TW446561B - Improved stabilization of prostaglandin drug - Google Patents

Improved stabilization of prostaglandin drug Download PDF


Publication number
TW446561B TW86109178A TW86109178A TW446561B TW 446561 B TW446561 B TW 446561B TW 86109178 A TW86109178 A TW 86109178A TW 86109178 A TW86109178 A TW 86109178A TW 446561 B TW446561 B TW 446561B
Prior art keywords
prostaglandin drug
Prior art date
Application number
Cheng-Gung Chen
Rung-Je Tsai
Huei-Ying Lin
Shu-Bin Liu
Original Assignee
Dev Center Biotechnology
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Application filed by Dev Center Biotechnology filed Critical Dev Center Biotechnology
Priority to TW86109178A priority Critical patent/TW446561B/en
Application granted granted Critical
Publication of TW446561B publication Critical patent/TW446561B/en



The present invention relates to a stable solid type prostaglandin drug, particularly a Misoprostol (± methyl 7-[3(Α)-hydroxy-2-β-(4(RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-oxycyclopenta-1Α-yl]heptanoate, which comprises an ammonio methacrylate copolymer. The ammonio methacrylate copolymer used in the stable solid type of the present invention comprises Eudragit RS series copolymers, Eudragit RL series copolymers, Eudragit S, Eudragit L, and a mixture thereof.
TW86109178A 1997-06-30 1997-06-30 Improved stabilization of prostaglandin drug TW446561B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW86109178A TW446561B (en) 1997-06-30 1997-06-30 Improved stabilization of prostaglandin drug

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TW86109178A TW446561B (en) 1997-06-30 1997-06-30 Improved stabilization of prostaglandin drug
JP23496697A JPH1135488A (en) 1997-06-30 1997-08-29 Prostaglandin agent improved in stability

Publications (1)

Publication Number Publication Date
TW446561B true TW446561B (en) 2001-07-21



Family Applications (1)

Application Number Title Priority Date Filing Date
TW86109178A TW446561B (en) 1997-06-30 1997-06-30 Improved stabilization of prostaglandin drug

Country Status (2)

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JP (1) JPH1135488A (en)
TW (1) TW446561B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0417401D0 (en) * 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
US8481565B2 (en) * 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug

Also Published As

Publication number Publication date
JPH1135488A (en) 1999-02-09

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