TW427916B - Process for providing a stable form of a fine-grained inhalation pharmaceutical composition and fine-grained inhalation pharmaceutical composition - Google Patents

Process for providing a stable form of a fine-grained inhalation pharmaceutical composition and fine-grained inhalation pharmaceutical composition

Info

Publication number
TW427916B
TW427916B TW083107152A TW83107152A TW427916B TW 427916 B TW427916 B TW 427916B TW 083107152 A TW083107152 A TW 083107152A TW 83107152 A TW83107152 A TW 83107152A TW 427916 B TW427916 B TW 427916B
Authority
TW
Taiwan
Prior art keywords
substance
grained
fine
pharmaceutical composition
mixture
Prior art date
Application number
TW083107152A
Other languages
Chinese (zh)
Inventor
Eva Ann-Christin Trofast
Lars Erik Briggner
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA945675A external-priority patent/ZA945675B/en
Application filed by Astra Ab filed Critical Astra Ab
Application granted granted Critical
Publication of TW427916B publication Critical patent/TW427916B/en

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Abstract

The present invention relates to a process for providing a stable crystallinic form to a fine-grained substance or a substance mixture, which can be produced, stored and used while maintaining the aerodynamic properties required for inhalation of such a substance or a substance mixture, by (a) in case of a substance mixture, preparing a homogenous mixture of the substances; (b) micronizing, direct precipitating or diminishing by any conventional method the substance or substance mixture into a particle size required for inhalation, the particle size being less than 10 mu m; (c) optionally preparing a homogenous mixture of the desired substances when each substance has been introduced from stage (b) as separate fine-grained particles; (d) conditioning said substance or substance mixture by treatment with a water containing vapor phase in a controlled fashion; and (e) drying.
TW083107152A 1994-07-29 1994-08-04 Process for providing a stable form of a fine-grained inhalation pharmaceutical composition and fine-grained inhalation pharmaceutical composition TW427916B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA945675A ZA945675B (en) 1993-08-27 1994-07-29 Process for conditioning substances
PH48732A PH31549A (en) 1993-08-27 1994-08-02 Micro formoterol particles.

Publications (1)

Publication Number Publication Date
TW427916B true TW427916B (en) 2001-04-01

Family

ID=26652402

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083107152A TW427916B (en) 1994-07-29 1994-08-04 Process for providing a stable form of a fine-grained inhalation pharmaceutical composition and fine-grained inhalation pharmaceutical composition

Country Status (1)

Country Link
TW (1) TW427916B (en)

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Legal Events

Date Code Title Description
GD4A Issue of patent certificate for granted invention patent
MK4A Expiration of patent term of an invention patent