1235672 A7 經濟部智慧財產局員工消費合作社印製 五、發明說明（I ) 發明頜域 本發明係相關於一種單次使用式注射器，尤其相關於 一種在至少某些實施例中能夠將逆流限制在一顯著範圍內 之注射器。 發明背景 如同在澳洲專利第7 0 8 4 4 5號中所討論者，吾人 係意識到一種注射器之需求，該種注射器係能夠適合於以 一種讓注射器於組完時能夠被使用，但是僅能對容置於該 注射器內的藥劑進行遞送一次之方式來遞送藥劑。更進一 步意識到的是，如同在某些形式中所描述的，該注射器係 絕不可在一個逆向上使用，不然就會容許逆流發生，亦即 液體係在一個逆向於遞送方向之方向上移動於注射器內。 澳洲專利第7 0 8 4 4 5號係揭示了一種基本組件， 其於至少某些實施例之中係可以提供此一類型之功能。澳 洲專利第7 0 8 4 4 5號的揭示內容係合倂於此作爲本案 之交互參考。 本發明之至少是較佳形式之目的係提供一種可替換或 是改良式操作及遞送模式，或者至少提供一種有用的選擇 (請先閱讀背面之注意事項為填寫本頁) -裝---- 訂--- # 發明槪要 據此，在本發明的一種廣泛的形式中，其係提供了一 種單次使用式注射器，該單次使用式注射器係包括有完備 3 ^紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐) ' "" ~ 1235672 Λ7 B7 五、發明說明（>) 之儲存機構，該儲存機構係適合於將一預定容量而包括有 一預定藥劑劑量之物質密封地保持於其中；該儲存機構係 具有位於其第一端部處的致動器機構之銜接機構；該儲存 機構係具有位於其第二端部處的遞送機構之銜接機構。 較佳地，該遞送機構之銜接機構係包括有一個易破型 密封件，該密封件係於運送期間將該液體保持在該儲存機 構之中；該易破型密封件係適合於在遞送機構被帶至與該 遞送機構之銜接機構相互銜接期間破裂開。 較佳地，該注射器更包括有遞送機構。 較佳地，該遞送機構係包括有閥體機構。 較佳地，該閥體機構係爲一種單向閥。 較佳地，該遞送機構係以一種不可脫離地附接至該完 備的儲存機構之該第二端部。 較佳地，該儲存機構係包括有一個與其成爲一體之單 向閥體機構。 較佳地，該遞送機構係包括有一個針頭組件。 較佳地，該遞送機構係包括有一個與其他遞送系統連 接之連接裝置。 較佳地，該遞送機構係包括有一個調整器套筒；該調 整器套筒係包括有非可釋放式銜接機構，用於該調整器套 筒至該完備的儲存機構之該第二端部的非可釋放式附接。 較佳地’該調整器套筒之該非可釋放式銜接機構係合 倂有一種多段式、螺旋作用式鎖定機構。 較佳地’該多段式、螺旋作用式鎖定之機構係包括有 4 本紙張尺度適用中國ΐ家標準（CNS)A4規格（210 X 297公釐）1235672 A7 Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 5. Description of the Invention (I) Invention of the Jaw Field The present invention relates to a single-use syringe, and in particular to a method capable of limiting the countercurrent to A significant range of syringes. BACKGROUND OF THE INVENTION As discussed in Australian Patent No. 7 0 445, we are aware of the need for a syringe that can be adapted to use a syringe when it is finished, but only The medicament contained in the syringe is delivered once to deliver the medicament. It is further realized that, as described in some forms, the syringe must never be used in a reverse direction, otherwise it will allow countercurrent to occur, that is, the liquid system moves in a direction opposite to the direction of delivery. Inside the syringe. Australian Patent No. 7 0 8 4 4 discloses a basic component that can provide this type of function in at least some embodiments. The disclosure of Australian Patent No. 7 0 8 4 4 is incorporated herein as a cross-reference to this case. The purpose of at least the preferred form of the present invention is to provide an alternative or improved operation and delivery mode, or at least provide a useful option (please read the notes on the back first to fill out this page) -installation ---- Order --- # invention 槪 According to this, in a broad form of the present invention, it provides a single-use syringe, the single-use syringe includes a complete 3 ^ paper size applicable Chinese national standards (CNS) A4 size (210 X 297 mm) '" " ~ 1235672 Λ7 B7 V. Storage mechanism of the invention (>), the storage mechanism is suitable for including a predetermined capacity including a predetermined pharmaceutical dose The substance is hermetically held therein; the storage mechanism is an engagement mechanism having an actuator mechanism at its first end; the storage mechanism is an engagement mechanism with a delivery mechanism at its second end. Preferably, the coupling mechanism of the delivery mechanism includes a frangible seal, the seal holds the liquid in the storage mechanism during transportation; the frangible seal is suitable for the delivery mechanism It was ruptured during being brought into engagement with the delivery mechanism. Preferably, the syringe further includes a delivery mechanism. Preferably, the delivery mechanism includes a valve body mechanism. Preferably, the valve body mechanism is a one-way valve. Preferably, the delivery mechanism is inseparably attached to the second end of the complete storage mechanism. Preferably, the storage mechanism includes a one-way valve body mechanism integrated with it. Preferably, the delivery mechanism includes a needle assembly. Preferably, the delivery mechanism includes a connecting device for connection with other delivery systems. Preferably, the delivery mechanism includes an adjuster sleeve; the adjuster sleeve includes a non-releasable coupling mechanism for the adjuster sleeve to the second end of the complete storage mechanism Non-releasable attachment. Preferably, the non-releasable engaging mechanism of the adjuster sleeve is combined with a multi-section, screw-acting locking mechanism. Preferably, the multi-segment, screw-acting locking mechanism includes 4 paper sizes applicable to the Chinese Standard (CNS) A4 (210 X 297 mm).
(請先閱讀背面之注意事S r,裝--- P寫本頁) . 經濟部智慧財產局員工消費合作社印制衣 1235672 A7 B7 經濟部智慧財產局員工消費合作社印製 五、發明說明) 與該遞送機構及該儲存機構相聯結之齒部’該齒部係被構 型以便容許該儲存機構能夠前進而與該遞送機構相銜接， 但能夠抵抗該儲存機構從該遞送機構處之分離。 較佳地，該單向閥係包括有一個球根狀容室，而在該 球根狀容室中係具有一個球體。 較佳地，該單向閥係坐落在該調整器套筒內。 較佳地，該單向閥係坐落在該遞送機構內。 較佳地，該單向閥係坐落在該儲存機構內。 較佳地，該注射器更包括有致動器機構。 較佳地，該致動器機構係包括有一個柱塞。 較佳地，該致動器機構係包括有儲存機構之銜接機構 ’用於以一種可釋放方式銜接一個位於該儲存機構中之可 移動式密封件。 較佳地，該注射器更包括有一個可移動式密封件，並 且其中，該可移動式密封件係於該儲存機構內界定有一個 儲存容積；該儲存容積之容積係會依據該可移動式密封件 於該儲存機構內的位置而改變。 較佳地，該致動器機構係包括有一個可移動式阻隔件 ’該可移動式阻隔件係作用以藉由該致動器機構來將該可 移動式密封件上的致動限制至一個預裝塡移動，藉此該柱 塞相對於該儲存機構之移動係可以被停止於一個預裝塡位 置處。 較佳地，該預裝塡之移動係藉由位在該儲存機構中之 該物質而導致注入該遞送機構。 本紙張尺度適用中國國家標準（CNS)A4規格（210 x 297公釐） (請先閱讀背面之注意事項㈣填寫本頁) i 裝 . 1235672 A7 _—___B7___ 五、發明說明（Y ) 較佳地，該預裝塡位置係相應於該預定容積內之物質 的容積係爲該藥劑的預定劑量。 較佳地，該致動器機構係以一種能夠讓該致動器機構 避免導致該可移動式密封件產生一個方向之移動的方式， 而能夠從該可移動式密封件處脫離，此將增加被界定於該 儲存機構中之容積。 在本發明的一個更廣泛的形式之中，其係提供了一種 與上述注射器一起使用的針頭組件。 在本發明的一個更廣泛的形式之中，其係提供了一種 與上述注射器一起使用的柱塞。 在本發明的一個更廣泛的形式之中，其係提供了一種 與上述注射器一起使用的單向閥。 在本發明的一個更廣泛的形式之中，其係提供了一種 與上述注射器一起使用的調整器套筒。 在本發明的一個更廣泛的形式之中，其係提供了一種 與上述注射器一起使用的成套組合部件。 圖示簡單說明 現在將敘述本發明之實施例，其中： 第一圖係爲根據本發明之第一實施例之單次使用式注 射器組件的分解之側視圖； 第二A圖至第二I圖係說明了第一圖中用於藥劑遞送 之注射器的組裝及使用的連續步驟；以及 第三A —三L圖係更進一步地說明了第一圖中用於注 6 (請先閱讀背面之注意事項^填寫本頁) 1· ·1111111 經濟部智慧財產局員工消費合作社印製 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 1235672 A7 B7 五、發明說明（<) 射之單次使用式注射器組件的組裝及使用的步驟。 圖示丰要元件符號說明 經濟部智慧財產局員工消費合作社印製 10 單次使用式注射器組件 11 圓筒造型容器 12 儲存容量 13 可移動式密封件 14 縱向軸線 15 內側壁部 16 第一端部 17 長形柱塞 18 未固定式密封連接器/突出 部或板釘插銷 19 柱塞連接器容座 2 0 後方表面 2 1 端部位置 2 2 容器出口 2 3 薄膜 2 4 第二端部 2 5 第一銜接齒部 2 6 第二銜接齒部 2 7 齒部支承單元 2 8 狹槽 2 9 接合套筒 7 (請先閱讀背面之注意事填寫本頁) 1 丨裝 訂· 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 1235672 B7 五、發明說明（L ) 3 0 3 1 3 2 3 3 3 4 3 6 3 7 3 8 3 9 4 0 4 1 4 2 4 3 4 4 4 5 4 6 4 7 4 8 4 9 5 0 5 1 5 2 5 3 5 4 第一端部/遞送端部 針頭組件 灌注連接器 第二端部/接收端部 螺旋造型通道 第一齒部阻隔件 傾斜表面 第二齒部阻隔件 長形針頭 尖端 接收端部 球根狀容室 閥球體 長形遞送通道 針頭外殼 調整器套筒銜接齒部 調整器遞送管件 遞送端部 接收端部 頂端 突出部分 可移動式阻隔件 制動位置 鉸接線 (請先閱讀背面之注意事項為填寫本頁) n —^1 —ϋ «_ϋ 一口t · ala— ϋ 11 11 1>1 11 n 經濟部智慧財產局員工消費合作社印製 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 1235672 A7 B7 五、發明說明（q ) 5 5 前引（制動）邊緣 5 6 狹槽 5 7 柱塞主體 6 0 套件 6 1 塑膠袋 經濟部智慧財產局員工消費合作社印製 去奮施例詳細說明 在說明書中，下文中的用詞「液體（liquid)」係被使 用來描述被儲存在注射器組件中，並且最後藉由注射器組 件所遞送的物質而言。應當了解的是，除了遞送液體之外 ，該注射器組件係可以被使用於遞送其他物質，例如是液 體與固體懸浮物質的混合物、液體之混合物、流體之混合 物、或是前述二者之組合。 參照第一圖，其係說明了根據本發明之第一較佳實施 例的單次使用式注射器組件1 0。 在這一個例子之中，該組件1 0係包括有儲存機構， 該儲存機構係以一種圓筒造型容器1 1的形式呈現，該圓 筒造型容器11係具有一個被界定於其中之儲存容量12 。該儲存容量12之精確容量係爲藉由一個可移動式密封 件1 3所決定者，該可移動式密封件1 3總是以一種密封 的、可滑動的方式沿著圓筒造型容器1 1之縱向軸線1 4 移動’而在移動期間係保持與圓同造型谷益1 1之內側壁 部15以一種密封方式相接觸。圓筒造型容器1 1之第一 端部1 6係適合以一種滑動方式將一個長形柱塞1 7接收 9 _本紙張尺度適用中國國家標準（CNS)A4規格（21G x 297公^ (請先閱讀背面之注意事項一^填寫本頁) 裝 一aj·. #. 1235672 A7 _ B7 五、發明說明（g) 於其中。該柱塞1 7係爲長形者，並且係適合沿其縱軸而 對準圓筒造型容器1 1之縱向軸線1 4，並且前進至圓筒 造型容器1 1之第一端部1 6中，使得位於其前引邊緣處 之未固定式密封連接器18能夠座落在位於可移動式密封 件1 3之後方表面2 0中的柱塞連接器容座19內。在這 一個例子之中，該柱塞連接器容座1 9係以一種空腔的形 式呈現，其係適合於接收以一突出部或板釘插銷形式所呈 現之未固定式密封連接器1 8。該未固定式密封連接器1 8在該柱塞連接器容座1 9內的容置係使得該柱塞1 7總 是能夠簡單地藉由使柱塞1 7之移動反向，而得以輕易地 從一種與可移動式密封件1 3之銜接狀態中脫離，以使其 能夠移離圓筒造型容器1 1之外，並且沿著縱向軸線1 4 而從第一端部1 6處離開’並且在柱塞1 7之移動方向被 反向時之位置處離開被保持在圓筒造型容器11內之可移 動式密封件1 3。 該柱塞1 7係具有充分之長度，因此其係可以被利用 來迫使可移動式密封件13—路沿著縱向軸線14而到達 圓筒造型容器1 1內之一個端部位置2 1，在如此進行之 下，其係會迫使位在儲存容量1 2中之內容物在容器出口 2 2的方向上移動。 在這樣的情況之中，圓筒造型容器1 1係包括有一個 以一薄膜2 3形式所呈現之易破型密封件，其係爲了圓筒 造型容器1 1之運送而將容器出口 2 2密封起來，從而能 夠在運送期間防止儲存容量1 2內之液體流出。 10 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐) "一~" 一 (請先閱讀背面之注意事項1^填寫本頁) —裝 訂· 經濟部智慧財產局員工消費合作社印製 1235672 A7 B7 五、發明說明（1) 圓筒造型容器1 1之第二端部2 4 (遞送端部）亦合 倂有遞送機構銜接機構，而在此例子之中，其係以第一銜 接齒部2 5以及第二銜接齒部2 6的形式呈現，該第一及 第二銜接齒部2 5及2 6二者係被裝設在大致上圓柱形的 齒部支承單元2 7上，該齒部支承單元2 7本身係從該容 器1 1之第二端部2 4處向外延伸。 參照第三C圖以及第三D圖，該齒部支承單元2 7係 包括有位於其中之相對狹槽2 8，該等狹槽2 8係具有充 分的寬度，用以容許齒部2 5及2 6能夠進行至少有限的 向內撓曲，用以幫助齒部2 5及2 6與遞送機構之相互銜 接，而此將於下文中予以描述及討論。 在這個例子之中，該遞送機構係包括有一個接合套筒 2 9，其係於其第一或遞送端部3 0處接收一個遞送裝置 ，例如是一個針頭組件3 1或是一個灌注連接器3 2 ’或 者連接至例如是藉由一種路厄氏（Liier)類型之裝置所能 夠執行之其他遞送系統。 該接合套筒2 9於其第二端部或接收端部3 3處係適 合以一種無法釋放的方式與圓筒造型容器11之遞送機構 的銜接機構相銜接，在這個例子之中，該遞送機構的銜接 機構係包括有該嚼合齒部25及26以及該容器出口22 0 該齒部2 5及2 6係銜接在一螺旋造型通道3 4中， 該螺旋造型通道3 4係坐落在套筒2 9的內側壁部之上或 之中，並且在圓筒造型容器1 1相對於該套筒2 9而被扭 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） ------------裝—— (請先閱讀背面之注意事寫本頁) . 經濟部智慧財產局員工消費合作社印製 1235672 經濟部智慧財產局員工消費合作社印製 A7 B7 五、發明說明（) 轉之時係會沿著通道而前進，直到其遭遇到第一齒部阻隔 件3 6爲止。在這樣的狀況下，該圓筒造型容器1 1與該 接合套筒2 9間之更進一步的銜接係藉由將圓筒造型容器 1 1沿著縱向軸線1 4而在套筒2 9的方向上向前推動所 達成，據此，齒部2 5及2 6係可以行進向上並越過阻隔 件3 6之傾斜表面3 7 (參照第二A圖），從而容許該齒 部2 5及2 6在通道3 4中能夠隨著容器1 1相對於套筒 2 9之連續扭轉移動而連續地行進。 在這一個實施例之中，第二齒部阻隔件3 8係從第一 齒部阻隔件3 6沿著通道3 4而被更進一步地置放，該等 阻隔件在最後及完成之則亦必須以一種相關於第一齒部阻 隔件3 6所描述的方式而被齒部2 5及2 6所越過，容器 1 1之密封以及非可釋放式銜接係經由調整器套筒2 9所 達成。 在這個例子之中，該遞送機構除了包括有套筒2 9之 外，亦包括有一個被銜接於該調整器套筒2 9之第一端部 或遞送端部3 0內的針頭組件3 1。 特別的情況是，該針頭組件3 1 (參照第一圖以及第 二A圖）係包括有長形針頭3 9，該長形針頭3 9於其一 遞送端部處係具有一個尖端4 0，而適合於幫助插入至存 活的組織之中。 在該針頭3 9的一個接收端部4 1處係爲一個球根狀 容室4 2，該球根狀容室4 2係適合於將閥球體4 3接收 於其內。該球根狀容室4 2係具有與閥球體4 3之尺寸相 12 --------------- (請先閱讀背面之注意事填寫本頁) 訂： 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 1235672 經濟部智慧財產局員工消費合作社印製 Λ7 B7 五、發明說明（u ) 較之下更爲充分的容積，並且係以一種讓該閥球體4 3無 法妨礙液體在針頭3 9內之長形遞送通道4 4的方向上向 前行進而通過容室4 2的方式來加以配置。 針頭外殻4 5係抓住針頭3 9的接收端部4 1，並且 係包括有調整器套筒銜接齒部4 6，隨著針頭組件3 1之 該接收端部4 1插入至調整器套筒2 9之該遞送端部之中 ，調整器套筒銜接齒部4 6係以一種機械方式銜接該調整 器套筒2 9，以使得該針頭組件3 1之接收端部4 1能夠 以一種讓包括有球根狀容室4 2之遞送通道4 4被置放成 與調整器遞送管件4 7之遞送端部以流體相連通的方式， 而被保持在該調整器套筒2 9之中，該調整器遞送管件4 7係被容置在該調整器套筒2 9之中並且形成該調整器套 筒2 9的一部分。此外’所描述之銜接狀況係會致使該球 根狀容室4 2連同閥球體4 3—起作用爲一個單向閥，而 閥球體4 3係被定尺寸以便能夠大致上在沒有辦法完全地 排除液體在容室4 2內逆流至調整器遞送管件4 7之中的 情況下進行妨礙作用。此一作用係藉由在閥球體4 3被液 體之逆流所迫使而抵住遞送端部4 8之時，使閥球體4 3 之表面抵住調整器遞送管件4 7之遞送端部4 8所得之機 械式密封而達成。此一單向或是防逆流功能係可以藉由使 該球體在遞送端部4 8的方向上偏斜（例如是藉由一個彈 簧）所幫助。 調整器遞送管件4 7之接收端部4 9係被構型以便包 括有一個銳利的頂端5 0，而該頂端5 0適合在調整器套 13 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事填寫本頁) -裝(Please read the note on the back S r, install --- P to write this page). Printed by the Consumers ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 1235672 A7 B7 Printed by the Consumer ’s Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 5. Description of Invention The tooth portion associated with the delivery mechanism and the storage mechanism is configured to allow the storage mechanism to move forward to engage the delivery mechanism, but to resist separation of the storage mechanism from the delivery mechanism. Preferably, the one-way valve system includes a bulbous container, and a bulb is provided in the bulbous container. Preferably, the one-way valve system is seated in the regulator sleeve. Preferably, the one-way valve system is seated within the delivery mechanism. Preferably, the one-way valve system is located in the storage mechanism. Preferably, the syringe further includes an actuator mechanism. Preferably, the actuator mechanism includes a plunger. Preferably, the actuator mechanism includes a coupling mechanism with a storage mechanism for releasably coupling a movable seal member located in the storage mechanism. Preferably, the syringe further includes a movable seal, and the movable seal defines a storage volume in the storage mechanism; the volume of the storage volume is based on the movable seal. The position of the piece in the storage mechanism is changed. Preferably, the actuator mechanism includes a movable barrier member. The movable barrier member functions to limit the actuation on the movable seal to one by the actuator mechanism. The preload is moved, whereby the movement of the plunger relative to the storage mechanism can be stopped at a preloaded position. Preferably, the preloaded movement is caused to be injected into the delivery mechanism by the substance located in the storage mechanism. This paper size is in accordance with China National Standard (CNS) A4 (210 x 297 mm) (Please read the precautions on the back first and fill out this page) i Pack. 1235672 A7 _____B7___ V. Description of Invention (Y) Better The preloaded position corresponds to the volume of the substance in the predetermined volume being the predetermined dose of the medicament. Preferably, the actuator mechanism can be detached from the movable seal in a manner that allows the actuator mechanism to avoid causing the movable seal to move in one direction, which will increase The volume defined in the storage mechanism. In a broader form of the invention, it is provided a needle assembly for use with the syringe described above. In a broader form of the invention, it is provided a plunger for use with the syringe described above. In a broader form of the invention, it provides a one-way valve for use with the syringe described above. In a broader form of the invention, it is provided an adjuster sleeve for use with the syringe described above. In a broader form of the invention, it is provided a kit of parts for use with the syringe described above. BRIEF DESCRIPTION OF THE DRAWINGS An embodiment of the present invention will now be described, in which: the first figure is an exploded side view of a single-use syringe assembly according to the first embodiment of the present invention; FIGS. 2A to 2I It illustrates the continuous steps of the assembly and use of the syringe for drug delivery in the first picture; and the third A-three L diagrams further illustrate the use of note 6 in the first picture (please read the note on the back first) Matters ^ Fill in this page) 1 ·· 1111111 Printed by the Intellectual Property Bureau of the Ministry of Economic Affairs, Consumer Cooperatives Paper size applicable to Chinese National Standard (CNS) A4 (210 X 297 mm) 1235672 A7 B7 V. Description of the invention (<) Steps for assembling and using a single-use syringe assembly. Graphical illustration of the symbols of the essential elements Printed by the Consumer Property Cooperative of the Intellectual Property Bureau of the Ministry of Economy 10 Single-use syringe assembly 11 Cylinder-shaped container 12 Storage capacity 13 Removable seal 14 Longitudinal axis 15 Inner wall portion 16 First end 17 Long plunger 18 Unsealed sealed connector / projection or stud latch 19 Plunger connector receptacle 2 0 Rear surface 2 1 End position 2 2 Container outlet 2 3 Film 2 4 Second end 2 5 First engaging tooth 2 6 Second engaging tooth 2 7 Tooth support unit 2 8 Slot 2 9 Joint sleeve 7 (Please read the notes on the back first and fill in this page) 1 丨 Binding · This paper size applies to China Standard (CNS) A4 specification (210 X 297 mm) 1235672 B7 V. Description of invention (L) 3 0 3 1 3 2 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 4 3 6 3 7 3 8 3 9 4 0 4 1 4 2 4 3 4 4 4 5 4 6 4 7 4 8 4 9 5 0 5 1 5 2 5 3 5 4 First End / Delivery End Needle Assembly Fill Connector Second End / Receiving End Spiral Shaped Channel First Tooth Barrier Inclined surface second tooth barrier oblong tip receiving end bulbous chamber Valve ball Long delivery channel Needle housing adjuster sleeve Engaged with tooth adjuster Delivery tube Receive end Tip protruding part Moveable stopper Braking position Hinged (Please read the precautions on the back first to fill out this page) n — ^ 1 —ϋ «_ϋ Yikou t · ala— ϋ 11 11 1 > 1 11 n Printed on the paper by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs, the paper size is applicable to China National Standard (CNS) A4 (210 X 297 mm) 1235672 A7 B7 V. Description of the invention (q) 5 5 Leading edge (brake) 5 6 Slot 5 7 Plunger body 6 0 Kit 6 1 Plastic bag Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs Detailed examples In the description, the term "liquid" is used hereinafter to describe the substance that is stored in the syringe assembly and ultimately delivered by the syringe assembly. It should be understood that in addition to delivering liquids, the syringe assembly can be used to deliver other materials, such as a mixture of liquid and solid suspended matter, a mixture of liquid, a mixture of fluid, or a combination of the two. Referring to the first figure, a single-use syringe assembly 10 according to a first preferred embodiment of the present invention is illustrated. In this example, the assembly 10 includes a storage mechanism, which is presented in the form of a cylindrical shaped container 11 having a storage capacity 12 defined therein. . The precise capacity of the storage capacity 12 is determined by a movable seal 13 which is always shaped along the cylindrical container 1 1 in a sealed, slidable manner The longitudinal axis 1 4 is moved 'while maintaining contact with the inner side wall portion 15 of the circle-shaped Gu Yi 11 1 in a sealed manner during the movement. The first end 16 of the cylindrical container 1 1 is suitable for receiving a long plunger 1 7 in a sliding manner 9 _ This paper size applies to China National Standard (CNS) A4 (21G x 297mm ^ (please First read the notes on the back 1 ^ Fill this page) Install aj ·. #. 1235672 A7 _ B7 V. Description of the invention (g) in it. The plunger 17 is a long one, and it is suitable to be along its longitudinal direction. Align with the longitudinal axis 14 of the cylindrical shaped container 11 and advance into the first end portion 16 of the cylindrical shaped container 11 so that the unfixed sealed connector 18 at its leading edge can Seated in a plunger connector receptacle 19 located in a square surface 20 behind the movable seal 13. In this example, the plunger connector receptacle 19 is in the form of a cavity Presented, it is suitable for receiving an unfixed sealed connector 18 presented in the form of a protrusion or a stud latch. The contents of the unfixed sealed connector 18 in the plunger connector receptacle 19 The placement system allows the plunger 17 to be easily removed simply by reversing the movement of the plunger 17 This is disengaged from the engagement state with the movable seal member 13 so that it can move away from the cylindrical shaped container 11 and away from the first end portion 16 along the longitudinal axis 1 4 'and in The moving direction of the plunger 17 is reversed from the movable seal 13 held in the cylindrical container 11. The plunger 17 has a sufficient length, so it can be used. To force the movable seal 13 along the longitudinal axis 14 to an end position 2 1 inside the cylindrical shaped container 1 1. In doing so, it is forced to be located in the storage capacity 12. The contents move in the direction of the container outlet 22. In this case, the cylindrical container 1 1 includes a frangible seal in the form of a thin film 23, which is formed in a cylindrical shape. The container outlet 1 2 is sealed and the container outlet 2 2 is sealed, so that the liquid in the storage capacity 1 2 can be prevented during the transportation. 10 This paper size applies to the Chinese National Standard (CNS) A4 (210 X 297 mm) " A ~ " one (Please read the note on the back first Matters needing attention 1 ^ Fill in this page)-Binding · Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economy 1235672 A7 B7 V. Description of the invention (1) The second end 2 4 (delivery end) of the cylindrical container 1 1 The combination has a delivery mechanism engagement mechanism, and in this example, it is presented in the form of a first engagement tooth portion 25 and a second engagement tooth portion 26, the first and second engagement tooth portions 25 and 2 6 Both are mounted on a substantially cylindrical tooth support unit 27, which itself extends outward from the second end portion 24 of the container 11. Referring to FIG. 3C and FIG. D, the tooth support unit 27 includes relative slots 28 therein, and the slots 28 have a sufficient width to allow the teeth 25 and 26 can perform at least limited inward deflection to help the teeth 25 and 26 to interface with the delivery mechanism, which will be described and discussed below. In this example, the delivery mechanism includes an engagement sleeve 29, which receives a delivery device at its first or delivery end 30, such as a needle assembly 31 or a perfusion connector 3 2 ′ or connected to other delivery systems that can be performed, for example, by a device of the type Lier. The engaging sleeve 29 is adapted to engage with the engaging mechanism of the delivery mechanism of the cylindrical shaped container 11 in a non-releasable manner at its second end or receiving end 33. In this example, the delivery The coupling mechanism of the mechanism includes the chewing teeth 25 and 26 and the container outlet 22 0, the teeth 25 and 26 are connected in a spiral molding channel 34, and the spiral molding channel 34 is located in the sleeve. The inner wall of the cylinder 2 9 is above or in the cylinder, and the cylinder-shaped container 11 is twisted relative to the sleeve 29. The paper size applies the Chinese National Standard (CNS) A4 specification (210 X 297 mm). ------------ Equipment—— (Please read the note on the back to write this page). Printed by the Consumers' Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 1236672 Printed by the Consumers ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs A7 B7 V. Description of the invention () When turning, it will advance along the passageway until it encounters the first tooth barrier 36. In such a situation, the further connection between the cylindrically shaped container 11 and the joint sleeve 29 is achieved by placing the cylindrically shaped container 11 along the longitudinal axis 14 in the direction of the sleeve 29. This is achieved by pushing up and forward, whereby the teeth 25 and 26 can travel upwards and over the inclined surface 3 7 of the barrier 36 (see the second figure A), thereby allowing the teeth 25 and 26 In the channel 34, it is possible to travel continuously with the continuous twisting movement of the container 11 relative to the sleeve 29. In this embodiment, the second toothed barriers 38 are further placed along the channel 34 from the first toothed barriers 36, and the barriers are also completed at the end and the completion. Must be crossed by the teeth 25 and 26 in a manner described in relation to the first teeth barrier 36. The sealing of the container 11 and the non-releasable engagement is achieved by the adjuster sleeve 29. . In this example, in addition to the sleeve 29, the delivery mechanism also includes a needle assembly 3 1 that is engaged with the first end of the adjuster sleeve 29 or the delivery end 30. . In a special case, the needle assembly 31 (refer to the first and second figures A) includes an elongated needle 39, which has a tip 40 at one of its delivery ends, It is suitable for helping to insert into living tissue. At a receiving end 41 of the needle 39, a bulbous container 42 is attached, and the bulbous container 42 is adapted to receive the valve ball 4 3 therein. The bulbous chamber 4 2 has the same size as the valve ball 4 3 12 --------------- (Please read the note on the back first and fill in this page) Order: This paper size Applicable to China National Standard (CNS) A4 (210 X 297 mm) 1235672 Printed by the Consumers' Cooperative of Intellectual Property Bureau of the Ministry of Economic Affairs Λ7 B7 V. Invention Description (u) A more sufficient volume, and it is based on a The valve ball 4 3 cannot prevent the liquid from moving forward in the direction of the elongated delivery channel 44 inside the needle 39, and is configured by the chamber 42. The needle housing 4 5 holds the receiving end portion 41 of the needle 39, and includes an adjuster sleeve engaging the tooth portion 46. The receiving end portion 41 of the needle assembly 3 1 is inserted into the adjuster sleeve. Among the delivery ends of the barrel 29, the adjuster sleeve engagement teeth 46 are mechanically engaged with the adjuster sleeve 29, so that the receiving end 41 of the needle assembly 31 can Let the delivery channel 44 including the bulbous chamber 4 2 be placed in fluid communication with the delivery end of the adjuster delivery tube 47 and held in the adjuster sleeve 29, The adjuster delivery tube 47 is housed in the adjuster sleeve 29 and forms a part of the adjuster sleeve 29. In addition, the described connection condition will cause the bulbous chamber 4 2 together with the valve ball 4 3-to function as a one-way valve, while the valve ball 4 3 is sized so that it can be ruled out completely in no way The liquid counteracts in the case where the liquid flows back into the regulator delivery tube 47 in the chamber 42. This effect is obtained by making the surface of the valve ball 4 3 against the delivery end 48 of the regulator delivery tube 47 when the valve ball 4 3 is forced against the delivery end 48 by the countercurrent of the liquid. Mechanical seal. This one-way or anti-backflow function can be assisted by deflecting the sphere in the direction of the delivery end 48 (for example by a spring). The receiving end portion 4 9 of the adjuster delivery tube 47 is configured to include a sharp tip 50, which is suitable for the adjuster sleeve 13. The paper size applies the Chinese National Standard (CNS) A4 specification ( 210 X 297 mm) (Please read the notes on the back to complete this page)-Pack
I 1235672 經濟部智慧財產局員工消費合作社印製 B7 五、發明說明（\X) 筒2 9與容器1 1進行銜接期間能夠刺穿薄膜2 3，從而 提供一種液體連通的通道而從谷益1 1之儲存谷積1 2處 、通過調整器遞送管件4 7、通過球根狀容室4 2、並且 通過針頭遞送通道4 4、而通過該針頭尖端4 〇。 將爲熟習此技者了解的是’至少調整器套筒2 9係會 遭受到從容器1 1處脫離的困難’此係由於位在阻隔件3 6及3 8之遞送側邊上的突出部分5 1所致，其係與位在 銜接齒部2 5及2 6之接收側邊上的相應突出部分5 2以 一種平面方式相銜接。 在一種特殊形式之中’柱塞1 了係包括有可移動式阻 隔件5 2，該可移動式阻隔件5 2係以一種樞轉方式被連 接至該柱塞1 7，以便在一個制動位置處執行一種預裝塡 制動器的功能，其係可防止柱塞1 7滑動進入容器1 1中 而超過一個預先決定之插入限制。在第圖以及第三Η 圖中所顯示之可移動式阻隔件5 2係處於其制動位置5 3 之中。 該可移動式阻隔件5 2係可以繞著鉸接線5 4而旋轉 ，以使其前引（制動）邊緣5 5能夠置放在柱塞主體5 7 之狹槽5 6內而處於一個非制動位置中，在此位置中，其 不再銜接容器1 1之第一端部1 6 ’從而容許柱塞主體5 7能夠前進至容器1 1之中’以便致使可移動式密封件1 3讓容積縮小’以便迫使被容置於該容積中的液體能夠通 過容器出〇 2 2、通過調整器遞送管件4 7、通過遞送通 道4 4、而從針頭3 9的尖端4 〇處離開。 14 丨 --- (請先閱讀背面之注意事項寫本頁) )aT·- 本紙張尺度適用令國國家梯準（CNS)A4規格（210 x 297公釐） 1235672 A7 B7 五、發明說明（） 在使用中，參照第二a圖至第二I圖以及第三A圖至 第三L 11 ’ 一個想要使用單次使用式注射器組件1 〇的使 用者係首先將組件之諸部件進行組裝，藉由採用一個將一 液體形式藥劑裝塡於儲存容積1 2中之容器1 1，該儲存 容積12亦即包括有針對所欲進行之特殊使用之預定藥劑 劑量一個預定容積。接著，使用者（在圖示中並未顯示出 來）係得以對遞送機構進行接觸並對其進行組裝，此係藉 由將閥球體4 3插入至針頭組件3 1的球根狀容室4 2之 中所達成（此一步驟係可以在製造程序中並且在遞送至最 終使用者之前予以施行），接著將針頭組件31以一種前 述並可從第三C圖以及第三D圖所淸楚看到的方式連接至 調整器套筒2 9的遞送端部。 使用者接著以一種非可釋放的方式將包括有該已組裝 之針頭組件3 1及調整器套筒2 9的遞送機構連接至容器 1 1之遞送端部，此係藉由一種如同上述之迫使、扭轉之 動作所進行。 藉由如此進行，薄膜2 3係被調整器遞送管件4 7之 接收端部4 9所穿刺，從而將儲存容積1 2帶至與針頭組 件3 1成一種液體銜接狀態。 使甩者接著將柱塞1 7 (而可移動式阻隔件5 2係處 於制動位置5 3中）插入至容器1 1之第一端部1 6之中 ，以使得未固定式密封連接器18能夠銜接在柱塞連接器 容座1 9中，以便迫使可移動式密封件1 3沿著軸線1 4 15 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事填寫本頁) 裝 · 經濟部智慧財產局員工消費合作社印製 1235672 經濟部智慧財產局員工消費合作社印製 A7 B7 五、發明說明（j) 而移動於一遞送方向上，直到可移動式阻隔件5 2遭遇到 容器11爲止。 在到達此一預裝塡位置之中，一個來自於儲存容積1 2內之液體之預定的預裝塡容積將通過調整器遞送管件4 7並且進入至遞送通道4 4之中，從而將空氣從這些通道 處移去，並且確保該整個針頭組件3 1能夠完全地被充塡 預備好能夠加以使用。 經由設計，可移動式密封件1 3的此一位置將爲準確 地界定出在儲存容積12內的預定藥劑劑量之預定容積的 位置。 使用者現在係將可移動式阻隔件5 2從該制動位置處 開始移動，並且繼續著柱塞1 7之移動進入至容器1 1內 而到達其所允許之通道的完全範圍，亦即到達可移動式密 封件13於其遞送端部處遭遇到容器1丨之壁部的位置點 處。在此一位置點處，預定藥劑劑量之預定容積將經由尖 端4 0而予以遞送。 該柱塞1 7係可以接著被抽回，而不會干擾到可移動 式密封件13 (如同在上文中已然描述者）。 將能夠了解到的是，此一示例型配置之不同變化樣式 係可以被完成而仍將落於本發明之範疇之中。舉例來說， 該閥體機構係可以被製造成爲一個完全獨立的個體，用於 獨立地耦合至注射器組件之中。在一個特別的實施例之中 ，該閥體機構係可以被插入至該針頭組件以及該儲存機構 之間。 16 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） ϋ n I ϋ n n ί «ϋ n I n n I 士失· i ϋ (請先閱讀背面之注意事項d填寫本頁) . •f· 1235672 A7 __B7_ 五、發明說明（γ<) 同樣地，易破型密封件係可以採用一種可機械式操作 之閥體或其他執行一種均等功能之裝置的形式。 請 先 閱 讀 背 以上僅描述了本發明的某些實施例，對熟習此項技藝 者而言相當明顯的是在不背離本發明之範疇及精神之下係 可對本發明進行修正。I 1235672 Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economics B7 V. Description of the invention (\ X) The tube 2 9 can pierce the film 2 3 during the connection with the container 1 1 to provide a fluid communication channel from Gu Yi 1 There are 1 storage troughs 1 of 2, the tube 4 is delivered through the regulator, 7 is through the bulbous chamber 4 2 and the needle delivery channel 4 4 is passed through the needle tip 4 0. One skilled in the art will understand that 'at least the adjuster sleeve 2 9 series will suffer from the difficulty of detaching from the container 1 1' due to the protrusions located on the delivery sides of the barriers 36 and 38. It is caused by 51 that it is connected with the corresponding protruding portion 52 on the receiving side of the engaging teeth 25 and 26 in a planar manner. In a special form, the 'plunger 1' system includes a movable barrier 5 2 which is connected to the plunger 17 in a pivotal manner so as to be in a braking position A pre-installed cymbal brake function is implemented here to prevent the plunger 17 from sliding into the container 11 beyond a predetermined insertion limit. The movable barrier 5 2 shown in the figure and the third figure is in its braking position 5 3. The movable blocking member 5 2 can be rotated around the hinge line 5 4 so that the leading (braking) edge 5 5 can be placed in the slot 5 6 of the plunger body 5 7 in a non-braking state. In this position, it no longer engages the first end portion 16 of the container 11 to allow the plunger body 5 7 to advance into the container 1 1 'so as to cause the movable seal 1 3 to allow volume Zoom out 'so as to force the liquid contained in the volume to exit through the container 02, to deliver the tubing 47 through the regulator, through the delivery channel 44, and leave from the tip 40 of the needle 39. 14 丨 --- (Please read the notes on the back to write this page)) aT ·-This paper size is applicable to the national standard (CNS) A4 size (210 x 297 mm) 1235672 A7 B7 V. Description of the invention ( ) In use, refer to Figures 2a to 2I and Figures 3A to 3 L 11 'A user who wants to use the single-use syringe assembly 1 0 first assembles the components of the assembly By using a container 11 containing a liquid form medicine in a storage volume 12, the storage volume 12 also includes a predetermined volume of a predetermined medicament dose for a particular use intended. Next, the user (not shown in the figure) is able to contact and assemble the delivery mechanism by inserting the valve ball 4 3 into the bulbous chamber 4 2 of the needle assembly 31 (This step can be performed during the manufacturing process and before delivery to the end user), and then the needle assembly 31 can be seen as shown in Figures 3C and 3D Attach to the delivery end of the adjuster sleeve 29. The user then connects the delivery mechanism including the assembled needle assembly 31 and the adjuster sleeve 29 to the delivery end of the container 11 in a non-releasable manner by forcing it as described above. Twisting action. By doing so, the film 23 is punctured by the receiving end 49 of the regulator delivery tube 47, thereby bringing the storage volume 12 to a liquid-engaged state with the needle assembly 31. The shaker then inserts the plunger 17 (while the movable barrier 5 2 is in the braking position 5 3) into the first end 16 of the container 11 so that the unsealed sealed connector 18 Can fit into the plunger connector holder 19 to force the movable seal 1 3 along the axis 1 4 15 This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) (please first Read the notes on the back and fill in this page) Equipment · Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs Printed 1235772 Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs Printed A7 B7 V. Invention Description (j) Move in a delivery direction until The movable barrier 5 2 meets the container 11. Upon reaching this pre-packed position, a predetermined pre-packed volume from the liquid in the storage volume 12 will be delivered through the regulator tube 4 7 and into the delivery channel 44, thereby removing air from The channels are removed and it is ensured that the entire needle assembly 31 can be fully filled and ready for use. By design, this position of the movable seal 13 will be a position that accurately defines a predetermined volume of a predetermined medicament dose within the storage volume 12. The user now moves the movable barrier 5 2 from the braking position, and continues the movement of the plunger 17 into the container 11 to reach the full range of the permitted passage, that is, the The point at which the movable seal 13 meets the wall portion of the container 1 丨 at its delivery end. At this point, a predetermined volume of the predetermined medicament dose will be delivered via the tip 40. The plunger 17 series can then be withdrawn without disturbing the removable seal 13 (as already described above). It will be appreciated that different variations of this exemplary configuration can be accomplished and still fall within the scope of the invention. For example, the valve body mechanism can be manufactured as a completely separate entity for independent coupling into a syringe assembly. In a particular embodiment, the valve body mechanism can be inserted between the needle assembly and the storage mechanism. 16 This paper size is in accordance with China National Standard (CNS) A4 (210 X 297 mm) • f · 1235672 A7 __B7_ V. Description of the invention (γ <) Similarly, the fragile seal can take the form of a mechanically operable valve body or other device that performs an equal function. Please read first. The above only describes some embodiments of the present invention. It is quite obvious to those skilled in the art that the present invention can be modified without departing from the scope and spirit of the present invention.
I 訂 經濟部智慧財產局員工消費合作社印製 7 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐）Order I Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 7 This paper size applies to China National Standard (CNS) A4 (210 X 297 mm)