TWI383792B - Heated eyelid cleanser - Google Patents

Description

Heating eyelid cleaner

This application claims the benefit and priority of U.S. Provisional Patent Application Serial No. 61/132,593, filed on June 20, 2008. This application is a continuation-in-part of U.S. Patent Application Serial No. 11/592,684, filed on Nov. 3, 2006, which is incorporated herein by reference.

Eyelids are important for the health of the entire eye because they protect the eye from damage from close objects or from pollutants in the air, such as pollen, dust particles or other foreign objects. The eyelids contain a plurality of glands that contain lacrimal glands and meibomian glands that form a tear film that is critical to the health of the eye. When a person blinks, a new tear film is created and tears are distributed across the cornea to lubricate the surface of the eye. This blinking action also "clears" foreign objects from the eyes.

However, eyelids suffer from some ubiquitous but annoying problems, especially those who wear contact lenses. These problems can also lead to other more serious complications. Staphylococcal gingivitis (sputum inflammation) is a complication. Radonitis is a common chronic inflammation of the eyelids characterized by the appearance of squamous ridges at the edges of the eyelids. This condition can be caused by a root cause allergy or a bacterial infection associated with facial and scalp seborrhoea.

Often associated with blepharitis or secondary infections are bacterial infections on the skin surface of the eyelid margin, commonly known as mumps. Other such infections include external mumps, commonly referred to as stye, which are caused by the secretion of meibomian glands around the eyelashes along the fine oil particles of the eyelid margin. Stye is a red soft mass at the onset of the onset and is usually completely infected within three days. It may be accompanied by pain, redness and softness of the eyelid margin. Although stye often recurs, regular cleaning of the eyelid margin minimizes the incidence. The second problem is the meibomian gland cyst, which is an inflammation of the meibomian glands in the orbit. Mesenteric cysts usually grow slowly within 2 to 3 weeks, and although they usually do not cause pain, surgical intervention is required if left untreated.

Endophthalmitis is an intraocular infection that usually occurs after cataract surgery. The pathogen of postoperative endophthalmitis is usually a bacterium, which is usually Staphylococcus epidermidis.

Embodiments of the invention include: a heated eyelid cleaning device; a method for making a heated eyelid cleaning device; a method for cleaning an eyelid with a heated eyelid cleaning device; and a kit for treating an eyelid.

In an embodiment of the invention, a device for cleaning an eyelid comprises: an eyelid cleaning composition; an absorbent pad, wherein the pad is saturated with the eyelid cleaning composition; and a heating element, wherein the heating element is encapsulated In the absorbent pad.

In one embodiment, the eyelid cleaning composition comprises a foamable liquid. In one embodiment, the eyelid cleaning composition comprises a surfactant mixture comprising: 7-10% strength PEG-80 sorbitan laurate, sodium tridecyl ether sulfate (sodium) Trideceth sulfate), PEG-150 distearate, cocamidepropyl hydroxysultaine, lauroamphocarboxyglycinate and laureth-13 carboxylate Sodium laureth-13 carboxylate; PEG-15 tallow polyamine present at a concentration of 0.1-0.5%; at least one preservative present at a concentration of 0.1-0.5%, selected from the group consisting of quaternary ammonium salts-15 (Quaternium-15) and a group consisting of benzyl alcohol; and disodium edetate in the presence of 0.0-0.1% in aqueous solution.

In another embodiment of the invention, the eyelid cleaning composition comprises an eyelid cleaning agent. The cleaning agent is effective as an antibacterial agent when the eye is subjected to minimal irritation. The cleaning agent comprises polyhexamethylene biguanide (PHMB), 1,2-hexanediol, 1,2-octanediol, and a pH-stabilizing surfactant solution, which is effective to control the pH of the composition. There is an amount between 5.5 and 7.5. The use of a surfactant solution rather than the use of conventional pH adjusting agents to control pH results in less eye irritation of the composition. Further, the foaming ability of the surfactant solution contained in the composition enhances the cleaning ability of the composition.

In one embodiment, the pH stabilized surfactant solution comprises cocoa amphoteric diacetate disodium, polyoxyethylene 80 sorbitan monolaurate, decyl polyglucoside, and modified Ringer's (Ringer's) solution.

In another embodiment, the composition also comprises a humectant such as methyl gluceth-20, sorbitol, glycerol, ethylene glycol, propylene glycol, carboxylic acid esters, amino acids. , glycoside derivatives, urea, lactate, and pantothenic acid derivatives.

In an embodiment, the absorbent pad comprises a woven mat. In another embodiment, the woven mat may further include a first woven fabric sheet and a second woven fabric sheet. The first and second woven sheets are held together by an adhesive member. In one embodiment, the first and second woven panels are held together by stitching or Velcro. In an embodiment, the heating element can be located within the first and second woven sheets.

In one embodiment, the heating element further comprises: a first package containing a first chemical selected from the group consisting of calcium oxide, copper sulfate, water, butanediol, zinc, sodium aluminate citrate , kaolin, PEG 8, methyl glucose 20 ethylene oxide, hydroxypropyl cellulose, talc, acrylate copolymer, polyethylene, methyl cellulose, ethyl cellulose, BHT, EDTA tetrasodium, or ultramarine a second package comprising a second chemical selected from the group consisting of calcium oxide, copper sulfate, water, butanediol, zinc, sodium aluminate citrate, kaolin, PEG-8, methyl glucose 20 Ethylene oxide, hydroxypropyl cellulose, talc, acrylate copolymer, polyethylene, methyl cellulose, ethyl cellulose, BHT, EDTA tetrasodium, or ultramarine; and film, which is placed in the first Between the package and the second package.

The eyelid cleaning device can further include a member for splitting the film. In an embodiment, the member for splitting the film includes applying a twist, snap, bend, twist, bend, or other action.

In another embodiment, the member for splitting the film includes an actuator. The actuator can include at least one tip that includes a surface that is sharp enough to pierce the film without causing significant damage to the woven pad. In another embodiment, the actuator further includes one or more of the following: a button, an operating lever, a switch, or a bolt.

The member for splitting the film causes the first chemical to contact the second chemical, whereby an exothermic reaction occurs. The exothermic reaction heats the woven mat to a temperature ranging from about 80 °F to about 150 °F.

In an embodiment of the invention, the first or second woven fabric sheet may further comprise a flap, wherein the first or second woven fabric sheet is adapted to allow the woven mat to be inserted and removed. When the heating element is exposed to a heating member, the heating element can be configured to store thermal energy, including a microwave oven, a conventional oven, an oven, a stove, a laser, a lighter flame, or a blower. The heating element can be further configured to heat the woven mat for 3 to 7 minutes.

In another embodiment, a kit for treating an eyelid comprises: an eyelid cleaning composition comprising a surfactant mixture comprising: PEG-80 sorbitol at a concentration of 7-10% Dry laurate, sodium tridecyl sulfate, PEG-150 distearate, cocoamidopropyl hydroxy sulphonate betaine, lauryl ampho carboxylic acid glycinate and lauryl alcohol Sodium ether-13 carboxylate; PEG-15 tallow polyamine present at a concentration of 0.1-0.5%; at least one preservative present at a concentration of 0.1-0.5% selected from the group consisting of quaternary ammonium salts-15 and benzyl alcohol a group consisting of; disodium edetate present in an aqueous solution at a concentration of 0.0-0.1%; a woven mat which is pre-soaked by the eyelid cleaning composition; and a heating element. In an embodiment of the invention, the heating element is encapsulated within the woven mat.

In another embodiment, a kit for treating an eyelid includes: an eyelid cleaning composition comprising an eyelid cleaning agent; a woven pad pre-soaked by the eyelid cleaning agent; and a heating element .

In one embodiment, the eyelid cleaning agent comprises polyhexamethylene biguanide (PHMB), 1,2-hexanediol, 1,2-octanediol; and a pH-stabilizing surfactant solution, which is The pH of the composition is effectively controlled to be present between 5.5 and 7.5. In one embodiment, the pH stabilized surfactant solution comprises cocoa amphoteric diacetate disodium, polyoxyethylene 80 sorbitan monolaurate, decyl polyglucoside, and modified Ringer's (Ringer's) solution. In another embodiment, the composition also comprises a humectant such as methyl glucose-20 ethylene oxide, sorbitol, glycerin, ethylene glycol, propylene glycol, carboxylic acid esters, amino acids, glycoside derivatives, urea, Lactate, and a derivative of pantothenic acid.

In one embodiment of the invention, the heating element is encapsulated within the woven mat. In one or more embodiments, the heating element can be external to the woven mat. The heating element can include a sleeve or a heated or heated outer casing for heating the woven mat.

In another embodiment, a method for making a heated eyelid cleaning apparatus, comprising: providing an eyelid cleaning composition; providing a woven mat that can be wetted by the eyelid cleaning composition; and A heating element is encapsulated within the woven mat. Exemplary eyelid compositions have been previously described.

The woven mat can be pre-soaked by the eyelid cleaning composition. In another embodiment, the woven mat is only required to be saturated with the eyelid cleaning composition prior to use by the patient/consumer in the eyelid.

In another embodiment, a method for cleaning an eyelid comprises: heating an eyelid cleaning composition; and applying the heated eyelid cleaning composition to the eyelid. In one embodiment, the eyelid cleaning composition comprises a foamable liquid, the cleaning composition further comprising (a) an anionic surfactant; (b) a nonionic thickener and a softening agent; (c) An amphoteric surfactant; and (d) at least one preservative. In another embodiment, the eyelid cleaning composition comprises an eyelid cleaning agent comprising polyhexamethylene biguanide (PHMB), 1,2-hexanediol, 1,2-octanediol, and a pH. The stabilized surfactant solution is present in an amount effective to control the pH of the composition between 5.5 and 7.5.

Heating of the eyelid cleaning composition comprises heating the eyelid cleaning composition to a temperature range between 80 °F and 150 °F. In one embodiment, the eyelid cleaning composition is used to clean the eyelids for a period of between 240 seconds and 500 seconds. In another embodiment, the eyelid cleaning composition can remain on the eyelid without rinsing away.

Reference is now made to one or more embodiments of the invention.

FIG. 1 illustrates an embodiment of an eyelid cleaning device 100. A woven pad 105 includes a first bag 120 and a second bag 130. The first pack 120 and the second pack 130 contain chemical reactants that undergo an exothermic reaction with each other. The first package 120 and the second package 130 together form a heating element. The first pack 120 and the second pack 130 in the woven mat are separated by a film 110. The film 110 separating the first bag 120 and the second bag 130 can be designed to be manually cut by a user. After the film 110 is split, the chemical from the first pack 120 is released, in contact with the chemical from the second pack 130, thereby beginning the exothermic reaction. In an embodiment, the first package 120 can include a first chemical and the second package 130 can include a second chemical.

The film 110 can be split by a variety of components. In an embodiment, the means for splitting the film comprises an actuator. In an embodiment, the actuator can be a button that can be designed to pierce the film and allow chemicals from the first package 120 to contact and react with chemicals from the second package 130. In another embodiment, the actuator can include a button, lever, switch, or a bolt. In another embodiment, the film 110 can be broken by sufficiently twisting, snapping, bending, twisting, or flexing the film. However, it should be understood that the film may be cleaved by any suitable method as long as the reactants are allowed to react in an exothermic reaction.

The chemical substance contained in the first package 120 and the second package 130 for generating an exothermic chemical reaction may be selected from various exothermic reactants, and the reactants include calcium oxide, copper sulfate, water, butanediol, and zinc. , sodium citrate, kaolin, PEG 8, methyl glucose 20 ethylene oxide, hydroxypropyl cellulose, talc, acrylate copolymer, polyethylene, methyl cellulose, ethyl cellulose, BHT, EDTA tetrasodium and ultramarine. It will be appreciated that any chemical that will undergo an exothermic reaction when in contact with another chemical can be placed in the first pack 120 and the second pack 130.

The woven mat 105 can be saturated with an eyelid cleaning composition. In one embodiment, the eyelid cleaning composition is non-irritating to sensitive skin around the eyes and the ocular tissue itself, as appropriate, and has an antibacterial effect. In one embodiment, PHMB can be used as an effective antibacterial agent. Here, polyhexamethylene biguanide (PHMB) is a general term for polyhexamethylene biguanide, polyhexamethylene biguanide hydrochloride, and polyaminopropyl biguanide. In another embodiment, the mixture of 1,2-hexanediol and 1,2-octanediol and PHMB has a synergistic antibacterial effect, so the mixture can be used.

PHMB is most effective at pH ranges between 5.5 and 7.5. Therefore, by using a mixture of surfactants, it is expected that the pH of the eyelid cleaning composition is controlled within this range. It is also preferred that the eyelid cleaning composition of the present invention can achieve a foaming ability that facilitates physical promotion of cleaning the eyelids. Therefore, it is optional to control the pH of the eyelid cleaning composition within the effective range of PHMB and to provide a surfactant which physically cleans the foaming ability of the eyelids.

In another embodiment, the pH of the eyelid cleaning solution can be controlled to minimize irritation to the eye caused by an abnormal pH of the eyelid cleaning composition. The non-irritating formulation can have a near neutral or a pH of 7.0. The pH of many skin cleansers is not neutral and therefore does not reach or approach a pH of 7.0. To neutralize the pH of the composition, a pH adjusting agent can be used to adjust the pH. Examples of conventional pH adjusting agents include alkaline pH adjusting agents such as ammonia, monoalkylamines, dialkylamines, trialkylamines, monoalkanolamines, dialkanolamines, trialkanolamines, alkali metals, and Alkaline earth metal hydroxides (such as ammonia, sodium hydroxide, potassium hydroxide, lithium hydroxide, monoethanolamine, triethylamine, isopropylamine, diethanolamine, and triethanolamine), and acidic pH adjusters such as mineral acids and polycarboxylates Acids (such as hydrochloric acid, nitric acid, phosphoric acid, sulfuric acid, citric acid, glycolic acid, and lactic acid). However, some of the modulators themselves may cause irritation.

In one embodiment, the pH of the eyelid cleaning composition is controlled by a surfactant solution rather than by conventional pH adjusting agents. Surfactants can be less irritating to the eye than conventional pH adjusting agents. Suitable surfactants for use in the pH stabilized surfactant solution comprise amphoteric surfactants, anionic surfactants, and nonionic surfactants. Suitable amphoteric surfactants include, but are not limited to, alkyl dimethyl betaine, alkyl guanamine betaines, sultaines, and imidazoline amphiphiles. Suitable anionic surfactants include, but are not limited to, fatty alcohol sulfates, alpha-olefin sulfonates, sulfosuccinates, sarcosinates, phosphates, and carboxylates. Suitable nonionic surfactants include, but are not limited to, alkanolamines, ethoxylated amines, esters, alkoxylated alcohols, alkyl polyglycosides, amine oxides, sorbitan esters, and ethoxylates. .

In one embodiment, the pH stabilized surfactant solution comprises: cocoa amphoteric diacetate disodium, polyoxyethylene 80 sorbitan monolaurate, decyl polyglucoside, and modified Ringer Ringer's solution. Cocoon amphoteric diacetate disodium is an amphoteric surfactant. Polyoxyethylene 80 sorbitan monolaurate and decyl polyglucoside are nonionic surfactants. In another embodiment, when mixed, the eyelid cleaning composition comprises from about 0.1 to 25% by weight of disodium cocoa amphoteric diacetate, from 0.1 to 10% by weight of polyoxyethylene 80 sorbitan monolauric An acid ester, 0.2 to 10% by weight of decyl polyglucoside, and 60 to 98% by weight of a modified Ringer's solution.

In addition to reducing irritation, many surfactants have the added ability to create blistering which aids in the cleaning ability of the eyelid cleaning composition. To form the pH stabilized surfactant solution, one or more of the foam generating surfactants are first selected to provide the foaming ability of the eyelid cleaning composition. Suitable surfactants include: anionic, nonionic, and amphoteric surfactants. In one embodiment, polyoxyethylene 80 sorbitol monolaurate and alkyl glycoside are used as the foam generating surfactant.

In this embodiment, one or more additional surfactants may be added to the pH stabilized surfactant solution to compensate for the pH of the foam generating surfactant. In one embodiment, the pH of the foam generating surfactant can be determined to determine whether a pH compensating surfactant is to be added, and if desired, a pH compensating surfactant can be selected to control the pH of the solution. Need to be within range. For example, if the pH of the foam-producing surfactant is in the acidic range, i.e., less than 7.0, a pH-compensating surfactant in the alkaline range can be selected. Suitable pH-compensating surfactants include both sudsing and non-foaming surfactants, and the like further comprise: anionic, nonionic, and amphoteric surfactants. In one embodiment, the pH compensating surfactant can be disodium cocoamphodiacetate.

A mixture of surfactants can be added to the modified Ringer's solution. The modified Ringer's solution can be an isotonic electrolyte aqueous solution that is physiologically compatible with human tissue and can include sodium chloride, potassium chloride, calcium chloride, and water. In another embodiment, the modified Ringer's solution can be included in a surfactant solution to ensure that the eyelid cleaning composition does not remove moisture from body tissue due to osmosis.

The modified Ringer's solution includes: sodium chloride, potassium chloride, calcium chloride, and water. In another embodiment, the water used is purified water. The modified Ringer's solution may also include 0.05 to 1.2% by weight of sodium chloride, 0.005 to 0.5% by weight of potassium chloride, 0.005 to 0.5% by weight of calcium chloride, and water. In yet another embodiment, the modified Ringer's solution comprises about 0.7% by weight sodium chloride, about 0.03% by weight potassium chloride, about 0.033% by weight calcium chloride, and purified water.

In yet another embodiment, the eyelid cleaning composition can further comprise one or more humectants. A humectant is a chemical that prevents the loss of moisture from the epidermis. Moisturizers prevent moisture loss by forming a film on the skin to prevent moisture from evaporating from the skin. Alternatively, the humectant includes hygroscopic molecules that absorb moisture from the air into the skin. Suitable humectants include, but are not limited to, methyl glucose 20 ethylene oxide, sorbitol, glycerin, propylene glycol, carboxylic acid esters, amino acids, glycoside derivatives, urea, lactate, and pantothenic acid derivatives. Examples of pantothenic acid derivatives include: ubiquinol, D-ubiquinol, and D,L-ubiquinol.

In another embodiment, the eyelid cleaning composition also includes a foam stabilizer. A foam stabilizer is a chemical that extends the life of the foam. The foam stabilizer can be a polyethylene glycol ester of methyl glucose and a fatty acid. Suitable fatty acids include: oleic acid, stearic acid, lauric acid, octanoic acid, and citric acid. Suitably, the foam stabilizer can be PEG-120 methyl glucan dioleate.

In another embodiment, the eyelid cleaning composition comprises: polyhexamethylene biguanide, 1,2-hexanediol, 1,2-octanediol, D-ubiquinol, cocoa amphoteric diacetic acid Disodium, polyoxyethylene 80 sorbitan monolaurate, decyl polyglucoside, methyl glucose-20 ethylene oxide, and PEG-120 methyl glucose dioleate.

In another embodiment of the invention, the eyelid cleaning composition comprises: from about 0.02% to about 0.3% by weight PHMB, from about 0.05% to about 2.0% by weight 1,2-hexanediol, from about 0.05% to about 2.0% by weight of 1,2-octanediol, about 0.1% to about 25% by weight of disodium cocoa amphoacetate, about 0.1% to about 10% by weight of polyoxyethylene 80 sorbitan monolauric The acid ester, from about 0.2% to about 10% by weight of the decyl polyglucoside, and from about 60% to about 98% by weight of the modified Ringer's solution.

In still another embodiment of the present invention, the eyelid cleaning composition comprises: about 0.04% by weight of polyhexamethylene biguanide, about 0.2% by weight of 1,2-hexanediol, and about 0.2% by weight of 1, 2-octanediol, about 0.2% by weight of D-panenol, about 0.215% by weight of disodium cocoamphodiacetate, about 4.032% by weight of polyoxyethylene 80 sorbitan laurate, about 0.275% by weight of decyl polyglucoside, about 4.3% by weight of methyl glucose-20 ethylene oxide, about 0.6% by weight of PEG-120 methylglucose dioleate, about 87.985% by weight of modified forest Ringer's solution, and water.

In another embodiment, the mixture of surfactants comprises an aqueous solution of from about 7% by weight to about 10% by weight of an anionic surfactant, a nonionic thickener, a softener, and a mixture of amphoteric surfactants.

In yet another embodiment, the mixture of surfactants can include PEG-80 sorbitan laurate, sodium tridecyl sulfate, PEG-150 distearate, cocoamido Hydroxysulfonic acid betaine, lauryl amphocarboxylic acid glycinate, and sodium laureth-13 carboxylate. In still another embodiment, the eyelid cleaning composition may comprise: polyoxyethylene sorbitan fatty acid ester, PEG-80 sorbitan laurate, lauryl amphocarboxylic acid glycinate, and laurel Sodium alcohol alkoxide-13.

The eyelid cleaning composition can further comprise a PEG-15 tallow polyamine in a concentration range of from 0.1% to 0.5% by weight. This compound is a tertiary surfactant and softener. Sodium chloride can also be present in a concentration range of from about 0.6% to about 0.9%. In this embodiment, the pH of the eyelid cleaning composition can range from about 8.0 to about 8.5.

Preservatives can also be included in the eyelid cleaning composition. In one embodiment, the preservative can be a quaternium-15, a quaternary ammonium salt. This preservative can be used in a concentration range of from about 0.1% to about 0.5%. In another embodiment, benzyl alcohol can also be used as a preservative. In this embodiment, the concentration of benzyl alcohol can range from about 0.1% to about 0.5%.

In yet another embodiment, a chelating agent, such as disodium EDTA, can be included in the eyelid cleaning composition at a concentration ranging from about 0.01% to about 0.1%.

Zinc salts are astringents that cause skin tightening. The skin around the eye area is more sensitive than the skin in other areas. The inclusion of a zinc salt in the eyelid cleaning composition is undesirable because the astringency of the zinc salt causes the eyelid cleaning composition to produce greater irritation to the eyelid area. Thus in one embodiment, the eyelid cleaning composition comprises PHMB, 1,2-hexanediol, 1,2-octanediol, and a pH-stabilizing surfactant solution, but is also substantially free of zinc salts. Examples of the zinc salt include zinc acetate, zinc lactate, zinc gluconate, zinc citrate, zinc butyrate, and zinc stearate.

Referring to Figure 1, a woven pad 105 can be used to deliver the eyelid cleaning composition. The woven mat 105 can be comprised of any suitable woven fabric. In one embodiment, a suitable woven fabric can include the eyelid cleaning composition in the woven fabric weave. The selected woven fabric can have a textured surface sufficient to provide a suitable cleaning action for the eyelid cleaning composition on the patient's eyelids. However, the woven fabric remains sufficiently soft to not cause discomfort to the skin surface of the patient. In one embodiment, the woven mat may be comprised of a mixture of a matte material and a polypropylene woven fabric.

As shown in FIG. 2, in another embodiment of the eyelid cleaning device 200, the woven mat 205 may include two woven fabric sheets, a first woven fabric sheet 240 and a second woven fabric sheet 250. The two pieces of woven fabric can be held together by stitches 260 on both sides. A heating element 210 can be packaged within the first woven fabric sheet 240 and the second woven fabric sheet 250.

In one embodiment, the woven mats 105, 205 having the packaged heating elements are saturated with the eyelid cleaning composition during manufacture. The woven mats 105, 205 can then be sealed in a container to prevent evaporation of the eyelid cleaning composition. The sealable container comprises a box or a box. The package may be made of a suitable material comprising a plastic or metal foil material. The pre-soaked woven mats 105, 205 can also be used in individual packaging.

In another embodiment, the woven mats 105, 205 having the packaged heating elements can be saturated with the eyelid cleaning composition prior to use. The eyelid cleaning composition can be separately packaged from the woven mats 105, 205 and applied to the woven mats 105, 205 by a user. In an embodiment, the eyelid cleaning composition can be packaged in a bubble pump dispenser.

In an embodiment of the invention, the eyelid cleaning device 100, 200 can be heated prior to application to the eye area. Upon heating, the eyelid cleaning composition on the woven mat is also heated, which helps to increase the efficacy of the eyelid cleaning composition.

The heat transferred to the eyelid cleaning device 100, 200 and the eyelid cleaning composition is sufficient to bring the temperature of the eyelid cleaning composition to a temperature that helps to clean the eye area while keeping the temperature low enough to not scald the patient's skin or Causes discomfort. In one embodiment, the eyelid cleaning device 100, 200 can be heated to maintain the temperature of the eyelid cleaning composition within a range of from about 80 °F to about 150 °F.

In another embodiment, the eyelid cleaning device 100, 200 can retain heat for a sufficient amount of time to complete the cleaning process. The precise time required to clean the eyelids varies from person to person and can further depend on the severity of the patient's condition. In one embodiment, the eyelid cleaning device 100, 200 can retain heat for approximately 3 minutes to 7 minutes.

Referring to FIG. 2, in another embodiment of the eyelid cleaning device 200, a heating element 210 after external heating can be placed within the woven mat 205. In this embodiment, the woven mat 205 can include a flap (not shown) for insertion of the heating element 210. After the heating element 210 is encapsulated, the tab is closed. It will be appreciated that the heating element 210 can be packaged in the woven mat 205 in any suitable manner known in the art, including stitching 260 or Velcro.

The heating element 210 can be heated by any reasonable method, including heating with a microwave oven, a conventional oven, an oven, a stove, a laser, a lighter flame, or a blower. However, it should be understood that the heating member is not limited to the listed components and can be any viable member that generates heat.

3 represents another embodiment of an eyelid cleaning device 300 in which the woven mat 305 is heated by being placed in a heating or thermowell 310 for a specific period of time. The heating sleeve 310 can be heated by a heating device. In an embodiment, the heating sleeve 310 can be first heated, for example, in a microwave oven. The heating jacket 310 is heated until it stores sufficient thermal energy to heat the woven mat 305. Once the heating sleeve 310 is heated, the woven mat 305 can be placed therein such that heat can be transferred from the heating sleeve 310 to the woven mat 305, thereby heating the woven mat 305. In one embodiment, the woven mat is impregnated with one or more of the exemplary eyelid cleaning compositions previously described. The heated woven mat 305 can then be easily removed from the heating sleeve 310. The user can apply the heated woven mat 305 to the eye area. The woven mat 305 can be pre-soaked by the eyelid cleaning composition or the eyelid cleaning composition can be placed on the woven mat 305 when used by a user.

In an embodiment of the invention, the eyelid cleaning device 100, 200, 300 is used to clean the eyelids. The eyelid cleaning devices 100, 200, and 300 can be used for sterilization before eyelid surgery and various eyelid diseases, such as daily use for prevention of eyelid inflammation.

The eyelid cleaning composition can be mild enough that it remains on the eyelids after cleaning of the eyelids without rinsing. The eyelid cleaning composition is retained on the eyelids without rinsing away, which enhances the antimicrobial efficacy of the eyelid cleaning composition. In general, the longer the antimicrobial eyelid cleaning composition is in contact with the pathogen, the more pathogens it can kill.

While the invention has been described with reference to the embodiments of the embodiments of the invention Therefore, many modifications and variations of the present invention are intended to be included within the scope of the invention.

100. . . Eyelid cleaning device

105. . . Weaving mat

110. . . film

120. . . First package

130. . . Second package

200. . . Eyelid cleaning device

205. . . Weaving mat

210. . . Heating element

240. . . First woven fabric

250. . . Second woven fabric

260. . . Stitching

300. . . Eyelid cleaning device

305. . . Weaving mat

310. . . Heating casing

Figure 1 is an embodiment of the present invention;

Figure 2 is another embodiment of the present invention; and

Figure 3 is still another embodiment of the present invention.

100. . . Eyelid cleaning device

105. . . Weaving mat

110. . . film

120. . . First package

130. . . Second package

Claims (30)

A device for cleaning an eyelid, comprising: an eyelid cleaning composition comprising: polyhexamethylene biguanide; 1,2-hexanediol; 1,2-octanediol; and a pH-stabilizing surface active a solution present in an amount effective to control the pH of the composition between 5.5 and 7.5; an absorbent pad which is saturated with the eyelid cleaning composition; and a heating element wherein the heating element is encapsulated In the absorbent pad. The device of claim 1, wherein the eyelid cleaning composition is a foamable liquid, a cleaning agent, a gel, an ointment, a cream, a lotion or a paste. The device of claim 1, wherein the eyelid cleaning composition further comprises: a surfactant mixture comprising: 7-10% by weight of PEG-80 sorbitan laurate, tridecyl alcohol polyether sulfuric acid Sodium trideceth sulfate, PEG-150 distearate, cocamidepropyl hydroxysultaine, lauroamphocarboxyglycinate and laureth Sodium laureth-13 carboxylate; PEG-15 tallow polyamine present at a concentration of 0.1-0.5%; at least one preservative present at a concentration of 0.1-0.5%, selected from the group consisting of quaternary ammonium a group consisting of -15 (Quaternium-15) and benzyl alcohol; and disodium edetate in the presence of 0.0-0.1% in aqueous solution. The device of claim 1, wherein the pH-stabilizing surfactant solution is composed of one or more surfactants selected from the group consisting of amphoteric surfactants, anionic surfactants, and nonionic surfactants. group. The device of claim 4, wherein the amphoteric surfactants are selected from the group consisting of alkyl dimethyl betaine, alkyl guanamine betaine, sultaine, and imidazoline amphiphiles. The device of claim 4, wherein the anionic surfactant is selected from the group consisting of fatty alcohol sulfates, alpha-olefin sulfonates, sulfosuccinates, sarcosinates, phosphates, and Carboxylic acid ester. The device of claim 4, wherein the nonionic surfactants are selected from the group consisting of alkanolamines, ethoxylated amines, esters, alkoxylated alcohols, alkyl polyglycosides, amine oxidations , sorbitan ester, and ethoxylate. The device of claim 1, wherein the pH-stabilizing surfactant solution comprises: cocoa amphoteric diacetate disodium; polyoxyethylene 80 sorbitan monolaurate; thiol polyglucoside; and upgrading Ringer's solution. The device of claim 8, wherein the modified Ringer's solution comprises: sodium chloride; potassium chloride; calcium chloride; water. The device of claim 1, wherein the eyelid cleaning composition further comprises: D-ubiquinol; methyl glucose-20 ethylene oxide; and PEG-120 methyl glucose dioleate . The device of claim 1, wherein the eyelid cleaning composition further comprises one or more humectants. The device of claim 1, wherein the absorbent pad comprises a woven mat. The device of claim 12, wherein the woven mat further comprises a first woven fabric sheet and a second woven fabric sheet, the heating element being disposed within the first and second woven fabric sheets. The device of claim 13, wherein the woven mat further comprises an adhesive member for holding the first and second woven sheets together. The device of claim 1, wherein the heating element further comprises: a first package containing a first chemical selected from the group consisting of calcium oxide, copper sulfate, water, butanediol, zinc, aluminum citrate Sodium, kaolin, PEG 8, methyl glucose 20 ethylene oxide, hydroxypropyl cellulose, talc, acrylate copolymer, polyethylene, methyl cellulose, ethyl cellulose, BHT, EDTA tetrasodium, Or a group of green; a second package containing a second chemical selected from the group consisting of calcium oxide, copper sulfate, water, butanediol, zinc, sodium aluminate citrate, kaolin, PEG 8, methyl glucose 20 ethylene oxide, hydroxypropyl cellulose, talc, acrylate copolymer, polyethylene, methyl cellulose, Ethylcellulose, BHT, tetrasodium EDTA, or ultramarine; and a film disposed between the first pack and the second pack. The device of claim 15 further comprising a member for splitting the film. The device of claim 16, wherein the splitting member comprises applying a twist, snap, bend, twist, bend, or other action The device of claim 16, wherein the splitting member comprises an actuator. The device of claim 18, wherein the actuator comprises at least one tip comprising a surface that is sharp enough to pierce the film without causing significant damage to the woven pad. The device of claim 18, wherein the actuator further comprises one or more of the following: a button, a lever, a switch, or a bolt. The device of claim 16, wherein the film is split such that the first chemical contacts the second chemical, whereby an exothermic reaction occurs. The device of claim 21, wherein the exothermic reaction heats the woven mat to a temperature ranging from about 80 °F to about 150 °F. A kit for treating eyelids, comprising: an eyelid cleaning composition; a woven mat that is pre-soaked by the eyelid cleaning composition; and a member for providing thermal energy to the woven mat . The kit of claim 23, wherein the eyelid cleaning composition comprises: a surfactant mixture comprising: 7-10% by weight of PEG-80 sorbitan laurate, tridecyl alcohol polyether sulfuric acid Sodium, PEG-150 distearate, cocoamidopropyl hydroxy sulfonic acid betaine, month Citrate carboxylic acid glycinate and sodium laureth-13carboxylate; PEG-15 tallow polyamine present at a concentration of 0.1-0.5%; at least one preservative present at a concentration of 0.1-0.5% It is selected from the group consisting of quaternary ammonium salts-15 and benzyl alcohol; and disodium edetate in the presence of 0.0-0.1% in aqueous solution. The kit of claim 23, wherein the eyelid cleaning composition further comprises: polyhexamethylene biguanide; 1,2-hexanediol; 1,2-octanediol; and a pH-stabilized surfactant solution, It is present in an amount effective to control the pH of the composition between 5.5 and 7.5. The kit of claim 23, wherein the means for providing thermal energy further comprises a heating jacket. The kit of claim 23, wherein the means for providing thermal energy further comprises a heating element disposed within the woven mat. A method for manufacturing a heated eyelid cleaning device, comprising: supplying an eyelid cleaning composition; providing a woven mat suitable for containing the eyelid cleaning composition; and encapsulating a heating element on the woven fabric Inside the cloth mat. The method of claim 28, wherein the eyelid cleaning composition comprises: a surfactant mixture comprising: PEG-80 sorbitan laurate, sodium tridecyl sulfate, at a concentration of 7-10% PEG- 150 distearate, cocoamidopropyl hydroxy sulphonate betaine, lauric acid amphoteric carboxylic acid glycinate and sodium laureth-13 carboxylate; PEG present in a concentration of 0.1-0.5% -15 tallow polyamine; at least one preservative present at a concentration of 0.1-0.5%, selected from the group consisting of quaternary ammonium salts-15 and benzyl alcohol; and present in aqueous solution at a concentration of 0.0-0.1% Disodium edetate. The method of claim 28, wherein the eyelid cleaning composition comprises: polyhexamethylene biguanide; 1,2-hexanediol; 1,2-octanediol; and a pH-stabilizing surfactant solution, The pH of the composition is effectively controlled to be between 5.5 and 7.5.