TWI574654B - Systems for improving upper airway patency - Google Patents

Description

System for improving upper airway patency

The present invention relates to a medical device for improving the quality of sleep breathing and a method of using the same; and the present invention relates to a system and method for improving the patency of upper airway during sleep.

Obstructive Sleep Apnea (OSA), hypopnea (hypopnea), and Upper Airway Resistance Syndrome (UARS) are completely or partially blocked by the upper respiratory tract during sleep, during anesthesia, or after anesthesia. The various symptoms that cause the interruption of breathing during sleep and the potential for severe oxygen deficiency in the blood. Patients with OSA, hypopnea and/or UARS are often repeatedly awakened due to insufficient oxygen during sleep, resulting in fragmental sleep and poor sleep quality. Some structures inside the patient's mouth, such as the tongue, soft palate and uvula, may move toward the upper airway, causing the patient's upper airway to block, and the patient's sleep posture often affects the direction of movement of these oral structures, especially When the patient is lying supine, the patient's face is facing directly above, and when the head is in a position, the gravity pulls the oral structures to the upper respiratory tract, causing the patient's upper airway to be narrowed or even blocked. When the patient is sleeping on his side, the patient's face is facing to one side, and in this head position posture, gravity will not bring these oral structures. Pulling directly to the upper airway has less effect on the patient's upper airway narrowing or occlusion.

Positional therapy uses the supine posture of patients with sleep-disordered breathing to slow down the severity of sleep-disordered breathing. The posture therapy has the advantages of simplicity and low side effects, but some patients cannot lie on their back due to back disease or cervical pain. , posture therapy can not be applied to such patients. The posture treatment method can only improve the respiratory obstruction caused by a specific part, and the treatment effect is limited, and the discomfort such as backache caused by prolonged lying on the side greatly affects the compliance of the posture treatment method.

There are currently several treatments for patients with sleep-disordered breathing. The most common treatment is the Constant Positive Airway Pressure (CPAP) Machine. Positive pressure breathing apparatus consists of a mask, a pump and a humidifier. The positive pressure respirator continuously blows high pressure air into the patient's nasal passages to keep the patient's airway clear during sleep. Positive pressure respirators are quite effective, but they can cause unpleasant side effects such as dry throat and blocked nasal passages. Patients who use positive pressure respirators often experience swelling and headaches in the morning. It has low adaptability due to the serious side effects it causes. An improved treatment method known at present is to apply a negative pressure in the patient's mouth, and use a negative pressure to pass into the front end of the patient's mouth, usually at the lip or the lip later, by pulling the tongue forward with a negative pressure to pull The rear end of the tongue is moved away from the posterior wall of the respiratory tract to prevent the patient's tongue from collapsing and blocking the upper respiratory tract.

Referring to the first figure, when the patient takes a supine posture during sleep but the head posture is incorrect, the soft palate 33 is displaced toward the upper airway 37, causing the upper airway 37 to narrow to a distance d, even causing obstruction of the upper airway. In this case, the patient's effect of making the upper airway 37 unblocked is limited even if the patient is given oral negative pressure therapy. On the other hand, as shown in the second figure, when the patient slumbers and adjusts the head to the correct posture, the soft palate 33 is pulled upwards away from the upper airway 37, and The distance D between the front and rear walls of the upper airway 37 can be increased, but it is still necessary to transmit through the oral negative pressure to stabilize the soft palate 33 in order to truly clear the respiratory tract.

According to the above, the medical equipment industry urgently needs to provide a mechanism for patients to perform posture therapy in a supine posture combined with negative pressure therapy, in order to provide a safer and more comfortable sleep quality for patients with sleep apnea.

It is an object of the present invention to provide a relative angle range that can maintain a user's supine posture and adjust the head, neck and shoulders of the user to the most suitable for negative pressure breathing therapy and combined with negative pressure breathing therapy to improve sleep of the user. A system and method for upper airway patency during the period.

In accordance with the foregoing objects of the present invention, an aspect of the present invention provides a system for improving patency of an upper airway, the system comprising an angular positioning unit, a mouth interface unit, and a vacuum source. The angle positioning unit is configured to adjust a relative angular range of the head, the neck and the upper torso of the user during sleep to the most suitable negative pressure breathing therapy, and then provide a negative pressure to the oral interface unit through the vacuum source for delivery to the oral cavity. To create and maintain a sealed negative pressure environment in the user's mouth, and then use the negative pressure to move the tongue and the soft palate to the front and the top of the mouth to increase the distance between the soft palate and the base of the tongue and the back wall of the throat to improve The upper airway patency of the user during sleep is maintained.

The foregoing relative angle range most suitable for negative pressure breathing therapy includes a head angle θhead and a torso angle θtorso, which is defined as an angle between a neck center line and a straight line connecting the person to the highest point of the nasal bone, wherein the center of the neck is The line to the highest point of the nose is defined as a positive angle when it is a clockwise angle, and a negative angle when it is a counterclockwise angle. The torso angle θtorso is defined as the angle between the neck centerline and the trunk centerline. When the center line of the neck to the centerline of the trunk is a clockwise angle, it is defined as a positive angle, and when it is a counterclockwise angle Righteousness is a negative angle. In order to achieve the optimal posture treatment angle in the supine position, the angle positioning unit is designed to control the head angle θhead within a range of -40 degrees to 10 degrees, and the torso angle θtorso is controlled in the range of -10 degrees to 30 degrees. in. The design of the angle positioning unit can be customized according to different user body types.

In an embodiment of the invention, the system of the present invention further includes a controller for controlling the angular positioning unit and the vacuum source.

In an embodiment of the invention, the angle positioning unit comprises at least one deformable support structure selected from the group consisting of a head support structure, a left side support structure, a right side support structure, a neck support structure, and a shoulder support. Structure, neck/shoulder support and combinations thereof. In the present invention, the aforementioned neck/shoulder support structure refers to a member that supports the neck and the shoulder. In an embodiment of the present invention, the angle positioning unit may be implemented by a pillow structure internally provided with the deformable support structure, and the deformable support structure may be any of the following: the head supports the air, the left side supports Airbag, right side support airbag, neck support airbag, shoulder support airbag, neck/shoulder support airbag, and combinations thereof. In this embodiment, the present invention can adjust the height of the user's head by transmitting gas to the head support airbag, and the user's head can be adjusted to the right side by transmitting gas to the left support airbag, preferably Turn right 30 degrees to 60 degrees, you can adjust the user's head to the left by transmitting gas to the right support airbag, preferably 30 degrees to 60 degrees to the left, and support the airbag and shoulder support through the neck. The balloon or the neck/shoulder support balloon can adjust the neck extension angle of the user. In other words, in this embodiment, the present invention supports the airbag in the interior of the pillow through the filling gas to adjust the position of the user's head, neck and upper torso, thereby changing the moving direction of the user's tongue, soft palate, etc., so that the user The distance between the anterior and posterior wall of the upper airway can be increased to improve the effect of negative pressure sleep therapy.

In an embodiment of the invention, the deformable support structure may be Any of the following: a head support air bag, a left side support air bag, a right side support air bag, a neck support air bag, a shoulder support air bag, a neck/shoulder support air bag, and combinations thereof. By transferring the gas to the aforementioned support air bag, or extracting the gas from the aforementioned support air bag, the air pressure in the air bag is changed, thereby causing the air bag to expand or compress, to adjust the height of the user's head, and to adjust the user to rotate to the right side. Adjust the user to turn to the left or adjust the extension angle of the user's neck. The foregoing supporting airbag is a flexible material layer which can be deformed in response to a pressure change when the gas pressure transporting unit delivers the gas to or from the airbag, and the material layer constituting the airbag is, for example, A layer of a polymer material layer, a latex material layer, a silicone material layer or a combination of the above.

In an embodiment of the invention, the deformable support structure is formed by a support balloon defined by an outer wall. The air pressure in the support air bag is changed by transferring the gas to the support air bag or from the air bag, and the air bag is inflated or compressed to adjust the height of the user's head, for example, the user's head is placed on the head. When the support structure is deformable, when the airbag constituting the deformable support structure is inflated, the volume of the airbag is increased, so that the head of the user located thereon is increased, and the volume of the airbag is reduced when the airbag is compressed and compressed. So that the head of the user located thereon is lowered; or the user's head can be adjusted to the right by transmitting gas to the left support airbag, or the user's head can be adjusted by transmitting gas to the right support airbag. The user's neck extension angle can be adjusted by turning to the left side or through the neck support balloon, shoulder support balloon or the neck/shoulder support balloon. The outer wall is a layer of flexible material. When the gas pressure conveying unit transports the gas to the supporting air bag, the outer wall can be deformed according to the pressure change, and the material layer constituting the outer wall is, for example, a polymer material layer. a layer of material consisting of a layer of latex material, a layer of silicone material or a mixture of the above.

In an embodiment of the invention, the support airbag includes an outer wall and a bladder disposed therein. When the gas pressure delivery unit delivers the gas to the support air bag, the positive pressure inside the support air bag is increased; or, when the gas pressure delivery unit sucks the gas out of the support air bag, a negative pressure is generated on the support air bag. Therefore, the expansion or compression of the supporting airbag is caused, and the outer wall or the inner tank can be deformed in response to the change of the gas pressure, thereby adjusting the height of the user's head; for example, when the user's head is placed on the deformable support structure, When the airbag constituting the deformable support structure is inflated, the volume of the airbag is increased, so that the head of the user located thereon is increased, and when the airbag is compressed, the user located thereon is reduced due to the volume reduction of the airbag. The head is therefore lowered. The inner tank may be a pore structure that provides a gas circulation space and supports the outer shape defined by the outer wall, including but not limited to: an expandable polymer structure, a foam structure, a porous latex structure, and a porous tantalum structure. Body, natural fiber structure, rayon structure or a combination of the above.

In an embodiment of the invention, the controller includes a gas pressure delivery unit that provides positive pressure to the angular positioning unit to adjust at least one position of the user's head, neck and shoulder positions. In an embodiment of the invention, the gas pressure delivery unit includes a gas pressure delivery selector to control a positive pressure delivery path of the gas pressure delivery unit.

In an embodiment of the invention, the controller includes a gas pressure delivery unit that provides a negative pressure to the angular positioning unit to adjust at least one position of the user's head, neck and shoulder positions.

In an embodiment of the invention, the system of the present invention further includes a head position sensor for detecting the position of the head of the user and transmitting a head position signal to the controller. In an embodiment of the invention, the head position sensor is selected from the group consisting of an accelerometer, a pressure sensor, a load sensor, and a pressure sensor.

In an embodiment of the invention, the system of the present invention further includes a respiratory state sensor for detecting the breathing state of the user. In an embodiment of the invention, the respiratory state sensor is selected from the group consisting of: a respiratory flu detector, a respiratory airflow pressure sensor, a microphone snoring sensor, a respiratory airflow temperature sensor, and blood. Oxygen meter. In an embodiment of the invention, the respiratory state sensor is configured to detect a flow resistance of the user's respiratory airflow. In this embodiment, the user's respiratory airflow resistance is presented as a snoring map or a respiratory airflow pattern.

In an embodiment of the invention, the system of the present invention further comprises a liquid storage tank disposed between the controller and the oral interface unit to collect a saliva of the user. In an embodiment of the invention, the negative pressure value in the oral cavity of the user is -20 mmHg to -60 mmHg.

In another aspect, the present invention provides a method for improving upper patency of a lower respiratory tract, comprising the steps of: setting a relative angular range of a head, a neck, and a shoulder that is most suitable for negative pressure breathing therapy when the user sleeps; The neck and the shoulder are most suitable for the relative angular range of the negative pressure breathing treatment, adjusting the sleep posture of the user; transmitting a negative pressure to the inside of the user's mouth to create a sealed negative pressure environment inside the user's mouth; and maintaining the The inside of the user's mouth is sealed in a negative pressure environment, and then the negative pressure in the mouth is used to move the tongue and the soft palate to the front and the top of the mouth to increase the distance between the soft palate and the base of the tongue and the back wall of the throat to improve the upper respiratory tract of the user. Unobstructed.

In an embodiment of the invention, the user adjusts the sleep posture of the user according to the relative angle range of the head, the neck and the shoulder which are most suitable for the negative pressure breathing treatment during sleep, and the user can be supported by the expandable/compressed airbag. At least one of the head, neck and shoulders and delivering gas to the expandable/compressible bladder is achieved.

The aforementioned relative angle range most suitable for negative pressure breathing therapy includes the head Angle θhead and torso angle θtorso, the head angle θhead is defined as the angle between the center line of the neck and the line connecting the highest point of the nose and the nose, wherein the line from the center line of the neck to the highest point of the nose and the nose is clockwise. The angle is defined as a positive angle, and when it is a counterclockwise angle defined as a negative angle, the torso angle θtorso is defined as the angle between the neck centerline and the torso centerline, where the clockwise angle from the neck centerline to the trunk centerline is Defined as a positive angle, defined as a negative angle when the angle is counterclockwise. In an embodiment of the invention, the head angle is in the range of -40 to 10 degrees in the relative angle most suitable for negative pressure breathing therapy. In an embodiment of the invention, the torso angle ranges from -10 degrees to 30 degrees in the relative angle most suitable for negative pressure breathing therapy. In an embodiment of the invention, the adjusting the user's sleep posture to a relative angle most suitable for the negative pressure breathing treatment comprises controlling the user's head to turn right 30 degrees to 60 degrees or the user's head turning left 30 degrees. To 60 degrees.

In an embodiment of the invention, the method of the present invention further includes a head position parameter measuring step for detecting the position of the head of the user. In an embodiment of the invention, the head position parameter is selected from any of the following: acceleration, pressure, load, and piezoelectric change.

In an embodiment of the invention, the method of the present invention further comprises a breathing detection step for detecting a breathing state of the user. In an embodiment of the invention, the respiratory state is selected from the group consisting of: respiratory airflow, respiratory airflow pressure, snoring, respiratory airflow temperature, and blood oxygen concentration.

In one embodiment of the invention, the method of the invention maintains a negative pressure within the oral cavity of the user between -20 mmHg and -60 mmHg.

10, 100, 110, 120, 130, 140, 150, 900‧‧‧ pillow body

12‧‧‧ Deformable head support structure

14‧‧‧Deformable shoulder support structure

20‧‧‧ Controller

31‧‧‧Software

33‧‧‧ tongue

35‧‧‧The back wall of the throat

37‧‧‧ upper respiratory tract

92‧‧‧Respiratory sensor

94‧‧‧ head position sensor

96‧‧‧ Controller

97‧‧‧ liquid storage tank

98‧‧‧Mouth interface unit

102‧‧‧ Deformable right side support structure

104‧‧‧ deformable left support structure

106‧‧‧ deformable neck support structure

112, 114‧‧‧ neck support pillow

122, 122a, 122b‧‧‧ gas pipeline

124‧‧‧ Positive pressure pump

125‧‧‧Negative pressure pump

126‧‧‧Switching control valve

201~206‧‧‧ gas pipeline

902‧‧‧ Deformable right side support structure

904‧‧‧ Deformable left support structure

906‧‧‧ deformable neck support structure

960, 962, 964, 970‧‧‧ gas pipelines

960, 962, 964‧‧‧ gas pipeline

966, 968‧‧‧ electrical connection lines

972‧‧‧vacuum source

980‧‧‧Airflow conduit

990‧‧‧Air passage

992‧‧‧Air passage

1001~1006‧‧‧Steps

1100‧‧‧ Deformable head support airbag

1102‧‧‧ deformable neck/shoulder support airbag

1104‧‧‧ Deformable left side support airbag

1202‧‧‧Neck/shoulder support airbag

1204‧‧‧ head support airbag

1206‧‧‧ accommodation space

1302‧‧‧Neck/shoulder support airbag

1304‧‧‧ head support airbag

1306‧‧‧Accommodation space

1402, 1502‧‧‧ deformable right side support structure

1404, 1504‧‧‧ deformable left support structure

1406, 1508‧‧‧ deformable shoulder support structure

1506‧‧‧ deformable neck support structure

1901~1903‧‧‧Steps

9601‧‧‧Microprocessor

9602‧‧‧Exhaust pump

9603‧‧‧First switching control valve

9604‧‧‧ gas pressure delivery selector

9605‧‧‧pressure sensor

9606‧‧‧ check valve

9607‧‧‧Second switching control valve

The first picture shows that the patient's head posture is incorrect when lying on his back, resulting in a narrow upper airway. Schematic diagram of the first embodiment of the present invention; FIG. 3A to FIG. 3D are various views of the first embodiment of the angular positioning unit of the present invention, wherein the third diagram is a schematic view of the first embodiment of the present invention; The angle positioning unit is realized by a pillow structure; the fourth figure shows a side view of the user in a supine state on the pillow of the third figure; the fifth figure shows that the user is lying on the pillow of the third figure and passes through the pillow. A side view showing the position of the head, the neck and the upper torso; the sixth drawing shows a side view of the user adjusting the head, the neck and the upper torso through the pillow of the third figure to make the user's head reclined; Figure 6B shows a side view of the upper airway widening when the user takes the sleep posture of Figure 6A; Figure 7A shows the user adjusting the head, neck and upper torso position of the head through the pillow of the third figure. FIG. 7B is a side view showing a narrowing of the upper airway when the user adopts the sleep posture of FIG. A; FIGS. 8A to 8D are angle positioning units of the present invention. A schematic diagram of various variations of the first embodiment; ninth to ninth C is a schematic view of various aspects of a first embodiment of the angular positioning unit of the present invention; A schematic view of still another variation of a specific embodiment; FIG. 11 is a schematic view of a second embodiment of the angular positioning unit of the present invention, wherein the angular positioning unit is implemented by another pillow structure; a schematic view of the pillow lying on the eleventh figure for the user; Figure 12B shows a schematic diagram of the relative positions of the tongue, soft palate and the posterior wall of the throat when the user of Figure 12A does not suffer from sleep-disordered breathing; Figure 12C shows when the Twelfth A The user is suffering from sleep-disordered breathing, and the relative position of the tongue, the soft palate and the posterior wall of the throat; the 13th A is the user lying on the pillow of the eleventh figure and adjusting the user's head through the pillow Schematic diagram of the state of turning left to the left; Figure 13B shows the relative position of the tongue, soft palate and the posterior wall of the throat when the user of the thirteenth A diagram does not suffer from sleep-disordered breathing; The figure shows a schematic diagram of the relative position of the tongue, the soft palate and the posterior wall of the throat when the user of the thirteenth A diagram has the symptoms of sleep apnea; the fourteenth A is the user lying on the pillow of the eleventh figure and Through the pillow, the state of the user's head is turned to the right; FIG. 14B shows that when the user of the fourteenth A-A diagram does not suffer from sleep-disordered breathing, the tongue, the soft palate and the posterior wall of the throat Relative position diagram; fourteenth C picture A diagram showing the relative position of the tongue, the soft palate and the posterior wall of the throat when the user of FIG. 14A has a sleep apnea symptom; FIG. 15 is a variation of the second embodiment of the angle locating unit of the present invention. A schematic diagram of an example, the variation is implemented in a pillow structure; and a sixteenth view is a schematic view of another variation of the second embodiment of the angular positioning unit of the present invention, the variation being implemented by a pillow structure; A schematic diagram of still another variation of the second embodiment of the angular positioning unit of the present invention, wherein a breathing state sensor and a head position sensor are further provided in the variation; and the eighteenth drawing is the use of the seventeenth The angle locating unit determines a flow chart of the steps for the user to optimize the position of the head; FIG. 19 is a schematic view of the first embodiment of the system for improving the patency of the upper airway of the present invention; Figure 20 is a schematic view showing a second embodiment of the system for improving upper patency of the upper respiratory tract; and the twenty-first embodiment is a schematic diagram of applying sleep breathing therapy to a user using the system of the second embodiment of the twentieth embodiment. Figure 22 is a flow chart showing the steps of applying sleep breathing therapy to the user using the second embodiment system; and Fig. 23 is a second embodiment of the system for detecting the user relative to the head thereof The bottom of the pillow is optimized for the position of the head; the twenty-fourth is a schematic diagram for detecting the position of the head of the user with respect to the head of the pillow below the head and performing oral negative pressure treatment using the second embodiment; The figure is a schematic diagram of the oral negative pressure treatment of the user using the system of the second embodiment; the twenty-sixth A is a schematic diagram of a variation of the system of the second embodiment of the present invention; and the twenty-sixth B is a user A side view of the supine sleep posture is performed using the system of the twenty-sixth A diagram; the twenty-sixth C is a side view of the neck/shoulder elevation sleep posture by the user using the twenty-sixth A-A system; A picture A schematic diagram of another variation of the system of the second embodiment of the present invention; FIG. 17B is a schematic side view of the user using the twenty-seventh A system in a supine sleep posture; A schematic view of a sleep posture in which the head of the system is rotated to the left side using the twenty-seventh A-A system; FIG. 28A is a schematic view showing still another variation of the system of the second embodiment of the present invention; For the user to use the twenty-eighth A map system, head back to sleep A side view of a sleep posture, and a twenty-ninth figure are schematic views of still another variation of the system of the second embodiment of the present invention.

The objects, spirits and advantages of the invention will be apparent from the description of the appended claims.

The third A is a schematic view of a first embodiment of the present invention having an angular positioning unit for adjusting the position of the head, neck and shoulders of the user during sleep. The first embodiment is implemented by a pillow structure. The third B is a front view of the third A, and the third C is a cross-sectional view of the third A along the I---I' line and the third D is perpendicular to the I--I' line. Schematic diagram of the section. In a first embodiment, the angle positioning unit of the present invention mainly includes a pillow body 10 and a controller 20. The pillow body 10 is internally provided with a deformable head support structure 12 and a deformable shoulder support structure 14. In one embodiment of the invention, the deformable head support structure 12 and the deformable shoulder support structure 14 can be constructed from an expandable/compressible bladder. The controller 20 has a gas pressure delivery unit (not shown) with gas lines 202, 204 respectively communicating with the deformable head support structure 12 and the deformable shoulder support structure 14 such that the gas pressure delivery unit can An appropriate amount of gas is delivered to any of the deformable head support structure 12 and the deformable shoulder support structure 14 as needed. In some embodiments of the present invention, the deformable head support structure 12 and the deformable shoulder support structure 14 may be formed of a porous gas-fillable material, for example, the deformable head support structure 12 and deformable. The shoulder support structure 14 can be selected from any of the following: foam material parts, latex material parts, natural fiber parts, and rayon parts.

The fourth figure shows a schematic view of the side view of the user when lying on the pillow body 10. In the present invention, "shoulder" means that the user faces the face with respect to the pillow below the head. The fifth figure shows that the present invention can adjust the head relative height H _{head of} the pillow body 10 by filling a suitable amount of gas into the deformable head support structure 12 or the deformable shoulder support structure 14 or both. The relative height of the _neck, H _neck, and the relative height of the _shoulder , H _shoulder , adjust the relative angle of the head, neck and upper torso of the user to the most suitable for negative pressure breathing therapy. The relative angular range most suitable for negative pressure breathing therapy in the present invention comprises a head angle θhead defined as a neck center line N---N' and a highest point in the person and the nose bone angle θtorso The angle between the line H---H', which is defined as a positive angle from the center line of the neck to the straight line connecting the highest point of the nose and the human nose, and a negative angle when the angle is counterclockwise, the torso The angle θtorso is defined as the angle between the neck centerline N---N' and the trunk centerline T---T', where a positive angle is defined from the neck centerline to the trunk centerline when it is clockwise. The hour hand angle is defined as a negative angle. In order to achieve the optimal posture treatment angle in the supine position, the angle positioning unit of the first embodiment is designed to control the head angle θhead within a range of -40 degrees to 10 degrees, and the torso angle θtorso is controlled at -10. Degree to 30 degrees. The design of the angle positioning unit can be customized according to different user body types.

Figure 6A shows the user's head in a reclined posture as the filling gas lifts the user's shoulder at the deformable shoulder support structure 14. 6B is a schematic view showing the relative position of the tongue 31, the soft palate 33 and the upper airway 37 of the user of FIG. A. It can be seen that the user can make the user adjust the user's sleep posture through the angle positioning unit of the pillow pattern. The tongue 31 and the soft palate 33 are displaced away from the posterior wall of the upper callway 37, which facilitates widening the distance between the front and rear walls of the upper airway 37. However, it is worth noting that the present invention maintains the state of the upper airway 37 of the sixth B diagram during the supine sleep, and the present invention still needs to stabilize the position of the tongue 31 and the soft palate 33 through the oral negative pressure to facilitate use. The person maintains the patency of the upper airway 37 during sleep. Figure 7A shows when the filling gas is in the When the deformable head support structure 12 raises the user's head, the user's head assumes a forward posture. 7B is a schematic view showing the relative position of the tongue 31, the soft palate 33 and the upper airway 37 of the user of FIG. A. It can be seen that the tongue 31 and the soft palate 33 of the user are displaced toward the rear wall of the upper exhalation channel 37, resulting in displacement. The distance between the front and rear walls of the upper airway 37 is narrowed.

The eighth embodiment is a first variation of the first embodiment of the angle positioning unit of the present invention. The first embodiment of the present invention includes a pillow body 110. The pillow body 110 is internally provided with a deformable neck/shoulder support airbag 1102 that passes through a gas line. 122 is connected to a controller 96. In a first variation, the present invention changes the height of the deformable neck/shoulder support balloon 1102 by introducing a gas into the deformable neck/shoulder support balloon 1102, thereby changing the neck angle of the user to adjust the use. The head, neck and shoulders are the range of relative angles most suitable for negative pressure breathing therapy. The eighth modification is a second variation, which includes a pillow body 110. The pillow body 110 is internally provided with a deformable left side support air bag 1104 that communicates with the controller 96 through a gas line 122. In a second variation, the present invention rotates the head of the user to the right side by introducing a gas into the deformable left side support air bag 1104 to change the relative position of the user's tongue, soft palate and upper airway. Improve the upper airway patency of the user. The eighth C is a third variation comprising a neck support pillow 112 made of a foam/sponge material. In a third variation, the controller 96 has a positive pressure pump 124 that communicates with the neck support pillow 112 through a gas line 122, and the controller 96 further has a switch valve 126. To control the direction of the gas flow of the gas line 122. In the third variation, the present invention can transmit an appropriate amount of gas to the neck support pillow 112 through the positive pressure pump 124 to adjust the height of the neck support pillow 112, thereby adjusting the neck extension angle of the user. The user's head, neck and shoulders are the range of relative angles most suitable for negative pressure breathing therapy. When you want to lower the neck support pillow The height of 112 can be changed through the switching valve 126 to change the direction of the gas flow of the gas line 122 so that the gas filled inside the neck support pillow 112 can be drained to the surrounding environment. The eighth D is a fourth variation comprising a neck support pillow 114 having a gas filled air bag therein. In a fourth variation, the controller 96 has a negative pressure pump 125 that communicates with the neck support pillow 114 through a gas line 122, and the controller 96 further has a switch valve 126. To control the direction of the gas flow of the gas line 122. In the fourth variation, the present invention can adjust the height of the neck support pillow 114 through the negative pressure pump 124, thereby adjusting the neck extension angle of the user, so that the user's head, neck and shoulder are optimally adapted. The relative angular range of negative pressure breathing therapy. In the fourth variation, the flow direction of the gas line 122 can also be changed through the switching valve 126 to recover the gas filled inside the neck support pillow 114.

The ninth embodiment is a fifth variation, which includes a pillow body 120. The pillow body 120 is internally provided with a neck/shoulder support air bag 1202, a head support air bag 1204, and a receiving space 1206. The accommodation space 1206 can be used to house the controller 96, a liquid storage tank, or a user's personal belongings such as a mobile phone or the like. Figure IX is a side view of the ninth A diagram and a ninth C diagram is a perspective view of the ninth A diagram. The tenth figure is a sixth variation, which includes a pillow body 130. The pillow body 130 is internally provided with a neck/shoulder support air bag 1302, a head support air bag 1304 and a receiving space 1306. The neck/shoulder support air bag 1302 and the head support air bag 1304 both extend to the outside of the pillow 130.

Figure 11 is a schematic view of a second embodiment of the angular positioning unit of the present invention. The second embodiment differs from the first embodiment in that the two adopt different pillow structures. The second embodiment includes a deformable right side support structure 102, a deformable left side support structure 104 and a deformable neck. The pillow body 100 of the support structure 106. In an embodiment of the invention, The deformable right side support structure 102, the deformable left side support structure 104, and the deformable neck support structure 106 can be constructed from an expandable/compressible bladder. The controller 20 has a gas pressure delivery unit (not shown) with gas lines 201, 203, 205 communicating with the deformable right side support structure 102, the deformable left side support structure 104, and the deformable neck support structure, respectively. 106 such that the gas pressure delivery unit can deliver an appropriate amount of gas to the deformable right side support structure 102, the deformable left side support structure 104, and the deformable neck support structure 106, as desired. In some embodiments of the present invention, the deformable right side support structure 102, the deformable left side support structure 104, and the deformable neck support structure 106 may be formed of a porous gas-fillable material, for example, the deformable The right side support structure 102, the deformable left side support structure 104, and the deformable neck support structure 106 can be selected from any of the following: foam material parts, latex material parts, natural fiber parts, and rayon parts.

Figure 12A is a schematic view showing the state of the user lying on the pillow body 100 without being filled with gas. Figure 12B shows a schematic diagram of the relative position of the tongue 31, the soft palate 33 and the posterior wall of the throat 35 when the user of the twelfth A diagram does not suffer from sleep apnea symptoms, the user's tongue 31, soft palate 33 does not collapse downward, and the user can maintain the smoothness of the upper airway 37 while lying on his back. Figure 12C shows a schematic view of the relative position of the tongue 31, the soft palate 33 and the posterior wall of the throat 35 when the user of the twelfth A diagram has symptoms of sleep apnea, and the tongue 31 and the soft palate 33 of the user can be seen. Both will collapse toward the posterior wall of the upper respiratory tract 37, causing the upper airway 37 to block.

Figure 13A shows the user lying on the pillow body 100, and the deformable right side support structure 102 is filled with gas to rotate the user's head to the left by an angle θ _L with the head and the pillow body located below. A schematic representation of the relative position of 100. Figure 13B shows a schematic diagram of the relative position of the tongue 31, the soft palate 33 and the posterior wall 35 of the throat when the user of the thirteenth A diagram is not suffering from sleep apnea, the user's tongue 31, soft palate 33 does not collapse downward, and the user can maintain the smoothness of the upper airway 37 while lying on his back. Figure 13C shows a schematic view of the relative position of the tongue 31, the soft palate 33 and the posterior wall of the throat 35 when the user of the thirteenth A diagram has a sleep apnea symptom, and the user's tongue 31 and soft palate can be seen. 33, although it collapses downward, but moves the user's tongue 31 and soft palate 33 by changing the position of the head, so that the upper airway 37 can maintain a certain degree of smoothness.

Figure 14A shows the user lying on the pillow body 100, and the deformable left side support structure 104 is filled with gas to rotate the user's head to the right by an angle θ _R with the head and the pillow body located below. A schematic representation of the relative position of 100. Figure 14B shows a schematic diagram of the relative position of the tongue 31, the soft palate 33 and the posterior wall of the throat 35 when the user of the fourteenth A diagram does not suffer from sleep apnea symptoms, the user's tongue 31, soft palate 33 does not collapse downward, and the user can maintain the smoothness of the upper airway 37 while lying on his back. Figure 14C shows a schematic view of the relative position of the tongue 31, the soft palate 33 and the posterior wall of the throat 35 when the user of the fourteenth A diagram has the symptoms of sleep apnea, and the tongue 31 and the soft palate of the user can be seen. 33, although it collapses downward, but moves the user's tongue 31 and soft palate 33 by changing the position of the head, so that the upper airway 37 can maintain a certain degree of smoothness.

The fifteenth figure is a first variation of the pillow body in the second embodiment of the angle positioning unit of the present invention, which comprises an internally deformable right side support structure 1402, a deformable left side support structure 1404 and a deformable shoulder support. The pillow body 140 of the structure 1406. Figure 16 is a second variation comprising a pillow body having a deformable right side support structure 1502, a deformable left side support structure 1504, a deformable neck support structure 1506 and a deformable shoulder support structure 1508. 150.

Figure 17 shows a second embodiment of the angular positioning unit of the present invention. The embodiment combines a respiratory state sensor 92 and a head position sensor 94 to facilitate a system for determining the head angle θhead and torso angle θtorso that the user is most suitable for negative pressure breathing therapy. The system mainly includes a pillow body 900, a breathing state sensor 92, a head position sensor 94 and a controller 96. The pillow body 900 is internally provided with a deformable right side support structure 902, a deformable left side support structure 904 and a deformable neck support structure 906. In an embodiment of the invention, the controller 96 has a gas pressure delivery unit (not shown), and the gas lines 960, 962, and 964 are respectively connected to the deformable right side support structure 902, and the deformable left side support The structure 904 and the deformable neck support structure 906 are configured such that the gas pressure delivery unit can deliver an appropriate amount of gas to the deformable right side support structure 902, the deformable left side support structure 904, and the deformable neck support structure as needed. Any of 906 adjusts the head angle θhead of the user to the torso angle θtorso. The respiratory state sensor 92 is configured to detect the breathing state of the user and transmit the detected respiratory state information to the controller 96 via an electrical connection line 966. The controller 96 controls the gas delivery path of the gas pressure delivery unit inside thereof according to the respiratory state information to deliver the gas to the deformable support structure of the gas to be filled, thereby adjusting the head, neck and shoulder of the user to The desired location.

In some embodiments of the present invention, the respiratory state sensor 92 may be a respiratory flu detector, a respiratory airflow pressure sensor, a microphone snoring sensor, a respiratory air temperature sensor (thermistor), or blood oxygenation. Oximeter. In one embodiment of the invention, the respiratory state sensor 92 is configured to detect a flow resistance of the user's respiratory airflow, and the respiratory flow resistance of the user is represented by a snoring map or a respiratory airflow pattern.

The head position sensor 94 is configured to detect the head position of the user on the pillow body 900 and transmit a head position signal to the controller 96 via an electrical connection line 968. In an embodiment of the invention, the head The position sensor 94 can be an accelerometer that is preferably placed over the user's forehead. In some embodiments of the invention, the head position sensor 94 can be a pressure sensor, a load cell, or a piezo sensor. In these embodiments, the head position sensor 94 can be placed in position on the user's head in different embodiments. In an embodiment of the invention, the controller 96 can determine the head, neck and shoulder positions of the user that are most suitable for negative pressure breathing therapy based on the received respiratory state information and the corresponding head position signal. In one embodiment of the invention, the optimal head, neck and shoulder positions correspond to a minimum respiratory flow resistance of the user.

It is worth noting that the change in the position of the user's head affects the neck and shoulder position of the user, so the optimal head position is used to represent the optimal head, neck and shoulder position.

Figure 18 is a flow chart showing the steps of determining the optimum head position of the user by the system of Fig. 17. The flow chart of the steps of the eighteenth embodiment will be described below in conjunction with the seventeenth embodiment. First, in step 1001, the user is placed in a supine position, at which time the user faces directly above the face of the pillow body 900 below his head. The respiratory state sensor 92 measures the flow resistance of the user's respiratory airflow, the measurement time lasts for one measurement period, such as ninety minutes, or lasts all night, and transmits the measured respiratory airflow resistance to the controller 96. In some embodiments of the invention, the measured respiratory airflow resistance is the user's snoring map or respiratory airflow pattern. In other embodiments of the invention, the invention may measure changes in the respiratory airflow pressure of the user, changes in respiratory airflow temperature, or oxygen levels in the blood. Next, in step 1002, the stretching angle of the user's neck reclining is sequentially increased from 0 degrees to 90 degrees, and the stretching angle can adjust the tension of the upper airway side wall muscle to reduce the collapse of the airway. In this step, the present invention delivers gas to the deformable neck through the gas pressure delivery unit of the controller 96. The support structure 906 is configured to sequentially increase the height of the deformable neck support structure 906 from 0 mm to 50 mm, thereby raising the shoulder of the user to gradually increase the extension angle of the neck. In the present invention, each head position of the user is defined as a sleep position. Next, in step 1003, the user's head position is maintained at each individual neck extension angle for about one measurement period and the user's respiratory airflow resistance is measured, while the head position sensor 94 will detect The user head position signal received is transmitted to the controller 96. In one embodiment of the invention, the measurement period can be ninety minutes, three to four hours, or one night. Steps 1002 through 1003 are repeated until the measurement of the respiratory airflow resistance at all individual neck extension angles of the user is completed. Next, in step 1004, the angle of the user's head to the right is sequentially increased from 0 degrees to 90 degrees. In this step, the present invention delivers gas to the deformable left side support structure 904 through the gas pressure delivery unit of the controller 96 to sequentially increase the angle of rotation of the user's head to the right. Then, returning to step 1003, the user's head position is maintained at each individual right-hand rotation angle for about one measurement period and the user's respiratory airflow resistance is measured, and the head position sensor 94 detects The user head position signal received is transmitted to the controller 96. Step 1004 and step 1003 are repeated until the measurement of the respiratory airflow resistance at the right angle of rotation of all of the individual heads of the user is completed. Then, step 1004 is further performed to sequentially increase the angle of the user's head to the left side from 0 degrees to 90 degrees. In this step, the present invention delivers gas to the deformable right side support structure 902 through the gas pressure delivery unit of the controller 96 to sequentially increase the angle of rotation of the user's head to the left side. Then, returning to step 1003, the user's head position is maintained at each individual left-hand rotation angle for about one measurement period and the user's respiratory airflow resistance is measured, and the head position sensor 94 detects The user head position signal received is transmitted to the controller 96. Repeat step 1004 and step 1003 until the flow of the respiratory airflow at the left angle of rotation of all the individual heads of the user is completed. measuring. Next, in step 1005, the present invention performs the measurement and analysis of the respiratory airflow resistance of all sleep positions (head positions) of the user through the controller 96. Finally, at step 1006, the controller 96 determines the optimal head position for the user to use the pillow 90 based on all sleep positions and corresponding respiratory airflow resistance. In an embodiment of the invention, the optimal head position is such that the user has a minimum respiratory airflow resistance when using the pillow body 900. When the user uses the pillow body 900, the present invention can set the optimal head position through the controller 96, and the controller 96 controls the gas pressure delivery unit to deliver an appropriate amount of gas according to the optimized head position. The deformable support structure is required until the pillow body 900 adjusts the user's head to the optimal head position to facilitate the patency of the upper airway when the user is supine.

In some embodiments of the invention, the present invention may perform a head position parameter measurement step to detect the position of the user's head. The head position parameter can be selected from any of the following: acceleration, pressure, load, and piezoelectric variation. In addition, in some embodiments of the present invention, the present invention may perform a breathing detection step to detect the breathing state of the user, such as detecting the user's respiratory airflow, respiratory airflow pressure, snoring, respiratory airflow temperature, and Any of the blood oxygen concentrations.

Another aspect of the present invention is to apply the concept of a head position adjustment mechanism to the concept of an oral negative pressure respiratory therapy mechanism to a system for improving upper patency of a user during sleep; wherein the head position adjustment mechanism of the present invention can be at the aforementioned angle Various embodiments of the positioning device and variations thereof are realized, and the aforementioned oral negative pressure respiratory therapy mechanism can be realized by various oral interface devices that generate a negative pressure environment in the user's mouth, for example, an application filed on January 10, 2014. Oral interface device of PCT International Patent Application No. PCT/US14/11129. Figure 19 is a combination of the aforementioned head position adjustment mechanism and oral negative pressure breathing therapy mechanism to improve the upper airway patency during sleep of the user. In a specific embodiment of the system, in this embodiment, the system combines the system of the seventeenth embodiment with a one-port interface unit 98. The mouth interface unit 98 has a gas flow conduit 980 connected to one end of a gas line 970, and a vacuum source 972 is connected to the other end of the gas line 970 and provides a negative pressure to the mouth through the gas line 970. Interface unit 98. In an embodiment of the invention, the present invention further includes a reservoir 97 disposed on the gas line 970 between the oral interface unit 98 and the vacuum source 972 to collect residual gas in the gas line 970. Liquid, such as the user's saliva, to facilitate the delivery of negative pressure. In this embodiment, the gas line 970 that communicates between the vacuum source 972 and the oral interface unit 98 constitutes a negative pressure path. In this embodiment, the present invention first determines, by the system of FIG. 17, the optimal head position of the user for performing negative pressure breathing therapy and adjusts the user's sleep posture to the optimal head position, and then transmits the vacuum source. The 972 and the oral interface unit 98 delivers a negative pressure to the user's mouth to create a sealed negative pressure environment in the oral cavity, thereby administering oral negative pressure breathing therapy to the user. In an embodiment of the invention, the user's oral negative pressure value is -20 mmHg to -60 mmHg.

FIG. 20 is another embodiment of the system for combining the head position adjustment mechanism and the oral negative pressure breathing therapy mechanism to improve the upper airway patency of the user during sleep, the system integrating the oral interface unit 98 The system to the seventeenth figure. The twenty-first figure is a schematic diagram of a user performing sleep negative pressure breathing therapy using the system of the twentieth embodiment of the present invention. In an embodiment of the invention, the controller 96 is internally provided with a microprocessor 9601 and a pumping pump 9602. The inlet end of the pumping pump 9602 is connected to the gas line 970 to transmit the negative pressure. To the user's mouth. In this embodiment, the gas line 970 that communicates between the pumping pump 9602 and the oral interface unit 98 constitutes a negative pressure path. Further, a pressure sensor 9605 is connected to the gas line 970 to detect a negative pressure value transmitted to the oral cavity of the user. In the embodiment, the negative pressure value is -20 mmHg to -60 mmHg. Additionally, the reservoir 97 is disposed on the gas line 970 for collecting liquid residues remaining in the gas line 970, such as saliva of the user, to maintain the flow of the negative pressure path. The pressure value detected by the pressure sensor 9605 can also be used to determine whether the negative pressure path is blocked. For example, when the pressure value detected by the pressure sensor 9605 cannot be lowered, it can be used as a warning that the negative pressure path encounters a liquid blockage. An outlet end of the pumping pump 9602 is connected to the deformable right side support structure 902, the deformable left side support structure 904 and the deformable neck support of the pillow body 900 through the gas lines 960, 962, and 964, respectively. Structure 906 to deliver a suitable amount of gas to the deformable right side support structure 902, the deformable left side support structure 904, and the deformable neck support structure 906, thereby adjusting the user's head, neck and shoulders position. In an embodiment of the invention, the controller 96 further includes a gas pressure delivery selector 9604 that communicates with the gas lines 960, 962, 964, and the microprocessor 9601 can control the gas pressure delivery selector 9604 to determine A gas delivery path between the controller 96 and the pillow body 900. In an embodiment of the invention, the present invention further includes a first switching control valve 9603 disposed between the pumping pump 9602 and the gas pressure delivery selector 9604 and a second switching control valve 9607 disposed on the pumping The gas pump 9662 is between the gas line 970 and the gas line 960. The microprocessor 9601 can control the first switching control valve 9603 and the second switching control valve 9607 to change the airflow direction of the pumping pump 9602, such as the twenty-third, twenty-fourth, or twenty-fifth The figure shows. In an embodiment of the invention, the present invention further includes a check valve 9606 disposed on the gas line 970 to control the negative pressure transfer direction of the system of the present invention from the inlet end of the pumping pump 9602 to the The airflow conduit 980 of the oral interface device 98.

Figure 22 is a flow chart showing the steps of optimizing the head position adjustment and the negative pressure breathing treatment for the user using the twentieth system of the present invention. The user can perform negative pressure breathing therapy in a sleeping posture that optimizes the head position, thereby providing a safer and more comfortable sleep quality for the user. First, in step 1901, the user is found to optimize the head position (see FIG. 18), and the information of the optimized head position is set inside the microprocessor 9601. In this step, the microprocessor 9601 controls the first switching control valve 9603 and the second switching control valve 9607 to change the airflow direction of the system of the present invention as shown in the twenty-third figure, and the airflow direction is ambient air from an airflow. The passage 992 enters, passes through the second switching control valve 9607, enters the inlet end of the pumping pump 9602, and is then sent from the outlet end of the pumping pump 9602 to the gas pressure delivery selector 9604, and in the micro processing Gas is delivered to one of the gas lines 960, 962, 964 under the control of the device 9601. In step 1901, the present invention sets the airflow direction of the system to the airflow direction shown in the twenty-third figure while performing the step flow chart of the eighteenth figure to find the optimal head position of the user, and the optimum The information of the position of the head is set inside the microprocessor 9601. At step 1902, the present invention detects the position of the user's head through the head position sensor 94. Next, in step 1903, the system of the present invention applies negative pressure breathing therapy to the user and performs head position adjustment and detection based on the detected head position information. The microprocessor 9601 determines a path for the gas to be deformed into the support structure of the pillow body 900 based on the detected head position information. In this step, the microprocessor 9601 controls the first switching control valve 9603 and the second switching control valve 9607 to change the airflow direction of the system of the present invention as shown in the twenty-fourth figure, so that the airflow direction is the pumping gang. The Pu 9602 transmits a negative pressure to the inside of the user's mouth through its inlet end, and delivers gas through its outlet end to a deformable support structure inside the pillow body 900 that needs to be filled with gas to adjust the position of the user's head. The head position sensor 94 synchronously detects the position of the user's head and transmits a message detecting the position of the head to the microprocessor 9601. The microprocessor 9601 is further configured according to the detected head position information The user optimizes the difference in head position setting values to change the gas delivery path of the gas pressure delivery selector 9604 and continues to adjust the user's head position. Repeat steps 1902 and 1903 until the system of the present invention detects that the user has been adjusted to the optimal head position. At this time, the microprocessor 9601 controls the first switching control valve 9603 and the second switching control. The valve 9607 changes the flow direction of the system of the present invention as shown in the twenty-fifth diagram, and the gas of the pumping pump 9602 is transferred to the external environment through the first switching control valve 9603 and an air flow passage 990, the system of the present invention That is, the gas to the deformable support structure inside the pillow body 900 is stopped, but at this stage, since the deformable support structure and the gas pressure transport selector 9604 form a gas-tight passage, the pillow body 900 remains The deformation state that maintains the user's optimal head position is maintained, and the system of the present invention maintains the delivery of negative pressure to the interior of the user's mouth.

In this way, the present invention can enable the user to perform effective negative pressure breathing therapy while maintaining the optimal sleep posture during sleep through the system of the nineteenth or the twentieth.

Next, please refer to the twenty-sixth to twenty-ninth figures, which show various variations of the specific embodiment shown in the twentieth embodiment. The variation of the twenty-sixth to twenty-ninth figures mainly shows the coupling relationship between the pillow body and the controller 96, and the breathing state sensor 92 and the head position sensor 94 are based on the controller The combination of 96 and their functions are the same as those of the twentieth embodiment, and are omitted from some of the drawings of the twenty-sixth to twenty-ninthth drawings.

A variation of the twenty-sixth embodiment includes a pillow body 110 having a deformable neck/shoulder support bladder 1102 disposed therein that communicates with the controller 96 through a gas line 122. In this variation, see FIG. 26B and FIG. 26C, the present invention changes the deformable neck/shoulder support airbag 1102 by introducing a gas into the deformable neck/shoulder support airbag 1102. The height, in turn, changes the neck extension angle of the user to adjust the position of the user's head, neck and shoulders to facilitate improved upper airway patency of the user. A variation of the twenty-seventh embodiment includes a pillow body 110 having a deformable left side support air bag 1104 disposed therein that communicates with the controller 96 through a gas line 122. In this variation, please refer to the twenty-seventh B and twenty-seventh C. The present invention rotates the user's head to the right by passing a gas to the left support airbag 1104 to adjust the user. Head, neck and shoulder position to facilitate improved upper airway patency of the user. A variation of the twenty-eighth A diagram includes a pillow body 110 having a deformable head support balloon 1100 disposed therein that communicates with the controller 96 through a gas line 122. In this variation, see FIG. 28B, the present invention changes the height of the deformable head support balloon 1100 by introducing a gas into the deformable head support balloon 1100, thereby changing the neck extension of the user. The angle is adjusted to adjust the position of the head, neck and shoulder of the user to improve the upper airway patency of the user. The variation of the twenty-ninth embodiment includes a pillow body 110. The pillow body 110 is internally provided with a deformable head support air bag 1100 and a deformable left side support air bag 1104, which are respectively communicated with the gas line 122b through the gas line 122a. The controller 96.

The above description is only for the specific embodiments of the present invention, and is not intended to limit the scope of the claims of the present invention; all other equivalent changes or modifications which are not departing from the spirit of the present invention should be included in the following Within the scope of the patent application.

92‧‧‧Respiratory sensor

94‧‧‧ head position sensor

96‧‧‧ Controller

97‧‧‧ liquid storage tank

98‧‧‧Mouth interface unit

900‧‧‧Pillow body

902‧‧‧ Deformable right side support structure

904‧‧‧ Deformable left support structure

906‧‧‧ deformable neck support structure

960, 962, 964‧‧‧ gas pipeline

966, 968‧‧‧ electrical connection lines

970‧‧‧ gas pipeline

980‧‧‧ gas conduit

Claims (15)

A system for improving patency of upper airway, comprising: an angle positioning unit for adjusting a relative angle range of a head, a neck and a shoulder when a user sleeps, which is most suitable for negative pressure breathing therapy, wherein the most suitable for negative pressure breathing The relative angle of treatment includes the angle of the head and the angle of the torso, which is defined as the angle between the centerline of the neck and the line connecting the highest point of the nose and the nose. The angle of the torso is defined as the angle between the centerline of the neck and the centerline of the trunk. An oral interface unit that delivers negative pressure pressure to the oral cavity; and a vacuum source that provides negative pressure to the oral interface unit. The system for improving upper airway patency as described in claim 1, further comprising a controller for controlling the angular positioning unit and the vacuum source. A system for improving upper airway patency as described in claim 2, wherein the controller includes a gas pressure delivery unit that provides positive pressure to the angular positioning unit to adjust the user's head, neck and shoulders. At least one location of the location. The system for improving upper airway patency as described in claim 2, wherein the controller comprises a gas pressure delivery unit, which can provide a negative pressure to the angle positioning unit to adjust the head and neck of the user. At least one location of the shoulder position. A system for improving upper airway patency according to any one of claims 3 or 4, wherein the gas pressure delivery unit comprises a gas pressure delivery selector for controlling a positive pressure transmission path of the gas pressure delivery unit. . The system for improving upper airway patency as described in claim 1, wherein the angle positioning unit comprises at least one deformable support structure selected from the group consisting of a head support structure, a left support structure, and a right side support. Structure, neck support structure, shoulder support structure, neck/shoulder support structure and its group Hehe. The system for improving upper airway patency as described in claim 6, wherein the deformable support structure further comprises a pore structure selected from the group consisting of: an expandable polymer structure, A foam structure, a porous latex structure, a porous silicone structure, a natural fiber structure, a rayon structure, or a combination of the above. The system for improving the patency of the upper respiratory tract as described in claim 2, further comprising a head position sensor for detecting the position of the head of the user and transmitting a head position signal thereto The controller. The system for improving upper airway patency as described in claim 1 further includes a respiratory state sensor for detecting a breathing state of the user. The system for improving the patency of the upper airway according to the first aspect of the patent application, wherein the oral interface unit transmits a negative pressure to the oral cavity, and generates a sealed negative pressure environment in the user's mouth, using a negative pressure The tongue and soft palate move forward and upward to the mouth to increase the distance between the soft palate and the base of the tongue and the back wall of the throat to improve the upper airway patency of the user. The system for improving upper patency of the upper airway according to claim 1, further comprising a negative pressure passage formed between the vacuum source and the oral interface unit to collect the user Saliva. A system for improving upper airway patency as described in claim 1, wherein the negative pressure value in the oral cavity of the user is -20 mmHg to -60 mmHg. A system for improving upper airway patency as described in claim 1, wherein the head angle is in the range of -40 to 10 degrees in the relative angle most suitable for negative pressure breathing therapy. Improve upper tract patency as described in item 1 of the patent application The system wherein the relative angle of the most suitable negative pressure breathing therapy ranges from -10 degrees to 30 degrees. The system for improving upper airway patency as described in claim 1, wherein the angle positioning unit controls the user's head to turn right 30 to 60 degrees or left to 30 degrees to 60 degrees.