algorithms, the present invention is not limited to this.

第3B圖係根據本發明之較佳實施例所提供多元回歸分析所需輸入資料300B的範例。第3B圖與第3A圖之間的差異在於傷口變化303更包含傷口長度變化、傷口寬度變化及傷口深度變化等三個維度,意味著執行多元回歸分析所計算出的適應度函數具有傷口長度變化、傷口寬度變化及傷口深度變化等三個應變數。在本揭露提供的範例中,行304之傷口長度變化之值(0.5)為案例資料序列203所指示的傷口長度(2.5)與案例資料序列202所指示的傷口長度(3.0)之間的差異,如以下計算: 3.0 - 2.5 = 0.5 行304之傷口寬度變化之值(0.5)為案例資料序列203所指示的傷口寬度(1.5)與案例資料序列202所指示的傷口寬度(2.0)之間的差異,如以下計算: 2.0 - 1.5 = 0.5 行304之傷口深度變化之值(0.1)為案例資料序列203所指示的傷口深度(0.3)與案例資料序列202所指示的傷口深度(0.4)之間的差異,如以下計算: 0.4 - 0.3 = 0.1 FIG. 3B is an example of input data 300B required for multiple regression analysis according to a preferred embodiment of the present invention. The difference between Fig. 3B and Fig. 3A is that the wound change 303 further includes three dimensions: wound length change, wound width change, and wound depth change, which means that the fitness function calculated by performing multiple regression analysis has wound length change , wound width change and wound depth change. In the example provided in this disclosure, the value of the wound length change (0.5) in row 304 is the difference between the wound length (2.5) indicated by the case data sequence 203 and the wound length (3.0) indicated by the case data sequence 202, Calculate as follows: 3.0 - 2.5 = 0.5 The value of the change in wound width (0.5) for row 304 is the difference between the wound width (1.5) indicated by case data series 203 and the wound width (2.0) indicated by case data series 202, calculated as follows: 2.0 - 1.5 = 0.5 The value of the change in wound depth (0.1) for row 304 is the difference between the wound depth (0.3) indicated by case data series 203 and the wound depth (0.4) indicated by case data series 202, calculated as follows: 0.4 - 0.3 = 0.1

在第3B圖所示較佳實施例中,由於適應度函數具有傷口長度變化、傷口寬度變化及傷口深度變化等三個應變數,故參數最佳化演算法所輸出的預期傷口變化值為預期傷口長度變化值、預期傷口寬度變化值與預期傷口深度變化值之組合,而參數最佳化演算法所最大化的對象為傷口體積變化。舉例來說,假設當前資料序列所指示當前傷口長度為10,傷口寬度為5,傷口深度為0.5,有一第二處置方針”翻身頻率3次、敷料為泡棉、傷口護理技術為優…”所對應的傷口長度變化之值為2,傷口寬度變化之值為1,傷口深度變化之值為0.1,則第二處置方針所對應的傷口體積變化即為:當前傷口長度、當前傷口寬度與當前傷口深度三者的乘積,減去「當前傷口長度減去傷口長度變化之值」、「當前傷口寬度減去傷口寬度變化之值」與「當前傷口深度減去傷口深度變化之值」三者的乘積,如以下計算: 10*5*0.5 - (10-2)*(5-1)*(0.5-0.1) = 12.2 而透過參數最佳化演算法判定無法藉由改變第二處置方針來使傷口體積變化之值大於12.2,則第二處置方針即為最佳處置方針,而對應第二處置方針的預期傷口長度變化值即為2,預期傷口寬度變化值即為1,預期傷口寬度即為0.1。 In the preferred embodiment shown in Fig. 3B, since the fitness function has three strain numbers, such as wound length change, wound width change and wound depth change, the expected wound change value output by the parameter optimization algorithm is expected The combination of the wound length change value, the expected wound width change value and the expected wound depth change value, and the object maximized by the parameter optimization algorithm is the wound volume change. For example, assuming that the current wound length indicated by the current data sequence is 10, the wound width is 5, and the wound depth is 0.5, and there is a second treatment policy "turning frequency 3 times, the dressing is foam, and the wound care technique is excellent..." The corresponding change in wound length is 2, the change in wound width is 1, and the change in wound depth is 0.1, then the change in wound volume corresponding to the second treatment policy is: current wound length, current wound width and current wound The product of the three depths, minus the product of "the current wound length minus the change in the wound length", "the current wound width minus the change in the wound width", and "the current wound depth minus the change in the wound depth". , calculated as follows: 10*5*0.5 - (10-2)*(5-1)*(0.5-0.1) = 12.2 The parameter optimization algorithm determines that the change in wound volume cannot be changed by changing the second treatment policy to a value greater than 12.2, then the second treatment policy is the optimal treatment policy, and the expected change in wound length corresponding to the second treatment policy The value is 2, the expected wound width change value is 1, and the expected wound width is 0.1.

在某些實施例中,執行完方法100中的操作107之後,更繼續執行方法400。第4圖係根據本發明之實施例所繪示的方法400之流程圖,第5圖則係根據本發明之較佳實施例所提供執行方法400的過程中所產生的一系列最佳處置方針、一系列預期傷口變化值及一系列預期資料序列之範例。以下的敘述將需要互相搭配地參閱第4圖及第5圖,以更佳地理解本揭露。應注意的係,第5圖中各個表格內的數值,僅作為範例以便於敘述本發明之實施例,而並非意圖限制本發明。In some embodiments, after the operation 107 in the method 100 is performed, the method 400 is further performed. FIG. 4 is a flowchart of a method 400 according to an embodiment of the present invention, and FIG. 5 is a series of optimal treatment policies generated during the process of executing the method 400 provided by a preferred embodiment of the present invention , an example of a series of expected wound change values and a series of expected data series. The following description will need to refer to FIG. 4 and FIG. 5 in conjunction with each other for a better understanding of the present disclosure. It should be noted that the numerical values in each table in FIG. 5 are only used as examples to facilitate the description of the embodiments of the present invention, and are not intended to limit the present invention.

如第4圖所示,方法400包含操作401-404,且方法400起始於執行完操作107,然後進入操作401。於操作401,使用當前資料序列及預期傷口變化值估算預期資料序列,其中預期資料序列包含至少一尺寸參數。然後,方法400進入操作402。As shown in FIG. 4 , method 400 includes operations 401 - 404 , and method 400 begins by performing operation 107 and then proceeds to operation 401 . In operation 401, an expected data series is estimated using the current data series and the expected wound change value, wherein the expected data series includes at least one size parameter. Method 400 then proceeds to operation 402 .

根據本發明之實施例,上述的預期資料序列為當前資料序列與預期傷口變化值相減之結果。在某些實施例中,上述預期資料序列所包含的至少一尺寸參數,可以係預期傷口長度、預期傷口寬度、預期傷口深度或者上述的任何一種組合。According to an embodiment of the present invention, the above-mentioned expected data sequence is the result of subtracting the current data sequence and the expected wound change value. In some embodiments, the at least one size parameter included in the expected data sequence may be expected wound length, expected wound width, expected wound depth, or any combination of the above.

在較佳實施例中,適應度函數具有傷口長度變化、傷口寬度變化及傷口深度變化等三個應變數,故參數最佳化演算法所輸出的預期傷口變化值包含預期傷口長度變化值、預期傷口寬度變化值及預期傷口深度變化值,而預期資料序列所包含的尺寸參數為預期傷口長度、預期傷口寬度及預期傷口深度。以第5圖為例,根據當下時間點的傷口病況所建立的當前資料序列501,指示當下的傷口長度為10,傷口寬度為5,傷口深度為0.5。經執行完操作107後,得到最佳處置方針502及預期傷口變化值503,其中預期傷口變化值503包含預期傷口長度變化值(0.6)、預期傷口寬度變化值(0.3)及預期傷口深度變化值(0.1)。然後,經由操作401,將當前資料序列501所指示的傷口長度(10)、傷口寬度(5)及傷口深度(0.5),與預期傷口變化值503中的預期傷口長度變化值(0.6)、預期傷口寬度變化值(0.3)及預期傷口深度變化值(0.1)相減,得到預期資料序列504,如以下計算: 預期資料序列504之預期傷口長度:10 - 0.6 = 9.4 預期資料序列504之預期傷口寬度:5 - 0.3 = 4.7 預期資料序列504之預期傷口深度:0.5 - 0.1 = 0.4 In a preferred embodiment, the fitness function has three strain numbers such as wound length change, wound width change and wound depth change, so the expected wound change value output by the parameter optimization algorithm includes the expected wound length change value, the expected wound length change value, Wound width change value and expected wound depth change value, and the size parameters included in the expected data series are expected wound length, expected wound width and expected wound depth. Taking Fig. 5 as an example, the current data sequence 501 established according to the wound condition at the current time point indicates that the current wound length is 10, the wound width is 5, and the wound depth is 0.5. After the operation 107 is performed, the optimal treatment policy 502 and the expected wound change value 503 are obtained, wherein the expected wound change value 503 includes the expected wound length change value (0.6), the expected wound width change value (0.3) and the expected wound depth change value (0.1). Then, through operation 401, the wound length (10), wound width (5) and wound depth (0.5) indicated by the current data sequence 501 are compared with the expected wound length change value (0.6), the expected wound length change value (0.6) in the expected wound change value 503, The wound width change value (0.3) and the expected wound depth change value (0.1) are subtracted to obtain the expected data sequence 504, which is calculated as follows: Expected wound length for expected data sequence 504: 10 - 0.6 = 9.4 Expected Wound Width for Expected Data Sequence 504: 5 - 0.3 = 4.7 Expected wound depth for expected data series 504: 0.5 - 0.1 = 0.4

回到第4圖,方法400繼續進行操作402。於操作402,使用預期資料序列及適應度函數執行參數最佳化演算法,以計算出使傷口變化最大的下一最佳處置方針及對應下一最佳處置方針的下一預期傷口變化值。然後,方法400進入操作403。Returning to FIG. 4 , method 400 continues with operation 402 . In operation 402, a parameter optimization algorithm is performed using the expected data sequence and the fitness function to calculate the next best treatment policy that maximizes the wound change and the next expected wound change value corresponding to the next best treatment policy. The method 400 then proceeds to operation 403 .

根據本發明之實施例,操作402與操作107所採用的參數最佳化演算法及適應度函數類似,惟操作107係基於當前資料序列來搜尋最佳處置方針,而操作402係基於預期資料序列來搜尋下一最佳處置方針。以第5圖為例,在此較佳實施例中,預期資料序列504經執行完操作402後,得到下一最佳處置方針,即最佳處置方針505,以及下一預期傷口變化值,即預期傷口變化值506,其中預期傷口變化值506包含預期傷口長度變化值(0.8)、預期傷口寬度變化值(0.5)及預期傷口深度變化值(0.1)。According to an embodiment of the present invention, operation 402 is similar to the parameter optimization algorithm and fitness function used in operation 107, except that operation 107 searches for the best treatment policy based on the current data sequence, and operation 402 is based on the expected data sequence to search for the next best solution. Taking Fig. 5 as an example, in this preferred embodiment, after the expected data sequence 504 has completed the operation 402, the next best treatment policy, namely the best treatment policy 505, and the next expected wound change value, namely Expected wound change value 506, wherein expected wound change value 506 includes expected wound length change value (0.8), expected wound width change value (0.5), and expected wound depth change value (0.1).

回到第4圖,方法400繼續進行操作403。於操作403,使用預期資料序列及下一預期傷口變化值,估算下一預期資料序列。然後,方法400進入操作404。Returning to FIG. 4 , method 400 continues with operation 403 . At operation 403, the next expected data series is estimated using the expected data series and the next expected wound change value. Method 400 then proceeds to operation 404 .

根據本發明之實施例,操作403與操作401估算預期資料序列的作法類似,惟操作401係將當前資料序列與預期傷口變化值進行相減,而操作403係將預期資料序列與下一預期傷口變化值進行相減。以第5圖為例,在此較佳實施例中,操作403係將預期資料序列504與執行完操作402後所得到的下一預期傷口變化值,即預期傷口變化值506,進行相減,得到下一預期資料序列,即預期資料序列507,如以下計算: 預期資料序列507之預期傷口長度:9.4 - 0.8 = 8.6 預期資料序列507之預期傷口寬度:4.7 - 0.5 = 4.2 預期資料序列507之預期傷口深度:0.4 - 0.1 = 0.3 According to an embodiment of the present invention, operation 403 is similar to operation 401 for estimating the expected data series, except that operation 401 subtracts the current data series from the expected wound change value, and operation 403 compares the expected data series to the next expected wound The change value is subtracted. Taking FIG. 5 as an example, in this preferred embodiment, the operation 403 is to subtract the expected data sequence 504 and the next expected wound change value obtained after the operation 402 is performed, that is, the expected wound change value 506, to perform a subtraction, The next expected data sequence, that is, the expected data sequence 507, is obtained, as calculated as follows: Expected wound length for expected data series 507: 9.4 - 0.8 = 8.6 Expected Wound Width for Expected Data Sequence 507: 4.7 - 0.5 = 4.2 Expected wound depth for expected data series 507: 0.4 - 0.1 = 0.3

回到第4圖,方法400繼續進行操作404。於操作404,判斷於上一操作所得到的下一預期資料序列中的該至少一尺寸參數,是否皆為0。如果否,則方法400回到操作402。如果是,則代表已預期到傷口癒合,故結束方法400。Returning to FIG. 4 , method 400 continues with operation 404 . In operation 404, it is determined whether the at least one size parameter in the next expected data sequence obtained in the previous operation is all zero. If not, method 400 returns to operation 402 . If so, it means that wound healing is expected and method 400 ends.

以第5圖為例,在此較佳實施例中,預期資料序列507又會再經由執行操作402、操作403及操作404,以得出再下一個預期資料序列。如此不斷重複地執行操作402、操作403及操作404,直到預期到傷口癒合為止,如第5圖中的預期資料序列500之預期傷口長度、預期傷口寬度及預期傷口深度皆為0。Taking FIG. 5 as an example, in this preferred embodiment, the expected data sequence 507 will again perform operations 402 , 403 and 404 to obtain the next expected data sequence. Operation 402, operation 403 and operation 404 are repeatedly performed in this way until wound healing is expected. As shown in the expected data sequence 500 in FIG. 5, the expected wound length, expected wound width and expected wound depth are all zero.

根據本發明之實施例,於執行方法400之期間所產生的一系列最佳處置方針(例如第5圖中的最佳處置方針502、最佳處置方針505…)、一系列預期傷口變化值(例如第5圖中的預期傷口變化值503、預期傷口變化值506…)及一系列預期資料序列(例如第5圖中的預期資料序列504、預期資料序列507…),皆可被展示於顯示裝置,以提供傷口照護處置上的建議。在某些實施例中,可累計操作402及操作403於執行方法400之期間一共被執行了幾次,之後將操作402及操作403被執行的次數加1,再乘以傷口被感測的週期,即可得出預期的傷口癒合所需天數。舉例來說,若傷口被感測的週期為三天一次,且預期操作402及操作403需被執行8次後傷口才會癒合,則可預期該傷口癒合所需天數為27天,如以下計算: (8+1)*3 = 27 According to an embodiment of the present invention, a series of optimal treatment policies (eg optimal treatment policy 502, optimal treatment policy 505, ... in FIG. 5), a series of expected wound change values ( For example, expected wound change value 503, expected wound change value 506...) in Figure 5, and a series of expected data series (eg, expected data series 504, expected data series 507...) in Figure 5, can be displayed on the display device to provide advice on wound care management. In some embodiments, the total number of times operations 402 and 403 are performed during the execution of the method 400 may be accumulated, and then the number of times operations 402 and 403 are performed is incremented by 1, and then multiplied by the period during which the wound is sensed , the expected number of days it takes for the wound to heal. For example, if the wound is sensed once every three days, and it is expected that operation 402 and operation 403 will be performed 8 times before the wound will heal, it can be expected that the number of days required for the wound to heal is 27 days, as calculated as follows: : (8+1)*3 = 27

第6A圖係根據本發明之實施例所繪示的系統600A所處運算環境的方塊圖。如第6A圖所示,系統600A包含處理器601,處理器601可以有線或無線的方式連接儲存裝置602,以讀取被儲存於儲存裝置602中的參考案例,以執行如前所述的方法100及方法400。處理器601亦可以有線或無線的方式連接顯示裝置603,以將執行方法100及方法400所產生的一系列最佳處置方針、一系列預期傷口變化值及一系列預期資料序列,展示於顯示裝置603,以提供傷口照護處置上的建議給照護者。應注意的係,雖然第6A圖中的儲存裝置602並未被包含在系統600A之內,但在某些實施例中,系統600A可更包含儲存裝置602。同理,雖然第6A圖中的顯示裝置603並未被包含在系統600A之內,但在某些實施例中,系統600A可更包含顯示裝置603。FIG. 6A is a block diagram of a computing environment in which the system 600A is located according to an embodiment of the present invention. As shown in FIG. 6A, the system 600A includes a processor 601. The processor 601 can be connected to the storage device 602 in a wired or wireless manner to read reference cases stored in the storage device 602 to execute the aforementioned method. 100 and method 400. The processor 601 can also be connected to the display device 603 in a wired or wireless manner, so as to display a series of optimal treatment guidelines, a series of expected wound change values and a series of expected data series generated by executing the method 100 and the method 400 on the display device 603 to provide caregivers with advice on wound care management. It should be noted that although the storage device 602 in FIG. 6A is not included in the system 600A, in some embodiments, the system 600A may further include the storage device 602 . Similarly, although the display device 603 in FIG. 6A is not included in the system 600A, in some embodiments, the system 600A may further include the display device 603 .

處理器601可以係任何一種用於執行指令的裝置,例如中央處理器(CPU)、微處理器(microprocessor)、控制器、微控制器(microcontroller)或狀態機(state machine),本發明並不以此為限;儲存裝置602可以係任何一種用於儲存資料的裝置,例如磁碟驅動器、光儲存元件以及固態儲存裝置如隨機存取記憶體(RAM)、唯讀記憶體(ROM)、可拆卸媒體裝置、記憶卡或快閃記憶卡,本發明並不以此為限;顯示裝置603可以係任何一種用於顯示文字及圖像的裝置,例如LCD顯示器、LED顯示器、OLED顯示器或電漿顯示器,本發明並不以此為限。The processor 601 can be any device for executing instructions, such as a central processing unit (CPU), a microprocessor (microprocessor), a controller, a microcontroller (microcontroller) or a state machine (state machine), and the present invention does not Limited to this; the storage device 602 can be any device for storing data, such as disk drives, optical storage devices, and solid-state storage devices such as random access memory (RAM), read only memory (ROM), The present invention is not limited to removing the media device, memory card or flash memory card; the display device 603 can be any device for displaying text and images, such as LCD display, LED display, OLED display or plasma Display, the present invention is not limited to this.

第6B圖係根據本發明之另一實施例所繪示的系統600B所處運算環境的方塊圖。相較於第6A圖中的系統600A,系統600B更包含傷口機604,而傷口機604又包含色彩感測器605、深度感測器606及溫度感測器607,分別用以取得傷口組織數據、傷口範圍表面積數據及傷口溫度數據。傷口機604可以有線或無線的方式連接處理器601,以將取得的多項傷口觀察數據傳送給處理器601,於是處理器601可基於這些傷口觀察數據建立當前資料序列。應注意的係,雖然第6B圖中的儲存裝置602並未被包含在系統600B之內,但在某些實施例中,系統600B可更包含儲存裝置602。同理,雖然第6B圖中的顯示裝置603並未被包含在系統600B之內,但在某些實施例中,系統600B可更包含顯示裝置603。此外,雖然系統600B包含處理器601及處理器604,但本發明並無限制處理器601及處理器604是否被設置於同一電子裝置中。FIG. 6B is a block diagram of a computing environment in which the system 600B is located according to another embodiment of the present invention. Compared with the system 600A in FIG. 6A , the system 600B further includes a wound machine 604 , and the wound machine 604 further includes a color sensor 605 , a depth sensor 606 and a temperature sensor 607 for obtaining wound tissue data respectively. , wound area surface area data and wound temperature data. The wound machine 604 can be connected to the processor 601 in a wired or wireless manner, so as to transmit a plurality of obtained wound observation data to the processor 601, and then the processor 601 can establish a current data sequence based on the wound observation data. It should be noted that although the storage device 602 in FIG. 6B is not included in the system 600B, in some embodiments, the system 600B may further include the storage device 602 . Similarly, although the display device 603 in FIG. 6B is not included in the system 600B, in some embodiments, the system 600B may further include the display device 603 . In addition, although the system 600B includes the processor 601 and the processor 604, the present invention does not limit whether the processor 601 and the processor 604 are disposed in the same electronic device.

綜上,本發明所提供的傷口多重感測方法及傷口多重感測系統,能藉由參考過往累積的相似案例,基於當前傷口的病況推估傷口癒合的進度,並提供照護處置上的建議。In conclusion, the wound multi-sensing method and wound multi-sensing system provided by the present invention can estimate the progress of wound healing based on the current condition of the wound by referring to similar cases accumulated in the past, and provide suggestions on care and treatment.

在本說明書中以及申請專利範圍中的序號,例如「第一」、「第二」等等,僅係為了方便說明,彼此之間並沒有順序上的先後關係。The serial numbers in this specification and the scope of the patent application, such as "first", "second", etc., are only for convenience of description, and there is no sequential relationship between them.

以上段落使用多種層面描述。顯然的,本文的教示可以多種方式實現,而在範例中揭露之任何特定架構或功能僅為一代表性之狀況。根據本文之教示,任何熟知此技藝之人士應理解在本文揭露之各層面可獨立實作或兩種以上之層面可以合併實作。The above paragraphs use multiple levels of description. Obviously, the teachings herein can be implemented in a variety of ways, and any particular architecture or functionality disclosed in the examples is merely a representative case. Based on the teachings herein, anyone skilled in the art should understand that each aspect disclosed herein may be implemented independently or two or more aspects may be implemented in combination.

雖然本揭露已以實施例揭露如上,然其並非用以限定本揭露,任何熟習此技藝者,在不脫離本揭露之精神和範圍內,當可作些許之更動與潤飾,因此發明之保護範圍當視後附之申請專利範圍所界定者為準。Although the present disclosure has been disclosed above with examples, it is not intended to limit the present disclosure. Anyone who is familiar with the art can make some changes and modifications without departing from the spirit and scope of the present disclosure. Therefore, the protection scope of the invention is The scope of the patent application attached herewith shall prevail.

100:方法 101-107:操作 200:參考案例 201-204:案例資料序列 300A:輸入資料 301:相似案例資料序列 302:相似案例處置方針 303:傷口變化 304:行 300B:輸入資料 400:方法 401-404:操作 500,504,507:預期資料序列 501:當前資料序列 502,505:最佳處置方針 503,506:預期傷口變化值 600A:系統 601:處理器 602:儲存裝置 603:顯示裝置 600B:系統 604:傷口機 605:色彩感測器 606:深度感測器 607:溫度感測器 100: Method 101-107: Operations 200: Reference Case 201-204: Case data series 300A: Input data 301: Similar case data sequence 302: Similar Case Handling Policy 303: Wound changes 304: OK 300B: Input information 400: Method 401-404: Operations 500,504,507: Expected data series 501: Current data sequence 502, 505: Best Practices 503,506: Expected Wound Variation Values 600A: System 601: Processor 602: Storage Device 603: Display device 600B: System 604: Wound Machine 605: Color Sensor 606: Depth Sensor 607: Temperature sensor

本揭露將可從以下示範的實施例之敘述搭配附帶的圖式更佳地理解。此外,應被理解的係,在本揭露之流程圖中,各區塊的執行順序可被改變,且/或某些區塊可被改變、刪減或合併。第1圖係根據本發明之實施例所繪示的方法100之流程圖。 第2圖係根據本發明之實施例所提供的參考案例200之範例。 第3A圖係根據本發明之實施例所提供多元回歸分析所需輸入資料300A的範例。 第3B圖係根據本發明之較佳實施例所提供多元回歸分析所需輸入資料300B的範例。 第4圖係根據本發明之實施例所繪示的方法400之流程圖。 第5圖係根據本發明之較佳實施例所提供執行方法400的過程中所產生的一系列最佳處置方針、一系列預期傷口變化值及一系列預期資料序列之範例。 第6A圖係根據本發明之實施例所繪示的系統600A所處運算環境的方塊圖。 第6B圖係根據本發明之另一實施例所繪示的系統600B所處運算環境的方塊圖。 The present disclosure will be better understood from the following description of exemplary embodiments in conjunction with the accompanying drawings. In addition, it should be understood that, in the flowcharts of the present disclosure, the order of execution of various blocks may be changed, and/or certain blocks may be changed, omitted, or combined. FIG. 1 is a flowchart of a method 100 according to an embodiment of the present invention. FIG. 2 is an example of a reference case 200 provided according to an embodiment of the present invention. FIG. 3A is an example of input data 300A required for multiple regression analysis according to an embodiment of the present invention. FIG. 3B is an example of input data 300B required for multiple regression analysis according to a preferred embodiment of the present invention. FIG. 4 is a flowchart of a method 400 according to an embodiment of the present invention. FIG. 5 is an example of a series of optimal treatment guidelines, a series of expected wound change values, and a series of expected data series generated during the execution of method 400 according to a preferred embodiment of the present invention. FIG. 6A is a block diagram of a computing environment in which the system 600A is located according to an embodiment of the present invention. FIG. 6B is a block diagram of a computing environment in which the system 600B is located according to another embodiment of the present invention.

100:方法 101-107:操作 100: Method 101-107: Operations

Claims (14)

一種傷口多重感測方法,由一處理器所執行,包括:讀取複數個參考案例,其中每個該等參考案例包括對應於不同時間點的複數個案例資料序列;接收一傷口之一當前傷口表徵,其中該當前傷口表徵包括多項傷口觀察數據;基於該傷口之該多項傷口觀察數據,建立一當前資料序列;計算該當前資料序列與每個該等參考案例的每個該等案例資料序列之一相似度;從每個該等參考案例的該等案例資料序列中,選取與當前資料序列之該相似度最高的案例資料序列,作為每個該等參考案例中的一相似案例資料序列,其中該相似案例資料序列對應於一相似案例處置方針;使用該等相似案例資料序列及該等相似案例處置方針執行一多元回歸分析(multiple regression analysis),以計算出一適應度函數(fitness function),其中該適應度函數之應變數為一傷口變化;使用該當前資料序列與該適應度函數執行一參數最佳化演算法,以計算出使該傷口變化最大化的一最佳處置方針及對應該最佳處置方針的一預期傷口變化值。 A wound multiple sensing method, executed by a processor, comprising: reading a plurality of reference cases, wherein each of the reference cases includes a plurality of case data sequences corresponding to different time points; receiving a current wound of a wound Characterization, wherein the current wound representation includes a plurality of wound observation data; based on the plurality of wound observation data of the wound, a current data sequence is established; calculation of the current data sequence and each of the case data sequences of each of the reference cases a similarity degree; from the case data sequences of each of the reference cases, select the case data sequence with the highest similarity to the current data sequence as a similar case data sequence in each of the reference cases, wherein The similar case data sequence corresponds to a similar case treatment policy; a multiple regression analysis is performed using the similar case data sequence and the similar case treatment policy to calculate a fitness function , wherein the strain number of the fitness function is a wound change; a parameter optimization algorithm is performed using the current data sequence and the fitness function to calculate an optimal treatment policy that maximizes the wound change and the An expected wound change value that should be optimally managed. 如請求項1之傷口多重感測方法,更包括:第一操作:使用該當前資料序列及該預期傷口變化值估算一預期資料序列,其中該預期資料序列包括至少一尺寸參數; 第二操作:使用該預期資料序列及該適應度函數執行該參數最佳化演算法,以計算出使該傷口變化最大的下一最佳處置方針及對應該下一最佳處置方針的下一預期傷口變化值,再使用該預期資料序列及該下一預期傷口變化值,估算下一預期資料序列;其中,該下一預期資料序列被用作為新的該預期資料序列以重複執行該第二操作,直到計算出該下一預期資料序列中的該至少一尺寸參數皆為0。 The wound multiple sensing method of claim 1, further comprising: a first operation: using the current data sequence and the expected wound change value to estimate an expected data sequence, wherein the expected data sequence includes at least one size parameter; Second operation: use the expected data sequence and the fitness function to perform the parameter optimization algorithm to calculate the next best treatment policy that maximizes the wound change and the next best treatment policy corresponding to the next best treatment policy the expected wound change value, and then use the expected data sequence and the next expected wound change value to estimate the next expected data sequence; wherein, the next expected data sequence is used as the new expected data sequence to repeat the second execution The operation is performed until the at least one size parameter in the next expected data sequence is calculated to be 0. 如請求項2之傷口多重感測方法,其中該至少一尺寸參數為一預期傷口長度、一預期傷口寬度及一預期傷口深度。 The wound multiple sensing method of claim 2, wherein the at least one size parameter is an expected wound length, an expected wound width and an expected wound depth. 如請求項2之傷口多重感測方法,更包括:累計該第二操作被執行的次數,直到計算出該下一預期資料序列中的該至少一尺寸參數皆為0;將該第二操作被執行的次數加1,再乘以被感測的週期,以得出一預期傷口癒合天數。 The wound multiple sensing method of claim 2, further comprising: accumulating the number of times the second operation is performed until the at least one size parameter in the next expected data sequence is calculated to be 0; The number of executions is incremented by 1 and multiplied by the period sensed to obtain an expected wound healing days. 如請求項1之傷口多重感測方法,其中該傷口變化包括下列三個維度:一傷口長度變化、一傷口寬度變化及一傷口深度變化;及其中使該傷口變化最大化包括:使一傷口體積變化最大化;及其中該預期傷口變化值包括一預期傷口長度變化值、一預期傷口寬度變化值與一預期傷口深度變化值。 The wound multiple sensing method of claim 1, wherein the wound variation includes the following three dimensions: a wound length variation, a wound width variation, and a wound depth variation; and wherein maximizing the wound variation comprises: maximizing a wound volume and wherein the expected wound variation value includes an expected wound length variation value, an expected wound width variation value and an expected wound depth variation value. 如請求項1之傷口多重感測方法,更包括:使用一傷口機中的一色彩感測器以取得該多項傷口觀察數據中 的一傷口組織數據;使用該傷口機中的一深度感測器以取得該多項傷口觀察數據中的一傷口範圍表面積數據;使用該傷口機中的一溫度感測器以取得該多項傷口觀察數據中的一傷口溫度數據。 The wound multiple sensing method of claim 1, further comprising: using a color sensor in a wound machine to obtain the multiple wound observation data a wound tissue data; use a depth sensor in the wound machine to obtain a wound area surface area data in the plurality of wound observation data; use a temperature sensor in the wound machine to obtain the plurality of wound observation data A wound temperature data in . 如請求項1之傷口多重感測方法,其中每個該等參考案例,更包括一表徵記錄、一質性問卷記錄及一照護處置記錄;其中該等案例資料序列係基於該表徵記錄所建立;及其中該等相似案例處置方針係基於該質性問卷記錄及該照護處置記錄所建立。 According to the wound multi-sensing method of claim 1, each of the reference cases further includes a characterization record, a qualitative questionnaire record and a care treatment record; wherein the case data sequence is established based on the characterization record; and where such similar case disposition policies are established based on the qualitative questionnaire records and the care disposition records. 一種傷口多重感測系統,包括一處理器,用以執行:讀取複數個參考案例,其中每個該等參考案例包括對應於不同時間點的複數個案例資料序列;接收一傷口之一當前傷口表徵,其中該當前傷口表徵包括多項傷口觀察數據;基於該傷口之該多項傷口觀察數據,建立一當前資料序列;計算該當前資料序列與每個該等參考案例的每個該等案例資料序列之一相似度;從每個該等參考案例的該等案例資料序列中,選取與當前資料序列之該相似度最高的案例資料序列,作為每個該等參考案例中的一相似案例資料序列,其中該相似案例資料序列對應於一相似案例處置方針; 使用該等相似案例資料序列及該等相似案例處置方針執行一多元回歸分析,以計算出一適應度函數,其中該適應度函數之應變數為一傷口變化;使用該當前資料序列與該適應度函數執行一參數最佳化演算法,以計算出使該傷口變化最大化的一最佳處置方針及對應該最佳處置方針的一預期傷口變化值。 A wound multiple sensing system, comprising a processor for performing: reading a plurality of reference cases, wherein each of the reference cases includes a plurality of case data sequences corresponding to different time points; receiving a current wound of a wound Characterization, wherein the current wound representation includes a plurality of wound observation data; based on the plurality of wound observation data of the wound, a current data sequence is established; calculation of the current data sequence and each of the case data sequences of each of the reference cases a similarity degree; from the case data sequences of each of the reference cases, select the case data sequence with the highest similarity to the current data sequence as a similar case data sequence in each of the reference cases, wherein The similar case data sequence corresponds to a similar case handling policy; performing a multiple regression analysis using the similar case data series and the similar case treatment policies to calculate a fitness function, wherein the strain of the fitness function is a wound change; using the current data series and the adaptation The degree function performs a parameter optimization algorithm to calculate an optimal treatment policy that maximizes the wound change and an expected wound change value corresponding to the optimal treatment policy. 如請求項8之傷口多重感測系統,該處理器更執行:第一操作:使用該當前資料序列及該預期傷口變化值估算一預期資料序列,其中該預期資料序列包括至少一尺寸參數;第二操作:使用該預期資料序列及該適應度函數執行該參數最佳化演算法,以計算出使該傷口變化最大的下一最佳處置方針及對應該下一最佳處置方針的下一預期傷口變化值,再使用該預期資料序列及該下一預期傷口變化值,估算下一預期資料序列;其中,該下一預期資料序列被該處理器用作為新的該預期資料序列以重複執行該第二操作,直到計算出該下一預期資料序列中的該至少一尺寸參數皆為0。 According to the wound multi-sensing system of claim 8, the processor further performs: a first operation: using the current data sequence and the expected wound change value to estimate an expected data sequence, wherein the expected data sequence includes at least one size parameter; Second operation: use the expected data sequence and the fitness function to execute the parameter optimization algorithm to calculate the next best treatment policy that maximizes the wound change and the next best treatment policy corresponding to the next best treatment policy. wound change value, and then use the expected data sequence and the next expected wound change value to estimate the next expected data sequence; wherein, the next expected data sequence is used by the processor as the new expected data sequence to repeatedly execute the first The second operation is performed until the at least one size parameter in the next expected data sequence is calculated to be 0. 如請求項9之傷口多重感測系統,其中該至少一尺寸參數為一預期傷口長度、一預期傷口寬度及一預期傷口深度。 The wound multi-sensing system of claim 9, wherein the at least one dimension parameter is an expected wound length, an expected wound width and an expected wound depth. 如請求項9之傷口多重感測系統,該處理器更執行:累計該第二操作被執行的次數,直到計算出該下一預期資料序列中的該至少一尺寸參數皆為0; 將該第二操作被執行的次數加1,再乘以被感測的週期,以得出一預期傷口癒合天數。 According to the wound multiple sensing system of claim 9, the processor further executes: accumulating the number of times the second operation is performed until it is calculated that the at least one size parameter in the next expected data sequence is all 0; The number of times the second operation is performed is added by 1 and multiplied by the sensed period to obtain an expected number of days for wound healing. 如請求項8之傷口多重感測系統,其中該傷口變化包括下列三個維度:一傷口長度變化、一傷口寬度變化及一傷口深度變化;及其中使該傷口變化最大化包括:使一傷口體積變化最大化;及其中該預期傷口變化值包括一預期傷口長度變化值、一預期傷口寬度變化值與一預期傷口深度變化值。 The wound multiple sensing system of claim 8, wherein the wound variation includes the following three dimensions: a wound length variation, a wound width variation, and a wound depth variation; and wherein maximizing the wound variation comprises: maximizing a wound volume and wherein the expected wound variation value includes an expected wound length variation value, an expected wound width variation value and an expected wound depth variation value. 如請求項8之傷口多重感測系統,更包括一傷口機,該傷口機包括:一色彩感測器,用以取得該多項傷口觀察數據中的一傷口組織數據;一深度感測器,用以取得該多項傷口觀察數據中的一傷口範圍表面積數據;一溫度感測器,用以取得該多項傷口觀察數據中的一傷口溫度數據。 The wound multi-sensing system of claim 8 further includes a wound machine, the wound machine comprising: a color sensor for obtaining a wound tissue data among the plurality of wound observation data; a depth sensor for to obtain a wound area surface area data among the multiple wound observation data; a temperature sensor for obtaining a wound temperature data among the multiple wound observation data. 如請求項8之傷口多重感測系統,其中每個該等參考案例更包括一表徵記錄、一質性問卷記錄及一照護處置記錄;其中該等案例資料序列係基於該表徵記錄所建立;及其中該等相似案例處置方針係基於該質性問卷記錄及該照護處置記錄所建立。 The wound multi-sensing system of claim 8, wherein each of the reference cases further includes a characterization record, a qualitative questionnaire record, and a care treatment record; wherein the case data sequences are established based on the characterization record; and Wherein, the similar case disposal policies are established based on the qualitative questionnaire records and the care disposal records.
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CN105426167A (en) * 2015-10-08 2016-03-23 隗刚 Wound treatment APP (application) system based on big data processing
CN109069712A (en) * 2016-05-13 2018-12-21 史密夫及内修公开有限公司 Enable the wound monitoring and therapy devices of sensor

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