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Priority claimed from US09/624,003external-prioritypatent/US6312708B1/en
Application filed by Allergan Sales LlcfiledCriticalAllergan Sales Llc
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Publication of TWI255717BpublicationCriticalpatent/TWI255717B/en
Medicines That Contain Protein Lipid Enzymes And Other Medicines
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Abstract
A controlled release system for multiphasic, in vivo release of therapeutic amounts of botulinum toxin in a human patient over a prolonged period of time. The controlled release system can comprise a plurality of botulinum toxin incorporating polymeric microspheres.
Use of (+)-tramadol, o-demethyltramadol or (+)-o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol or (+)-o-desmethyl-n-mono-desmethyl-tramadol for treating urinary incontinence