TWI558435B - Neutron capture therapy, and neutron capture therapy systems - Google Patents
Neutron capture therapy, and neutron capture therapy systems Download PDFInfo
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本申請主張基於2014年10月27日申請之日本專利申請第2014-218565號之優先權。該日本申請之全部內容藉由參閱援用於本說明書中。 The present application claims priority based on Japanese Patent Application No. 2014-218565, filed on Oct. 27, 2014. The entire contents of this Japanese application are incorporated herein by reference.
本發明係關於中子捕獲治療用治療台及中子捕獲治療系統。 The present invention relates to a treatment table for neutron capture therapy and a neutron capture therapy system.
在專利文獻1揭示一種治療台,用於藉由照射中子束來對患者(被照射體)進行治療之中子捕獲治療時。該治療台具備基座部、載置患者之頂板(載置部)、及安裝有對照射於患者之中子束的照射範圍進行規定之準直器的準直器安裝部。頂板能夠相對於基座部移動,準直器安裝部固定於基座部。該治療台中,藉由使頂板相對於基座部移動,能夠調整頂板與準直器之間的位置關係。 Patent Document 1 discloses a treatment table for performing a therapeutic neutron capture treatment on a patient (irradiated body) by irradiating a neutron beam. The treatment table includes a base portion, a top plate (mounting portion) on which the patient is placed, and a collimator mounting portion to which a collimator that defines an irradiation range of the sub-beams irradiated to the patient is attached. The top plate is movable relative to the base portion, and the collimator mounting portion is fixed to the base portion. In the treatment table, the positional relationship between the top plate and the collimator can be adjusted by moving the top plate relative to the base portion.
在專利文獻1中所記載之中子捕獲治療系統,首先,在準備室束縛躺臥在頂板上之患者,並且使頂板相對於基座部移動,將患者的照射目標與準直器進行對準。當對準之後,從準備室將治療台移動到照射室。照射室中,在設 置於照射室內的壁部之中子束的照射口嵌入準直器,進行中子束的照射。移動治療台時,因為準備室的門、照射室的門或照射室與準備室之間的通道的寬度較窄,為了抑制在移動時頂板與該等門互相干擾,相對於基座部旋轉頂板而在使頂板的長邊方向沿著治療台的移動方向的狀態下移動治療台,移動結束之後,旋轉頂板使其恢復到與對準時相同的方向。 In the neutron capture treatment system described in Patent Document 1, first, the patient lying on the top plate is restrained in the preparation chamber, and the top plate is moved relative to the base portion to align the patient's irradiation target with the collimator. . After alignment, the treatment table is moved from the preparation chamber to the illumination chamber. In the irradiation room, in the setting The irradiation port of the beamlets placed in the wall portion of the irradiation chamber is inserted into the collimator to irradiate the neutron beam. When the treatment table is moved, since the width of the passage between the door of the preparation chamber, the door of the irradiation chamber, or the irradiation chamber and the preparation chamber is narrow, in order to suppress mutual interference between the top plate and the doors when moving, the top plate is rotated relative to the base portion. On the other hand, the treatment table is moved in a state in which the longitudinal direction of the top plate is moved along the moving direction of the treatment table, and after the end of the movement, the top plate is rotated to return to the same direction as the alignment.
如前述般不在照射室而在準備室進行患者與準直器之間的對準之原因如下。亦即,在中子捕獲治療,雖較佳為對患者精確地照射中子束,但實際上可會對照射室內整體照射某種程度的中子束。因此,可能因照射室內的劑量變高,而不宜使作業人員或醫生在照射室內久留。另一方面,將載置於治療台之頂板上的患者與準直器進行對準需要花費一些時間。基於以上理由,不在照射室而在準備室對患者與準直器進行對準。 The reason for the alignment between the patient and the collimator in the preparation chamber without the irradiation chamber as described above is as follows. That is, in neutron capture therapy, it is preferred to accurately illuminate the neutron beam to the patient, but in practice, a certain degree of neutron beam may be irradiated to the entire irradiation chamber. Therefore, it may be that the dose in the irradiation room becomes high, and it is not suitable for the operator or the doctor to stay in the irradiation room for a long time. On the other hand, it takes some time to align the patient placed on the top plate of the treatment table with the collimator. For the above reasons, the patient and the collimator are aligned in the preparation chamber without the irradiation chamber.
如前述般準備室的門和照射室的門的寬度較窄之原因如下。亦即,準備室的門和照射室的門通常由屏蔽放射線之鉛等屏蔽體構成,且形成為非常厚。開閉門時例如使用馬達等,因為門的重量較大,基於安全性觀點考慮需要以低速進行開閉。因此門越寬,開閉時所需的時間越長。基於以上原因,準備室的門和照射室的門的寬度較窄。另外,在門的寬度較大的情況,可能將讓治療台通過時因門打開所形成之開口的寬度縮窄,從而減少門的移動量。 The reason why the width of the door of the preparation room and the door of the irradiation room is narrow as described above is as follows. That is, the door of the preparation room and the door of the irradiation room are usually made of a shield such as lead shielding radiation, and are formed to be very thick. For example, a motor or the like is used when opening and closing the door, and since the weight of the door is large, it is necessary to open and close at a low speed from the viewpoint of safety. Therefore, the wider the door, the longer it takes to open and close. For the above reasons, the width of the door of the preparation room and the door of the irradiation room is narrow. In addition, in the case where the width of the door is large, the width of the opening formed by the opening of the door when the treatment table is passed may be narrowed, thereby reducing the amount of movement of the door.
專利文獻1:日本特開2014-161621號公報 Patent Document 1: Japanese Laid-Open Patent Publication No. 2014-161621
在上述專利文獻1所記載之中子捕獲治療系統,因為如前述般準直器安裝部固定於基座部,若在移動治療台時使頂板相對於基座部旋轉,則頂板與準直器之間的位置關係將發生變化。因此,移動結束之後,即便旋轉頂板使其方向與設置時的方向相同而重現準備室內的狀態,仍有可能無法使頂板準確返回到原來的位置。此時,有可能導致準直器與患者之間的位置關係偏離設置時的位置關係,而無法按計劃進行治療。 In the neutron capture treatment system described in Patent Document 1, since the collimator attachment portion is fixed to the base portion as described above, if the top plate is rotated relative to the base portion when the treatment table is moved, the top plate and the collimator The positional relationship between them will change. Therefore, after the end of the movement, even if the top plate is rotated so that the direction is the same as that in the setting, and the state in the preparation room is reproduced, the top plate may not be accurately returned to the original position. At this time, there is a possibility that the positional relationship between the collimator and the patient deviates from the positional relationship at the time of setting, and the treatment cannot be planned as planned.
本發明係鑑於上述情況而完成者,其目的在於提供一種能夠保持準直器與被照射體的位置關係並將中子捕獲治療用治療台移動到照射室之中子捕獲治療用治療台及中子捕獲治療系統。 The present invention has been made in view of the above circumstances, and an object thereof is to provide a treatment table for a sub-capture treatment that can maintain a positional relationship between a collimator and an object to be irradiated and move the neutron capture treatment treatment table into the irradiation room. Sub-capture treatment system.
本發明之中子捕獲治療用治療台,係在進行將中子束照射於被照射體的中子捕獲治療時用於載置被照射體,其具備:行走部,沿地面行走;頂板,設置於行走部上,且用於載置被照射體;準直器,設置於行走部上,且設有用 於規定中子束的照射範圍之開口;準直器安裝部,以能夠調整準直器相對於頂板的位置之方式支撐準直器;及第1旋轉支撐部,以能夠相對於行走部一起旋轉的方式支撐頂板及準直器。 The treatment table for neutron capture treatment of the present invention is for placing an object to be irradiated when performing neutron capture treatment for irradiating a neutron beam to an object to be irradiated, comprising: a walking portion, walking along the ground; and a top plate On the walking portion, and for placing the object to be irradiated; the collimator is disposed on the running portion and is provided for use An opening for defining an irradiation range of the neutron beam; the collimator mounting portion supports the collimator so as to adjust a position of the collimator relative to the top plate; and the first rotation support portion to be rotatable relative to the running portion The way to support the top plate and collimator.
本發明中,進行設置時,藉由準直器安裝部來調整準直器相對於頂板(被照射體)的位置關係,而將頂板與準直器進行對準。此外,移動治療台時,藉由旋轉第1旋轉支撐部,使頂板及準直器一起相對於行走部旋轉,以實現不使頂板與準備室的門等互相干擾的狀態。此時,由於頂板與準直器一體地旋轉,頂板與準直器之間的位置關係不發生變化。而且,移動結束之後,藉由使第1旋轉支撐部旋轉至設置時的位置,能夠準確重現設置時的狀態。因此,依據本發明,能夠保持準直器與被照射體的位置關係並將治療台移動到照射室。 In the present invention, when the setting is performed, the positional relationship of the collimator with respect to the top plate (irradiated body) is adjusted by the collimator mounting portion, and the top plate and the collimator are aligned. Further, when the treatment table is moved, the top plate and the collimator are rotated together with respect to the traveling portion by rotating the first rotation support portion, thereby achieving a state in which the top plate and the door of the preparation room do not interfere with each other. At this time, since the top plate and the collimator are integrally rotated, the positional relationship between the top plate and the collimator does not change. Further, after the end of the movement, by rotating the first rotation support portion to the position at the time of installation, it is possible to accurately reproduce the state at the time of installation. Therefore, according to the present invention, the positional relationship between the collimator and the irradiated body can be maintained and the treatment table can be moved to the irradiation chamber.
此外,在本發明之中子捕獲治療用治療台,準直器安裝部可以具有:以能夠相對於頂板旋轉的方式支撐準直器之第2旋轉支撐部。依據該構造,能夠以簡單的構造藉由準直器安裝部調整準直器相對於頂板的位置。 Further, in the neutron capture treatment treatment table of the present invention, the collimator attachment portion may have a second rotation support portion that supports the collimator so as to be rotatable relative to the top plate. According to this configuration, the position of the collimator with respect to the top plate can be adjusted by the collimator mounting portion with a simple configuration.
此外,在本發明之中子捕獲治療用治療台,第1旋轉支撐部的旋轉軸與第2旋轉支撐部的旋轉軸可以位於同一直線上。在中子捕獲治療系統,可能在設置於照射室內的壁部之中子束的照射口嵌入準直器。此時,在進行設置時,藉由旋轉第2旋轉支撐部將頂板與準直器進行對準,並且藉由旋轉第1旋轉支撐部進行準直器對於照射口的定 位。此時,為了將準直器嵌入於照射口,需要將準直器的位置及姿勢均對準照射口。假使第1旋轉支撐部的旋轉軸與第2旋轉支撐部的旋轉軸不同時,第1旋轉支撐部旋轉時與第2旋轉支撐部旋轉時之準直器的移動軌道不同,因此難以將準直器的位置及姿勢均對準到照射口。在這一點上,依據該構造,第1旋轉支撐部的旋轉軸與第2旋轉支撐部的旋轉軸位於同一直線上,不論是讓第1旋轉支撐部及第2旋轉支撐部之哪個旋轉,準直器都在同一個圓周上移動,因此能夠輕鬆地將準直器的位置及姿勢對準到照射口。 Further, in the neutron capture treatment treatment table of the present invention, the rotation axis of the first rotation support portion and the rotation axis of the second rotation support portion may be on the same straight line. In the neutron capture treatment system, it is possible to embed the collimator in the illumination port of the beamlets disposed in the wall portion of the irradiation chamber. At this time, when the setting is performed, the top plate and the collimator are aligned by rotating the second rotation support portion, and the alignment of the collimator with respect to the irradiation port is performed by rotating the first rotation support portion. Bit. At this time, in order to embed the collimator in the irradiation port, it is necessary to align the position and posture of the collimator with the irradiation port. When the rotation axis of the first rotation support portion is different from the rotation axis of the second rotation support portion, the movement of the first rotation support portion is different from that of the collimator when the second rotation support portion is rotated, so that it is difficult to collimate The position and posture of the device are aligned to the illumination port. In this regard, according to this configuration, the rotation axis of the first rotation support portion and the rotation axis of the second rotation support portion are on the same straight line, and regardless of which of the first rotation support portion and the second rotation support portion is rotated, The straighteners move on the same circumference, so it is easy to align the position and posture of the collimator to the illumination port.
此外,在本發明之中子捕獲治療用治療台,行走部可以具有:沿著地面移動之基底部、及使第1旋轉支撐部相對於基底部朝向與基底部的移動方向交叉的方向移動之橫移部。在中子捕獲治療系統,可能將中子束的照射口設置成,在與行走部(基底部)的移動方向交叉的方向開口。在這一點上,依據該構造,將準直器設置於既定位置之後,藉由橫移部朝向該方向使第1旋轉支撐部(頂板及準直器)移動,從而能夠將準直器嵌入於照射口。因此,相較於例如由作業人員等移動能夠在地面上朝向任意方向移動之治療台來將準直器嵌入於照射口的情況,能夠輕鬆準確地將準直器嵌入於照射口。 Further, in the treatment table for neutron capture treatment of the present invention, the traveling portion may have a base portion that moves along the ground and a direction in which the first rotation support portion is moved in a direction intersecting the movement direction of the base portion with respect to the base portion. Traverse section. In the neutron capture treatment system, it is possible to set the irradiation port of the neutron beam to open in a direction crossing the moving direction of the running portion (base portion). In this regard, according to this configuration, after the collimator is placed at the predetermined position, the first rotation support portion (the top plate and the collimator) is moved in the direction by the traverse portion, so that the collimator can be embedded in Irradiation port. Therefore, the collimator can be easily and accurately inserted into the irradiation port as compared with a case where the collimator can be inserted into the irradiation port by, for example, a treatment table that can be moved in an arbitrary direction on the ground by an operator or the like.
此外,在本發明之中子捕獲治療系統,係將中子束照射於被照射體,其具備:申請專利範圍第1~4項中任一項所述之中子捕獲治療用治療台;進行準直器與被照射體 的位置關係的調整之準備室;朝向被照射體進行中子束的照射之照射室;及設置於照射室內的壁部之中子束的照射口,中子捕獲治療用治療台能夠在準備室與照射室之間行走。 Further, in the neutron capture and treatment system of the present invention, the neutron beam is irradiated onto the object to be irradiated, and the treatment table for neutron capture treatment according to any one of claims 1 to 4 is provided; Collimator and irradiated body a preparation room for adjusting the positional relationship; an irradiation chamber for irradiating the neutron beam toward the irradiated body; and an irradiation port for the sub-beams provided in the wall portion of the irradiation chamber, and the treatment table for the neutron capture treatment can be in the preparation room Walk with the irradiation room.
本發明中,進行設置時,藉由準直器安裝部調整準直器相對於頂板(被照射體)的位置關係,而將頂板與準直器進行對準。此外,移動治療台時,藉由旋轉第1旋轉支撐部,使頂板及準直器一起相對於行走部旋轉,以實現不使頂板與準備室的門等互相干擾的狀態。此時,由於頂板與準直器一體地旋轉,頂板與準直器之間的位置關係不發生變化。而且,移動結束之後,藉由使第1旋轉支撐部旋轉至設置時的位置,能夠準確重現設置時的狀態。因此,依據本發明,能夠保持準直器與被照射體的位置關係並將治療台移動到照射室。 In the present invention, when the setting is performed, the positional relationship of the collimator with respect to the top plate (irradiated body) is adjusted by the collimator mounting portion, and the top plate and the collimator are aligned. Further, when the treatment table is moved, the top plate and the collimator are rotated together with respect to the traveling portion by rotating the first rotation support portion, thereby achieving a state in which the top plate and the door of the preparation room do not interfere with each other. At this time, since the top plate and the collimator are integrally rotated, the positional relationship between the top plate and the collimator does not change. Further, after the end of the movement, by rotating the first rotation support portion to the position at the time of installation, it is possible to accurately reproduce the state at the time of installation. Therefore, according to the present invention, the positional relationship between the collimator and the irradiated body can be maintained and the treatment table can be moved to the irradiation chamber.
此外,在本發明之中子捕獲治療系統,可以在照射室與準備室之間設置有:屏蔽從照射室的內部放射的放射線之門,讓中子捕獲治療用治療台通過時因門打開所形成之開口的寬度,是比頂板的長邊方向的長度更小。依據該中子捕獲治療系統,即便在讓中子捕獲治療用治療台通過時因門打開所形成之開口的寬度比頂板的長邊方向的長度更小的情況,亦能夠保持準直器與被照射體的位置關係並將治療台移動到照射室。 Further, in the neutron capture treatment system of the present invention, a door for shielding radiation emitted from the inside of the irradiation chamber may be provided between the irradiation chamber and the preparation chamber, so that the neutron capture treatment treatment table passes through the door opening The width of the formed opening is smaller than the length of the top side of the top plate. According to the neutron capture treatment system, even when the neutron capture treatment treatment table is passed, the width of the opening formed by the opening of the door is smaller than the length of the longitudinal direction of the top plate, and the collimator and the keeper can be maintained. The positional relationship of the illuminating body and the treatment table are moved to the irradiation room.
依據本發明,提供一種能夠保持準直器與被照射體的位置關係並將中子捕獲治療用治療台移動到照射室之中子捕獲治療用治療台及中子捕獲治療系統。 According to the present invention, there is provided a sub-capture treatment treatment table and a neutron capture treatment system capable of maintaining a positional relationship between a collimator and an object to be irradiated and moving the neutron capture treatment treatment table into the irradiation room.
1‧‧‧中子捕獲治療系統 1‧‧‧neutron capture therapy system
2‧‧‧治療台(中子捕獲治療用治療台) 2‧‧‧ treatment table (treatment table for neutron capture therapy)
3‧‧‧準備室 3‧‧‧ preparation room
4‧‧‧照射室 4‧‧‧Induction room
14‧‧‧準直器 14‧‧‧ collimator
14a‧‧‧準直器的開口 14a‧‧ ‧ opening of the collimator
16‧‧‧照射口 16‧‧‧ illuminated mouth
30‧‧‧行走部 30‧‧‧ Walking Department
31‧‧‧基底部 31‧‧‧ base
33‧‧‧橫移部 33‧‧‧ traverse
41‧‧‧頂板 41‧‧‧ top board
47‧‧‧第1旋轉支撐機構(第1旋轉支撐部) 47‧‧‧1st rotation support mechanism (1st rotation support part)
50‧‧‧準直器安裝部 50‧‧‧collimator installation
55‧‧‧第2旋轉支撐機構(第2旋轉支撐部) 55‧‧‧2nd rotation support mechanism (2nd rotation support part)
A‧‧‧旋轉軸 A‧‧‧Rotary axis
D‧‧‧門 D‧‧‧ Door
L‧‧‧頂板的長邊方向的長度 L‧‧‧ Length of the long side of the top plate
M1‧‧‧由門所形成之開口 M1‧‧‧ openings formed by the door
N‧‧‧中子束 N‧‧‧neutron beam
S‧‧‧患者(被照射體) S‧‧‧ patients (irradiated body)
WD1‧‧‧由門所形成之開口的寬度 WD1‧‧‧The width of the opening formed by the door
第1圖係顯示實施形態的中子捕獲治療系統的構造及配置的示意圖。 Fig. 1 is a schematic view showing the structure and arrangement of a neutron capture treatment system according to an embodiment.
第2圖係顯示中子束生成部及其周圍的圖。 Fig. 2 is a view showing a neutron beam generating unit and its surroundings.
第3圖係顯示治療台的圖。 Figure 3 is a diagram showing the treatment table.
第4(a)~(c)圖係顯示治療台的移動的概略俯視圖。 The fourth (a) to (c) diagrams show a schematic plan view of the movement of the treatment table.
第5(a)~(c)圖係顯示治療台的移動的概略俯視圖,且係第4圖的後續圖。 The fifth (a) to (c) are schematic plan views showing the movement of the treatment table, and are subsequent views of Fig. 4.
以下,參閱附圖對本發明之較佳實施形態進行詳細說明。另外,各圖中對相同部分或相對應的部分標註相同的符號,並省略重複說明。此外,設定一XYZ軸坐標系(參考第2圖~第4圖),其將從後述中子束生成部9射出之中子束N的射出方向設為X軸,將與X軸正交且沿著地面F的方向設為Y軸,將與地面F垂直的方向設為Z軸,並將該坐標系適當地用於各構成要件的位置關係的說明中。 DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. In the drawings, the same reference numerals are given to the same or corresponding parts, and the repeated description is omitted. Further, an XYZ-axis coordinate system (refer to FIGS. 2 to 4) is set, and an emission direction in which the beamlet N is emitted from a neutron beam generation unit 9 to be described later is defined as an X-axis, and is orthogonal to the X-axis. The direction along the ground F is set to the Y axis, and the direction perpendicular to the floor F is set to the Z axis, and this coordinate system is appropriately used for the description of the positional relationship of each constituent element.
第1圖係顯示實施形態的中子捕獲治療系統的構造之 立體圖,第2圖係顯示中子束生成部及其周圍之圖。實施形態的中子捕獲治療系統1為進行硼中子捕獲治療(BNCT:Boron Neutorn Capture Therapy)的裝置。硼中子捕獲治療為藉由對注射硼(10B)的患者(被照射體)照射中子束來進行癌症治療之治療法。 Fig. 1 is a perspective view showing a structure of a neutron capture treatment system according to an embodiment, and Fig. 2 is a view showing a neutron beam generation unit and its surroundings. The neutron capture treatment system 1 of the embodiment is a device for performing boron neutron capture treatment (BNCT: Boron Neutorn Capture Therapy). By boron neutron capture therapy of a patient (to be irradiated) injection of boron neutron irradiation beam (10 B) to the cancer treatment therapy.
如第1圖所示,中子捕獲治療系統1具備:束縛患者並用於搬送、治療患者時之治療台2(中子捕獲治療用治療台)、實施將患者束縛在治療台2等的準備作業之準備室3、朝向患者照射中子束之照射室4、設置於準備室3與照射室4之間的聯絡室5、及與照射室4相鄰而設的中子束生成室6。在中子束生成室6內設置有產生中子束之中子束產生部7(第2圖)。 As shown in Fig. 1, the neutron capture treatment system 1 includes a treatment table 2 (a treatment table for neutron capture therapy) for binding and administering a patient, and a preparation for binding the patient to the treatment table 2, etc. The preparation chamber 3, the irradiation chamber 4 that irradiates the patient with the neutron beam, the communication chamber 5 provided between the preparation chamber 3 and the irradiation chamber 4, and the neutron beam generation chamber 6 provided adjacent to the irradiation chamber 4. The neutron beam generation sub-beam generation unit 7 (second diagram) is provided in the neutron beam generation chamber 6.
如第2圖所示,中子束產生部7具有:將帶電粒子加速以射出帶電粒子束P之加速器8、及從加速器8所射出之帶電粒子束P生成中子束N之中子束生成部9。加速器8例如為迴旋加速器,將帶電粒子加速並射出帶電粒子束P(例如質子束)。 As shown in Fig. 2, the neutron beam generating unit 7 includes an accelerator 8 that accelerates the charged particles to emit the charged particle beam P, and a charged particle beam P emitted from the accelerator 8 to generate a beamlet generation among the neutron beam N. Department 9. The accelerator 8 is, for example, a cyclotron that accelerates charged particles and emits a charged particle beam P (for example, a proton beam).
中子束生成部9包含:帶電粒子束掃描部11、用於產生中子束N之靶T、用於使中子束N減速以降低中子束N的能量之減速材料12、及屏蔽放射線之屏蔽體13。帶電粒子束掃描部11掃描帶電粒子束P,進行對靶T照射帶電粒子束P之照射控制。靶T例如能夠形成為由鈹(Be)構成的圓板形狀,但亦能夠採用其他形狀或液態者。靶T受到帶電粒子束P的照射之後產生中子束N。 The neutron beam generating unit 9 includes a charged particle beam scanning unit 11, a target T for generating the neutron beam N, a decelerating material 12 for decelerating the neutron beam N to reduce the energy of the neutron beam N, and shielding radiation. The shield 13 is provided. The charged particle beam scanning unit 11 scans the charged particle beam P to perform irradiation control for irradiating the target T with the charged particle beam P. The target T can be formed, for example, in the shape of a disk made of beryllium (Be), but other shapes or liquids can be used. The target T is irradiated with the charged particle beam P to generate a neutron beam N.
減速材料12及屏蔽體13的一部分設置於屏蔽照射室4與中子束生成室6之間的混凝土製屏蔽壁W內。減速材料12使從靶T射出之中子束N減速以降低中子束N的能量。減速材料12例如成為層疊不同的多種材料之層疊結構。屏蔽體13屏蔽不用於治療之中子束N、隨著靶T中的該中子束N的產生而產生的γ射線等二次放射線、及隨著減速材料12中的中子束N的減速而產生的γ射線等二次放射線,防止其等放射到外部(照射室4側)。 A part of the decelerating material 12 and the shield 13 is provided in the concrete shield wall W between the shield irradiation chamber 4 and the neutron beam generating chamber 6. The decelerating material 12 decelerates the sub-beam N emitted from the target T to reduce the energy of the neutron beam N. The decelerating material 12 is, for example, a laminated structure in which a plurality of different materials are laminated. The shield 13 shields secondary radiation such as gamma rays generated by the generation of the neutron beam N, the generation of the neutron beam N in the target T, and the deceleration of the neutron beam N in the decelerating material 12. The secondary radiation such as γ-rays generated is prevented from being radiated to the outside (on the side of the irradiation chamber 4).
在減速材料12之前方配置有用於規定中子束N照射患者S的照射範圍的準直器14。中子束生成部9中,帶電粒子束P照射靶T,藉此產生中子束N。所產生之中子束N藉由減速材料12進行減速。從減速材料12射出之中子束N通過準直器14之後照射於治療台2上的患者S。中子束N包括高速中子束、超熱中子束及熱中子束,還伴隨有γ射線。其中主要由熱中子束與被患者S體內的腫瘤攝入之硼進行核反應,而發揮有效的治療效果。中子束N之射束中所含的超熱中子束的一部分,亦在患者S之體內減速而成為發揮上述治療效果之超熱中子束。 A collimator 14 for specifying an irradiation range in which the neutron beam N illuminates the patient S is disposed in front of the decelerating material 12. In the neutron beam generating unit 9, the charged particle beam P illuminates the target T, thereby generating the neutron beam N. The generated neutron beam N is decelerated by the decelerating material 12. The neutron beam N is emitted from the decelerating material 12 and passes through the collimator 14 and then irradiated to the patient S on the treatment table 2. The neutron beam N includes a high-speed neutron beam, an epithermal neutron beam, and a thermal neutron beam, which are also accompanied by gamma rays. Among them, the thermal neutron beam is nuclearly reacted with boron taken up by the tumor in the patient S to exert an effective therapeutic effect. A part of the epithermal neutron beam contained in the beam of the neutron beam N is also decelerated in the body of the patient S to become an epithermal neutron beam that exhibits the above-described therapeutic effect.
準直器14例如為外形呈圓形形狀之平板。準直器14的外形形狀與設置於後述照射室4的照射口16之內表面形狀相對應。在準直器14上設置有用於規定照射範圍之例如圓形開口14a。藉由使患者S的姿勢相對於開口14a保持在既定位置,能夠將通過開口14a的中子束N照射於患者S之既定照射目標。本例子中,準直器14配置成, 使通過照射場的中心(開口14a的中心)之照射中心軸線C位於X軸上。 The collimator 14 is, for example, a flat plate having a circular shape. The outer shape of the collimator 14 corresponds to the inner surface shape of the irradiation port 16 provided in the irradiation chamber 4 to be described later. For example, a circular opening 14a for defining an irradiation range is provided on the collimator 14. By keeping the posture of the patient S at a predetermined position with respect to the opening 14a, the neutron beam N passing through the opening 14a can be irradiated to the predetermined irradiation target of the patient S. In this example, the collimator 14 is configured such that The illumination center axis C passing through the center of the irradiation field (the center of the opening 14a) is placed on the X-axis.
參閱第1圖對照射室4進行說明。照射室4為用於將中子束N照射於患者S且將患者S配置在室內的房間。照射室4具有被混凝土製屏蔽壁包圍的屏蔽空間。在照射室4的出入口設置有能夠開閉之一對門D1、D1。照射室4的出入口具有能夠供治療台2通行之尺寸。更具體而言,照射室4的出入口具有:能夠供後述頂板41的長邊方向沿著Y軸方向的狀態(第4圖(c)的狀態)的治療台2通行之尺寸。此外,本例子中,照射室4的出入口的X軸方向的寬度小於頂板41的長邊方向的長度L(第2圖)。因此,在頂板41的長邊方向沿著X軸的狀態下,治療台2無法在照射室4的出入口通行。因為為了節省空間及確保放射線的屏蔽性,宜盡量將照射室4的出入口縮窄。亦即,在一對門D1、D1被打開的狀態下,形成於該等門之間的開口M1的寬度(一對門D1、D1在開閉方向上的寬度)WD1小於頂板41的長邊方向的長度L。換言之,使治療台2通過時因一對門D1、D1打開所形成之開口M1的寬度WD1小於頂板41的長邊方向的長度L。另外,也可以將供治療台2通過時的開口M1的寬度WD1設定為小於一對門D1、D1開得最大狀態下的開口M1的寬度。此外,一對門D1、D1可以構成為雙方皆為可動,亦可以構成為僅使其中一個門相對於另一個門可動。 The irradiation chamber 4 will be described with reference to Fig. 1 . The irradiation room 4 is a room for irradiating the neutron beam N to the patient S and arranging the patient S indoors. The irradiation chamber 4 has a shielding space surrounded by a concrete shielding wall. A pair of doors D1 and D1 that can open and close are provided at the entrance and exit of the irradiation chamber 4. The entrance and exit of the irradiation chamber 4 has a size that allows the treatment table 2 to pass. More specifically, the entrance and exit of the irradiation chamber 4 has a size that allows the treatment table 2 to pass through the state in which the longitudinal direction of the top plate 41 to be described later is along the Y-axis direction (the state of FIG. 4(c)). Further, in the present example, the width of the entrance and exit of the irradiation chamber 4 in the X-axis direction is smaller than the length L of the longitudinal direction of the top plate 41 (second drawing). Therefore, in a state where the longitudinal direction of the top plate 41 is along the X-axis, the treatment table 2 cannot pass through the entrance and exit of the irradiation chamber 4. In order to save space and ensure shielding of radiation, it is desirable to narrow the entrance and exit of the irradiation chamber 4 as much as possible. That is, in a state where the pair of doors D1, D1 are opened, the width of the opening M1 (the width of the pair of doors D1, D1 in the opening and closing direction) formed between the doors is smaller than the length of the longitudinal direction of the top plate 41. L. In other words, the width WD1 of the opening M1 formed by opening the pair of doors D1 and D1 when the treatment table 2 is passed is smaller than the length L of the longitudinal direction of the top plate 41. Further, the width WD1 of the opening M1 when the treatment table 2 is passed may be set to be smaller than the width of the opening M1 in the maximum state in which the pair of doors D1 and D1 are opened. Further, the pair of doors D1, D1 may be configured to be movable on both sides, or may be configured such that only one of the doors is movable relative to the other door.
在屏蔽體13的照射室4側的表面設置有護罩15(壁 部)。護罩15構成照射室4的內壁面的一部分。在護罩15設置有成為中子束N的出入口之照射口16。在照射口16嵌入有準直器14。照射口16在X軸方向開口,且內表面呈圓形形狀。 A shield 15 (wall) is provided on the surface of the shield 13 on the side of the irradiation chamber 4 unit). The shield 15 constitutes a part of the inner wall surface of the irradiation chamber 4. The shield 15 is provided with an irradiation port 16 that serves as an entrance and exit of the neutron beam N. A collimator 14 is embedded in the irradiation port 16. The irradiation port 16 is opened in the X-axis direction, and the inner surface has a circular shape.
準備室3為用於在照射室4進行向患者S照射中子束N時的所需作業之房間。在準備室3內,例如將患者S束縛在治療台2、調整準直器14與患者S之間的位置關係。因此,準備室3的尺寸為可供作業人員在收容於室內的治療台2的周圍輕鬆地實施準備作業之尺寸。在準備室3的出入口設置有能夠開閉之一對門D2、D2。準備室3的出入口的尺寸例如與照射室4的出入口相同程度的尺寸。準備室3的出入口亦與照射室4同樣,宜盡量縮窄。亦即,在一對門D2、D2被打開的狀態下,形成於該等門之間的開口M2的寬度(一對門D2、D2在開閉方向上的寬度)WD2小於頂板41的長邊方向的長度L。 The preparation chamber 3 is a room for performing a required operation when irradiating the patient S with the neutron beam N in the irradiation chamber 4. In the preparation chamber 3, for example, the patient S is restrained at the treatment table 2, and the positional relationship between the collimator 14 and the patient S is adjusted. Therefore, the size of the preparation chamber 3 is a size that can be easily prepared by the worker around the treatment table 2 housed in the room. A pair of doors D2 and D2 capable of opening and closing are provided at the entrance and exit of the preparation chamber 3. The size of the entrance and exit of the preparation chamber 3 is, for example, the same size as the entrance and exit of the irradiation chamber 4. The entrance and exit of the preparation chamber 3 are also the same as the irradiation chamber 4, and it is preferable to narrow as much as possible. That is, in a state where the pair of doors D2, D2 are opened, the width of the opening M2 formed between the doors (the width of the pair of doors D2, D2 in the opening and closing direction) WD2 is smaller than the length of the longitudinal direction of the top plate 41. L.
此外,在準備室3內設置有:用於在與照射室4內照射中子束N時相同的狀態下設置治療台2及準直器14之壁部17。在壁部17設置有與照射口16相同形狀的虛擬照射口18。進行設置時,在虛擬照射口18嵌入準直器14。對於使用虛擬照射口18來對準直器14與患者S進行對準之方法隨後敘述。 Further, in the preparation chamber 3, a wall portion 17 for providing the treatment table 2 and the collimator 14 in the same state as when the neutron beam N is irradiated in the irradiation chamber 4 is provided. The wall portion 17 is provided with a virtual irradiation port 18 having the same shape as the irradiation port 16. When the setting is made, the collimator 14 is inserted into the virtual irradiation port 18. The method of aligning the straightener 14 with the patient S using the virtual illumination port 18 is described later.
聯絡室5為連通準備室3與照射室4並讓處於束縛患者S的狀態之治療台2移動的房間。聯絡室5具有能夠供治療台2通過之寬度。更具體而言,聯絡室5的尺寸為能 夠供後述頂板41的長邊方向沿著Y軸方向的狀態(第4圖(c)的狀態)的治療台2通行之尺寸。此外,本例子中,聯絡室5的X軸方向的寬度小於頂板41的長邊方向的長度L。因此,在頂板41的長邊方向沿著X軸的狀態下,無法使治療台2在聯絡室5通行。聯絡室5亦與照射室4同樣,宜盡量縮窄。 The communication room 5 is a room that connects the preparation room 3 and the irradiation room 4 and moves the treatment table 2 in a state in which the patient S is restrained. The communication room 5 has a width that allows the treatment table 2 to pass. More specifically, the size of the communication room 5 is The size of the treatment table 2 in the state in which the longitudinal direction of the top plate 41 to be described later is along the Y-axis direction (the state of FIG. 4(c)) is sufficient. Further, in the present example, the width of the communication chamber 5 in the X-axis direction is smaller than the length L of the top plate 41 in the longitudinal direction. Therefore, in a state where the longitudinal direction of the top plate 41 is along the X-axis, the treatment table 2 cannot be made to pass through the communication chamber 5. The communication room 5 is also the same as the irradiation room 4, and should be narrowed as much as possible.
此外,中子捕獲治療系統1還具備用於使治療台2在準備室3與照射室4之間行走之一對的導軌19。導軌19從準備室3的內部通過聯絡室5延伸至照射室4的內部,沿著X軸呈直線狀設置。 Further, the neutron capture treatment system 1 further includes a guide rail 19 for moving the treatment table 2 between the preparation chamber 3 and the irradiation chamber 4. The guide rail 19 extends from the inside of the preparation chamber 3 through the communication chamber 5 to the inside of the irradiation chamber 4, and is linearly arranged along the X-axis.
接著,對治療台2進行說明。第3圖係顯示治療台2的圖。如第3圖所示,治療台2具備:沿著地面F行走的行走部30、具有載置患者S的頂板41(載置部)的底座部40(第1旋轉部)、及供安裝準直器14之準直器安裝部50(第2旋轉部)。底座部40設置於行走部30上,準直器安裝部50設置於底座部40上。亦即,頂板41及準直器14設置於行走部30上。 Next, the treatment table 2 will be described. Figure 3 is a diagram showing the treatment table 2. As shown in Fig. 3, the treatment table 2 includes a traveling portion 30 that travels along the ground F, a base portion 40 (first rotating portion) that has a top plate 41 (mounting portion) on which the patient S is placed, and a mounting plate The collimator mounting portion 50 (second rotating portion) of the straightener 14. The base portion 40 is provided on the traveling portion 30, and the collimator mounting portion 50 is provided on the base portion 40. That is, the top plate 41 and the collimator 14 are disposed on the running portion 30.
行走部30具有:沿著地面F朝向Y軸方向移動之基底部31、及配置於基底部31上且相對於基底部31朝向X軸方向移動(橫移)之橫移部33。基底部31的外形例如呈長方體狀的形狀。基底部31配置於治療台2的最下部,且在導軌19上移動。作為實現該移動之構造,在本例子中,基底部31具有一對的驅動部32(第2圖)。驅動部32例如藉由設置於基底部31內的皮帶機構等驅動, 並按照來自控制裝置的指示使基底部31沿著導軌19滑動移動。 The traveling portion 30 has a base portion 31 that moves in the Y-axis direction along the floor surface F, and a traverse portion 33 that is disposed on the base portion 31 and that moves (traverses) in the X-axis direction with respect to the base portion 31. The outer shape of the base portion 31 has, for example, a rectangular parallelepiped shape. The base portion 31 is disposed at the lowermost portion of the treatment table 2 and moves on the guide rail 19. As a structure for realizing this movement, in the present example, the base portion 31 has a pair of driving portions 32 (second drawing). The drive unit 32 is driven by, for example, a belt mechanism or the like provided in the base portion 31. The base portion 31 is slidably moved along the guide rail 19 in accordance with an instruction from the control device.
橫移部33的外形例如呈長方體狀的形狀。如第2圖中箭頭B所示,橫移部33相對於基底部31朝向X軸方向移動,藉此使底座部40及準直器安裝部50相對於基底部31朝向X軸方向(基底部31的移動方向亦即與Y軸方向正交的方向)移動。作為用於該移動的機構,在本例子中,橫移部33具有設置於其與基底部31之間的一對的移動機構35。移動機構35例如包含:在基底部31上沿著X軸方向而設之導軌、設置於橫移部33的下表面且可滑動地卡合於導軌之滑塊等,按照來自控制裝置的指示使橫移部33相對於基底部31滑動移動。 The outer shape of the traverse portion 33 has, for example, a rectangular parallelepiped shape. As indicated by an arrow B in FIG. 2, the traverse portion 33 moves in the X-axis direction with respect to the base portion 31, whereby the base portion 40 and the collimator mounting portion 50 are oriented in the X-axis direction with respect to the base portion 31 (base portion). The moving direction of 31 is the direction orthogonal to the Y-axis direction). As a mechanism for the movement, in the present example, the traverse portion 33 has a pair of movement mechanisms 35 provided between the yaw portion 33 and the base portion 31. The moving mechanism 35 includes, for example, a guide rail provided on the base portion 31 along the X-axis direction, a slider provided on the lower surface of the traverse portion 33 and slidably engaged with the guide rail, and the like, in accordance with an instruction from the control device. The traverse portion 33 slides with respect to the base portion 31.
底座部40具有:載置患者S之頂板41、支撐頂板41的伸縮部43、及支撐伸縮部43的台車部45。頂板41形成為平板狀,例如長邊方向的一側的外形呈圓弧形狀,剩餘部分的外形呈矩形形狀。在頂板41上載置躺臥狀態(臥位)的患者S時,在該圓弧狀部分配置頭部。頂板41的長邊方向的長度為能夠使患者S的身體躺臥之長度(例如2m左右)。伸縮部43沿Z軸方向延伸,且能夠按照來自控制裝置的指示沿Z軸方向伸縮。 The base portion 40 has a top plate 41 on which the patient S is placed, an expansion-contraction portion 43 that supports the top plate 41, and a carriage portion 45 that supports the expansion-contraction portion 43. The top plate 41 is formed in a flat plate shape. For example, the outer shape of one side in the longitudinal direction has an arc shape, and the outer shape of the remaining portion has a rectangular shape. When the patient S in the lying state (recumbent position) is placed on the top plate 41, the head portion is placed in the arcuate portion. The length of the top plate 41 in the longitudinal direction is a length (for example, about 2 m) that allows the body of the patient S to lie down. The expansion and contraction portion 43 extends in the Z-axis direction and can expand and contract in the Z-axis direction in accordance with an instruction from the control device.
台車部45例如呈長方體狀的外形形狀。台車部45在下部具有車輪46,在從橫移部33卸下的狀態,能夠藉由車輪46在地面F上移動。此外,台車部45透過第1旋轉支撐機構(第1旋轉支撐部)47以可旋轉之方式被橫移 部33支撐。第1旋轉支撐機構47例如為內置軸承等之旋轉機構,按照來自控制裝置的指示使台車部45(底座部40)繞旋轉軸A旋轉。亦即,第1旋轉支撐機構47以能夠相對於行走部30一起旋轉的方式支撐頂板41及準直器14。換言之,第1旋轉支撐機構47支撐頂板41與準直器14,使頂板41及準直器14雙方能夠相對於行走部30一體地旋轉。 The truck portion 45 has, for example, a rectangular parallelepiped outer shape. The truck portion 45 has wheels 46 at the lower portion, and is detachable from the traverse portion 33 by the wheels 46 on the floor surface F. Further, the carriage portion 45 is traversed in a rotatable manner by the first rotation support mechanism (first rotation support portion) 47. The part 33 is supported. The first rotation support mechanism 47 is, for example, a rotation mechanism such as a built-in bearing, and rotates the carriage portion 45 (base portion 40) about the rotation axis A in accordance with an instruction from the control device. In other words, the first rotation support mechanism 47 supports the top plate 41 and the collimator 14 so as to be rotatable together with the traveling portion 30. In other words, the first rotation support mechanism 47 supports the top plate 41 and the collimator 14 so that both the top plate 41 and the collimator 14 can integrally rotate with respect to the traveling portion 30.
準直器安裝部50具有:沿Z軸方向延伸之豎起片51、及沿水平方向延伸之水平片53。在豎起片51的上端部,可裝卸地安裝著準直器14。水平片53的一端部與豎起片51的下端部相連,在另一端部透過第2旋轉支撐機構(第2旋轉支撐部)55以可旋轉之方式被台車部45支撐。本例子中,第2旋轉支撐機構55的旋轉軸與第1旋轉支撐機構47的旋轉軸A相同。第2旋轉支撐機構55例如為內置軸承等的旋轉機構,按照來自控制裝置之指示使水平片53(準直器安裝部50)繞旋轉軸A旋轉。亦即,準直器安裝部50具有支撐準直器14使其能夠相對於頂板41旋轉之第2旋轉支撐機構55,並以能夠調整準直器14相對於行走部30的位置之方式支撐準直器14。 The collimator mounting portion 50 has a rising piece 51 extending in the Z-axis direction and a horizontal piece 53 extending in the horizontal direction. A collimator 14 is detachably attached to the upper end portion of the riser piece 51. One end portion of the horizontal piece 53 is connected to the lower end portion of the rising piece 51, and the other end portion is rotatably supported by the carriage portion 45 via the second rotation support mechanism (second rotation support portion) 55. In the present example, the rotation axis of the second rotation support mechanism 55 is the same as the rotation axis A of the first rotation support mechanism 47. The second rotation support mechanism 55 is, for example, a rotation mechanism such as a built-in bearing, and rotates the horizontal piece 53 (collimator attachment portion 50) about the rotation axis A in accordance with an instruction from the control device. That is, the collimator mounting portion 50 has the second rotation support mechanism 55 that supports the collimator 14 so as to be rotatable relative to the top plate 41, and supports the position of the collimator 14 with respect to the traveling portion 30. Straight 14.
接著,對利用中子捕獲治療系統1進行之治療流程進行說明。第4圖及第5圖係顯示進行治療時之治療台的移動狀態的概略俯視圖。首先,在進入中子捕獲治療系統1之前對患者S實施既定的準備作業。接著,使患者S及作業人員進入準備室3,使患者S在頂板41上躺臥。而 且,作業人員利用束縛件將患者S的身體束縛在頂板41上。 Next, the treatment procedure performed by the neutron capture treatment system 1 will be described. Fig. 4 and Fig. 5 are schematic plan views showing the movement state of the treatment table at the time of treatment. First, a predetermined preparation operation is performed on the patient S before entering the neutron capture treatment system 1. Next, the patient S and the worker are placed in the preparation room 3, and the patient S is placed on the top plate 41. and Moreover, the operator binds the body of the patient S to the top plate 41 by means of a restraining member.
之後,由作業人員調整患者S內的照射目標與準直器14之間的位置關係,對患者S與準直器14進行對準。之後,作業人員使橫移部33朝向壁部17側移動,並在壁部17的虛擬照射口18中嵌入準直器14。藉此,在準備室3內,以與在照射室4內照射中子束N時相同的狀態設置治療台2及準直器14。第4圖(a)顯示在該準備室3內結束設置的狀態的一例。 Thereafter, the operator adjusts the positional relationship between the irradiation target in the patient S and the collimator 14 to align the patient S with the collimator 14. Thereafter, the worker moves the traverse portion 33 toward the wall portion 17 side, and the collimator 14 is fitted into the virtual irradiation port 18 of the wall portion 17. Thereby, in the preparation chamber 3, the treatment table 2 and the collimator 14 are provided in the same state as when the neutron beam N is irradiated in the irradiation chamber 4. Fig. 4(a) shows an example of a state in which the installation is completed in the preparation room 3.
更具體而言,進行該設置時,藉由準直器安裝部50(第2旋轉支撐機構55)的旋轉,調整準直器14相對於頂板41的位置關係,而進行準直器14與患者S的對準。此外,藉由底座部40(第1旋轉支撐機構47)的旋轉,使底座部40及準直器安裝部50雙方相對於行走部30一體地旋轉,使準直器14的中心位在X軸上。接著,使橫移部33朝向壁部17側移動,在虛擬照射口18嵌入準直器14。另外,上述底座部40的旋轉與準直器安裝部50的旋轉可以同時實施,亦可以先實施其中任一方的旋轉。此外,在進行設置時,藉由伸縮部43的伸縮調整頂板41與準直器14在Z軸方向上的位置關係。 More specifically, when this setting is performed, the positional relationship of the collimator 14 with respect to the top plate 41 is adjusted by the rotation of the collimator mounting portion 50 (second rotation support mechanism 55), and the collimator 14 and the patient are performed. S alignment. Further, both the base portion 40 and the collimator mounting portion 50 are integrally rotated with respect to the traveling portion 30 by the rotation of the base portion 40 (the first rotation support mechanism 47), so that the center of the collimator 14 is on the X-axis. on. Next, the traverse portion 33 is moved toward the wall portion 17 side, and the collimator 14 is fitted into the virtual irradiation port 18. Further, the rotation of the base portion 40 and the rotation of the collimator mounting portion 50 may be performed simultaneously, or one of the rotations may be performed first. Further, at the time of installation, the positional relationship between the top plate 41 and the collimator 14 in the Z-axis direction is adjusted by the expansion and contraction of the elastic portion 43.
接著,使治療台2朝向照射室4移動。首先,如第4圖(b)所示,橫移部33朝向遠離壁部17之一側移動,使準直器14從虛擬照射口18脫離。接著,如第4圖(c)所示,底座部40進行旋轉,而成為使頂板41的長 邊方向沿著Y軸方向的狀態。在該狀態下,基底部31沿Y軸方向移動,使治療台2從準備室3通過聯絡室5移動至照射室4(第5圖(a))。此時,頂板41的長邊方向成為沿著Y軸方向的狀態,因此準備室3的出入口(門D2)、照射室4的出入口(門D1)、聯絡室5的內壁不會與頂板41互相干擾。此外,當底座部40旋轉時,由於底座部40與準直器安裝部50一體地旋轉,頂板41與準直器14之間的位置關係保持進行設置時的狀態。 Next, the treatment table 2 is moved toward the irradiation chamber 4. First, as shown in FIG. 4(b), the traverse portion 33 moves toward one side away from the wall portion 17, and the collimator 14 is detached from the virtual irradiation port 18. Next, as shown in FIG. 4(c), the base portion 40 is rotated to become the length of the top plate 41. The state of the side direction along the Y-axis direction. In this state, the base portion 31 moves in the Y-axis direction, and the treatment table 2 is moved from the preparation chamber 3 through the communication chamber 5 to the irradiation chamber 4 (Fig. 5(a)). At this time, since the longitudinal direction of the top plate 41 is in the Y-axis direction, the entrance and exit of the preparation chamber 3 (the door D2), the entrance and exit of the irradiation chamber 4 (the door D1), and the inner wall of the communication chamber 5 are not combined with the top plate 41. Interfere with each other. Further, when the base portion 40 is rotated, since the base portion 40 is integrally rotated with the collimator mounting portion 50, the positional relationship between the top plate 41 and the collimator 14 is maintained in a state of being set.
接著,在照射室4進行中子束N的照射準備。首先,如第5圖(b)所示,底座部40旋轉至設置時(第4圖(a))的位置。此時也是,由於底座部40與準直器安裝部50一體地旋轉,頂板41與準直器14之間的位置關係保持設置時的狀態。接著,如第5圖(c)所示,橫移部33朝向壁部17側移動,在照射口16嵌入準直器14。藉此,準確地重現設置時的狀態,使準直器14及患者S以既定的位置關係配置。之後,開始朝向患者S照射中子束N。 Next, irradiation preparation of the neutron beam N is performed in the irradiation chamber 4. First, as shown in Fig. 5(b), the base portion 40 is rotated to the position at the time of installation (Fig. 4(a)). At this time, also, since the base portion 40 and the collimator mounting portion 50 are integrally rotated, the positional relationship between the top plate 41 and the collimator 14 is maintained at the state in which it is set. Next, as shown in FIG. 5(c), the traverse portion 33 moves toward the wall portion 17 side, and the collimator 14 is fitted into the irradiation port 16. Thereby, the state at the time of installation is accurately reproduced, and the collimator 14 and the patient S are arranged in a predetermined positional relationship. Thereafter, the neutron beam N is started to be directed toward the patient S.
如以上說明,在本實施形態的治療台2,在進行設置時,藉由準直器安裝部50調整準直器14相對於頂板41(患者S)的位置關係,將頂板41與準直器14進行對準。此外,在移動治療台2時,藉由旋轉第1旋轉支撐機構47,使頂板41及準直器14一起相對於行走部30旋轉,使頂板41成為不與準備室3的門等互相干擾的狀態。此時,由於頂板41與準直器14一體地旋轉,頂板 41與準直器14的位置關係不發生變化。而且,移動結束之後,藉由使第1旋轉支撐機構47旋轉至設置時的位置,能夠準確地重現設置時的狀態。因此,依據治療台2,能夠保持準直器14與患者S的位置關係並將治療台2移動到照射室4。 As described above, in the treatment table 2 of the present embodiment, when the setting is performed, the positional relationship of the collimator 14 with respect to the top plate 41 (patient S) is adjusted by the collimator mounting portion 50, and the top plate 41 and the collimator are adjusted. 14 Alignment. Further, when the treatment table 2 is moved, the top plate 41 and the collimator 14 are rotated together with respect to the traveling portion 30 by rotating the first rotation support mechanism 47, so that the top plate 41 does not interfere with the door or the like of the preparation chamber 3. status. At this time, since the top plate 41 rotates integrally with the collimator 14, the top plate The positional relationship between the 41 and the collimator 14 does not change. Further, after the end of the movement, by rotating the first rotation support mechanism 47 to the position at the time of installation, it is possible to accurately reproduce the state at the time of installation. Therefore, according to the treatment table 2, the positional relationship between the collimator 14 and the patient S can be maintained and the treatment table 2 can be moved to the irradiation room 4.
此外,例如可能使患者S的頭部直接接觸準直器14、或隔著若干間隙使患者S的頭部接近準直器14,來將患者S與準直器14進行對準。這是因為,若患者S的頭部與準直器14之間的間隙較大,則中子束會從該間隙洩漏,而導致照射效率下降。在如此般使患者S與準直器14接觸或接近的狀態下,若像以往的中子捕獲治療系統那樣在將準直器14固定在治療台2的基座部(行走部30)狀態使頂板41相對於基座部旋轉,則可能導致一邊讓頂板41上的患者S的頭部與準直器14之間摩擦一邊使頂板41旋轉。此時,有可能導致患者S的姿勢發生變化,例如有可能導致患者S的頸部稍稍傾斜而改變頭部的方向。若患者S的姿勢發生變化,即便在將治療台2移動到照射室4之後旋轉頂板41,仍無法將患者S與準直器14之間的位置關係恢復到設置時的位置關係。 In addition, the patient S can be aligned with the collimator 14 by, for example, having the head of the patient S directly contact the collimator 14, or having the head of the patient S approach the collimator 14 across a plurality of gaps. This is because if the gap between the head of the patient S and the collimator 14 is large, the neutron beam leaks from the gap, resulting in a decrease in the irradiation efficiency. When the patient S is brought into contact with or close to the collimator 14 in this manner, the collimator 14 is fixed to the base portion (the traveling portion 30) of the treatment table 2 as in the conventional neutron capture treatment system. Rotation of the top plate 41 with respect to the base portion may cause the top plate 41 to rotate while rubbing the head of the patient S on the top plate 41 with the collimator 14. At this time, there is a possibility that the posture of the patient S changes, for example, it is possible to cause the neck of the patient S to slightly tilt to change the direction of the head. If the posture of the patient S changes, even if the top plate 41 is rotated after moving the treatment table 2 to the irradiation chamber 4, the positional relationship between the patient S and the collimator 14 cannot be restored to the positional relationship at the time of setting.
在這點上,在本實施形態的治療台2,在移動治療台2時,藉由第1旋轉支撐機構47使頂板41及準直器14一起相對於行走部30旋轉,因此頂板41與準直器14的位置關係不發生變化。因此,能夠抑制如上述般使患者S的頭部與準直器14之間摩擦而導致患者S的姿勢發生變 化。 In this regard, in the treatment table 2 of the present embodiment, when the treatment table 2 is moved, the top plate 41 and the collimator 14 are rotated together with respect to the traveling portion 30 by the first rotation support mechanism 47, so the top plate 41 and the standard The positional relationship of the straightener 14 does not change. Therefore, it is possible to suppress the friction between the head of the patient S and the collimator 14 as described above, causing the posture of the patient S to change. Chemical.
此外,在本實施形態的治療台2,準直器安裝部50具有:以能夠相對於頂板41旋轉的方式支撐準直器14之第2旋轉支撐機構55。藉此,能夠以簡單的構造藉由準直器安裝部50調整準直器14相對於頂板41的位置。 Further, in the treatment table 2 of the present embodiment, the collimator attachment portion 50 has a second rotation support mechanism 55 that supports the collimator 14 so as to be rotatable relative to the top plate 41. Thereby, the position of the collimator 14 with respect to the top plate 41 can be adjusted by the collimator mounting part 50 with a simple structure.
此外,在本實施形態的治療台2,第1旋轉支撐機構47的旋轉軸與第2旋轉支撐機構55的旋轉軸位於同一直線上,不論是讓第1旋轉支撐機構47及第2旋轉支撐機構55的哪個旋轉,準直器安裝部50都在同一圓周上移動,因此容易將準直器14的位置及姿勢與照射口16進行對準。 Further, in the treatment table 2 of the present embodiment, the rotation axis of the first rotation support mechanism 47 and the rotation axis of the second rotation support mechanism 55 are on the same straight line, regardless of whether the first rotation support mechanism 47 and the second rotation support mechanism are provided. Which of the 55 rotations and the collimator mounting portion 50 move on the same circumference, it is easy to align the position and posture of the collimator 14 with the irradiation port 16.
此外,在本實施形態的治療台2,將準直器14設置在既定位置之後,藉由橫移部33朝向X軸方向使第1旋轉支撐機構47移動,從而能夠將準直器14嵌入於照射口16。因此,相較於例如由作業人員等移動能夠在地面F上朝向任意方向移動的治療台來將準直器14嵌入於照射口16的情況,能夠輕鬆準確地將準直器14嵌入於照射口16。 Further, in the treatment table 2 of the present embodiment, after the collimator 14 is placed at a predetermined position, the first rotation support mechanism 47 is moved in the X-axis direction by the traverse portion 33, whereby the collimator 14 can be embedded. Irradiation port 16. Therefore, the collimator 14 can be easily and accurately embedded in the irradiation port as compared with the case where the collimator 14 is embedded in the irradiation port 16 by a treatment table that can be moved in any direction on the floor F by, for example, a worker or the like. 16.
以上,對本發明之較佳實施形態進行了說明,但本發明並不限定於上述實施形態,可以在不改變各請求項所記載的要旨的範圍內進行變形,或者應用於其他實施形態。 The preferred embodiments of the present invention have been described above, but the present invention is not limited to the above-described embodiments, and modifications may be made without departing from the gist of the claims.
例如,上述實施形態中,對支撐底座部40使其能夠相對於行走部30旋轉且支撐準直器安裝部50使其能夠相對於底座部40旋轉之例子進行了說明,但亦可以係支撐 準直器安裝部50使其能夠相對於行走部30旋轉,且支撐底座部40使其能夠相對於準直器安裝部50旋轉。此外,上述實施形態中,對第1旋轉支撐機構47的旋轉軸與第2旋轉支撐機構55的旋轉軸位於同一直線上的例子進行了說明,但第1旋轉支撐機構47的旋轉軸與第2旋轉支撐機構55的旋轉軸亦可以不位於同一直線上。 For example, in the above-described embodiment, the example in which the support base portion 40 is rotatable relative to the traveling portion 30 and supports the collimator mounting portion 50 so as to be rotatable relative to the base portion 40 has been described. However, it may be supported. The collimator mounting portion 50 is rotatable relative to the running portion 30 and supports the base portion 40 so as to be rotatable relative to the collimator mounting portion 50. Further, in the above-described embodiment, the example in which the rotation axis of the first rotation support mechanism 47 and the rotation axis of the second rotation support mechanism 55 are on the same straight line has been described, but the rotation axis of the first rotation support mechanism 47 and the second The rotation axes of the rotation support mechanism 55 may not be on the same straight line.
此外,上述實施形態中,對具有使底座部40及準直器安裝部50朝向X軸方向移動之橫移部33的例子進行了說明,但亦可以不具有橫移部33。此時,只要藉由其他移動機構來使治療台2橫移即可。此外,對照射口16在X軸方向開口,且橫移部33使第1旋轉支撐機構47朝向X軸方向移動的例子進行了說明,但例如當照射口16在與Y軸方向交叉的方向開口時,可以朝向該方向移動。此外,上述實施形態中,關於頂板41,以載置躺臥狀態的患者S的臥位用形狀為例進行了說明,但亦可以係載置坐姿狀態的患者S的座位用形狀。 Further, in the above-described embodiment, the example in which the traverse portion 33 that moves the base portion 40 and the collimator mounting portion 50 in the X-axis direction has been described. However, the traverse portion 33 may not be provided. At this time, the treatment table 2 can be traversed by other moving mechanisms. Further, although the example in which the irradiation port 16 is opened in the X-axis direction and the traverse portion 33 moves the first rotation support mechanism 47 in the X-axis direction has been described, for example, the irradiation port 16 is opened in a direction crossing the Y-axis direction. When you move, you can move in that direction. In the above-described embodiment, the shape of the lying position of the patient S in the lying state is described as an example. However, the seat shape of the patient S in the sitting state may be placed.
並且,上述實施形態中,準直器安裝部50能夠藉由第2旋轉支撐機構55調整準直器14相對於頂板41的位置,但並不限於此。例如,準直器安裝部50亦可以具有能夠進行3維位置調節的多關節臂,藉由該多關節臂調整準直器14相對於頂板41的位置。該多關節臂例如構成為,其基端部固定於底座部40,在其前端部安裝有準直器14,使前端部相對於基端部進行移動來調整準直器14相對於頂板41的位置。 Further, in the above-described embodiment, the collimator mounting portion 50 can adjust the position of the collimator 14 with respect to the top plate 41 by the second rotation support mechanism 55, but is not limited thereto. For example, the collimator mounting portion 50 may have a multi-joint arm capable of three-dimensional position adjustment, and the multi-joint arm adjusts the position of the collimator 14 with respect to the top plate 41. The multi-joint arm is configured, for example, such that a proximal end portion thereof is fixed to the base portion 40, a collimator 14 is attached to the distal end portion thereof, and the distal end portion is moved relative to the proximal end portion to adjust the collimator 14 with respect to the top plate 41. position.
此外,上述實施形態中,在照射室4的出入口設置有門D1且在準備室3的出入口設置有門D2,但只要在照射室4側設有門D1即可,可以省略準備室3側的門D2。 Further, in the above-described embodiment, the door D1 is provided at the entrance and exit of the irradiation chamber 4, and the door D2 is provided at the entrance and exit of the preparation chamber 3. However, the door D1 may be provided on the irradiation chamber 4 side, and the preparation chamber 3 side may be omitted. Door D2.
2‧‧‧治療台(中子捕獲治療用治療台) 2‧‧‧ treatment table (treatment table for neutron capture therapy)
14‧‧‧準直器 14‧‧‧ collimator
19‧‧‧導軌 19‧‧‧ rails
30‧‧‧行走部 30‧‧‧ Walking Department
31‧‧‧基底部 31‧‧‧ base
33‧‧‧橫移部 33‧‧‧ traverse
35‧‧‧移動機構 35‧‧‧Mobile agencies
41‧‧‧頂板 41‧‧‧ top board
40‧‧‧底座部 40‧‧‧Base section
43‧‧‧伸縮部 43‧‧‧Flexing Department
45‧‧‧台車部 45‧‧‧Train Department
46‧‧‧車輪 46‧‧‧ Wheels
47‧‧‧第1旋轉支撐機構(第1旋轉支撐部) 47‧‧‧1st rotation support mechanism (1st rotation support part)
50‧‧‧準直器安裝部 50‧‧‧collimator installation
51‧‧‧豎起片 51‧‧‧ erected
53‧‧‧水平片 53‧‧‧ horizontal film
55‧‧‧第二旋轉支撐機構 55‧‧‧Second rotary support mechanism
A‧‧‧旋轉軸 A‧‧‧Rotary axis
S‧‧‧患者(被照射體) S‧‧‧ patients (irradiated body)
F‧‧‧地面 F‧‧‧ Ground
Claims (6)
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CN106353345B (en) * | 2016-08-12 | 2019-03-05 | 上海蓝十字脑科医院有限公司 | Device is observed with radioreaction by dept. of radiology |
CN107890611B (en) * | 2017-11-24 | 2024-01-26 | 北京新核核工程科技有限公司 | Adjusting device and neutron radiation therapy system |
CN110152202A (en) * | 2018-02-01 | 2019-08-23 | 青岛大学附属医院 | A kind of clinical therapy of tumor equipment and its application method |
CN110496321B (en) * | 2018-05-18 | 2024-04-19 | 中硼(厦门)医疗器械有限公司 | Neutron capture treatment system and carrying table |
JP2020146109A (en) * | 2019-03-11 | 2020-09-17 | 住友重機械工業株式会社 | Fixing device for neutron capture therapy, top plate for travel device and neutron capture therapy facility |
TWI712436B (en) * | 2019-05-07 | 2020-12-11 | 禾榮科技股份有限公司 | Neutron beam generating device |
WO2023190522A1 (en) * | 2022-03-31 | 2023-10-05 | 住友重機械工業株式会社 | Neutron capture therapy device |
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