TWI481708B - Electromagnetic wave irradiating device - Google Patents

Description

Electromagnetic wave irradiation device

The present invention relates to an electromagnetic wave irradiation device, and more particularly to an electromagnetic wave irradiation device that irradiates electromagnetic waves to biological or biochemical substances.

In the biological and medical fields, the application of photoexcitation technology is quite extensive, involving not only the observation of experimental results, but also the regulation of protein activity and the stimulation of pharmaceutical ingredients, etc., which has extremely high practical value.

Photoexcitation is a special means of controlling matter or chemical reaction in addition to the energy of light. Although it is called photoexcitation, the range of light energy provided is not limited to visible light, but includes electromagnetic waves of various wavelengths. In terms of mechanism, light excitation is the use of the energy of the electromagnetic wave itself. When the electromagnetic wave is radiated onto the material, the energy carried by the electromagnetic wave is simultaneously input, causing the substance to activate and produce a reaction that cannot be performed.

In the second half of the twentieth century, photoexcitation technology has been widely used in various aspects of biology and medicine. For example, the electrophoresis technology used in general laboratories is to use ultraviolet light to stimulate the chemical embedded in deoxyribonucleic acid (DNA). The substance is allowed to emit fluorescence to allow the researchers to observe the size of the DNA fragment. In the advanced aspect, the application of green fluorescence protein (GFP) can be taken as an example. It combines the characteristics of gene transfer and photoexcitation to effectively enhance the ability to analyze protein expression and cytology.

In recent years, genetic engineering has rapidly entered the biomedical market due to the combination of light excitation. Technology can meet more stringent specificity requirements, making integrated light excitation regulation a key design for a variety of emerging products, especially in genetic engineering and drug activation. In order to avoid side effects and accidental injury to normal tissue, medical theory has long been the concept of target treatment. Simple explanation means that the drug does not immediately produce medicinal properties when it enters the human body, but is activated only after it reaches the affected part. This will reduce the impact on healthy tissue, where photoexcitation technology can play an important role in activating drugs. By utilizing the characteristics of electromagnetic wave penetration, medical personnel can easily manipulate drugs and activate activities from outside the patient, which has excellent practical effects. Similarly, genetic engineering, which has the same specificity requirements as drug activation, also uses a large number of photoexcitation techniques, such as the use of external light sources to control the timing and location of photo-cleaving reagents, thereby accurately knocking out specific cells ( Knockout), and replacement and recombination.

However, the devices or devices currently used to perform the photoexcitation process generally lack applicability, mainly because of the integration of design and microscope, and are limited to the observation of the results. For other purposes, the simple platform with the lamp is often used, and the actual operation may be This adds extra processing procedures or processes, which is quite inconvenient. Moreover, the sample is often in an open environment during electromagnetic wave processing, which not only lacks isolation of the pollution source, but also has the risk of collision or splashing when manually loading or removing the sample, if the object of the photoexcitation treatment is a cell Or when organizing, it is more likely that the user's negligence causes the body part contaminated with microorganisms to touch the inside of the sample or the processing space, causing pollution that is difficult to eradicate, indirectly increasing the time and expenditure cost of the photoexcitation treatment.

In view of this, how to develop an electromagnetic wave irradiation function Electromagnetic wave irradiation device with low operation pollution rate has good applicability, and providing multi-purpose use has become one of the most important issues at present.

In view of the above problems, an object of the present invention is to provide an electromagnetic wave irradiation apparatus which can provide an electromagnetic wave irradiation function and has a low operational contamination rate, and which has good applicability and can be used for multi-purpose use.

In order to achieve the above object, an electromagnetic wave irradiation apparatus according to the present invention irradiates electromagnetic waves to biological or biochemical substances. The electromagnetic wave irradiation device includes a casing, at least one electromagnetic wave irradiation unit, and a carrying unit. The housing has a cavity. The electromagnetic wave irradiation unit is disposed on at least one side of the housing. The carrying unit is coupled to the housing and at least partially received in the cavity, and the carrying unit is movable relative to the housing such that the carrying unit has an open state and a closed state.

The electromagnetic wave irradiation apparatus of the present invention further includes a driving unit that is disposed in the cavity and drives the carrying unit to move relative to the housing.

Further, in the electromagnetic wave irradiation apparatus of the present invention, the carrying unit may further have a tray in which the tray is located in the closed state, and the carrying unit further has a heating element, and the heating element is disposed on the tray.

Furthermore, in the electromagnetic wave irradiation device of the present invention, the electromagnetic wave wavelength range which can be provided includes visible light, and/or ultraviolet light, and/or infrared light, and/or fluorescent light, and/or laser light and/or X-ray light, The electromagnetic wave irradiation unit has at least one light emitting diode, or a laser or a light tube. The range of light exposure and the dose of radiation can be controlled.

As described above, since the electromagnetic wave irradiation device according to the present invention is provided with an electromagnetic wave irradiation unit and a movable load bearing unit, the carrier unit can be used to carry and transport the sample of the biological or biochemical substance to be processed into the sealed electromagnetic wave irradiation during operation. Within the device, the required electromagnetic waves are provided to act to achieve the purpose of use. That is to say, in the process of conveying the sample by the carrying unit, the structural design of the invention can avoid the direct contact of the user's hand with the sample, and the risk of external pollution can be reduced. Furthermore, when the sample is placed in an electromagnetic wave irradiation device, it is in a closed and non-polluting environment. Under the cover of the casing, the maximum amount of electromagnetic wave energy can be retained by the refraction, reflection and nonlinear optical design. The area to be illuminated. Compared with the prior art, the electromagnetic wave irradiation apparatus of the present invention can provide an electromagnetic wave irradiation environment with a stable controllable dose and range, which has a closed and low-pollution property. In addition, when used in combination with a light-emitting diode, the present invention can provide electromagnetic waves of a customized wavelength according to the requirements of the sample, which not only satisfies the working conditions, but also avoids the sample being caused by the lack of specificity of the wavelength range. It has excellent side effects and therefore has excellent applicability.

The present invention mainly utilizes electromagnetic waves emitted from an electromagnetic wave irradiation unit to treat biological or biochemical substances placed in an electromagnetic wave irradiation device. According to this concept, the biological or biochemical substance to be treated by the electromagnetic wave irradiation apparatus of the present invention is not particularly limited, and may be any biological or biochemical substance or a combination thereof that requires electromagnetic wave irradiation to change properties or initiate a reaction. It should be noted that the property caused by the electromagnetic wave irradiation device of the device is The qualitative change or reaction may include any change in nature or reaction in the physiological, or biochemical, or physical or chemical domain, and is not limited to any particular one, and is not particularly limited to changes in properties or reactions that occur in the organism.

A person who undergoes a property change or reaction after being irradiated by electromagnetic waves is not necessarily a unit of a whole biological individual, and may be a part of a biological individual, such as a local tissue or an organ of a biological individual. Of course, in addition to the above-mentioned intact biological individual and part thereof, the organism referred to herein may further comprise a collection of other living organisms or living organisms that do not reach the level of the biological individual, such as but not limited to viruses, or Tissue cultured cells or tissues and organs obtained through tissue engineering. In detail, the biological individual suitable for the treatment by the electromagnetic wave irradiation apparatus of the present invention may be any eukaryotic organism or prokaryote, and is not particularly limited, and the source of the living organism described above is not particularly limited, and the obtained cells are cultured. For example, it may be those obtained by culturing natural cells, or those obtained by culturing the cell strain, or the above-mentioned artificially manipulated or the above-mentioned artificially manipulated and then cultured.

The source of the "biochemical" encompassed by the present invention may include any molecule, or composition or polymer, for biological or medical purposes. Therefore, the source of the biochemical substance is not limited to the biological individual, and may also include the biological body. For example, the person from the organism can be DNA, or RNA or protein; and the person from outside the organism can be the active ingredient or chemical composition of the drug. In addition, the biochemical substance may be a naturally occurring person, or a naturally modified natural artificial or artificial synthetic person, and is not particularly limited. However, it is particularly important to mention that the biochemical substance is preferably an object that can be excited by electromagnetic waves. A mass, such as a photoexcited dicing reagent, facilitates cooperation with the electromagnetic wave illuminating device of the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, an electromagnetic wave irradiation apparatus according to a preferred embodiment of the present invention will be described with reference to the accompanying drawings, wherein the same elements will be described with the same reference numerals.

1 is a schematic structural view of an electromagnetic wave irradiation apparatus in an open state according to a preferred embodiment of the present invention. Referring to FIG. 1, the electromagnetic wave irradiation apparatus 1 includes a casing 11, at least one electromagnetic wave irradiation unit 12, and a load bearing unit 13.

The housing 11 has a cavity A for receiving other units and components. The shape of the casing 11 is not particularly limited, but is designed according to the size and shape required for the electromagnetic wave irradiation device 1 of the present invention. If it is convenient to place, please refer to FIG. 1 in the present embodiment. The outer shape of the housing 11 is a rectangular parallelepiped. Further, the structure of the casing 11 is also not limited, and may be a single member or a plurality of members. As shown in FIG. 1 , in the present embodiment, the housing 11 is formed by combining an upper housing 111 and a lower housing 112 and a front cover 113. The front cover 113 is disposed at the front end of the housing 11 and has a front cover 113. The opening H is accommodated in the cavity A for the carrying unit 13. The material that can be used for the casing 11 is not particularly limited, and may be a casing 11 containing metal, alloy or plastic, which provides a good shielding effect and reduces electromagnetic waves from being emitted into the environment.

The electromagnetic wave irradiation unit 12 is disposed on at least one side of the casing 11. In the present embodiment, the electromagnetic wave irradiation unit 12 is simultaneously disposed on the upper and lower sides of the casing 11 to provide omnidirectional illumination of the sample. Of course, in addition to this setting method, other setting methods can be used without any particular limitation. For example, the electromagnetic wave irradiation unit 12 is separately provided on the upper side or the lower side of the casing 11, or the electromagnetic wave irradiation unit 12 is provided on each side surface of the casing 11 so as to surround the carrying unit 13. The electromagnetic wave irradiation unit 12 emits electromagnetic waves to the sample, and accordingly, according to the type of the selected electromagnetic wave irradiation unit 12, the electromagnetic wave irradiation device 1 can provide an electromagnetic wave range required for any operation, and the wavelength can cover any range on the spectrum, including visible light, And/or ultraviolet light, and/or infrared light, and/or fluorescent light, and/or laser and/or X-ray, and the like. The electromagnetic wave irradiation unit 12 may include a light emitting diode, a laser diode, or a lamp tube, or any combination of the two. Of course, any other component or module suitable for emitting electromagnetic waves can be used. It is only necessary to pay attention to whether the electromagnetic wave provided by the electromagnetic wave irradiation unit 12 can cooperate with the requirements of the biological or biochemical substance to be processed to select the appropriate intensity and wavelength for emission. By. In the present embodiment, the electromagnetic wave irradiation unit 12 is a complex light emitting diode.

Please refer to FIG. 1 and FIG. 2 at the same time, wherein FIG. 2 is a schematic diagram of the closed state of the carrying unit. The carrier unit 13 is combined with the housing 11 and at least partially received in the cavity A. In the present embodiment, the carrying unit 13 may have a first joint portion 131, and the housing 11 may have a second joint portion 114 that cooperates with the first joint portion 131. Therefore, the carrier unit 13 can be coupled to the housing 11 by the first coupling portion 131 and the second coupling portion 114 being engaged or fitted with each other, so that the carrier unit 13 can be moved relative to the housing 11, and the bearing unit 13 can be moved. It can have an open state (as shown in Figure 1) and a closed state (as shown in Figure 2). Of course, the snap fit or the fitting is designed so that the carrying unit 13 can be moved relative to the housing 11 , and other forms of bonding can also be implemented. The carrying unit 13 preferably moves relative to the housing 11 in a sliding manner, For this, the first joint portion 131 and the second joint portion 114 can be a slide rail, or a sliding slot, or a roller, or a ball or a roller, or any combination thereof. Referring to FIG. 1 and FIG. 3 simultaneously, in the embodiment, the first joint portion 131 is a convex rail, and the second joint portion 114 is a sliding slot.

Therefore, the electromagnetic wave irradiation device 1 transports the biological or biochemical substance to be treated into the casing 11 by the carrying unit 13 partially accommodated in the cavity A, and then the electromagnetic wave emitted by the electromagnetic wave irradiation unit 12 is biologically or biochemically The substance is irradiated to achieve the object of the present invention.

In addition, in order to further reduce the chance of the operator touching the pollution, in the embodiment, the carrying unit 13 is preferably opened and closed in a semi-automatic manner, for example, the user can press a button to input a signal to the electromagnetic wave irradiation device 1. The electromagnetic wave illuminating device 1 can drive the carrying unit 13 to move, and the carrying unit 13 can be automatically moved between the open state and the closed state without intervening by excessive external force. In order to achieve the above design, please refer to FIG. 1 and FIG. 4 , in the embodiment, the electromagnetic wave irradiation device 1 further includes an input module 14 and a driving unit 15 , wherein the input module 14 is disposed in the lower casing 112 . Above, the drive unit 15 is disposed in the cavity A of the housing 11. The input module 14 is electrically connected to the driving unit 15 , and the input module 14 has a switch button S. The driving unit 15 is connected to the carrying unit 13 through a transmission mechanism disposed in the housing 11 . Therefore, the semi-automatic operation mode of the carrying unit 13 is to input a signal to the input module 14 by the human touch switch button S, and the input module 14 transmits the signal to the driving unit 15, so that the driving unit 15 drives the carrying unit 13 to move relative to the housing 11. . As for the power source of the driving unit 15 driving the carrying unit 13, there is no use A particular limitation may be, for example but not limited to, a linear motor, or a stepper motor, or a brushed motor, or a brushless motor, or a combination thereof. In addition, the transmission mechanism of the driving unit 15 for connecting the carrying unit 13 may be a gear set, and/or a rotating shaft, and/or a rack, and/or a transmission belt and/or a combination thereof.

The above-mentioned semi-automatic mode is a preferred opening and closing mode of the carrying unit 13. However, the carrying unit 13 is not limited to the one opening and closing mode, and other opening and closing modes can also be used together. Referring to FIG. 3, in the present embodiment, the electromagnetic wave irradiation device 1 can also open and close the carrier unit 13 by manual means. To this end, the carrying unit 13 can have a baffle 133, and the baffle 133 can be further provided with a groove G suitable for applying force, which is used for applying force when the user manually opens and closes. The baffle 133 is disposed at the front end of the carrying unit 13 and is connected to the tray 132 so as to be perpendicular to each other for closing the opening H of the casing 11 in the closed state, so that a sealed and void-free space can be formed in the electromagnetic wave irradiation device 1. The space is conducive to electromagnetic wave irradiation. The structure and shape of the baffle 133 are not particularly limited, and it is preferable to match the housing 11 and the opening H, and the baffle 133 is preferably made of a resin material, which is light in weight and sufficient. The baffle 133 of the protective ability, of course, the baffle 133 may also be made of other materials such as metal or glass, and is not particularly limited in use. The groove G may be any structure that can assist in manual opening and closing, and is not particularly limited in use, and may be, for example but not limited to, a handle, or a handle or a pull ring.

In order to facilitate loading and transporting biological or biochemical substances into the electromagnetic wave irradiation device 1, please refer to FIG. 1 and FIG. 2 at the same time. In this embodiment, the carrying unit 13 may have a tray 132 when the tray 132 is in an open state. (shown in Figure 1), it may extend partially or wholly out of the cavity A of the housing 11, allowing the operator to place the biological or biochemical material to be treated on the tray 132. When in the closed state (as shown in FIG. 2), the tray 132 is located in the cavity A of the housing 11 for electromagnetic wave irradiation or other processing.

Referring to FIG. 1 and FIG. 3 simultaneously, in the embodiment, the carrying unit 13 can have a heating element 134 disposed on the tray 132. The heating element 134 is used as a heat source to raise the temperature in the cavity A. Or directly heat the whole or part of the biological or biochemical substance. The heating element 134 used as the heat source may be an indium tin oxide (ITO) layer, or a heating resistor wire or an electrothermal tube. Of course, other members that achieve the same purpose may be used. The manner in which the heating element 134 is disposed on the tray 132 is not particularly limited, and is mainly to match the type of the heating element 134 itself, and may be, for example, but not limited to, sputtering, or covering, or covering or inlaying. In order to achieve the maximum amount of electromagnetic wave receiving and heat treatment at the same time, please refer to FIG. 1 . In the embodiment, the heating element 134 is selected from an indium tin oxide layer, and the indium tin oxide is firstly sputtered. The method is applied to a glass 135 to form a heating element 134, and the indium tin oxide-coated glass 135 is embedded in the tray 132. Accordingly, the carrying unit 13 having the heating element 134 can not only effectively heat the biological or biochemical substance, but since the glass 135 and the indium tin oxide layer are transparent materials, the electromagnetic wave can penetrate the carrying unit 13 without being heated. The arrangement of the element 134 affects the processing effect of electromagnetic wave irradiation.

To control the heating element 134 to avoid the heating element 134 Excessively, causing adverse effects on biological or biochemical substances, or making the internal temperature of the electromagnetic wave irradiation device 1 too high, please refer to FIG. 1 , in the present embodiment, the electromagnetic wave irradiation device 1 further includes a temperature control unit 16 The heating element 134 and the input module 14 are electrically connected. The temperature control unit 16 can control the heating element 134 by the signal input from the input module 14, thereby adjusting the degree of heating of the biological or biochemical substance and the internal temperature of the electromagnetic wave irradiation apparatus 1. In this way, the biological or biochemical substance can be irradiated with electromagnetic waves at an appropriate operating temperature.

In addition, in order to make the electromagnetic wave irradiation unit 12 properly disposed on the housing 11 and easily replaceable, please refer to FIG. 1 . In the embodiment, the electromagnetic wave irradiation apparatus 1 further includes a frame 17 which is separately disposed. On the upper side and the lower side of the casing 11, the electromagnetic wave irradiation unit 12 is further disposed on the frame body 17. The frame body 17 can be any suitable for the user to cooperate with the housing 11 and the electromagnetic wave irradiation unit 12. The shape, or the structure or the material is not particularly limited. In the embodiment, the frame body 17 is made of metal. The groove-like structure is fixed to the upper casing 111 and the lower casing 112 in a locking manner.

Referring to FIG. 1 , in the embodiment, the electromagnetic wave irradiation device 1 further includes a control unit 18 disposed in the housing 11 and electrically connected to the electromagnetic wave irradiation unit 12 . The control unit 18 can turn on or off the electromagnetic wave irradiation unit 12 by transmitting a signal. In addition, referring to FIG. 1 , in the embodiment, the electromagnetic wave irradiation device 1 further includes a timing unit 19 disposed in the housing 11 , and the timing unit 19 is respectively connected to the input module 14 and the temperature control. The unit 16 and the control unit 18 are electrically connected. user As long as the target temperature and the target irradiation time are input to the input module 14, the temperature control unit 16 can control the heating element 134 to start heating to raise the temperature in the cavity A. When the temperature rises to the target temperature, the control unit 18 can control the electromagnetic wave irradiation unit 12 to emit electromagnetic waves to the sample. The timing unit 19 starts counting, and when the target irradiation time is reached, a signal is sent to the control unit 18 to turn off the electromagnetic wave of the electromagnetic wave irradiation unit 12. It should be noted that heating and electromagnetic wave irradiation may also be performed separately, and the first heating or the first electromagnetic wave irradiation may be implemented by the device. In addition, the timing unit 19 can also be used as a time count for maintaining the temperature of the cavity.

Referring to FIG. 4 , in the embodiment, the electromagnetic wave irradiation device 1 further includes a display module M disposed on the front cover 113 of the housing 11 , and the display module M and the input module 14 . The timing unit 19 and the temperature control unit 16 are electrically connected to display the time and temperature setting of the input of the input module 14 by human power, and the temperature of the heating element 134 and/or the internal temperature of the electromagnetic wave irradiation device 1 can be immediately displayed. In addition, the display module M can receive the signal sent by the timing unit 19 during the countdown time, and instantly display the history of the countdown time.

In addition, the electromagnetic wave irradiation device 1 may further include a filter element (not shown) disposed in the housing 11 and disposed in cooperation with the electromagnetic wave irradiation unit 12, and the electromagnetic wave irradiation unit 12 may be changed by providing different filter elements. The wavelength of the biological or biochemical substance is irradiated, so that the electromagnetic wave wavelength can be adjusted according to the user's needs without resetting the electromagnetic wave irradiation unit 12.

Based on the foregoing, it can be seen that the electromagnetic wave irradiation device of the present invention has a phase When the scope is widely applied, for example, but not limited to, genetic engineering, or pharmacological activation, or protein regulation, or cultivation of algae and fungi or laser tattoos of living organisms. Of course, other objects that can be achieved by using the present invention are also applicable to the electromagnetic wave irradiation apparatus of the present invention. The above application range will be further exemplified in detail below.

When using the present invention in genetic engineering, the electromagnetic wave irradiation device of the present invention can be mainly used in combination with various known substances that can be excited by electromagnetic waves, such as photoexcited nucleic acid cleavage reagents, such as arylhydrazone. The nucleic acid cleavage reagent does not act on nucleic acids under normal conditions and must be excited by electromagnetic waves of a suitable wavelength. In operation, first, a DNA molecule or a plasmid to be subjected to nucleic acid cleavage is mixed with a composition containing aryl benzaldehyde, and then placed in an electromagnetic wave irradiation device equipped with a light-emitting diode, and the inside of the unit is illuminated by electromagnetic waves. The blue light emitted by the diode (having a wavelength of about 460 nm) illuminates the composition, and the heating element provides a suitable temperature for activation of the aryl benzaldehyde component in the composition to complete the cutting of the DNA molecule or plastid. .

The object suitable for activation by the electromagnetic wave irradiation device may be, for example, a nucleoside-containing pharmaceutical composition, which is a pharmaceutically acceptable substance 5-fluorouracil (5-FU) as a pharmaceutical active ingredient. Spherical nanoparticles coated with an oligonucleotide molecule (oligonucleotide) were used as a carrier. In the general case, nucleosides are tightly confined to the carrier due to binding to the oligonucleotide chain, in an inactive state. When a cancer cell (for example, an oral cancer or a large intestine cancer cell) is placed together with the above-mentioned pharmaceutical composition in an electromagnetic wave irradiation device, as a carrier The body's nanoparticle penetrates the cell membrane and enters the cancer cell, and carries 5-fluorouracil together. Thereafter, the electromagnetic wave emitted by the electromagnetic wave irradiation unit (wavelength is 535 nm) can make the surface of the nanoparticle surface surface-electric. The surface plasma resonance effect causes the carrier to release 5-fluorouracil for the purpose of inhibiting or destroying the target cancer cells. When a long strip of nano carrier is used to carry the drug, the electromagnetic wave can be changed to use an electromagnetic wave having a wavelength of 800 nm.

In terms of protein regulation, cells transfected with green fluorescent protein can be placed into an electromagnetic wave irradiation device, and an appropriate wavelength emitted by the electromagnetic wave irradiation device can excite the nucleic acid to cleave, resulting in a decrease in the performance of the green fluorescent protein, thereby emitting green fluorescent light. The strength can be observed as a basis for technical improvement.

In addition, since the electromagnetic wave irradiation device can have a function of maintaining a certain temperature in the cavity, it can also be used as an incubator for bacteria, algae or microorganisms, and only the fungi, algae or microorganisms need to be placed in the medium or the culture solution. After being placed in the cavity, the electromagnetic wave irradiation device can be used to provide a wavelength and a culture temperature suitable for the growth of bacteria, algae or microorganisms to accelerate the growth of bacteria, algae or microorganisms. Moreover, in combination with different growth periods, the electromagnetic wave irradiation unit can also change different electromagnetic wave wavelengths or culture temperatures so that the fungi, algae or microorganisms can grow under optimal conditions. Of course, in addition to the growth of the batch, if the line circulation equipment can be combined to transport bacteria, algae or microorganisms, the electromagnetic wave irradiation apparatus can also be continuously cultured.

Furthermore, the electromagnetic wave irradiation device of the present invention can also replace the traditional imprinting technology, and the laser tattoo of animals or plants, especially for the use of tattoos of poultry livestock or pets, can help alleviate the pain of the animals themselves. Skin damage. For example, a common mouse can be placed in the electromagnetic wave irradiation device of the present invention, and the electromagnetic wave having the ability to penetrate the epidermal cells emitted by the electromagnetic wave irradiation unit can be used, and a suitable mask can be used to transfer the planned pattern. Fastens and effectively achieves the purpose of tattooing on the skin of poultry or pets.

As described above, the electromagnetic wave irradiation apparatus of the present invention can provide electromagnetic waves of an arbitrary range or a specific wavelength by the electromagnetic wave irradiation unit, and thus can be widely applied to various biological and medical purposes, and has good applicability. In addition, the use of the semi-automatic load-bearing unit helps to reduce the probability of direct contact of biological sources with biological or biochemical substances during operation, and enhance the safety of light excitation or electromagnetic wave processing procedures. In addition, the housing of the electromagnetic wave irradiation device properly covers the sample, the electromagnetic wave emitting source and the heating element in the same space, which not only further reduces the pollution, maintains the constant temperature internal working environment, but also uses the housing to transmit electromagnetic waves. It is kept in the electromagnetic wave irradiation device to avoid waste of energy due to scattering of electromagnetic waves into the environment. Furthermore, the timing unit provided by the electromagnetic wave irradiation device of the present invention can actively control the duration of electromagnetic wave irradiation and heating according to the setting, thereby saving labor cost and accurately controlling the flow of the light excitation step. If used in conjunction with a filter element, the wavelength of the exposure to the biological or biochemical substance can be adjusted in a simple manner by adding a filter to suit different application objects.

The above is intended to be illustrative only and not limiting. Any equivalent modifications or alterations to the spirit and scope of the invention are intended to be included in the scope of the appended claims.

1‧‧‧Electromagnetic wave irradiation device

11‧‧‧Shell

111‧‧‧Upper casing

112‧‧‧ Lower case

113‧‧‧ front cover

114‧‧‧Second junction

12‧‧‧Electromagnetic wave irradiation unit

13‧‧‧Loading unit

131‧‧‧ First Joint Department

132‧‧‧Tray

133‧‧ ‧Baffle

134‧‧‧ heating element

135‧‧‧ glass

14‧‧‧Input module

15‧‧‧Drive unit

16‧‧‧ Temperature Control Unit

17‧‧‧ ‧ body

18‧‧‧Control unit

19‧‧‧Time unit

A‧‧‧cavity

G‧‧‧ Groove

H‧‧‧ openings

M‧‧‧ display module

S‧‧‧ switch button

1 is a schematic view showing the internal structure of an electromagnetic wave irradiation device in an open state according to a preferred embodiment of the present invention; FIG. 2 is a schematic view showing a closed state of an electromagnetic wave irradiation device according to a preferred embodiment of the present invention; FIG. 3 is a carrier unit and a casing of FIG. FIG. 4 is a front perspective view of an electromagnetic wave irradiation apparatus according to a preferred embodiment of the present invention.

1‧‧‧Electromagnetic wave irradiation device

11‧‧‧Shell

111‧‧‧Upper casing

112‧‧‧ Lower case

113‧‧‧ front cover

114‧‧‧Second junction

12‧‧‧Electromagnetic wave irradiation unit

13‧‧‧Loading unit

131‧‧‧ First Joint Department

132‧‧‧Tray

133‧‧ ‧Baffle

134‧‧‧ heating element

135‧‧‧ glass

14‧‧‧Input module

15‧‧‧Drive unit

16‧‧‧ Temperature Control Unit

17‧‧‧ ‧ body

18‧‧‧Control unit

19‧‧‧Time unit

A‧‧‧cavity

G‧‧‧ Groove

H‧‧‧ openings

M‧‧‧ display module

Claims (9)

An electromagnetic wave irradiation device irradiates an electromagnetic wave to a biochemical substance, the biochemical substance is a substance that can be excited by an electromagnetic wave, and the electromagnetic wave irradiation device comprises: a casing having a cavity; at least one electromagnetic wave irradiation unit is disposed in the casing At least one side of the carrying unit is coupled to the housing and at least partially received in the cavity, the carrying unit is movable relative to the housing, so that the carrying unit has an open state and a closed state, wherein The carrying unit has a first joint portion, and the shell has a second joint portion that cooperates with the first joint portion. The first joint portion and the second joint portion are respectively a slide rail or a slip joint. a slot, or a roller, or a ball or a combination thereof; a driving unit is disposed in the cavity and drives the carrying unit to move relative to the housing; a timing unit is disposed in the housing; a control unit, And the electromagnetic wave irradiation unit is electrically connected; and a filter element is disposed in cooperation with the electromagnetic wave irradiation unit to change the electromagnetic wave emitted by the electromagnetic wave irradiation unit Long. The electromagnetic wave irradiation apparatus according to claim 1, wherein the carrying unit has a tray, and the tray is located in the cavity in the closed state. The electromagnetic wave irradiation device of claim 2, wherein the carrying unit has a heating element, and the heating element is disposed on the support plate. The electromagnetic wave irradiation device according to claim 3, wherein the heating element is an indium tin oxide layer, or a heating resistance wire or an electrothermal tube. The electromagnetic wave irradiation device of claim 3, further comprising: a temperature control unit electrically connected to the heating element. The electromagnetic wave irradiation device of claim 1, wherein the electromagnetic wave has a wavelength range of visible light, and/or ultraviolet light, and/or infrared light, and/or fluorescent light, and/or laser light and/or X. Light. The electromagnetic wave irradiation device according to claim 1, wherein the electromagnetic wave irradiation unit has at least one light emitting diode, a laser diode or a light tube. The electromagnetic wave irradiation device of claim 7, wherein the electromagnetic wave irradiation unit further has at least one frame, the frame system is disposed in the casing, and the diode or the lamp tube is disposed on the frame. The electromagnetic wave irradiation device according to claim 1, wherein the biochemical substance is a photoexcited nucleic acid cleavage reagent.