TWI770667B - Blood glucose control solution packaging and blood glucose test kits - Google Patents

Abstract

A blood glucose control solution packaging, comprising a container, a first glucose control solution and a cover film. The container defines a first accommodating space. The first blood glucose control solution is stored in the first accommodating space. The cover film covers the surface opening of the first accommodating space of the container, so as to seal the first glycemic control solution.

Description

Blood glucose quality control liquid packaging body and blood glucose test kit

The present invention relates to a blood sugar monitoring liquid package and a blood glucose test kit, in particular to a blood sugar monitoring liquid package with a soft surface capable of allowing an electrochemical test piece to be inserted; and a blood sugar test kit comprising the package.

The main function of the blood glucose quality control solution is to confirm that the blood glucose machine is functioning properly and to avoid incorrect results due to instrument failure, which will affect the user's health and self-assessment.

Since there are process differences between test pieces and the sensor also has differences in measurement accuracy, this will also cause measurement deviations. In addition, measurement deviations may also originate from improper operation by the user. Therefore, it is necessary to perform a quality control procedure of the sensing system 100 during predetermined intervals or after improper operation in order to detect and understand whether the measurement error of the sensing system 100 exceeds the quality specification. For these purposes, the manufacturer of the sensing system 100 proposes a quality control fluid for use with the sensing system 100 . Quality control fluids typically consist of a hydrophilic solution containing a buffer and a known and predetermined concentration of the analyte.

FIG. 1 shows a schematic diagram of the conventional operation when using QC fluid for calibration. As shown in Figure 1, the In the prior art, the quality control fluid 291 is contained in a bottle 290 with a lid. When the user calibrates the electrochemical sensor 200 with the QC fluid, the user needs to take out the bottle 290 containing the QC fluid 291 , open the bottle cap, and drop the QC fluid 291 on the electrochemical test strip 110 . Next, the electrochemical sensor 200 requires the user to perform an initial test protocol, such as inputting a specific code or pressing a special button or key on the electrochemical sensor 200 . This initial protocol informs the electrochemical sensor 200 that the measurement sample this time is a quality control fluid rather than an actual patient sample.

However, when there are many patients and a large number of operations are required, it is sometimes necessary to use the quality control fluid 291 repeatedly for testing, and it is often necessary to replace the quality control fluid 291 with a different quality control fluid 291 for testing and calibration, for example, a low blood sugar quality control fluid ( Glucose Control Low solution (GCL) and Glucose Control High solution (GCH) were replaced. At this time, the user needs to constantly replace the bottle, and sometimes forgets to carry one of the different quality control fluids, and takes time to take it out again, which is time-consuming and time-consuming.

Therefore, there is still room for further improvement in the blood glucose monitoring liquid packaging body according to the prior art, and a blood glucose monitoring liquid packaging body that can be easily operated by the user is required.

According to an embodiment of the present invention, the purpose is to provide a blood glucose monitoring liquid packaging body, the container of which is covered by a cover film; and a blood glucose test kit including the blood glucose monitoring liquid packaging body. The purpose of another embodiment is that the blood glucose quality control liquid package can simultaneously store different Quality control fluid; and a blood glucose test kit comprising the aforementioned blood glucose quality control fluid package, which is convenient for users to use.

According to an embodiment of the present invention, there is provided a blood glucose monitoring solution package, which includes a container, a first blood glucose monitoring solution, and a covering film. The container defines a first accommodating space in which the first blood glucose monitoring solution is stored, and the cover film covers the surface opening of the first accommodating space of the container to seal the first blood glucose monitoring solution.

In one embodiment, the cover film includes a first pattern, and the first pattern is printed on the top surface of the cover film to indicate the type of the first blood glucose monitoring solution.

In one embodiment, the blood glucose monitoring solution package further includes a second blood glucose monitoring solution. The container further defines a second accommodating space, and the second blood sugar monitoring solution is stored in the second accommodating space, and the cover film further covers the surface opening of the second accommodating space of the container to seal the second blood sugar monitoring solution . The cover film includes a first pattern and a second pattern, the first pattern is printed on the top surface of the cover film to indicate the type of the first blood glucose monitoring solution, and the second pattern is printed on the top surface of the cover film, Used to indicate the type of the second blood glucose monitoring solution.

In one embodiment, the first accommodating space of the container includes: an extending wall, a bottom, and an abutting wall. The extension wall extends downwardly from the top surface of the container. The bottom is formed into a groove shape. The abutting wall is connected between the bottom and the extending wall, and is configured such that when an electrochemical test piece is inserted into the first accommodating space, a front end sidewall of the electrochemical test piece abuts against the abutting wall.

In one embodiment, the material of the cover film is a material that can seal the first blood glucose monitoring solution in a storage state, and can be punctured or punctured by an electrochemical test strip when the first blood glucose monitoring solution is to be used.

According to an embodiment of the present invention, a blood glucose test kit is provided, which includes a blood glucose quality tube liquid packaging body and an electrochemical test piece. The blood sugar monitoring solution package includes a container, a first blood sugar monitoring solution and a covering film. The container defines the first accommodating space. The first blood glucose monitoring solution is stored in the first accommodating space. The cover film covers the surface opening of the first accommodating space of the container to seal the first blood sugar monitoring solution. The covering film of the blood sugar monitoring solution package body and the material of the electrochemical test piece are respectively configured so that the covering film can seal the first blood glucose monitoring solution in the storage state, and can be electrochemically sealed when the first blood sugar monitoring solution is to be used. The material that the test piece punctures or punctures.

In one embodiment, the first accommodating space of the container of the blood sugar tube liquid package includes: an extension wall, a bottom, and an abutting wall. The extension wall extends downwardly from the top surface of the container. The bottom is formed into a groove shape. The abutting wall is connected between the bottom and the extending wall, and is configured such that when the electrochemical test piece is inserted into the first accommodating space, a front end sidewall of the electrochemical test piece abuts against the abutting wall.

In one embodiment, the width of a top of the electrochemical test strip is smaller than the width of a top side of the groove-shaped bottom.

In one embodiment, the cover film includes a first pattern, and the first pattern is printed on the cover film The top surface is used to indicate the type of the first blood glucose monitoring solution.

In one embodiment, the blood glucose test kit further includes a second blood glucose monitoring solution. The container further defines a second accommodating space. The second blood glucose monitoring solution is stored in the second accommodating space. The cover film further covers the surface opening of the second accommodating space of the container to seal the second blood sugar monitoring solution. The cover film includes a first pattern and a second pattern, the first pattern is printed on the top surface of the cover film to indicate the type of the first blood glucose monitoring solution, and the second pattern is printed on the top surface of the cover film, Used to indicate the type of the second blood glucose monitoring solution. The width between the two opposite sides of the extension wall is greater than the width of the two opposite sides of the bottom, and the abutting wall is in an inclined line shape on both sides of the first accommodating space or the second accommodating space. The width of a top end of the electrochemical test piece is smaller than the width of a groove-shaped top side of the bottom. When the electrochemical test piece is inserted into the first accommodating space or the second accommodating space, and is positioned deepest against the abutting wall, a top end of the electrochemical test piece can be located in the groove shape at the bottom.

As described above, according to an embodiment of the present invention, the container of the blood glucose test solution package is covered by a cover film, and the material of the cover film is capable of sealing the test control liquids during storage, and when the test control liquid is to be used, it can be Material punctured or punctured by an electrochemical test strip. Therefore, when the user needs the quality control fluid, the cover film can be punctured directly with the electrochemical test piece, and the quality control fluid can enter the flow channel of the electrochemical test piece, thereby simplifying the procedures and steps of the user's operation. In one embodiment, different spaces in the container of the blood sugar monitoring solution package store different blood sugar monitoring solutions, so the user only needs to carry one blood glucose monitoring solution package to use two different blood sugar monitoring solutions at the same time. , which is convenient for users to operate. In one embodiment, the width of the top of the electrochemical test piece is smaller than the width of the top side of the groove at the bottom of the first accommodating space or the second accommodating space; An accommodating space or a second accommodating space is abutted against the abutting wall, and when it is located at the deepest point, the top of the electrochemical test strip can be located in the groove of the bottom. Such a design can ensure that the quality control fluid can sufficiently enter the flow channel of the electrochemical test piece, thereby reducing the phenomenon of erroneous measurement.

100: Sensing System

110: Electrochemical test piece

11a: Reference electrode

11b: Working electrode

200: Electrochemical sensor

211: Touchpoints

212: Touchpoints

220: Reference voltage source

230: Current-voltage conversion circuit

240: Analog-to-digital conversion circuit

250: Processor

260: Monitor

270: Timer

290: Bottle

291: Quality Control Fluid

300: Blood glucose quality control liquid packaging

310: Container

320: cover film

321: The first pattern

322: Second Pattern

331: Extension Wall

332: Against the Wall

333: Bottom

334: Slot extension wall

335: Bottom

341: The first accommodation space

342: Second accommodation space

351: The first blood glucose quality control solution

352: Second Blood Glucose Control Solution

390: Hole

400: Blood Glucose Test Kit

410: Electrochemical test piece

411: Front side wall

412: Top

415: runner

420: Outer bag

FIG. 1 shows a schematic diagram of the conventional operation when using QC fluid for calibration.

FIG. 2 shows a perspective view of a blood glucose monitoring solution package according to an embodiment of the present invention.

FIG. 3 is a perspective view of the blood glucose measuring tube liquid packaging body of the embodiment of FIG. 2 after removing the cover film.

FIG. 4 is a schematic diagram showing the use state of the blood glucose test kit according to an embodiment of the present invention.

FIG. 5 is a schematic diagram showing the use state of the blood glucose test kit according to another embodiment of the present invention.

FIG. 6 is an enlarged schematic diagram showing the use state of the blood glucose test kit of the embodiment of FIG. 5 .

FIG. 7 is a schematic diagram showing the use state of the blood glucose test kit according to another embodiment of the present invention.

FIG. 2 shows a perspective view of a blood glucose monitoring solution package according to an embodiment of the present invention. FIG. 3 is a perspective view of the blood glucose measuring tube liquid packaging body of the embodiment of FIG. 2 after removing the cover film. As shown in FIGS. 2 and 3 , according to an embodiment of the present invention, the blood glucose monitoring solution package 300 includes a container 310 , a covering film 320 and a first blood glucose monitoring solution 351 . The container 310 defines a first accommodating space 341 , and the first blood glucose monitoring solution 351 is stored in the first accommodating space 341 . The cover film 320 covers the surface opening of the first accommodating space 341 or the second accommodating space 342 (as described later) of the container 310 to seal the first blood sugar tube The liquid 351 or the second blood glucose test liquid 352 (as described later), so that these test liquids do not leak out.

The cover film 320 is made of a material that can seal the QC fluids during storage, and can be punctured or punctured by an electrochemical test piece 410 when the QC fluids are to be used. For example, the material of the cover film 320 can be a metal foil, such as aluminum foil or copper foil. Therefore, when the user needs the quality control fluid, the cover film 320 can be directly punctured with the electrochemical test piece 110 , and the quality control fluid can enter the flow channel of the electrochemical test piece 110 , and then the electrochemical sensor 200 can be used. Carry out test and calibration procedures. As shown in FIG. 2 , after the cover film 320 is punctured, holes 390 will remain. When the user needs the quality control fluid again, the electrochemical test piece 110 can be directly inserted into the hole 390 without opening the bottle cap or squeezing the bottle body to let the quality control fluid drop into the electrochemical test piece 110 On the flow channel, the operation time and steps are greatly reduced.

In one embodiment, as shown in FIG. 3 , preferably, the container 310 further defines a second accommodating space 342 , and the blood glucose monitoring solution package 300 further includes a second blood glucose monitoring solution 352 . The second blood glucose monitoring solution 352 is different from the first blood glucose monitoring solution 351 and is stored in the second accommodating space 342 . With this design, the user only needs to carry one blood glucose quality control solution package 300 , and can use two or more types of quality control solution, which is convenient for the user to calibrate the electrochemical sensor 200 . In addition, in this embodiment, as shown in FIG. 2 , a first pattern 321 and a second pattern 322 different from the first pattern 321 are further printed on the cover film 320 to indicate the type of the quality control fluid. For example, when the first blood glucose monitoring solution 351 is a high blood glucose monitoring solution (GCH), the first pattern 321 may be a pattern displaying GCH text, and when the second blood glucose monitoring solution 352 is a low blood glucose monitoring solution (GCL), the second pattern 322 may be a pattern displaying GCL characters.

FIG. 4 is a schematic diagram showing the use state of the blood glucose test kit according to an embodiment of the present invention. As shown in FIG. 4 , the blood glucose test kit 400 includes a blood glucose quality tube liquid packaging body 300 and an electrochemical test strip 410 . The structure of the blood glucose monitoring liquid packaging body 300 of the present embodiment is similar to the embodiment of FIGS. 2 and 3 , so the same components use the same symbols, and the relevant descriptions thereof are omitted, and only at least one difference is described below. In the present embodiment, the materials of the cover film 320 of the blood glucose test liquid package 300 and the body of the electrochemical test strip 410 are respectively configured so that the cover film 320 can seal these test liquids in the storage state, and the use of the quality control A material that can be punctured or punctured by the electrochemical test strip 410 when it is in liquid state. For example, the material of the cover film 320 can be a metal foil, such as aluminum foil or copper foil. The material of the body of the electrochemical test piece 410 can be glass, glass fiber board, alumina ceramics, zirconia ceramics, polystyrene (PS), polyethylene terephthalate (PET), Polycarbonate resin (Polycarbonate, PC), polypropylene (Polypropylene, PP), polyethylene (polyethylene, PE), acrylonitrile-butadiene-styrene copolymer (Acrylonitrile-Butadiene-Styrene, ABS), poly ( Polyethersulfon, PES), polyimide (Polyimide, PI), polyetherimide (Polyetherimide, PEI), polyamide-imide (Polyamide-imide, PAI), thermoplastic elastomer (Thermoplastic, TPE), polyamide Lactic acid (polylactic acid, PLA), or a combination thereof, and the like.

In one embodiment, the first accommodating space 341 or the second accommodating space 342 of the container 310 includes an extending wall 331 , an abutting wall 332 and a bottom 333 . The extension wall 331 extends downward from the top surface of the container 310 , and the abutting wall 332 is connected between the bottom 333 and the extension wall 331 for inserting the electrochemical test strip 410 into the first accommodating space 341 or the second accommodating space 342 , the front end side of the electrochemical test strip 410 Wall 411 abuts against abutment wall 332 . In this embodiment, the bottom 333 forms a plane. In addition, the front end sidewall 411 of the electrochemical test piece 410 is in an inclined line shape, so that the width of the top end 412 of the electrochemical test piece 410 is smaller than the width of the main body of the electrochemical test piece 410 . Preferably, the shape formed by the extension wall 331, the abutting wall 332 and the bottom 333 roughly matches the shape of the front end side of the electrochemical test piece 410, so that the front end side wall 411 of the electrochemical test piece 410 is in use. Can be abutted against the abutment wall 332 . In one embodiment, the width between the two opposite sides of the extension wall 331 is greater than the width of the two opposite sides of the bottom 333 , and the abutting wall 332 forms an inclined line on both sides of the first accommodating space 341 or the second accommodating space 342 shape.

FIG. 5 is a schematic diagram showing the use state of the blood glucose test kit according to another embodiment of the present invention. The embodiment of FIG. 5 is similar to the embodiment of FIG. 4 , and therefore the same elements are assigned the same symbols, and the related descriptions thereof are omitted. As shown in FIG. 5 , in the present embodiment, the bottom 333 of the first accommodating space 341 or the second accommodating space 342 of the blood glucose tube liquid packaging body 300 is formed into a groove shape. In one embodiment, the bottom 333 includes a groove extending wall 334 and a bottom surface 335 . The bottom end of the abutting wall 332 is extended downward by the groove extending walls 334 , and the bottom surface 335 is connected between the groove extending walls 334 .

FIG. 6 is an enlarged schematic diagram showing the use state of the blood glucose test kit of the embodiment of FIG. 5 . As shown in FIG. 6 , the width of the top 412 of the electrochemical test strip 410 is smaller than the width of the top side of the groove of the bottom 333 . In this way, when the electrochemical test piece 410 is inserted into the first accommodating space 341 or the second accommodating space 342 and abuts against the abutting wall 332 , and is located at the deepest point, the top end 412 of the electrochemical test piece 410 can in the groove of the bottom 333 . In this embodiment, when the first blood glucose monitoring solution 351 or the second blood glucose monitoring solution 352 is about to be used up, the blood glucose monitoring solution can be concentrated in the groove of the bottom 333 Since the top 412 of the electrochemical test piece 410 can be located in the groove of the bottom 333 |, it can be ensured that the quality control fluid can sufficiently enter the flow channel 415 of the electrochemical test piece 410 . In this way, the phenomenon of measurement errors caused by too little or no quality control fluid in the flow channel 415 of the electrochemical test piece 410 is reduced.

FIG. 7 is a schematic diagram showing the use state of the blood glucose test kit according to another embodiment of the present invention. As shown in FIG. 7 , the blood glucose test kit 400 further includes an outer bag 420 . The outer bag 420 forms a sealed space, and the blood glucose monitoring liquid packaging body 300 is arranged in the sealed space of the outer bag 420 . Preferably, the gas in the sealed space is squeezed out. During the flight of the aircraft, the cabin pressure is lower than the pressure on the ground, and the air in the sealing body such as the blood glucose quality control liquid packaging body 300 and the outer bag 420 still maintains the pressure on the ground, resulting in a pressure difference, and the sealing body is removed. The contents are squeezed out. However, the gas in the outer bag 420 is squeezed out, which can prevent the outer bag 420 from expanding too much, and can also be used as a buffer between the blood glucose monitoring liquid packaging body 300 and the atmospheric pressure of the external environment, so as to avoid the blood glucose monitoring liquid packaging body The cover film 320 is ruptured due to the excessive pressure difference 300 . In one embodiment, preferably, the outer bag 420 can be a zipper bag. The zipper bag has the advantages of being easy to open and seal, so it is convenient for the user to use, and avoids the problem of liquid overflow when the cover film 320 is ruptured.

To sum up, according to an embodiment of the present invention, the container 310 of the blood glucose control fluid package 300 is covered by the cover film 320, and the material of the cover film 320 is capable of sealing the quality control fluids during storage, and needs to be used A material that can be punctured or punctured by an electrochemical test piece 110 when testing liquid. Therefore, when the user needs the quality control fluid, the cover film 320 can be punctured directly with the electrochemical test piece 110, so that the quality control fluid can enter the flow channel of the electrochemical test piece 110, which simplifies the operation procedure of the user. and steps. In one embodiment, different spaces in the container 310 of the blood glucose monitoring liquid package 300 store different blood glucose monitoring liquids, so the user only needs to carry one blood glucose monitoring liquid packaging body 300 to use two different blood glucose monitoring liquids at the same time. Quality control fluid, convenient for users to operate.

In one embodiment, the width of the top 412 of the electrochemical test piece 410 is smaller than the width of the top side of the groove of the bottom 333 of the first accommodating space 341 or the second accommodating space 342; When the first accommodating space 341 or the second accommodating space 342 abuts against the abutting wall 332 and is located at the deepest point, the top 412 of the electrochemical test strip 410 can be located in the groove of the bottom 333 . Such a design can ensure that the QC fluids can sufficiently enter the flow channel 415 of the electrochemical test strip 410, thereby reducing the phenomenon of wrong measurement.

320: cover film

331: Extension Wall

332: Against the Wall

333: Bottom

400: Blood Glucose Test Kit

410: Electrochemical test piece

411: Front side wall

412: Top

Claims (11)

A blood glucose monitoring solution package, comprising: a container defining a first accommodating space; a first blood glucose monitoring solution stored in the first accommodating space; and a covering film covering the container The surface opening of the first accommodating space is used to seal the first blood sugar measuring tube liquid. The blood sugar monitoring solution package according to claim 1, wherein the cover film includes a first pattern, and the first pattern is printed on the top surface of the cover film to mark the first blood sugar monitoring solution kind of. The blood sugar monitoring solution package according to claim 1, further comprising a second blood sugar monitoring solution, wherein the container further defines a second accommodating space, and the second blood sugar monitoring solution is stored in the second blood sugar monitoring solution. In the accommodating space, the cover film further covers the surface opening of the second accommodating space of the container to seal the second blood sugar tube liquid, and the cover film includes a first pattern and a second pattern, The first pattern is printed on the top surface of the cover film to indicate the type of the first blood sugar product, and the second pattern is printed on the top surface of the cover film to indicate the second blood sugar product Types of tube fluids, wherein the first accommodating space and the second accommodating space are different spaces, and the first blood glucose quality control fluid and the second blood glucose quality control fluid are different quality control fluids. The blood sugar tube liquid package according to claim 1, wherein the first accommodating space of the container comprises: an extension wall extending downward from the top surface of the container; a bottom formed in a groove shape; and an abutting wall, connected between the bottom and the extending wall, and configured such that when an electrochemical test piece is inserted into the first accommodating space, a front end sidewall of the electrochemical test piece abuts against the abutting wall on the wall. The blood sugar monitoring solution package according to any one of claims 1 to 4, wherein the covering film is made of a material that can seal the first blood sugar monitoring solution in a storage state, and the first blood sugar monitoring solution is to be used. A material that can be punctured or punctured by an electrochemical test strip when exposed to liquid. A blood glucose test kit, comprising: a blood glucose monitoring solution package, comprising: a container defining a first accommodating space; a first blood glucose monitoring liquid stored in the first accommodating space; and a cover film covering the surface opening of the first accommodating space of the container to seal the first blood sugar monitoring solution; and an electrochemical test strip, wherein the covering film of the blood sugar monitoring solution package And the material of the electrochemical test piece, respectively, the cover film can seal the first blood glucose test liquid in the storage state, and can be punctured by the electrochemical test sheet when the first blood sugar test liquid is to be used or punctured material. The blood glucose test kit according to claim 6, wherein the first accommodating space of the container of the blood glucose monitoring liquid package is defined by a plurality of defining portions, the defining portions comprising: an extension wall extending downward from the top surface of the container; a bottom part formed into a groove shape; and an abutting wall connected between the bottom part and the extension wall and configured to be used when the electrochemical test strip is inserted When in the first accommodating space, a front end side wall of the electrochemical test piece abuts on the abutting wall. The blood glucose test set according to claim 7, wherein the width of a top end of the electrochemical test strip is smaller than the width of a groove-shaped top side of the bottom. The blood sugar test kit according to claim 6, wherein the cover film includes a first pattern, and the first pattern is printed on the top surface of the cover film to indicate the type of the first blood glucose monitoring solution . The blood glucose test kit according to claim 7, further comprising a second blood glucose monitoring solution, wherein the container further defines a second accommodating space, and the second blood glucose monitoring solution is stored in the second accommodating space In the space, the cover film further covers the opening on the surface of the second accommodating space of the container to seal the second blood glucose monitoring solution, and the cover film includes a first pattern and a second pattern, the first A pattern is printed on the top surface of the cover film to indicate the type of the first blood glucose monitoring solution, and the second pattern is printed on the top surface of the cover film to indicate the second blood glucose monitoring solution kind of, Wherein, the first accommodating space and the second accommodating space are different spaces, and the first blood glucose measurement fluid and the second blood glucose measurement fluid are different quality control fluids, wherein the two extending walls The width between the opposite sides is greater than the width of the two opposite sides of the bottom, and the abutting wall is in the shape of an inclined line on both sides of the first accommodating space or the second accommodating space, and a top end of the electrochemical test piece is The width is smaller than the width of the groove-shaped top side of the bottom, and when the electrochemical test piece is inserted into the first accommodating space or the second accommodating space, and is pressed against the abutting wall In the deepest position, a top of the electrochemical test strip can be located in the groove shape of the bottom. The blood sugar test set according to claim 10, further comprising an outer bag forming a sealed space, and the blood sugar monitoring liquid packaging body is placed in the sealed space.

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