TWI574664B - Rapid pathology test slice tool - Google Patents

Description

Rapid pathology test slicing tool

The present invention relates to a tool, and more particularly to a rapid pathology test slicing tool.

In the pathological section preparation, some tissues or organs with lesions are first sampled, and then the tissue is fixed and hardened by low-temperature freezing or using various chemicals and burial methods, and then the tissue is sliced and expanded. Adhered to the glass slide, and finally dyed the tissue sheet with the dye to complete the production process. The completed pathological section can be examined under a microscope to observe pathological changes and make a pathological report.

However, the aforementioned pathological sectioning process is complicated, especially after the tissue is sliced into a sheet, and the tissue sheet is unfolded to adhere to the slide glass, which is particularly likely to fail. Taking the pathological section of the current tumor operation as an example, the whole slice preparation process is about one week.

It can be seen that the production process of the pathological section is time-consuming and labor-intensive, and the surgeon or the pathologist can not immediately observe the pathological judgment after sampling the tissue sheet.

Accordingly, it is an object of the present invention to provide a rapid pathological inspection slicing tool that reduces the number of slicing steps and saves the time required for slicing.

Thus, the rapid pathology test slicing tool of the present invention comprises: two blades spaced apart from each other to define a gap, each blade including a blade portion and at least one through hole extending through the blade portion to communicate the gap. In each of the blades, the blade portion has an inner surface facing the gap, and an outer surface facing away from the gap, the inner surface is connected to the outer surface as a blade edge, the through hole is adjacent to the blade and penetrates the inner portion The surface corresponds to the outer surface; the positions of the through holes of the blades correspond.

The invention has the following advantages: the innovative structural design of forming the through holes on the blades is as long as it is inserted into the biological tissue to be sampled and then pulled out, and the tissue is directly embedded in the gap, which can be directly Dyeing and observation at the same hole, it is easy to operate, so that the process of freezing and cutting the slice is required to reduce the pathological section, so the time for slicing and pathological examination can be saved.

1‧‧‧Knife

2‧‧‧blade

20‧‧‧ gap

21‧‧‧Installation Department

211‧‧‧ base section

212‧‧‧ shoulder section

22‧‧‧Knife

220‧‧‧ Blade

221‧‧‧ inner surface

222‧‧‧ outer surface

23‧‧‧Tongkong

231‧‧‧Internal port

232‧‧‧External port

3‧‧‧Interval unit

31‧‧‧Stained materials

32‧‧‧Particles

‧‧‧Width

Other features and effects of the present invention will be apparent from the following description of the drawings, wherein: Figure 1 is a partial top plan view of a first embodiment of the rapid pathology test slicing tool of the present invention; A partial cross-sectional view taken along line AA of Fig. 1; and Fig. 3 is a partial cross-sectional view similar to Fig. 2 showing a partial structure of a second embodiment of the rapid pathology test slicing tool of the present invention.

Before the present invention is described in detail, it should be noted that in the following description, similar elements are denoted by the same reference numerals.

Referring to Figures 1 and 2, a first embodiment of the rapid pathology test slicing tool of the present invention comprises: a shank 1, two blades 2 spaced apart from each other on the shank 1, and a blade 2 spaced apart cell 3.

The blades 2 are symmetrically spaced apart from one another and collectively define a gap 20. Each of the blades 2 includes a mounting portion 21 assembled to the shank 1, a blade portion 22 extending outwardly from the mounting portion 21, and two through holes 23 respectively extending through the blade portion 22 to communicate the gap 20. The positions of the through holes 23 of the blades 2 overlap.

In each of the blades 2, the mounting portion 21 has a base portion 211 mounted to the shank 1 and having a width larger than the blade portion 22, and a shoulder portion 212 connected between the base portion 211 and the blade portion 22. . The width of the shoulder section 212 is gradually narrowed from the end connecting the base section 211 toward the end connecting the blade portion 22. The blade portion 22 is in the form of a double slope, and the blade portion 22 has an inner surface 221 facing the gap 20 and an outer surface 222 facing away from the gap 20. The inner surface 221 is connected to the outer surface 222 as a blade 220. The through holes 23 are adjacent to the blade 220 and extend through the inner surface 221 and the outer surface 222.

Each of the through holes 23 has an inner port 231 adjacent to the gap 20, and an outer port 232 remote from the gap 20. The diameter of each of the through holes 23 is gradually enlarged from the inner port 231 toward the outer port 232.

The width d of the gap 20 can be arbitrarily adjusted to achieve the desired view In view of the requirements of the biological tissue cells, the width d of the gap 20 can be adjusted and customized according to the needs of the pathologist for the biological tissue, and there is no need to be particularly limited.

The spacing unit 3 includes an anister disposed on the blades 2 The rubber material 31 between the mounting portions 21 and the plurality of particles 32 blended in the rubber material 31 and supported between the mounting portions 21. The material of the rubber material 31 may specifically be a thermoplastic adhesive or other polymer adhesive material having a bonding function, such as a photoresist liquid; the material of the microparticles 32 is specifically a micron-sized glass bead or a polymer bead. The gap 20 can also be defined by other materials, such as photoresist, to define its width d.

It should be noted that, in use, the blades 2 are spaced apart. When the ground is mounted on the shank 1, the gap 20 can be created between the blades 2, so the rapid pathological inspection dicing tool is not necessary to provide the spacing unit 3.

Further, this embodiment fills the gap 20 with the glue material. 31. In addition to the structure that can assist in stabilizing the blades 2, the thickness of the glue 31 can be changed by adjusting the amount of the glue 31, and the width d of the gap 20 can be conveniently adjusted. More preferably, in this embodiment, the particles 32 of predetermined particle size are selected to be blended in the rubber material 31, and the blades 2 are pressed to sandwich the blades 2 against the particles 32, so that the adjustment can be conveniently adjusted. The width d of the gap 20.

In addition, the handle 1 can be held by the user as long as it is held. The specific form of the shank 1 need not be limited in practice. In implementation, it can also The blades 2 are directly mounted to a machine arm or the like, thereby automatically sampling and precisely controlling the sampling position. In other words, the rapid pathological inspection slicing tool is not necessary to set the shank 1.

In use, the rapid pathological test slicing tool is quickly inserted Immediately after the biological tissue to be sampled is taken out. Inserting the rapid pathological test slicing tool into the present, cutting through the blades 2, a part of the tissue sheet can be embedded and clamped in the gap 20, and after the rapid pathological examination slicing tool is pulled out, the gap 20 is removed. The tissue is sliced and the process of sampling and slicing is completed. Finally, after the dyeing agent is directly dropped into the through holes 23 to perform the dyeing process, the tissue sheets can be directly inspected and observed through the through holes 23 for immediate pathological determination.

As can be seen from the above description, compared to the traditional pathological section The process is cumbersome, time-consuming and labor-intensive. Using the rapid pathological examination of the cutting tool of this embodiment, as long as it is inserted into the biological tissue to be sampled and pulled out, it can be dyed and observed immediately, and the operation is simple, thereby reducing the need for pathological sectioning. The process of freezing and cutting the sheet can save time for slicing and pathological examination. Therefore, the present embodiment can be extended to the pathology department of major hospitals as one of the methods for rapid examination of tissue cells, so that the doctor or pathologist can immediately sample the tissue slices, and the pathologist immediately makes a pathological report.

In addition, the aperture of each of the through holes 23 of the embodiment is from the inside The port 231 is gradually enlarged toward the outer port 232. The foregoing structure is designed to facilitate the dripping of the dye into the through holes 23, and the user can conveniently observe the tissue sheet from the through holes 23.

As for the blade portion 22 of each blade 2 of the present embodiment, it is double In the oblique form, therefore, the pitch of the blade edges 220 of the blade portions 22 is large. In other words, the gap 20 is larger adjacent the opening at the blades 220 to facilitate entry of biological tissue.

In use, the number of the through holes 23 of each of the blades 2 may be one or two or more, which may be increased or decreased according to requirements, and is not limited to the form disclosed in the embodiment.

Referring to Fig. 3, a second embodiment of the rapid pathological examination slicing tool of the present invention is substantially the same as the first embodiment, and the difference between the two is that the blade portion 22 of each blade 2 of the present embodiment is monoclinic. In the form of the outer surface 222 of the blade portion 22, the angle of the outer surface 222 of the blade portion 22 is relatively easy to fix in the polishing and polishing operation, and the manufacturing process is relatively simple, and the blade edge 220 is also sharpened.

However, the above is only the embodiment of the present invention, and the scope of the present invention is not limited thereto, that is, the simple equivalent changes and modifications made by the patent application scope and the patent specification of the present invention are still It is within the scope of the patent of the present invention.

2‧‧‧blade

20‧‧‧ gap

21‧‧‧Installation Department

22‧‧‧Knife

220‧‧‧ Blade

221‧‧‧ inner surface

222‧‧‧ outer surface

23‧‧‧Tongkong

231‧‧‧Internal port

232‧‧‧External port

3‧‧‧Interval unit

31‧‧‧Stained materials

32‧‧‧Particles

‧‧‧Width

Claims (9)

A rapid pathological inspection slicing tool comprising: two blades spaced apart from each other to define a gap, each blade including a blade portion, and at least one through hole extending through the blade portion to communicate the gap; in each blade, The blade portion has an inner surface facing the gap, and an outer surface facing away from the gap, the inner surface is connected to the outer surface as a blade edge, the through hole is adjacent to the blade edge and penetrates the inner surface and the outer surface The position of the through holes of the blades corresponds to each other. The rapid pathology test slicing tool of claim 1, wherein the through hole of each blade has an inner port adjacent to the gap, and an outer port away from the gap; the aperture of the through hole of each blade is The inner port is gradually enlarged toward the outer port. The rapid pathology test slicing tool of claim 1, wherein the blade portion of each blade is in the form of a single oblique. The rapid pathology test slicing tool of claim 1, wherein the blade edge portion of each blade is in the form of a double slope. The rapid pathology test slicing tool of claim 1, wherein each blade comprises a plurality of through holes. The rapid pathology test slicing tool according to any one of claims 1 to 5, further comprising a spacing unit for spacing the blades from each other. The rapid pathology test slicing tool of claim 6, wherein each of the blades further includes a mounting portion extending from the blade portion to the spacer unit; the spacer unit including a mounting portion disposed on the blades The glue between them. The rapid pathology test slicing tool of claim 7, wherein the spacer unit further comprises a plurality of particles incorporated in the glue material, the particles being supported between the mounting portions of the blades. The rapid pathology test slicing tool of claim 6, wherein each of the blades further includes a mounting portion extending from the blade portion to the spacer unit; the rapid pathology slicing tool further includes a mounting portion for the blades Assembly of the handle.