TWI503078B - Plant disease control composition and its use - Google Patents

Description

Plant disease control composition and use thereof

The present invention relates to a plant disease control composition and use thereof.

Many compounds for controlling plant diseases have been developed and have been used (see, for example, PTL 1 and PTL 2).

[reference list] [Patent Document]

[PTL 1]: WO86/02641

[PTL2]: WO92/12970

An object of the present invention is to provide a composition which has an excellent effect of preventing plant diseases.

The inventors of the present invention conducted research in order to find a composition having excellent effects against plant diseases, and found that a composition comprising a formamide compound represented by the following formula (I) and ethaboxam has excellent properties. The plant disease effect is prevented, and thus the present invention has been completed.

The present invention provides the following items [1] to [5].

[1] A plant disease control composition comprising a formamide compound represented by the formula (I): Wherein R ¹ represents a hydrogen atom or a methyl group, and R ² represents a methyl group, a difluoromethyl group or a trifluoromethyl group, and an ethaboxam.

[2] The plant disease control composition according to the above [1], wherein the weight ratio of the formamide compound to the ethaboxam is from 0.1/1 to 10/1 by the form of the carbamide compound.

[3] A method for controlling plant diseases comprising the step of treating a plant or a soil of a growing plant with an effective amount of a formamide compound and ethaboxam, wherein the formamide compound is represented by the formula (I): Wherein R ¹ represents a hydrogen atom or a methyl group, and R ² represents a methyl group, a difluoromethyl group or a trifluoromethyl group.

[4] The method for preventing plant diseases according to the above [3], wherein the weight ratio of the formamide compound to the ethaboxam is from 0.1/1 to 10/1 by the form of the carbamide compound.

[5] The method for preventing plant diseases according to the above [3] or [4], wherein the soil of the plant or the growing plant is soybean or soil for growing soybean, respectively.

According to the present invention, various plant diseases can be prevented.

[Description of specific examples]

The plant disease control composition of the present invention (hereinafter referred to as "composition") contains a formamide compound represented by the formula (I):

Wherein R ¹ and R ² represent the same meanings as defined above (hereinafter referred to as "formamide compound"), and ethaboxam.

"Protonamine compound" is those described, for example, in WO 86/02641 or WO 92/12970, and can be prepared by the methods described therein.

Specific examples of "formamide compounds" are as follows:

A formamide compound represented by the formula (1):

(hereinafter referred to as "methionine compound (1)");

A formamide compound represented by the formula (2):

(hereinafter referred to as "methionine compound (2)");

A formamide compound represented by formula (3):

(hereinafter referred to as "methionine compound (3)"):

A formamide compound represented by formula (4):

(hereinafter referred to as "methionine compound (4)");

A formamide compound represented by the formula (5):

(hereinafter referred to as "formamide compound (5)").

Ethaboxam is a known compound and is described, for example, in "THE PESTICIDE" MANUAL - 14th Edition (BCPC publication) ISBN 1901396142.

This compound can be obtained from a product comprising tebuconazole on the market or can be synthesized by public methods.

In the "composition", the weight ratio of "methionine compound" to ethaboxam is usually from 0.01/1 to 500/1, preferably from 0.1/1 to 10/1. More preferably from 0.1/1 to 3/1.

Although the "composition" may be a mixture of "formamide compound" and ethaboxam itself, the "composition" is usually by mixing "formamide compound", ethaboxam and an inert carrier, and if necessary by adding a surfactant and/or another auxiliary agent for formulation, and by blending the mixture into, for example, an oil formulation, an emulsifiable concentrate, a fluidity formulation, a wettable powder, a water-dispersible granule, a powder, Made by granules, etc. The formulation may be used alone or in combination with another inert ingredient as a plant disease preventive.

In the "composition", the total content of "formamide compound" and ethaboxam is usually from 0.1 to 99% by weight, preferably from 0.2 to 90% by weight, and more preferably from 1 to 80% by weight.

Examples of solid carriers for formulations include, for example, mineral materials such as kaolin, magnesium aluminum sepiolite clay, bentonite, montmorillonite, acid white clay, pyrophyllite, talc, diatomaceous earth, and calcite; natural organic materials. Such as corncob flour and walnut shell flour; synthetic organic materials such as urea; salts such as potassium carbonate and ammonium sulfate; synthetic inorganic materials such as fine powders and granules of synthetic hydrated cerium oxide.

Examples of the liquid carrier include aromatic hydrocarbons such as xylene, alkylbenzene and methylnaphthalene; alcohols such as 2-propanol, ethylene glycol, propylene glycol and ethylene glycol monoethyl ether; ketones such as acetone, cyclohexanone and iso Carbaryl; vegetable oils such as soybean oil and cottonseed oil; petroleum aliphatic hydrocarbons; esters; dimethyl hydrazine; acetonitrile;

Examples of the surfactant include anionic surfactants such as alkyl sulfate salts, alkyl aryl sulfonates, dialkyl sulfosuccinates, polyoxyethylene alkyl aryl ether phosphates, lignin a sulfonate and naphthalene sulfonate formaldehyde polycondensation product; a nonionic surfactant such as a polyoxyethylene alkyl aryl ether, a polyoxyethylene alkyl polyoxypropylene block copolymer - and a sorbitan fatty acid ester; Cationic surfactants such as alkyltrimethylammonium salts.

Examples of other adjuvants for formulation include water-soluble polymers such as polyvinyl alcohol and polyvinylpyrrolidone; polysaccharides such as acacia, alginic acid and salts thereof, CMC (carboxymethylcellulose) or trisin; Inorganic materials such as magnesium aluminum silicate or aluminum oxide sol; preservatives; colorants; and stabilizers such as PAP (acid isopropyl phosphate) and BHT.

The "composition" can be prepared by formulating each "carbamamine compound" and ethaboxam according to the above method, and then diluting each of the obtained formulations with water if necessary, and then mixing the formulation of "formamide compound" and thiazole. A formulation of mycobalamin or a mixed dilution of the formulation.

"Composition" can be used to prevent plant diseases of plants.

Examples of plant diseases that can be prevented by "composition" include the following.

Rice diseases: Magnaporthe grisea, Cochliobolus miyabeanus, Rhizoctonia solani, Gibberella fujikuroi; Wheat disease: Erysiphe graminis, Fusarium graminearum, F. avenaceum, F. culmorum, Microdochium nivale, Puccinia striiformis, stem rust (P. Graminis), P. recondita, Micronectriella nivale, Typhula sp., Ustilago tritici, Tilletia caries, Pseudocercosporella herpotrichoides, Mycosphaerella graminicola, Stagonospora nodorum, Pyrenophora tritici-repentis; Barley disease: Erysiphe graminis, Fusarium graminearum ), F. avenaceum, F. culmorum, Microdochium nivale, Puccinia stri Iformis), stem rust (P. graminis), leaf rust (P. hordei), Ustilago nuda, Rhynchosporium secalis, Pyrenophora teres, Helminthosporium (Cochliobolus sativus), Pyrenophora graminea, Rhizoctonia solani; Corn disease: Ustilago maydis, Cochliobolus heterostrophus, sorghum Gloeocercospora sorghi, Puccinia polysora, Cercospora zeae-maydis, Rhizoctonia solani; Citrus disease: Diaporthe citri, mandarin Elsinoe fawcetti, Penicillium digitatum, P. italicum, Phytophthora parasitica, Phytophthora citrophthora; apple disease: Monilinia mali, Valsa ceratosperma, Podosphaera leucotricha, Alternaria alternata apple Pathotype), Venturia inaequalis, Colletotrichum acutatum, Phytophtora cactorum; Pear disease: Venturia nashicola, V. pirina, Alternaria Alternata Japanese pear pathotype), Gymnosporangium haraeanum, Phytophtora cactorum; peach disease: Monilinia fructicola, Cladosporium carpophilum, Phomopsis sp. Grape disease: Elsinoe ampelina, Glomerella cingulata, Uninula necator, Phakopsora ampelopsidis, Guignardia bidwellii, grape bacterium (Plasmopara viticola); Persimmon disease: Gloesporium kaki, Cercospora kaki, Mycosphaerela nawae; Gourd disease: Colletotrichum lagenarium, melon white Sphaerotheca fuliginea, Mycosphaerella melonis, Fusarium oxysporum , Pseudoperonospora cubensis, Phytophthora sp., Pythium sp.; tomato diseases: Alternaria solani, Cladosporium fulvum, Phytophthora infestans; eggplant disease: Phomopsis vexans, Erysiphe cichoracearum; cruciferous vegetable diseases: Alternaria japonica, Trichosporon sinensis Cercosporella brassicae), Plasmodiophora brassicae, Peronospora parasitica; Scallion disease: Puccinia allii, Peronospora destructor; Soybean disease: Cercospora kikuchii, Elsinoe glycines, Diaporthe phaseolorum var. sojae, Septoria glycines, Cercospora sojina, Phakopsora pachyrhizi, Phytophthora sojae ), Rhizoctonia solani, Corynespora casiicola, Sclerotinia Sclerotiorum); kidney bean disease: Colletrichum lindemthianum; peanut disease: Cercospora personata, Cercospora arachidicola, Sclerotium rolfsii; pea disease: pea white powder Erysiphe pisi; potato disease: Alternaria solani, Phytophthora infestans, Phytophthora erythroseptica, Spongospora subterranean f. sp. Subterranean: strawberry disease: strawberry powdery mildew (Sphaerotheca humuli), Glomerella cingulata; tea disease: Exobasidium reticulatum, Elsinoe leucospila, Pestalotiopsis sp., Anthracnose (Colletotrichum theae-sinensis) Tobacco diseases: Alternaria longipes, Erysiphe cichoracearum, Colletotrichum tabacum, Peronospora tabacina, Phytophthora nicotianae; rapeseed disease: Sclerotinia sclerotiorum Rhizoctonia solani; cotton disease: Rhizoctonia solani; beet disease: Cercospora beticola, Thanatephorus cucumeris, melon Thanatephorus cucumeris), Aphanomyces cochlioides; rose disease: Diplocarpon rosae, Sphaerotheca pannosa, Peronospora sparsa; chrysanthemum and compositae: Bremia lactuca, Septoria chrysanthemi-indici, Puccinia horiana: various plant diseases: Pythium aphanidermatum, Pythium debarianum, Pythium Graminicola), Pythium irregulare, Pythium ultimum, Botrytis cinerea, Sclerotinia sclerotiorum; radish disease: Alternaria brassicicola; crusting Zoysia disease: Sclerotinia homeocarpa, Rhizoctonia solani; Banana disease: Banana black strip Mycosphaerella fijiensis, Mycosphaerella musicola; Sunflower disease: Plasmopara halstedii; various seed diseases caused by the following stages in the growth of various plants: Aspergillus spp., Penicillium spp., Fusarium spp., Gibberella spp., Tricoderma spp., Thieleviopsis spp .), Rhizopus spp., Mucor spp., Corticium spp., Phoma spp., Rhizoctonia spp. ), Diplodia spp. or the like; a viral disease of various plants which are mediated by the Polymixa genus and the Olpidium genus or the like.

Examples of plants in which the "composition" can be used are as follows: crops: corn, rice, wheat, barley, rye, oats, sorghum, cotton, soybeans, peanuts, buckwheat, beets, rapeseed, sunflower, sugar cane, tobacco, etc. Etc.; Vegetables: Solanaceae (eggplant, tomato, green pepper, pepper, potato, etc.), Cucurbitaceae (cucumber, pumpkin, zucchini, watermelon, cantaloupe, zucchini, etc.); cruciferous plant (Japanese radish) , turnip, horseradish, kohlrabi, Chinese cabbage, kale, mustard, broccoli, broccoli, etc.), Asteraceae (Arctium, Artemisia, Artichoke, Western lettuce, etc.), Liliaceae (Leek, Onion) , garlic, asparagus, etc.), umbelliferous plants (carrots, parsley, celery, wild wind, etc.), medlar plants (spinach, leaf beet, etc.), Labiatae (perilla, mint , basil, etc.), strawberry, sweet potato, Japanese yam, Araceae, etc.; flowering plants; foliage plants; fruit trees; pome fruits (apples, pears, Japanese pears, papayas, alfalfa, etc.), Drupe , plum, nectarine, Japanese plum, cherry, apricot, candied dates, etc.), citrus (Wenzhou mandarin orange, orange, lime, lemon, grapefruit, etc.), nuts (chestnuts, walnuts, hazelnuts, almonds, Pistachios, cashews, Hawaiian beans, etc.), berries (blueberries, cranberries, blackberries, raspberries, etc.), grapes, persimmons, olives, alfalfa, bananas, coffee, dates, coconuts, etc. Non-fruit tree; tea tree, mulberry tree, flowering tree, street tree (white layer, birch, hawthorn, eucalyptus, ginkgo, lilac, maple, oak, white yang, bauhinia, maple, sycamore, eucalyptus, Japanese cedar , eucalyptus, Japanese hemlock, juniper, pine, spruce, yew), etc.

The above plants may be those having resistance conferred by genetic engineering techniques.

Among the above plants, the "composition" is expected to have an excellent control effect particularly on plant diseases caused in soybeans.

Among the above plant diseases, the soybean diseases which are expected to have a particularly good effect on the "composition" are Rhizoctonia solani, Cercospora kikuchii, Septoria glycines, stems. Bacteria (Corynespora casiicola), soybean rust (Phakopsora pachyrizi), Sclerotinia sclerotiorum, Cercospora sojina, and the like.

The following composition exemplifies a specific example of "composition": a composition comprising "formamide compound (1)" and ethaboxam; a composition comprising "formamide compound (2)" and thiazole A composition comprising "formamide compound (3)" and ethaboxam; a composition comprising "formamide compound (4)" and ethaboxam; a composition comprising " Methionine compound (5)" and ethaboxam; a composition comprising "formamide compound (1)" and ethaboxam, wherein "methionine compound (1)" versus ethaboxam (ethaboxam) a weight ratio of from 0.1/1 to 10/1; a composition comprising "formamide compound (2)" and ethaboxam, wherein "methionine compound (2)" is thiazolamide (ethaboxam) The weight ratio is from 0.1/1 to 10/1; a composition comprising "formamide compound (3)" and ethaboxam, wherein "carbamamine compound (3)" is based on the weight of ethaboxam a ratio of from 0.1/1 to 10/1; a composition comprising "formamide compound (4)" and ethaboxam, wherein "formamide compound ( 4)" by weight ratio of ethaboxam is from 0.1/1 to 10/1; a composition comprising "formammine compound (5)" and ethaboxam, wherein "mercaptoamine compound (5) The weight ratio of ethaboxam is from 0.1/1 to 10/1; the method for preventing plant diseases (hereinafter referred to as "prevention method") can be carried out by using an effective amount of "formamide compound" It is carried out with the soil of etoxamide treated plants or growing plants.

The plant parts to be treated are the stems and leaves of plants, the seeds or bulbs of plants, and the bulbs represent bulbs, bulbs, rhizomes, tubers, roots and rhizophores.

In the "prevention method", the treatment of the soil of the plant or the growing plant with the "carbamamine compound" and the ethaboxam can be carried out separately at the same time, but in view of convenience, the treatment is usually carried out by using the "composition". get on.

In the "prevention method", treatment with "formamide compound" and ethaboxam is applied, for example, to stem and leaf application, soil application, root application or seed application.

Examples of stem and leaf application include treating the surface of the cultivated plant by spraying the stems and leaves or spraying the stems and trees.

Examples of root application include a method of immersing the roots of whole plants or plants into a liquid containing "formamide compound" and ethaboxam and a solid which will contain "formamide compound", ethaboxam and a solid carrier A method of placing a formulation on the root of a plant.

Examples of soil application include a method of spraying "composition" onto soil, a method of mixing "composition" with soil, and a method of irrigating "composition" to soil.

Examples of seed application include a method of treating a seed or bulb of a plant to be protected against a plant disease with a "composition". In particular, the application can be carried out by spraying a suspension of "composition" onto the surface of the seed or bulb, or by using a wettable powder, an emulsifiable concentrate or a fluid formulation itself or with a small amount of water. The mixture is interspersed on the seed or bulb, or by dipping the seed in a solution of the "composition" for a predetermined period of time, by film coating application or particle coating application.

The amount of "methionine compound" and ethaboxam used in the "prevention method" depends on the kind of the plant to be treated, the type and frequency of the plant disease to be prevented, the type of the formulation, the timing of the treatment, The method of processing, the place of treatment, the weather conditions, and the like are different.

When the "composition" is applied to the stems of plants and/or the leaves or the soil of the growing plants, the total amount of "formamide compound" and ethaboxam is usually from 1 g to 500 g / 1000 m ² , preferably from 2 G to 200 g / 1000 m ² , and more preferably from 10 g to 100 g / 1000 m ² .

When the "composition" is applied to the seed of the plant, the total amount of "formamide compound" and ethaboxam is usually from 0.001 g to 10 g / 1 kg of seed, and preferably from 0.01 g to 1 g / 1 kg of seed. .

Emulsifying concentrates, wettable powders or flowable formulations typically dilute the formulation with water and spray the diluted formulation. In this case, the concentration of "formamide compound" and ethaboxam in the entire diluted formulation is usually from 0.0005% to 2% by weight, and preferably from 0.005% to 1% by weight.

Powder formulations, granule formulations, and the like are typically used without dilution.

The present invention will be further described in detail by way of the formulation examples and test examples. However, the invention is not limited by the following examples.

In the following examples, "parts" means "parts by weight" unless otherwise provided.

Matching example 1

One of "formamide compounds" (1) to (5) (2.5 parts), ethaboxam (1.25 parts), polyoxyethylene styryl phenyl ether (14 parts), dodecylbenzene Calcium sulfonate (6 parts) and xylene (76.25 parts) were thoroughly mixed to separately produce each formulation.

Matching example 2

One of "meramide compound" (1) to (5) (2 parts), ethaboxam (8 parts), white carbon and polyoxyethylene alkyl ether ammonium sulfate by wet milling The mixture (weight ratio 1:1) (35 parts) and water (55 parts) were mixed and pulverized to produce respective formulations separately.

Matching example 3

Mixing one of "formamide compounds" (1) to (5) (5 parts), ethaboxam (10 parts), sorbitan trioleate (1.5 parts), and containing polyvinyl alcohol (2) An aqueous solution (28.5 parts) was pulverized by wet milling. An aqueous solution (45 parts) containing celestial gum (0.05 parts) and magnesium aluminum citrate (0.1 parts) was added to the pulverized mixture, and additional propylene glycol (10 parts) was added to the mixture. The resulting mixture was mixed by stirring to separately produce each formulation.

Matching example 4

One of "meramide compound" (1) to (5) (1 part), ethaboxam (4 parts), synthetic hydrated cerium oxide (1 part), calcium lignosulfonate (2 parts) Bentonite (30 parts) and kaolin (62 parts) were thoroughly mixed and ground. Water was added to the mixture, and the mixture was sufficiently kneaded, granulated, and then dried to separately produce each formulation.

Matching example 5

One of "formamide compounds" (1) to (5) (12.5 parts), ethaboxam (37.5 parts), calcium lignosulfonate (3 parts), sodium lauryl sulfate (2 parts) and The synthesized hydrated cerium oxide (45 parts) was thoroughly mixed and ground to separately produce each formulation.

Matching example 6

One of the "formamide compounds" (1) to (5) (3 parts), ethaboxam (2 parts), kaolin (85 parts) and talc (10 parts) thoroughly mixed and ground to separate Each formulation is produced.

Test examples using the respective "compositions" are shown below.

Test example 1

A cyclohexanone solution (100 μL) containing a predetermined amount (by weight) of the test compound was applied to soybean seeds using a rotary device for seed treatment (seed dresser, manufactured by Hans-Ulrich Hege GmbH) (variety: Natto shoryu) )(10 grams).

After one day of application, the plastic pots were filled with soil contaminated with Rhizoctonia solani, and the seeds treated with the test compound were sown in the soil and cultivated in a glass greenhouse for up to 20 days (hereinafter referred to as To "handle the land").

Thereafter, the presence of a disease caused by Rhizoctonia solani in seedlings germinated from various seeds was observed and the severity of the disease was calculated according to the following calculation formula (1).

On the other hand, soybean seeds which are not treated as described above (hereinafter referred to as "untreated land") are cultivated in the same manner as described above, and the disease severity in "untreated land" is calculated in the same manner as "processing of land" as described above.

According to the disease severity in the above-mentioned "treated land" and "untreated land", the effect in "treating land" is calculated according to the following formula (2).

The results are shown in Tables 1 and 2.

Calculation formula (1):

Severity of disease (%) = (number of infected seedlings / total number of seedlings) × 100

Calculation formula (2):

Efficacy (%) = [1 - (Severity of disease in "treated land" / severity of disease in "untreated land")] × 100

[Industrial Applicability]

A plant disease control composition comprising a "methionine compound" represented by the formula (I) and a thiazolid can be used for the prevention of plant diseases.

Claims (5)

A plant disease control composition comprising a formamide compound represented by the formula (1): And ethaboxam (ethaboxam). The plant disease control composition according to claim 1, wherein the weight ratio of the formamide compound to the ethaboxam is from 0.1/1 to 10/1. A method for controlling plant diseases, comprising the step of treating a plant or a soil of a growing plant with an effective amount of a methotrexate compound and ethaboxam, wherein the formamide compound is represented by the formula (1): The method for controlling plant diseases according to the third aspect of the patent application, wherein the weight ratio of the formamide compound to the ethaboxam is from 0.1/1 to 10/1 by the form of the carbamide compound/the ethaboxam. A method for controlling plant diseases according to claim 3 or 4, wherein the soil of the plant or the growing plant is soybean or soil for growing soybeans, respectively.