TWI350750B - Compositions comprising cyclohexylamines and aminoadamantanes - Google Patents

Compositions comprising cyclohexylamines and aminoadamantanes

Info

Publication number
TWI350750B
TWI350750B TW093133869A TW93133869A TWI350750B TW I350750 B TWI350750 B TW I350750B TW 093133869 A TW093133869 A TW 093133869A TW 93133869 A TW93133869 A TW 93133869A TW I350750 B TWI350750 B TW I350750B
Authority
TW
Taiwan
Prior art keywords
aminoadamantanes
cyclohexylamines
compositions
Prior art date
Application number
TW093133869A
Other languages
English (en)
Other versions
TW200526195A (en
Inventor
Mahendra G Dedhiya
Shashank Mahashabde
Yan Yang
Anshu Goel
Erhard Seiller
Bernhard Hauptmeier
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34572981&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI350750(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of TW200526195A publication Critical patent/TW200526195A/zh
Application granted granted Critical
Publication of TWI350750B publication Critical patent/TWI350750B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW093133869A 2003-11-05 2004-11-05 Compositions comprising cyclohexylamines and aminoadamantanes TWI350750B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51798103P 2003-11-05 2003-11-05

Publications (2)

Publication Number Publication Date
TW200526195A TW200526195A (en) 2005-08-16
TWI350750B true TWI350750B (en) 2011-10-21

Family

ID=34572981

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093133869A TWI350750B (en) 2003-11-05 2004-11-05 Compositions comprising cyclohexylamines and aminoadamantanes

Country Status (19)

Country Link
US (4) US20070270500A1 (zh)
EP (2) EP2289489B1 (zh)
AR (1) AR046314A1 (zh)
AT (1) ATE504290T1 (zh)
AU (1) AU2004287489B9 (zh)
CA (1) CA2543865C (zh)
CL (1) CL2008000125A1 (zh)
CY (1) CY1111456T1 (zh)
DE (1) DE602004032164D1 (zh)
DK (1) DK1684715T3 (zh)
ES (2) ES2362581T3 (zh)
HR (1) HRP20110482T1 (zh)
IL (1) IL175623A (zh)
PL (1) PL1684715T3 (zh)
PT (1) PT1684715E (zh)
SI (1) SI1684715T1 (zh)
TW (1) TWI350750B (zh)
WO (1) WO2005044228A2 (zh)
ZA (1) ZA200603561B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0512263A (pt) * 2004-06-17 2008-02-26 Merz Pharma Gmbh & Co Kgaa formulações de liberação imediata de formas de dosagem oral de memantina
US20060002999A1 (en) * 2004-06-17 2006-01-05 Forest Laboratories, Inc. Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane
US20070060887A1 (en) * 2005-08-22 2007-03-15 Marsh David A Ophthalmic injector
TW200916091A (en) * 2007-06-08 2009-04-16 Merz Pharma Gmbh & Amp Co Kgaa Neramexane for the treatment of nystagmus
AR070025A1 (es) 2007-09-12 2010-03-10 Merz Pharma Gmbh & Co Kgaa Uso de derivados de 1-amino-alquilciclohexano para el tratamiento del tinnitus coclear y composicion farmaceutica
TW201006463A (en) * 2008-06-26 2010-02-16 Merz Pharma Gmbh & Co Kgaa Pharmaceutical compositions comprising aminocyclohexane derivatives
JP5385402B2 (ja) 2008-12-19 2014-01-08 メルツ・ファルマ・ゲゼルシヤフト・ミト・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト・アウフ・アクティーン 肥満細胞媒介疾患を治療するための１−アミノ−アルキルシクロヘキサン誘導体
TWI432188B (zh) 2008-12-19 2014-04-01 Merz Pharma Gmbh & Co Kgaa 供治療發炎性皮膚疾病之１－胺基－烷基環己烷衍生物類
KR20130087379A (ko) 2010-06-18 2013-08-06 메르츠 파마 게엠베하 운트 코. 카가아 1-아미노-알킬시클로헥산 유도체의 국소 사용을 위한 겔 제형

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA974518A (en) 1972-04-20 1975-09-16 Merz And Co. Procedure for the manufacture of 1,3,5 trisubstituted adamantan compounds
DE2856393C2 (de) 1978-12-27 1983-04-28 Merz + Co GmbH & Co, 6000 Frankfurt Arzneimittel zur Behandlung von Morbus Parkinson
US5506231A (en) 1989-03-31 1996-04-09 The Children's Medical Center Corporation Treatment of aids dementia, myelopathy and blindness
US5334618A (en) 1991-04-04 1994-08-02 The Children's Medical Center Corporation Method of preventing NMDA receptor-mediated neuronal damage
ATE94384T1 (de) 1989-04-14 1993-10-15 Merz & Co Gmbh & Co Verwendung von adamantan-derivaten zur praevention und behandlung der cerebralen ischaemie.
US5455279A (en) 1991-04-19 1995-10-03 The Children's Medical Center Corporation Regimen method of mediating neuronal damage using nitroglycerine
US5614560A (en) 1991-04-04 1997-03-25 Children's Medical Center Corporation Method of preventing NMDA receptor-mediated neuronal damage
ES2134804T3 (es) 1991-04-19 1999-10-16 Childrens Medical Center Uso de un compuesto generador de oxido nitrico para prevenir daño neuronal.
US6071966A (en) * 1997-06-30 2000-06-06 Merz + Co. Gmbh & Co. 1-amino-alkylcyclohexane NMDA receptor antagonists
HU226110B1 (en) 1997-06-30 2008-04-28 Merz Pharma Gmbh & Co Kgaa 1-amino-alkylcyclohexane nmda receptor antagonists, pharmaceutical compositions containing and their use
SE9901077D0 (sv) 1999-03-23 1999-03-23 Astra Ab Novel use
US6444702B1 (en) 2000-02-22 2002-09-03 Neuromolecular, Inc. Aminoadamantane derivatives as therapeutic agents
TW593223B (en) * 2000-06-20 2004-06-21 Merz Pharma Gmbh & Co Kgaa 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists
JP2004515477A (ja) * 2000-12-07 2004-05-27 ニューロモレキュラー インコーポレイテッド Ｎｍｄａレセプターアンタゴニストを用いて神経精神医学的障害を処置するための方法
US6828462B2 (en) * 2001-11-07 2004-12-07 Merz Pharma Gmbh & Co. Kgaa Unsaturated 1-amino-alkylcyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists
AU2003251993A1 (en) * 2002-07-19 2004-02-09 Inge Grundke-Iqbal NMDA RECEPTOR ANTAGONISTS AND THEIR USE IN INHIBITING ABNORMAL HYPERPHOSPHORYLATION OF MICROTUBULE ASSOCIATED PROTEIN tau
CN1794981A (zh) * 2003-05-27 2006-06-28 森林实验室公司 治疗抑郁症和其它情绪障碍的nmda受体拮抗剂和选择性5－羟色胺重摄取抑制剂的组合

Also Published As

Publication number Publication date
CA2543865C (en) 2012-09-04
ZA200603561B (en) 2007-07-25
AU2004287489A1 (en) 2005-05-19
US20140350114A1 (en) 2014-11-27
EP1684715B1 (en) 2011-04-06
DK1684715T3 (da) 2011-07-11
EP2289489B1 (en) 2014-07-16
PL1684715T3 (pl) 2011-09-30
ATE504290T1 (de) 2011-04-15
AU2004287489B9 (en) 2008-10-09
AR046314A1 (es) 2005-11-30
US20100035995A1 (en) 2010-02-11
ES2362581T3 (es) 2011-07-07
AU2004287489B2 (en) 2008-08-28
CA2543865A1 (en) 2005-05-19
EP2289489A3 (en) 2012-06-06
US20070270500A1 (en) 2007-11-22
HRP20110482T1 (hr) 2011-07-31
WO2005044228A3 (en) 2006-06-22
TW200526195A (en) 2005-08-16
EP2289489A2 (en) 2011-03-02
PT1684715E (pt) 2011-05-02
ES2507500T3 (es) 2014-10-15
EP1684715A2 (en) 2006-08-02
SI1684715T1 (sl) 2011-07-29
CL2008000125A1 (es) 2008-03-14
WO2005044228A2 (en) 2005-05-19
IL175623A (en) 2012-10-31
US20120238631A1 (en) 2012-09-20
CY1111456T1 (el) 2015-08-05
DE602004032164D1 (de) 2011-05-19

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees