TWI414265B - Endoscope system - Google Patents

Endoscope system Download PDF

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TWI414265B
TWI414265B TW100122666A TW100122666A TWI414265B TW I414265 B TWI414265 B TW I414265B TW 100122666 A TW100122666 A TW 100122666A TW 100122666 A TW100122666 A TW 100122666A TW I414265 B TWI414265 B TW I414265B
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injection
carbon dioxide
freezing
endoscope system
nozzle
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TW100122666A
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TW201300069A (en
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Chueh Kuan Wang
Min Chen
Chih Yuan Hu
Che Yuan Hong
yi jun Shen
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Univ Nat Cheng Kung
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Abstract

The present invention relates to an endoscope system comprising: an endoscope device, a needle-free injection device and a freezing device. In the endoscope system of the present invention, the endoscope device includes an optical element for acquiring an image; a lighting element disposed on aside of the optical element; and at least one operating holes disposed on aside of the optical element. The needle-free injection device includes an injection supply element for storing an injection; a compression element connected to the injection supply element, wherein the compression element pressurize the injection to form a high-speed jet flow; and an injection delivery pipe inserted into the operating holes, wherein a first nozzle is disposed on one end thereof, the other end of the injection delivery pipe is connected to the injection supply element. Besides, the freezing device includes a freezing source delivery pipe, and a freezing source supply element, wherein one end of the freezing source delivery pipe is assembled with a second nozzle. In addition, the first nozzle and the second nozzle are inserted into the operating holes.

Description

內視鏡系統Endoscope system

本發明係關於一種內視鏡系統,尤指一種適用於內視鏡手術或內視鏡檢查上之內視鏡系統。其係結合無針注射、及冷涷治療之方式,俾能降低病患的痛楚及提高內視鏡手術或內視鏡檢查的品質。The present invention relates to an endoscope system, and more particularly to an endoscope system suitable for endoscopic or endoscopic examination. It is combined with needle-free injection and cold fistula treatment, which can reduce the pain of patients and improve the quality of endoscopic surgery or endoscopy.

一般醫學上進行的檢查或治療過程中,使用內視鏡是一種相當普遍也相當常見的方法。一般而言,醫師在為病患進行內視鏡檢查或治療過程中,係將內視鏡管伸入至人體體腔內部,而用以觀察體內器官等的狀況。而在進行手術治療時,有時亦須以內視鏡作為輔助工具來進行。The use of endoscopes is a fairly common and fairly common method of examination or treatment in general medical practice. In general, during the endoscopic examination or treatment of a patient, the physician extends the endoscope tube into the body cavity to observe the condition of the internal organs and the like. In the case of surgical treatment, it is sometimes necessary to use an endoscope as an auxiliary tool.

當病患接受內視鏡手術治療時,醫師首先藉一內視鏡系統之內視鏡管伸入至人體體腔內部,找到人體內的病原處,病原處例如為一腫瘤。接著,注射一組織液於腫瘤附近的組織上以使組織抬升,組織抬升亦使腫瘤跟隨抬升。最後再對腫瘤進行移除以達到治療的效果。When the patient is treated with endoscopic surgery, the physician first uses an endoscope tube of the endoscope system to extend into the body cavity to find the pathogen in the human body. The pathogen is, for example, a tumor. Next, a tissue fluid is injected onto the tissue near the tumor to raise the tissue, and the tissue elevation also causes the tumor to follow up. Finally, the tumor is removed to achieve the therapeutic effect.

在上述之內視鏡手術治療的過程中,傳統上於腫瘤附近注射組織液係以有針注射的方式,以微針筒注射生理溶液於組織上,而生理溶液例如為生理食鹽水、或纖維素等。In the above-mentioned endoscopic surgical treatment, the tissue fluid is conventionally injected near the tumor in a needle injection manner, and the physiological solution is injected into the tissue by a micro syringe, and the physiological solution is, for example, physiological saline or cellulose. Wait.

然而,病患於接受內視鏡手術治療時,病患先要承受內視鏡管伸入體內所帶來的不適與痛楚,若再以有針注射之方式刺穿組織,將對病患帶來更多不適。再者,有針注射之方式在醫學上係為侵入式之行為,因而可能造成細茵感染的機會增加,不利於病患。However, when patients undergo endoscopic surgery, the patient must first suffer from the discomfort and pain caused by the extension of the endoscopic tube into the body. If the patient is pierced with a needle injection, the patient will be brought to the patient. Come more discomfort. Furthermore, the method of needle injection is medically invasive, and thus may increase the chance of infection with fine bacteria, which is not conducive to patients.

另外,有針注射之方式不易控制組織抬升的時間,若抬升時間過短,極有可能在腫瘤還未完全移除時,生理溶液即失去對腫瘤的抬升能力。此時則必需再進行一次或數次有針注射使腫瘤再次抬升。如此只會更造成病患的不適,更惶論若病患所接受之手術是需要長時間進行的複雜手術,其所承受的不適更是難以想像。In addition, the method of needle injection is not easy to control the time of tissue elevation. If the lifting time is too short, it is highly probable that the physiological solution loses its ability to lift the tumor when the tumor has not been completely removed. At this point, it is necessary to perform one or more injections of the needle to raise the tumor again. This will only cause more discomfort to the patient, let alone the surgery that the patient receives is a complicated operation that takes a long time, and the discomfort it suffers is even more unimaginable.

再者,上述對於腫瘤進行移除的方式,一般而言有熱治療、磁治療、或冷涷治療等方式可供醫師選擇。而其中係以冷涷治療最為廣泛使用。Furthermore, the above methods for removing tumors generally include heat treatment, magnetic treatment, or cold head treatment for the physician to select. Among them, cold sputum treatment is the most widely used.

目前冷涷治療使用的冷涷源係以冰晶為主。即於腫瘤抬升後,發射此冰晶冷涷源至腫瘤,以破壞腫瘤細胞使腫瘤壞死,以移除腫瘤。然而,以冰晶為主之冷涷源在冷涷的速度上並不夠快,而且,此冷涷源若發射的方向控制不當或冷涷源溢散開,則容易破壞腫瘤附近正常的細胞,造成週圍正常的細胞壞死。At present, the cold sputum source used in cold head treatment is mainly ice crystal. That is, after the tumor is elevated, the ice crystal cold sputum is emitted to the tumor to destroy the tumor cells to cause tumor necrosis to remove the tumor. However, the cold sputum source based on ice crystals is not fast enough at the speed of cold sputum. Moreover, if the direction of emission of the cold sputum source is improperly controlled or the cold sputum source overflows, it is easy to destroy the normal cells near the tumor, causing the surrounding Normal cell necrosis.

由上述說明可知,若欲降低病患的痛楚及提高內視鏡手術或內視鏡檢查的品質,現有的內視鏡手術技術,在組織抬升與腫瘤移除的技術上仍有需要改進的空間。It can be seen from the above description that if the pain of the patient is to be reduced and the quality of endoscopic surgery or endoscopy is improved, the existing endoscopic surgery technology still needs room for improvement in the technique of tissue elevation and tumor removal. .

本發明之主要目的係在提供一種內視鏡系統,可用於內視鏡手術或內視鏡檢查上。其係結合無針注射、及冷涷治療之方式,俾能降低病患的痛楚及提高內視鏡手術或內視鏡檢查的品質。The primary object of the present invention is to provide an endoscope system that can be used for endoscopic or endoscopic examination. It is combined with needle-free injection and cold fistula treatment, which can reduce the pain of patients and improve the quality of endoscopic surgery or endoscopy.

本發明之另一目的係在提供一種內視鏡系統,可用於內視鏡手術或內視鏡檢查上。其係結合無針注射、及以二氧化碳雪花為冷涷源之冷涷治療之方式,俾能降低病患的痛楚及提高內視鏡手術或內視鏡檢查的品質。Another object of the present invention is to provide an endoscope system that can be used for endoscopic or endoscopic examination. It combines needle-free injection and cold head treatment with carbon dioxide snow as a source of cold, which can reduce the pain of patients and improve the quality of endoscopic surgery or endoscopy.

為達成上述目的,本發明之內視鏡系統,包括:一內視鏡裝置、一無針式注射裝置、及一冷凍裝置。其中,內視鏡裝置包含:一光學元件,係用以擷取一影像;一照明元件,係配置於此光學元件之一側;及至少一操作孔,係配置於此照明元件之一側。無針式注射裝置包含:一注射液供應元件,係儲存有一注射液於其內;一加壓元件,係連接至此注射液供應元件,並對此注射液加壓形成一高速注射液噴流;及一注射液輸送管,此注射液輸送管之一端設有一第一噴嘴,此第一噴嘴係穿入至此操作孔,此注射液輸送管之另一端係連接至此注射液供應元件。再者,冷凍裝置包含:一冷凍源供應元件,係儲存有一冷凍源於其中;及一冷凍源輸送管,係與此冷凍源供應元件連接,此冷凍源輸送管之一端設有一第二噴嘴,此第二噴嘴係穿入至此操作孔。To achieve the above object, an endoscope system of the present invention includes: an endoscope device, a needleless injection device, and a freezing device. The endoscope device includes: an optical component for capturing an image; an illumination component disposed on one side of the optical component; and at least one operation hole disposed on one side of the illumination component. The needle-free injection device comprises: an injection supply component for storing an injection solution therein; a pressurizing component connected to the injection supply component, and pressurizing the injection to form a high-speed injection jet; An injection tube, one end of the injection tube is provided with a first nozzle, the first nozzle is inserted into the operation hole, and the other end of the injection tube is connected to the injection supply element. Furthermore, the freezing device comprises: a freezing source supply component, wherein a freezing source is stored therein; and a freezing source conveying pipe is connected to the freezing source supply component, and a second nozzle is disposed at one end of the freezing source conveying pipe This second nozzle penetrates into this operation hole.

其中,內視鏡裝置係尋找出一病原處之位置,無針式注射裝置經由此第一噴嘴噴射一注射液至病原處鄰近之組織層上,以使組織層抬升,冷凍裝置經由第二噴嘴噴射此冷凍源至此病原處。Wherein, the endoscope device finds a position of a pathogen through which the needle-free injection device ejects an injection solution to a tissue layer adjacent to the pathogen to lift the tissue layer, and the freezing device passes through the second nozzle Spray this frozen source to the pathogen.

於本發明之內視鏡系統中,首先以內視鏡裝置進入一病患體內,並藉由此光學元件的輔助,擷取病患體內的影像以尋找出病原處之位置。病原處可為一長有瘜肉之組織,或一長有腫瘤之組織。人體體內並無光源,然而此照明元件係可提供充足之光源以輔助以內視鏡裝置於人體體內尋找病原處。In the endoscope system of the present invention, an endoscope device is first introduced into a patient, and with the aid of the optical component, an image of the patient is captured to find the location of the pathogen. The pathogen can be a tissue with a long fat, or a tissue with a long tumor. There is no light source in the human body, but this lighting element provides a sufficient light source to assist in finding the pathogen in the human body with the endoscope device.

而當尋找出病原處後,此內視鏡系統之無針式注射裝置經由此第一噴嘴噴射一注射液至病原處鄰近之組織層上。經由適當的計算與控制,注射液係穿透組織層之表面,並在一定的深度停留於組織層內,如此注射液便可推升組織層,使組織層抬升,而位於組織層上之病原處亦跟隨著抬升。When the pathogen is found, the needleless injection device of the endoscope system injects an injection solution through the first nozzle to the tissue layer adjacent to the pathogen. Through proper calculation and control, the injection penetrates the surface of the tissue layer and stays in the tissue layer at a certain depth, so that the injection can push up the tissue layer and lift the tissue layer, while the pathogen on the tissue layer The place is also followed by ascending.

其中,注射液之選用並無限制,其較佳為一具生物可相容性之溶液,具生物可相容性之溶液例如可為甲基纖維素(Methylcellulose)、羥丙基甲基纖維素(hydroxypropyl methylcellulose)、褐藻膠、生理食鹽水、或甘油。不同之注射液具有不同的溶液特性,可維持組織抬升的時間長短亦不相同,可視不同之使用需求選用不同的注射液。The selection of the injection solution is not limited, and it is preferably a biocompatible solution, and the biocompatible solution may be, for example, Methylcellulose or hydroxypropylmethylcellulose. (hydroxypropyl methylcellulose), alginate, physiological saline, or glycerin. Different injections have different solution characteristics, and the length of time for maintaining tissue uplift is also different. Different injection solutions can be selected according to different use requirements.

再者,將注射液加壓形成高速注射液噴流之加壓裝置的加壓方式並無限制,其加壓裝置之加壓方式係可為電加壓方式、或活塞加壓方式。加壓方式的選用可視不同需求而定。例如,欲注射之處之組織層有厚薄的不同、不同手術欲注射的深度不同等因素。Further, the pressurization method of pressurizing the injection liquid to form a jet of the high-speed injection liquid is not limited, and the pressurization method of the pressurizing device may be an electric pressurization method or a piston pressurization method. The choice of pressurization method can be determined according to different needs. For example, the tissue layer where the injection is to be made has different thicknesses and different depths of different surgical injections.

此外,由第一噴嘴噴射之注射液之噴射壓力係介於70bar至150bar之間,而注射液噴射至組織層上之角度係介於20度至90之間,再者,組織層抬升之抬升高度係介於1mm至15mm之間,以及,組織層抬升之抬升時間係介於1分鐘至60分鐘之間。In addition, the injection pressure of the injection liquid injected by the first nozzle is between 70 and 150 bar, and the angle of the injection liquid sprayed onto the tissue layer is between 20 and 90, and further, the rise of the tissue layer is raised. The height is between 1 mm and 15 mm, and the lifting time of the tissue layer is between 1 minute and 60 minutes.

當病原處抬升後,再搭配本發明之內視鏡系統之冷凍裝置,此冷凍裝置之冷凍源供應元件儲存有冷凍源於其中,冷凍源係藉由冷凍源輸送管做傳輸,冷凍源輸送管之一端設有一第二噴嘴,冷凍源並再經由此第二噴嘴發射至此病原處,以破壞病原處使病原處之病變細胞壞死,達到治療之效果。When the pathogen is raised, the refrigeration device of the endoscope system of the present invention is further equipped with a freezing source supply component in which the freezing source is stored, and the freezing source is transported by the freezing source conveying pipe, and the freezing source conveying pipe is used. One end is provided with a second nozzle, and the freezing source is further emitted to the pathogen via the second nozzle to destroy the pathogen and cause the diseased cells at the pathogen to be necrotic, thereby achieving the therapeutic effect.

其中,此冷凍源較佳為液態氮,但並不限定為液態氮。其他可達到冷凍治療之效果的冷凍源亦可適用於本發明之內視鏡系統中。Among them, the freezing source is preferably liquid nitrogen, but is not limited to liquid nitrogen. Other sources of freezing that achieve the effects of cryotherapy may also be suitable for use in the endoscope system of the present invention.

再者,本發明之內視鏡裝置更包含二操作孔,第一噴嘴及第二噴嘴可分別穿入至此二操作孔中。此外,操作孔之數目並無限制,亦可僅為單一操作孔,如此,第一噴嘴及第二噴嘴即皆穿入至此單一操作孔中。Furthermore, the endoscope device of the present invention further includes two operation holes through which the first nozzle and the second nozzle can be respectively inserted. In addition, the number of the operation holes is not limited, and may be only a single operation hole, so that the first nozzle and the second nozzle penetrate into the single operation hole.

為達成上述目的,本發明之內視鏡系統,包括:一內視鏡裝置、一無針式注射裝置、及一冷凍裝置。其中,內視鏡裝置包含:一光學元件,係用以擷取一影像;一照明元件,係配置於此光學元件之一側;及至少一操作孔,係配置於此照明元件之一側。無針式注射裝置包含:一注射液供應元件,係儲存有一注射液於其內;一加壓元件,係連接至此注射液供應元件,並對此注射液加壓形成一高速注射液噴流;及一注射液輸送管,此注射液輸送管之一端設有一第一噴嘴,此第一噴嘴係穿入至此操作孔,此注射液輸送管之另一端係連接至此注射液供應元件。再者,冷凍裝置包含:一冷凍源供應元件,係儲存有一冷凍源於其中;及一冷凍源輸送管,係與此冷凍源供應元件連接,此冷凍源輸送管之一端設有一第二噴嘴,此第二噴嘴係穿入至此操作孔。其中,此冷凍裝置係為一二氧化碳雪花冷凍裝置,此冷凍源輸送管係為一二氧化碳雪花輸送管,此冷凍源供應元件係為一二氧化碳供應元件,此二氧化碳雪花冷凍裝置更包括一二氧化碳雪花形成元件,係與此二氧化碳雪花輸送管連接。To achieve the above object, an endoscope system of the present invention includes: an endoscope device, a needleless injection device, and a freezing device. The endoscope device includes: an optical component for capturing an image; an illumination component disposed on one side of the optical component; and at least one operation hole disposed on one side of the illumination component. The needle-free injection device comprises: an injection supply component for storing an injection solution therein; a pressurizing component connected to the injection supply component, and pressurizing the injection to form a high-speed injection jet; An injection tube, one end of the injection tube is provided with a first nozzle, the first nozzle is inserted into the operation hole, and the other end of the injection tube is connected to the injection supply element. Furthermore, the freezing device comprises: a freezing source supply component, wherein a freezing source is stored therein; and a freezing source conveying pipe is connected to the freezing source supply component, and a second nozzle is disposed at one end of the freezing source conveying pipe This second nozzle penetrates into this operation hole. Wherein, the freezing device is a carbon dioxide snowflake freezing device, the freezing source conveying pipe is a carbon dioxide snowflake conveying pipe, the freezing source supply component is a carbon dioxide supply component, and the carbon dioxide snowflake freezing device further comprises a carbon dioxide snowflake forming component. , is connected to this carbon dioxide snowflake conveying pipe.

其中,上述之二氧化碳供應元件內所儲存之冷凍源係為二氧化碳雪花冷凍源,二氧化碳雪花輸送管之另一端係連接至二氧化碳雪花形成元件,內視鏡裝置係尋找出一病原處之位置,無針式注射裝置經由第一噴嘴噴射一注射液至病原處鄰近之組織層上,以使此組織層抬升,該二氧化碳雪花冷凍裝置經由第二噴嘴發射此冷凍源至病原處。Wherein, the freezing source stored in the carbon dioxide supply component is a carbon dioxide snowflake freezing source, and the other end of the carbon dioxide snowflake conveying pipe is connected to the carbon dioxide snowflake forming element, and the endoscope device is to find a position of a pathogen, no needle The injection device ejects an injection solution through the first nozzle to a tissue layer adjacent to the pathogen to lift the tissue layer, and the carbon dioxide snowflake freezing device emits the freezing source to the pathogen via the second nozzle.

於本發明之內視鏡系統中,首先以內視鏡裝置進入一病患體內,並藉由此光學元件的輔助,擷取病患體內的影像以尋找出病原處之位置。病原處可為一長有瘜肉之組織,或一長有腫瘤之組織。人體體內並無光源,然而此照明元件係可提供充足之光源以輔助以內視鏡裝置於人體體內尋找病原處。In the endoscope system of the present invention, an endoscope device is first introduced into a patient, and with the aid of the optical component, an image of the patient is captured to find the location of the pathogen. The pathogen can be a tissue with a long fat, or a tissue with a long tumor. There is no light source in the human body, but this lighting element provides a sufficient light source to assist in finding the pathogen in the human body with the endoscope device.

而當尋找出病原處後,此內視鏡系統之無針式注射裝置經由此第一噴嘴噴射一注射液至病原處鄰近之組織層上。經由適當的計算與控制,注射液係穿透組織層之表面,並在一定的深度停留於組織層內,如此注射液便可推升組織層,使組織層抬升,而位於組織層上之病原處亦跟隨著抬升。When the pathogen is found, the needleless injection device of the endoscope system injects an injection solution through the first nozzle to the tissue layer adjacent to the pathogen. Through proper calculation and control, the injection penetrates the surface of the tissue layer and stays in the tissue layer at a certain depth, so that the injection can push up the tissue layer and lift the tissue layer, while the pathogen on the tissue layer The place is also followed by ascending.

其中,注射液之選用並無限制,其較佳為一具生物可相容性之溶液,具生物可相容性之溶液例如可為甲基纖維素(Methylcellulose)、羥丙基甲基纖維素(hydroxypropyl methylcellulose)、褐藻膠、生理食鹽水、或甘油。不同之注射液具有不同的溶液特性,可維持組織抬升的時間長短亦不相同,可視不同之使用需求選用不同的注射液。The selection of the injection solution is not limited, and it is preferably a biocompatible solution, and the biocompatible solution may be, for example, Methylcellulose or hydroxypropylmethylcellulose. (hydroxypropyl methylcellulose), alginate, physiological saline, or glycerin. Different injections have different solution characteristics, and the length of time for maintaining tissue uplift is also different. Different injection solutions can be selected according to different use requirements.

再者,將注射液加壓形成高速注射液噴流之加壓裝置的加壓方式並無限制,其加壓裝置之加壓方式係可為電加壓方式、或活塞加壓方式。加壓方式的選用可視不同需求而定。例如,欲注射之處之組織層有厚薄的不同、不同手術欲注射的深度不同等因素。Further, the pressurization method of pressurizing the injection liquid to form a jet of the high-speed injection liquid is not limited, and the pressurization method of the pressurizing device may be an electric pressurization method or a piston pressurization method. The choice of pressurization method can be determined according to different needs. For example, the tissue layer where the injection is to be made has different thicknesses and different depths of different surgical injections.

其中,本發明之內視鏡系統之注射液噴射方式係可為兩段式噴射。於第一噴射階段內,加壓元件對注射液施加一較高之壓力使注射液具備較高之能量以便突破組織層。而於第二噴射階段內,加壓元件係對注射液施加一較低之壓力,以防止注射液因攜帶過高能量而更向下突破組織層,對組織層造成不必要之破壞。再者,兩噴射階段內所使用之注射液係可視需求而任意選用。The injection method of the endoscope system of the present invention may be a two-stage injection. During the first injection phase, the pressurizing element applies a higher pressure to the injection to give the injection a higher energy to break through the tissue layer. In the second injection phase, the pressurizing element applies a lower pressure to the injection to prevent the injection from breaking through the tissue layer due to the excessive energy being carried, causing unnecessary damage to the tissue layer. Furthermore, the injection solution used in the two injection stages can be arbitrarily selected as needed.

此外,第一噴嘴噴射之該注射液之噴射壓力係介於70bar至150bar之間,而注射液噴射至組織層上之角度係介於20度至90之間,再者,組織層抬升之抬升高度係介於1mm至15mm之間,以及,組織層抬升之抬升時間係介於1分鐘至60分鐘之間。In addition, the injection pressure of the injection liquid sprayed by the first nozzle is between 70 and 150 bar, and the angle of the injection liquid sprayed onto the tissue layer is between 20 and 90, and further, the rise of the tissue layer is raised. The height is between 1 mm and 15 mm, and the lifting time of the tissue layer is between 1 minute and 60 minutes.

當病原處抬升後,再搭配此二氧化碳雪花冷凍裝置,此二氧化碳雪花冷凍裝置係發射一二氧化碳雪花冷凍源至病原處,以破壞病原處使病原處之病變細胞壞死,達到治療之效果。When the pathogen is raised, the carbon dioxide snowflake freezing device is combined with a carbon dioxide snowflake freezing device to emit a carbon dioxide snowflake freezing source to the pathogen to destroy the pathogen at the pathogen to cause necrosis of the diseased cells at the pathogen, thereby achieving the therapeutic effect.

此外,本發明之內視鏡裝置更包含二操作孔,第一噴嘴及第二噴嘴可分別穿入至此二操作孔中。此外,操作孔之數目並無限制,亦可僅為單一操作孔,如此,第一噴嘴及第二噴嘴即皆穿入至此單一操作孔中。In addition, the endoscope device of the present invention further includes two operation holes through which the first nozzle and the second nozzle can be respectively inserted. In addition, the number of the operation holes is not limited, and may be only a single operation hole, so that the first nozzle and the second nozzle penetrate into the single operation hole.

再者,二氧化碳雪花形成元件之形狀係為直管形,或可為圓球形。此外,二氧化碳係為高壓液態二氧化碳,而二氧化碳雪花冷凍源之型態係對應於此第二噴嘴之形態,亦即可藉由改變第二噴嘴之形態來發射不同型狀的二氧化碳雪花冷凍源。Further, the shape of the carbon dioxide snowflake forming member is a straight tube shape or may be a spherical shape. In addition, the carbon dioxide is a high-pressure liquid carbon dioxide, and the carbon dioxide snowflake freezing source corresponds to the shape of the second nozzle, and the carbon dioxide snowflake freezing source of different shapes can be emitted by changing the shape of the second nozzle.

其中,因本發明之內視鏡系統所使用之冷凍源為二氧化碳雪花,該冷凍源之型態係為固態,冷凍源自第二噴嘴發射後可更準確的到達病源處而不致溢散,且其冷凍速度快。再者,二氧化碳之取得相當容易,且成本相較於其他成份之冷凍源更低,更具經濟價值。再者,二氧化碳雪花亦具有止血的功能,相當適合用於手術上。Wherein, the freezing source used in the endoscope system of the present invention is carbon dioxide snowflake, the type of the freezing source is solid, and the freezing from the second nozzle can more accurately reach the pathogen without being overflowed, and It has a fast freezing speed. Moreover, carbon dioxide is relatively easy to obtain, and the cost is lower and more economical than other components. In addition, carbon dioxide snowflake also has the function of stopping bleeding, which is quite suitable for surgery.

再者,本發明之內視鏡系統可改變第二噴嘴之形態來發射不同型狀的二氧化碳雪花冷凍源,如此即可控制二氧化碳雪花的顆粒大小。若病源處之面積較大,則可控制本發明之內視鏡系統發射較大顆粒之二氧化碳雪花冷凍源,而若病源處之面積較小,則可控制本發明之內視鏡系統發射較小顆粒之二氧化碳雪花冷凍源,如此可減少冷凍源對病源處周圍正常組織或細胞的破壞。Furthermore, the endoscope system of the present invention can change the shape of the second nozzle to emit different types of carbon dioxide snowflake freezing sources, thus controlling the particle size of the carbon dioxide snowflake. If the area of the disease source is large, the endoscope system of the present invention can control the carbon dioxide snowflake freezing source of larger particles, and if the area of the disease source is small, the emission of the endoscope system of the present invention can be controlled to be small. The carbon dioxide snowflake freezing source of the particles can reduce the damage of the freezing source to normal tissues or cells around the source.

本發明之內視鏡系統可適用於任何需要內視鏡系統做為輔助之手術,例如腸道手術、心肺繞道手術,或者可應用在無針式黏膜抬升注射技術中。The endoscope system of the present invention can be applied to any surgery that requires an endoscopic system as an aid, such as bowel surgery, cardiopulmonary bypass surgery, or can be applied to needleless mucosal lift injection techniques.

以下係藉由特定的具體實施例說明本發明之實施方式,熟習此技藝之人士可由本說明書所揭示之內容輕易地了解本發明之其他優點與功效。此外,本發明亦可藉由其他不同的具體實施例加以施行或應用,且本說明書中的各項細節亦可基於不同觀點與應用,而在不悖離本發明之精神下進行各種修飾與變更。The embodiments of the present invention are described by way of specific examples, and those skilled in the art can readily appreciate the other advantages and advantages of the present invention. In addition, the present invention may be embodied or applied in various other specific embodiments, and the details of the present invention may be variously modified and changed without departing from the spirit and scope of the invention. .

實施例1Example 1

本實施例之內視鏡系統可用於內視鏡手術或內視鏡檢查上。其係結合無針注射、及冷涷治療之方式,俾能降低病患的痛楚及提高內視鏡手術或內視鏡檢查的品質。The endoscope system of this embodiment can be used for endoscopic surgery or endoscopy. It is combined with needle-free injection and cold fistula treatment, which can reduce the pain of patients and improve the quality of endoscopic surgery or endoscopy.

有關本實施例之內視鏡系統,請同時參照圖1及圖2。圖1係本發明第一實施例之內視鏡系統之示意圖。如圖1所示,本發明第一實施例之內視鏡系統包括:一內視鏡裝置11、一無針式注射裝置12、及一冷凍裝置13。而圖2係圖1中A部分之內視鏡裝置之放大圖。如圖2所示,內視鏡裝置11包含一光學元件111、一照明元件112、及至少一操作孔113。光學元件111係用以擷取一影像,照明元件112係用以提供光源,並配置於光學元件111之一側,而操作孔113係配置於照明元件112之一側。Regarding the endoscope system of the present embodiment, please refer to FIG. 1 and FIG. 2 at the same time. 1 is a schematic view of an endoscope system according to a first embodiment of the present invention. As shown in FIG. 1, an endoscope system according to a first embodiment of the present invention includes an endoscope device 11, a needleless injection device 12, and a freezing device 13. 2 is an enlarged view of the endoscope device of Part A of FIG. 1. As shown in FIG. 2, the endoscope device 11 includes an optical element 111, an illumination element 112, and at least one operation aperture 113. The optical element 111 is used to capture an image, the illumination element 112 is used to provide a light source, and is disposed on one side of the optical element 111, and the operation hole 113 is disposed on one side of the illumination element 112.

再者,無針式注射裝置12包含一注射液供應元件121、一加壓元件122、及一注射液輸送管123。注射液供應元件121係儲存有一注射液於其內,加壓元件122係連接至注射液供應元件121,用以對注射液加壓,使注射液形成一高速注射液噴流。再者,注射液輸送管123之一端設有一第一噴嘴1231,此第一噴嘴1231係穿入至操作孔113中,注射液輸送管123之另一端係連接至注射液供應元件121。Further, the needleless injection device 12 includes an injection supply member 121, a pressurizing member 122, and an injectable solution delivery tube 123. The injection supply member 121 stores therein an injection solution, and the pressurizing member 122 is coupled to the injection supply member 121 for pressurizing the injection to form a high-speed injection jet. Further, one end of the injection delivery tube 123 is provided with a first nozzle 1231, the first nozzle 1231 is inserted into the operation hole 113, and the other end of the injection solution delivery tube 123 is connected to the injection solution supply member 121.

再者,冷凍裝置13包含一冷凍源輸送管131、及一冷凍源供應元件132。冷凍源輸送管131係與冷凍源供應元件132連接,冷凍源輸送管131之一端設有一第二噴嘴1311,第二噴嘴係1311穿入至操作孔113中。而冷凍源供應元件132內係儲存有一冷凍源。Furthermore, the freezing device 13 includes a freezing source delivery pipe 131 and a freezing source supply element 132. The freezing source conveying pipe 131 is connected to the freezing source supply member 132, and one end of the freezing source conveying pipe 131 is provided with a second nozzle 1311, and the second nozzle system 1311 is inserted into the operation hole 113. A source of refrigeration is stored in the source of refrigeration source 132.

以下將詳述有關本實施例之實施方式。首先,如圖1所示,先將內視鏡裝置11伸入一病患之體內。內視鏡裝置11藉由其照明元件112所提供之光源以及光學元件111所擷取之影像,找到病患體內之一病原處14之正確位置,並接著對該病原處14進行後續之治療或移除。人體體內並無光源,然而此照明元件112係可提供充足之光源以輔助以內視鏡裝置11於病患之體內尋找病原處14。Embodiments relating to the present embodiment will be described in detail below. First, as shown in Fig. 1, the endoscope device 11 is first inserted into a patient's body. The endoscope device 11 finds the correct position of one of the pathogens 14 in the patient by the light source provided by the illumination element 112 and the image captured by the optical element 111, and then performs subsequent treatment on the pathogen 14 or Remove. There is no light source in the body, however, the illumination element 112 provides a sufficient source of light to assist in finding the pathogen 14 in the patient's body with the endoscopic device 11.

其中,病原處14可為瘜肉或腫瘤,而病原處14係生長於病患體內之一組織層15上。接著,於找到病原處14後,無針式注射裝置12之加壓元件122對儲存於注射液供應元件121之注射液加壓,使注射液形成一高速注射液噴流,此高速注射液噴流經注射液輸送管123之傳送,並經由第一噴嘴1231噴射至病原處14鄰近之組織層15上,利用高速注射液噴流在高速時攜帶的能量突破組織層15表面。注射液在突破組織層15表面停留於組織層15內,以使該組織層15抬升。Among them, the pathogen 14 may be a fat or a tumor, and the pathogen 14 is grown on one of the tissue layers 15 of the patient. Next, after the pathogen 14 is found, the pressing member 122 of the needle-free injection device 12 pressurizes the injection solution stored in the injection supply member 121 to form a high-speed injection jet, which is sprayed through the high-speed injection solution. The delivery of the infusion delivery tube 123 is sprayed through the first nozzle 1231 to the tissue layer 15 adjacent to the pathogen 14, and the energy carried by the high velocity injection jet at high speed breaks through the surface of the tissue layer 15. The injection solution stays in the tissue layer 15 on the surface of the breakthrough tissue layer 15 to cause the tissue layer 15 to rise.

無針式注射裝置12之注射液供應元件121係儲存有注射液於其內,注射液係為具生物可相容性之溶液。例如可為:甲基纖維素(Methylcellulose)、羥丙基甲基纖維素(hydroxypropyl methylcellulose)、褐藻膠、生理食鹽水、或甘油等。The injection supply unit 121 of the needle-free injection device 12 stores therein an injection solution which is a biocompatible solution. For example, it may be: methyl cellulose, hydroxypropyl methylcellulose, alginate, physiological saline, or glycerin.

再者,本實施例之注射液噴射方式係為兩段式噴射。如圖3所示,圖3係本發明之注射液噴射方式之時間/壓力關係示意圖。如圖3所示,橫軸係代表時間(t),而縱軸係代表壓力(p)。在第一噴射階段ti 內,因注射液需突破組織層之表面,故在第一噴射階段ti 內,加壓元件122係對注射液施加一較高之壓力(pi )使注射液具備較高之能量以便突破組織層。於本實施例中,pi 係為150bar。Furthermore, the injection liquid injection method of the present embodiment is a two-stage injection. As shown in Fig. 3, Fig. 3 is a schematic diagram showing the time/pressure relationship of the injection method of the present invention. As shown in Fig. 3, the horizontal axis represents time (t) and the vertical axis represents pressure (p). In the first injection phase t i , since the injection solution needs to break through the surface of the tissue layer, in the first injection phase t i , the pressing member 122 applies a higher pressure (p i ) to the injection to make the injection. Have higher energy to break through the organizational layer. In the present embodiment, the p i is 150 bar.

接著,在注射液突破組織層後,即進入第二噴射階段td 。在第二噴射階段td 內,加壓元件122係對注射液施加一較低之壓力(pd ),以防止注射液因攜帶過高能量而更向下突破組織層,對組織層造成不必要之破壞。如此一來,具備較低能量之注射液便會停留於組織層內,進而使得組織層抬升。於本實施例中,pd 係為70bar。Subsequently, after the injection break the tissue layers, i.e. into the second spraying period t d. The t d, the pressing member 122 is applied to a system of lower pressure (p d) of the second injection in the injection stage, in order to prevent excessive injection due to carry more energy to break down the tissue layers, the tissue layers without causing Necessary destruction. As a result, the injection with lower energy will stay in the tissue layer, which will cause the tissue layer to rise. In the present embodiment, the p d is 70 bar.

再者,於本實施例中,第一噴射階段所使用之注射液係選用生理食鹽水,以達到快速突破組織層之效果,且生理食鹽水對生物細胞而較不具刺激性。而第二噴射階段所使用之注射液係選用甘油,因甘油較具黏性,可拉長注射液停留於組織層之時間。Furthermore, in the present embodiment, the injection solution used in the first injection stage is selected from physiological saline to achieve a rapid breakthrough of the tissue layer, and the physiological saline is less irritating to biological cells. The injection solution used in the second injection stage is glycerin. Because glycerin is more viscous, it can lengthen the time that the injection stays in the tissue layer.

其中,於本實施例中,注射液噴射至組織層上之角度係介於20度至90之間。並再搭配上述之兩階段式之噴射方式,可使組織層抬升之抬升高度介於1mm至15mm之間,而組織層抬升之抬升時間可達到60分鐘。Wherein, in the embodiment, the angle at which the injection liquid is sprayed onto the tissue layer is between 20 degrees and 90 degrees. And with the above two-stage spray method, the lifting height of the tissue layer can be raised between 1mm and 15mm, and the lifting time of the tissue layer lifting can reach 60 minutes.

由上述內容可知,本發明之內視鏡系統之無針式注射裝置可藉由調整上述各種不同的參數(例如注射液的選擇,注射角度或注射壓力等),達成不同效果之組織層抬升。因此,本發明之內視鏡系統俾可滿足不同之需求內視鏡手術或內視鏡檢查。From the above, it can be seen that the needleless injection device of the endoscope system of the present invention can achieve different effects of tissue layer uplift by adjusting various parameters described above (e.g., selection of injection solution, injection angle or injection pressure, etc.). Therefore, the endoscope system of the present invention can meet different needs for endoscopic surgery or endoscopy.

再者,組織層抬升後進而帶動其上之病原處跟著抬升。接著,冷凍裝置13之冷凍源供應元件132所儲存之冷凍源經由冷凍源輸送管131之傳輸,並再由第二噴嘴1311發射至此病原處14,以破壞病原處14使病原處14之病變細胞壞死,達到治療之效果。In addition, the tissue layer is lifted up and then the pathogens on it are followed up. Then, the frozen source stored in the freezing source supply unit 132 of the freezing device 13 is transported via the freezing source delivery tube 131, and then emitted by the second nozzle 1311 to the pathogen 14 to destroy the pathogenic region 14 to cause the diseased cells at the pathogen 14. Necrosis, the effect of treatment.

其中,冷凍裝置內係儲存有冷凍源,於本實施中,冷凍源係為液態氮。液態氮經由冷凍源輸送管傳送至第二噴嘴,並再經由第二噴嘴發射至病原處。Among them, a freezing source is stored in the freezing device, and in the present embodiment, the freezing source is liquid nitrogen. The liquid nitrogen is delivered to the second nozzle via the freezing source delivery tube and is then emitted to the pathogen via the second nozzle.

實施例2Example 2

本實施例之內視鏡系統可用於內視鏡手術或內視鏡檢查上。其係結合無針注射、及以二氧化碳雪花為冷涷源之冷涷治療之方式,俾能降低病患的痛楚及提高內視鏡手術或內視鏡檢查的品質。The endoscope system of this embodiment can be used for endoscopic surgery or endoscopy. It combines needle-free injection and cold head treatment with carbon dioxide snow as a source of cold, which can reduce the pain of patients and improve the quality of endoscopic surgery or endoscopy.

有關本實施例之內視鏡系統,請同時參照圖1及圖4。其實施方式係與實施例1所述之內容相似,而其差異處係在於:本實施例2之冷凍裝置係為一二氧化碳雪花冷凍裝置。本實施例之實施方式與實施例1之實施方式因差異僅在於冷凍裝置之實施方式不同,故於本實施例中僅說明二氧化碳雪花冷凍裝置的實施方式,其相同之部分便不再贅述。Regarding the endoscope system of the present embodiment, please refer to FIG. 1 and FIG. 4 at the same time. The embodiment is similar to the content described in Embodiment 1, and the difference is that the freezing device of the second embodiment is a carbon dioxide snowflake freezing device. The embodiment of the present embodiment differs from the embodiment of the first embodiment only in the embodiment of the refrigeration device. Therefore, in the present embodiment, only the embodiment of the carbon dioxide snowflake freezing device will be described, and the same portions will not be described again.

其中,圖4係本發明第二實施例之內視鏡系統之示意圖。其中,實施例2之係將實施例1所述之冷凍裝置以二氧化碳雪花冷凍裝置取代。如圖4所示,本實施例之二氧化碳雪花冷凍裝置41所使用之冷凍源係為一二氧化碳雪花冷凍源(二氧化碳雪花冷凍裝置41即對應實施例1中所述之冷凍裝置)。再者,二氧化碳雪花冷凍裝置41包含一二氧化碳雪花輸送管411(二氧化碳雪花輸送管411即對應實施例1中所述之冷凍源輸送管)、一二氧化碳供應元件412(二氧化碳供應元件412實施例1中所述之冷凍源供應元件)、及一二氧化碳雪花形成元件413。4 is a schematic view of an endoscope system according to a second embodiment of the present invention. In the second embodiment, the freezing apparatus described in the first embodiment is replaced by a carbon dioxide snow freezing apparatus. As shown in FIG. 4, the freezing source used in the carbon dioxide snow freezing apparatus 41 of the present embodiment is a carbon dioxide snowflake freezing source (the carbon dioxide snow freezing apparatus 41, that is, the freezing apparatus described in the first embodiment). Furthermore, the carbon dioxide snowflake freezing device 41 comprises a carbon dioxide snowflake conveying pipe 411 (carbon dioxide snowflake conveying pipe 411 corresponding to the freezing source conveying pipe described in the first embodiment), and a carbon dioxide supply element 412 (carbon dioxide supply element 412 in the first embodiment) The freezing source supply element) and a carbon dioxide snowflake forming element 413.

其中,二氧化碳供應元件412內係儲存有二氧化碳,做為本實施例之二氧化碳雪花冷凍裝置41之冷凍源。二氧化碳雪花輸送管411係連接二氧化碳供應元件412與二氧化碳雪花形成元件413,二氧化碳供應元件所提供之二氧化碳經由二氧化碳雪花輸送管411傳送至二氧化碳雪花形成元件413。二氧化碳雪花形成元件413之另一端則可與實施例1中之第二噴嘴連接。Among them, carbon dioxide is stored in the carbon dioxide supply element 412 as a freezing source of the carbon dioxide snowflake freezing apparatus 41 of the present embodiment. The carbon dioxide snowflake conveying pipe 411 is connected to the carbon dioxide supply element 412 and the carbon dioxide snowflake forming element 413, and the carbon dioxide supplied from the carbon dioxide supply element is sent to the carbon dioxide snowflake forming element 413 via the carbon dioxide snowflake conveying pipe 411. The other end of the carbon dioxide snowflake forming member 413 can be connected to the second nozzle of Embodiment 1.

請再參閱圖5,圖5係二氧化碳雪花形成元件之內部構造示意圖,其更詳細說明上述之二氧化碳雪花形成元件413之內部構造。如圖5所示,二氧化碳雪花形成元件413更包含:一外管4131、一內管4132、一栓塞環4133、一雪花形成腔體4134、以及一噴口4135。其中,外管4131係用以保護內管4132,並可作為支撐結構。再者,外管4131及內管4132具可撓性,因此,二氧化碳雪花形成元件413即可設置於亦具可撓性之內視鏡管中。Referring to FIG. 5 again, FIG. 5 is a schematic diagram showing the internal structure of the carbon dioxide snowflake forming element, which explains the internal structure of the above-described carbon dioxide snowflake forming element 413 in more detail. As shown in FIG. 5, the carbon dioxide snowflake forming member 413 further includes an outer tube 4131, an inner tube 4132, a plug ring 4133, a snowflake forming cavity 4134, and a spout 4135. The outer tube 4131 is used to protect the inner tube 4132 and can serve as a support structure. Furthermore, since the outer tube 4131 and the inner tube 4132 are flexible, the carbon dioxide snowflake forming element 413 can be placed in an flexible endoscope tube.

再者,本實施例中做為冷凍源之二氧化碳(CO2 )則經由內管4132輸送至噴口4135,噴口4135係可控制二氧化碳進入雪花形成腔體4134之流量。而二氧化碳則於雪花形成腔體4134內形成二氧化碳雪花冷凍源。栓塞環4133則可防止形成於雪花形成腔體4134內之二氧化碳雪花冷凍源回流至外管4131及內4132之間的空隙。二氧化碳雪花冷凍源則再經由二氧化碳雪花輸送管411傳送至第二噴嘴,並由第二噴嘴發射而出。再者,二氧化碳係為高壓液態二氧化碳,當二氧化碳被傳送至二氧化碳雪花形成元件413時,其壓力下降並於二氧化碳雪花形成元件413中形成二氧化碳雪花冷凍源,二氧化碳雪花冷凍源再經由第二噴嘴發射至病原處。Furthermore, carbon dioxide (CO 2 ), which is a source of refrigeration in the present embodiment, is delivered to the spout 4135 via the inner tube 4132, which controls the flow of carbon dioxide into the snowflake forming chamber 4134. The carbon dioxide forms a carbon dioxide snowflake freezing source in the snowflake forming cavity 4134. The plug ring 4133 prevents the carbon dioxide snowflake freezing source formed in the snowflake forming cavity 4134 from flowing back into the gap between the outer tube 4131 and the inner portion 4132. The carbon dioxide snowflake freezing source is then transferred to the second nozzle via the carbon dioxide snowflake delivery tube 411 and emitted by the second nozzle. Further, the carbon dioxide is a high-pressure liquid carbon dioxide. When the carbon dioxide is transferred to the carbon dioxide snow-forming element 413, the pressure is lowered and a carbon dioxide snowflake freezing source is formed in the carbon dioxide snow-forming element 413, and the carbon dioxide snowflake freezing source is emitted to the second nozzle. Pathogen.

再者,本發明所用之如圖5所示之二氧化碳雪花形成元件可具有另--不同之實施方式。如圖6所示,圖6係另一實施例之二氧化碳雪花形成元件之具通氣孔徑之二氧化碳雪花形成元件之內部構造示意圖。具通氣孔徑之二氧化碳雪花形成元件414係包含:一外管4141、一內管4142、一栓塞環4143、一雪花形成腔體4144、以及一噴口4145,而外管4141上係具有一通氣孔徑4146。其中,外管4141係用以保護內管4142,可作為支撐結構,而通氣孔徑4146之作用為導入空氣,使空氣流入,如此一來,可保持內視鏡鏡頭處保持能見度,減少雪花形成阻塞於出口處之機率,並於噴嘴處加速蒸發進而減少雪花粒徑大小。通氣孔徑4146之數目並無限制,外管4141係可目有一個或多個通氣孔徑4146。再者,通氣孔徑4146於本發明之內視鏡系統中的位置並不限定位於栓塞4143旁,係可位於外管4141上任何位置。此外,通氣孔徑4146大小可視本發明之內視鏡系統的需求而定,例如,若內視鏡鏡頭處對能見度需求極高,則可設置較多的通氣孔徑4146。再者,外管4141及內管4142具可撓性,因此,二氧化碳雪花形成元件414即可設置於亦具可撓性之內視鏡管中。Further, the carbon dioxide snowflake forming member shown in Fig. 5 used in the present invention may have another different embodiment. As shown in Fig. 6, Fig. 6 is a schematic view showing the internal structure of a carbon dioxide snowflake forming member having a ventilating aperture of a carbon dioxide snowflake forming member of another embodiment. The carbon dioxide snowflake forming element 414 having a venting aperture includes an outer tube 4141, an inner tube 4142, a plug ring 4143, a snowflake forming cavity 4144, and a spout 4145, and the outer tube 4141 has a venting aperture 4146. . The outer tube 4141 is used to protect the inner tube 4142, and can serve as a support structure, and the venting aperture 4146 functions to introduce air to allow air to flow in, thereby maintaining visibility at the endoscope lens and reducing snowflake formation obstruction. The probability at the exit, and accelerated evaporation at the nozzle to reduce the size of the snowflake. The number of venting apertures 4146 is not limited, and the outer tube 4141 can have one or more venting apertures 4146. Moreover, the position of the venting aperture 4146 in the endoscope system of the present invention is not limited to being located adjacent the plug 4143 and can be located anywhere on the outer tube 4141. In addition, the size of the venting aperture 4146 may depend on the needs of the endoscope system of the present invention. For example, if the visibility requirements at the endoscope lens are extremely high, more venting apertures 4146 may be provided. Furthermore, the outer tube 4141 and the inner tube 4142 are flexible, so that the carbon dioxide snowflake forming element 414 can be placed in an flexible endoscope tube.

此外,本實施例中做為冷凍源之二氧化碳(CO2 )則經由內管4142輸送至噴口4145,噴口4145係可控制二氧化碳進入雪花形成腔體4144之流量。而二氧化碳則於雪花形成腔體4144內形成二氧化碳雪花冷凍源。栓塞環4143則可防止形成於雪花形成腔體4144內之二氧化碳雪花冷凍源回流至外管4141及內4142之間的空隙。二氧化碳雪花冷凍源則再經由二氧化碳雪花輸送管411傳送至第二噴嘴,並由第二噴嘴發射而出。再者,二氧化碳係為高壓液態二氧化碳,當二氧化碳被傳送至二氧化碳雪花形成元件414時,其壓力下降並於二氧化碳雪花形成元件414中形成二氧化碳雪花冷凍源,二氧化碳雪花冷凍源再經由第二噴嘴發射至病原處。In addition, carbon dioxide (CO 2 ), which is a source of refrigeration in this embodiment, is delivered to the spout 4145 via the inner tube 4142, and the spout 4145 controls the flow of carbon dioxide into the snowflake forming cavity 4144. The carbon dioxide forms a carbon dioxide snowflake freezing source in the snowflake forming cavity 4144. The plug ring 4143 prevents the carbon dioxide snowflake freezing source formed in the snowflake forming cavity 4144 from flowing back into the gap between the outer tube 4141 and the inner 4142. The carbon dioxide snowflake freezing source is then transferred to the second nozzle via the carbon dioxide snowflake delivery tube 411 and emitted by the second nozzle. Furthermore, the carbon dioxide is a high pressure liquid carbon dioxide. When the carbon dioxide is delivered to the carbon dioxide snowflake forming element 414, the pressure drops and a carbon dioxide snowflake freezing source is formed in the carbon dioxide snowflake forming element 414, and the carbon dioxide snowflake freezing source is then emitted via the second nozzle. Pathogen.

再者,二氧化碳雪花形成元件之形狀係為直管形,或可為圓球形,其並無限定為何種型狀。此外,本實施例可藉由改變第二噴嘴之形態來發射不同型狀的二氧化碳雪花冷凍源,如此即可控制二氧化碳雪花的顆粒大小。若病源處之面積較大,則可控制本實施例之內視鏡系統發射較大顆粒之二氧化碳雪花冷凍源,而若病源處之面積較小,則可控制本實施例之內視鏡系統發射較小顆粒之二氧化碳雪花冷凍源,如此可減少冷凍源對病源處周圍正常組織或細胞的破壞。Further, the shape of the carbon dioxide snowflake forming member is a straight tube shape, or may be a spherical shape, which is not limited to what shape. In addition, in this embodiment, different shapes of carbon dioxide snowflake freezing sources can be emitted by changing the shape of the second nozzle, so that the particle size of the carbon dioxide snowflake can be controlled. If the area of the disease source is large, the endoscope system of the embodiment can control the carbon dioxide snowflake freezing source of larger particles, and if the area of the disease source is small, the emission of the endoscope system of the embodiment can be controlled. Smaller particles of carbon dioxide snowflake freezing source, which can reduce the damage of the freezing source to normal tissues or cells around the source.

實施例2係將實施例1中之以液態氮為冷凍源之冷凍裝置以二氧化碳雪花冷凍裝置取代之。二氧化碳雪花冷凍源之型態係為固態,冷凍源自第二噴嘴發射後可更準確的到達病源處而不致液散,且其冷凍速度快。再者,二氧化碳之取得容易,且成本相較於其他成份之冷凍源更低,更具經濟價值。再者,二氧化碳雪花亦具有止血的功能,非常適合用於各種手術上。In the second embodiment, the freezing device using the liquid nitrogen as the freezing source in the first embodiment is replaced by a carbon dioxide snow freezing device. The type of carbon dioxide snowflake freezing source is solid, and the freezing from the second nozzle can more accurately reach the source without causing liquid dispersion, and the freezing speed is fast. Moreover, carbon dioxide is easy to obtain, and the cost is lower than that of other components, and it is more economical. In addition, carbon dioxide snowflake also has a hemostatic function, which is very suitable for various operations.

本發明之內視鏡系統可適用於任何需要內視鏡系統做為輔助之手術,例如腸道手術、心肺繞道手術,或者可應用在無針式黏膜抬升注射技術中。其係結合無針注射、及冷涷治療之方式,俾能降低病患的痛楚及提高內視鏡手術或內視鏡檢查的品質。The endoscope system of the present invention can be applied to any surgery that requires an endoscopic system as an aid, such as bowel surgery, cardiopulmonary bypass surgery, or can be applied to needleless mucosal lift injection techniques. It is combined with needle-free injection and cold fistula treatment, which can reduce the pain of patients and improve the quality of endoscopic surgery or endoscopy.

上述實施例僅係為了方便說明而舉例而已,本發明所主張之權利範圍自應以申請專利範圍所述為準,而非僅限於上述實施例。The above-mentioned embodiments are merely examples for convenience of description, and the scope of the claims is intended to be limited to the above embodiments.

11...內視鏡裝置11. . . Endoscope device

12...無針式注射裝置12. . . Needleless injection device

13...冷凍裝置13. . . Freezer

14...病原處14. . . Pathogen

112‧‧‧照明元件112‧‧‧Lighting elements

121‧‧‧注射液供應元件121‧‧‧Injection supply components

122‧‧‧加壓元件122‧‧‧ Pressurized components

123‧‧‧注射液輸送管123‧‧‧Injection tube

131‧‧‧冷凍源輸送管131‧‧‧Frozen source delivery tube

132‧‧‧冷凍源供應元件132‧‧‧Frozen source supply components

113‧‧‧操作孔113‧‧‧Operation hole

111‧‧‧光學元件111‧‧‧Optical components

14‧‧‧病原處14‧‧‧Pathogen

15‧‧‧組織層15‧‧‧ organizational level

41‧‧‧二氧化碳雪花冷凍裝置41‧‧‧CO2 snowflake freezing device

411‧‧‧二氧化碳雪花輸送管411‧‧‧CO2 snowflake duct

412‧‧‧二氧化碳供應元件412‧‧‧Carbon supply components

413‧‧‧二氧化碳雪花形成元件413‧‧‧CO2 snowflake forming element

1231‧‧‧第一噴嘴1231‧‧‧First nozzle

1311‧‧‧第二噴嘴1311‧‧‧second nozzle

4131‧‧‧外管4131‧‧‧External management

4132‧‧‧內管4132‧‧‧Inner management

4133‧‧‧栓塞環4133‧‧‧embol ring

4134‧‧‧雪花形成腔體4134‧‧‧ Snowflake forming cavity

4135‧‧‧噴口4135‧‧‧ spout

414‧‧‧具通氣孔徑之二氧化碳雪花形成元件414‧‧‧Carbon dioxide forming elements with venting aperture

4146‧‧‧通氣孔徑4146‧‧‧Ventilation aperture

4141‧‧‧外管4141‧‧‧External management

4142‧‧‧內管4142‧‧‧Inner management

4143‧‧‧栓塞環4143‧‧‧Embed ring

4144‧‧‧雪花形成腔體4144‧‧‧ Snowflake forming cavity

4145‧‧‧噴口4145‧‧‧ spout

圖1係本發明第一實施例之內視鏡系統之示意圖。1 is a schematic view of an endoscope system according to a first embodiment of the present invention.

圖2係圖1中A部分之內視鏡裝置之放大圖。Figure 2 is an enlarged view of the endoscope device of Part A of Figure 1.

圖3係本發明之注射液噴射方式之時間/壓力關係示意圖。Fig. 3 is a view showing the time/pressure relationship of the injection method of the injection of the present invention.

圖4係本發明第二實施例之內視鏡系統之示意圖。Figure 4 is a schematic illustration of an endoscope system in accordance with a second embodiment of the present invention.

圖5係二氧化碳雪花形成元件之內部構造示意圖。Fig. 5 is a schematic view showing the internal structure of a carbon dioxide snowflake forming member.

圖6係另一實施例之二氧化碳雪花形成元件之具通氣孔徑之二氧化碳雪花形成元件之內部構造示意圖。Fig. 6 is a schematic view showing the internal structure of a carbon dioxide snowflake forming member having a ventilating aperture of a carbon dioxide snowflake forming member of another embodiment.

11...內視鏡裝置11. . . Endoscope device

12...無針式注射裝置12. . . Needleless injection device

13...冷凍裝置13. . . Freezer

121...注射液供應元件121. . . Injection supply component

122...加壓元件122. . . Pressurized component

123...注射液輸送管123. . . Injection tube

131...冷凍源輸送管131. . . Frozen source delivery tube

132...冷凍源供應元件132. . . Freezing source supply element

Claims (20)

一種內視鏡系統,包括:一內視鏡裝置,包含:一光學元件,係用以擷取一影像;一照明元件,係配置於該光學元件之一側;及至少一操作孔,係配置於該照明元件之一側;一無針式注射裝置,包含:一注射液供應元件,係儲存有一注射液於其內;一加壓元件,係連接至該注射液供應元件,並對該注射液加壓形成一高速注射液噴流;及一注射液輸送管,該注射液輸送管之一端設有一第一噴嘴,該第一噴嘴係穿入至該操作孔,該注射液輸送管之另一端係連接至該注射液供應元件;以及一冷凍裝置,包含:一冷凍源供應元件,係儲存有一冷凍源於其中;及一冷凍源輸送管,係與該冷凍源供應元件連接,該冷凍源輸送管之一端設有一第二噴嘴,該第二噴嘴係穿入至該操作孔。 An endoscope system includes: an endoscope device comprising: an optical component for capturing an image; an illumination component disposed on one side of the optical component; and at least one operation hole configured On one side of the illumination element; a needleless injection device comprising: an injection supply component for storing an injection solution therein; a pressurizing component coupled to the injection supply component and for the injection Pressurizing the liquid to form a jet of high-speed injection; and an injection pipe having a first nozzle at one end of the injection pipe, the first nozzle penetrating into the operation hole, and the other end of the injection pipe Connecting to the injection supply component; and a refrigeration device comprising: a refrigeration source supply component storing a refrigeration source therein; and a refrigeration source delivery pipe connected to the refrigeration source supply component, the refrigeration source conveying One end of the tube is provided with a second nozzle, and the second nozzle penetrates into the operation hole. 如申請專利範圍第1項所述之內視鏡系統,其中,該內視鏡裝置係尋找出一病原處之位置,該無針式注射裝置經由該第一噴嘴噴射一注射液至該病原處鄰近之一組織層上,以使該組織層抬升,該冷凍裝置經由該第二噴嘴噴射該冷凍源至該病原處。 The endoscope system according to claim 1, wherein the endoscope device finds a position of a pathogen, and the needle-free injection device ejects an injection solution to the pathogen via the first nozzle Adjacent to one of the tissue layers to lift the tissue layer, the freezing device sprays the freezing source to the pathogen via the second nozzle. 如申請專利範圍第2項所述之內視鏡系統,其中,該注射液係穿透該組織層之表面,並停留於該組織層內。 The endoscope system of claim 2, wherein the injection penetrates the surface of the tissue layer and resides in the tissue layer. 如申請專利範圍第2項所述之內視鏡系統,其中,該病原處係為一瘜肉、或一腫瘤。 The endoscope system according to claim 2, wherein the pathogen is a meat or a tumor. 如申請專利範圍第1項所述之內視鏡手術方法,其中,該加壓元件之加壓方式係為電加壓方式、或活塞加壓方式。 The endoscopic surgical method according to claim 1, wherein the pressurizing means of the pressurizing element is an electric pressurization method or a piston pressurization method. 如申請專利範圍第1項所述之內視鏡系統,其中,該注射液係為一具生物可相容性之溶液。 The endoscope system of claim 1, wherein the injection is a biocompatible solution. 如申請專利範圍第6項所述之內視鏡系統,其中,該具生物可相容性之溶液係選自由:甲基纖維素(Methylcellulose)、羥丙基甲基纖維素(hydroxypropyl methylcellulose)、褐藻膠、生理食鹽水、或甘油等所組成之群組。 The endoscope system according to claim 6, wherein the biocompatible solution is selected from the group consisting of: methylcellulose (meth), hydroxypropyl methylcellulose, A group consisting of alginate, physiological saline, or glycerin. 如申請專利範圍第1項所述之內視鏡系統,其中,該內視鏡裝置包含二操作孔,該第一噴嘴及該第二噴嘴係分別穿入至該二操作孔。 The endoscope system of claim 1, wherein the endoscope device comprises two operation holes, and the first nozzle and the second nozzle are respectively penetrated into the two operation holes. 如申請專利範圍第1項所述之內視鏡系統,其中,該冷凍源係為液態氮。 The endoscope system of claim 1, wherein the freezing source is liquid nitrogen. 如申請專利範圍第1項所述之內視鏡系統,其中,該冷凍裝置係為一二氧化碳雪花冷凍裝置,該冷凍源輸送管係為一二氧化碳雪花輸送管,該冷凍源供應元件係為二氧化碳供應元件,係儲存有二氧化碳於其中,該二 氧化碳雪花冷凍裝置更包括一二氧化碳雪花形成元件,係與該二氧化碳雪花輸送管連接。 The endoscope system according to claim 1, wherein the freezing device is a carbon dioxide snowflake freezing device, and the freezing source conveying pipe is a carbon dioxide snowflake conveying pipe, and the freezing source supplying component is a carbon dioxide supply. a component that stores carbon dioxide therein, the second The carbon oxide snowflake freezing device further comprises a carbon dioxide snowflake forming element connected to the carbon dioxide snowflake conveying pipe. 如申請專利範圍第10項所述之內視鏡系統,其中,該冷凍源係為一二氧化碳雪花冷凍源。 The endoscope system of claim 10, wherein the freezing source is a carbon dioxide snowflake freezing source. 如申請專利範圍第11項所述之內視鏡系統,其中,該二氧化碳雪花輸送管之另一端係連接至該二氧化碳雪花形成元件,該內視鏡裝置係尋找出一病原處之位置,該無針式注射裝置經由該第一噴嘴噴射一注射液至該病原處鄰近之組織層上,以使該組織層抬升,該二氧化碳雪花冷凍裝置經由該第二噴嘴發射該冷凍源至該病原處。 The endoscope system of claim 11, wherein the other end of the carbon dioxide snowflake tube is connected to the carbon dioxide snowflake forming element, and the endoscope device is to find a position of a pathogen, the absence The needle injection device injects an injection solution to the tissue layer adjacent to the pathogen via the first nozzle to lift the tissue layer, and the carbon dioxide snowflake freezing device transmits the freezing source to the pathogen via the second nozzle. 如申請專利範圍第10項所述之內視鏡系統,其中,該二氧化碳雪花形成元件之形狀係為直管形。 The endoscope system of claim 10, wherein the carbon dioxide snowflake forming element is in the shape of a straight tube. 如申請專利範圍第10項所述之內視鏡系統,其中,該二氧化碳雪花形成元件之形狀係為圓球形。 The endoscope system of claim 10, wherein the carbon dioxide snowflake forming element has a spherical shape. 如申請專利範圍第10項所述之內視鏡系統,其中,該二氧化碳係為高壓液態二氧化碳。 The endoscope system of claim 10, wherein the carbon dioxide is high pressure liquid carbon dioxide. 如申請專利範圍第1項所述之內視鏡系統,其中,該第一噴嘴噴射之該注射液之噴射壓力係介於70bar至150bar之間。 The endoscope system according to claim 1, wherein the injection pressure of the injection liquid sprayed by the first nozzle is between 70 and 150 bar. 如申請專利範圍第16項所述之內視鏡系統,其中,該第一噴嘴噴射之該注射液噴射至該組織層上之角度係介於20度至90度之間。 The endoscope system of claim 16, wherein the injection of the injection liquid sprayed onto the tissue layer by the first nozzle is between 20 degrees and 90 degrees. 如申請專利範圍第16項所述之內視鏡系統,其中,該組織層抬升之抬升高度係介於1mm至15mm之間。 The endoscope system of claim 16, wherein the lifting height of the tissue layer is between 1 mm and 15 mm. 如申請專利範圍第16項所述之內視鏡系統,其中,該組織層抬升之抬升時間係介於1分鐘至60分鐘之間。 The endoscope system of claim 16, wherein the lifting time of the tissue layer is between 1 minute and 60 minutes. 如申請專利範圍第11項所述之內視鏡系統,其中,該二氧化碳雪花冷凍源之型態係對應於該第二噴嘴之形態。 The endoscope system of claim 11, wherein the carbon dioxide snowflake freezing source is in a form corresponding to the second nozzle.
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090149712A1 (en) * 2004-11-27 2009-06-11 Erbe Elektromedizin Gmbh Device for mucosa resection
TW200946076A (en) * 2008-01-29 2009-11-16 Csa Medical Inc Cryosurgery system having unintegrated delivery and visualization apparatus
TW201105284A (en) * 2009-08-12 2011-02-16 Univ Nat Cheng Kung Needle-free tissue elevation system applicable to endoscope

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090149712A1 (en) * 2004-11-27 2009-06-11 Erbe Elektromedizin Gmbh Device for mucosa resection
TW200946076A (en) * 2008-01-29 2009-11-16 Csa Medical Inc Cryosurgery system having unintegrated delivery and visualization apparatus
TW201105284A (en) * 2009-08-12 2011-02-16 Univ Nat Cheng Kung Needle-free tissue elevation system applicable to endoscope

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