TW537911B - Sealed back pressure breathing device - Google Patents

Abstract

A hand-held breathing device for use by patients having respiratory problems creates a sealed backpressure in the airways of the patient by creating resistance to exhalation. A peep valve is mounted inside a hollow body, and a pre-set compression spring is mounted between the valve and an adjustable cap or cam lever in the main body of the device. A pair of valve openings extend through the wall of the main body, one opening serving as an intake port for inhaling of air by the patient and the second port for exhalation of carbon dioxide. An intake valve is mounted inside the body between a normally open end of the device and the exhalation valve. In one of the embodiments, the device is attached to a nebulizer to facilitate buildup of positive pressure and delivery of medication to the patients' lungs.

Description

537911 V. Description of the invention (1)

"Invention" I The present invention relates to a lung device that assists a patient. The device can be used alone, and the device can be used with a Nebulizer to fit into the patient's respiratory tract (A i r w a y). Breathing device in particular, the user produces positive and negative pressure in the airway (PositL · the invention that keeps the airway open and returns to normal ^ _ sprayer is the most widely used to assist disposition. When encountering asthma Seizures, emphysema, or similar medications are delivered to the respiratory tract to exert a medicated dose inhalers (Medium ered dose inhalers, tight airways, medical personnel in accordance with conventional treatment behavior. The sprayer squeezes the liquid medicine into an extremely misty form 'After delivering the drug to the patient's lungs and conventionally, a nebulizer is used to deliver the breath (D i 1 at 〇r). For example, when a patient ^ patient's carbon dioxide concentration value usually helps Deliver a large amount of necessary dilators to the lungs of the patient. The dilators described above include a type of lung bronchial receptor that interacts with each other to clear the device that may include steroids and sulfates. The muscle is used. Or, the medicine is used to deliver drugs. The present invention relates to a breathing device used to breathe. When suffering from the symptoms of respiratory problems mounted sprayers help in the emergency room, when given MD Is) can not relax patients will use the sprayer Medical tiny drops of liquid, similar to thin within the respiratory tract. When the airway dilator t is delivered to the emergency room, this is quite high. The nebulizer can assist and assist in removing gas from chemicals, and can interact with the patient's respiratory tract. This chemical% (Magnesium

537911 V. Description of the invention (2) sulfate), and bronchodilators (Bronchodilator). However, the efficiency of conventional sprayers is quite low and may require up to eight hours of treatment. When a patient is in critical condition and must receive emergency treatment, an ambu bag equipped with a mask will often come in handy. The mask can seal the patient's nose and mouth, and when the auxiliary bag is squeezed, the positive pressure generated will force the drug into the respiratory tract. There are many areas in which this medical procedure is incomplete. For example, air may be squeezed into a patient's stomach, causing flatulence and vomiting, and vomit may be drawn into the lungs, which increases the risk of lungs inhaling foreign bodies. Some patients are more severe and cannot be adequately assisted with a sprayer or wake-up breathing aid. These patients therefore require the use of a ventilator. A respirator is an artificial breathing machine used to assist or control breathing. It works in conjunction with an Endotracheal tube that penetrates the patient's trachea. The positive pressure generated by using a respirator is much higher than the positive pressure generated by using a sprayer equipped with a resuscitation breathing aid bag. Therefore, too much air is often squeezed into the patient's lungs. If the patient uses the respirator for too long, the patient will only be able to breathe through the respirator in the future. However, excessive use of artificial respirators will cause the patient's respiratory muscles to atrophy, and the atrophic respiratory muscles cannot recover. Therefore, the present invention is directed to the problems of the conventional technology; a hand-held device can be provided for use by patients, and can also be used by medical personnel to exercise respiratory muscles, or used in conjunction with a sprayer to deliver drugs.

5KEATY200201TW.ptd Page 6 537911 V. Description of the invention (3) Summary of the invention Therefore, one object of the present invention is to provide a sealed, calibrated reverse pressure device for generating positive pressure to suffer from asthma, emphysema And other respiratory diseases in patients with restricted airways. Another object of the present invention is to provide a hermetically sealed reverse pressure breathing device for use with a nebulizer. The device can be set in advance to generate the required amount of pressure and deliver medication to restore the patient's normal breathing. A further object of the present invention is to provide a breathing apparatus which can help patients exercise their breathing muscles. Another object of the present invention is to provide a portable and lightweight device having a positive pressure for regulating a positive pressure generated in a patient's respiratory tract. The portable device includes a hollow body. The body has an exhalation control valve. The exhalation control valve is fixed on a support frame inside the body. The hollow body provides two unobstructed openings: an air inlet and an air outlet. An intake control valve can be a simple component, such as a rubber gasket. The suction control valve is fixed in the hollow body, and is located between the suction control valve and the open end. The open end may be provided with a toothed sleeve, or a size and shape suitable for being connected to a sprayer through a manifold. The closed end of the hollow body is provided with a device for adjusting the positive pressure. In a specific embodiment, the adjusting device is a cover and is threaded with the hollow body. The adjustable cover is threadedly engaged with the main body. In a second embodiment, the adjustment method is an adjustable cam lever. A compression spring is fixed between the exhaust control valve and the adjustment device. The calibration of the device can be set to a predetermined

5KEATY200201TW.ptd Page 7 537911 V. Description of the invention (4) Pressure, the pressure range between 5 cm and 20 cm water column height is the most suitable. The advantages and spirit of the present invention can be further understood through the following detailed description of the invention and the accompanying drawings. Detailed description The attached drawings will be described in detail below, and the reference numeral 10 refers to a device according to a first embodiment of the present invention. The device 10 includes an elongated hollow body 12. The main body 12 includes a cylindrical main portion 14, an integrally continuous central portion 16 of a vertebra, and a toothed sleeve 18. The sleeve 18 is only connected to the central portion 16 of the vertebra. A central opening 20 is located in the body 12 and extends from an open end 22 of a toothed sleeve, through the toothed sleeve 18, the middle cone portion 16 and the hollow body 12. An adjustable bolt cover 2 4 abuts the closed end 2 6 of the main part 1 4. The inner wall of the cover 24 is provided with a thread 2 8. The thread 2 8 can be matched with the thread 30 on the outer wall of the other end 2 6. A center inspection 32 is formed in the cover 24 and extends outward from an inner end 34 of one of the covers 24. Please refer to FIG. 3 for a clearer understanding of the end 34 forming an annular shoulder to provide a first adjacent surface against the adjacent compression spring 40. This section will be described in detail below. An air inlet 4 2 penetrates the inner wall of the hollow body 12. An air outlet 4 4 is formed in the main portion 14 and is separated from the air inlet 42. An exhaust control valve (E X h a k a t i ο ν a 1 ν e) 5 0 is disposed between the air inlet 4 2 and the air outlet 4 4. For details, refer to FIG. 7. Exhalation control valve

5KEATY200201TW.ptd Page 8 W / 911 V. Description of the invention (5) Power furnace with positive end-expiratory pressure (PEEP) attached The first embodiment of the present invention and the second and b 髀 f are also known as PEEP valve. The valve 50 is the same valve, so in the detailed description ^ = the exhalation control example in the embodiment, it will be omitted and will not be described in detail = the second one is a 50-degree exhalation control valve fixed to an ip plus a branch. The frame (or frame) 52 is installed in the main; :: 彳, / is the frame 52, which should be within 4 points and 4 points. The supporting block (or frame) 52 is provided with a ring-shaped protrusion 54 which engages with the inner wall of the main portion 14 by friction. Yue Luo within the protrusion 54 provides a second adjacent surface to the compression spring 40. -The inwardly extending shoulder 56 is formed on the inner wall of the main portion 14 and is adjacent to the connection region between the main portion 14 and the middle cone-shaped portion M. When a force is applied to the shoulder portion 56 along with the support frame 52 along the breath control valve 50, the shoulder portion 6 will form a resistance. Please refer to Figure 9, an intake control valve 60 is fixed in this main part! 4 " Between the open end 2 2 of the gear sleeve and the supporting frame 5 2. The inhalation control valve 60 can be a simple component, such as an elastic rubber gasket, which is opened into a one-way valve 'and is opened during the inhalation process. The circular suction control 阙 f 0 has a diameter smaller than the inside diameter of the opening 20 of the main part 14, allowing some empty milk to move around the suction control valve 60. The suction control valve (or cover) 60 is made of a material such as latex. When pressure is applied to the piston and the compression spring 4o, the suction control valve (or cover) 60 covers the entrance and exit of the piston / support 50, but passes through the opening in the support 5 The suction control valve (or cover) 60 is open to allow fresh air to be drawn in.

537911 V. Description of the invention (6) When the device 10 is assembled, at least one end of the compression spring 40 firmly bears against the end 34 of the annular shoulder and surrounds the center pin 32. The second end of the compression spring 40 is abutted against the exhaust control valve 50 fixed in the support frame 52. Under normal conditions, a force is applied to the exhaust control valve 50 in the closed position as shown in FIG. The exhalation control valve 50 is opened when air is inhaled, as shown in Fig. 8, but it provides a preset resistance to the airflow during exhalation. When the user needs to exercise his breathing muscles, or simply dilate the airway, he uses his lips against the open end 22 of the sleeve 18. During the suction process, air flows from the suction port 42, passes through the suction control valve 50, surrounds the suction control valve 60, and enters the open end 22 of the toothed sleeve 18. When exhaling, the airflow flows in the opposite direction, it flows from the open end 22, surrounds the intake control valve 60, and resists the impedance of the compression spring 40, and then enters the directional exhaust port 44. In order to expel the air out of the main body 12, the user must apply sufficient pressure to the compression spring 40, and then move the support frame 52 to a position away from the air outlet 44 to allow the air to be exhausted. Because the compression impeachment 40 provides resistance to the exhalation control valve 50, a back pressure will be generated in the patient's respiratory tract, forcing the patient to use more force when exhaling, thereby strengthening the patient's breathing function muscle. The cover 24, which is in contact with the compression spring 40, can be more or less screwed onto the main body 12 to allow adjustment of the pressure generated by the positive pressure to a range between 5 and 20 cm of water column height. Although other pressure adjustments can be easily achieved if needed, the pressure ranges described above have been found to be appropriate for most patients. Next, the second specific embodiment shown in FIGS.

5KEATY200201TW.ptd Page 10 537911 V. The invention description (7) shows the sprayer attachment device 70. The device 70 comprises an elongated cylindrical body 72, which has an open end 74 and a closed end 76. An adjustable cam lever 78 is fixed to a bracket connected to the closed end 76, thereby allowing adjustment of the pressure required for the opening and closing of the exhaust control valve fixed inside the main body 72. The above pressure can be adjusted to a desired value, for example, a pressure range between 5 and 10 cm water column height, depending on the user's situation. The pressure can be adjusted by adjusting the position of the cam lever 78. For example, a first position is a pressure indicating a height of 10 cm of water. By turning the cam lever 78 in the opposite direction, the user can adjust the degree of compression of the pressure spring 96, thereby generating a pressure of about 5 cm of water column height. Of course, the rotation of the cam lever 78 can be corrected to correspond to the desired pressure range, and is installed at different positions of the main body 72, and the setting of the pressure range is indicated by an appropriate scale. The main body 72 is provided with a directional air inlet 80 and a directional air outlet 82. The open end 7 4 is frictionally connected to a manifold 8 4. The manifold 8 4 carries a toothed sleeve 8 6 and a common sprayer 8 8. The manifold 84, the toothed sleeve 86, and the sprayer 88 are not components of the present invention, so they are shown by dotted lines in FIG. Please refer to FIG. 5 and FIG. 6, which show the detailed structure of the inside of the device 70. It can be seen from FIG. 5 that the main body 72 is provided with a central hole 90, and the central hole 90 is a closed wall 92 extending from the open end 74 to the closed end 76. The cam lever 7 8 is rotatably fixed to a bracket 7 7 shown in FIG. 6, and the bracket 7 7 is firmly connected to the closing of the closed end 7 6.

5KEATY200201TW.ptd Page 11 537911 V. Description of the invention (8) Wall 92. The piston 94 can move only a small displacement in the central hole 90 to adjust the compression degree of a compression spring 96. The compression spring 9 6 is fixed between the piston 94 and the exhaust control valve 98. The exhalation control valve 98 is similar to the exhalation control valve 50, so the detailed description of the exhalation control valve 98 is omitted here. The exhalation control valve 98 generates positive and negative pressure by forcing the patient to exhale against the compressed impeachment 96. An inhalation control valve similar to the inhalation control valve 60 is disposed in the main body 72 and is located between the open end 74 and the exhalation control valve 98. During the intake of air, the air flows in the direction shown by arrow 100 through the suction port 80, through the exhaust control valve 98 and the suction control valve 60. During the process of exhaling or exhausting, the air is directed against the rubber gasket, or the cap-shaped suction control valve 60, the rubber gasket (or the cap-shaped suction control valve 6) 0) Normal state is to close the entrance / exit of the piston / support frame. By continuously exhaling, the patient can move the support frame that resists the resistance of the compression spring 96 to move away from the air outlet 82, so that the flow of the gas flow is in the direction shown by the arrow 102. It flows through the exhaust control valve 98 and flows through the exhaust port 82, as shown in FIG. Once the adjustable cam lever 78 is adjusted to produce the required resistance to the flow of air, the additional device 70 is fixed to the manifold 84 and completes the connection with the sprayer 88. A certain amount of drug 104 is dripped into the nebulizer 88 and mixed with the air flowing through the manifold 84, flows to the tooth set 86, and is delivered to the patient's respiratory tract. The medicine in the form of minute droplets is formed by the aerosol-forming member 10 6 intercepting the airflow flowing through the duct-shaped body 7 2. The aerosol formed is mixed with the inhaled airflow and is passed

5KEATY200201TW.ptd Page 12 537911 V. Description of the invention (9) It is sent to the patient's respiratory tract, expands the patient's respiratory tract, and slows the onset of asthma, or other respiratory problems of the patient. During the process of exhaling or inhaling, for better operation, the patients keep their mouths firmly around the tooth sets 18 and 8 6 so that the devices 10 and 70 are closed. The open end allows effective drug delivery and gas release. When the patient exhales, the exhalation control valve tends to dilate the patient's airway and avoids alveolar collapse by generating a positive and negative pressure. When the air is forced to be discharged only through the exhaust control valve, the exhaust control valve is set in advance by a cover 24 or by the cam lever 78 to provide resistance, and the exhausted air cannot be exhausted through the intake port. , And must flow through the exhaust port 4 4 or 8 2. By keeping the forward and reverse pressure sealed inside the device 10 and device 70, the patient's airway will be unobstructed to restore normal breathing. Once the pressure in the inflamed alveolar sac is the same as the pressure in the trachea, the drug will penetrate more easily into the respiratory tract and cause the respiratory tract to expand. The device 10 and the device 70 limit the discharge of carbon dioxide through the air outlet 44 or the air outlet 82, thereby reducing the concentration of carbon dioxide in the blood of the patient. When these restricted gases are expelled from the lungs, the lungs can develop inhalation pressures that have a slight effect on the patient. Once the respiratory tract expands, it establishes a pyramidal effect (Pyramid e f f e c t), thereby increasing the large amount of required oxygen flow. The user equalized pressure in all areas of the lungs and increased lung volume, thereby experiencing a longer exhalation process. Once the airways are dilated, air enters and exits the lungs.

5KEATY200201TW.ptd Page 13 537911 V. Description of Invention (ίο) Improvement. The lungs are not over-inflated, and fresh air is easier to get in and out of the lungs. In addition, if the additional device 70 is used, the medicine 104 sprayed by the nebulizer will reach the lungs, respiratory tract and other parts to be improved more effectively. As a result, the patient's collapsed or obstructed airway will continue to be unobstructed, enabling more accurate drug delivery. In this way, fewer drugs can achieve better results. The present invention is applicable to patients suffering from asthma or emphysema. Many patients with asthma are often unable to take medication easily in the event of an asthma. Sudden onset can cause anxiety and exacerbate asthma. Patients may have suffocation before taking the medicine. With the small portable device of the present invention, it can come in handy. The patient can recover at least part of his breathing function and reduce the patient's anxiety. During emphysema, the ends of the bronchi will continue to fail and spread. The alveolar wall will slowly deteriorate over time. As the area of the alveoli decreases and the surface area of gas exchange decreases, the elasticity of the lung tissue will also decrease. Lack of elasticity in the lungs can lead to inappropriate lung atrophy and fatigue in the respiratory muscles. The lungs cannot stretch properly and return to their original position. In such cases, patients are usually advised to use sigma mouth breathing (P ur s e d 1 i p s breathing). With this sealed back pressure device (10 or 70), patients with emphysema can increase the transfer of air from the lungs and expel carbon dioxide from the blood. With the back pressure generated by device 10 and device 70, bronchial and alveolar collapse can be avoided. Results in less overinflated lungs, making the patient better

5KEATY200201TW.ptd Page 14 537911 V. Description of the invention (11) Inhale and exhale sufficiently to deliver a larger area of the drug to the damaged tissue. In addition, the sealed positive pressure will help keep the alveoli and airways open, and let the extra carbon dioxide be released into the atmosphere. The effective elimination of gases in the lungs and blood will improve the patient's physiological function and allow more oxygen to be delivered to the patient's lungs. It can be imagined that although the preferable pressure setting range of the device 10 and device 70 is about 5 cm to 20 cm of water column height, the device 10 and device 70 can be set in advance to exceed the values indicated above. Especially for patients with quite severe respiratory tract collapse and other problems. It is conceivable that the device of the present invention can be used to exercise the patient and restore their ability to normal breathing. The device 10 of the first specific embodiment can particularly confirm the above-mentioned claims. It is also conceivable that a nose clip and / or a molded cushion tooth set can be used in conjunction with the tooth set to ensure that the patient's lips can achieve a better seal around the tooth set. The device of the present invention is manufactured using currently available materials, such as plastic materials and light metals, so the manufacturing cost is not high. The compression springs (40 and 96) should be made of materials with sufficient strength to withstand compression and extension of the device during use. It is conceivable that the tooth set 18 can be manufactured to be detachably engaged with the main body part 14 if necessary. In the above case, the device 10 and the separable tooth set 18 can be carried in a lightweight space away from the pocket of the user, and when in use, engage with the remaining components of the device. The device 70 can be connected to a metered-dose inhaler, instead of a nebulizer, if needed. In the above case, a small medicine storage space (Spacer) will

5KEATY200201TW.ptd Page 15 537911

5KEATY200201TW.ptd Page 16 537911 Simple illustration of the drawing Simple of the drawing—JL1— FIG. 1 is a perspective view of an additional device according to the first embodiment of the present invention. Figure 2 is a longitudinal sectional view of the device shown in Figure 1, which also shows that the adjustable cover is threadedly engaged with the main body. Fig. 3 is a longitudinal sectional view of the device according to a first embodiment of the present invention, and the figure also shows that the adjustable cover is separated from the main body. Figure 4 is a perspective view of a device according to a second embodiment of the present invention, the device being coupled to a manifold, and through the manifold, the device is connected to a sprayer. Fig. 5 is a longitudinal sectional view of the device of the second embodiment of Fig. 4, which also shows that the device is equipped with an adjustable cam lever. Fig. 6 is a longitudinal sectional view of a device according to a second embodiment of the present invention, and the figure also shows the flow of air during exhalation and inhalation. Fig. 7 is a detailed structure diagram of a support frame provided on an exhaust control valve. Figure 8 Front view of the air inlet of an exhalation control valve. Figure 9 is a detailed structure diagram of an intake control valve. Explanation of Symbols 12> 72 Hollow body 16 Cone central part 20 V24 Bolt cover 28> 30 Thread 1 0: Device 1 4: Main part 1 8, 8 6: Gear sleeve 2 2: Gear sleeve opening End 2 6: closed end

5KEATY200201TW.ptd Page 17 537911 Brief description of the diagram 32 Center bolt 34 40, 96 Compression spring 42 > 80 44 > 82 Exhalation V 50 > 98 52 Support frame (or frame) 54 56 Shoulder 60 extending inwardly 60 70 Sprayer attachment 74 76 Closed end 78 84 Manifold 88 90 Center hole 92 94 Piston 100 > 102 104 Drug 106 Internal end suction port exhalation control valve annular protrusion Inhalation control valve open end cam lever sprayer Closed-wall arrow aerosol-forming member

5KEATY200201TW.ptd Page 18

Claims (1)

537911 VI. Application Patent Scope 1. A sealed reverse pressure device for assisting a patient with a respiratory function, the device includes: an elongated hollow body including an open end, a closed end, and an inhaler Port and an air outlet; a one-way air outlet control valve, which is fixed inside the hollow body, the air outlet control valve is used to allow the discharged air to be discharged through the air outlet; a compression spring, the compression bomb system Fixed between the exhalation control valve and the closed end, the compression spring is used to adjust the resistance against the airflow expelled by the patient; and an adjustment device is fixed to the closed end of the hollow body The adjusting device is used for adjusting the compression of the compression spring. 2. The device according to item 1 of the scope of patent application, wherein the adjusting tool includes a cover, the cover is detachably fixed to the closed end, and the cover provides a first abutting surface for The compression spring. 3. The device according to item 2 of the scope of the patent application, wherein the exhaust control valve is supported by a frame, the frame is fixed to the hollow body, and the frame provides a second abutting surface to the compression spring. 4. The device according to item 2 of the scope of patent application, wherein the cover is engaged with the closed end of the hollow body by a thread. 5KEATY200201TW.ptd Page 19 537911 6. Application for patent scope 5. The device described in item 2 of the patent scope, wherein the cover can adjust the compression spring to maintain a positive and negative pressure between 丨The range between 3 and 20 cm south of the water column. The device described in item 3 of the patent application, wherein the hollow system provides a ring-shaped shoulder that extends to the hollow body. Inside a central channel and in which the frame contacts the shoulder, thereby preventing the frame from sliding toward the open V end. 7. Please refer to the device described in item 1 of the patent, in which the open end is provided with a tooth sleeve for the patient's lips to engage with the open end. 8. The device described in item 1 of the patent scope further includes an intake control valve which is fixed between the open end and the exhaust control valve. 9. The patent scope The device described in item 8, wherein the suction control valve includes a rubber pad. 0 ^ The device described in item 1 of the patent scope, wherein the adjustment tool includes a sliding piston j The hollow body is movable inside, and the piston provides an abutment surface to the compression spring. 1 As described in the patent, please refer to the device described in item 9 of which, one of which can be adjusted 5KEATY200201TW.ptd Page 20 537911 6. Scope of patent application The cam lever is fixed on the sliding piston to adjust the resistance against an exhaled airflow. 12. The device as described in item 10 of the scope of patent application, wherein the cam lever is adjustable to maintain a range of positive and negative pressures between 5 and 10 cm of water column height. 1 3. The device according to item 1 of the scope of patent application, wherein the hollow body system is coupled with a sprayer, and the connection between the hollow body and the sprayer is used for the hollow body and the sprayer. A fluid transfer channel was established between them to deliver the drug to the patient's respiratory tract. 14. The device according to item 13 of the scope of patent application, wherein the open end of the hollow body is fixed to the sprayer in a detachable manner. 15. A sealed back pressure device to assist a patient's breathing function, the device comprising: an elongated hollow body, the body including an open end, a closed end, an air inlet and an air outlet; A one-way exhaust control valve, which is supported by a support frame and fixed inside the hollow body, the exhaust control valve is used to allow exhaust gas to be discharged through the exhaust port; a compression spring, the compression spring The compression spring is fixed between the exhalation control valve and the closed end. The compression spring is used to maintain a forward and reverse pressure, and is used to 5KEATY200201TW.ptd Page 21 537911 6. The scope of the patent application adjusts the resistance against the airflow spit out by the patient; and an adjustment device is fixed on the closed end of the hollow body. The adjustment device is used To adjust the compression of the compression spring, the adjustment device includes a cover, which is detachably fixed to the closed end, the cover provides a first abutting surface to the compression spring, and the support frame A second abutting surface is provided to the compression spring. 16. The device according to item 15 of the scope of patent application, wherein the open end is provided with a tooth sleeve for the patient's lips to engage the open end. 17. The device according to item 15 of the scope of patent application, further comprising an intake control valve, the intake control valve is fixed between the open end and the exhaust control valve. 18. The device according to item 15 of the scope of patent application, wherein the cover is engaged with the closed end of the hollow body by a thread. 19. The pressure device according to item 15 of the scope of patent application, wherein the cover is capable of compressing the compression impulse to maintain a range of positive and negative pressure between 5 and 20 cm of water column height. 20. The device according to item 15 of the scope of patent application, wherein the hollow system provides an annular shoulder, the shoulder extends into a central channel formed by the hollow body, and wherein the support frame Touch the shoulder to prevent 5KEATY200201TW.ptd Page 22 537911 6. Scope of patent application Stop the support frame from sliding toward the open end. 21. A sealed reverse pressure device for assisting a patient's breathing function, the device includes: an elongated hollow body, the body including an open end, a closed end, an air inlet, and an air outlet; A one-way exhaust control valve, which is supported by a support frame and fixed inside the hollow body, the exhaust control valve is used to allow exhaust gas to be discharged through the exhaust port; a compression spring, the compression spring Is fixed between the exhalation control valve and the closed end, the compression spring is used to maintain a forward and reverse pressure, and is used to adjust the resistance against the airflow expelled by the patient; and an adjustment device, the An adjusting device is fixed on the closed end of the hollow body. The adjusting device is used to adjust the compression of the compression spring. The adjusting device includes a sliding piston which is movable inside the hollow body. The piston provides a A first abutting surface provides the compression spring, and the support frame provides a second abutting surface to the compression spring. 2 2. The device as described in item 21 of the scope of patent application, wherein an adjustable cam lever is fixed on the sliding piston to adjust the resistance against an exhaust air flow. 2 3. The device as described in item 22 of the scope of patent application, wherein the cam lever is adjustable to maintain a positive and negative pressure between 5 and 10 cm of water column height. 5KEATY200201TW.ptd Page 23 537911 6. Scope of Patent Application Scope. 24. The device according to item 21 of the scope of patent application, wherein the hollow body system is coupled with a sprayer, and the connection between the hollow body and the sprayer is used for the hollow body and the sprayer. A fluid transfer tube is established between the devices to deliver the drug to the patient's respiratory tract. 25. The device according to item 24 of the scope of patent application, wherein the open end of the hollow body is fixed to the sprayer in a detachable manner. 5KEATY200201TW.ptd Page 24