經濟部智慧財產局員工消費合作社印製 1236872 A7 ___B7 _ 五、發明說明（4 ) 定氮菌類（Azetobacter)、根菌類（Rhizobia)或偶氮類（azolla) 等。然而，其較好爲選擇性之除草劑、殺昆蟲劑、殺眞菌 劑、殺線蟲劑、殺藻劑、殺軟體動物劑、殺齧齒動物劑、 殺病毒劑、對植物導入抗性之化合物、生物控制劑如病 毒、細菌、線蟲、眞菌及其他微生物控制劑、鳥類及動物 排斥劑、及植物生長調節劑或數種該等製劑之混合物。 較好爲室溫下爲固體之化學農作物保護化合物，尤其是 溶點南於50 C者。 不同生物活性化合物之混合物比單一化合物具有更廣之 活性譜。再者，與單一活性成分相較，該等可展現相乘效 果。較佳具體例中，本發明之調配物可以活性成分之混合 物使用。混合物之例中，所有活性成分⑷溶於本發明SO 調配物之溶劑混合物中。 用於本發明組合物之較佳殺眞菌劑爲選自下列之市售化 合物： AC 382042 、苯胺呼（anilazine)、峻氧脱濱（azoxystrobin) 、苯拉酿（benalaxyl)、苯# 米（benomyl)、百瑞克（binapacryl) 、比特醇（bitertanol)、保米黴素（blasticidin S)、溴康峻 (bromuconazole)、布瑞莫（bupirimate)、四氯丹（captafol)、培 丹（captan)、貝芬替（carbendazim)、卡波辛（carboxin)、卡普 帕麥（carpropamid)、氯苯賽椋（chlorbenzthiazon)、氯托寧 (chlorothalonil)、氣峻林特（chlozolinate)、環己酸胺 (cycloheximide)、希莫寧（cymoxanil)、西普氟蘭（cypofuram) 、西普康峻（cyproconazole)、西普寧（cyprodinil)、大氯氟奈 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） ------------------—訂---------線 (請先閱讀背面之注意事項再填寫本頁) 1236872 A7 B7 五、發明說明（5 ) (dichlofluanid)、大氯酉同（dichlone)、大氯蘭（dichloran)、二氯 丁吨（diclobutrazol)、大羅西麥（diclocymet)、大羅美 口井 (diclomezine)、大托芬卡（diethofencarb)、大芬康峻 (difenoconazole)、大氯^ 美另（diflumetorim)、大美利莫 (dimethirimol)、大美莫氟（dimethomorph)、大利康峻 (diniconazole)、地諾卡（dinocap)、地塔利莫（ditalimfos)、二 硫隆（dithianon)、多地莫（dodemorph)、多地（dodine)、依第 芬氟（edifenphos)、環氧康峻（epoxiconazole)、依他康峻 (etaconazole)、依利莫（ethirimol)、依催二峻（etridiazole)、發 莫酮（famoxadone)、芬納寧（fenapanil)、芬納酮（fenamidone) 、非利莫（fenarimol)、芬布康吐（fenbuconazole)、芬氟蘭 (fenfuram)、芬己麥（fenhexamid)、芬皮羅寧（fenpiclonil)、芬 普比淀（fenpropidin)、芬普比莫（fenpropimorph)、芬 ί丁（fentin) 、芬；丁 乙酸鹽（fentin acetate)、菲力棕（ferimzone)、氟 口井喃 (fluazinam)、氟地氧寧（fludioxonil)、氟美托瓦（flumetover)、 氟奎康咬（fluquinconazole)、伏希峻（flusilazole)、氟舒發麥 (flusulfamide)、氟托寧（flutolanil)、氟他發（flutriafol)、發沛 (folpet)、氟波塔峻（fuberidazole)、氟拉酸（furalaxyl)、發美 比（furametpyr)、胍淀（guazatine)、己康峻（hexaconazole)、 IKF-919、依馬力（imazalil)、米諾新淀（iminoctadine)、依康 峻（ipconazole)、依普二酮（iprodione)、異丙硫蘭 (isoprothiolane)、依普瓦卡（iprovalicarb)、卡蘇黴素 (kasugamycin)、KH-7281 、替 口井 P(kitazin P)、卡嗓辛甲基 (kresoxim-methyl)、美潘琳（mepanipyrim)、美普寧（mepronil) 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁) % --線· 經濟部智慧財產局員工消費合作社印製 1236872 A7 B7 經濟部智慧財產局員工消費合作社印製 五、發明說明（6 ) 、美他酿（metalaxyl)、美康吐（metconazole)、美 蘭 (methfuroxam)、MON 65500 、美羅丁寧（myclobutanil)、新 峻辛（neoasozin)、二甲基二硫代胺基甲酸醋（nickel dimethyldithiocarbamate)、硝賽異丙基（nitrothalisopropyl)、努 力莫（nuarimol)、歐氟卡（ofurace)、有機汞化合物（organo mercury compounds)、堊大醯（oxadixyl)、氧卡辛（oxycarboxin) 、戊康峻（penconazole)、潘醯隆（pencycuron)、芬 p井氧 (phenazineoxide)、驢替汰胺（phthalide)、保利益淨（polyoxin D)、保利農（polyram)、普苯峻（probenazole)、普拉克 (prochloraz)、普醯麥酮（procymidione)、普潘卡（propamocarb) 、丙康吐（propiconazole)、甲基鋅乃浦（propineb)、比峻氣 (pyrazophos)、比芬諾（pyrifenox)、比利美寧（pyrimethanil)、 比奎隆（pyroquilon)、丙氧氟（pyroxyfur)、奎美硫奈 (quinomethionate)、奎氧芬（quinoxyfen)、奎托井（quintozene) 、羅堊胺（spiroxamine)、SSF-126 、 SSF-129 、鏈黴素 (streptomycin)、帖布康峻（tebuconazote)、估羅塔蘭 (tecloftalame)、貝占納井（tecnazene)、四康峻（tetraconazole)、 賽苯峻（thiabendazole)、賽氟醯胺（thifluzamide)、甲基多保 淨（thiophanate-methyl)、益穗（thiram)、技羅芬甲基 (tolclofosmethyl)、托利芬奈（tolylfluanid)、三泰芬 (triadimefon)、三泰蒙諾（triadimenol)、三叮替（triazbutil)、 三峻氧（triazoxide)、三環峻（tricyclazole)、三代莫（tridemorph) 、三 ll 醯托濱（trifloxystrobin)、催喊峻（triflumizole)、賽福 寧（triforine)、三替康峻（triticonazole)、維達黴素（validamycin -9 - 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） ------------------^---訂---------. (請先閱讀背面之注意事項再填寫本頁) 1236872 A7 B7 五、發明說明（7 ) A)、免克寧（vinclozolin)、XRD-563、茶利米（zarilamid)。 此外，本發明之調配物可含有下列生物控制劑之至少一 種化合物如適用於病毒、細菌、線蟲、眞菌之生物控制 劑、適用於控制昆蟲、雜草或植物疾病之其他微生物劑或 於植物中導入宿主抗性之藥劑。此生物控制劑實例包含： 蘇雲金芽胞桿菌（Bacillus thuringiensis)、乳蒜輪黴菌 (Verticillium lecanii)、宿苜銀紋夜蛾（Autographica californica NPV)、白僵菌（Beauvaria bassiana)、 Ampelomyces quisquali^ 、枯草样菌（Bacilis subtilis)、螢光假單胞菌（Pseudomonas fluorescens)、淺灰綠鏈黴菌（Steptomyces griseoviridis)及木霉 (Trichoderma harzianum) o 再者，本發明之調配物可含有至少一種可對植物謗發系 統性後天抗性之化學劑，如異菸鹼酸或其衍生物、2,2-二 氯-3,3-二甲基環丙基甲酸或BION。 該SO調配物較好包含岭幷喊症之衍生物（其揭示於歐洲 專利申請號EP 0 550 113或國際專利申請號W0 98/46608) ，尤其是下式I化合物： # (請先閱讀背面之注意事項再填寫本頁) — — — — — — 線- 經濟部智慧財產局員工消費合作社印製Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 1236872 A7 ___B7 _ V. Description of the invention (4) Aztobacter, Rhizobia or azolla etc. However, it is preferably selective herbicides, insecticides, fungicides, nematicides, algicides, molluscicides, rodenticides, virusicides, compounds that introduce resistance to plants Biological control agents such as viruses, bacteria, nematodes, pinworms and other microbial control agents, bird and animal repellents, and plant growth regulators or mixtures of several of these agents. Chemical crop protection compounds that are solid at room temperature are preferred, especially those having a melting point below 50 C. A mixture of different biologically active compounds has a broader spectrum of activity than a single compound. Furthermore, these can exhibit synergistic effects compared to a single active ingredient. In a preferred embodiment, the formulation of the present invention can be used as a mixture of active ingredients. In the case of mixtures, all active ingredients rhenium are dissolved in the solvent mixture of the SO formulation of the invention. The preferred fungicide used in the composition of the present invention is a commercially available compound selected from the group consisting of AC 382042, anilazine, azoxystrobin, benalaxyl, benzene # rice ( benomyl), binapacryl, bitertanol, blasticidin S, bromuconazole, bupirimate, captafol, captan ), Carbendazim, carboxin, carpropamid, chlorbenzthiazon, chlorothalonil, chlozolinate, cyclohexanoic acid Cycloheximide, cymoxanil, cypofuram, cyproconazole, cyprodinil, and cloflunafil This paper is sized to the Chinese National Standard (CNS) A4 (210 X 297 mm) ------------------- order --------- line (please read the precautions on the back before filling this page) 1236872 A7 B7 V. Description of the invention (5) (dichlofluanid), dichlone, dichloran, dichlorobutane (Diclobutrazol), diclocymet, diclomezine, diethofencarb, difenoconazole, diflumetorim, dimerimo (dimethirimol), dimethomorph, diniconazole, dinocap, ditalimfos, dithianon, dodemorph, multi-dihydro (Dodine), edifenphos, epoxiconazole, etaconazole, ethirimol, etridiazole, famoxadone, fen Fenapanil, fenamidone, fenarimol, fenbuconazole, fenfuram, fenhexamid, fenpiclonil, Fenpropidin, fenpropimorph, fentin, fen; fentin acetate, ferimzone, fluazinam, fludi Fludioxonil, flumetover, fluquinox Fluquinconazole, flusilazole, flusulfamide, flutolanil, flutriafol, folpet, fuberidazole, fluorine Furalaxyl, furametpyr, guazatine, hexaconazole, IKF-919, imazalil, iminoctadine, ipconazole , Iprodione, isoprothiolane, iprovalicarb, kasugamycin, KH-7281, kitazin P, carbazoxin methyl ( kresoxim-methyl), mepanipyrim, mepronil This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) (Please read the precautions on the back before filling out this page)% --Line · Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 1236872 A7 B7 Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs V. Invention Description (6), Metalaxyl, metconazole, Meilan (methfuroxam), MON 65500, beauty Myclobutanil, neoasozin, nickel dimethyldithiocarbamate, nitrothalisopropyl, nuarimol, ofurace, organic Organo mercury compounds, oxadixyl, oxycarboxin, penconazole, pencycuron, phenazineoxide, phenideine, phthalide, Polyoxin D, polyram, probenazole, prochloraz, procymidione, propamocarb, propiconazole, a Zinc is zinc (propineb), pyrazophos, pyrifenox, pyrimithanil, pyroquilon, pyroxyfur, quinomethionate ), Quinoxyfen, quintozene, spiroxamine, SSF-126, SSF-129, streptomycin, tebuconazote, rotalan (tecloftalame) Tecnazene, tetraconazole, thiabendazole, thifluzamide, thiophanate-methyl, thiram, girofin Methyl (tolclofosmethyl), tolylfluanid, triadimefon, triadimenol, triazbutil, triazoxide, tricyclazole, Trimorph, trifloxystrobin, triflumizole, triforine, triticonazole, validamycin -9-valid for this paper China National Standard (CNS) A4 Specification (210 X 297 mm) ------------------ ^ --- Order ---------. (Please Read the notes on the back before filling this page) 1236872 A7 B7 V. Description of Invention (7) A), vinclozolin, XRD-563, zarilamid. In addition, the formulations of the present invention may contain at least one of the following biological control agents such as a biological control agent suitable for viruses, bacteria, nematodes, pinworms, other microbial agents suitable for controlling insects, weeds, or plant diseases, or for plants Introduce host-resistant agents. Examples of this biological control agent include: Bacillus thuringiensis, Verticillium lecanii, Graphica californica NPV, Beauvaria bassiana, Ampelomyces quisquali ^, Subtilis Bacilis subtilis, Pseudomonas fluorescens, Steptomyces griseoviridis, and Trichoderma harzianum. Furthermore, the formulation of the present invention may contain at least one kind of Chemical agents with systemic acquired resistance, such as isonicotinic acid or its derivatives, 2,2-dichloro-3,3-dimethylcyclopropylcarboxylic acid or BION. The SO formulation preferably contains a derivative of ridge dysentery (which is disclosed in European Patent Application No. EP 0 550 113 or International Patent Application No. WO 98/46608), especially the compound of formula I below: # (Please read the back first Please note this page before filling in this page) — — — — — — Line-Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs
(R:(R:
基 烷 之 代 取 經 況 情 視 或 氮 爲 立 獨 各 2 R 中及 其 R 炔 f 基 烯 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 經濟部智慧財產局員工消費合作社印製 1236872 A7 Γ----- 五、發明說明（8) 基、烷二烯基、自烷基、芳基、雜芳基、環烷基、雙環烷 基或雜環基，或 R1與R2與鄰接氮原子一起代表視情況經取代之雜環， R3代表自原子或纟充基或烷氧基， η代表0至5之整數，及 Hal代表_原子。 較佳化合物爲式I中R1及R2與鄰接氮原子一起代表4-甲基哌啶，或其中R1代表Ck烷基尤其是異丙基、Cl_6鹵 燒基尤其是2,2,2-三氟乙基或uj·三氟丙_2_基、或c3-8 環燒基尤其是環戊基或環己基，及R2代表氫原子及/或其 中η爲2或3及R3基附接於2-、4·及6·位置且代表氟或 氯原子或Ck烷氧基。 特佳爲下列唑幷嘧啶：5-氯_6-(2-氯-6-氟苯基）-7-(4_ 甲基哌啶-1-基卜[1，2,4]三唑幷嘧啶（稱爲唑醯基嘧啶 A)、5_氯_6_(2_氣-6-氟苯基）_7·(2,2,2_三氟乙基胺基）_ [1，2,4]二唑幷[i，5-a]嘧啶（稱爲唑醯基嘧淀Β )及5•氯 (2,4,6-三氟苯基）_7_ ( 1，1，1_三氟丙_2·基胺基）三唑弁 [l，5-a]嘧啶（稱爲唑醯基嘧啶c )。 唑醯基嘧啶C由於其1Λ1•三氟丙_2•基之對掌性碳而可 以消旋混合物或富含對映異構物態施用，尤其是（8)_對映 異構物且稱爲（s)-峻gi：基喊咬c。 最佳爲至少一種式I化合物與至少一種殺眞菌活性成分 (其作爲黑色素生物合成抑制劑如AC 382042)之混合物。 較佳之除草劑爲選自下列之市售化人物： (請先閱讀背面之注意事項再填寫本頁) 訂--------線j -11- 經濟部智慧財產局員工消費合作社印製 1236872 A7 _ B7___ 五、發明說明（9 ) 2,4-D 、2,4-DB 、2,4-DP 、乙醯拉草（acetochlor)、阿西 扶芬（acifluorfen)、阿拉克羅（alachlor)、晞氧地（alloxydim)、 阿滅二酮（ametrydione)、醯胺福隆（amidosulfuron)、阿舒爛 (asulam)、阿托 p井（atrazin)、奇舒福隆（azimsulfuron)、苯扶 賽特（benfuresate)、苯舒隆（bensulfuron)、苯峻酮（bentazon) 、必芬諾（bifenox)、溴布態（bromobutide)、溴西寧 (bromoxynil)、丁拉草（butachlor)、卡芬脱（cafenstrole)、卡芬 椋（carfentrazone)、氯大椋（chloridazon)、氯姆隆（chlorimuron) 、氯普吩（chlorpropham)、氯舒隆（chlorsulfuron)、氯脱隆 (chlortoluron)、晞滅寧（cinmethylin)、晞諾舒隆（cinosulfuron) 、克羅棕（clomazone)、羅比拉（clopyralid)、氰 p井（cyanazin) 、環奈特（cycloate)、環硫醯姆隆（cyclosulfamuron)、環醯代 (cycloxydim)、大姆隆（daimuron)、去甲代芬（desmedipham)、 大滅椋（di-methazone)、大肯巴（dicamba)、大氯苯（dichlobenil) 、大氯氟（diclofop)、大幅肯（diflufenican)、大滅奈 (dimethenamid)、二硫比（dithiopyr)、硫隆（diuron)、依比坦 (eptame)、依斯卡（esprocarb)、乙硫口井（ethiozin)、芬俄普 (fenoxaprop)、芬普 _M-甲基（flamprop-M-isopropyl)、芬普-M-甲基氟 p井發（flamprop_M-methyl fluazifop)、氟滅隆 (fluometuron)、氟拉 芬（fluoroglycofen)、氟利酮（fluridone) 、氟醯批（fluroxypyr)、氟他 g同（flurtamone)、氟賽滅 (fluthiamid)、氟滅殺芬（fomesafen)、榖氟奈特 (glufosinate)、榖氟賽（glyphosate)、鹵塞芬（halosafen)、鹵酉盛 發（haloxyfop)、己 p井酮（hexazinone)、依碼滅苯 -12 · 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） ------------------—訂---------線· (請先閱讀背面之注意事項再填寫本頁) 1236872 經濟部智慧財產局員工消費合作社印製 A7 _B7_ 五、發明說明（) (imazamethabenz)、依碼滅比(imazamethapyr)、依碼莫 (imazamox)、依碼比（imazapyr)、依碼奎（imazaquin)、依碼 薩比（imazethapyr)、歐西寧（ioxynil)、異丙吐隆（isoproturon) 、異堊苯（isoxaben)、異堊氟脱（^〇叉&£1111:〇16)、乳酮芬 (lactofen)、MCPA、MCPP、美芬納（mefenacet)、偏苯硫隆 (metabenzthiazuron)、偏米隆（metamitron)、偏塔氯 (metazachlor)、甲基代姆隆（methyldimron)、美托拉草 (metolachlor)、美催布 _ (metribuzin)、美舒隆（metsulfuron)、 莫寧特（molinate)、煙驗舒隆（nicosulfuron)、奈氟椋 (norflurazon)、賽拉寧（oryzalin)、堊代吉（oxadiargyl)、堊舒 隆（oxasulfuron)、氧扶芬（oxyfluorfen)、噴代滅琳 (pendimethalin)、皮羅爛（picloram)、普利拉草（pretilachlor)、 普拉草（propachlor)、普拉寧（propanil)、普舒卡（prosulfocarb) 、吡唑舒隆（pyrazosulfuron)、p比淀特（pyridate)、奎滅克 (qinmerac)、奎拉克（quinchlorac)、奎峻氟乙基 (quizalofopethyl)、醯氧代（sethoxydim)、醯滅催（simetryne)、 舒羅三S同（sulcotrione)、舒芬三掠（sulfentrazone)、舒發賽特 (sulfosate)、帖布催（terbutryne)、帖布口井（terbutylazin)、賽滅 隆（thiameturon)、賽芬舒隆（thifensulfuron)、硫苯卡 (thiobencarb)、托氧代（tralkoxydim)、三阿來特（triallate)、三 舒隆（triasulfuron)、三苯隆（tribenuron)、催羅比（triclopyr)、 三氟琳（trifluralin) 〇 又更佳爲芳氧基皮考啉醯胺，其揭示於例如歐洲專利申 請號ΕΡ-Α-0 447 004 ，尤其是俗名爲皮考琳芬（pic〇linafen) -13- 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁) 訂---------線 1236872 A7 _B7 五、發明說明（11 ) 之N- ( 4-氣苯基）-6- ( 3-二氣甲基本乳基）p比淀-2-基甲酿 胺。 (請先閱讀背面之注意事項再填寫本頁) 殺昆蟲化合物實例爲α·赛滅寧（alpha_cypermethrin)、苯扶 卡（benfuracarb)、BPMC、佈普飛 口井（buprofezine)、卡舒芬 (carbosulfan)、培丹（cartap)、氣芬必轨（chlorfenvinphos)、甲 基陶斯松（chlorpyrifos_methyl)、環普寧（cycloprothrin)、西普 滅寧（cypermethrin)、斯芬瓦特（esfenvalerate)、乙氧芬普 (ethofenprox)、芬普帕寧（fenpropathrin)、說西寧特 (flucythrinate)、氟芬隆（flufenoxuron)、海滅隆 (hydramethylnon)、依大普（imidacloprid)、異堊隆（isoxathion) 、MEP、MPP 、奈田派忍（nitenpyram)、PAP、普滅寧 (permethrin)、普帕氟（propaphos)、才比滅 口井（pymetrozine)、稀 拉氟芬（silafluofen)、鐵布芬代（tabufenozide)、帖氟苯隆 (teflubenzuron)、田滅氟（temephos)、帖布扶（terbufos)、四氯 必芬（tetrachlorvinphos)及三峻麥（triazamate)。 通常，本發明之非水性SO調配物包括15至400克/升， 較好20至200克/升，尤其是25至100克/升之一或多種農 作物保護活性化合物。 經濟部智慧財產局員工消費合作社印製 植物油（b)較好選自橄欖油、大豆油、橘油及葵花油， 其尤其爲三酸甘油酯或三酸甘油酯之混合物包含下列脂肪 酸：棕搁酸、棕櫚油酸、硬脂酸、油酸、亞油酸、亞麻 酸。 較佳爲在25 °C具有密度小於1克/毫升，較好0.90克/ 毫升至0.95克/毫升之植物油。 -14- 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 1236872 A7 B7 經濟部智慧財產局員工消費合作社印製 五、發明說明（I2 ) 最佳爲具下列特徵之植物油 脂肪酸 撖欖油 葵花油 向油酸癸花油 棕櫚酸 12% 約1% 4% 棕櫚油酸 1% 7% 約1% 硬脂酸 3% 4% —__ 4% 油酸 75% 23% 80% 亞油酸 8% 64% 10% 亞麻酸 1% 約1% 約1% 碘値 80-88 110-143 80-95 皂化値 184-196 188-194 188-198 所示之％値爲土 3%且s 0% 通常本發明之非水性SO包括300至700克/升，較好35〇 至600克/升，尤其是4〇〇至5〇〇克/升之一或多種植物油 (b) 〇 使用作爲輔溶劑之極性非質子性溶劑（c)對增加活性成 为畺爲必要者。無該等輔溶劑，則於S〇中將溶解較少量 之活性成分且所得調配物由於增加施用至植物之溶劑量而 顯示植物毒性。較佳之極性溶劑爲在25 t顯現介電常數 2.5或更高之化合物，尤其是在25χ：之介電常數爲27至 4.0者’且具有水中低溶解度。較佳爲酮類如環己酮、内 醋如r - 丁内醋及醯胺類，尤其是環狀醯胺如N—Cws烷基 外匕洛燒嗣’較好爲烷基吡咯烷酮或n_C5 8環烷基吡 哈k嗣。最佳爲N-辛基吡咯烷酮及N-十二燒基吡咯烷 網。本發明另一較佳具體例中，輔溶劑基本上由一或多 -15- 本紙張尺賴肖+ _ ^¥F(CNS)A4規^L〇 x 297公釐) --------------------訂---------線 (請先閱讀背面之注意事項再填寫本頁) 1236872 A7 B7 經濟部智慧財產局員工消費合作社印製 五、發明說明（l3 ) 種，較好2或3種下式之二甲基二碳酸酯： H3CO-CO-(CH2)m-CO-OCH3 其中m爲2、3或4。 特佳爲由戊二酸二甲酯、丁二酸二甲酯及己二酸二甲酯 所構成之混合物，最佳爲DBE (得自Lemro Chemieprodukte Michael Mrozyk KG，Grevenbroich，德國）。 通常本發明之非水性SO包括30至200克/升，較好50至 150克/升，更好75至125克/升之一或多種極性非質子溶 劑（c)。 可使用作爲本發明之非極性水可溶混之輔溶劑（d)之甲 基化植物油爲可自中度鏈脂肪酸以甲醇酯化或以對應植物 油較妤在脂酶存在下轉酯化所得之甲酯。該等植物油之較 佳脂肪酸具有5至20個，較好6至15個碳原子。通常其 爲具有不同鏈長度脂肪酸之混合物，其中主要成分（亦即 大於該混合物之50% )具有10個碳原子之混合物特佳。較 佳具體例中，所用之甲基化植物油爲辛酸/己酸之甲酯或 具有5%以下之脂肪酸鏈長度差異爲10之己酸之甲酯。特 佳之甲基化植物油爲Witconol㊣1095及Witconol ® 2309 (其購自美國德州休士頓之Witco公司）或Edenor⑧ME C6-10 及 Edenor® ME C 12 70 (購自德國 Dusseldorf 之 Henkel KGaA)。通常本發明之非水性SO包括至少100克/升，較 好150至450克/升，尤其250至400克/升之一或多種甲基 化植物油（d)。 活性成分⑷及植物油⑻之適宜相對量，依據本發明， -16- 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） --------------------訂----I----· (請先閱讀背面之注意事項再填寫本頁) 經濟部智慧財產局員工消費合作社印製 1236872 A7 ___B7_ 五、發明說明（I5 ) 般含有1.5至40% w/v之活性成分、30至70% w/v植物 油、3至20% w/v極性非質子性溶劑、0至45% w/v甲基 化植物油、及〇至10% w/v其他添加劑如消泡劑、腐蚀抑 制劑、安定劑、滲透劑及稠化劑，及陰離子及/或非離子 分散劑。 本發明之完成之非水性SO調配物爲儲存安定，即使儲 存相當長時間亦安定。本發明之SOs可高負載有欲包含於 調配物中之一或多種殺蟲活性成分，且因此提供農作物保 護活性化合物之最適及易使用之調配物。 本發明調配物中之活性成分（a)溶解度不僅視活性成分 結構而定，亦視輔溶劑（b)之量而定。當調配物中併入10 至15%輔溶劑（c)時，活性成分（a)之相對量增加約40至 60% 〇 本發明之SO調配物較好噴霧或倒入稻田水性環境表 面，尤其是所謂之搖晃瓶應用。 調配物以單層充分擴展在水表面及黏附至稻作植物之親 脂性葉表面。 其中本發明之so調配物之固體顆粒吸附至固體載體 上，例如EP 0 415 569所述者，亦落於本發明範圍内。 本文含殺眞菌作爲活性成分之SO調配物較好對一或多 種下列疾病具有殺眞菌效果：油菜黑腐病（Xanthomonas campestris ρν· Oryzae)、稻瘟病（Pyricularia oryzae)、水稻胡 麻斑病（Cochliobolus miyabeanus)、甘蔑稍腐病（Gibberella fujikurol)、棉苗立枯病（Rhizoctonia solanz)及％ 白絹病 -18- 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） ----------------I----訂---------線· (請先閱讀背面之注意事項再填寫本頁) 1236872 A7 B7 五、發明說明（l6) (Corticium rolfsii)。本文所用之”殺眞菌效果’’意指活性成分 展現抗眞菌疾病之活性。 (請先閱讀背面之注意事項再填寫本頁) 爲了更了解本發明，特定實例敘述如下。該等實例僅用 以説明且並非用以限制本發明之範圍及理論。除了本文所 示及所述以外，本發明各種修飾將由下列實例及前述説明 變得顯而易見。此修飾係落於本發明範圍内。 本發明之非水性SO調配物示於下列實例1至4 : 實例所用之成分認證 名稱 功能 認證 Agsol Ex 8(ISP) 輔溶劑(c) N-辛基吡咯啶酮 AgsolExl2(ISP) 輔溶劑(c) N-十二烷基吡咯啶酮 橄欖油(Mosselman) 溶劑(b) ----- 三酸甘油酯，大部分爲油酸脂肪酸 高油値葵花油(Mosselman) 溶劑(b) ----- 三酸甘油酯，大部分爲油酸脂肽鹼 葵花油(Mosselman) 溶劑(b) —----- 三酸甘油酯，大部分爲亞麻酸脂肪酸 Witconol® 1095(Witco) 溶劑(d) 辛酸/己酸之技術上甲酯 Witconol® 2309(Witco) 溶劑(d) 辛酸/己酸之技術上甲酯 經濟部智慧財產局員工消費合作社印製 實例1 將活性成分溶於溶劑（b)、（c)及（d)之混合物中而製備本 發明之下列SO調配物。 -19- 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） ^236872 五、 發明說明（17 A7Substitute for alkane as the situation or nitrogen as the independent 2 R and its R alkyne f alkene The paper size applies the Chinese National Standard (CNS) A4 specification (210 X 297 mm) Employees of the Intellectual Property Bureau of the Ministry of Economic Affairs Printed by the cooperative 1236872 A7 Γ ----- V. Description of the invention (8) group, alkadienyl, self-alkyl, aryl, heteroaryl, cycloalkyl, bicycloalkyl or heterocyclic group, or R1 Together with R2 and the adjacent nitrogen atom, optionally substituted heterocycles, R3 represents self-atom or fluorenyl or alkoxy, η represents an integer from 0 to 5, and Hal represents an _ atom. Preferred compounds are those in formula I in which R1 and R2 together with adjacent nitrogen atoms represent 4-methylpiperidine, or wherein R1 represents Ck alkyl, especially isopropyl, Cl-6 haloalkyl, especially 2,2,2-trifluoro Ethyl or uj · trifluoroprop-2-yl, or c3-8 cycloalkyl, especially cyclopentyl or cyclohexyl, and R2 represents a hydrogen atom and / or wherein η is 2 or 3 and the R3 group is attached to 2 -, 4 ·, and 6 · positions and represent a fluorine or chlorine atom or a Ck alkoxy group. Particularly preferred is the following oxazolopyrimidine: 5-chloro-6- (2-chloro-6-fluorophenyl) -7- (4-methylpiperidine-1-ylbu [1,2,4] triazolopyrimidine (Referred to as oxazolyl pyrimidine A), 5-chloro-6- (2-Ga-6-fluorophenyl) _7 · (2,2,2_trifluoroethylamino) _ [1,2,4] Diazolidine [i, 5-a] pyrimidine (known as pyrazolylpyrimidine B) and 5 • chloro (2,4,6-trifluorophenyl) _7_ (1,1,1_trifluoropropion_2 · Amino group) triazolidine [l, 5-a] pyrimidine (known as oxazolyl pyrimidine c). Amidazolyl pyrimidine C can be eliminated because of its 1Λ1 • trifluoropropanyl group. Or a mixture of enantiomers, especially the (8) _enantiomer and is called (s) -jungi: the radical c is preferably at least one compound of formula I and at least one A mixture of bactericidal active ingredients (as a melanin biosynthesis inhibitor such as AC 382042). The preferred herbicide is a commercially available person selected from the following: (Please read the precautions on the back before filling this page) Order- ------ Line j -11- Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 1236872 A7 _ B7___ V. Description of Invention (9) 2,4-D, 2,4-DB, 2,4-DP, 2. acetograss chlor), acifluorfen, alachlor, alloxydim, ametrydione, amidosulfuron, asulam, atto Atrazin, azimsulfuron, benfuresate, bensulfuron, bentazon, bifenox, bromobutide, bromine (bromoxynil), butachlor, cafenstrole, carfentrazone, chloridazon, chlorimuron, chlorpropham, closulone ( chlorsulfuron), chlortoluron, cinmethylin, cinosulfuron, clomazone, clopyralid, cyanazin, cyclone ( cycloate), cyclosulfamuron, cycloxydim, daimuron, desmedipham, di-methazone, dicamba, Large chlorobenzene (dichlobenil), large chlorofluoro (diclofop), substantially diflufenican, dimethenamid, dithiopyr, diuron, eptame, esprocarb, ethiozin, fenoxaprop ), Flamprop-M-isopropyl, flamprop_M-methyl fluazifop, fluometuron, fluoroglycofen, fluorine Fluridone, fluroxypyr, flurtamone, fluthiamid, fomesafen, glufosinate, glyphosate , Halosafen, haloxyfop, hexazinone, and benzene-12 · This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) ------------------- Order --------- Line · (Please read the notes on the back before filling this page) 1236872 Intellectual Property Bureau, Ministry of Economic Affairs Printed by employee consumption cooperative A7 _B7_ V. Description of invention () (imazamethabenz), imazamethapyr, imazamox, imazapyr, imaza imazaquin), imazethapyr, ioxynil, isoproturon, isoxaben, isocalfuride (^ 〇 fork & £ 1111: 〇16), milk Lactofen, MCPA, MCPP, mefenacet, metabenzthiazuron, metamitron, metazachlor, methyldimron, metoprolin Metolachlor, metribuzin, metsulfuron, molinate, nicosulfuron, norflurazon, oryzalin, Oxadiargyl, oxasulfuron, oxyfluorfen, pendimethalin, picloram, pretilachlor, and propachlor , Propanil, prosulfocarb, pyrazosulfuron, pridate, qinmerac, quinchlorac, quinafluoroethyl ( quizalofopethyl), sethoxydim, simetryne, sulosan cotrione), sulfentrazone, sulfosate, terbutryne, terbutylazin, thiameturon, thifensulfuron, sulfur Thiobencarb, tralkoxydim, triallate, triasulfuron, tribenuron, triclopyr, trifluralin More preferred is aryloxy picolinolamine, which is disclosed in, for example, European Patent Application No. EP-A-0 447 004, especially the commonly known name picolinafen -13- This paper size applies to the country of China Standard (CNS) A4 specification (210 X 297 mm) (Please read the precautions on the back before filling this page) Order --------- line 1236872 A7 _B7 V. N- of the invention description (11) (4-Phenylphenyl) -6- (3-Difluoromethylbenzyl) p-pyridine-2-ylmethylamine. (Please read the precautions on the back before filling this page) Examples of insecticidal compounds are α · cypermethrin, benfuracarb, BPMC, bufefezine, carbosulfan ), Cartap, chlorfenvinphos, chlorpyrifos_methyl, cycloprothrin, cypermethrin, esfenvalerate, ethofenprox ), Fenpropathrin, flucythrinate, flufenoxuron, hydramethylnon, imidacloprid, isoxathion, MEP, MPP, Naita Nitenpyram, PAP, permethrin, propaphos, pymetrozine, silafluofen, tabufenozide, teflon (teflubenzuron), temephos, terbufos, tetrachlorvinphos, and triazamate. Generally, the non-aqueous SO formulations of the present invention include one or more crop protection active compounds of 15 to 400 g / L, preferably 20 to 200 g / L, especially 25 to 100 g / L. (B) is preferably selected from olive oil, soybean oil, orange oil and sunflower oil, especially triglycerides or a mixture of triglycerides containing the following fatty acids: palm oil Acids, palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid. It is preferably a vegetable oil having a density of less than 1 g / ml at 25 ° C, more preferably 0.90 g / ml to 0.95 g / ml. -14- This paper size is in accordance with China National Standard (CNS) A4 (210 X 297 mm) 1236872 A7 B7 Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 5. Description of Invention (I2) The best is vegetable oil with the following characteristics Fatty acid olive oil sunflower oil to oleic capric oil palmitic acid 12% about 1% 4% palmoleic acid 1% 7% about 1% stearic acid 3% 4% —__ 4% oleic acid 75% 23% 80% Linoleic acid 8% 64% 10% Linolenic acid 1% About 1% About 1% Iodine 値 80-88 110-143 80-95 Saponified 値 184-196 188-194 188-198 The% shown is 3 3% And s 0%. Generally, the non-aqueous SO of the present invention comprises one or more vegetable oils (b) of 300 to 700 g / L, preferably 350 to 600 g / L, especially 400 to 500 g / L. The use of a polar aprotic solvent (c) as a co-solvent is necessary to increase the activity. Without such auxiliary solvents, a smaller amount of the active ingredient will be dissolved in So and the resulting formulation will show phytotoxicity due to the increased amount of solvent applied to the plant. Preferred polar solvents are compounds which exhibit a dielectric constant of 2.5 or higher at 25 t, especially at 25x: those having a dielectric constant of 27 to 4.0 'and have low solubility in water. Ketones such as cyclohexanone, internal vinegars such as r-butyrolactone, and amidines, especially cyclic amidines such as N-Cws alkyl alkalene, preferably alkylpyrrolidone or n_C5 8 Cycloalkyl pyrha k 嗣. Most preferred are N-octylpyrrolidone and N-dodecylpyrrolidine network. In another preferred embodiment of the present invention, the co-solvent is basically composed of one or more -15- this paper rule Lai Xiao + _ ^ ¥ F (CNS) A4 gauge ^ L 〇 x 297 mm) ------ -------------- Order --------- line (Please read the precautions on the back before filling this page) 1236872 A7 B7 Printed by the Employees' Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs Preparation 5. Description of the invention (l3), preferably two or three dimethyl dicarbonates of the formula: H3CO-CO- (CH2) m-CO-OCH3 where m is 2, 3 or 4. Particularly preferred is a mixture of dimethyl glutarate, dimethyl succinate and dimethyl adipate, most preferably DBE (available from Lemro Chemieprodukte Michael Mrozyk KG, Grevenbroich, Germany). Generally, the non-aqueous SO of the present invention comprises one or more polar aprotic solvents (c) of 30 to 200 g / l, preferably 50 to 150 g / l, more preferably 75 to 125 g / l. The methylated vegetable oil that can be used as the non-polar water-miscible co-solvent (d) of the present invention is obtained by methyl esterification of a medium-chain fatty acid with methanol or transesterification with a corresponding vegetable oil in the presence of lipase Methyl ester. The preferred fatty acids of these vegetable oils have 5 to 20, preferably 6 to 15 carbon atoms. Usually it is a mixture of fatty acids with different chain lengths, with a main component (i.e. greater than 50% of the mixture) having 10 carbon atoms being particularly preferred. In a more specific example, the methylated vegetable oil used is methyl ester of octanoic acid / hexanoic acid or methyl ester of hexanoic acid having a fatty acid chain length difference of 10% or less. Particularly preferred methylated vegetable oils are Witconol (R) 1095 and Witconol (R) 2309 (purchased from Witco Corporation of Houston, Texas, USA) or Edoror (R) ME C6-10 and Edenor (R) ME C 12 70 (purchased from Henkel KGaA, Dusseldorf, Germany). Generally, the non-aqueous SO of the present invention comprises one or more methylated vegetable oils (d) of at least 100 g / l, preferably 150 to 450 g / l, especially 250 to 400 g / l. The appropriate relative amounts of active ingredient ⑷ and vegetable oil ，, according to the present invention, -16- this paper size applies to China National Standard (CNS) A4 (210 X 297 mm) ------------- ------- Order ---- I ---- · (Please read the notes on the back before filling out this page) Printed by the Employees' Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 1236872 A7 ___B7_ V. Description of Invention (I5 ) Generally contains 1.5 to 40% w / v of active ingredients, 30 to 70% w / v vegetable oil, 3 to 20% w / v polar aprotic solvent, 0 to 45% w / v methylated vegetable oil, and To 10% w / v other additives such as defoamers, corrosion inhibitors, stabilizers, penetrants and thickeners, and anionic and / or nonionic dispersants. The completed non-aqueous SO formulation of the present invention is stable in storage, even when stored for a long time. The SOs of the present invention can be highly loaded with one or more pesticidally active ingredients to be included in the formulation, and thus provide the most suitable and easy-to-use formulation of crop protection active compounds. The solubility of the active ingredient (a) in the formulation of the present invention depends not only on the structure of the active ingredient, but also on the amount of the auxiliary solvent (b). When 10 to 15% of the co-solvent (c) is incorporated in the formulation, the relative amount of the active ingredient (a) increases by about 40 to 60%. The SO formulation of the present invention is preferably sprayed or poured onto the aqueous environment surface of the rice field, especially Is the so-called shake bottle application. The formulation fully spreads in a single layer on the water surface and on the surface of the lipophilic leaves attached to the rice plant. The solid particles of the so formulation according to the present invention are adsorbed onto a solid support, such as those described in EP 0 415 569, which also fall within the scope of the present invention. The SO formulation containing bactericidal fungi as an active ingredient has better bactericidal effects on one or more of the following diseases: rape black rot (Xanthomonas campestris ρν Oryzae), rice blast (Pyricularia oryzae), rice flax spot Cochliobolus miyabeanus), Gibberella fujikurol, Rhizoctonia solanz, and% white silk disease-18- This paper is in accordance with China National Standard (CNS) A4 (210 X 297 mm) ---------------- I ---- Order --------- Line · (Please read the precautions on the back before filling this page) 1236872 A7 B7 Five Description of the invention (16) (Corticium rolfsii). As used herein, "killer fungicidal effect" means that the active ingredient exhibits the activity against the bacterium disease. (Please read the precautions on the back before filling out this page.) In order to better understand the present invention, specific examples are described below. These examples are only It is used to illustrate and not to limit the scope and theory of the present invention. In addition to what is shown and described herein, various modifications of the present invention will become apparent from the following examples and the foregoing description. This modification falls within the scope of the present invention. The non-aqueous SO formulations are shown in the following Examples 1 to 4: Ingredients used in the examples Certification name Functional certification Agsol Ex 8 (ISP) Co-solvent (c) N-octyl pyrrolidone Agsol Exl 2 (ISP) Co-solvent (c) N -Dodecyl pyrrolidone olive oil (Mosselman) solvent (b) ----- triglyceride, most of which are oleic acid fatty acid high oil sunflower oil (Mosselman) solvent (b) ----- Triglycerides, most of which are oleate lipopeptide base sunflower oil (Mosselman) Solvent (b) —----- Triglycerides, most of which are linolenic acid fatty acid Witconol® 1095 (Witco) Solvent (d) Caprylic acid / Caproic acid technical methyl ester Witconol® 2309 (Witco) Solvent (d) Caprylic acid / caproic acid Technically methyl ester printed by the Consumer Cooperative of Intellectual Property Bureau of the Ministry of Economic Affairs Example 1 Dissolve the active ingredients in a mixture of solvents (b), (c) and (d) to prepare the invention The following SO preparations. -19- This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) ^ 236872 V. Description of the invention (17 A7
配物： 濃度 _J：S)·唑幷嘧啶C 30克 ^橄欖油 450克 、Agsol Ex 8 1〇〇克 ____Witconol 1095 至1升 孩SO調配物展現下列性質： 密度：0.912克/毫升；閃點>83 °C ; 在〇 °C儲存1週後未形成結晶。 實例2 將活性成分溶於溶劑（b)、（c)及⑷之混合物中而製備本 發明之下列SO調配物。 張 紙 __一本 經濟部智慧財產局員工消費合作社印製 獲得下列調配物： ‘成分 濃度 _唑并嘧啶C 30克 — _ 南油値秦化油 400克 Agsol Ex 8 90克 Witconol 2309 至1升 實例 將活性成分溶於溶劑（b)、（c)及⑷之混合物中 發明之下列SO調配物。 而製備本 -20- L度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁)Formulations: Concentration_J: S). 30 mg of pyrazolam C, 450 g of olive oil, Agsol Ex 8 100 g____Witconol 1095 to 1 liter of child SO formulations exhibit the following properties: Density: 0.912 g / ml; Flash point > 83 ° C; No crystals formed after 1 week storage at 0 ° C. Example 2 The following SO formulations of the present invention were prepared by dissolving the active ingredient in a mixture of solvents (b), (c) and rhenium. Zhang Zhi__ A printed copy of the employee's consumer cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs has obtained the following formulations: 'Composition Concentration_Zolopyrimidine C 30g — _ Nanyou Qinhua Oil 400g Agsol Ex 8 90g Witconol 2309 to 1 Examples The following active SO compounds were invented by dissolving the active ingredient in a mixture of solvents (b), (c) and rhenium. The preparation of this -20-L degree is applicable to China National Standard (CNS) A4 specifications (210 X 297 mm) (Please read the precautions on the back before filling this page)
1236872 A7 B7 五、發明說明（I8 ) 獲得下列調配物： 成分 濃度 唑幷嘧啶C 30克 AC 382042 100克 橄欖油 400克 Agsol Ex 12 100克 Witconol 1095 至1升 (請先閱讀背面之注意事項再填寫本頁) 實例4 將活性成分溶於溶劑（b)、(c)及（d)之混合物中而製備本 發明之下列SO調配物。 獲得下列調配物： 成分 濃度 氟賽滅 30克 橄欖油 450克 Agsol Ex 8 150克 Witconol 1095 至1升 稻瘟病之防治 經濟部智慧財產局員工消費合作社印製 ’’Koshihikari”品種之水稻植物於苗圃箱中生長及移植至 457 cm2面積之溫室中（4株/盆）。移植3天後，於水中添 加（S)-嗤幷喃淀C之不同調配物。以活性成分處理45天後 植物以稻痙病孢子溶液接種。未處理區亦包含於此測試 中。 A.稻葉枯萎 處理52天後，未處理稻植物（對照組）之葉面63%以稻 -21 - 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 1236872 經濟部智慧財產局員工消費合作社印製 A7 _B7_ 五、發明說明（I9) 枯萎病感染。亦評估處理植物之疾病率（受感染葉面％)， 及測量處理效率（％)。本發明so調配物及顆粒調配物之效 果示於表I。 表I稻葉枯萎防治％ 活性成分 劑量 (克/公畝） 防治2 ^(%) SO 30克/升 (實例1) 顆粒50克/公斤 (S)-唑幷嘧啶C 50 84 未測定 100 89 78 250 95 86 500 97 90 1000 98 95 1500 未測定 97 普苯唑 2400 74 顆粒80克/公斤 B.稻圓錐枯萎 處理126天後，未處理稻植物（對照組）之葉面6 0 %以稻 枯萎病感染。亦評估處理植物之疾病率（受感染葉面％ )， 及測量處理效率（％)。本發明SO調配物及顆粒調配物之效 果示於表II。 -22- 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） --------------------訂---------線"fp (請先閱讀背面之注意事項再填寫本頁) 1236872 A7 B7 五、發明說明（) 表II稻圓錐枯萎防治％ 活性成分 劑量 (克/公故） 防治率(％) SO 30克/升 (實例1) 顆粒50克/公斤 (S)-唑幷嘧啶C 50 22 未測定 100 44 39 250 67 44 500 78 67 1000 84 82 普苯唑 2400 69 顆粒80克/公斤 該等試驗明顯證明對相同之疾病防治以本發明之SO調 -------------¾ (請先閱讀背面之注意事項再填寫本頁) 配物劑量比習知顆粒調配物降低50%。 此外，在測試應用率下植物毒性可忽略。 再者，本發明之SO調配物比習知調配物更具環境溫和 性且具有改良之毒性輪靡而使該等調配物處理更安全。 -23- 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 訂--------線· 經濟部智慧財產局員工消費合作社印製1236872 A7 B7 V. Description of the invention (I8) Obtain the following formulations: Concentration of azole pyrimidine C 30 g AC 382042 100 g olive oil 400 g Agsol Ex 12 100 g Witconol 1095 to 1 liter (please read the precautions on the back first) (Fill in this page) Example 4 The active ingredient is dissolved in a mixture of solvents (b), (c) and (d) to prepare the following SO formulations of the present invention. Obtained the following formulations: Concentration of fluoxan 30 grams of olive oil 450 grams of Agsol Ex 8 150 grams of Witconol 1095 to 1 liter of rice blast prevention and control The Ministry of Economic Affairs Intellectual Property Bureau employee consumer cooperative printed rice plants of "Koshihikari" variety in the nursery The box was grown and transplanted to a greenhouse (4 plants / pot) with an area of 457 cm2. After transplantation for 3 days, different formulations of (S) -Aran-C were added to the water. After 45 days of treatment with the active ingredients, the plants were treated with Rice spasm spore solution inoculation. Untreated area is also included in this test. A. After 52 days of rice leaf withering, 63% of the leaves of the untreated rice plant (control group) are rice-21-This paper scale applies to China Standard (CNS) A4 specification (210 X 297 mm) 1236872 Printed by the Consumers ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs A7 _B7_ V. Description of the invention (I9) Fusarium infection. The disease rate of the treated plants is also evaluated (% of infected foliage) ), And measure the treatment efficiency (%). The effects of the so formulations and granule formulations of the present invention are shown in Table I. Table I Control of rice leaf wilt% Active ingredient dosage (g / area) Control 2 ^ (%) SO 30 g / (Example 1) Granules 50 g / kg (S) -oxazolidine C 50 84 Not determined 100 89 78 250 95 86 500 97 90 1000 98 95 1500 Not determined 97 Propiconazole 2400 74 Granules 80 g / kg B. Rice After 126 days of cone wilt treatment, 60% of the leaves of the untreated rice plant (control group) were infected with rice wilt. The disease rate of the treated plants (% of infected leaf surface) was also evaluated, and the treatment efficiency (%) was measured. The effects of the SO formulations and granular formulations of the present invention are shown in Table II. -22- This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) ------------ -------- Order --------- line " fp (Please read the precautions on the back before filling this page) 1236872 A7 B7 V. Description of the invention () Table II Rice cone wilt prevention % Active ingredient dosage (g / common) Control rate (%) SO 30 g / l (Example 1) Granules 50 g / kg (S) -oxazolidine C 50 22 Not determined 100 44 39 250 67 44 500 78 67 1000 84 82 Prazole 2400 69 Granules 80 g / kg These tests clearly prove that the same disease prevention and treatment with the present invention SO-tuned ------------- ¾ (please read the back first Note then fill page) than conventional formulations were dose reduced by 50% particulate formulations. In addition, phytotoxicity is negligible at the test application rate. Furthermore, the SO formulations of the present invention are more environmentally mild and have improved toxicity than conventional formulations, making such formulations safer to handle. -23- This paper size is in accordance with Chinese National Standard (CNS) A4 (210 X 297 mm) Order -------- Line Printed by the Consumer Cooperative of Intellectual Property Bureau of the Ministry of Economic Affairs