TWI762077B - Uric acid detection device - Google Patents

Abstract

The invention provides a uric acid detection device, which mainly includes a casing, a light-emitting unit, a light sensor and a processor. The housing includes a detection portion and a grip portion connected to each other. The processor accommodates the holding portion, and is electrically connected to the light-emitting unit and the light sensor. The detection part is respectively provided with a light-emitting unit and a light sensor corresponding to two opposite inner surfaces of a liquid channel. The processor drives the light-emitting unit to generate an emission light source, wherein the wavelength of the emission light source is between 200 and 450 nm. The emission light source is used for projecting on a solution to be tested, and a detection light source is generated. The light sensor is used for receiving the detection light source and converting the detection light source into a detection signal. The processor receives the detection signal from the light sensor, and determines whether the absorption rate at 290 nm of the detection light source is greater than the absorption rate at 260 nm, so as to determine whether the detection solution contains uric acid.

Description

Uric acid detection device

The invention relates to a uric acid detection device, which can quickly detect whether a solution to be tested contains uric acid.

Due to changes in eating habits, hyperuricemia has become one of the common civilization diseases of modern people. According to medical research reports, in addition to gout, hyperuricemia may also cause chronic diseases such as obesity, hyperlipidemia, diabetes, heart disease and cerebrovascular disease.

Uric acid is the final product of purine metabolism in the body. Generally speaking, the uric acid value per 100 ml of blood in men is above 7 mg, and when it is above 6 mg in girls, it is called hyperuricemia. Through the detection of uric acid, the real-time health status of an individual can be known, and the diet can be adjusted immediately to slow down the continuous increase of uric acid in the blood and reduce the probability of gout.

At present, the common uric acid detection methods are mainly blood test and urine test. Before blood test, the person to be tested must fast for 8-10 hours, and need to go to the hospital or medical center to use chemical reagents and photoelectric analysis to detect blood. Uric acid concentration. Urine testing requires the person to be tested to collect urine within 24 hours, and also needs to go to a hospital or medical center for testing.

The two traditional uric acid tests mentioned above lack immediateness, so most people only realize that their uric acid is too high when they have a gout attack. At this time, they can only take drugs to metabolize uric acid in the blood.

In order to solve the problems faced by the above-mentioned prior art, the present invention proposes a uric acid detection device, which can instantly know whether the uric acid in the urine of the test subject is too high, adjust the diet in real time, and then infer whether the uric acid in the blood is too high, and immediately Adjust your diet to reduce your chances of developing gout.

An object of the present invention is to provide a uric acid detection device, which mainly includes a casing, a light-emitting unit, a light sensor and a processor. The housing includes a detection portion and a grip portion connected to each other. The processor accommodates the holding portion and is electrically connected to the light-emitting unit and the light-sensing unit. The detection part is respectively provided with a light-emitting unit and a light sensor corresponding to two opposite inner surfaces of a liquid channel. The light-emitting unit is used to generate an emission light source with a wavelength of 200 to 450 nm, wherein the emission light source is used to project a solution to be tested. , to generate a detection light source (absorption light source). The light sensor is used for receiving the detection light source and converting the detection light source into a detection signal. The processor receives the detection signal from the light sensor, and determines whether the uric acid in the solution to be tested is too high from the 290nm and 260nm parts of the detection signal.

According to the embodiment of the present invention, the way for the processor to determine whether the uric acid in the solution to be tested is too high is as follows: determine whether the absorption rate of the detection light source at 290 nm is greater than the absorption rate of 260 nm by the detection signal; determine the absorption rate of the detection light source by the detection signal Whether the ratio of the absorptivity at 290nm to the absorptivity at 260nm is greater than a specific ratio; determine whether the difference between the absorbance at 290nm minus the absorbance at 260nm of the detection light source is greater than a specific difference value from the detection signal; The 290nm absorptivity and the 260nm absorptivity slope of the light source are judged; or the absolute value of the 290nm absorptivity and 260nm absorptivity of the detection light source can be judged from the detection signal. Build a look-up table to find out whether uric acid is too high.

According to an embodiment of the present invention, the processor further calculates the absorbance at 290 nm and 260 nm in the detection light source from the detection signal, and calculates the uric acid content in the solution to be tested from the absorbance at 290 nm and 260 nm.

According to an embodiment of the present invention, the uric acid detection device further includes a reflection unit for reflecting the detection light source, and the light sensor receives the detection light source reflected by the reflection unit.

According to an embodiment of the present invention, the uric acid detection device further includes a display unit electrically connected to the processor for displaying whether the solution to be tested contains uric acid.

According to an embodiment of the present invention, the uric acid detection device further includes at least one control interface electrically connected to the processor and the light-emitting unit, and used to control or activate the processor and the light-emitting unit.

According to an embodiment of the present invention, the display unit and the control interface are arranged on the surface of the casing.

According to an embodiment of the present invention, the display unit and the control interface are disposed on the surface of the grip portion.

According to an embodiment of the present invention, the uric acid detection device further includes a reflection unit, the reflection unit is used for reflecting the detection light source, and the light sensor receives the detection light source reflected by the reflection unit. The housing includes a detection part and a holding part which are connected to each other. The detection part forms a liquid channel to allow the solution to be tested to enter. The detection part is provided with a light-emitting unit and a light sensor corresponding to a first inner surface of the liquid channel. , the detection part is provided with a reflection unit corresponding to a second inner surface of the liquid channel, the first inner surface is opposite to the second inner surface, the holding part accommodates the processor, and the display unit and the control interface are arranged on the surface of the holding part .

According to an embodiment of the present invention, the uric acid detection device further includes a DC/DC conversion circuit. The DC/DC conversion circuit is used to convert an input voltage of a battery into a voltage used by the light emitting unit, the light sensor, the control interface, the processor and the display unit.

To sum up the above, the uric acid detection device of the embodiment of the present invention does not need to add any chemical reagents, and does not need to collect urine samples, as long as the uric acid detection device is used to detect the solution to be tested in the toilet after the user urinates. Complete the detection of uric acid in urine, so as to achieve the purpose of home health monitoring.

1: Uric acid detection device

11: Lighting unit

12: Light sensor

13: Processor

14: Display unit

15: Control interface

16: DC/DC conversion circuit

17: Battery

18: Reflective unit

21: Detection Department

211: Liquid channel

22: Grip

D: ruler diameter

m1, m2: slope

FIG. 1 is a functional block diagram of a uric acid detection device according to an embodiment of the present invention.

FIG. 2 is a perspective view of a uric acid detection device according to an embodiment of the present invention.

3A is a schematic cross-sectional view of a detection part of a uric acid detection device according to an embodiment of the present invention.

3B is a schematic cross-sectional view of a detection portion of a uric acid detection device according to another embodiment of the present invention.

4 is a graph showing the absorbance at 290 nm and 260 nm in the detection light source of the uric acid detection device according to the embodiment of the present invention.

Please refer to FIGS. 1 to 3A. FIG. 1 is a functional block diagram of a uric acid detection device according to an embodiment of the present invention, FIG. 2 is a perspective view of the uric acid detection device according to an embodiment of the present invention, and FIG. 3A is a uric acid detection device according to an embodiment of the present invention. A schematic cross-sectional view of the detection section. The uric acid detection device 1 includes a light-emitting unit 11, a light sensor 12, a processor 13, a display unit 14, a control interface 15, a DC/DC converter The circuit 16, the battery 17, and the casing (including the detection part 21 and the grip part 22 connected to each other). The light-emitting unit 11 and the light sensor 12 are arranged on the detection part 21 of the casing, and the processor 13 , the display unit 14 , the control interface 15 , the DC/DC conversion circuit 16 and the battery 17 are arranged on the holding part 22 of the casing. The light emitting unit 11 and the light sensor 12 are electrically connected to the processor 13 and the DC/DC conversion circuit 16 through wires. The processor 13 is electrically connected to the display unit 14 and at least one control interface 15 , and the DC/DC conversion circuit 16 is electrically connected to the battery 17 , the processor 13 , the display unit 14 and the control interface 15 .

Specifically, as shown in FIG. 2 and FIG. 3A, the detection part 21 is formed with a liquid channel 211 to allow the solution to be tested in the toilet to enter. The detection part 21 has a first inner surface and a second inner surface corresponding to the liquid channel 211. An inner surface is opposite to a second inner surface, eg, the lower inner surface and the upper inner surface. The first inner surface and the second inner surface are provided with a light-emitting unit 11 and a light sensor 12, the holding portion 22 accommodates the processor 13, and the display unit 14 and the control interface 15 (there are two control interfaces 151 and 152 in FIG. 3A ). ) is provided on the surface of the grip portion 22 . The diameter D of the liquid channel 211 is preferably 1-10 mm.

In use, after the user takes a bath in the toilet, the user can hold the holding part 22 of the uric acid detection device 1, put the detection part 21 on the toilet to contact the solution to be tested in the toilet, and after the solution to be tested enters the liquid channel 211, By pressing the control interface 15, the uric acid detection device 1 starts to detect the solution to be tested, so as to detect whether the uric acid in the user's urine is too high, or the amount of uric acid.

The light-emitting unit 11 is used for generating an emission light source, wherein the wavelength of the emission light source is between 200 and 450 nm, and the emission light source is used to project on the solution to be tested, and generate a detection light source. The light sensor 12 is used for receiving the detection light source and converting the detection light source into a detection signal. The processor 13 receives the detection signal from the light sensor 12, and determines whether the uric acid in the solution to be tested is too high from the 290 nm and 260 nm parts of the detection signal. In addition, the processor 13 further calculates the absorption rates at 290 nm and 260 nm in the detection light source from the detection signal, and calculates the absorption rate at 290 nm and 260 nm in the solution to be tested from the absorption rates at 290 nm and 260 nm. The uric acid content, the processor 13 may be a processor of the x86 series or the ARM architecture, or may be other types of processors. The display unit 14 is used to display whether the solution to be tested contains uric acid. The display unit 14 can be LCD, LED, electronic paper, buzzer, light signal, touch screen or other types of display units, and the present invention is not limited to this . The control interfaces 151 and 152 can be a power switch and a measurement activation switch respectively to control or activate the processor 13 and the light-emitting unit 11 , and the control interfaces 151 and 152 can be mechanical switches, capacitive switches or touch screens. The DC/DC conversion circuit 16 is used to convert the input voltage of the battery 17 (for example, using two 1.5V dry batteries connected in series, a single lithium battery or a mercury battery) into the light-emitting unit 11, the light sensor 12, the control The voltage used by the interface 15 , the processor 13 and the display unit 14 is, for example, converting 3V to 3.3V or 5V.

Please note that the light-emitting unit 11 may be composed of more than one light-emitting diode, a substrate and a lens, wherein the light-emitting diode is on the substrate, and the lens window is correspondingly disposed on the light-emitting diode, and receives the light emitted by the light-emitting diode. light source to form an emission light source. In addition, the light sensor 12 may be composed of one or more light receiving diodes (which can also be implemented by a CMOS sensor, a CCD sensor or a spectrum measuring device), a substrate and a lens, wherein the light receiving diodes The body is on the base plate, and the lens window is correspondingly arranged on the light-receiving diode, and receives the detection light source, so as to send the detection light source to the light-receiving diode.

Please refer to FIG. 3B , which is a schematic cross-sectional view of a detection portion of a uric acid detection device according to another embodiment of the present invention. Compared with the previous embodiment, the uric acid detection device 1 further includes a reflection unit 18 for reflecting the detection light source, and the light sensor 12 receives the detection light source reflected by the reflection unit 18 . The detection part 21 is provided with a light emitting unit 11 and a light sensor 12 corresponding to the first inner surface of the liquid channel 211 , and the detection part 21 is provided with a reflection unit 18 corresponding to the second inner surface of the liquid channel 211 . In addition, in this embodiment, the light-emitting diodes of the light-emitting unit 11 and the light-receiving diodes of the light sensor 12 are located on the same substrate and share the same lens window.

Please refer to FIG. 4 , which is a graph of the absorbance at 290 nm and 260 nm in the detection light source of the uric acid detection device according to the embodiment of the present invention. It can be known from FIG. 4 that when there is uric acid in the solution to be tested, the absorption rate at 260 nm will have a trough, and the absorption rate at 290 nm will have a peak. Therefore, the processor 13 determines whether the uric acid in the solution to be tested is too high. The high method can be at least one of the following: (1) Determine whether the absorption rate of the detection light source at 290 nm is greater than the absorption rate of 260 nm from the detection signal; (2) Determine the absorption rate of the detection light source at 290 nm and 260 nm from the detection signal Whether the ratio of the ratios is greater than a specific ratio; (3) Determine whether the difference between the absorption rate at 290 nm of the detection light source minus the absorption rate at 260 nm is greater than a specific difference value from the detection signal; (4) Determine the 290 nm detection light source from the detection signal or (5) judge the absolute value of the absorptivity at 290nm and the absorptivity at 260nm of the detection light source from the detection signal. A Look-up table is performed to determine if uric acid is too high.

It can be known from Figure 4 that when uric acid exists, the absorption rate of the detection light source at 290 nm is greater than that of the detection light source at 260 nm. Therefore, the absorption rate of the detection light source at 290 nm minus the absorption rate of the detection light source at 260 nm will be greater than 0, and The ratio of the absorption rate of the detection light source at 290 nm to the absorption rate of the detection light source at 260 nm is greater than 1. In addition, the slope m2 of the detection light source at 290+delta nm will be negative, and the slope m1 of the detection light source at 260+delta nm will be positive, where delta is a positive value approaching 0.

To sum up, when the prior art detects uric acid, there are the following technical problems: the user needs to fast for 8-10 hours before the test; the user must go to a professional medical unit for the test; the test needs to use chemical reagents with photoelectric analysis for detection; and The lack of immediate detection makes it difficult to monitor uric acid in real time to reduce the incidence of gout. Compared with the prior art, the uric acid detection device of the present invention The uric acid detection device of the present invention solves the above-mentioned technical problems. When the uric acid detection device of the present invention is used, it does not need to collect urine and does not need to be assigned to a specific professional medical unit, because the present invention directly submerges the detection part into the solution to be tested in the toilet to detect There is no need to add biochemical reagents, no stirring and no test paper, because when the present invention directly sinks the detection part into the solution to be tested in the toilet, the solution to be tested will naturally enter the liquid channel, and the detection method is not to let uric acid It reacts with the reagent, but directly judges according to the absorption rate of the detection light source at 290nm and 260nm; and can detect the level of uric acid in real time to remind the user to avoid gout, because the present invention is portable, and the detection part is directly connected. The solution to be tested can be detected by sinking into the toilet.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention. Modifications should be included within the scope of the patent application of the present invention.

1: Uric acid detection device

11: Lighting unit

12: Light sensor

13: Processor

14: Display unit

15: Control interface

16: DC/DC conversion circuit

17: Battery

21: Detection Department

22: Grip

Claims (10)

A uric acid detection device, comprising: a casing, including a detection part and a grip part connected to each other, the detection part forms a liquid channel to allow a solution to be tested to enter; a light-emitting unit to generate an emission light source , wherein the wavelength of the emission light source is between 200 and 450 nm, the emission light source is used to project on the solution to be tested, and generates a detection light source; a light sensor is used to receive the detection light source, and the detection light source Converted into a detection signal, wherein the detection part is respectively provided with the light-emitting unit and the light sensor corresponding to two opposite inner surfaces of the liquid channel; and a handler, wherein the holding part accommodates the handler, And the processor is electrically connected to the photo sensor, the photo sensor receives the detection signal, and determines whether the uric acid in the solution to be tested is too high from the 290nm and 260nm parts of the detection signal. The uric acid detection device according to claim 1, wherein the processor determines whether the uric acid in the solution to be tested is too high: judging from the detection signal whether the absorption rate at 290 nm of the detection light source is greater than the absorption rate at 260 nm; Judging from the detection signal whether the ratio of the absorption rate at 290 nm to the absorption rate at 260 nm of the detection light source is greater than a specific ratio; Judging from the detection signal whether the difference between the absorption rate at 290 nm minus the absorption rate at 260 nm of the detection light source is greater than A specific difference value; judged by the detection signal to determine the slope of the absorption rate at 290 nm and the absorption rate at 260 nm of the detection light source; or Determine the absolute value of the absorption rate at 290 nm and the absorption rate at 260 nm of the detection light source from the detection signal, and establish a look-up table (Look-up table) from different absolute value size distribution ranges to search to determine whether uric acid is too high. high. The uric acid detection device according to claim 1, wherein the processor further calculates the absorption rates at 290 nm and 260 nm in the detection light source from the detection signal, and calculates the absorption rate at 290 nm and 260 nm in the solution to be tested from the absorption rates at 290 nm and 260 nm. uric acid content. The uric acid detection device according to claim 1, further comprises a reflection unit for reflecting the detection light source, and the light sensor receives the detection light source reflected by the reflection unit. The uric acid detection device according to claim 1, comprising a display unit electrically connected to the processor for displaying whether the solution to be tested contains uric acid. The uric acid detection device according to claim 5, further comprising at least one control interface electrically connected to the processor and the light-emitting unit, and used to control or activate the processor and the light-emitting unit. The uric acid detection device according to claim 6, wherein the display unit and the control interface are disposed on the surface of the casing. The uric acid detection device according to claim 7, wherein the display unit and the control interface are disposed on the surface of the grip portion. The uric acid detection device as claimed in claim 7, further comprising: a reflection unit for reflecting the detection light source, and the light sensor for receiving the detection light source reflected by the reflection unit; wherein the housing comprises mutually connected a detection part and a holding part, the detection part forms a liquid channel to allow the solution to be tested to enter, the detection part is provided with the light-emitting unit and the light sensor corresponding to a first inner surface of the liquid channel , the detection part is provided with a second inner surface corresponding to the liquid channel In the reflection unit, the first inner surface is opposite to the second inner surface, the holding part accommodates the processor, and the display unit and the control interface are disposed on the surface of the holding part. The uric acid detection device according to claim 6, further comprising: a DC/DC conversion circuit for converting an input voltage of a battery into the light-emitting unit, the light sensor, the control interface, and the processor with the voltage used by the display unit.

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