TWI253923B - Noninvasive sphygmus measurement method and system with constant pressure for extremity - Google Patents

Noninvasive sphygmus measurement method and system with constant pressure for extremity Download PDF

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TWI253923B
TWI253923B TW093136192A TW93136192A TWI253923B TW I253923 B TWI253923 B TW I253923B TW 093136192 A TW093136192 A TW 093136192A TW 93136192 A TW93136192 A TW 93136192A TW I253923 B TWI253923 B TW I253923B
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pressure
pulse
constant
value
limb
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TW093136192A
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TW200616582A (en
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Hen-Hong Chang
Kang-Ping Lin
Wen-Chen Lin
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Hen-Hong Chang
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Priority to US11/126,612 priority patent/US20060111638A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7242—Details of waveform analysis using integration

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention is related to a noninvasive sphygmus measurement system with constant pressure for extremity, and the constant pressure is modulated among 30 to 120 mmHg. There are an auto-mode and a manual mode for measurement algorithm. The auto-mode completes measurement and recording processes automatically during 2 minutes and pressurizes the system from low pressure (30 mmHg) to high pressure (120 mmHg) with 10 mmHg gradient every 5 seconds while the manual mode completes measurement and recording processes during a long time under user's setting. Moreover, by a post-treatment of the system, the recording obtains continuous sphygmus signal, continuous sphygmus differential signal, and continuous sphygmus integral signal for evaluation and monitoring of diagnosis by feeling the pulse of Chinese medicine, cardio-physiology and circulatory system.

Description

1253923 九、發明說明： 【發明所屬之技術領域】 本發明係關於一種中醫脈診儀器，藉由非侵入式電子診斷 儀器所測得之脈壓參數，不但方便醫院未來建立患者個人的電 子病歷，同時可以提供醫師在臨床上長期監測及生理分析之 用0 【先前技術】 隨著生醫科技的進步，對於生命體的血壓量測已由早期的 侵入式量測發展至現今之非侵入式量測。如第1圖所示，係傳 統非侵入式量測裝置的系統方塊圖。主要區分為類比電路10 及數位電路12兩大類。類比電路1 〇部份包含：壓力感測器 1〇〇、前置放大器102、高通濾波器1〇4、低通濾波器1〇6、增 益控制器108。數位電路12部份則包含：類比/數位轉換電路 120、微處理器122、繪圖型液晶顯示器124、加壓馬達及 洩氣閥128。 貫際上，中醫號脈方式乃是透過醫者手指之指腹，藉由施 予不同程度之壓力，並以自身觸感來描述也管的反應狀二，進 而綜合所有訊息以輔助病證之診斷。此方式最為困難之地 ^於醫者所施傾力大小無法定量且難以客觀紀錄、，然而 則在市面上之傳統脈診儀H，大多係採以單點 J直⑽單-橈動脈血管進行量測，其量測之操作 田費k費力’因此’本發明藉以利用傳統 （ :續的便利性’採以刚充氣之設計，並以; 脈診之儀器’更可以提供醫師在臨床上監測連續脈 1253923 途0 【發明内容】 ^發明之目的’主要係發展—套於不同 了連、、、❿雜壓訊號之量 ^ ([力狀心下， 使用浮舉、中霖A 、〗儀σσ精以杈擬中醫師在把脈時所 理功能監測^輔μ /料，以提供相關之中醫診斷、心血管生 輔助臨床診斷之應用。 壓訊i二的:本發明提供-種在四肢恆壓施壓之脈 制一壓脈袋jl連‘錢，其特徵係能長時L定之壓力控 法極易喝置測—受測者之四肢動脈的脈壓訊號。該方 體程式的方式實施，程式主體可區分為自動與 測，发種里測模式。自動模式採以10個定氣恆壓下自動量 ^ /、要目的為快速記錄出受測者脈壓訊號。手動模式即可 、了，使用者任意調整施加壓力值為量測之方式，其目的在於針 對文測者之收縮壓、平均壓及舒張壓立即長時間量測連續脈波 訊號，並可以紀錄儲存與分析。 、 ――為使熟悉該項技藝人士瞭解本發明之目的、特徵及功效， 茲藉由下述具體實施例，並配合所附之圖式，對本發明詳加說 明如后： w 【實施方式】 第2圖係本發明之脈壓訊號量測系統的具體架構圖。主要 係由壓脈袋20、主機電路22、顯示裝置24、儲存裝置26所 組成。其中顯示裝置24通常採用一繪圖型液晶顯示器，用以 顯不包含即時脈壓訊號、微分訊號、積分訊號、心跳頻率、及 1253923 參數值，並接著判斷步驟406係是否在該初始壓力值（Th)下 為維持所設定之時間^本貫施例設定之時間為5秒，如果為否 (False)，則回到步驟404 ;如果判別結果為是（True)，則進 入判斷步驟408，判別初始壓力值（Th)是否達到一最大壓力 值（Pmax )，該最大壓力值（Pmax )於本實施例之預設值為 120mmHg，如果為否（False)，則進入步驟410啟動力口壓馬達 30，將該壓力設定值（Po)增加一增值壓力值（Pup)後停止 運作（該增值壓力值（Pup)於本實施例之預設值為lOmmHg)， 並回到步驟400,如果判別結果為是（True)，則進入步驟409， 係開啟洩氣閥36以對壓脈袋20進行快速降壓直至OmmHg ; 以上步驟皆屬於本發明方法之自動模式，如第4A圖所示，其 目的係用以量測出受測者在不同程度壓力施壓下之脈壓變 化’作為手動模式量測的參考指標。 此後，本發明之量測系統將進入手動模式，如第4B圖所 示。步驟412係藉由加壓馬達30對壓脈袋20内施加至一恆定 壓力值（Ps);步驟414係判別該恆定壓力值（Ps)是否低於 一壓力下限值（Pslow )，如果為是（True )，則進入步驟416， 啟動加壓馬達30以對壓脈袋20進行加壓，於加壓後停止該加 壓馬達30後進入步驟414，如果為否（False )，則直接進行步 驟418 ;步驟418係判別該恆定壓力值（Ps)是否高於一壓力 上限值（Pshigh)，如果為是（True)，則進入至步驟420，開 啟洩氣閥36以對壓脈袋20進行降壓，並於降壓後進入步驟 418，如果為否（False)，則直接進行步驟422 ;步驟422係壓 力感測器200量測出受測者之脈壓訊號，以計算出脈壓訊號之 微分訊號及積分訊號；最後步驟424係設定是否需重新設定恆 定壓力值（Ps)，若是，則可再回到步驟412反覆量測之，若 否，則可到下一步驟結束。 1253923 依據本發明之手動模式，少驟414及步驟418可以達到控 制壓脈袋20的充氣壓力始終維持連續長時間恆定壓力之效 果，其中步驟414之壓力下限值略小於該恆定壓力值（Ps)， 而步驟418之壓力上限值則略大於該恆定壓力值（Ps)，而該 恆定壓力值（Ps)我們可以經由手動設定之，其壓力設定範圍 為5〜180mmHg。此後，經過步驟422運算式，最後計算出對 應的生理參數值。 茲歸納本發明之特點如后： •本發明方法極易以撰寫韌體的方式實施，程式主體區分為自 動與手動兩種模式，在自動模式係以自動控制方式完成量測並 紀錄之；手動方面可依照使用者自行設定其施壓之壓力以進行 長時間監測及紀錄。 •本發明可以結合如Compact Flash Card( CF卡）或Smart Media1253923 IX. Description of the invention: [Technical field of the invention] The present invention relates to a pulse diagnosis instrument for a traditional Chinese medicine, which is not only convenient for the hospital to establish an electronic medical record of a patient in the future, but also a pulse pressure parameter measured by a non-invasive electronic diagnostic apparatus. At the same time, it can provide doctors with long-term clinical monitoring and physiological analysis. [Previous technology] With the advancement of biomedical technology, the blood pressure measurement for living organisms has evolved from early invasive measurement to today's non-invasive volume. Measurement. As shown in Figure 1, it is a system block diagram of a conventional non-intrusive measurement device. Mainly divided into two major categories of analog circuit 10 and digital circuit 12. The analog circuit 1 includes: a pressure sensor 1〇〇, a preamplifier 102, a high pass filter 1〇4, a low pass filter 1〇6, and a gain controller 108. The digital circuit 12 portion includes an analog/digital conversion circuit 120, a microprocessor 122, a drawing type liquid crystal display 124, a pressurizing motor, and a deflation valve 128. In a continuation, the TCM method is based on the pressure of the doctor's finger, by applying different degrees of pressure, and describing the reaction condition of the patient with his own touch, and then synthesizing all the information to assist in the diagnosis of the disease. . The most difficult place in this way is that the amount of exertion of the doctor can not be quantified and difficult to objectively record. However, in the market, the traditional pulse diagnosis apparatus H is mostly performed with a single point of J (10) single-iliac artery. Measurement, the measurement of the operation of the field fee k effort 'so' the invention to use the traditional (: continued convenience 'take the design of the just inflated, and; pulse diagnostic instrument' can provide physicians to monitor clinically Continuous pulse 1253923 way 0 [Invention content] ^The purpose of the invention 'mainly development' - the amount of different connection, and the number of miscellaneous pressure signals ^ ([power heart, use floating lift, Zhong Lin A,〗 Σσ精 is used to simulate the functional function of the Chinese medicine practitioners in the pulse to provide relevant TCM diagnosis and cardiovascular biologic auxiliary clinical application. The pressure of i II: The present invention provides - Pressing the pressure of the pulse to make a pressure pulse bag jl even 'money, its characteristics can be long-term L-determined pressure control method is easy to drink and measure - the pulse pressure signal of the limbs of the subject. The implementation of the square program The main body of the program can be divided into automatic and test, and the test mode is issued. The automatic mode adopts 10 constant constant pressure and constant pressure ^ /, the purpose is to quickly record the pulse pressure signal of the test subject. The manual mode can be used, and the user can adjust the applied pressure value as the measurement method. The purpose is to measure the continuous pulse wave signal for the systolic pressure, the average pressure and the diastolic pressure of the tester for a long time, and record the storage and analysis. - To familiarize the person skilled in the art with the purpose and characteristics of the present invention. The present invention will be described in detail by the following specific embodiments and with the accompanying drawings: w [Embodiment] FIG. 2 is a specific structural diagram of the pulse pressure signal measuring system of the present invention. The main part is composed of a cuff 20, a host circuit 22, a display device 24, and a storage device 26. The display device 24 usually adopts a drawing type liquid crystal display for displaying an instant pulse pressure signal, a differential signal, and an integral signal. , the heartbeat frequency, and the 1253923 parameter value, and then determine whether step 406 is to maintain the set time at the initial pressure value (Th), the time set by the local embodiment is 5 seconds, if If not (False), return to step 404; if the result of the determination is YES, then proceed to decision step 408 to determine whether the initial pressure value (Th) reaches a maximum pressure value (Pmax), the maximum pressure value (Pmax) The preset value in this embodiment is 120 mmHg. If not (False), the process proceeds to step 410 to activate the force port pressure motor 30, and the pressure set value (Po) is increased by a value added pressure value (Pup) to stop operation ( The value of the value-added pressure (Pup) is set to be 10 mmHg in the present embodiment, and returns to step 400. If the result of the determination is YES, the process proceeds to step 409, and the vent valve 36 is opened to the plenum bag 20 Perform rapid depressurization until OmmHg; the above steps are all in the automatic mode of the method of the present invention, as shown in Fig. 4A, the purpose of which is to measure the pulse pressure change of the subject under different pressures of pressure' as manual Reference indicator for mode measurement. Thereafter, the metrology system of the present invention will enter the manual mode as shown in Figure 4B. Step 412 applies a constant pressure value (Ps) to the inside of the cuff 20 by the pressurizing motor 30; step 414 determines whether the constant pressure value (Ps) is lower than a lower pressure limit (Pslow), if If it is (True), the process proceeds to step 416, the pressurizing motor 30 is started to pressurize the pressure bag 20, and after the pressurization, the pressurizing motor 30 is stopped, and then the process proceeds to step 414. If not (False), the process proceeds directly. Step 418; Step 418 is to determine whether the constant pressure value (Ps) is higher than a pressure upper limit value (Pshigh). If YES, then proceed to step 420 to open the deflation valve 36 to perform the pressure plenum bag 20. After stepping down, after stepping down to step 418, if not (False), step 422 is directly performed; step 422 is to measure the pulse pressure signal of the subject by the pressure sensor 200 to calculate the pulse pressure signal. The differential signal and the integral signal; the final step 424 is to set whether the constant pressure value (Ps) needs to be reset, and if so, it can be returned to step 412 to measure again. If not, the next step can be ended. 1253923 According to the manual mode of the present invention, the fewer steps 414 and 418 can achieve the effect of controlling the inflation pressure of the cuff 20 to maintain a constant pressure for a continuous period of time, wherein the lower pressure limit of step 414 is slightly less than the constant pressure (Ps). The pressure upper limit value of step 418 is slightly larger than the constant pressure value (Ps), and the constant pressure value (Ps) can be manually set, and the pressure setting range is 5 to 180 mmHg. Thereafter, after the operation of step 422, the corresponding physiological parameter values are finally calculated. It is summarized that the features of the present invention are as follows: • The method of the present invention is very easy to implement in the manner of writing firmware, and the main body of the program is divided into two modes: automatic and manual, and the automatic mode is measured and recorded by automatic control; manual The user can set the pressure of his pressure to monitor and record for a long time according to the user's own pressure. • The invention can be combined with, for example, a Compact Flash Card (Flash Card) or Smart Media

Card (SM記憶卡）此類擴充性強大的儲存媒介，因此可以儲 存長時間連續量測的大量脈壓訊號資料。 •本發明可以透過標準化電腦傳輸介面，將所擷取之脈壓訊號 資料傳輸至遠端使用之電腦進行後續的分析和處理。 雖然本發明已以一較佳實施例揭露如上，然其並非用以限 定本發明’任何熟悉此技藝者，在我離本發明之精神和範圍 内’當可作各種之更動與潤飾，因此本發明之保護 見 附之申請專利範圍所界定者為準。 田 【圖式簡單說明】 第1圖係傳統非侵入式量測裝置的系統方塊圖； 第2圖係本發明之脈壓訊號量測系統的具體架構圖； 1253923 第3圖顯示第二圖之脈壓訊號量測系統的内部方塊圖； 第4A圖係本發明之脈壓連續量測方法於自動模式時的流程圖 一； 第4B圖係本發明之脈壓連續量測方法於手動模式時的流程圖 —一-〇 【主要元件符號說明】 10 類比電路 100 壓力感測器 102 前置放大器 104 高通濾波器 106 低通濾波器 108 增益控制器 12 數位電路 120 類比/數位轉換電路 122 微處理器 124 繪圖型液晶顯示器 20 壓脈袋 200 壓力感測器 202 前置放大器 204 高通濾波器 206 低通濾波器 1253923 步驟418 步驟420 步驟422 步驟424 是否高於一壓力上限值 開啟洩氣閥 量測出受測者之脈壓訊號 是否需重新設定恆定壓力值 12Card (SM Memory Card) This powerful and powerful storage medium can store a large amount of pulse pressure signal data continuously measured for a long time. • The present invention can transmit the acquired pulse pressure signal data to a remotely used computer for subsequent analysis and processing through a standardized computer transmission interface. Although the present invention has been described above in terms of a preferred embodiment, it is not intended to limit the invention, and it is to be understood by those skilled in the art. The protection of the invention is defined by the scope of the patent application. Field [Simple diagram of the diagram] Figure 1 is a system block diagram of a conventional non-intrusive measurement device; Figure 2 is a specific architecture diagram of the pulse pressure signal measurement system of the present invention; 1253923 Figure 3 shows the second diagram The internal block diagram of the pulse pressure signal measuring system; FIG. 4A is a flow chart 1 of the pulse pressure continuous measuring method of the present invention in the automatic mode; FIG. 4B is the pulse pressure continuous measuring method of the present invention in the manual mode Flowchart—一—〇 [Main component symbol description] 10 analog circuit 100 pressure sensor 102 preamplifier 104 high pass filter 106 low pass filter 108 gain controller 12 digital circuit 120 analog/digital conversion circuit 122 micro processing 124 Photographic Liquid Crystal Display 20 Cylinder Bag 200 Pressure Sensor 202 Preamplifier 204 High Pass Filter 206 Low Pass Filter 1253923 Step 418 Step 420 Step 422 Step 424 Whether to exceed the upper limit of the pressure to open the valve Whether the pulse signal of the subject needs to be reset to a constant pressure value of 12

Claims (1)

1253923 十、申請專利範圍： 1. 一種用於四肢恆壓施壓之脈壓連續量測方法，其特徵係能 長時間以恆定之壓力控制一壓脈袋且連續量測一受測者之 四肢脈壓訊號，該方法包含下列步驟： (a) 藉由一加壓馬達對該壓脈袋内施加一初始壓力值（Th); (b) 判別該初始壓力值（Th)是否超出設定之一壓力設定值 (Po)，如果判另》J結果為是（True)，貝^關閉加壓馬達以使 壓脈袋保持恆定在該初始壓力值（Th)—段所設定之時間； (c) 由該壓力感測器量測出該受測者之脈壓訊號，且計算出該 脈壓訊號之生理參數值； (d) 判別是否在該初始壓力值（Th)下為維持所設定之時間， 如果為是(True)則直接進行下一步驟； (e) 判別該初始壓力值（Th)是否超出設定之一最大壓力值 (Pmax)，如果為是（True)，則開啟該洩氣閥以對該壓脈 袋進行降壓，並進行下一步驟； (f) 藉由該加壓馬達對該壓脈袋内施加至一恆定壓力值（Ps); (g) 判別該恆定壓力值（Ps )是否低於一壓力下限值（Pslow )， 如果為否（False)，則直接進行下一步驟； (h) 判別該恆定壓力值（Ps )是否高於該壓力上限值 (Pshigh)，如果為否（False)，則直接進行下一步驟； (i) 由該壓力感測器量測出該受測者之脈壓訊號，並計算出該 脈壓訊號之生理參數值； (j) 是否需重新設定該恆定壓力值（Ps)，如果為否（False)，則 結束步驟。 13 1253923 2.如申請專利 續量測方法 步驟(a)。 範圍第1項所述之用於四肢恆壓施壓之脈壓連 ，其中於步驟(b)中如果為否（False)，則回到 綠月專利範圍第1項所述之用於四肢恒壓施壓之脈壓連 =里測方法’其中於步驟⑷中如果為否（)，則回到 步驟(c)。 病::月專利範圍第^員所述之用於四肢恒壓施壓之脈壓連· 、’！測方法，其中於步驟(e)中如果為否（False)，則增加一 增值壓力值（Pup)，並回至步驟(a)。 ^ 5·=請專職圍第i項所述之用於四肢恒壓施壓之脈壓連 績量測方法，其中於步驟(g)中如果為是（Tme)，則啟動該 加壓馬達以對該壓脈袋進行加壓。 如申π專利範圍第1項所述之用於四肢悝壓施壓之脈壓連 續量測方法，其中於步驟(h)中如果為是（Tme)，則開啟該 洩氣閥以對該壓脈袋進行降壓。 7·如申明專利範圍第1項所述之用於四肢恆壓施壓之脈壓連 續量測方法，其中於步驟ω中如果為是（True)，則重新回 # 到步驟(f)。 8· —種用於四肢恆壓施壓之脈壓連續量測系統，其能夠以恆 定之壓力控制一壓脈袋，且長時間連續量測一受測者之動 脈壓訊號，該脈壓連續量測系統主要由該壓脈袋、一壓力 感測器、一前置放大器、一高通濾波器、一低通濾波器、 一增益控制器、一加壓馬達、一洩氣閥、一類比數位轉換 電路、一顯示裝置所組成，其主要特徵在於： 該血壓連續量測系統進一步包含一儲存裝置，其中該儲存裝 14 1253923 置連接於該微處理器，用以儲存經該微處理器處理之資 料； 該微處理器進一步包含一雙向串列通訊埤，以使經該微處 理器處理之資料可藉由該雙向串列通訊埠傳輸至一個人 電腦(pc); 該微處理器至少包括一個脈壓連續量測的程式碼，分為自 · 動與手動兩模式，在自動模式係以自動控制方式完成量 _ 測並紀錄之；手動方面可依照使用者自行設定其施壓之壓 力以進行長時間監測及紀錄，其中該程式碼能夠被該微處 籲 理器執行後，執行下列的步驟： (1) 藉由該加壓馬達對該壓脈袋内施加一初始壓力值（Th); (2) 判別該初始壓力值（Th)是否超出設定之一壓力設定值 (Po)，如果判別結果為是（True)，貝ij關閉加壓馬達以對 壓脈袋保持恆定在該初始壓力值（Th)—段所設定之時間； (3) 由該壓力感測器量測出該受測者之脈壓訊號，且計算出 該脈壓訊號之生理參數值； (4) 判別是否在該初始壓力值（Th)下為維持所設定之時間，* 如果為是(True)則直接進行下一步驟； (5) 判別該初始壓力值（Th)是否超出設定之一最大壓力值，. 如果為是（True)，則開啟該洩氣閥以對該壓脈袋進行降 壓，並進行下一步驟； ‘ (6) 藉由該加壓馬達對該壓脈袋内施加至一恆定壓力值 (Ps)； (7) 判別該恆定壓力值（Ps)是否低於一壓力下限值（Pslow)， 15 1253923 如果為否（False)，則直接進行下一步驟； (8) 判別該恆定壓力值（Ps )是否高於一壓力上限值 (Pshigh)，如果為否（False)，則直接進行下一步驟； (9) 由該壓力感測器量測出該受測者之脈壓訊號，並計算出 該脈壓訊號之生理參數值。 (10) 是否需重新設定該恒定壓力值（Ps)，如果為否（False)， 則結束步驟。 9. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中該雙向串列通訊埠係一 RS-232介面。 10. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中該儲存裝置係一可擴充之記憶卡，該記 憶卡係可為下列任一規格：Compact Flash規格、Smart Media規格。 11. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中該顯示裝置係一液晶顯示器。 12. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中於步驟(2)中如果為否（False)，則回到 步驟（1)。 13. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中於步驟(4)中如果為否（False)，則回到 步驟(3)。 14. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中於步驟（5)中如果為否（False)，則增加 一增值壓力值（Pup)，並回至步驟（1)。 16 1253923 15. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中於步驟(7)中如果為是（True)，則啟動該 加壓馬達以對該壓脈袋進行加壓。 16. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中於步驟(8)中如果為是（True)，則開啟該 洩氣閥以對該壓脈袋進行降壓。 17. 如申請專利範圍第8項所述之用於四肢恆壓施壓之脈壓連 續量測系統，其中於步驟（10)中如果為是（True)，則重新 回到步驟(6)。1253923 X. Patent application scope: 1. A continuous pulse pressure measurement method for constant pressure application of limbs. It is characterized in that it can control a pressure pulse bag with constant pressure for a long time and continuously measure the limbs of a subject. Pulse pressure signal, the method comprises the following steps: (a) applying an initial pressure value (Th) to the pressure pulse bag by a pressurizing motor; (b) determining whether the initial pressure value (Th) exceeds one of the settings Pressure setting value (Po), if the result of the judgment is J (True), the pressure motor is closed to keep the pressure pulse bag constant at the initial pressure value (Th) - the time set by the segment; (c) The pressure sensor of the subject is measured by the pressure sensor, and the physiological parameter value of the pulse pressure signal is calculated; (d) determining whether the set time is maintained under the initial pressure value (Th) If it is True, proceed to the next step; (e) Determine whether the initial pressure value (Th) exceeds one of the set maximum pressure values (Pmax), and if it is (True), open the gas release valve to Depressurizing the cuff and proceeding to the next step; (f) by the pressurization Applying a constant pressure value (Ps) to the pressure vessel; (g) determining whether the constant pressure value (Ps) is lower than a lower pressure limit (Pslow), and if not (False), proceeding directly The next step; (h) determining whether the constant pressure value (Ps) is higher than the upper pressure limit value (Pshigh), and if not (False), proceeding directly to the next step; (i) by the pressure sensor The pulse pressure signal of the subject is measured, and the physiological parameter value of the pulse pressure signal is calculated; (j) whether the constant pressure value (Ps) needs to be reset, and if not (False), the step ends. 13 1253923 2. If you apply for a patent, continue to measure method step (a). The pulse pressure connection for constant limb pressure application of the limbs according to the first item of the range, wherein if it is no (False) in the step (b), it is returned to the limbs constant according to the first item of the green moon patent range. The pulse pressure connection of the pressure application = the method of the measurement method, wherein if it is no () in the step (4), the process returns to the step (c). Disease:: The pulse pressure connection for the constant pressure of the extremities described in the second part of the patent scope of the month. The method of measurement, wherein if it is False in step (e), a value-added pressure value (Pup) is added and the process returns to step (a). ^ 5·=Please refer to the pulse pressure continuous measurement method for constant limb pressure applied in the fourth limb described in item i, wherein if it is (Tme) in step (g), the pressure motor is started. The cuff is pressurized. The method for continuously measuring pulse pressure for quadruple pressure application according to Item 1 of the scope of claim π, wherein if it is (Tme) in step (h), the vent valve is opened to the pressure pulse The bag is depressurized. 7. The pulse pressure continuous measurement method for constant limb pressure applied to the extremities according to the first aspect of the invention, wherein if Tr is in step ω, then return to step (f). 8. A pulse pressure continuous measuring system for constant pressure application of limbs, which can control a pressure pulse pocket with a constant pressure, and continuously measure the arterial pressure signal of a subject for a long time, the pulse pressure is continuous The measuring system mainly comprises the pressure pulse bag, a pressure sensor, a preamplifier, a high pass filter, a low pass filter, a gain controller, a pressurizing motor, a bleed valve, an analog to digital conversion The circuit and a display device are mainly characterized in that: the blood pressure continuous measurement system further comprises a storage device, wherein the storage device 14 1253923 is connected to the microprocessor for storing data processed by the microprocessor The microprocessor further includes a bidirectional serial communication port for transmitting data processed by the microprocessor to the personal computer (pc) by the two-way serial communication; the microprocessor includes at least one pulse pressure The continuous measurement code is divided into two modes: automatic and manual. In the automatic mode, the quantity is measured and recorded by automatic control. Manually, it can be set according to the user. The pressure of the pressure is monitored and recorded for a long time. After the code can be executed by the micro-caller, the following steps are performed: (1) An initial pressure is applied to the cuff by the pressurizing motor. Value (Th); (2) Determine whether the initial pressure value (Th) exceeds one of the set pressure set values (Po). If the result of the determination is YES, the ij closes the pressurizing motor to keep the pressure pocket constant. At the initial pressure value (Th) - the time set by the segment; (3) measuring the pulse pressure signal of the subject by the pressure sensor, and calculating the physiological parameter value of the pulse pressure signal; ) Determine whether to maintain the set time under the initial pressure value (Th), * If it is (True), proceed directly to the next step; (5) Determine whether the initial pressure value (Th) exceeds one of the set maximum Pressure value, if it is (True), the gas pressure valve is opened to depressurize the pressure pulse bag, and the next step is performed; ' (6) is applied to the pressure pulse bag by the pressure motor a constant pressure value (Ps); (7) determining whether the constant pressure value (Ps) is lower than a pressure Lower limit value (Pslow), 15 1253923 If No (False), proceed directly to the next step; (8) Determine whether the constant pressure value (Ps) is higher than a pressure upper limit value (Pshigh), if no ( False), the next step is directly performed; (9) The pressure sensor of the subject is measured by the pressure sensor, and the physiological parameter value of the pulse pressure signal is calculated. (10) Whether to reset the constant pressure value (Ps), if not (False), end the step. 9. The pulse pressure continuous measurement system for constant limb pressure application of a limb according to claim 8, wherein the two-way serial communication system is an RS-232 interface. 10. The pulse pressure continuous measuring system for constant limb pressure application of the limbs according to claim 8, wherein the storage device is an expandable memory card, and the memory card can be any of the following specifications: Compact Flash specification, Smart Media specification. 11. The pulse pressure continuous measurement system for constant limb pressure application of a limb according to claim 8, wherein the display device is a liquid crystal display. 12. The pulse pressure continuous measurement system for constant limb pressure application of the limbs according to claim 8, wherein in the step (2), if it is no (False), the process returns to the step (1). 13. The pulse pressure continuous measurement system for constant limb pressure application of the extremity as described in claim 8, wherein in the step (4), if it is no (False), the process returns to the step (3). 14. The pulse pressure continuous measurement system for constant limb pressure application of the limbs according to item 8 of the patent application, wherein in the step (5), if it is no (False), a value-added pressure value (Pup) is added. And go back to step (1). 16 1253923 15. The pulse pressure continuous measuring system for constant limb pressure application of a limb according to claim 8, wherein if the step (7) is YES, the pressure motor is activated. The cuff is pressurized. 16. The pulse pressure continuous measurement system for constant limb pressure application of a limb according to claim 8, wherein if it is true in the step (8), the gas release valve is opened to the pressure. The pulse bag is depressurized. 17. The pulse pressure continuous measurement system for constant limb pressure application of a limb according to claim 8, wherein if YES in the step (10), the process returns to the step (6). 1717
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CN105249941B (en) * 2015-11-23 2018-02-06 北京航空航天大学 A kind of pulse signal acquisition device and method of imitative pulse wave spectrum gimmick
CN206434315U (en) * 2016-11-19 2017-08-25 深圳市前海康启源科技有限公司 The special pulse detecting device of the traditional Chinese medical science
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