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The present invention is directed to sulfuric acid mono-[3-({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenyl]ester a metabolite of the 5HT2A antagonist (+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol and a processes for its preparation and its use in the treatment for a number of disease states.
TW89114195A1999-07-162000-08-28A61p 9/00 200601 a i htw
TWI265924B
(en)
COMBINATIONS OF PAROXETINE AND 4- (S) - (4-ACETYL-PIPERAZIN-1-YL) -2- (R) - (4-FLUORO-2-METHYL-PHENYL) -PIPERIDINE-1-CARBOXYLIC ACID [1 - (R) - (3,5-BIS-TRIFLUOROMETHYL-PHENYL) -ETHYL] -METHYLAMIDE FOR THE TREATMENT OF DEPRESSION AND / OR ANXIETY
Use of (+)-alfa-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)-ethyl]-4-piperidinemethanol for producing pharmaceutical compositions suitable for treatment depressive disorders and bipolar disorders
Process for producing 4-{4-[4-(hydroxy-diphenyl)-1-piperidinyl]-1-hydroxy-butyl}-alpha-alpha-dimethyl-phenyl-acetic.acid and phosphorylized derivatives thereof
Esters of (+) - alpha (2,3-dimethoxyphenyl) -1- [2- (4-fluorophenyl) ethyl] -4-piperidinemethanol, process for their preparation, use and pharmaceutical composition
Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one, process for their preparation and pharmaceutical compositions containing them
Process for the racemisation of 1-benzyl-4-(4-fluorophenyl)-3-hydroxymethyl-1,2,3,6-tetrahydropyridine to be used as intermediate in the synthesis of paroxetine