1342780 » > 鼠尾草 5-500 ~~^^ 25 牛至香草辛料萃取物 25-1000 50 紐崔萊香芹 5-500 25 ，组崔萊香芽可向通路實業集團國際公司(Access Business — International LLC of Ada’ Michigan)獲得。除了上文所提及的水果、蔬菜和草 本成份，本膳食增補劑亦可包含其他成份。舉例來說，適用於本發明之組 成和製造方法的維生素可包含：維生素A、維生素B卜維生素B2、維生素 B6、維生素B12、於驗醯胺、泛酸、葉酸、生物素、膽驗、維生素c、維 • 生素D以及維生素e。以下盘里包含合適的維生素組態表。 表四 —_____維生素组態表 份成 --- -- 西印度櫻桃粉末中的維生素 C .劑量A，毫克/曰 20-100 舞Jf B,毫克/曰 60 抗壞血酸(C) 100-700 440 /3胡蘿蔔素中的維生素A 1000-10,000IU 7500IU 生物素 0.01-4 0.300 CalPan Gran中的泛酸 膽鹼 5-300 50 10-400 50 葉酸 0.01-10 0.8 肌醇 5-100 25 維生素E — 10-5000U 150IU 混合生育酚 — 5-300 50 菸鹼酸/菸鹼醯胺 5-300 40 維生素B6 10-100 15 核聽黃素(B2) 維生素B1 .— 」 1-100 12.75 1-100 11.25 11 0：\4^APM5W1$\PU^65-001H〇r1'Y^otin9).D〇t 1342780 4 醋酸鹽中的維4去A 100-10,000iu ' 2500IU ^ 維生素B12 0.01-50 0.045 維生素D3 10-2000IU 400IU —^ 酵母，standardized@(sDuree of 100%RDA Bs) 5-350 60 ----- 除了上述所列維生素，適用於本發明之組成和製造方法的礦物質可包 含··硼、鈣、鉻、銅、碘、鎂、錳、鉬、鉀、硒以及釩。亦可使用其它维 生素和碌物質。以下表互包含適合本發明之增補劑的礦物質組態表。 表五 礦物質组態表 份成 劑量A,毫克/曰 劑董B，毫克/日^' 鈣 100-2000 ""----- 750 鉻 0.01-5 0Λ2 銅 0.01-5 " ~^--- 2 碘 0.001-5 0.15 鎂 10-1000 300 ~~ 錳 1-20 '---〜 5 鉬 0.001-75 0.075 鉀 5-300 --—~~〜 80 硒 0.001-5 0.100 辞 1-50 —~~——〜 15 利用L的成份並選擇性地取用紐的成份，本發明的 增補劑可提供絕大部分（甚至超過）建議所說之每日所需求多種維生素和 擴物質赵和紅制若依上聰量每日絲時料增補劑的效 力’係以上列之維生素和礦物質所占每日需求量的百分比表示。 iL<S. 12 13427801342780 » > Sage 5-500 ~~^^ 25 Oregano Herb Extract 25-1000 50 Nutrilite Parsley 5-500 25, Group Cui Lai Xiang Bu can be to Access Industrial Group International (Access Business — International LLC of Ada' Michigan). In addition to the fruits, vegetables and herbal ingredients mentioned above, this dietary supplement may also contain other ingredients. For example, vitamins suitable for use in the compositions and methods of the present invention may comprise: vitamin A, vitamin B, vitamin B2, vitamin B6, vitamin B12, prodecylamine, pantothenic acid, folic acid, biotin, biliary test, vitamin C. , Vitamin D and vitamin E. The following table contains the appropriate vitamin configuration table. Table 4 - _____ Vitamin configuration table into --- -- Vitamin C in West Indian cherry powder. Dosage A, mg / 曰 20-100 Dance Jf B, mg / 曰 60 Ascorbic acid (C) 100-700 440 Vitamin A in /3 carotene 1000-10,000 IU 7500 IU Biotin 0.01-4 0.300 Pantothenic acid choline in CalPan Gran 5-300 50 10-400 50 Folic acid 0.01-10 0.8 Inositol 5-100 25 Vitamin E 10- 5000U 150IU mixed tocopherol - 5-300 50 nicotinic acid / nicotinamide 5-300 40 vitamin B6 10-100 15 nuclear hearing flavin (B2) vitamin B1 .-" 1-100 12.75 1-100 11.25 11 0 :\4^APM5W1$\PU^65-001H〇r1'Y^otin9).D〇t 1342780 4 Vitamin 4 in acetate to A 100-10,000iu ' 2500IU ^ Vitamin B12 0.01-50 0.045 Vitamin D3 10- 2000 IU 400 IU —^ Yeast, standardized@(sDuree of 100% RDA Bs) 5-350 60 ----- In addition to the vitamins listed above, the minerals suitable for the composition and manufacturing method of the present invention may contain boron and calcium. , chromium, copper, iodine, magnesium, manganese, molybdenum, potassium, selenium and vanadium. Other vitamins and substances can also be used. The following tables contain, among each other, a mineral configuration table suitable for the supplement of the present invention. Table 5 Minerals configuration table into dose A, mg / sputum Dong B, mg / day ^ ' Calcium 100-2000 ""----- 750 Chromium 0.01-5 0Λ2 Copper 0.01-5 " ~ ^--- 2 Iodine 0.001-5 0.15 Magnesium 10-1000 300 ~~ Manganese 1-20 '---~ 5 Molybdenum 0.001-75 0.075 Potassium 5-300 ---~~~ 80 Selenium 0.001-5 0.100 -50 —~~——~ 15 Using the ingredients of L and selectively taking the ingredients of the New Zealand, the supplement of the present invention can provide most (or even exceed) the recommended daily multivitamins and expanded substances. Zhao and Hong's system is based on the percentage of daily demand for vitamins and minerals listed above. iL<S. 12 1342780
' I f—i I. · 胺苯甲酸。 本發明的膳食增補劑，可以用任何可被接受的藥劑形式來配製，如各 個水果濃縮物、蔬菜濃縮物、藥草濃縮物、植物化學物質、維生素、礦物 質和其它營養素，包括其鹽類。增補劑可以配製成旋劑、粉末、凝膠或是 液體(在揭示於此的文件中，本發明所謂Γ錠劑」指的是任何形式之固體口 服劑，包含但不受限於贫、橢圓旋、膠囊、粉末等等）。膳食增補劑可配置 成粉末，舉例來說，以便與可食用的液體混合如牛奶、果汁、水或是可食 用的凝膠或糖漿，以便混入其它可食用的液體或食品裡頭β本膳食增補劑 也可以用其它食品或液體來配製，提供預先測量好之補充食品，例如單一 份量棒。調味品、黏合劑、蛋白質、複合碳水化合物，以及類以物均可依 需要添加》 依本發明的觀點’膳食增補劑可以用三個獨立的錠劑施用，每天兩回； 然而此膳食增補劑可能依需求以其它型態或單位劑量供給。 以下範例說明但並非意欲要限制本發明的膳食增補劑。 範例一 調理這三片錠劑來提供：a)水果、蔬菜和藥草成份；b)維生素；c)礦物 質。第一旋劑包含盘二〜左之水果、蔬菜和藥草成份。其個別成份之數量是 表格中所列劑量B數量的一半，因為表中數量是在2個錠劑裡的份量。第 一鍵劑包含載趙(carriers)和其他壓片助劑(tableting aids)，如二氧化石夕、氧化 φ 鎮、碳酸鈣、交聯羧曱基纖維素鈉、微晶纖維素和硬脂酸鎂，其份量如熟 悉本技藝者所知可因需要而變更。 第二錠包含表里之維生素。在此錠中，其個別成份之數量是表格中列 出數量的一半，因為表中數量是兩個錠劑的份量。第二錠劑也可包含載體 (carriers)和其他壓片助劑(tableting aids)，如微晶纖維素、碳酸鈣、交聯羧甲 基纖維素鈉、硬脂酸鎂和二氧化矽。 第三錠包含表互之礦物質。在此錠中，其個別成份之數量是表格中列 .出數量的一半，因為表中數量是兩個錠劑的份量。第三錠劑亦可包含載體 (carriers)和其他壓片助劑(tabieting aids)，如微晶纖維素、碳酸奸、交聯羧甲 基纖維素鈉、硬脂酸鎂和二氧化矽。 1342780 I * 除了以上所說，還能增進血毁和全身的抗氧化劑含量。 研究中這^受試者，從18〜80歲的健康男性和女性，每周攝取低於12 種《建議食品清單》t所介紹的食品。這些受試者是依飲食習慣問卷和「建 議食品評分」（RecommendedFoods Score, RFS)。RFS由23種食物組成， 其中14種是水果和蔬菜’據研究指出這些食物的每周攝食量和減少死亡率 有關連。己在一項對於42,254位婦女的同齡族群研究中被證實。比較 平均為16.0(最高四分位數)和rfs為6·4(最低四分位數)兩組受試者，總因 死亡率的相對風險為0.69。最高四分位數和最低四分位數兩分組相比前 者所攝食明顯較多的成份有：卡路里(131%)、纖維(200%)、維生素c(23〇%)、 葉酸(181%)、可轉化成維生素A的類胡蘿蔔素(253%)。 臨床研究包含120位受試者為期六周的雙盲研究(也就是受試者和研究 者均不知情在這六周試驗期中，受試者被分配攝取本研究產品三錠每 天兩次，分別和早、晚餐一起服用。受試者所服用的是建議劑量的D〇uWeχ 2005或安慰劑》受試者將接受抽血和尿液樣本檢驗，並做出以下分析報告： 總多酚數、血漿氧自由基吸收量（ORAC,OxygenRadicalAbsorption Capacity)、CP450酵素誘發、細胞質分裂塊檢驗、細胞慧星試驗、生物能量 報告、尿液膽汁酸、B6、B12、葉酸、維生素c、高半胱胺酸、α和r生育 酚、召胡蘿蔔素、C-反應蛋白和尿液8-epi前列腺素F2a，以上分別測得其 基準值並在進行研究後兩周、四周以及六周檢驗。本饍食增補物過人之處 φ 以及其功效可依下述的度量測出··血漿中的維生素、礦物質和植物化學成 份之濃度；血漿中以及全身的抗氧化劑含量；解毒能力；細胞能量動力； 基因體穩定度；其他風險因素與主觀影響效果。 預期研究結果可顯示出攝取六周的增補劑之後，受試者血漿中之 7生育酚、Β12、Β6、葉酸鹽類、維生素C和其它抗氧化劑的濃度均顯著 增加’這就顯示出髏内抗氧化劑的數量增加，此現象特別與飲食中維生素、 營養素和植物化學成份缺乏症的改善有關，並(或)與自由基損害的減少有 .關。 以上描述為此發明的較佳實施例。依後文之申請專利範圍所定義，無 須違背此發明的精神及較寬廣觀點即可做各種不同變更及變化，申請專利 17 1342780 丨 1 • * j 範圍應依包含均等論在内的專利法的原則解釋。在申請專利範圍中任何元 件若是以單數表示，例如「一個」、「所稱」、「所謂」，都不應解釋為該元件 僅限於單數。' I f—i I. · Amin benzoic acid. The dietary supplement of the present invention may be formulated in any acceptable form, such as individual fruit concentrates, vegetable concentrates, herbal concentrates, phytochemicals, vitamins, minerals, and other nutrients, including salts thereof. The supplement may be formulated as a blister, powder, gel or liquid (in the document disclosed herein, the so-called bismuth tablet of the present invention) refers to any form of solid oral agent, including but not limited to poor, Elliptical spin, capsule, powder, etc.). The dietary supplement may be formulated as a powder, for example, to be mixed with an edible liquid such as milk, fruit juice, water or an edible gel or syrup for incorporation into other edible liquids or foods. It can also be formulated with other foods or liquids to provide pre-measured supplements, such as a single stick. Condiments, binders, proteins, complex carbohydrates, and the like can be added as needed. According to the present invention, a dietary supplement can be administered in three separate lozenges twice a day; however, this dietary supplement It may be supplied in other types or unit doses as needed. The following examples illustrate but are not intended to limit the dietary supplements of the present invention. Example 1 These three tablets are conditioned to provide: a) fruit, vegetable and herb ingredients; b) vitamins; c) minerals. The first blowing agent comprises the ingredients of the fruits 2, 2 and the left, fruits, vegetables and herbs. The number of individual ingredients is half the amount of dose B listed in the table, since the quantity in the table is the amount in 2 tablets. The first bond comprises carriers and other tableting aids such as dioxide, oxidized φ, calcium carbonate, croscarmellose sodium, microcrystalline cellulose and stearic acid. Magnesium sulphate, the amount of which is known to those skilled in the art, can be varied as needed. The second ingot contains the vitamins in the table. In this ingot, the number of individual components is half that listed in the table because the amount in the table is the amount of two tablets. The second tablet may also contain carriers and other tableting aids such as microcrystalline cellulose, calcium carbonate, croscarmellose sodium, magnesium stearate and cerium oxide. The third ingot contains minerals of the table. In this ingot, the number of individual components is half the amount listed in the table, because the quantity in the table is the amount of two tablets. The third tablet may also contain carriers and other tabieting aids such as microcrystalline cellulose, carbonic acid, croscarmellose sodium, magnesium stearate and cerium oxide. 1342780 I * In addition to the above, it also increases blood sugar and systemic antioxidant levels. In the study, the subjects, from healthy men and women aged 18 to 80, received less than 12 foods described in the Recommended Food List t. These subjects were in accordance with the dietary habits questionnaire and the "Recommended Foods Score" (RFS). The RFS consists of 23 foods, 14 of which are fruits and vegetables. According to research, the weekly food intake and mortality reduction of these foods are related. It has been confirmed in a peer-reviewed study of 42,254 women. Comparing the average of 16.0 (highest quartile) and rfs to 6.4 (lowest quartile), the relative risk of total mortality was 0.69. The highest quartile and the lowest quartile were significantly more ingested than the former: calories (131%), fiber (200%), vitamin c (23%), folic acid (181%) Carotenoids (253%) that can be converted to vitamin A. The clinical study included a six-week double-blind study of 120 subjects (ie, subjects and investigators were unaware of the fact that during the six-week trial period, subjects were assigned two ingots of the study product twice daily, respectively Take it with breakfast and dinner. Subjects are taking the recommended dose of D〇uWeχ 2005 or placebo. Subjects will be tested for blood and urine samples and will report the following: Total polyphenols, Plasma oxygen free radical absorption (ORAC, Oxygen Radad Absorption Capacity), CP450 enzyme induction, cytokinesis block test, cell comet assay, bioenergy report, urine bile acid, B6, B12, folic acid, vitamin C, homocysteine , α and r tocopherols, carotenoids, C-reactive protein and urine 8-epi prostaglandin F2a, the above benchmark values were measured and tested two weeks, four weeks and six weeks after the study. The superiority φ and its efficacy can be measured by the following measures: · the concentration of vitamins, minerals and phytochemicals in plasma; the antioxidant content in plasma and throughout the body; detoxification ability; Cellular energy kinetics; genomic stability; other risk factors and subjective effects. Expected results can show 7 tocopherols, sputum 12, sputum 6, folates, vitamins in the plasma of subjects after 6 weeks of supplementation. The concentration of C and other antioxidants increased significantly'. This shows an increase in the amount of antioxidants in the sputum, which is particularly associated with improved vitamins, nutrients and phytochemical deficiencies in the diet, and/or with free radical damage. The above description is a preferred embodiment of the invention. Various modifications and variations can be made without departing from the spirit and scope of the invention, as claimed in the appended claims. Patent application 17 1342780丨1 • * j The scope shall be interpreted in accordance with the principles of the patent law including the theory of equality. Any component in the scope of the patent application shall be in the singular, such as "one", "called", "so-called", and shall not be construed. This component is limited to the singular.
0：\ 4^f>PtAPu065\a)16\PW)6S-00l^(0ri-Y¥〇nn€).D〇c0:\ 4^f>PtAPu065\a)16\PW)6S-00l^(0ri-Y¥〇nn€).D〇c