TWI496566B - 人工腦膜醫療裝置 - Google Patents

人工腦膜醫療裝置 Download PDF

Info

Publication number
TWI496566B
TWI496566B TW098145754A TW98145754A TWI496566B TW I496566 B TWI496566 B TW I496566B TW 098145754 A TW098145754 A TW 098145754A TW 98145754 A TW98145754 A TW 98145754A TW I496566 B TWI496566 B TW I496566B
Authority
TW
Taiwan
Prior art keywords
artificial
skull
meningeal
meninges
medical device
Prior art date
Application number
TW098145754A
Other languages
English (en)
Other versions
TW201029636A (en
Inventor
Chun Jen Liao
Sheng Hong Tseng
Huang Chien Liang
Chun Hung Chen
yi chun Su
Original Assignee
Ind Tech Res Inst
Univ Nat Taiwan Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Tech Res Inst, Univ Nat Taiwan Hospital filed Critical Ind Tech Res Inst
Publication of TW201029636A publication Critical patent/TW201029636A/zh
Application granted granted Critical
Publication of TWI496566B publication Critical patent/TWI496566B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2875—Skull or cranium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/688—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin for reattaching pieces of the skull
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2846—Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30907—Nets or sleeves applied to surface of prostheses or in cement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2846—Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
    • A61F2002/285—Fixation appliances for attaching bone substitute support means to underlying bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30433—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels, rivets or washers e.g. connecting screws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30448—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30462—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements retained or tied with a rope, string, thread, wire or cable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0041—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels or rivets, e.g. connecting screws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/005—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3675—Nerve tissue, e.g. brain, spinal cord, nerves, dura mater

Landscapes

  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Description

人工腦膜醫療裝置
本發明係有關於一種人工腦膜醫療裝置。
操作腦神經外科手術時，須將頭骨切開並且破壞腦膜才可進行，手術結束後，外科醫師會使用腦膜替代品修復受損之腦膜。在臨床上，已有多種自然或合成的腦膜替代物，例如自體移植物(autografts)、異體移植物(allografts)、異種移植物(xenografts)以及不可吸收以及可吸收的高分子(absorbable or unabsorbable polymers)等。而這些腦膜替代物最主要的功能包括避免引發感染及不良的組織反應、有效防止腦脊液滲漏、促進硬腦膜組織再生、防止腦組織沾黏。
腦膜修復方法包括需縫合方法以及免縫合方法，自體移植物(autografts)、異體移植物(allografts)、異種移植物(xenografts)以及不可吸收的高分子(例如Neuro-Patch)屬於傳統需縫合的方法。在臨床上常遇到的缺點包括手術時間長以及操作便利性差，以至於在操作上增加了風險，為解決腦膜修補的臨床需求，因此目前已有不需縫合的簡易操作，例如DuraGen(Integra)，以提供較短的操作時間以及較佳的操作便利性，因此可降低手術風險，故免縫合方法使用率較高。
最常使用的人工腦膜為以膠原(collagen)為材料的DuraGen，手術之步驟僅需將DuraGen剪裁成較受損腦膜 為大的面積，並且將DuraGen人工腦膜覆蓋於受損腦膜上，即完成手術，然而，免縫合方法的固定性差，因此容易造成人工腦膜之位移且腦脊髓液容易滲漏。
本發明提供一種人工腦膜醫療裝置，人工腦膜醫療裝置用來與由患者之整個頭骨上裁切下來之部份頭骨，包括人工腦膜以及連接元件，連接元件與具有人工腦膜之部份頭骨固定其中，該部份頭骨包括側表面以及內表面，且該人工腦膜覆蓋該部份頭骨之整個該內表面，當該部份頭骨以及該人工腦膜固定於該整個頭骨之上時，該部份頭骨之該內表面朝向於該患者的腦。
應注意的是，連接元件於內表面將人工腦膜固定。
應注意的是，連接元件包括綑綁件、螺絲、鉤體、膠體或固定釘。
應注意的是，連接元件於外表面將人工腦膜固定。
應注意的是，連接元件包括綑綁件、螺絲、鉤體、膠體或固定釘。
應注意的是，部份頭骨包括複數孔洞，人工腦膜覆蓋部份頭骨之內表面，且藉連接元件通過孔洞以於外表面固定人工腦膜。
應注意的是，連接元件包括縫合線。
應注意的是，連接元件設置於部份頭骨以及人工腦膜 之間。
應注意的是，連接元件包括二勾持部，分別插入部份頭骨以及人工腦膜。
應注意的是，連接元件包括基部、第一嵌合部以及第二嵌合部，第一嵌合部以及第二嵌合部設於基部之二對應表面，第一嵌合部被插入部份頭骨中，且第二嵌合部被插入人工腦膜中。
應注意的是，連接元件包括膠體。
應注意的是，連接元件包括複數凸出部以及複數溝槽，凸出部設於人工腦膜上，且溝槽設於部份頭骨上，凸出部與溝槽嵌合。
應注意的是，人工腦膜醫療裝置更包括複數襯墊以及複數環體，其中襯墊設於環體上，環體固定人工腦膜以及部份頭骨，襯墊設於連接元件以及人工腦膜之間以增加摩擦力。
第1圖為部分頭骨之示意圖，該部份頭骨由整個頭骨上裁切出來。第2圖為部分頭骨與人工腦膜醫療裝置結合之一實施例之示意圖。第3圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。第4圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。第5圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。第6圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例 之示意圖。
請參閱第1、2圖，操作腦神經外科手術時，醫生由整個頭骨10上裁切部份頭骨11，而整個頭骨10底下之腦膜同時遭到破壞，並且，於整個頭骨10上形成一裁切孔12。在醫生修復腦神經後，受損的腦膜也必須被修復，接著，部份頭骨11才能覆蓋於裁切孔12上，因此，本發明提供一種人工腦膜醫療裝置。人工腦膜醫療裝置20包括人工腦膜21以及連接元件22a，連接元件22a與具有人工腦膜21之部分頭骨11固定，部份頭骨11包括外表面111、內表面以及側表面112，請參閱第2圖，本實施例之人工腦膜21覆蓋部份頭骨11之內表面、側表面112以及部分之外表面111，且連接元件22a將人工腦膜21固定於側表面112上，於本實施例中，連接元件22a為綑綁件，以綑綁人工腦膜21以及部份頭骨11。連接元件22a更可為螺絲、鉤體、鉚釘、膠體或固定釘，但不限於以上揭露之實施態樣。
請參閱第3、4圖，第3、4圖之結構大致同於第2圖之實施例，相同元件省略不再贅述。而主要差異處在於連接元件22a於外表面111固定人工腦膜21，在第3、4圖之實施例中，連接元件22a更可為螺絲、鉤體、鉚釘、膠體或固定釘，但不限於以上揭露之實施態樣。
請參閱第5圖，第5圖之結構大致同於第3圖之實施例，相同元件省略不再贅述。而主要差異處在於人工腦膜醫療裝置20更包括襯墊23，襯墊23設於連接元件22a以及人工腦膜21之間以增加摩擦力。
請參閱第6圖，第6圖之結構大致同於第5圖之實施 例，相同元件省略不再贅述。而主要差異處在於人工腦膜醫療裝置20更包括複數襯墊23以及一環體24，襯墊23設於環體24上，環體24固定人工腦膜21以及部份頭骨11，接著，連接元件22a通過襯墊23將人工腦膜21固定於部份頭骨11上，襯墊23設於連接元件22a以及人工腦膜21之間以增加摩擦力。
第7圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。第8圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。
請參閱第7圖，人工腦膜醫療裝置20包括人工腦膜21以及連接元件22a，部份頭骨11更包括複數孔洞113，使醫生更為輕易地由整個頭骨10上取下部份頭骨11(如第1圖所示)。人工腦膜21包括四個延伸部212，且人工腦膜21覆蓋部份頭骨11並且藉由連接元件22a以及延伸部212將人工腦膜21固定於側表面112上。於本實施例中，連接元件22a為螺絲，而連接元件22a更可為膠體(未圖示)，但不限於以上揭露之實施態樣。
請參閱第8圖，人工腦膜醫療裝置20包括人工腦膜21以及連接元件22a，人工腦膜21覆蓋部份頭骨11並且藉由連接元件22a於外表面111將人工腦膜21固定於部份頭骨11之上。於本實施例中，連接元件22a為鉤體，而連接元件22a更可為膠體(未圖示)，但不限於以上揭露之實施態樣。在部份頭骨11與人工腦膜21結合後，部份頭骨11以及人工腦膜21被一起放置於整個頭骨10上的裁切孔12中並將其填滿。
第9圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。請參閱第9圖，部份頭骨11更包括複數孔洞113，而連接元件22a為縫合線，縫合線可掛起人工腦膜21，並且使縫合線穿過孔洞113將人工腦膜21與部份頭骨11固定。
第10圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。第11圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。
請參閱第10圖，連接元件22b被設於部份頭骨11與人工腦膜21之間，連接元件22b包括二勾持部221b、222b，其分別水平地插入部份頭骨11與人工腦膜21中。
請參閱第11圖，連接元件22b包括基部221c、第一嵌合部222c以及第二嵌合部223c，第一嵌合部222c以及第二嵌合部223c設於基部221c之二對應表面224c、225c。第一嵌合部222c被插入部份頭骨11中，且第二嵌合部223c被插入人工腦膜21中。
第12圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。請參閱第12圖，部份頭骨11包括複數溝槽114，於本實施例中，人工腦膜22d之初始狀態為液態，因此，液態人工腦膜22d被灌至部份頭骨11並且填滿溝槽114。由於材料特性，液態人工腦膜22d會轉變成膠態或固態而變成複數凸出部211a，因此，人工腦膜21可與部份頭骨11黏著且藉由凸出部211a與部份頭骨11嵌合。應注意的是，凸出部211a以及溝槽114為楔形態樣，而人工腦膜22d之初始狀態為液態。
第13圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖。人工腦膜醫療裝置20包括人工腦膜21以及二連接元件22e，連接元件22e包括複數凸出部211b以及複數溝槽114，凸出部211b與溝槽114嵌合，以將部份頭骨11與人工腦膜21固定。於本實施例中，凸出部211b與人工腦膜21為一體成形之單一元件，溝槽114設於部份頭骨11上，應注意的是，凸出部211b以及溝槽114為楔形態樣。
第14圖為使用本發明之人工腦膜醫療裝置之腦部手術方法流程圖之一實施例。請搭配參閱第1、2、14圖，其步驟包括：a.由整個頭骨10上裁切部份頭骨11；b.將人工腦膜21與部份頭骨11固定；c.將與人工腦膜21固定之部份頭骨11固定於整個頭骨10上之裁切孔12中。應注意的是，人工腦膜21預先被裁切成適當的尺寸以及厚度，在步驟b.中，人工腦膜21藉由連接元件22a、22b、22c、22e而與部份頭骨11固定(第2-8、10、11、13圖)。或者，人工腦膜21藉由由液態人工腦膜22d製成之凸出部211a嵌合溝槽114，達成與部份頭骨11之固定(請參閱第12圖)。
第15圖為使用本發明之人工腦膜醫療裝置之腦部手術方法流程圖之另一實施例。請搭配參閱第1、9、15圖，其步驟包括：a1.由整個頭骨10上裁切部份頭骨11；b1.在部份頭骨11上鑽設一開孔113；c1.使人工腦膜21穿過開孔113以覆蓋部份頭骨11；d1.藉由一固定元件22使人工腦膜21與部份頭骨11固定；e1.將與人工腦膜21固定之部份頭 骨11固定於整個頭骨10上之裁切孔12中。
綜上所述，本發明可避免將人工腦膜21在腦部組織上與缺損之腦膜直接縫合，可降低腦部手術之風險以及減少手術時間，再者，固定於部份頭骨11上之人工腦膜21可藉由與整個頭骨10嵌合之方式，穩定地覆蓋缺損之腦膜，以避免腦脊髓液滲漏。換言之，在本發明之實施例中，該人工腦膜與缺損之腦膜組織在空間上不共面，且該人工腦膜穩定地覆蓋缺損之腦膜。
惟以上所述者，僅為本發明之較佳實施例而已，當不能以此限定本發明實施之範圍，即大凡依本發明申請專利範圍及發明說明內容所作之簡單的等效變化與修飾，皆仍屬本發明專利涵蓋之範圍內。另外本發明的任一實施例或申請專利範圍不須達成本發明所揭露之全部目的或優點或特點。此外，摘要部分和標題僅是用來輔助專利文件搜尋之用，並非用來限制本發明之權利範圍。
 本發明
10‧‧‧整個頭骨
11‧‧‧部份頭骨
111‧‧‧外表面
112‧‧‧側表面
113‧‧‧孔洞
114‧‧‧溝槽
12‧‧‧裁切孔
20‧‧‧人工腦膜醫療裝置
21‧‧‧人工腦膜
211a、211b‧‧‧凸出部
212‧‧‧延伸部
22a、22b、22d、22e‧‧‧連接元件
221b、222b‧‧‧勾持部
221c‧‧‧基部
222c‧‧‧第一嵌合部
223c‧‧‧第二嵌合部
224c、225c‧‧‧對應表面
23‧‧‧襯墊
24‧‧‧環體
第1圖為部分頭骨之示意圖，該部份頭骨由整個頭骨上裁切出來；第2圖為部分頭骨與人工腦膜醫療裝置結合之一實施例之示意圖；第3圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第4圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第5圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第6圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第7圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第8圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第9圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第10圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第11圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第12圖為部分頭骨與人工腦膜醫療裝置結合之另一 實施例之示意圖；第13圖為部分頭骨與人工腦膜醫療裝置結合之另一實施例之示意圖；第14圖為使用本發明之人工腦膜醫療裝置之腦部手術方法流程圖之一實施例；以及第15圖為使用本發明之人工腦膜醫療裝置之腦部手術方法流程圖之另一實施例。
11‧‧‧部份頭骨
114‧‧‧溝槽
21‧‧‧人工腦膜
211a‧‧‧凸出部
22d‧‧‧連接元件

Claims (13)

  1. 一種人工腦膜醫療裝置，用於修補因為從一患者之一整個頭骨上裁切下來一部份頭骨而受損的腦膜組織，該部份頭骨被取下後，一裁切孔形成於該整個頭骨，包括：一人工腦膜；以及一連接元件，將該人工腦膜固定於該部份頭骨，其中，該部份頭骨包括一側表面以及一內表面，且該人工腦膜覆蓋該部份頭骨之整個該內表面，其中，當該部份頭骨以及該人工腦膜置入該裁切孔並固定於該整個頭骨之上時，該部份頭骨之該內表面朝向於該患者的腦，該人工腦膜與該受損的腦膜組織不共面，且該人工腦膜覆蓋該受損的腦膜組織，藉此，該受損的腦膜組織被該人工腦膜所修復，而毋須將該人工腦膜縫合於該受損的腦膜組織。
  2. 如申請專利範圍第1項所述之人工腦膜醫療裝置，其中，該連接元件於該側表面將該人工腦膜固定。
  3. 如申請專利範圍第2項所述之人工腦膜醫療裝置，其中該連接元件包括一綑綁件、一螺絲、一鉤體、一膠體或一固定釘。
  4. 如申請專利範圍第1項所述之人工腦膜醫療裝置，其中，該連接元件於該外表面將該人工腦膜固定。
  5. 如申請專利範圍第4項所述之人工腦膜醫療裝置，其中該連接元件包括一綑綁件、一螺絲、一鉤體、一膠體或一固定釘。
  6. 如申請專利範圍第4項所述之人工腦膜醫療裝置，其中該部份頭骨包括複數孔洞，該人工腦膜覆蓋該部份頭骨之該內表面，該連接元件通過該等孔洞以於該外表面將該人工腦膜固定。
  7. 如申請專利範圍第6項所述之人工腦膜醫療裝置，其中該連接元件包括一縫合線。
  8. 如申請專利範圍第1項所述之人工腦膜醫療裝置，其中該連接元件設置於該部份頭骨以及該人工腦膜之間。
  9. 如申請專利範圍第8項所述之人工腦膜醫療裝置，其中該連接元件包括二勾持部，分別插入該部份頭骨以及該人工腦膜。
  10. 如申請專利範圍第8項所述之人工腦膜醫療裝置，其中該連接元件包括一基部、一第一嵌合部以及一第二嵌合部，該第一嵌合部以及該第二嵌合部設於該基部之二對應表面，該第一嵌合部被插入該部份頭骨中，且該第二嵌合部被插入該人工腦膜中。
  11. 如申請專利範圍第8項所述之人工腦膜醫療裝置，其中該連接元件包括一膠體。
  12. 如申請專利範圍第1項所述之人工腦膜醫療裝置，其中該連接元件包括複數凸出部以及複數溝槽，該等凸出部設於該人工腦膜上，且該等溝槽設於該部份頭骨上，該等凸出部與該等溝槽嵌合。
  13. 如申請專利範圍第1項所述之人工腦膜醫療裝置，其更包括複數襯墊以及一環體，其中該等襯墊設於該環體 上，該環體固定該人工腦膜以及該部份頭骨，該等襯墊設於該連接元件以及該人工腦膜之間以增加摩擦力。
TW098145754A 2008-12-30 2009-12-30 人工腦膜醫療裝置 TWI496566B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14161008P 2008-12-30 2008-12-30

Publications (2)

Publication Number Publication Date
TW201029636A TW201029636A (en) 2010-08-16
TWI496566B true TWI496566B (zh) 2015-08-21

Family

ID=42285887

Family Applications (1)

Application Number Title Priority Date Filing Date
TW098145754A TWI496566B (zh) 2008-12-30 2009-12-30 人工腦膜醫療裝置

Country Status (2)

Country Link
US (2) US20100168871A1 (zh)
TW (1) TWI496566B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20095084A0 (fi) * 2009-01-30 2009-01-30 Pekka Vallittu Komposiitti ja sen käyttö
KR101567003B1 (ko) * 2013-12-27 2015-11-06 경희대학교 산학협력단 골편 고정장치 및 골편 절단을 위한 드릴 어셈블리
CA2958570C (en) * 2014-08-20 2017-11-28 Synaptive Medical (Barbados) Inc. Intra-operative determination of dimensions for fabrication of artificial bone flap
US20160331539A1 (en) * 2015-05-12 2016-11-17 Elwha Llc Modifiable implants
US12076244B1 (en) * 2020-09-30 2024-09-03 Aubrey Clinton Folsom Implantable cranial closure device and system with a sonic window and access port
US11806222B2 (en) * 2021-08-06 2023-11-07 John Baeke Apparatus for cutting a material and a method for cutting a negative pressure wound therapy dressing
CN113598872B (zh) * 2021-09-03 2023-06-09 苏州景昱医疗器械有限公司 一种颅骨开槽工具

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400833A (en) * 1981-06-10 1983-08-30 Kurland Kenneth Z Means and method of implanting bioprosthetics
US5503164A (en) * 1994-01-28 1996-04-02 Osteogenics, Inc. Device and method for repair of craniomaxillofacial bone defects including burr holes
US6350284B1 (en) * 1998-09-14 2002-02-26 Bionx Implants, Oy Bioabsorbable, layered composite material for guided bone tissue regeneration
US20070173844A1 (en) * 2006-01-17 2007-07-26 Ralph James D Craniotomy closures and plugs
US20070270974A1 (en) * 2001-03-02 2007-11-22 Woodwelding Ag Implants for creating connections to tissue parts, in particular to skeletal parts, as well as device and method for implantation thereof
EP1537883B1 (en) * 2003-12-05 2008-04-23 DePuy Mitek, Inc. Implants comprising viable tissue for repairing a tissue injury or defect

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3863345A (en) * 1971-12-30 1975-02-04 Oscar Malmin Endodontic sealing system and apparatus
US7351249B2 (en) * 1998-11-06 2008-04-01 Neomend, Inc. Systems, methods, and compositions for achieving closure of suture sites
US8460346B2 (en) * 2006-01-17 2013-06-11 Biodynamics Llc Craniotomy closures
US20080027442A1 (en) * 2006-07-25 2008-01-31 James Blue Cranial fixation device and method for fixing same
US20090259263A1 (en) * 2008-04-11 2009-10-15 Biomet Microfixation, Inc. Apparatus and methods of fixating bone
US8241336B2 (en) * 2008-10-10 2012-08-14 Z&R Medical, L.L.C. Craniotomy closure systems

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400833A (en) * 1981-06-10 1983-08-30 Kurland Kenneth Z Means and method of implanting bioprosthetics
US5503164A (en) * 1994-01-28 1996-04-02 Osteogenics, Inc. Device and method for repair of craniomaxillofacial bone defects including burr holes
US6350284B1 (en) * 1998-09-14 2002-02-26 Bionx Implants, Oy Bioabsorbable, layered composite material for guided bone tissue regeneration
US20070270974A1 (en) * 2001-03-02 2007-11-22 Woodwelding Ag Implants for creating connections to tissue parts, in particular to skeletal parts, as well as device and method for implantation thereof
EP1537883B1 (en) * 2003-12-05 2008-04-23 DePuy Mitek, Inc. Implants comprising viable tissue for repairing a tissue injury or defect
US20070173844A1 (en) * 2006-01-17 2007-07-26 Ralph James D Craniotomy closures and plugs

Also Published As

Publication number Publication date
US8986394B2 (en) 2015-03-24
TW201029636A (en) 2010-08-16
US20100168871A1 (en) 2010-07-01
US20120215322A1 (en) 2012-08-23

Similar Documents

Publication Publication Date Title
TWI496566B (zh) 人工腦膜醫療裝置
Masuoka et al. Stitched sling retraction technique for microvascular decompression: procedures and techniques based on an anatomical viewpoint
Caro-Osorio et al. Cranioplasty with polymethylmethacrylate prostheses fabricated by hand using original bone flaps: Technical note and surgical outcomes
EP2298225A3 (en) Arrangement and device for using a template to form holes for implants in bone, preferably jaw bone
Chauvet et al. Study of dural suture watertightness: an in vitro comparison of different sealants
RU2512782C1 (ru) Способ хирургического лечения назальной ликвореи
US20090248065A1 (en) Hemostatic device sealing damaged site with vacuum
Heller et al. Anterolateral thigh fasciocutaneous flap for simultaneous reconstruction of refractory scalp and dural defects: Report of two cases
KR20080037611A (ko) 디스크 임플랜트 장치
Nagel et al. Durotomy surrogate and seals for intradural spinal cord stimulators: apparatus and review of clinical methods and materials
JP2016202468A (ja) 頭蓋骨穿孔補填材
US20230310168A1 (en) Dural repair device and method of use
Ikawa Surgery of middle cerebral artery (mca) aneurysm
Rowe et al. Reconstruction of the base of skull defect—lessons learned over 25 combined years
KR101027331B1 (ko) 치조골 재생 장치
Pinzer et al. A complex therapy for treatment of frontoethmoidal meningoencephalocele in a developing third world country: neurosurgical aspects
Choudhari 'In-lay'duraplasty: a useful method of effective dural closure
JP2002253564A (ja) 補綴挿入物用セメントデフレクタおよび該デフレクタを用いて補綴移植を行う要素一式
RU2701910C1 (ru) Способ пластики дефекта твёрдой мозговой оболочки и герметизации субдурального пространства в области костного дефекта свода черепа
IT201900011313A1 (it) Kit di presidi chirurgici ortopedici per la realizzazione di un impianto di protesi di femore cementata.
I. OGUNGBO et al. A technique for dural repair following retromastoid suboccipital craniectomy
Cheesman et al. Lateral Rhinotomy
Gianoli Surgery, Complication, Revisions
TWM463577U (zh) 骨板
Teramoto Cerebrospinal fluid leakage due to dural thinning after endoscopic pituitary tumor resection