TWI708619B - Active particle temperature difference slow release structure - Google Patents
Active particle temperature difference slow release structure Download PDFInfo
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- TWI708619B TWI708619B TW108132237A TW108132237A TWI708619B TW I708619 B TWI708619 B TW I708619B TW 108132237 A TW108132237 A TW 108132237A TW 108132237 A TW108132237 A TW 108132237A TW I708619 B TWI708619 B TW I708619B
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Description
本發明係有關一種微粒結構,特別是一種活性微粒溫差緩釋結構。 The present invention relates to a microparticle structure, especially a temperature difference slow-release structure of active microparticles.
按,一般市面常見的面膜或是藥用貼布甚至是其他需添加額外微粒塗層的布料,在使用上都是藉由保養塗層或是藥性塗層對所貼附的地方釋放其中的微粒分子,進而達到特定目的,例如保養保濕或醫療傷口等。 According to the common facial masks or medicinal patches on the market, or even other fabrics that require additional particle coatings, they use maintenance coatings or medicinal coatings to release the particles in the place where they are attached. Molecules to achieve specific purposes, such as maintaining moisture or medical wounds.
而上述釋放的方式或是時間都是固定時間固定方式,所謂的固定方式就是將面膜或是藥用貼布貼於患部後即可在固定時間內進行微粒的釋放,但釋放過程中所耗的時間是固定的,也就是從包裝袋中取出後即開始釋放其中的微粒分子,即便尚未貼附於患部,當置放一定的時間後則失效無法再用。 The above-mentioned release method or time is a fixed time fixed method. The so-called fixed method is to release the particles within a fixed time after the mask or medicinal patch is applied to the affected area, but the release process is consumed The time is fixed, that is, the particulate molecules in it will be released after being taken out of the packaging bag. Even if it has not been attached to the affected area, it will become invalid after a certain period of time.
是以,要如何解決上述之問題與缺失,即為本案之發明人與從事此行業之相關廠商所亟欲研究改善之方向所在者。 Therefore, how to solve the above-mentioned problems and deficiencies is the direction that the inventors of this case and the related manufacturers engaged in this industry urgently want to study and improve.
為改善上述之問題,本發明之主要目的在於提供一種一般狀態下不主動釋放填充物之活性微粒溫差緩釋結構。 In order to improve the above-mentioned problems, the main purpose of the present invention is to provide a temperature-difference slow-release structure of active particles that does not actively release the filler under normal conditions.
本發明之另一主要目的在於提供一種達到有效保存功效之活性微粒溫差緩釋結構。 Another main objective of the present invention is to provide a temperature-difference slow-release structure of active particles that achieves effective preservation.
為達上述之目的,本發明提供一種活性微粒溫差緩釋結構,其包含:一基材;一塗料層,設置於該基材一面上,該塗料層由複數微粒組成,該等微粒包含:一殼體,具有至少一容置空間;及一填充物,設置於該容置空間內。 In order to achieve the above objective, the present invention provides a temperature-difference slow-release structure of active particles, which comprises: a substrate; a coating layer disposed on one surface of the substrate, the coating layer is composed of a plurality of particles, and the particles include: a The shell has at least one accommodating space; and a filler arranged in the accommodating space.
在一實施例,該基材具有一第一面及一第二面,所述塗料層設置於該第一面。 In one embodiment, the substrate has a first surface and a second surface, and the coating layer is disposed on the first surface.
在一實施例,該第一面具有複數孔洞用以收納該塗料層。 In one embodiment, the first surface has a plurality of holes for receiving the paint layer.
在一實施例,該第一面的表面粗糙度RA為1~300μm。 In one embodiment, the surface roughness RA of the first surface is 1˜300 μm.
在一實施例,該第一面的孔隙率為10~50%。 In one embodiment, the porosity of the first surface is 10-50%.
在一實施例,該孔洞的孔隙大小為30~300μm。 In one embodiment, the pore size of the hole is 30-300 μm.
在一實施例,該塗料層的厚度為0.2~2mm。 In one embodiment, the thickness of the coating layer is 0.2-2 mm.
在一實施例,該殼體具有一工作溫度區間。 In one embodiment, the housing has an operating temperature range.
在一實施例,該工作溫度區間係為30℃~70℃。 In one embodiment, the operating temperature range is 30°C to 70°C.
在一實施例,該殼體係由脂質、脂肪酸、蠟、礦物油、甘油酯、聚矽氧烷或其任意組合。 In one embodiment, the shell system is composed of lipids, fatty acids, waxes, mineral oils, glycerides, polysiloxanes or any combination thereof.
藉由上述結構,在一些特定的狀況下,殼體才會產生變化,例如溶解或破裂,使填充物釋放出來產生效果,而在一般的狀態下,該殼體不會產生變化,確保填充物不會任意的釋放出來,藉此達到一般狀態下不主動釋放填充物,達到有效保存之功效。 With the above structure, under some specific conditions, the shell will change, such as dissolving or rupturing, so that the filling will be released to produce an effect. Under normal conditions, the shell will not change to ensure that the filling It will not be released arbitrarily, so as to achieve the effect of not actively releasing the filler under normal conditions and achieving effective preservation.
1:基材 1: substrate
11:第一面 11: First side
111:孔洞 111: Hole
12:第二面 12: Second side
2:塗料層 2: Paint layer
21:微粒 21: Particles
211:殼體 211: Shell
212:填充物 212: Filling
3:受體 3: receptor
第1圖為本發明之立體結構示意圖;第2A圖為本發明微粒之剖面示意圖;第2B圖為本發明微粒受到刺激狀態之剖面示意圖(一); 第2C圖為本發明微粒受到刺激狀態之剖面示意圖(二);第3A圖為本發明第一態樣之基材結合塗料層的剖面示意圖;第3B圖為本發明第一態樣之基材結合塗料層的剖面示意圖;第3C圖為本發明第一態樣之基材結合塗料層的剖面示意圖;第4A圖為本發明實際使用狀態示意圖(一);第4B圖為本發明實際使用狀態示意圖(二)。 Figure 1 is a schematic diagram of the three-dimensional structure of the present invention; Figure 2A is a schematic cross-sectional view of the particles of the present invention; Figure 2B is a schematic cross-sectional view of the particles of the present invention under stimulation (1); Figure 2C is a schematic cross-sectional view of the stimulated state of the particles of the present invention (2); Figure 3A is a schematic cross-sectional view of the substrate combined with the coating layer of the first aspect of the present invention; Figure 3B is the substrate of the first aspect of the present invention A schematic cross-sectional view of the combined coating layer; Figure 3C is a schematic cross-sectional view of the substrate combined with the coating layer of the first aspect of the present invention; Figure 4A is a schematic diagram of the actual use state of the present invention (1); Figure 4B is the actual use state of the present invention Schematic diagram (two).
本發明之上述目的及其結構與功能上的特性,將依據所附圖式之較佳實施例予以說明。 The above-mentioned objects and structural and functional characteristics of the present invention will be described based on the preferred embodiments of the accompanying drawings.
請參閱第1圖、第4A圖及第4B圖,係為本發明之立體結構示意圖、實際使用狀態示意圖(一)及(二),本發明主要包含兩大部分,分別為基材1及塗料層2,將塗料層2設置於該基材1其中一面上,之後將帶有塗料層2的那面貼於受體3上,而基材1的形狀沒有任何限制,可依據使用需求進行設計,如第4A圖的面膜或者第4B圖的繃帶都是可以任意實施規劃的。
Please refer to Figure 1, Figure 4A and Figure 4B, which are the three-dimensional schematic diagrams of the present invention and the schematic diagrams (1) and (2) of the actual use state. The present invention mainly includes two parts, namely the
請參閱第2A圖、第2B圖及第2C圖,係為本發明微粒之剖面示意圖、微粒受到刺激狀態之剖面示意圖(一)及(二),並與輔以參考第1圖、第4A圖及第4B圖,所述塗料層2主要包含複數微粒21,該微粒21包含一殼體211及至少一填充物212,所述殼體211內具有至少一容置空間,該填充物212設置於該容置空間中所述,殼體211係為脂質、脂肪酸、蠟、礦物油、甘油酯、聚矽氧烷或其任意組合,該填充物212則視需求而定,可為皮膚保養用的活性精華液或者醫療用途的消毒液或醫療藥劑等等。
Please refer to Fig. 2A, Fig. 2B and Fig. 2C, which are the cross-sectional schematic diagrams of the particles of the present invention, and the cross-sectional schematic diagrams of the irritated state of the particles (1) and (2), with supplementary reference to Figs. 1 and 4A As shown in Figure 4B, the
所述殼體211具有一工作溫度區間,該工作溫度區間係為30℃~70℃,當殼體211處於這個工作溫度區間內時,該殼體211會逐漸地溶解變薄,直到殼體211出現破洞使內部的填充物212釋出。
The
進一步的,殼體211除了上述的溫度方式產生破洞外,進一步的可以透過壓力變化的方式使殼體211產生破洞,例如對塗料層2進行按壓,致使殼體211因受力而產生破裂使填充物212釋出。
Further, in addition to the above-mentioned temperature method, the
也就是說,在一般不使用的狀態下,需要低溫保持及避免重壓,避免殼體211破裂導致填充物212釋出,而要進行使用時,可以透過上述溫度溶解或者加壓破裂任一方式或併行使填充物212釋出至受體3上,達到使用之目的。
In other words, in the state of general non-use, it is necessary to maintain low temperature and avoid heavy pressure to avoid the release of the
請參閱第3A圖、第3B圖及第3C圖,係為本發明第一、二及三態樣之基材結合塗料層的剖面示意圖,並輔以參考上述所有附圖,在為了達到一個特定目的下,就必須控制塗料的多寡(塗料層2的厚度),對此基材1也有相對應的態樣不同,而下述個實施例都具有相同的結構,所述基材1具有一第一面11及一第二面12,該塗料層2設置於第一面11上,該塗料層2的厚度為0.2mm~2mm。
Please refer to Fig. 3A, Fig. 3B and Fig. 3C, which are the cross-sectional schematic diagrams of the first, second, and third aspect of the substrate bonding coating layer of the present invention, supplemented with reference to all the above drawings, in order to achieve a specific For this purpose, it is necessary to control the amount of paint (the thickness of the paint layer 2). The
請參閱第3A圖,為基材1第一態樣的示意圖,在本實施態樣中,基材1的第一面11表面為非光滑平面,該第一面11表面粗糙度RA為1~300μm,在塗料層2塗佈於基材1時部分塗料就會滲入第一面11,透過這樣的結構,能確保塗料層2有效的附著在第一面11。
Please refer to Figure 3A, which is a schematic diagram of the first aspect of the
請參閱第3B圖,為基材1第二態樣的示意圖,在本實施態樣中,基材1的第一面11表面為光滑平面且具有若干孔洞111,該第一面11表面孔隙率為
10%~50%,孔隙大小為30μm~300μm,在塗料層2塗佈於基材1時部分塗料就會進入孔洞111,透過這樣的結構,能確保第一面11上有著更多塗料。
Please refer to Figure 3B, which is a schematic diagram of the second aspect of the
請參閱第3C圖,為基材1第三態樣的示意圖,在本實施態樣中,基材1的第一面11表面為非光滑平面且具有若干孔洞111,在塗料層2塗佈於基材1時部分塗料就會滲入第一面11及進入孔洞111,透過這樣的結構,能確保塗料層2有效且大量的附著在第一面11。
Please refer to Figure 3C, which is a schematic diagram of the third aspect of the
在上述的幾個實施例中,可以明白在使用相同數量(重量)的塗料時,第一面11的表面粗糙度RA、孔洞111的孔隙率及孔隙大小都會影響塗料層2的厚度,因此本發明在顧慮到各方面的均衡及最佳使用效果的考量下時,取得了上述數值較佳的範圍區間,表面粗糙度RA為10~100μm,孔洞111的孔隙率為10%~50%,孔洞111的孔隙大小為50μm~200μm,在上述的條件下,塗料層2的厚度就會控制在0.5mm~1mm,使整體(包含基材1及塗料層2)維持一個合理的厚度,更容易貼附於受體3(人體皮膚表面)上。
In the above several embodiments, it can be understood that when the same number (weight) of paint is used, the surface roughness RA of the
請再參閱第4A圖及第4B圖,為本發明實際使用狀態示意圖(一)及(二)並輔以參考上述全部圖示,在第4A圖中,基材1為面膜的形狀,塗料層2與受體3(面部)相接處,在基材1上製作了一個勾掛於耳部的勾口,藉此讓基材1更服貼於臉上;在第4B圖中,基材1為繃帶的形狀,在纏繞於受體3(四肢)會有產生拉扯及緊壓的效果,有助於前述填充物212釋出(請參閱第2B圖及第2C圖)。
Please refer to Figures 4A and 4B again, which are schematic diagrams (1) and (2) of the actual use state of the present invention, supplemented by reference to all the above figures. In Figure 4A, the
綜上所述,本發明具有下述優點:1、 常溫不會釋放填充物;2、 達到工作溫度區間時填充物會自動釋出; 3、 透過壓力使填充物釋出;4、 搭配基材使塗料釋放填充物效果更佳。 In summary, the present invention has the following advantages: 1. The filling material will not be released at room temperature; 2. The filling material will be automatically released when the working temperature range is reached; 3. Release the filler through pressure; 4. Match the substrate to make the paint release the filler better.
以上已將本發明做一詳細說明,惟以上所述者,僅為本發明之一較佳實施例而已,當不能限定本發明實施之範圍。即凡依本發明申請範圍所作之均等變化與修飾等,皆應仍屬本發明之專利涵蓋範圍。 The present invention has been described in detail above, but what is described above is only a preferred embodiment of the present invention, and should not limit the scope of implementation of the present invention. That is to say, all equal changes and modifications made in accordance with the scope of application of the present invention should still be covered by the patent of the present invention.
21:微粒 21: Particles
211:殼體 211: Shell
212:填充物 212: Filling
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006116752A2 (en) * | 2005-04-28 | 2006-11-02 | The Regents Of The University Of California | Compositions comprising nanostructures for cell, tissue and artificial organ growth, and methods for making and using same |
TWM454209U (en) * | 2012-11-26 | 2013-06-01 | Tci Co Ltd | Enteric-coated sustained-release particle |
CN103917253A (en) * | 2011-09-02 | 2014-07-09 | 布吕歇尔有限公司 | Wound dressing with an air permeable layer |
CN106102513A (en) * | 2014-01-24 | 2016-11-09 | 先锋医疗株式会社 | Skin masking material |
TW201831172A (en) * | 2018-04-02 | 2018-09-01 | 奧倫國際有限公司 | Temperature difference slow release structure of active particles capable of enhancing convenience and comfort during usage and achieving slow release effect |
TWM590038U (en) * | 2019-09-06 | 2020-02-01 | 奧倫國際有限公司 | Temperature difference slow release structure of active particles |
-
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Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006116752A2 (en) * | 2005-04-28 | 2006-11-02 | The Regents Of The University Of California | Compositions comprising nanostructures for cell, tissue and artificial organ growth, and methods for making and using same |
CN103917253A (en) * | 2011-09-02 | 2014-07-09 | 布吕歇尔有限公司 | Wound dressing with an air permeable layer |
TWM454209U (en) * | 2012-11-26 | 2013-06-01 | Tci Co Ltd | Enteric-coated sustained-release particle |
CN106102513A (en) * | 2014-01-24 | 2016-11-09 | 先锋医疗株式会社 | Skin masking material |
TW201831172A (en) * | 2018-04-02 | 2018-09-01 | 奧倫國際有限公司 | Temperature difference slow release structure of active particles capable of enhancing convenience and comfort during usage and achieving slow release effect |
TWM590038U (en) * | 2019-09-06 | 2020-02-01 | 奧倫國際有限公司 | Temperature difference slow release structure of active particles |
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