TWI696862B - Contact lens and contact lens product - Google Patents

Abstract

A contact lens is for slowing down the development of myopia. The contact lens includes an optical zone and at least one light-blocking annular zone, wherein the light-blocking annular zone is disposed around a center point of the contact lens. At least one of the optical region and the at least one light-blocking annular region includes a photochromic material. When the specific condition is satisfied, excessive lights penetrating therethrough can be avoided meanwhile the lights penetrating therethrough are sufficient, which can ease the photophobia problem and can further eliminate peripheral aberrations, so that the clarity and sharpness of the image of the field of view can be enhanced.

Description

Contact lenses and contact lens products

The present invention relates to a contact lens and a contact lens product, and particularly relates to a contact lens and a contact lens product which can control the light flux and improve the imaging quality.

The eye is the window of the soul, however, due to birth defects or acquired improper use, the proportion of the population with abnormal vision is gradually rising. Common vision problems include myopia, hyperopia, or astigmatism. In myopic patients, the image is focused on the retina due to the strong corneal diopter. In hyperopic patients, the image is focused on the retina due to the weak corneal refractive power. The curvature of the cornea surface in different areas is uneven or the cornea surface is uneven, so that the light cannot be accurately focused on the retina to form a clear image.

In order to correct the aforementioned vision problems, patients usually wear framed glasses or contact lenses. The framed glasses are not conducive to outdoor activities and hinder the appearance, so the wearers of contact lenses are gradually climbing.

However, the effect of conventional contact lenses on luminous flux control is not good. Too much luminous flux can easily lead to photophobia problems. Too little luminous flux will cause the image to be dark and unclear. Therefore, how to improve the structure and/or material of contact lenses to effectively control the luminous flux, In other words, on the one hand, it can avoid excessive light entering the eyes to avoid photophobia, on the other hand, it can maintain sufficient luminous flux to ensure the brightness of the image, and it has become the goal of the efforts of relevant practitioners and scholars.

An object of the present invention is to provide a contact lens, which includes a light-blocking ring type region, thereby avoiding excessive light entering and taking into account sufficient light flux, which can reduce the photophobia problem, and can further eliminate peripheral aberrations, and Improve the clarity and sharpness of the image in the field of view.

0.24。 According to the present invention, a contact lens is provided, wherein the contact lens is a multifocal contact lens for slowing myopia. The contact lens includes an optical zone and at least one light-blocking ring zone, and the light-blocking ring zone is disposed around the center point of the contact lens. At least one of the optical zone and the light-blocking ring zone includes a photochromic material. The average transmittance of the light-blocking area in visible light is Tavg, the minimum diameter of the light-blocking area is CDmin, and the maximum diameter of the contact lens is D, which meets the following conditions: 0%<Tavg<50%; and CDmin/D

0.24.

According to the present invention, another contact lens product is provided, comprising the aforementioned contact lens and an infiltration solution. The contact lens is immersed in the infiltration solution. At least one of the contact lens and the infiltration solution includes a ciliary muscle paralysis agent.

According to the present invention, there is further provided a contact lens product, comprising the aforementioned contact lens and an infiltration solution, the contact lens is immersed in the infiltration solution, and at least one of the contact lens and the infiltration solution includes a muscarinic receptor blocking drug.

0.24；以及CDmax/D

0.89。 According to the present invention, a contact lens is further provided, which includes an optical zone and at least one light-blocking ring-shaped zone. The light-blocking ring-shaped zone is disposed around the center point of the contact lens. The minimum diameter of the light-blocking area is CDmin, the maximum diameter of the light-blocking area is CDmax, and the maximum diameter of the contact lens is D, which meets the following conditions: CDmin/D

0.24; and CDmax/D

0.89.

According to the present invention, another contact lens product is provided, comprising the aforementioned contact lens and an infiltration solution, the contact lens is immersed in the infiltration solution, at least one of the contact lens and the infiltration solution includes a ciliary muscle paralysis agent, and a ciliary muscle paralysis agent is The contact lens or the weight percentage concentration in the infiltration solution is ConA, which satisfies the following conditions: 0.01%<ConA<0.5%.

0.24；以及CDmin/OD<1.0。 According to the present invention, a contact lens is further provided, which includes an optical zone and at least one light-blocking ring-shaped zone. The light-blocking ring-shaped zone is disposed around the center point of the contact lens. The minimum diameter of the light-blocking area is CDmin, the maximum diameter of the contact lens is D, and the maximum diameter of the optical area is OD, which satisfies the following conditions: CDmin/D

0.24; and CDmin/OD<1.0.

According to the present invention, there is further provided a contact lens product, comprising the aforementioned contact lens and an infiltration solution, the contact lens is immersed in the infiltration solution, at least one of the contact lens and the infiltration solution includes a ciliary muscle paralysis agent, and a ciliary muscle paralysis agent is The contact lens or the weight percentage concentration in the infiltration solution is ConA, which satisfies the following conditions: 0.01%<ConA<0.5%.

When the Tavg meets the above conditions, it can avoid excessive light entering and can take into account sufficient luminous flux, which can reduce the photophobia problem, and can further eliminate peripheral aberrations, and can improve the clarity and sharpness of the image in the field of view.

When the CDmin/D satisfies the above conditions, it can avoid the entry of too much light and take into account sufficient luminous flux, which can reduce the photophobia problem, and can further eliminate peripheral aberrations, and can improve the clarity and sharpness of the image in the field of view.

When CDmax/D satisfies the above conditions, the light-blocking ring area can produce an effect of increasing the pupil area in outdoor environments and reduce the damage of strong light outdoors.

When CDmin/OD satisfies the above conditions, it helps to maintain an appropriate amount of incoming light and can ensure a visual imaging effect with moderate brightness.

When ConA meets the above conditions, the ciliary muscle paralysis agent can be slowly released when wearing contact lenses, which helps to delay the effect of myopia, simplify the treatment procedure, and enable patients to have vision control functions by simply wearing contact lenses, or Sagittal muscle paralyzing agents can be effective when contact lenses are worn, effectively exerting an immediate effect and having a simplified treatment procedure.

10, 100, 200, 300, 400, 500, 600, 700, 800, 900, 1000, 1100, 1200, 1300 ‧‧‧ contact lenses

11, 110, 210, 310, 410, 510, 610, 710, 810, 910, 1010, 1110, 1210, 1310 ‧‧‧ optical zone

12, 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320

221, 721, 821

222, 722, 822

223, 723‧‧‧ Third Light Block

224‧‧‧ Fourth Light Block

1320a‧‧‧Mini Light Block

12A, 120A, 220A, 320A, 420A, 520A, 620A, 720A, 820A, 920A, 1020A, 1120A, 1220A, 1320A

O‧‧‧Center

20‧‧‧Wetting solution

30‧‧‧Contact lens products

CDmin‧‧‧Minimum diameter of light blocking ring area

CDmax‧‧‧Maximum diameter of light blocking ring area

OD‧‧‧Maximum diameter of optical zone

D‧‧‧Maximum diameter of contact lens

BC‧‧‧ contact lens base arc

The average transmittance of Tavg‧‧‧block ring area in visible light

Tavg1‧‧‧The average transmittance of the first light blocking part in visible light

Tavg2 The average transmittance of the second light-blocking part in visible light

Tavg3‧‧‧The average transmittance of the third light blocking part in visible light

Tavg4 The average transmittance of the fourth light blocking part in visible light

ConA‧‧‧Ciliary muscle paralysis agent in contact lenses or in infiltration solution

FIG. 1A is a schematic diagram illustrating a contact lens according to an embodiment of the present invention; FIG. 1B is a schematic diagram illustrating a side view of the contact lens in FIG. 1A; FIG. 2 is a schematic diagram illustrating another embodiment of the present invention. A schematic diagram of a contact lens product; FIG. 3 is a schematic diagram showing a contact lens according to Embodiment 1 of the present invention; FIG. 4 is a schematic diagram showing a contact lens according to Embodiment 2 of the present invention; FIG. 5 is a drawing A schematic diagram of a contact lens according to Embodiment 3 of the present invention; FIG. 6 is a schematic diagram of a contact lens according to Embodiment 4 of the present invention; FIG. 7 is a schematic diagram of a contact lens according to Embodiment 5 of the present invention FIG. 8 is a schematic diagram showing a contact lens according to Embodiment 6 of the present invention; FIG. 9 is a schematic diagram showing a contact lens according to Embodiment 7 of the present invention; FIG. 10 is a diagram showing implementation according to the present invention A schematic diagram of a contact lens of Example 8; FIG. 11 is a schematic diagram of a contact lens according to Embodiment 9 of the present invention; FIG. 12 is a schematic diagram of a contact lens according to Embodiment 10 of the present invention; FIG. 13 FIG. 14 is a schematic diagram showing a contact lens according to Embodiment 11 of the present invention; FIG. 14 is a schematic diagram showing a contact lens according to Embodiment 12 of the present invention; and FIG. 15 is a diagram showing a contact lens according to Embodiment 13 of the present invention Schematic diagram of contact lenses.

FIG. 1A is a schematic diagram illustrating a contact lens 10 according to an embodiment of the present invention. In FIG. 1A, the contact lens 10 includes an optical region 11 and a light-blocking ring region 12. The light-blocking ring region 12 is disposed around the center point O of the contact lens 10.

Specifically, in FIG. 1A, the optical area 11 refers to the area enclosed by the dotted line, and the light-blocking area 12 refers to the area at the sprinkling point. In this embodiment, the optical region 11 and the light-blocking ring region 12 partially overlap, but in other embodiments, the optical region 11 and the light-blocking ring region 12 may be completely staggered. In addition, the light-blocking ring region 12 may be concentric with the contact lens 10, and the light-blocking ring region 12 may also be non-concentric with the contact lens 10.

60%。藉此，可避免過多光線進入並可兼顧充足光通量，而可減輕畏光問題，並可進一步消除周邊像差，而可提升視野範圍內影像的清晰度和銳利度。或者，其可滿足下列條件：0%<Tavg50%。或者，其可滿足下列條件：1%<Tavg

50%。或者，其可滿足下列條件：0%<Tavg

40%。或者，其可滿足下列條件：5%<Tavg

40%。或者，其可 滿足下列條件：0%<Tavg

30%。或者，其可滿足下列條件：10%<Tavg

30%。或者，其可滿足下列條件：0%<Tavg

20%。或者，其可滿足下列條件：10%<Tavg

20%。或者，其可滿足下列條件：0%<Tavg

10%。 The average transmittance of the light-blocking ring region 12 in visible light (400 nm to 700 nm) is Tavg, which satisfies the following conditions: 0%<Tavg

60%. In this way, excessive light can be avoided and sufficient luminous flux can be taken into account, which can reduce the photophobia problem, and can further eliminate peripheral aberrations, and can improve the clarity and sharpness of the image in the field of view. Or, it can meet the following conditions: 0%<Tavg50%. Or, it can meet the following conditions: 1%<Tavg

50%. Or, it can meet the following conditions: 0%<Tavg

40%. Or, it can meet the following conditions: 5%<Tavg

40%. Or, it can meet the following conditions: 0%<Tavg

30%. Or, it can meet the following conditions: 10%<Tavg

30%. Or, it can meet the following conditions: 0%<Tavg

20%. Or, it can meet the following conditions: 10%<Tavg

20%. Or, it can meet the following conditions: 0%<Tavg

10%.

CDmin/D

0.80。藉此，可避免過多光線進入並可兼顧充足光通量，而可減輕畏光問題，並可進一步消除周邊像差，而可提升視野範圍內影像的清晰度和銳利度。或者，其可滿足下列條件：0.01

CDmin/D

0.45。或者，其可滿足下列條件：0.05

CDmin/D

0.45。或者，其可滿足下列條件：0.10

CDmin/D

0.40。或者，其可滿足下列條件：0.20

CDmin/D

0.40。 The minimum diameter of the light-blocking area 12 is CDmin, and the maximum diameter of the contact lens 10 is D, which satisfies the following conditions: 0.01

CDmin/D

0.80. In this way, excessive light can be avoided and sufficient luminous flux can be taken into account, which can reduce the photophobia problem, and can further eliminate peripheral aberrations, and can improve the clarity and sharpness of the image in the field of view. Or, it can meet the following conditions: 0.01

CDmin/D

0.45. Or, it can meet the following conditions: 0.05

CDmin/D

0.45. Or, it can meet the following conditions: 0.10

CDmin/D

0.40. Or, it can meet the following conditions: 0.20

CDmin/D

0.40.

The light-blocking ring region 12 may include at least two light-blocking portions (refer to FIG. 4), and there may be gaps between different light-blocking portions, or may be designed to be closely connected. In this way, the throughput of visible light can be further reduced, and the effect of reducing photophobia can be improved.

The average transmittance of the plurality of light-blocking parts of the light-blocking ring region 12 to visible light can be changed gradually, which means that different light-blocking parts can have different color depth design, and the color can be designed from inside to outside. Shallow (Tavg1<Tavg2, where Tavg1 and Tavg2 are the average transmittance of the first light blocking part and the second light blocking part from the inside to the visible light), or can be designed to be shallow to deep (Tavg1>Tavg2), If there are more light blocking parts, it can be further designed from deep to shallow to deep (Tavg1<Tavg2 and Tavg3<Tavg2, where Tavg1, Tavg2, Tavg3 are the first light blocking part, the second The average transmittance of the light-blocking portion and the third light-blocking portion in visible light) can also be a gradual change in the wave-like color depth from light to deep to light (Tavg1>Tavg2 and Tavg3>Tavg2). In this way, the effect of blocking visible light can be effectively changed and controlled, and the blocking range can be strengthened and the visual aesthetic effect can be taken into consideration with the gradual design.

The light blocking portion of the light blocking ring region may further include a plurality of micro light blocking portions (refer to FIG. 15), the micro light blocking portions may be arranged in a radial manner, and the average transmittance of the micro light blocking portions to visible light It can be a gradual change, which means that different micro-blocking parts can have different color depth changes along the clockwise direction or counterclockwise direction. In this way, the visual aesthetic effect can be enhanced and the rotation positioning recognition function can be provided.

CDmax-CDmin

13.0mm。藉此，阻光環型區12的大小適當，有助於提升視覺舒適性並符合美觀需求。或者，其可滿足下列條件：1.0mm

CDmax-CDmin

12.0mm。或者，其可滿足下列條件：1.5mm

CDmax-CDmin

11.0mm。或者，其可滿足下列條件：2.0mm

CDmax-CDmin

10.0mm。或者，其可滿足下列條件：3.0mm

CDmax-CDmin

9.0mm。或者，其可滿足下列條件：3.0mm

CDmax-CDmin

8.0mm。 The maximum diameter of the light blocking ring region 12 is CDmax, and the minimum diameter of the light blocking ring region 12 is CDmin, which can satisfy the following conditions: 0.5mm

CDmax-CDmin

13.0mm. In this way, the size of the light blocking ring region 12 is appropriate, which helps to improve visual comfort and meet aesthetic requirements. Or, it can meet the following conditions: 1.0mm

CDmax-CDmin

12.0mm. Or, it can meet the following conditions: 1.5mm

CDmax-CDmin

11.0mm. Or, it can meet the following conditions: 2.0mm

CDmax-CDmin

10.0mm. Or, it can meet the following conditions: 3.0mm

CDmax-CDmin

9.0mm. Or, it can meet the following conditions: 3.0mm

CDmax-CDmin

8.0mm.

CDmin/OD

2.0。藉此，有助於維持適當的進光量，可確保明暗度適中的視覺成像效果。或者，其可滿足下列條件：0.10

CDmin/OD

1.80。或者，其可滿足下列條件：0.15

CDmin/OD

1.60。或者，其可滿足下列條件：0.15

CDmin/OD

1.40。或者，其可滿足下列條件：0.20

CDmin/OD

1.00。或者，其可滿足下列條件：0.20

CDmin/OD

0.85。 The minimum diameter of the light blocking ring region 12 is CDmin, and the maximum diameter of the optical region 11 is OD, which can satisfy the following conditions: 0.05

CDmin/OD

2.0. In this way, it helps to maintain an appropriate amount of incoming light and can ensure a visual imaging effect with moderate brightness. Or, it can meet the following conditions: 0.10

CDmin/OD

1.80. Or, it can meet the following conditions: 0.15

CDmin/OD

1.60. Or, it can meet the following conditions: 0.15

CDmin/OD

1.40. Or, it can meet the following conditions: 0.20

CDmin/OD

1.00. Or, it can meet the following conditions: 0.20

CDmin/OD

0.85.

In this embodiment, the inner periphery 12A of the light-blocking ring region 12 is circular. In other embodiments, the inner periphery 12A of the light-blocking ring region 12 may be a polygon with at least four sides (refer to FIGS. (Figure 10). In this way, diversified changes can be designed according to consumer needs to avoid monotonous patterns, and can also provide confirmation and identification of astigmatism correction, presbyopia correction or the rotation stabilization direction of multifocal lenses.

The contact lens 10 may include photochromic materials, thereby helping to reduce the irritation and damage to eyes caused by strong light in an outdoor strong light environment, and can enhance the visible light blocking and insulating effect of the light blocking ring type area 12 to improve Applicability of the environment where the intensity of the light source changes drastically.

The photochromic material refers to a substance (A) that when irradiated with light of a certain wavelength will undergo a chemical reaction and be transformed into another substance (B), and the generated another substance (B) is in the light or heat Under the action, a reversible chemical reaction will occur to return to the original substance (A). The absorption spectrum of the original substance (A) and another substance (B) are different and show different colors. Specifically, the photochromic material may be, but not limited to, spiropyrans, spirooxazines, benzo and naphthopyrans, and Fulgides, diarylethenes or combinations thereof. The aforementioned "combination" means that the photochromic material may include spiropyran compounds, spiro 1,4-oxanitrohexanyl compounds, naphthopyran compounds, spermic acid anhydride compounds, and diarylvinyl compounds At least two of them can be mixed in any ratio. For example, spiropyrans may be, but not limited to, 1 ' , 3' -dihydro-1 ' , 3 ' , 3' -trimethyl-6-nitrospiro[2H-1-benzopyran -2,2 ' -(2H)-indole](1 ' ,3 ' -dihydro-1 ' ,3 ' ,3 ' -trimethyl-6-nitrospiro[2H-1-benzopyran-2,2 ' -(2H )-indole]; CAS No. 1498-88-0) or 1 ' ,3 ' -dihydro-8-methoxy-1 ' ,3 ' ,3 ' -trimethyl-6-nitrospiro[2H -1-benzopyran-2,2 ' -(2H)-indole](1 ' ,3 ' -dihydro-8-methoxy-1 ' ,3 ' ,3 ' -trimethyl-6-nitrospiro[2H- 1-benzopyran-2,2 ' -(2H)-indole]; CAS number is 1498-89-1). Spiro 1,4-oxazepine compounds can be, but not limited to, 1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3 ' -[3H]naphtho[ 2,1-b][1,4]azine](1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3 ' -[3H]naphth[2,1-b][1 ,4]oxazine]; CAS No. 27333-47-7) or 5-chloro-1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3 ' -(3H ) Naphtho[2,1-b](1,4)azine](5-chloro-1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3 ' -(3H)naphth[ 2,1-b](1,4)oxazine]; CAS No. 27333-50-2) or 1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3 ' -[3H]phenanthro[9,10-b](1,4)azine](1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3 ' -[3H]phenanthro[ 9,10-b](1,4)oxazine]; CAS No. 119980-36-8). The naphthopyran compound may be, but not limited to, hydroxy-4-methyl-2H-naphtho(1,2-B)pyran-2-one (hydroxy-4-methyl-2H-naphtho(1,2- B) pyran-2-one; CAS number 21353-16-2). The sperm anhydride compounds can be, but not limited to, (E)-benzylidene (diphenylmethylene) succinic anhydride ((E)-benzylidene (diphenylmethylene) succinic anhydride; CAS number 37460-01-8) or 3- [(E)-2-(2,5-Dimethylfuran-3-yl)ethylene]dihydro-4-(1-methylethylene)-2,5-furandione (3- [(E)-2-(2,5-dimethylfuran-3-yl)ethylidene]dihydro-4-(1-methylethylidene)-2,5-furandione; CAS No. 77515-04-9). The diarylvinyl compound may be, but not limited to, 9,10-dihydrophenanthrene (CAS number 776-35-2).

Specifically, at least one of the optical region 11 and the light-blocking ring region 12 may include photochromic materials, that is, only the optical region 11 may include photochromic materials, or only the light blocking ring region 12 may include photochromic materials. Or, the optical region 11 and the light-blocking ring region 12 include photochromic materials at the same time. When the optical zone 11 contains a photochromic material, the contact lens 10 can function like a sunglass in an outdoor environment with strong light, reducing the irritation and damage to eyes caused by strong light. When the light-blocking ring area 12 includes a photochromic material, the visible light blocking and blocking effect of the light-blocking ring area 12 can be enhanced, which can be effectively used indoors or outdoors, and improves the environmental applicability of the light source intensity changes drastically.

More specifically, the photochromic material can be added to the composition for making the contact lens 10, whereby the entire contact lens 10 has a photochromic effect. Alternatively, the photochromic material may be added only to a part of the contact lens 10. For example, the contact lens 10 may be a double-layer contact lens adopting a sandwich process. The double-layer contact lens includes an object side layer (not shown) and an image side Layer (not shown) has two main structures, and the object side layer and the image side layer have color films (not shown). The color film can be formed on the object side layer and the image side layer by printing, evaporation, coating, etc. On the surface, and the color film can be formed on specific areas on the surfaces of the object-side layer and the image-side layer and can have different pattern changes. At this time, the photochromic material can be added to the object-side layer and/or the image-side layer For example, it can be blended into the composition of the object-side layer and/or the image-side layer, so that the object-side layer and/or the image-side layer as a whole have a photochromic effect, or the photochromic material can be printed or evaporated , Coating and other methods are formed on the surface of the object-side layer and/or image-side layer (which can be partially or completely covered), or the photochromic material can be added to the color pigments forming the color film to become part of the color film The specific blocks formed on the surfaces of the object-side layer and the image-side layer may have different pattern changes.

The material of the contact lens 10 may be silicone glue, and the composition for preparing the silicone glue may include at least three monomers, and the monomers may be 2-hydroxyethyl methacrylate and methacrylic acid. , 2-methyl-2-acrylic acid-2,3-dihydroxypropyl (glycerol monomethacrylate), N-vinyl-2-pyrrolidinone (N-vinyl-2-pyrrolidinone), N,N-dimethylpropene N,N-dimethyl acrylamide, 3-methacryloyloxypropyltris (trimethylsilyloxy)silane, (3-methacryloyloxy-2 -Hydroxypropoxy)propyl bis(trimethylsiloxy)methyl (3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane), 3-acetoxy-2-hydroxypropoxy Propyl-terminated polydimethylsiloxane ((3-acryloxy-2-hydroxypropoxypropyl) terminated polydimethylsiloxane) or methyl methacrylate, which means that at least three of the aforementioned monomers can be selected as the preparation silicon The monomer component in the hydrogel composition, other components of the silicone hydrogel composition are conventional, and will not be repeated here. In this way, the contact lens 10 has a better oxygen permeability and can provide a comfortable wearing feeling for a long time.

The material of the contact lens 10 may be hydrogel, and the composition for preparing the hydrogel may include at least two monomers, and the monomers may be hydroxyethyl methacrylate, methacrylic acid, 2-methyl-2-acrylic acid-2 ,3-dihydroxypropyl ester, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide or methyl methacrylate, which means that at least two of the aforementioned monomers can be selected as the preparation water The monomer component in the glue composition, other components of the water glue composition are conventional, and will not be repeated here. In this way, the contact lens 10 has better moisture content and comfort, can maintain the moist, smooth and soft and comfortable moist feeling of the contact lens 10, and avoid foreign body sensation when wearing.

The contact lens 10 may be a multifocal contact lens. In this way, it is helpful to correct astigmatism, presbyopia, myopia and hyperopia. When applied to correct myopia, it can further provide vision control effects that reduce myopia.

CDmax/D

1.0。藉此，阻光環型區12可於戶外環境下產生增大瞳孔面積的效果，並減緩於戶外的強光傷害。或者，其可滿足下列條件：0.55

CDmax/D

1.00。或者，其可滿足下列條件：0.65

CDmax/D

1.00。或者，其可滿足下列條件：0.75

CDmax/D

1.00。或者，其可滿足下列條件：0.80

CDmax/D

0.95。 The maximum diameter of the light-blocking area 12 is CDmax, and the maximum diameter of the contact lens 10 is D, which can satisfy the following conditions: 0.5

CDmax/D

1.0. In this way, the light-blocking ring-shaped area 12 can produce an effect of increasing the pupil area in an outdoor environment, and reduce the damage of strong light outdoors. Or, it can meet the following conditions: 0.55

CDmax/D

1.00. Or, it can meet the following conditions: 0.65

CDmax/D

1.00. Or, it can meet the following conditions: 0.75

CDmax/D

1.00. Or, it can meet the following conditions: 0.80

CDmax/D

0.95.

BC。藉此，隱形眼鏡10可提供曲率半徑較大的基弧，有助於服貼於較平整的角膜，而可提升配戴舒適性與貼服度。例如，進行過雷射角膜手術後的患者，由於角膜經手術切除後較為平整，一般隱形眼鏡的基弧無法達到有效的舒適性與完整貼服度，因此本發明的隱形眼鏡10有利於進行過雷射角膜手術後的患者配戴。或者，其可滿足下列條件：9.25mm

BC。或者，其可滿足下列條件：9.50mm

BC。或者，其可滿足下列條件：9.75mm

BC。或者，其可滿足下列條件：10.00mm

BC

100.00mm。 Please refer to FIG. 1B, which is a schematic side view of the contact lens 10 in FIG. 1A. In FIG. 1B, the base curve of the contact lens 10 is BC, which can satisfy the following conditions: 9.00mm

BC. In this way, the contact lens 10 can provide a base arc with a larger radius of curvature, which helps to adhere to a flat cornea, and can improve wearing comfort and conformability. For example, in patients who have undergone laser corneal surgery, since the cornea is relatively flat after surgery, the base arc of general contact lenses cannot achieve effective comfort and complete fit, so the contact lens 10 of the present invention is beneficial for Patient wear after laser corneal surgery. Or, it can meet the following conditions: 9.25mm

BC. Or, it can meet the following conditions: 9.50mm

BC. Or, it can meet the following conditions: 9.75mm

BC. Or, it can meet the following conditions: 10.00mm

BC

100.00mm.

Specifically, the base arc refers to the curvature of the rear surface (not otherwise labeled) of the contact lens 10 close to the cornea. A larger base arc means that the rear surface of the contact lens 10 is flatter. When the base arc of the contact lens 10 is larger than the base arc of the eyeball, the contact lens 10 cannot lie on the surface of the eyeball and displacement problems easily occur. On the contrary, the base of the contact lens 10 If the arc is smaller than the base arc of the eyeball, it is easy to produce excessive tension and discomfort. Therefore, when the base arc of the contact lens 10 is very different from the base arc of the eyeball, it is easy to cause fluctuations in vision or the contact lens 10 to fall off, and even cause corneal infection. . Generally, the base arc of the contact lens 10 is about 0.4 mm larger than that of the cornea. The base arc of the Chinese eyeball is between 8.4 mm and 8.6 mm. Therefore, the base arc of contact lenses on the market is currently designed to be less than 9 mm. It is not suitable for patients with myopic laser surgery who have a flat cornea due to the operation.

FIG. 2 is a schematic diagram showing a contact lens product 30 according to another embodiment of the invention. In FIG. 2, the contact lens product 30 includes a contact lens 10 and an infiltration solution 20. The contact lens 10 is immersed in the infiltration solution 20. For the details of the contact lens 10, please refer to the foregoing, which will not be repeated here. The infiltration solution 20 may be a solution for soaking and preserving contact lenses on the market.

At least one of the contact lens 10 and the infiltration solution 20 may contain a ciliary muscle paralyzing agent. That is, only the contact lens 10 may contain the ciliary muscle paralyzing agent, or only the infiltration solution 20 may contain the ciliary muscle paralyzing agent, or the contact lens 10 and the infiltrating solution 20 may simultaneously contain the ciliary muscle paralyzing agent. In this way, the contact lens 10 of the present invention can improve the problem of peripheral aberrations and blurred images caused by pupil dilation caused by the ciliary muscle paralysis agent when using the ciliary muscle paralysis agent. Due to the action of the ciliary muscle paralysis agent, the pupil It is enlarged to 2 to 4 times the size of the original pupil. The pupil enlargement causes too much light in the peripheral area to enter the eye, which obviously interferes with and creates aberrations in the periphery. Therefore, the contact lens 10 of the present invention can block excessive light from entering and Take into account sufficient luminous flux to avoid serious photophobia problems, further effectively eliminate peripheral aberrations, and ensure the clarity and sharpness of the image within the field of view.

1%。或者，其可滿足下列條件：0%<ConA

0.5%。或者，其可滿足下列條件：0%<ConA

0.25%。或者，其可滿足下列條件：0%<ConA

0.1%。或者，其可滿足下列條件：0%<ConA

0.05%。或者，其可滿足下列條件：0%<ConA

0.01%。 Specifically, the ciliary muscle paralysis agent can be added to the composition for preparing the contact lens 10, and the finally formed contact lens 10 contains the ciliary muscle paralysis agent, whereby the contact lens 10 can be slowly released when worn The ciliary muscle paralysis agent helps to delay the effect of myopia, simplifies the treatment procedure and enables the patient to have the vision control function by simply wearing the contact lens 10. Alternatively, the ciliary muscle paralyzing agent may be added to a solution for immersing and preserving contact lenses on the market, so that the infiltrating solution 20 contains the ciliary muscle paralyzing agent, whereby the ciliary muscle paralyzing agent can be used when the contact lens 10 is worn It can produce effects, effectively exert immediate effects and have the function of simplifying treatment procedures. The concentration percentage of ciliary muscle paralysis agent in contact lens 10 or in infiltration solution 20 is ConA, which can satisfy the following conditions: 0%<ConA

1%. Or, it can meet the following conditions: 0%<ConA

0.5%. Or, it can meet the following conditions: 0%<ConA

0.25%. Or, it can meet the following conditions: 0%<ConA

0.1%. Or, it can meet the following conditions: 0%<ConA

0.05%. Or, it can meet the following conditions: 0%<ConA

0.01%.

According to the above description, specific embodiments are presented below and explained in detail in conjunction with the drawings.

<Example 1>

FIG. 3 is a schematic diagram showing a contact lens 100 according to Embodiment 1 of the present invention. In FIG. 3, the contact lens 100 includes an optical region 110 and a light blocking ring region 120. The light blocking ring region 120 is disposed around the center point 0 of the contact lens 100, and the inner peripheral edge 120A of the light blocking ring region 120 is circular. The optical zone 110 is an area enclosed by a dotted line. In Embodiment 1, the optical zone 110 partially overlaps with the light-blocking ring zone 120.

In Example 1, the minimum diameter of the light blocking ring region 120 is CDmin, the maximum diameter of the light blocking ring region 120 is CDmax, the maximum diameter of the optical region 110 is OD, the maximum diameter of the contact lens 100 is D, and the base of the contact lens 100 is The arc is BC (refer to FIG. 1A), and the values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 1 are recorded in Table 1.

The material of the contact lens 100 is hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate, methacrylic acid, 2-methyl-2-acrylic acid-2,3-dihydroxypropyl ester and N -Vinyl-2-pyrrolidone. The contact lens 100 is a single focus contact lens.

The average transmittance of the light-blocking ring region 120 to visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 2.

<Example 2>

FIG. 4 is a schematic diagram illustrating a contact lens 200 according to Embodiment 2 of the present invention. In FIG. 4, the contact lens 200 includes an optical region 210 and a light-blocking ring region 220. The light-blocking ring region 220 is disposed around the center point O of the contact lens 200, and the inner periphery 220A of the light-blocking ring region 220 is circular. Specifically, the light-blocking ring region 220 includes four unconnected light-blocking portions, namely a first light-blocking portion 221, a second light-blocking portion 222, a third light-blocking portion 223, and a fourth light-blocking portion 224. The optical zone 210 is an area enclosed by a dotted line. In Embodiment 2, the optical zone 210 and the light-blocking ring zone 220 partially overlap.

The values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 2 are recorded in Table 3. For the definition of the aforementioned parameters, please refer to Example 1.

The material of the contact lens 200 is hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate, methacrylic acid, and 2-methyl-2-acrylic acid-2,3-dihydroxypropyl ester. The contact lens 200 is a single focus contact lens.

The average transmittance of the light-blocking ring region 220 to visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 4.

In addition, in Embodiment 2, the average transmittance of the first light blocking portion 221, the second light blocking portion 222, the third light blocking portion 223, and the fourth light blocking portion 224 in visible light may be different from inside to outside, In Embodiment 2, the average transmittance of the first light blocking portion 221 in visible light is Tavg1, the average transmittance of the second light blocking portion 222 in visible light is Tavg2, and the average transmittance of the third light blocking portion 223 in visible light is The rate is Tavg3, and the average transmittance of the fourth light blocking portion 224 in visible light is Tavg4, where Tavg1>Tavg2>Tavg3>Tavg4. In Table 4, the value of Tavg is the minimum average transmittance among different light blocking parts (221-224), which means that the light blocking part (at least one of 221-224) has the best light blocking effect. In other words, in Example 2, Tavg=Tavg4.

<Example 3>

FIG. 5 is a schematic diagram illustrating a contact lens 300 according to Embodiment 3 of the present invention. In FIG. 5, the contact lens 300 includes an optical region 310 and a light blocking ring region 320. The light blocking ring region 320 is disposed around the center point O of the contact lens 300, and the inner periphery 320A of the light blocking ring region 320 is circular. The optical zone 310 is an area enclosed by a dotted line. In Embodiment 3, the optical zone 310 and the light-blocking ring zone 320 partially overlap.

The values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 3 are recorded in Table 5. For the definition of the aforementioned parameters, please refer to Example 1.

The material of the contact lens 300 is hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate and methacrylic acid. The contact lens 300 is a multifocal contact lens.

The average transmittance of the light-blocking ring region 320 to visible light is Tavg. The values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 6.

<Example 4>

FIG. 6 is a schematic diagram illustrating a contact lens 400 according to Embodiment 4 of the present invention. In FIG. 6, the contact lens 400 includes an optical region 410 and a light blocking ring region 420. The light blocking ring region 420 is disposed around the center point O of the contact lens 400, and the inner peripheral edge 420A of the light blocking ring region 420 is circular. The optical zone 410 is an area enclosed by a dotted line. In Embodiment 4, the optical zone 410 partially overlaps with the light-blocking ring zone 420.

The values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 4 are recorded in Table 7. For the definition of the aforementioned parameters, please refer to Example 1.

The material of the contact lens 400 is hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate and 2-methyl-2-acrylic acid-2,3-dihydroxypropyl ester. The contact lens 400 is a multifocal contact lens, and the contact lens 400 includes a ciliary muscle paralysis agent.

The average transmittance of the light-blocking ring region 420 to visible light is Tavg. The values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 8.

<Example 5>

FIG. 7 is a schematic diagram illustrating a contact lens 500 according to Embodiment 5 of the present invention. In FIG. 7, the contact lens 500 includes an optical region 510 and a light-blocking ring region 520. The light-blocking ring region 520 is disposed around the center point O of the contact lens 500, and the inner peripheral edge 520A of the light-blocking ring region 520 is a decagon. The optical zone 510 is an area enclosed by a dotted line. In Embodiment 5, the optical zone 510 and the light-blocking ring zone 520 partially overlap.

The values of the CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 5 are recorded in Table 9. For the definition of the aforementioned parameters, please refer to Example 1.

The material of the contact lens 500 is hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate and N-vinyl-2-pyrrolidone. The contact lens 500 is a single focus contact lens.

The average transmittance of the light-blocking ring region 520 in visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 10.

<Example 6>

FIG. 8 is a schematic diagram illustrating a contact lens 600 according to Embodiment 6 of the present invention. In FIG. 8, the contact lens 600 includes an optical region 610 and a light-blocking ring region 620. The light-blocking ring region 620 is disposed around the center point 0 of the contact lens 600, and the inner peripheral edge 620A of the light-blocking ring region 620 is hexagonal. The optical zone 610 is an area enclosed by a dotted line. In Embodiment 6, the optical zone 610 partially overlaps with the light-blocking ring zone 620.

The values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 6 are recorded in Table 11. For the definition of the aforementioned parameters, please refer to Example 1.

The material of the contact lens 600 is hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate, 2-methyl-2-acrylic acid-2,3-dihydroxypropyl ester, and N-vinyl- 2-pyrrolidone. The contact lens 600 is a single-focus contact lens, and the contact lens 600 includes a ciliary muscle paralysis agent.

The light-blocking ring region 620 includes a photochromic material, and the photochromic material used in Example 6 is 1 ′ , 3′ -dihydro-1 ′ , 3 ′ , 3′ -trimethyl-6-nitrospiro[2H -1-benzopyran-2,2 ' -(2H)-indole]. The average transmittance of the light-blocking ring region 620 in visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 12.

<Example 7>

FIG. 9 is a schematic diagram illustrating a contact lens 700 according to Embodiment 7 of the present invention. In FIG. 9, the contact lens 700 includes an optical region 710 and a light-blocking ring region 720, the light-blocking ring region 720 is disposed around the center point O of the contact lens 700, and the inner peripheral edge 720A of the light-blocking ring region 720 is quadrangular. Specifically, the light-blocking ring region 720 includes three light-blocking portions, namely a first light-blocking portion 721, a second light-blocking portion 722, and a third light-blocking portion 723. The optical zone 710 is an area enclosed by a dotted line. In Embodiment 7, the optical zone 710 partially overlaps with the light-blocking ring zone 720.

The values of the CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 7 are recorded in Table XIII. For the definition of the aforementioned parameters, please refer to Example 1.

The material of the contact lens 700 is hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate, methacrylic acid, and N-vinyl-2-pyrrolidone. The contact lens 700 is a multifocal contact lens.

The light-blocking ring region 720 contains a photochromic material, and the photochromic material used in Example 7 is 1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3 ' -[ 3H] Naphtho[2,1-b][1,4]azine]. The average transmittance of the light-blocking ring region 720 in visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 14.

In addition, in Embodiment 7, the average transmittance of the first light blocking portion 721, the second light blocking portion 722, and the third light blocking portion 723 in visible light from inside to outside may be different. In Embodiment 7, the first The average transmittance of a light blocking portion 721 in visible light is Tavg1, the average transmittance of second light blocking portion 722 in visible light is Tavg2, and the average transmittance of third light blocking portion 723 in visible light is Tavg3, where Tavg1 >Tavg2 and Tavg3>Tavg2, Tavg1 may be equal to Tavg3 or unequal. In Table 14, the Tavg value is the minimum average transmittance among different light blocking parts (721-723), which means that the light blocking part (at least one of 721-723) has the best light blocking effect In other words, in Example 7, Tavg=Tavg2.

<Example 8>

FIG. 10 is a schematic diagram illustrating a contact lens 800 according to Embodiment 8 of the present invention. In FIG. 10, the contact lens 800 includes an optical region 810 and a light blocking ring region 820. The light blocking ring region 820 is disposed around the center point O of the contact lens 800, and the inner peripheral edge 820A of the light blocking ring region 820 is octagonal. Specifically, the light-blocking ring region 820 includes two light-blocking portions, namely a first light-blocking portion 821 and a second light-blocking portion 822 respectively. The optical zone 810 is an area enclosed by a dotted line. In Embodiment 8, the optical zone 810 partially overlaps with the light-blocking ring zone 820.

The values of the CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmaX-CDmin, CDmin/OD, BC and other parameters of Example 8 are recorded in Table 15. For the definition of the aforementioned parameters, please refer to Example 1.

The material of contact lens 800 is silicone glue, and the composition for preparing silicone glue contains the following monomers: hydroxyethyl methacrylate, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, 3-Ethyloxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane and methyl methacrylate. The contact lens 800 is a multifocal contact lens.

The light-blocking ring region 820 contains a photochromic material, and the photochromic material used in Example 8 is hydroxy-4-methyl-2H-naphtho(1,2-B)pyran-2-one. The average transmittance of the light-blocking ring region 820 in visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 16.

In addition, in Embodiment 8, the average transmittance of the first light blocking portion 821 and the second light blocking portion 822 in visible light may be different from the inside to the outside. In Embodiment 8, the first light blocking portion 821 is in visible light. The average transmissivity of is Tavg1, and the average transmissivity of the second light blocking portion 822 in visible light is Tavg2, where Tavg1<Tavg2. In Table 16, the value of Tavg is the minimum average transmittance among different light blocking parts (821-822), which means that the light blocking part (at least one of 821-822) has the best light blocking effect In other words, in Example 8, Tavg=Tavg1.

<Example 9>

FIG. 11 is a schematic diagram illustrating a contact lens 900 according to Embodiment 9 of the present invention. In FIG. 11, the contact lens 900 includes an optical region 910 and a light blocking ring region 920. The light blocking ring region 920 is disposed around the center point O of the contact lens 900, and the inner peripheral edge 920A of the light blocking ring region 920 is circular. The optical zone 910 is an area enclosed by a dotted line. In Embodiment 9, the optical zone 910 partially overlaps with the light-blocking ring zone 920.

The values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 9 are recorded in Table 17. For the definition of the aforementioned parameters, please refer to Example 1.

The material of the contact lens 900 is silicone glue, and the composition of the silicone glue contains the following monomers: hydroxyethyl methacrylate, methacryl oxypropyl tris(trimethylsiloxyalkyl) silane, (3 -Methacryloyloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methyl and methyl methacrylate. The contact lens 900 is a single focus contact lens.

The light-blocking ring region 920 contains a photochromic material, and the photochromic material used in Example 9 is (E)-benzylidene(diphenylmethylene)succinic anhydride. The average transmittance of the light-blocking ring region 920 to visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 18.

<Example 10>

FIG. 12 is a schematic diagram illustrating a contact lens 1000 according to Embodiment 10 of the present invention. In FIG. 12, the contact lens 1000 includes an optical region 1010 and a light blocking ring region 1020. The light blocking ring region 1020 is disposed around the center point O of the contact lens 1000, and the inner periphery 1020A of the light blocking ring region 1020 is circular. The optical zone 1010 is an area enclosed by a dotted line. In Example 10, the optical zone 1010 is offset from the light-blocking ring zone 1020.

The values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 10 are recorded in Table 19. For the definition of the aforementioned parameters, please refer to Example 1.

The material of contact lens 1000 is silicone glue. The composition of silicone glue contains the following monomers: hydroxyethyl methacrylate, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, Methacryloyloxypropyl tris(trimethylsiloxyalkyl) silane, 3-ethoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane and methyl methacrylate. The contact lens 1000 is a single focus contact lens, and the contact lens 1000 contains a ciliary muscle paralyzing agent.

The light-blocking ring region 1020 contains a photochromic material, and the photochromic material used in Example 10 is 9,10-dihydrophenanthrene. The average transmittance of the light-blocking ring region 1020 in visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 20.

<Example 11>

FIG. 13 is a schematic diagram illustrating a contact lens 1100 according to Embodiment 11 of the present invention. In FIG. 13, the contact lens 1100 includes an optical region 1110 and a light-blocking ring region 1120. The light-blocking ring region 1120 is disposed around the center point O of the contact lens 1100, and the inner periphery 1120A of the light-blocking ring region 1120 is circular. The optical zone 1110 is an area enclosed by a dotted line. In Embodiment 11, the optical zone 1110 is offset from the light-blocking ring zone 1120.

The values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 11 are recorded in Table 21. For the definition of the aforementioned parameters, please refer to Example 1. .

The material of the contact lens 1100 is silicone glue. The composition of the silicone glue contains the following monomers: hydroxyethyl methacrylate, N,N-dimethylacrylamide and (3-methacryloxy- 2-hydroxypropoxy)propylbis(trimethylsiloxy)methyl. The contact lens 1100 is a multifocal contact lens, and the contact lens 1100 includes a ciliary muscle paralysis agent.

The light-blocking ring region 1120 contains a photochromic material, and the photochromic material used in Example 11 contains 1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3 ' -[ 3H] Naphtho[2,1-b][1,4]azine] and (E)-benzylidene (diphenylmethylene) succinic anhydride. The average transmittance of the light-blocking ring region 1120 in visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 22.

<Example 12>

FIG. 14 is a schematic diagram illustrating a contact lens 1200 according to Embodiment 12 of the present invention. In FIG. 14, the contact lens 1200 includes an optical region 1210 and a light-blocking ring region 1220. The light-blocking ring region 1220 is disposed around the center point O of the contact lens 1200, and the inner periphery 1220A of the light-blocking ring region 1220 is circular. The optical area 1210 is an area enclosed by a dotted line. In Embodiment 12, the optical area 1210 partially overlaps with the light-blocking ring area 1220.

The values of CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, BC and other parameters of Example 12 are recorded in Table 23. For the definition of the aforementioned parameters, please refer to Example 1. .

The material of the contact lens 1200 is silicone glue, and the composition for preparing the silicone glue contains the following monomers: hydroxyethyl methacrylate, 2-methyl-2-acrylic acid-2,3-dihydroxypropyl ester, N-ethylene 2-pyrrolidone, N,N-dimethylacrylamide, methacryloxypropyl tris(trimethylsiloxyalkyl) silane, (3-methacryloxy-2-hydroxyl Propoxy)propyl bis(trimethylsiloxy)methyl, 3-ethoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane and methyl methacrylate. The contact lens 1200 is a multifocal contact lens.

The light-blocking ring region 1220 includes a photochromic material, and the photochromic material used in Example 12 includes 1 ′ , 3′ -dihydro-1 ′ , 3 ′ , 3′ -trimethyl-6-nitrospiro[2H -1-benzopyran-2,2 ' -(2H)-indole], hydroxy-4-methyl-2H-naphtho(1,2-B)pyran-2-one and 9,10- Dihydrophenanthrene. The average transmittance of the light-blocking ring region 1220 to visible light is Tavg, and the values before and after irradiated with light in the wavelength range of 200 nm to 400 nm for 10 seconds are shown in Table 24.

<Example 13>

FIG. 15 is a schematic diagram illustrating a contact lens 1300 according to Embodiment 13 of the present invention. In FIG. 15, the contact lens 1300 includes an optical region 1310 and a light blocking ring region 1320. The light blocking ring region 1320 is disposed around the center point O of the contact lens 1300, and the inner peripheral edge 1320A of the light blocking ring region 1320 is circular. The optical zone 1310 is an area enclosed by a dotted line. In Embodiment 13, the optical zone 1310 is offset from the light-blocking ring zone 1320. In Embodiment 13, the light-blocking ring-shaped region 1320 includes only one light-blocking portion (not otherwise labeled), and the light-blocking portion includes a plurality of micro-light-blocking portions 1320a. The micro-light-blocking portions 1320a are arranged in a radial manner, and this The average transmittance of the micro-blocking portions 1320a in visible light may be a gradual change, which means that different micro-blocking portions 1320a may have different color shade changes along the clockwise direction or the counterclockwise direction. In Example 13, In order to change from the position of 12 o'clock in the clockwise direction to light gradient, deep gradient, shallow gradient, and then deep gradient, in other embodiments, other color gradients may be arranged according to actual needs.

According to the contact lens of the present invention, the optical zone refers to the range covered by the base arc of the contact lens, that is, an area having refractive power.

According to the contact lens of the present invention, the parameter design is not limited to be used only on the front or back surface of the contact lens, and either one of the surfaces or the front and back surfaces can be designed at the same time.

According to the contact lens of the present invention, the light-blocking ring-shaped region can be formed on the contact lens by a process such as transfer, printing or coating, or the light-blocking material can be mixed into the light-blocking ring-shaped region In the composition, the light-blocking material is dispersed throughout the light-blocking ring area. In addition, by selecting and adjusting the concentration and color of the light-blocking material, a contact lens with a light-blocking effect can be made according to different needs. Different degrees of light transmittance are required to effectively reduce the average transmittance of visible light. Light blocking materials can use the Food and Drug Administration (TFDA) of the Department of Health of the Executive Yuan and the Food and Drug Administration of the United States. Administration, FDA) or any National Food and Drug Administration approved color materials that can be used for medical devices.

According to the contact lens of the present invention, the photo-variable material can be converted into a color with low visible light penetration by absorbing light (such as blue light, UV, etc.), effectively reducing or even blocking the penetration of visible light. When the light source disappears, the photo-induced change The material can be restored to the original visible light transmission rate, which is converted into a reversible reaction.

According to the contact lens of the present invention, the ciliary muscle paralysis agent includes but is not limited to atropine (Atropine; (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yltropate), topiramate ( Tropicamide; N-ethyl-3-hydroxy-2-phenyl-N-(4-pyridinylmethyl)propanamide), Cyclopentolate; 2-(dimethylamino)ethyl(1-hydroxycyclopentyl)(phenyl)acetate), rear Horse Tropine (Homatropine; (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-ylhydroxy(phenyl)acetate), Scopolamine; (1R, 2R, 4S, 5S ,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0 ^2,4 ]non-7-yl(2S)-3-hydroxy-2-phenylpropanoate) and eucatropine; 1, 2,2,6-tetramethyl-4-piperidinyl hydroxy(phenyl)acetate) and salts of the aforementioned substances. Ciliary muscle paralysis agent, also known as mydriatic agent, is a parasympathetic blocker, which is a non-selective M-type muscarinic receptor blocking agent, which can be blocked by blocking muscarinic The ciliary muscles that control the pupils are paralyzed and relaxed, and the pupils are enlarged.

Although the present invention has been disclosed as above in an embodiment, it is not intended to limit the present invention. Anyone who is familiar with this art can make various modifications and retouching without departing from the spirit and scope of the present invention, so the present invention is protected The scope shall be determined by the scope of the attached patent application.

10‧‧‧Contact lens

11‧‧‧Optical Zone

12‧‧‧Abnormity zone

12A‧‧‧Inner periphery

O‧‧‧Center

D‧‧‧Maximum diameter of contact lens

OD‧‧‧Maximum diameter of optical zone

CDmin‧‧‧Minimum diameter of light blocking ring area

CDmax‧‧‧Maximum diameter of light blocking ring area

Claims (33)

A contact lens, wherein the contact lens is a multifocal contact lens to reduce myopia, the contact lens includes: an optical zone; and at least a light-blocking ring zone, disposed around the center point of the contact lens; wherein the optical zone and the block At least one of the halo regions includes a photochromic material, the average transmittance of the light blocking ring region in visible light is Tavg, the minimum diameter of the light blocking ring region is CDmin, and the maximum diameter of the contact lens is D, which Meet the following conditions: 0%<Tavg<50%; and 0.01

CDmin/D

0.24. The contact lens as described in item 1 of the patent application scope, wherein the optical zone contains the photochromic material, the photochromic material is a spiropyran compound, a spiro 1,4-oxazane compound, naphtho A pyran-based compound, a spermic anhydride-based compound, a diarylethylene-based compound, or a combination thereof. The contact lens as described in item 2 of the patent application scope, wherein the light-blocking ring-shaped region contains the photochromic material, the photochromic material is a spiropyran compound, a spiro 1,4-oxonitrogen compound, Naphthopyran-based compounds, spermic anhydride-based compounds, diarylethylene-based compounds or combinations thereof. The contact lens according to item 1 of the patent application scope, wherein the maximum diameter of the light-blocking ring region is CDmax, and the maximum diameter of the contact lens is D, which satisfies the following conditions: 0.5

CDmax/D<1.0. The contact lens according to item 1 of the patent application scope, wherein the minimum diameter of the light-blocking ring region is CDmin, and the maximum diameter of the optical region is OD, which satisfies the following conditions: 0.05

CD min/OD<1.0. The contact lens as described in item 1 of the patent application scope, wherein the maximum diameter of the light-blocking ring region is CDmax, and the minimum diameter of the light-blocking ring region is CDmin, which satisfies the following conditions: CDmax-CDmin<9.0mm. The contact lens as recited in item 1 of the patent application range, wherein the light-blocking ring-shaped region includes at least two light-blocking portions, and the average transmittance of the light-blocking portions in visible light changes gradually. The contact lens as described in item 1 of the patent application scope, wherein the material of the contact lens is a silicone glue, and the composition for preparing the silicone glue contains at least three monomers, and the monomer is hydroxyethyl methacrylate , Methacrylic acid, 2-methyl-2-acrylic acid-2,3-dihydroxypropyl ester, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, methacryloxypropyl Tris(trimethylsiloxyalkyl) silane, (3-methacryloxy-2-hydroxypropoxy) Propyl bis(trimethylsiloxy)methyl, 3-ethoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane or methyl methacrylate. The contact lens as described in item 1 of the patent application scope, wherein the material of the contact lens is a hydrogel, and the composition for preparing the hydrogel includes at least three monomers, the monomers are hydroxyethyl methacrylate, methyl alcohol Acrylic acid, 2-methyl-2-acrylic acid-2,3-dihydroxypropyl ester, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide or methyl methacrylate. A contact lens product comprising: the contact lens as described in item 1 of the patent application scope; and an infiltration solution in which the contact lens is immersed in the infiltration solution; wherein at least one of the contact lens and the infiltration solution includes ciliary Muscle paralysis agent. A contact lens product, comprising: the contact lens as described in item 1 of the patent application scope; and an infiltration solution in which the contact lens is immersed in the infiltration solution; wherein at least one of the contact lens and the infiltration solution comprises mushroom poison Alkali receptor blocking drugs. A contact lens, comprising: an optical zone; and at least one light-blocking ring-shaped zone, arranged around the center point of the contact lens; wherein the minimum diameter of the light-blocking ring-shaped zone is CDmin, and the maximum diameter of the light-blocking ring-shaped zone is CDmax, The maximum diameter of the contact lens is D, which meets the following conditions: 0.01

CDmin/D

0.24; and 0.5

CDmax/D

0.89. The contact lens as described in item 12 of the patent application scope, wherein the contact lens is a multifocal contact lens that reduces myopia. The contact lens as described in item 13 of the patent application scope, wherein the minimum diameter of the light-blocking ring region is CDmin, and the maximum diameter of the optical region is OD, which satisfies the following conditions: 0.05

CDmin/OD<1.0. The contact lens according to item 14 of the patent application scope, wherein the maximum diameter of the light-blocking ring region is CDmax, and the minimum diameter of the light-blocking ring region is CDmin, which satisfies the following conditions: 1.5mm

CDmax-CDmin<8.0mm. The contact lens as described in item 14 of the patent application scope, wherein the average transmittance of the light-blocking ring region in visible light is Tavg, which satisfies the following conditions: 0%<Tavg

20%. The contact lens as described in item 14 of the patent application scope, wherein the base arc of the contact lens is BC, which satisfies the following conditions: 9.50mm

BC. The contact lens as recited in item 14 of the patent application range, wherein the contact lens is a double-layer contact lens, the contact lens includes an object-side layer and an image-side layer, and the object-side layer and the image-side layer have Color film, the color film contains a photochromic material. The contact lens as recited in item 14 of the patent application range, wherein the inner periphery of the light-blocking ring region is a polygon having at least eight sides. The contact lens as recited in item 14 of the patent application range, wherein the light-blocking ring-shaped region includes at least two light-blocking parts, there are gaps between different light-blocking parts, and the average transmittance of the light-blocking parts in visible light is gradually式变。 Style changes. The contact lens as described in Item 20 of the patent application range, wherein the average transmittance of the light blocking portions in visible light is shallow to deep from the inside to the outside. A contact lens product, comprising: the contact lens as described in item 12 of the patent application scope; and an infiltration solution in which the contact lens is immersed in the infiltration solution; wherein at least one of the contact lens and the infiltration solution includes ciliary Muscle paralysis agent, the weight percentage concentration of the ciliary muscle paralysis agent in the contact lens or in the infiltration solution is ConA, which satisfies the following conditions: 0.01%<ConA<0.5%. A contact lens, comprising: an optical zone; and at least one light-blocking ring zone, arranged around the center point of the contact lens; the minimum diameter of the light-blocking zone zone is CDmin, the maximum diameter of the contact lens is D, the optical zone The maximum diameter is OD, which meets the following conditions: 0.01

CDmin/D

0.24; and 0.05

CDmin/OD<1.0. The contact lens as described in item 23 of the patent application scope, wherein the contact lens is a multifocal contact lens that reduces myopia. The contact lens according to item 24 of the patent application scope, wherein the maximum diameter of the light-blocking ring region is CDmax, and the minimum diameter of the light-blocking ring region is CDmin, which satisfies the following conditions: 1.5mm

CDmax-CDmin<9.50mm. The contact lens according to item 25 of the patent application scope, wherein the maximum diameter of the light-blocking ring region is CDmax, and the maximum diameter of the contact lens is D, which satisfies the following conditions: 0.5

CDmax/D

0.97. The contact lens as described in item 25 of the patent application range, wherein the average transmittance of the light-blocking ring region in visible light is Tavg, which satisfies the following conditions: 0%<Tavg

35%. The contact lens as described in item 25 of the patent application scope, wherein the base arc of the contact lens is BC, which satisfies the following conditions: 9.50mm

BC. The contact lens as claimed in item 25 of the patent application scope, wherein the contact lens is a double-film layer contact lens, the contact lens comprises an object side layer and an image side layer, the object side layer and the image side layer have Color film, the color film contains a photochromic material. The contact lens as recited in item 25 of the patent application range, wherein the inner periphery of the light-blocking ring region is a polygon having at least eight sides. The contact lens as described in item 25 of the patent application range, wherein the light-blocking ring-shaped region includes at least two light-blocking parts, and there may be gaps between different light-blocking parts, and the average transmittance of the light-blocking parts in visible light gradually Layered change. The contact lens as described in item 31 of the patent application range, wherein the average transmittance of the light blocking portions in visible light is shallow to deep from the inside to the outside. A contact lens product comprising: the contact lens as described in item 23 of the patent application scope; and an infiltration solution in which the contact lens is immersed in the infiltration solution; wherein at least one of the contact lens and the infiltration solution includes ciliary Muscle paralysis agent, the weight percentage concentration of the ciliary muscle paralysis agent in the contact lens or in the infiltration solution is ConA, which satisfies the following conditions: 0.01%<ConA<0.5%.

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