TWI654431B - 樣品分析物濃度之漸進式近似 - Google Patents
樣品分析物濃度之漸進式近似Info
- Publication number
- TWI654431B TWI654431B TW107101865A TW107101865A TWI654431B TW I654431 B TWI654431 B TW I654431B TW 107101865 A TW107101865 A TW 107101865A TW 107101865 A TW107101865 A TW 107101865A TW I654431 B TWI654431 B TW I654431B
- Authority
- TW
- Taiwan
- Prior art keywords
- concentration
- analyte
- virtual reference
- sample
- output signal
- Prior art date
Links
- 239000012491 analyte Substances 0.000 title claims abstract description 334
- 230000000750 progressive effect Effects 0.000 title abstract description 43
- 238000004873 anchoring Methods 0.000 claims abstract description 128
- 238000004458 analytical method Methods 0.000 claims abstract description 121
- 230000004044 response Effects 0.000 claims description 65
- 238000012935 Averaging Methods 0.000 claims description 18
- 239000000523 sample Substances 0.000 abstract description 222
- 238000005259 measurement Methods 0.000 abstract description 67
- 239000013074 reference sample Substances 0.000 abstract description 31
- 230000009897 systematic effect Effects 0.000 abstract description 29
- 238000012360 testing method Methods 0.000 abstract description 22
- 230000006872 improvement Effects 0.000 abstract description 11
- 238000000034 method Methods 0.000 description 84
- 238000001514 detection method Methods 0.000 description 46
- 210000004369 blood Anatomy 0.000 description 35
- 239000008280 blood Substances 0.000 description 35
- 238000012937 correction Methods 0.000 description 34
- 230000003287 optical effect Effects 0.000 description 34
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 20
- 239000008103 glucose Substances 0.000 description 20
- 230000007717 exclusion Effects 0.000 description 17
- 239000013060 biological fluid Substances 0.000 description 16
- 239000003153 chemical reaction reagent Substances 0.000 description 13
- 239000004020 conductor Substances 0.000 description 13
- 238000006243 chemical reaction Methods 0.000 description 12
- 238000010606 normalization Methods 0.000 description 12
- 239000000126 substance Substances 0.000 description 12
- 230000000694 effects Effects 0.000 description 10
- 238000012417 linear regression Methods 0.000 description 10
- 230000008569 process Effects 0.000 description 10
- 238000006479 redox reaction Methods 0.000 description 10
- 238000004891 communication Methods 0.000 description 9
- 102000001554 Hemoglobins Human genes 0.000 description 8
- 108010054147 Hemoglobins Proteins 0.000 description 8
- 238000005534 hematocrit Methods 0.000 description 8
- 102000004190 Enzymes Human genes 0.000 description 7
- 108090000790 Enzymes Proteins 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 7
- 238000012545 processing Methods 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 230000009467 reduction Effects 0.000 description 6
- 238000006722 reduction reaction Methods 0.000 description 6
- 239000007795 chemical reaction product Substances 0.000 description 5
- 150000003278 haem Chemical class 0.000 description 5
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 4
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 3
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- 238000011088 calibration curve Methods 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 206010012601 diabetes mellitus Diseases 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000002452 interceptive effect Effects 0.000 description 3
- 238000011002 quantification Methods 0.000 description 3
- 238000007619 statistical method Methods 0.000 description 3
- 229940116269 uric acid Drugs 0.000 description 3
- 238000004832 voltammetry Methods 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 102000017011 Glycated Hemoglobin A Human genes 0.000 description 2
- 230000002238 attenuated effect Effects 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000000840 electrochemical analysis Methods 0.000 description 2
- 238000002848 electrochemical method Methods 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 108091005995 glycated hemoglobin Proteins 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 229960005489 paracetamol Drugs 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000001568 sexual effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 125000003831 tetrazolyl group Chemical group 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000004082 amperometric method Methods 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- VZWXIQHBIQLMPN-UHFFFAOYSA-N chromane Chemical compound C1=CC=C2CCCOC2=C1 VZWXIQHBIQLMPN-UHFFFAOYSA-N 0.000 description 1
- 229920001940 conductive polymer Polymers 0.000 description 1
- 238000003869 coulometry Methods 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000005206 flow analysis Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000021588 free fatty acids Nutrition 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000002977 intracellular fluid Anatomy 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- TYQCGQRIZGCHNB-JLAZNSOCSA-N l-ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(O)=C(O)C1=O TYQCGQRIZGCHNB-JLAZNSOCSA-N 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000011325 microbead Substances 0.000 description 1
- VMGAPWLDMVPYIA-HIDZBRGKSA-N n'-amino-n-iminomethanimidamide Chemical compound N\N=C\N=N VMGAPWLDMVPYIA-HIDZBRGKSA-N 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000004313 potentiometry Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000002277 temperature effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Artificial Intelligence (AREA)
- Software Systems (AREA)
- Epidemiology (AREA)
- Evolutionary Biology (AREA)
- Databases & Information Systems (AREA)
- Theoretical Computer Science (AREA)
- Data Mining & Analysis (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Evolutionary Computation (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Bioethics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Signal Processing (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361781771P | 2013-03-14 | 2013-03-14 | |
| US61/781,771 | 2013-03-14 | ||
| PCT/US2014/023167 WO2014159354A1 (en) | 2013-03-14 | 2014-03-11 | Progressive approximation of sample analyte concentration |
| ??PCT/US14/23167 | 2014-03-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201818072A TW201818072A (zh) | 2018-05-16 |
| TWI654431B true TWI654431B (zh) | 2019-03-21 |
Family
ID=50942766
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW107101865A TWI654431B (zh) | 2013-03-14 | 2014-03-13 | 樣品分析物濃度之漸進式近似 |
| TW103108989A TWI621852B (zh) | 2013-03-14 | 2014-03-13 | 樣品分析物濃度之漸進式近似 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW103108989A TWI621852B (zh) | 2013-03-14 | 2014-03-13 | 樣品分析物濃度之漸進式近似 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9933441B2 (OSRAM) |
| EP (2) | EP3457141B1 (OSRAM) |
| JP (2) | JP6446023B2 (OSRAM) |
| CN (1) | CN105308461B (OSRAM) |
| CA (1) | CA2902545A1 (OSRAM) |
| ES (1) | ES2715407T3 (OSRAM) |
| IL (1) | IL240817B (OSRAM) |
| TW (2) | TWI654431B (OSRAM) |
| WO (1) | WO2014159354A1 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX368104B (es) * | 2010-03-22 | 2019-09-19 | Ascensia Diabetes Care Holdings Ag | Compensacion residual para un biosensor. |
| FI128124B (en) * | 2016-04-25 | 2019-10-15 | Teknologian Tutkimuskeskus Vtt Oy | Optical sensor, systems and procedures |
| CN109073646A (zh) * | 2016-05-13 | 2018-12-21 | 荣研化学株式会社 | 求取待测物在对比物中所占比例的方法、程序、存储介质及装置 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201120444A (en) | 2009-12-14 | 2011-06-16 | Taidoc Technology Corp | Electrochemical biosensing test strip, biosensing meter, system and measuring method for analyte measurement incorporating a hematocrit correction |
| CN102116752A (zh) | 2009-12-30 | 2011-07-06 | 生命扫描有限公司 | 使用填充时间改进生物传感器的精确度的系统、装置和方法 |
| US20110231105A1 (en) | 2010-03-22 | 2011-09-22 | Bayer Healthcare Llc | Residual Compensation Including Underfill Error |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6153069A (en) | 1995-02-09 | 2000-11-28 | Tall Oak Ventures | Apparatus for amperometric Diagnostic analysis |
| US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
| AU6157898A (en) | 1997-02-06 | 1998-08-26 | E. Heller & Company | Small volume (in vitro) analyte sensor |
| US6749739B2 (en) * | 2002-10-07 | 2004-06-15 | Eci Technology, Inc. | Detection of suppressor breakdown contaminants in a plating bath |
| KR101381331B1 (ko) * | 2005-05-09 | 2014-04-04 | 테라노스, 인코포레이티드 | 현장진료 유체 시스템 및 그 용도 |
| KR101321296B1 (ko) * | 2005-07-20 | 2013-10-28 | 바이엘 헬스케어 엘엘씨 | 게이트형 전류 측정법 온도 결정 방법 |
| US20070054404A1 (en) * | 2005-09-08 | 2007-03-08 | Beckman Coulter, Inc. | Method of hemoglobin correction due to temperature variation |
| KR101477947B1 (ko) | 2005-09-30 | 2014-12-30 | 바이엘 헬스케어 엘엘씨 | 게이트형 전압 전류 측정 이온화제 및 헤마토크리트 결정 방법 |
| CN103760356B (zh) | 2007-12-10 | 2019-06-28 | 安晟信医疗科技控股公司 | 斜率式补偿 |
| JP5738770B2 (ja) | 2008-12-08 | 2015-06-24 | バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ | 信号調整を持つバイオセンサシステム |
| JP5270501B2 (ja) * | 2009-09-17 | 2013-08-21 | テルモ株式会社 | 血糖計及び血糖値測定方法 |
| US9599614B2 (en) * | 2011-03-14 | 2017-03-21 | Yale University | Calibration of nanostructure sensors |
| WO2013043839A1 (en) | 2011-09-21 | 2013-03-28 | Bayer Healthcare Llc | Biosensor with error compensation |
| TWM438626U (en) * | 2012-03-09 | 2012-10-01 | Rainbow Light Optical Co Ltd | Miniature fruit sweetness measurement device |
-
2014
- 2014-03-11 EP EP18202297.0A patent/EP3457141B1/en active Active
- 2014-03-11 JP JP2016501167A patent/JP6446023B2/ja active Active
- 2014-03-11 ES ES14730228T patent/ES2715407T3/es active Active
- 2014-03-11 WO PCT/US2014/023167 patent/WO2014159354A1/en not_active Ceased
- 2014-03-11 EP EP14730228.5A patent/EP2972398B1/en active Active
- 2014-03-11 CN CN201480025370.9A patent/CN105308461B/zh active Active
- 2014-03-11 CA CA2902545A patent/CA2902545A1/en not_active Abandoned
- 2014-03-11 US US14/775,070 patent/US9933441B2/en active Active
- 2014-03-13 TW TW107101865A patent/TWI654431B/zh not_active IP Right Cessation
- 2014-03-13 TW TW103108989A patent/TWI621852B/zh not_active IP Right Cessation
-
2015
- 2015-08-25 IL IL240817A patent/IL240817B/en active IP Right Grant
-
2018
- 2018-11-30 JP JP2018224727A patent/JP6949811B2/ja active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201120444A (en) | 2009-12-14 | 2011-06-16 | Taidoc Technology Corp | Electrochemical biosensing test strip, biosensing meter, system and measuring method for analyte measurement incorporating a hematocrit correction |
| CN102116752A (zh) | 2009-12-30 | 2011-07-06 | 生命扫描有限公司 | 使用填充时间改进生物传感器的精确度的系统、装置和方法 |
| US20110231105A1 (en) | 2010-03-22 | 2011-09-22 | Bayer Healthcare Llc | Residual Compensation Including Underfill Error |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2902545A1 (en) | 2014-10-02 |
| JP6949811B2 (ja) | 2021-10-13 |
| WO2014159354A1 (en) | 2014-10-02 |
| EP3457141B1 (en) | 2021-09-29 |
| EP3457141A1 (en) | 2019-03-20 |
| JP6446023B2 (ja) | 2018-12-26 |
| TWI621852B (zh) | 2018-04-21 |
| IL240817A0 (en) | 2015-10-29 |
| JP2016516193A (ja) | 2016-06-02 |
| TW201447301A (zh) | 2014-12-16 |
| IL240817B (en) | 2018-02-28 |
| US20160033537A1 (en) | 2016-02-04 |
| JP2019060889A (ja) | 2019-04-18 |
| CN105308461B (zh) | 2017-08-15 |
| HK1220769A1 (zh) | 2017-05-12 |
| EP2972398B1 (en) | 2018-12-19 |
| EP2972398A1 (en) | 2016-01-20 |
| US9933441B2 (en) | 2018-04-03 |
| ES2715407T3 (es) | 2019-06-04 |
| CN105308461A (zh) | 2016-02-03 |
| TW201818072A (zh) | 2018-05-16 |
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