TWI677327B - Spinal implant and method of manufacture thereof - Google Patents

Abstract

The invention discloses an intervertebral implant, which includes a front end, a rear end, and two side walls. The front end and the rear end are relative to an implantation direction of the intervertebral implant. The rear end has an injection hole. At least one of the two side walls has an oblique exit hole, and the opening direction of the oblique exit hole is opened on the side wall from the rear end toward the front end and inclined outward. The oblique exit hole communicates with the injection hole. The invention further discloses a method for manufacturing an intervertebral implant.

Description

Intervertebral implant and manufacturing method thereof

The invention relates to an intervertebral implant and a manufacturing method thereof.

The spine is one of the most important parts in determining human mobility. When a spinal disease occurs, it often has a considerable impact on patients, including causing pain, numbness, weakness, and even symptoms of incontinence or difficulty. Spondylopathy occurs mostly because the ligaments around the intervertebral disc are damaged or weakened, causing the nucleus pulposus to protrude from between the ligaments, or the vertebrae (or vertebral body) is collapsed or damaged due to aging and fractures. Both may cause nerves or spinal cords to be oppressed, causing patients to experience severe pain or impaired motor function of the lower limbs.

An intervertebral disc is a fibrocartilage disc that connects two adjacent vertebrae, and is located between the two vertebrae. It can be used as a buffer area between vertebrae, reducing the impact of external forces on the vertebrae and increasing the spinal motion. The intervertebral disc is composed of two parts, including the nucleus pulposus in the central part and anulus fibrosis in the peripheral part. The components of the nucleus pulposus are polysaccharides and water, which are used to cushion the stress and impact of the spine. A fibrous ring is a dense tissue composed of dozens of layers of annular and radial collagen fibers and elastic fibers, which can protect the nucleus pulposus and tightly connect adjacent vertebrae into one body.

If the disc degenerates, the nucleus pulposus will gradually lose its ability to absorb water and become dehydrated. At this time, the thickness of the nucleus pulposus will increase, and at the same time, fibrosis will occur, and the ability to absorb shocks will be lost. As a result, the pressure will directly act on the bone structure of the spine, resulting in vertebra wear and tear, spur formation, intervertebral ligament relaxation, and nerve Root pressure and other issues. In addition, degeneration of the intervertebral disc or abnormal stress on the spine can cause deformation of the fibrous ring and even rupture of the fibrous ring structure.

In addition to intervertebral disc degeneration that may develop into disc herniation, other possible causes include spondylolisthesis, spinal canal stenosis or other nerve compression symptoms. The current surgical method for treating severe degenerative discs is spinal fusion surgery, which is performed by the operator first using a device to destroy the outer fiber ring into the inner nucleus pulposus to clear the path for implantation. , Or remove the entire disc directly with Discectomy. The patient was then treated with Intervertebral Cage Fusion. The operator implants a spinal implant between the two adjacent vertebrae and fills them with bone grafting material to fuse the adjacent vertebrae together. The intervertebral implant is, for example, a spinal interbody fusion cage or an intervertebral cage. The main function of the implant is to restore the height between the vertebrae to a normal or suitable height. Bone graft materials include bone grafts. Bone grafts are, for example, autogenous bones, allogeneic bones, or artificial bone substitutes. They may be used with bone growth factors to promote the growth of bone grafts. Integration.

There are only two options for the conventional surgery to match the implantation of intervertebral implants and filling bone graft materials, but the effects are limited. The first method is to pre-fill the bone graft material in the implant space, and then implant the intervertebral implant. However, post-implantation intervertebral implants will compress the filled bone graft material, causing the bone graft material to squeeze to the two sides and the front end. In addition to the possible risks, it may also be difficult for the intervertebral implant to reach the intended location because the implant space has been filled with bone graft material.

The second method is to implant the intervertebral implant and then fill the bone graft material. However, the implantation space is limited after the intervertebral implant is implanted, so the bone graft material that can be filled is quite limited, affecting the effect and speed of fusion.

In order to solve the above problems, an intervertebral implant 9 appears on the market, as shown in FIG. 1, which is a schematic diagram of a conventional intervertebral implant. This type of intervertebral implant 9 has an injection hole 91 at one end and an injection space 92 inside, and the injection hole 91 and the injection space 92 communicate with each other. In addition, the intervertebral implant 9 has exit holes 93 on the upper and lower surfaces, and side exit holes 94 on the side wall. Both the exit hole 93 and the side exit hole 94 communicate with the injection space 92. The surgeon can first use the intervertebral implant holding device (Holder) to hold the intervertebral implant 9 and implant it into the affected area, and then use the bone graft material delivery component to remove the intervertebral implant 9 from the injection hole 91. The bone graft material is injected into the injection space 92. Then, the injected bone graft material can overflow from the exit hole 93 and the side exit hole 94 to contact the surrounding bone tissue, thereby accelerating the fusion between the vertebrae.

However, since the side exit hole 94 of the above design is a through hole perpendicular to the long axis direction of the intervertebral implant 9, the bone graft material overflowing in actual use is accumulated around the exit of the side exit hole 94, and the intervertebral Instead of filling the bone graft material around the front end of the implant 9, a sufficient amount of loosening and poor fusion results are caused in the implanted intervertebral implant 9. In addition, the bone graft material overflowing from the side exit hole 94 may be pushed backward and leak out from the opening of the implantation path, thereby damaging surrounding tissues.

Therefore, how to provide an intervertebral implant with a structural design that can guide the injected bone grafting material to an appropriate position to prevent the bone grafting material from accumulating in some areas or leaking backward from the implantation path has become an urgent desire in related fields Breakthrough points.

In view of the above-mentioned problems, the main object of the present invention is to provide an intervertebral implant and a method for manufacturing the same, by opening an oblique exit hole in the side wall, and the oblique exit is inclined from the rear end toward the front end and outward. It is opened on the side wall to solve the problem that the conventional intervertebral implant cannot disperse the bone grafting material, which leads to the accumulation around the outlet, the inability to transport to the front of the implant, or the backward leakage from the implant path.

To achieve the above object, the present invention provides an intervertebral implant including a front end, a rear end, and two side walls. The front end and the rear end are relative to an implantation direction of the intervertebral implant. The rear end has an injection hole. At least one of the two side walls has an oblique exit hole, the oblique exit hole is opened on the side wall from the rear end to the front end and obliquely outward, and the oblique exit hole is in communication with the injection hole.

According to an embodiment of the present invention, the intervertebral implant further includes an injection space, which is formed inside the intervertebral implant and communicates with the injection hole.

According to an embodiment of the present invention, the oblique exit hole communicates with the injection space through the injection hole.

According to an embodiment of the present invention, one side of the oblique exit hole near the front end is a guide wall.

According to an embodiment of the present invention, the guide wall and the implantation direction have a predetermined angle, and the predetermined angle is greater than 90 degrees.

According to an embodiment of the present invention, the intervertebral implant includes two oblique exit holes, two guide walls, and a shunt wall, and the shunt wall is located at the junction of the two guide walls.

According to an embodiment of the present invention, the intervertebral implant further includes a receiving space formed inside the intervertebral implant and close to the front end.

According to an embodiment of the present invention, at least one of the two side walls has a side exit hole, which is communicated with the accommodation space.

According to an embodiment of the present invention, the intervertebral implant further includes an upper surface and a lower surface. The upper surface has an upper exit hole, the lower surface has a lower exit hole, and the upper exit hole and the lower exit hole communicate with each other.

To achieve the above object, the present invention further provides an intervertebral implant including a front end, a rear end, and two side walls. The front end and the rear end are relative to an implantation direction of the intervertebral implant, and the rear end has an injection hole. At least one of the two sidewalls has an oblique exit hole. The oblique exit hole is opened on the side wall from the rear end to the front and obliquely outward, and the oblique exit hole communicates with the injection hole. One side of the oblique exit hole near the front end is a guide wall, and the guide wall and the implanted direction have a predetermined angle, and the predetermined angle is greater than 90 degrees.

According to an embodiment of the present invention, the intervertebral implant further includes an injection space and two oblique exit holes. The injection space is formed inside the intervertebral implant and communicates with the injection hole. Two oblique exit holes are located on two opposite sides of the injection space.

According to an embodiment of the present invention, the intervertebral implant further includes a receiving space and an upper surface. The accommodation space is formed inside the intervertebral implant and is close to the front end. The upper surface has an upper exit hole, and the hole diameter of the upper exit hole is greater than or equal to the hole diameter of the accommodation space.

To achieve the above object, the present invention further provides an intervertebral implant, which includes a front end, a rear end, two side walls, and a shunt wall. The front end and the rear end are relative to an implantation direction of the intervertebral implant. The rear end has an injection hole. The two side walls each have an oblique exit hole. The oblique exit hole is opened on the side wall from the rear end to the front and obliquely outward, and the oblique exit hole is in communication with the injection hole. One side of the oblique exit hole near the front end is a guide wall. The shunt wall is located at the junction of the guide walls of the two side walls.

According to an embodiment of the present invention, the guide wall and the implantation direction have a predetermined angle, and the predetermined angle is greater than 90 degrees.

According to an embodiment of the present invention, the intervertebral implant further includes a receiving space and an upper surface. The accommodation space is formed inside the intervertebral implant and is close to the front end. The upper surface has an upper exit hole, and the hole diameter of the upper exit hole is smaller than that of the accommodation space.

In order to achieve the above object, the present invention further provides a method for manufacturing an intervertebral implant, including the following steps: providing an intervertebral implant including a front end, a rear end, and two side walls; providing a jig and fixing Intervertebral implant; providing a tool having a predetermined angle between the tool and an implanted direction of the intervertebral implant, the predetermined angle is greater than 90 degrees; and the tool is processed on one of the two side walls to An oblique exit hole is formed extending from the rear end to the front end and obliquely outward.

According to an embodiment of the present invention, one side of the oblique exit hole near the front end is a guide wall, and the guide wall and the implanted direction have a predetermined angle.

According to an embodiment of the present invention, the grinding knife performs grinding on one of the two side walls with an ellipse-like rotation track.

According to an embodiment of the present invention, the grinding knife is cylindrical or water droplet-shaped.

According to the above description, according to the intervertebral implant of the present invention and the manufacturing method thereof, the rear end has an injection hole, and at least one side wall has an oblique exit hole. The oblique exit hole is opened on the side wall from the rear end to the front and obliquely outward, and the oblique exit hole is in communication with the injection hole. The bone graft material can be injected from the injection hole at the rear end, and is guided to move outward and forward of the intervertebral implant through the configuration of the oblique exit hole, so that the bone graft material is dispersed and filled in the implantation space. Better to avoid excessive accumulation in some areas.

In order to make your reviewing committee better understand the technical content of the present invention, specific preferred embodiments are described below.

FIG. 2 is a schematic view of a first embodiment of the intervertebral implant of the present invention, FIG. 3A is a partial cross-sectional schematic view of the intervertebral implant shown in FIG. 2, and FIG. 3B is an intervertebral implant shown in FIG. 3A For a partial cross-sectional view from another perspective, please refer to FIG. 2 and FIG. 3A simultaneously. First, the intervertebral implant 1 of this embodiment is described using an intervertebral cage (or a cage) as an example. The intervertebral implant 1 includes a front end 11, a rear end 12, and two side walls 13. The front end 11 and the rear end 12 are an implantation direction P relative to the intervertebral implant 1, and the implantation direction P is the moving direction of the intervertebral implant 1 when it is implanted in the affected part (see the figure first). 6A). When the intervertebral implant 1 is implanted in the affected part (for example, the damaged or degenerated intervertebral disc 80 between the two vertebrae, or the position of the originally damaged or degenerated intervertebral disc 80 is removed, refer to FIG. 6A). The end close to the affected part is called the front end 11 in this embodiment; otherwise, it is called the back end 12. In other words, the front end 11 and the rear end 12 are respectively located at opposite ends of the intervertebral implant 1, and the line connecting the front end 11 and the rear end 12 is parallel to the implantation direction P of the intervertebral implant 1. In this embodiment, the implantation direction P and the long axis of the intervertebral implant 1 are parallel to each other.

Generally, the surgeon can use the intervertebral implant holding device (Holder) to connect the rear end 12 of the intervertebral implant 1, thereby fixing and holding the intervertebral implant 1. The rear end 12 of this embodiment has an injection hole 121, and the inside of the injection hole 121 has an internal thread, which cooperates with the external thread at the front end of the holding device, and connects the holding device and the intervertebral implant by means of a screw lock. 1 is fixed together for the operator to operate the holding device to implant the intervertebral implant 1 into the affected part. In this embodiment, the intervertebral implant 1 further includes an injection space 14 which is formed inside the intervertebral implant 1 and communicates with the injection hole 121. The holding device not only plays the role of moving the intervertebral implant 1, but also can be combined with a feeding component for transporting the bone graft material for the operator to fill the bone graft material into the injection space 14 from the injection hole 121 and then disperse it to the implant. In space. Of course, in other embodiments of the present invention, the intervertebral implant 1 may be directly combined with a feeding component for transporting bone graft material by using the injection hole 121, and the present invention is not limited thereto. The implanted bone graft material may be, for example, but not limited to, autogenous bone, allogeneic bone, or bone graft substitutes.

Please refer to FIG. 2 and FIG. 3B at the same time. The two side walls 13 each have an oblique exit hole 131, and the two oblique exit holes 131 are respectively located on two opposite sides of the injection space 14. The oblique exit hole 131 is formed in the side wall 13 from the rear end 12 to the front end 11 and obliquely outward. In detail, the oblique exit hole 131 is an opening provided in the side wall 13 and penetrating through the side wall 13, so there are openings on the inner side of the side wall 13 (that is, the inside of the intervertebral implant 1) and the outer side. Among them, the opening of the oblique exit hole 131 on the inner side of the side wall 13 is closer to the rear end 12, and the opening of the oblique exit hole 131 on the outer side of the side wall 13 is closer to the front end 11 to form an oblique outward from the rear end 12 to the front end 11 and outward. An opening (inclined exit hole 131) extending in the direction. The oblique exit hole 131 communicates with the injection space 14 located inside the intervertebral implant 1, and further communicates with the injection hole 121. The bone grafting material can be filled into the injection space 14 from the injection hole 121. When the amount of injection increases, part of the bone grafting material will be pushed to move around the injection space 14 and then enter the opening connecting the injection space 14 and the outside, including斜 出 孔 131.

The movement direction of the bone graft material entering the oblique exit hole 131 is limited and can only be pushed outward along the oblique exit hole 131. For example, the bone graft material is guided to the outside of the side wall 13 by the direction in which the oblique exit hole 131 itself is opened. Therefore, the oblique exit hole 131 extends toward the front end 11 and obliquely outwards, so that the bone graft material can be guided to output in the direction of the front end 11 preferentially, and then the bone implantation can be filled from the implantation space near the front end 11 Material, and then slowly pile up. Comparatively speaking, the conventional intervertebral implant 9 only has a vertical through-hole side exit hole 94 on the side wall. After the bone graft material is pushed out along the side exit hole 94, it is easy to stay near the exit. After the bone grafting material of the side exit hole 94 is continuously squeezed, it will become compact and difficult to move, resulting in insufficient bone grafting material filled in the implantation space at the front end of the intervertebral implant 9 and being excessively concentrated in part. Area (outside of the side exit hole 94).

FIG. 4 is a top view of the intervertebral implant shown in FIG. 3A. Please refer to FIG. 3A, FIG. 3B and FIG. 4 at the same time. Since the oblique exit hole 131 is an opening extending toward the front end 11 and obliquely outward, one side of the oblique exit hole 131 near the front end 11 is a guide wall 132, and the guide wall 132 is an arc-shaped side wall. Helps strengthen the flow of bone graft material along the oblique exit hole 131. Specifically, there is a predetermined angle q1 between the guide wall 132 and the implantation direction P, and the predetermined angle q1 is greater than 90 degrees. The oblique exit hole 131 in this embodiment may be a circular or oval channel, preferably an oval channel, as shown in FIG. 2 to increase the space for guiding the bone graft material and maintain the bone graft material. Fluidity and avoiding excessive processing difficulties.

In this embodiment, the oblique exit hole 131 and the guide wall 132 thereof can be manufactured by using a tool, for example, by using a tool grinding method. FIG. 5A is a flowchart of the steps of the method for manufacturing the intervertebral implant shown in FIG. 2, FIG. 5B is a schematic diagram of step S30 shown in FIG. 5A, and FIG. 5C is a schematic diagram of step S40 shown in FIG. 5A. 5A, 5B and 5C. The manufacturing method of the intervertebral implant 1 of this embodiment includes the following steps: providing an intervertebral implant 1a, the intervertebral implant 1a includes a front end 11a, a rear end 12a, and two side walls 13a (step S10) ); Provide a jig to fix the intervertebral implant 1a (step S20); provide a tool 2, the tool 2 and a implanted direction P of the intervertebral implant 1a have a predetermined angle q2, a predetermined angle q2 is greater than 90 degrees (step S30); and the tool 2 is processed on one of the two side walls 13a to form an inclined exit hole 131a extending from the rear end 12a to the front end 11a and outwardly obliquely (step S40).

In step S20, a jig is first provided to fix the intervertebral implant 1a. It should be noted that the intervertebral implant 1a at this time is a semi-finished product, which has a front end 11a, a rear end 12a, and two side walls 13a. Moreover, the interior of the intervertebral implant 1a can be processed in advance to form an injection space 14a, but the side wall 13a is still closed and the oblique exit hole 131a has not been opened yet. Preferably, the intervertebral implant 1a may be made of a polymer material that is biocompatible or sterilizable at high temperature and high humidity, such as polyetheretherketone (PEEK). The intervertebral implant 1a is first processed to form a penetrating upper exit hole 151 and a lower exit hole 161 (refer to FIG. 2), and then a cylindrical jig is used to penetrate the upper exit hole 151 and the intervertebral implant 1a horizontally from the horizontal direction. The exit hole 161 is lowered to fix the intervertebral implant 1 a with the side wall 13 a of the intervertebral implant 1 a facing upward, and is intended to be processed by the tool 2.

After the semi-finished intervertebral implant 1a is fixed with a jig, the cutter 2 is tilted relative to one of the two side walls 13a (step S30). As shown in FIG. 5B and FIG. 5C, there is a predetermined angle q2 between the tool 2 and the implantation direction P of the intervertebral implant 1a, and the predetermined angle q2 is greater than 90 degrees, preferably between 110 degrees and 130 degrees. In between, the predetermined angle q2 of this embodiment is 120 degrees. It should be noted that the predetermined angle q2 described in this embodiment refers to an included angle between the tool 2 and the side wall 13a, and is an included angle between the side wall 13a and the tool 2 near the rear end 12a.

Next, the tool 2 starts grinding on one of the side walls 13a (step S40). The tool 2 moves from the outer surface of the side wall 13a to the inside of the intervertebral implant 1a, as shown in FIGS. 5B and 5C. There is also a predetermined angle q2 between the direction M and the implanted direction P. With the design of the predetermined angle q2, an oblique exit hole 131a extending from the rear end 12a to the front end 11a and outwardly obliquely is formed, and the oblique exit hole 131a communicates with the injection space 14a. In addition, one side of the oblique exit hole 131a near the front end 11a is a guide wall 132a, and the predetermined angle q1 (refer to FIG. 4) between the guide wall 132a and the implantation direction P is the same as that of the tool The predetermined angle q2 between 2 and the side wall 13a is the same. The predetermined angle q1 and the predetermined angle q2 in this embodiment are both 120 degrees. In this embodiment, the cutter 2 may also be cylindrical or drop-shaped, and is polished on the side wall 13a with an ellipse-like rotation track, and an ellipse-like oblique exit hole 131a may also be formed.

Then, steps S30 and S40 are repeated on the other side wall 13a to form the intervertebral implant 1 as shown in FIG. 4. It should also be noted that the present invention does not limit the number of the inclined exit holes 131, and there may be only one inclined exit hole 131, that is, one of the at least two side walls 13 has an inclined exit hole 131. In addition, there may be more than one inclined exit hole 131 in the same sidewall 13.

Please refer to FIG. 2, FIG. 3A and FIG. 3B together. The intervertebral implant 1 also includes an upper surface 15 and a lower surface 16. The upper surface 15 has an upper exit hole 151 and the lower surface 16 has an lower exit hole 161. . The upper exit hole 151 and the lower exit hole 161 communicate with the injection space 14 respectively, so that the upper exit hole 151 and the lower exit hole 161 can communicate with each other through the injection space 14. In other words, the rear side of the injection space 14 communicates with the injection hole 121, the left and right sides communicate with the oblique exit hole 131, and the upper and lower sides communicate with the upper exit hole 151 and the lower exit hole 161, respectively.

Preferably, the intervertebral implant 1 further includes a receiving space 17 formed inside the intervertebral implant 1 and closer to the front end 11 than the injection space 14. In this embodiment, the accommodating space 17 is a through hole close to the front end 11, so holes 171 are respectively formed on the upper surface 15 and the lower surface 16. In addition, at least one of the two side walls 13 has a side exit hole 172, which is in communication with the accommodation space 17. As shown in FIG. 4, the side exit hole 172 is perpendicular to the implantation direction P, in other words, the angle between the side exit hole 172 and the implantation direction P is substantially 90 degrees. The accommodating space 17 is used for accommodating bone graft material, and may be, for example, but not limited to, autogenous bone, allogeneic bone, or artificial bone substitute, but is preferably autologous bone. Before the intervertebral implant 1 is implanted in the affected part, the bone graft material can be placed in the accommodation space 17 and part of the bone graft material can be exposed from the exit hole 171 and the side exit hole 172 outside the intervertebral implant 1 .

Please refer to FIG. 6A and FIG. 6B. FIG. 6A is a side view of the intervertebral implant implanted into the intervertebral disc shown in FIG. 2, and FIG. 6B is a top view of the intervertebral implant implanted into the intervertebral disc shown in FIG. 6A. After the intervertebral implant 1 is implanted into the intervertebral disc 80 of the patient, the autogenous bone previously placed in the accommodating space 17 will be exposed from the exit hole 171 and contact the adjacent two vertebrae 81 and 82. Next, the artificial bone substitute is injected from the injection hole 121 of the rear end 12 and fills the injection space 14. After the artificial bone substitute is pushed into the oblique exit hole 131, it can be guided along the anterior guide wall 132 toward the outside of the intervertebral implant 1 and the front end 11 as shown in FIG. 6B, so that The artificial bone substitute can be preferentially filled in the implant space near the front end 11, which is beneficial to completely fill the space other than the intervertebral implant 1, especially the space on both sides of the intervertebral implant 1, to help induce the upper and lower vertebrae 81, 82 Fusion growth on both sides of the intervertebral implant 1. The artificial bone substitute can overflow from the upper exit hole 151 or the lower exit hole 161 to contact the upper and lower vertebrae 81 and 82. It can also provide the effect of inducing the fusion of the upper and lower vertebrae 81 and 82 to form the upper vertebrae 81 through the upper exit hole. 151. The fused bone structure of the accommodation space 17 and the lower exit hole 161 to the lower vertebra 82.

In the first embodiment, the ratio of the injection space 14 and the accommodation space 17 is substantially the same, or the injection space 14 is slightly larger than the accommodation space 17. In other words, the aperture R1 of the upper exit hole 151 is greater than or equal to the aperture R2 of the accommodation space 17, as shown in FIG. 4. This type of intervertebral implant 1 can be applied to the affected part where the required or available amount of autologous bone is less. Preferably, the diameter R3 of the oblique exit hole 131 in this embodiment may be larger than 1/4 of the total length L of the intervertebral implant 1. Because the distance between the injection hole 121 and the guide wall 132 is long, and the diameter R3 of the oblique exit hole 131 is relatively large, the injected bone meal can be smoothly guided into the channel of the oblique exit hole 131, which can overflow the intervertebral implant. The outside of the inlet 1 is prevented from accumulating in the injection space 14.

In other embodiments, the accommodating space 17b may be larger than the injection space 14b. The intervertebral implant 1b of the second embodiment is further described below. FIG. 7 is a schematic view of a second embodiment of the intervertebral implant of the present invention, FIG. 8A is a partial cross-sectional schematic view of the intervertebral implant shown in FIG. 2, and FIG. 8B is an intervertebral implant shown in FIG. 8A For a partial cross-sectional view from another perspective, please refer to FIG. 7 and FIG. 8A simultaneously. The intervertebral implant 1b in this embodiment also includes a front end 11b, a rear end 12b, and two side walls 13b. The rear end 12b has an injection hole 121b, and the two side walls 13b each have an oblique exit hole 131b. The oblique exit hole 131b is also opened on the side wall 13b in the direction of the rear end 12b oblique outward and toward the front end 11b, and the side of the oblique exit hole 131b near the front end 11b is a guide wall 132b. The upper surface 15b of the intervertebral implant 1b has an upper exit hole 151b, and the lower surface 16b has a lower exit hole 161b. The injection hole 121b, the oblique exit hole 131b, the upper exit hole 151b, and the lower exit hole 161b are all in communication with the injection space 14b inside the intervertebral implant 1b.

FIG. 9 is a top view of the intervertebral implant shown in FIG. 8A. Please refer to FIG. 9 for reference. The intervertebral implant 1b of this embodiment also has a receiving space 17b and is close to the front end 11b. One of the differences from the intervertebral implant 1 of the first embodiment is the proportional relationship between the accommodation space 17b and the injection space 14b. In this embodiment, the injection space 14b is smaller than the accommodating space 17b, so that the aperture R1 of the upper exit hole 151b is also smaller than the aperture R2 of the accommodating space 17b. The accommodating space 17b is used for accommodating the autogenous bone, so the intervertebral implant 1b of this embodiment can be applied to the affected part where autogenous bone is used in a large amount.

Compared to the intervertebral implant 1 of the first embodiment, in this embodiment, the intervertebral implant 1b further includes a shunt wall 18b, and the shunt wall 18b is located between the two guide walls 132b. That is, the dividing wall 18b is located at the boundary of the guide wall 132b of the two side walls 13b. The artificial bone substitute injected from the injection hole 121b will be gradually pushed forward in the injection space 14b. When it comes into contact with the split wall 18b, the configuration of the split wall 18b similar to a pyramid or a truncated cone will help the artificial bone. The substitutes are dispersed to both sides and enter the oblique exit holes 131b respectively along the guide wall 132b, so that the guide wall 132b restricts the flow direction and moves along the guide wall 132b to the outer side of the intervertebral implant 1b and the front end 11b. . The design of the intervertebral implant 1b of this embodiment prevents the bone graft material injected into the injection space 14b from being stacked at the junction of the two oblique exit holes 131b because it is pushed forward, that is, it does not It will be pushed to accumulate at the front position in the straight direction of the injection hole 121b, which will help the bone graft material injected into the intervertebral implant 1b to fill the implantation space.

To sum up, according to the intervertebral implant of the present invention and the manufacturing method thereof, the rear end has an injection hole, and at least one side wall has an oblique exit hole. The oblique exit hole is opened on the side wall from the rear end to the front and obliquely outward, and the oblique exit hole is in communication with the injection hole. The bone graft material can be injected from the injection hole at the rear end, and is guided to move outward and forward of the intervertebral implant through the configuration of the oblique exit hole, so that the bone graft material is dispersed and filled in the implantation space. Better to avoid excessive accumulation in some areas.

It should be noted that the above-mentioned many embodiments are examples for convenience of explanation, and the scope of the claimed rights of the present invention shall be based on the scope of the patent application, rather than being limited to the above-mentioned embodiments.

1, 1a, 1b, 9‧‧‧ intervertebral implants

11, 11a, 11b ‧‧‧ Front

12, 12a, 12b ‧‧‧ back end

121, 121b, 91‧‧‧ injection holes

13, 13a, 13b‧‧‧ sidewall

131, 131a, 131b‧‧‧ oblique exit hole

132, 132a, 132b‧‧‧Guide wall

14, 14a, 14b, 92‧‧‧ into space

15, 15b‧‧‧ Top surface

151, 151b‧‧‧

16, 16b‧‧‧ lower surface

161, 161b

17, 17b‧‧‧ accommodation space

171, 172b, 93‧‧‧ outlets

172, 172b, 94‧‧‧ side exit

18b‧‧‧ split wall

2‧‧‧ cutter

80‧‧‧Intervertebral Disc

81, 82‧‧‧ vertebra

L‧‧‧ length

M‧‧‧ direction of movement

P‧‧‧ implantation direction

R1, R2, R3 ‧‧‧ Aperture

S20 ～ S40‧‧‧‧Steps

q1, q2‧‧‧ predetermined angle

FIG. 1 is a schematic view of a conventional intervertebral implant. FIG. 2 is a schematic diagram of a first embodiment of the intervertebral implant of the present invention. 3A is a schematic partial cross-sectional view of the intervertebral implant shown in FIG. 2. 3B is a schematic partial cross-sectional view of the intervertebral implant shown in FIG. 3A from another perspective. FIG. 4 is a top view of the intervertebral implant shown in FIG. 3A. FIG. 5A is a flowchart of steps in a method of manufacturing the intervertebral implant shown in FIG. 2. FIG. 5B is a schematic diagram of step S30 shown in FIG. 5A. FIG. 5C is a schematic diagram of step S40 shown in FIG. 5A. FIG. 6A is a side view of the intervertebral implant implanted into the intervertebral disc shown in FIG. 2. FIG. 6B is a top view of the intervertebral implant implanted into the intervertebral disc shown in FIG. 6A. FIG. 7 is a schematic diagram of a second embodiment of the intervertebral implant of the present invention. FIG. 8A is a schematic partial cross-sectional view of the intervertebral implant shown in FIG. 2. 8B is a schematic partial cross-sectional view of the intervertebral implant shown in FIG. 8A from another perspective. FIG. 9 is a top view of the intervertebral implant shown in FIG. 8A.

Claims (19)

An intervertebral implant includes: a front end; a rear end, the front end and the rear end being an implanted direction relative to the intervertebral implant, the rear end having an injection hole; and two side walls, At least one of the two side walls has an oblique exit hole, the oblique exit hole is opened on the side wall from the rear end toward the front end and inclined outward, and the oblique exit hole is in communication with the injection hole. The intervertebral implant according to item 1 of the patent application scope further includes: an injection space formed in the interior of the intervertebral implant and communicating with the injection hole. The intervertebral implant according to item 2 of the scope of patent application, wherein the oblique exit hole communicates with the injection hole by communicating with the injection space. The intervertebral implant according to item 1 of the patent application scope, wherein one side of the oblique exit hole near the front end is a guide wall. The intervertebral implant according to item 4 of the scope of patent application, wherein the guide wall and the implanted direction have a predetermined angle, and the predetermined angle is greater than 90 degrees. The intervertebral implant according to item 4 of the scope of patent application, wherein the intervertebral implant includes two oblique exit holes, two guide walls, and a shunt wall, and the shunt wall is located at the junction of the two guide walls. Office. The intervertebral implant according to item 1 of the patent application scope further includes: an accommodation space formed inside the intervertebral implant and close to the front end. The intervertebral implant according to item 7 of the scope of patent application, wherein at least one of the two side walls has a side exit hole, which is in communication with the accommodation space. The intervertebral implant according to item 1 of the scope of patent application, further comprising: an upper surface having an upper exit hole; and a lower surface having a lower exit hole, and the upper exit hole and the lower exit hole are mutually Connected. An intervertebral implant includes: a front end; a rear end, the front end and the rear end being an implanted direction relative to the intervertebral implant, the rear end having an injection hole; and two side walls, At least one of the two side walls has an oblique exit hole, the oblique exit hole is opened on the side wall from the rear end to the front end and obliquely outward, and communicates with the injection hole, and the oblique exit hole A side near the front end is a guide wall, and the guide wall and the implanted direction have a predetermined angle, and the predetermined angle is greater than 90 degrees. The intervertebral implant according to item 10 of the scope of patent application, further comprising: an injection space formed inside the intervertebral implant and communicating with the injection hole; and two the oblique exit hole, two The oblique exit holes are located on opposite sides of the injection space. The intervertebral implant according to item 10 of the patent application scope further includes: an accommodation space formed inside the intervertebral implant and close to the front end; and an upper surface having an upper exit The hole has a diameter larger than or equal to the diameter of the accommodating space. An intervertebral implant includes: a front end; a rear end, the front end and the rear end being an implanted direction relative to the intervertebral implant, the rear end having an injection hole; two side walls, respectively The oblique exit hole is opened on the side wall from the rear end to the front end and obliquely outwards, and communicates with the injection hole, and the oblique exit hole is close to one side of the front end. A guide wall; and a diverting wall at the junction of the guide walls of the two side walls. The intervertebral implant according to item 13 of the patent application, wherein the guide wall and the implantation direction have a predetermined angle, and the predetermined angle is greater than 90 degrees. The intervertebral implant according to item 13 of the scope of patent application, further comprising: an accommodation space formed inside the intervertebral implant and close to the front end; and an upper surface having an upper exit The hole has a diameter smaller than that of the accommodating space. A method for manufacturing an intervertebral implant includes the following steps: providing an intervertebral implant including a front end, a rear end, and two side walls; providing a jig to fix the intervertebral implant Providing a tool having a predetermined angle between the tool and an implanted direction of the intervertebral implant, the predetermined angle being greater than 90 degrees; and processing the tool on one of the two side walls to The oblique exit hole extending from the rear end toward the front end and obliquely outward is formed. The method for manufacturing an intervertebral implant according to item 16 of the application, wherein a side of the oblique exit hole near the front end is a guide wall, and the guide wall and the implantation direction have a The predetermined angle. According to the method for manufacturing an intervertebral implant according to item 16 of the scope of the patent application, wherein the grinding knife grinds one of the two side walls with an ellipse-like rotation track. The method for manufacturing an intervertebral implant according to item 16 of the patent application, wherein the grinding knife is cylindrical or water drop-shaped.