五、創作說明(/ ) 本發明係為-種短暫誘發耳聲傳射信_ 尤指-種具高分辨性之耳訊價測方法。法’ 目前,根據研究報告指出,因人 微弱聲音信號’可在外耳處利用高靈敏 :=:ΓΓ號),且此耳聲傳射和 來判斷==可:藉由分析耳聲_- 其原理係由於該耳蜗特殊構造的影響,使得 位的毛細胞對刺激頻率有選擇性,。 聲軸激,而一 声史傳:十二 的刺激頻率則愈來愈低。而耳蜗反應耳 2傳射W之主要毛細胞為外毛細胞,因外毛 的交化而改變長度,故對於聲波傳導至耳蜗内時的行進波 興=ellng wave)形態有加強振動的效果,進而增加聽 ^以度及解的藝性,即外毛細胞和聽力具高度相 關性。是故,能反應外毛細胞狀態之耳聲傳射信號和聽力 正常與否具有高度相關性。 短暫誘發耳聲傳射信號(transientiy 〇跟 oae ) iT'在給予人耳一短暫的聲音刺激後,在外耳道以麥 克八1劂到的回饋#號,其量測波形圖係如第三圖示。藉 由里測及分析耳聲傳射信號,吾人可以判斷聲波從耳道傳. 到耳螞刺激外毛細胞的途經是否有問題,以及外毛細胞的 功能是否正常。 492264V. Creative Instructions (/) The present invention is a short-term evoked otoacoustic transmission signal, especially a high-resolution ear hearing price measurement method. At present, according to a research report, due to the weak sound signal of a person, 'high sensitivity can be used in the external ear: =: ΓΓ number), and the otoacoustic transmission sum can be judged == possible: by analyzing ear sounds _- its The principle is that due to the special structure of the cochlea, the hair cells in place are selective to the frequency of stimulation. The sound axis is stimulated, and the history of a sound: the stimulation frequency of twelve is getting lower and lower. The cochlea responds that the main hair cells transmitting W in the ear 2 are outer hair cells, which change length due to the crossover of the outer hair, so it has the effect of strengthening vibration when the sound waves are transmitted into the cochlea. Furthermore, the artistic quality of hearing and understanding is increased, that is, outer hair cells and hearing are highly correlated. Therefore, the ear sound transmission signal, which can reflect the status of outer hair cells, is highly correlated with normal hearing. After transiently evoking otoacoustic transmission signals (transientiy 〇 and oae), iT 'gives the human ear a short sound stimulus, and the feedback ## in the external auditory canal is Mike Ba 1. The measurement waveform is shown in the third figure. . By measuring and analyzing the otoacoustic transmission signals, we can judge whether the sound waves are transmitted from the ear canal to the ears to stimulate the outer hair cells and whether the function of the outer hair cells is normal. 492264
五、創作說明(/) 而上述方式雖可判斷該耳蜗動作是否正常,但因反射 信號距離耳堝之位置較遠,又加上人體、環境噪音等因 素,而使此一反射信號中挾雜許多雜訊,所以麥克風接收 回來的45虎係包含二種主要成分,一為真正的耳聲傳射信 號,二為環境和人體的噪音,三為刺激信號打到耳道和鼓 膜等所反射回來的信號;故該耳聲傳射信號之信號/雜訊比 將會相對地降低,即檢測聽力之準確性亦相對降低。 然而,在目前市面上之掏取系統中,為了分離出真正 之耳聲傳射信號所使用之方法如下所述·· 因該短暫誘發耳聲傳射信號的信號強度和刺激強度成 非線性關係,且有隨刺激強度增強而漸趨飽和 (saturation,即刺激強度大幅增強但耳聲傳射信號的強 度只非常小幅增加)的趨勢。若於外耳發出—組刺激訊號 Η、+1、+1、-31 ( I為刺激強度)至内耳中,由耳内反射 出一組回傳信:虎(R1、R2、R3、R4),其中各回傳信號Rl 巴g真正的耳聲傳射^號E丨和刺激信號打到耳道和鼓膜等 所反射回來的信號Ll (Ri=Ei+u,ι = Η),而耳聲傳射信 唬Ει又可以分解為和刺激強度呈線性關係的部分 (EU),和非線性關係的部分(ENU),故將各反射信號 R卜R4相加後,因為耳道、鼓膜等的反射信號^和刺激強 度成線性關係’前三個刺激打到耳道、鼓膜等的反射信號 (LI L2 L3 )的和會跟第四個刺激打到耳道、鼓膜等的 反射信號(L4),強度相同但正負机反(因為L1:L2=L3二-L4 3)故使4耳道及鼓膜等反射信號會被抵消,又,V. Creation instructions (/) Although the above method can determine whether the cochlea is normal, but the reflected signal is far away from the ear pot, and the factors such as human body and environmental noise make the reflected signal mixed. There is a lot of noise, so the 45 Tiger series received by the microphone contains two main components, one is the true otoacoustic transmission signal, the other is the environment and human noise, and the third is the stimulus signal hitting the ear canal and the eardrum. The signal / noise ratio of the otoacoustic transmission signal will be relatively reduced, that is, the accuracy of detecting hearing is also relatively reduced. However, in the current extraction systems on the market, the method used to isolate the true otoacoustic transmission signal is as follows. Because the signal intensity and the stimulus intensity of the transiently induced otoacoustic transmission signal have a non-linear relationship. And there is a tendency to become saturated with the enhancement of the stimulation intensity (saturation, that is, the intensity of the stimulation is greatly increased but the intensity of the otoacoustic transmission signal is only increased very slightly). If it is sent from the outer ear — a group of stimulation signals Η, +1, +1, -31 (I is the intensity of the stimulus) into the inner ear, a set of postback messages is reflected from the ear: tiger (R1, R2, R3, R4), Each of the returned signals Rl and g is the true otoacoustic emission ^^ E 丨 and the stimulus signal hits the reflected signal Ll (Ri = Ei + u, ι = Η), and the otoacoustic transmission The radio signal can be decomposed into a linear relationship (EU) and a non-linear relationship (ENU) with the stimulus intensity. Therefore, after the reflection signals R and R4 are added, the reflection of the ear canal, eardrum, etc. The signal ^ is linearly related to the intensity of the stimulus. 'The sum of the reflection signals (LI L2 L3) of the first three stimuli hitting the ear canal, eardrum, etc. will be the same as the reflection signals (L4) of the fourth stimulus hitting the ear canal, eardrum, etc. The intensity is the same but the positive and negative machines are reversed (because L1: L2 = L3 二 -L4 3), so that the reflection signals of the 4 ear canals and eardrum will be canceled.
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經 濟 部 智 慧 財 產 局 員 工 消 費 合 作 社 印 製Printed by the Consumer Goods Corporation of the Intellectual Property Agency of the Ministry of Economic Affairs
五、創作說明(多) 射信號中和刺激強度呈線性關係的部分(E⑴亦 除,只留下非線性關係的部分 線性部分具飽和的特 U ^非 福;由是可知,將、έ⑽^使得觀视2视‘ χ & 將一組四個刺激所得到的四個回傳俨沪 相加後結果等於2Χ飢⑷X順或2Χ狐3,即耳聲; =刺激強度呈非線性關係部分的兩倍,再將所得 ==二即可得到真正的短暫誘發耳聲傳射信號 ,強产1 (以下稱為單組平均),但由於此一訊 = 故較長日㈣連續送出多_激信號, 斤有、且所仔到之單組平均的平均值(稱為信號平均 法),才能提高信號/雜訊比。但是基於市面上摘取系統所 使用之方法所得到之單組平均其信號/雜訊比較低,故對於 擷取耳聲傳射訊號之方法仍有改善空間。 為此’本發明之主要創作目的係提供一種提高單組平 均之信號/雜訊比,以期於短暫時間内擷取較高信號/雜訊 比之短暫誘發耳聲傳射信號之方法,。 為達上述目的所使用之主要技術手段係令實施此方法 之步驟係如下述·· 傳送一組刺激信號,即由外耳處輸入多數個聲音刺激 信號予内耳之耳蝸部; 擷取回傳信號,上述刺激信號送入耳内後,於外耳擷 取該耳内依序反射之一組回傳信號; 平均該組回傳信號中個別信號之前段部份,以送出個 別刺激後之一固定時間點作為區分所擷取個別回傳信號之 C7 D7 五、創作說明(多) 前段和後段,將整組傳 後除以-參數,所得號前段^^ 份; 虎即為本方法之單組平均之前段部 平均部份該組回傳信號之後段部份 號中除最後一個回傳俨辨 、^、、,回傳“ 相加後除以-參數;”二其:個別回傳信號後段部份 段部份; 斤“唬即為本方法之單組平均之後 的方:述雜訊比之短暫誘發耳聲傳射信號 面D之耳聲傳射信號’於-固定時間點前等同 ;因為:::統所 因:士刀析研究之發現’耳道、鼓膜反射信號之強 度於一固疋時間内將會趨近為零,故本方法於該時間點後 只取-組回傳㈣中前三個回傳信號將其相加並平均之, 來所操取k 5虎之後段將為最完整之短暫誘發耳聲 線 傳射信號(線性+非線性),故此方法可有效地提高短暫誘 發耳聲傳射信號之強度,以增加聽力檢測之準確性。 經濟部智慧財產局員工消費合作社印製 為使貝審查委員能進一步瞭解本發明具體之設計及 其他目的’茲㈤以圖式詳細說明如後: (一) 圖式部份: 第一圖:係本發明之一實際操作流程圖。 第二圖:係本發明之一實際操作示意圖,其揭示耳朵使用 該檢測之剖面圖。 第三圖··係本發明之一分析曲線圖。 (二) 圖號部份: 本紙張尺度適用中國國豕標準(CNS)A4規格(210 X 297公爱) C7 C7 經濟部智慧財產局員工消費合作社印製 五、創作說明((^) :;〇)外耳 (11) 2 ) 1耳卜 (2 0)麥克風 佳 月乡閱第圖及第二圖所示,係、為本發明之-較 佳貫施例,其步驟係包含有: 專^、’且刺激仏#b,即外耳(1 ◦)於不同時間點送 ::/T;信號(11、12、")予内耳(⑴之耳 馬心其中可三個刺激信號^…強度⑴相 冋’而第四個刺激信號係、為負三倍強度㈠ΧΙ); 操取回傳信號,上述刺激信號送人該耳蜗後,設於外 耳處的麥克風(2G).所接收回傳信號係4 R1⑴、 ⑴,、R3⑴、R4⑴,其中擷取時間t為G〜2G微秒; 平均該組回傳信號中個別信號之前段部份,以送出個 =激後之-固㈣間點作為區分所擷取個別回傳信號之 =和後段’再分別將整組回傳信號中之個別信號前段部 :二加後除以2 ’所得信號即為本方法之單組平均之前段 部份’其中經研究統計發現取決該固定時間點需大於6微 秒,於本實施例中該固定時間點係為8微秒; ;平均部份該組回傳信號中個別信號之後段部份,即將 ,組回傳㈣中除最後—個回傳信號外之其餘個別回傳信 號之後段部份相加後除以3,所得㈣即為本方法之單^ 平均之後段部份; 上述方法係依據研究報告指出在刺激信號送出經過δ 微秒後’耳道、鼓膜之反射信號會近乎消失,故整组回傳 信號中之個別信號在8微秒前仍摻雜該耳道、鼓膜之反射 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公复 I —l· -------It---------^ i^w— (請先閱讀背面之注意事項再填寫本頁) 五、創作說明(y) Ίβ祝 回傳訊號之=㈣該耳道、鼓膜之反射信號,將擷取該 ρ 刖倣秒(t<8贴)訊號值的第四個傳 R4(t)與前三個回值户味Di/、 U得1口疲 Μ㈣ 傳虎R1⑴、R2⑴、R3⑴相加,並平 可:肖除耳道、鼓膜之反射信號,亦可同時取 亍丑 耳專射化遽之非線性部份(ENL1); 士支膜:射::微秒(t>8贴)後因個別回傳信號將無耳道、 豉膜反射信號之摻雜,因此無 、 信號將第四個回傳HR :l、a膜之反射 P9“、 傳“號以(t)與丽三個回傳信號Rl(t)、 2’(、:3⑴相加, 可r到此-純敖暫耳聲傳射信號中之線性部份將不會消除,故 于1凡正之紐暫誘發耳聲傳射信號(EL1+ENL1)。 暫誘之:;:發::_知技術擷取短 W 較圖,其中,將-組刺激所得- 、、回傳之母個別信號分成兩部份,本方法求取單組 (Subaverage)之前、後部份之公式係為: 二V. Creation instructions (multiple) The part of the radio signal that has a linear relationship with the stimulus intensity (E⑴ is also divided, leaving only a part of the non-linear relationship with a linear part with a saturated characteristic U ^ Not blessed; it can be seen that, This makes the observation 2 vision 'χ & add four backhauls obtained from a group of four stimuli, and the result is equal to 2 × hunger X cis or 2 × fox 3, that is, ear sound; = part of the stimulus intensity has a non-linear relationship Twice the value, and then get == 2 to get a real short-term evoked otoacoustic transmission signal, a strong yield of 1 (hereinafter referred to as a single group average), but because of this news =, long sundial continuously sends more _ The signal / noise ratio can only be increased by the average value of the single-group average (referred to as the signal averaging method). However, the single-group average obtained based on the methods used in the market extraction system Its signal / noise is relatively low, so there is still room for improvement in the method of capturing otoacoustic transmission signals. To this end, the main purpose of the present invention is to provide a signal / noise ratio that increases the average of a single group, in the hope of short-term Short time to capture higher signal / noise ratio The method of transmitting signals through the ear. The main technical means used to achieve the above purpose is to implement the steps of the method as follows: Send a set of stimulus signals, that is, input a plurality of sound stimulation signals to the inner ear from the outer ear The cochlear part of the cochlea; after the stimulus signal is sent to the ear, a group of the return signals in the ear is sequentially reflected in the ear; the average part of the individual signals in the group of return signals is Send a fixed time point after the individual stimulus as the C7 D7 to distinguish the individual return signals captured. V. Creation instructions (multiple). For the front and back sections, divide the whole group by the -parameter, and get the number ^^ before the number. That is, the average part of the previous section of this method is the average part of the back part of the method. The last part of the back part number of the group is divided by the last return. Identify, ^ ,,, and return "divide by-parameter after addition;" It: the back part of the individual return signal, part after part; the “bluff” is the method after the single group average of the method: the noise ratio is briefly induced by the otoacoustic transmission signal surface D of the otoacoustic transmission signal 'in -Equivalent before a fixed point in time; ::: The reason for the study: the discovery of the Shidao analysis' the intensity of the ear canal and eardrum reflection signals will approach zero in a fixed period of time, so this method only takes-group back pass The first three return signals in the middle are added up and averaged, so the next section of k 5 tiger will be the most complete transient evoked otoacoustic transmission signal (linear + non-linear), so this method can effectively improve The intensity of the otoacoustic transmission signal is briefly induced to increase the accuracy of hearing detection. Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs to enable the panel reviewer to further understand the specific design and other purposes of the present invention. The detailed description is as follows: (1) Schematic part: The first figure: a flowchart of an actual operation of the present invention. The second diagram: a schematic diagram of an actual operation of the present invention, which discloses a cross-sectional view of the ear using the test. The third diagram is an analysis curve diagram of the present invention. (2) Part of drawing number: This paper size is applicable to China National Standard (CNS) A4 specification (210 X 297 public love) C7 C7 Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 5. Creative Instructions ((^):; 〇) outer ear (11) 2) 1 ear Bu (2 0) microphone Jiayue Township, as shown in Figure 2 and Figure 2, is a preferred embodiment of the present invention, the steps include: , ', Stimulus 仏 # b , that is, the outer ear (1 ◦) is sent at different time points :: / T; signal (11,12, ") to the inner ear (the ear of the horse's heart can have three stimulation signals ^… intensity "Phase phase" and the fourth stimulus signal is negative triple intensity (XΙ); the return signal is obtained, after the stimulus signal is sent to the cochlea, the microphone (2G) located in the outer ear. The received return signal It is 4 R1⑴, ⑴ ,, R3⑴, R4⑴, where the acquisition time t is G ~ 2G microseconds; the average part of the individual signals in the set of return signals is sent as the point after the excitation-the time between the solid points Differentiate the = and the back segment of the captured individual return signal, and then separate the front part of the individual signals in the entire group of return signals: add two and divide by 2 ' The average part of the previous paragraph of this method is' in which the research found that it depends on the fixed time point to be greater than 6 microseconds. In this embodiment, the fixed time point is 8 microseconds; the average part of the group returns The latter part of the individual signals in the transmission signal, that is, the remaining part of the individual return signals in the group return transmission except the last-the return signal is added up and divided by 3, and the resulting frame is the single method of the method. ^ Averaged the latter part; the above method is based on the research report that the reflected signals of the ear canal and eardrum will almost disappear after δ microseconds after the stimulus signal is sent, so the individual signals in the whole group of return signals are 8 microseconds before The reflection of the ear canal and tympanum is still doped. The size of this paper is applicable to China National Standard (CNS) A4 (210 X 297 public compound I —l · ------- It --------- ^ i ^ w— (Please read the precautions on the back before filling this page) 5. Creation Instructions (y) Ίβ wishes the return signal = 反射 The reflected signal of the ear canal and eardrum, will capture the ρ 刖 imitation seconds ( t < 8)) The fourth pass value R4 (t) of the signal value and the first three return values are the taste of Di /, U get 1 mouth fatigue. 1⑴, R2⑴, R3⑴ are added, and can be flat: In addition to the reflected signals of the ear canal and eardrum, you can also take the non-linear part of the ugly ears (ENL1); After 2 seconds (t > 8 stickers), due to the individual return signal, no ear canal or diaphragm reflection signal is doped, so no, signal will return the fourth HR: l, reflection of the a film P9 ", pass" number Add (t) to the three return signals Rl (t), 2 '(,: 3⑴), so r can go here-the linear part of the pure Ao acoustic transmission signal will not be eliminated, so 1 Fanzhengzhi temporarily induces otoacoustic transmission signals (EL1 + ENL1). Temporarily induce ::: 发 :: _ Knowledge technology to capture short W comparison chart, in which the individual signals of the-group stimulus-, and the returning mother are divided into two parts. Before this method obtains a single group (Subaverage) The formula of the latter part is:
Subaverage{t) = J ^1 ^ + ^ ^ + ^ (0 + (〇]/ 2 t < Sms lL^i(0 + i?2(〇 + i?3(/)]/3 8<t< 20ms 由上可知,本發明可有效地排除其他雜訊之干擾 而於同樣時間内取得較高耳聲傳射信號之信號/雜訊:匕 以統計理論說明,兩種方法所擷取到的短暫誘發耳 信號’就單組平均切8微秒的部份㈣,若吾 二呈非線性關係部份,現今方法將= ''始回傳信號相加除以2’在假設環境雜強度為N,信 度為s,統計上證明經由四個信號相加除以2所得^ D7 五 創作說明 ::二:為Ν’信號強度仍為s;而利用新方法將前三個刺 變成。之=回傳信號相加除“ 3所得到之雜訊強度會 方本担度仍為s ’ ’就信號/雜訊比來看,新方法 較 提昇了 ^倍(通常換算4 4.8dB)。若再考旦作 號的線性部份,新方法於成功地保留了單 秒後的,份,由是可知,本發明可確實於;二:Subaverage (t) = J ^ 1 ^ + ^ ^ + ^ (0 + (〇) / 2 t < Sms lL ^ i (0 + i? 2 (〇 + i? 3 (/)) / 3 8 < t & lt 20ms It can be seen from the above that the present invention can effectively eliminate the interference of other noises and obtain a higher signal / noise of the otoacoustic transmission signal in the same time: using statistical theory to explain that the two methods capture the The transient evoked ear signal is a portion of an average cut of 8 microseconds. If the second part is a non-linear relationship, the current method will add = '' the initial return signal and divide by 2 ''. N, the reliability is s, and it is statistically proved that the four signals are added and divided by 2 ^ D7 Five creation instructions: 2: Second: for N ′ the signal strength is still s; and the new three methods are used to change the first three spines. = The noise intensity obtained by adding back the divided signals will be equal to s'. In terms of signal / noise ratio, the new method is improved by ^ times (usually converted to 4 4.8dB). If Considering the linear part of the number once again, the new method successfully retains the copy after a single second. From this, it can be seen that the present invention can be used for certain;
取传k佳信號品質之短暫誘發耳聲傳射信號,故可 南为析聽力正常與否之準確性。 為此,本發明己確實增進產業上之利用性,並符合 =發明之新穎性、進步性等專利要件’爰法依具文提:申 經濟部智慧財產局員工消費合作社印製Taking the short-evoked otoacoustic transmission signal of the good signal quality of k, therefore, the accuracy of hearing is normal or not. To this end, the present invention has indeed improved the industrial applicability and conforms to the patent elements such as the novelty and advancement of the invention ’, according to the article: Application for printing by the Intellectual Property Bureau of the Ministry of Economic Affairs’ Consumer Consumption Cooperative
本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐)This paper size applies to China National Standard (CNS) A4 (210 X 297 mm)