TW403724B - Method and composition for inhibiting growth of microorganisms including peracetic acid and a non-oxidizing biocide - Google Patents

Abstract

The present invention provides a composition and method of administering same for inhibiting the growth of microorganisms. The composition of the present invention includes sufficient amounts of a peracetic acid and a non-oxidizing biocide. The method of the present invention includes the step of adding sufficient amounts of the peracetic acid and the non-oxidizing biocide to industrial process waters.

Description

Α7 B? Ppm of agent.

Qa / QA + Qb / QB = Cooperative effect index QaQb < 1, for synergy, for addition effect > 1, for antagonism The following test method was used in the experiment of the invention. Obtained process water from several paper mills for testing. Peracetic acid (5% active material, obtained from FMC) at the indicated tear level was added to the portion of water obtained from each paper mill. After 30 minutes of contact, add the specified concentration of non-oxidizing biocide to the portion of water to which peracetic acid has been added, mix well and place in an orbital shaker at 37 ° C. At each specified contact time, a portion of each water was sampled and measured to determine the total number of viable organisms expressed in colony forming units (CFU / mL) per milliliter on a tryptic glucose extract (TGE) agar. Then select the end point of the reduction of viable organisms with 2, 3, 4, or 5 log 10 to calculate the synergy. 403724 r: · r. 'A7 _B7___ V. Description of the invention (1) Generally speaking, the present invention relates to the control of biological growth. In more detail, the present invention is that η inhibits the growth of tritium organisms in industrial water. The presence of aquatic organisms in water, especially in industrial water, is a never-ending concern for industrial producers. Examples of industrial water used in which biological organisms can interfere with industrial processes include: cooling tower water; mining process water; food processing water: sugar in processing water, and the like. In the cracked paper industry, the growth of pulp and paper mill water removal organisms can adversely affect the final paper product. The life of a derelict depends on a particular system of food, sickle, and temperature. The degree of panning of papermaking machinery and the rolling of sulfide-containing hydrate compounds and cracking materials provide ideal growth conditions for a variety of microorganisms. Some contaminated organisms can cause damage to pulp, ingredients or chemical additives.撖 Organisms can cause sediments that fall apart and fall into the pulp ingredients * resulting in loss of product / and / or defects such as holes or spots in the final product. The end product is unstable paper or lower value paper. Robertson's use of the younger brother Β skimming method ft »The usfl of phase-nontrast icroscopy to assess and differentiate the πrob ia 1 population of a paper Bill, TAPPI Journal, 83 < , P. (March 1993). The presence of tritium organisms in industrial water systems has resulted in the formation of biological deposits on industrial machinery. These deposits cause: erosion; rupture; increased settling time; reduced yield; high chemical costs; Austrian flavor; and expensive deposit control schemes. In the paper mill, ruptures, blockages, and pumping of about 70Z were reported due to sticky sediment. Saf ade, Tackling the S 1 i ae Prob 1 < > in Paper Mill. This paper size applies the Chinese National Standard (CNS) A4 specification (210X297 mm): --- ΠΊ,-i In— wood | Order 11111 (please read the note $ on the back before filling this page) · "Printed by the Central Standards Bureau of the Ministry of Economic Affairs, printed by the shellfish consumer cooperative, printed by the Central Standards Bureau of the Ministry of Economic Affairs, printed by the employee consumer cooperatives 403724 ..., V. Description of the Invention (2)), PTI, p. 280 (September 1988). Adhesives can be defined as "adhesives or aggregates * caused by organisms that are mixed in various proportions of pulp, fillers, soil and other substances, and have different physical properties and a continuously changing rate. "In most industrial treatment waters, especially pulp and paper mill systems, spore-forming bacteria and ruminants cause slime formation. The latter is most common in paper-making adhesives. Hui bacteria also cause the formation of slime. The traditional method of controlling the growth of aquatic organisms is through the use of biocides. Biocidal_ generally can be divided into two categories: oxidized; and non-oxidized. Some of these biocides act on withdrawal in one of three ways: attacking the cell wall; the cell membrane; or the cell composition. Although biocides can control the growth of organisms, economic and environmental considerations require more advanced methods. One problem with the use of biocides is that noble and expensive chemicals M are required to control the growth of the organism. To date, no commercial biocide has a long-term biocidal effect. The effect is rapidly diminished by exposure to physical conditions such as temperature and the combination of constituents contained in the system that have an affinity for it *. This result is limited to |! 1 and its biocidal effect is eliminated. Therefore, the use of such biocidal products involves continuous or frequent additions in the papermaking system. Furthermore, these additions must be made in multiple points or plaques in the system. The cost of the biocide box and labor costs are significant. In addition, the amount of this type of chemical is very toxic in order to effectively control the withdrawal of organisms. As a result, environmental regulations limit the amount of biocide that can be safely discharged into the environment. This paper size is applicable to China National Standard (CNS) 8-4 specifications (210 X 297 mm)-^-5 ---- ^ ------ Order (Please read the precautions on the back before filling this page ) · -5, A7 B7 403724 V. Description of the Invention (3) Therefore, an improved method M is needed to control the growth of aquatic organisms in industrial process water. (Please read the precautions on the back before filling out this page.) According to the present invention, the growth of microorganisms can be inhibited without using a special biocide that is placed high. The present invention provides a composition for controlling the growth of aquatic organisms in industrial process water. The composition includes a family of acetic acid and a non-oxidizing biocide. The composition of the present invention has unanticipated synergistic activity against tadpole-resistant organisms, including bacteria and emblems. Acetic acid is an organic biocide. It was previously used only in food products at a concentration of 0.1-U. The present invention also provides a method for controlling the growth of tadpole organisms in the water for race treatment. Some of the process water is preferably filled from pulp and paper mill cracking process water, industrial cooling water and mining water. The steps of the method include adding peracetic acid (PAA) and non-oxidizing biocide to the water. The combination of peracetic acid (PAA) and non-oxidizing biocides was found to enhance the efficacy of non-oxidizing biocides. Printed by the Consumer Cooperatives of the Central Bureau of Quasi-Economic Bureau of the Ministry of Economic Affairs. In one embodiment of the present invention, the biocide is selected from the group consisting of: isosleepazoline; glutaraldehyde; DBNPA; Quaternary ammonium compounds; 4,5-digas-1,2-dithioketone; and 4,5-dichloro-2-N-octyl-4-isosleepazoline-3-fluorene, decyl Thioethylamine, pro-peptide, 2-bromo-2-nitropropane-1,3-diol, 4,5-dichloro-1,2-dithiocarbamidine, dodecyl argon Gadolinium acid, 1- (3-chloroallyl) -3,5,7-triazine-piridiamantine gaseous, dibromodicyanobutane and bis (trichloromethyl) ®. In one embodiment, peracetic acid is first added to the biocide in the water system. The lean-adhesive system of the present invention provides an increased composition for inhibiting the growth of abiotic organisms. Another advantage of the present invention is to provide inhibition of the growth of organisms. The paper size is applicable to the Chinese National Standard (CNS) A4 specification (210X 297 mm) 6 403724% at ------- B7__ 5. Description of the invention (4) An enhanced method. Furthermore, the one advantage of the present invention is that it reduces the amount of expensive chemicals that are inhibited by the growth inhibition. «By adding peracetic acid to the water system, the non-oxidizing biocide is effective at low temperature, and the effect of reducing the growth of organisms can be proved to be long-acting. This enhanced efficacy eliminates the need to repeatedly add biocidal to the papermaking system. Furthermore, one of the advantages of the present invention is to provide a more cost-effective and more user-friendly method for handling the removal of organisms. Other features and advantages of the present invention are described in the detailed description of the preferred embodiment, and can be more clearly understood from it. The present invention provides an improved composition for inhibiting the growth of tadpole organisms and a method for applying the composition to a tadpole system. The composition includes a sufficient amount of peracetic acid and non-oxidizing biocide. Printed by n · IT- —Ί I. *-衣 II-. ---- 11 f.,. (Please read the notes on the back before filling this page) *-This The biocide composition of the invention includes a biocidal sheet that exhibits a synergistic effect when acetic acid and acetic acid are added to a roll. Examples of suitable biocides include: iso-fileline; methyl dithiocyanate; glutaraldehyde; DBNPA; carbamate; quaternary ammonium compounds; 4, < 5-diamine-1,2-di Thio-3-hydrazone; and 4,5-dihel-2-N-octyl-4-isosleepazole_-3_fluorene, decylthioethylamine, fluorenphthalaldehyde, 2-bromo-2 -Nitropropane-1,3-diase, 4.5-diaza-1,2-dithiopan-3-one, dodecaneguanidine chlorate, 1- (3-chloroallyl) -3 , 5,7-triaza-bumandamantane chloride, dibromodifluorenylbutane and bis (trichloromethyl). Of course, mixtures of these biocides can also be used. Biocides can be obtained from chemical suppliers, such as Auer i can. The paper size is applicable to Chinese National Standard (CNS) A4 (210 X 297 mm) 403724 ^ 'B7 V. Description of the invention (5)

Cyanaai d * Buck ^ an, Betz »Dearborn > Econoni cs Laboratory, Inc. > Merk * Nalco Cheeical Coipany» and Vine1 and Cheai ca1 〇 Biocides can also be obtained from the first supplier of chemical products. One of them is PMC Corporation in Philadelphia, Sev. The combination of non-oxidizing biocide with acetic acid and tritium provides an expected synergistic η system. The synergy η is a cooperative effect of the combined peracetic acid and non-gasified biocidal thin film, which produces a greater effect than the sum of the effects of the single use of peracetic acid and non-oxidized biocidal. The optimum amount of acetic acid and non-oxidizing biocide to be linked to the efficacy of the present invention depends on the type of Gonglai water being treated. In addition, the concentration of the combined constituents varies widely * and depends on conditions such as temperature and acid age of the water, and the number of salamanders. Concentrations can be as low as one part per million by weight (ρρ0 up to 250 PP ·. As for biocides, the upper and lower limits of the required concentration depend on the specific biocide or combination of biocides used. Economy Printed by the Ministry of Central Standards Bureau Consumer Cooperatives (please read the note f on the back before filling out this page) Further, the suitable biocides that can be used in the present invention are usually obtained at different usable concentrations (level of activity). The ratio varies depending on the specific biocide combined with peracetic acid. For example, the peracetic acid used in the following examples is 5% active, glutaraldehyde is 50% active, and DBNPA is 20% active. Therefore, a value of 1 The ratio of PAA: Glut of 1: 1 is 1:10 when the active substance is based, and the ratio of PAA: DBNPA of 1: 1 is 1: 4 when the active substance is based. The following are applicable to the present invention Biocides, including the active substance percentages of each biocide, are examples only and are not intended to be limiting: Isoprazole This paper is sized to the Chinese National Standard (CNS) A4 (210X297 mm) r. · R r. · r Shellfish consumer cooperation with the Central Bureau of Standards of the Ministry of Economic Affairs (6) Porphyrin (1.5 3: 8 ".); Glutaraldehyde (50: 1; &".); Dithio * acid formaldehyde (10 2 ai ·); DBNPA ( 20 ϋ; ai ·): carbamate (30:!: 3 ″.); Quaternary ammonium compound (31:!: 3.1.); 4,5-diaza-1,2-dithio-3 -Pyrene (5 Z ai); and 4,5-dichloro-2-N-octyl-4-isoI * oxazolin-3-one (2;!: Ai), where ai represents the active ingredient. The method of the invention can inhibit the growth of tadpole organisms in processing water. The steps of the method include adding the peracetic acid and non-oxidizing biocide of the present invention to the water. In one embodiment, the biocide and acetic acid It is a separate component added to the system. Peracetic acid can be added by any known method as long as it can be connected to the required concentration in the system. After the controlled addition of peracetic acid, the non-gasification is killed. Biology_ is added to the water system. In one embodiment, the non-oxidizing biocide is added to the system in thirty minutes of acetic acid. Like the addition of peracetic acid, as long as it can be added to the water system Concentration of pain, biocidal thin can be relied on It is known to add. In one embodiment, the method includes adding about 5 to 250 PP · of non-oxidizing biocide and about 10 to 250 ppb of acetic acid. In one embodiment, the biocide and peracetic acid are produced by about It exists in the range of about 1 to 100 ρρη. Peracetic acid is a unique oxidant, its use is different from other oxidants. The structure of the molecule is:

HaCOOOH The tail of this hydrazone compound allows PAA to penetrate bacterial cells. This allows the molecule to block the SS and S-Η bonds inside and outside the organism, and is more suitable than other oxidants. The paper size is in accordance with the Chinese National Standard (CNS) A4 specification (210 × 297 mm). (Fill in this page) Clothing · Order Printed by the Central Laboratories of the Ministry of Economy, Printed by Shellfish Consumer Cooperatives, A7 ^

403724 -_b7 _L V. Description of the invention (7) Faster and more effective sterilization. Other oxidants, such as H0C1, ClOi, Η · 0 », etc., do not penetrate cells in this way, because they do not have an organic part that can enter the ribs into thin cells. Peracetic acid can always be used separately from its concentration. Because it is an equilibrium molecule, it decomposes back to its starting product after dilution and it has never been expected to be active at low concentrations. However, its decomposition rate is much lower than expected, making it possible to provide unexpected synergistic effects with other biocides when used at low wolfness (down to 55: 10PP · or 0.5ρρ · active substance of the product). For many years a acetic acid has been used as an insecticide in food mash * but is generally used at higher concentrations (10,000 to 100,000 ?? 1). Until recently, peracetic acid has never been used in the paper industry to control the removal of water from papermaking machinery. Examples of the present invention will now be described, M being used as an example and not as a limitation. The following examples illustrate the known synergistic systems of the compositions of the present invention. Cooperative use is accepted by S. C. Kull et al.

Allied Mirrobiology, No. 9, pp. 538-541 (1961) < / shows mathematically. It is displayed as follows: The following applies to the present invention: QA = PP · which produces a single active non-oxidizing biocide with one endpoint. UB = PPB producing active peracetic acid with a single end. Producing a combination of end point and non-oxidizing biocide meets acetic acid ρρ · 〇ικ = producing a combination of end point and peracetic acid combined non-oxidizing biocide This paper is applicable to China National Standard (CNS) A4 specification 210X297 mm) (Please read the notes on the back before filling this page)

-10-ppm of Α7 B? Agent.

Qa / QA + Qb / QB = Cooperative effect index QaQb &lt; 1, for synergy, for addition effect &gt; 1, for antagonism The following test method was used in the experiment of the invention. Obtained process water from several paper mills for testing. Peracetic acid (5% active material, obtained from FMC) at the indicated tear level was added to the portion of water obtained from each paper mill. After 30 minutes of contact, add the specified concentration of non-oxidizing biocide to the portion of water to which peracetic acid has been added, mix well and place in an orbital shaker at 37 ° C. At each specified contact time, a portion of each water was sampled and measured to determine the total number of viable organisms expressed in colony forming units (CFU / mL) per milliliter on a tryptic glucose extract (TGE) agar. Then select the end point of the reduction of viable organisms with 2, 3, 4, or 5 log 10 to calculate the synergy. A7 B7-% a 4QS7 ^ d V. Description of the invention (9) 例 1 case shows the anti-microbial synergistic biocide (ppm product) of paper mill ingredients with a degree of 醸 _7.0 30 minutes 90 minutes 5 hours 24 hours PAA -10 2. 3x106 4. 0x106 2. 8x106 6.4x10® PAA-20 5. 8xl05 5. 3x105 2. 3x105 6. 5x105 _ • 0 minutes 60 minutes 4. 5 hours 24 hours Glut-50 3. 2x10® 3.2x104 <101 &lt; 10 丨 Glut-30 3.7x106 2. 5x105 &lt; 1〇 '&lt; 1〇' Glut-20 4.2x106 7.2x105 2. 6x104 1.ΙχΙΟ2 Glut-10 4. 4x106 2. 8x10® 2. 3x106 9. 5x102 Glut-10 / PAA-10 4. 5x10® 3. 2x105 5. 3χ104 1.9x102 Glut-10 / PAA-20 1_2χ105 5.3χ104 2. ΙχΙΟ4 3. ΙχΙΟ2 Control group-0 2. 3χ106 Ι. ΟχΙΟ5 3. 3χ106 5.ΟχΙΟ6 After receiving «in 90 minutes, the reduction of 21ogie is achieved by the following: Peracetic acid &gt; 20 ρρ · (40ρρ ·) Please read the note above and fill in the letter 写 Write this page to order the center of the Ministry of Economic Affairs Standard Bureau Shellfish Consumer Cooperative Co., Ltd. printed pentadienyl = 5〇ρρ · peracetic acid = 20ρρ · / glutericol = 10ρρ · Synergy Index (SI) = 10/50 + 20/40 = 0.7 After that, the reduction of 21og1D is as follows: in case of acetic acid> 20 ρρ · (40ρρβ) glutarol = 2〇ρρ · acetic acid = 10pp · / pentanexel = l〇ppn Synergy Index (SI) = 10 / 40 + 10/20 = 0.75 This paper size applies to China National Standard (CNS) A4 (210X297 mm) 12-

V. Description of the invention (10) After receiving «in 24 hours, the following will be 41ogl. Reduction of peracetic acid &gt; 20 ρρ · (40ρρ · &gt; glutaraldehyde = 20ρρ · case of acetic acid = 10ρρ · / glutaraldehyde = 1〇ρρ · synergy index (SU = 10/40 + 20/40 = 0.75 隹2 cases of biocide (ppm product) printed by the Shell Standard Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs 30 minutes 90 minutes 5 hours 24 hours PAA-5 7.4x105 8. 5x105 7. 8x105 8. 8x105, PAA-10 £ 6.4xl. 5 6. 7xl05 5 5.2x105 2.9x10® ίΡΑΑ-20-; 4. 0x105 5.4xl05 5 l.OxlO5 5. lxl05 0 minutes 60 minutes 4. 5 hours 24 hours DBNPA-100 3.9x105 &lt; l〇 '<101 &lt; 101 DBNPA-75 5. lxl〇5 &lt; 10 丨 &lt; 10 丨 &lt; 10 丨 DBNPA-50 6. OxlO5 8. lxl〇2 &lt; 1〇' &lt; 10 * DBNPA-25 6 OxlO5 3. 3x103 &lt; 1〇 '9. 4x104 DBNPA-100 / PAA-5 4.3xl〇5 &lt; l〇' &lt; 10 丨 &lt; 10 丨 DBNPA-75 / PAA-5 6. lxl〇5 &lt; l0 '&lt; 10 * &lt; 1〇' DBNPA-50 / PAA-5 3. 7x105 &lt; 10 丨 &lt; 1〇 '&lt; 1〇' DBNPA-25 / PAA-5 8. 8x105 3. 4χΓ 〇3 1. lxl〇Z &lt; 1〇 'DBNPA-100 / PAA-10 5.5xl〇5 &lt; l〇' &lt; 10 * <10 丨 DBNPA-75 / PAA-10 1.4xl〇5 &lt; 10l &lt; 10 ′ &lt; 1〇 'DBNPA-50 / PAA-10 9. 5xl〇4 &lt; 10 丨 &lt; 1〇 '&lt; 10 丨 DBNPA-25 / PAA-10 3. 6xl〇4 &lt; l〇' <10 丨 &lt; 10 丨 DBNPA-100 / PAA-20 2.OxlO5 &lt; l〇 '&lt; 1〇' &lt; 10 丨 DBNPA-75 / PAA-20 5.4xlO5 &lt; 10 丨 &lt; 10 丨 &lt; 10 丨 DBNPA-50 / PAA-20 4. 5x105 &lt; 10丨 &lt; 1〇 '&lt; 1〇' DBNPA-25 / PAA-20 3.7xl05 &lt; 10] &lt; 1〇 '&lt; 10 丨 control group-0 3. 7x105 9. OxlO5 3. OxlO5 2. 4xl〇6 This paper size applies Chinese National Standard (CNS) A4 specification (210X297mm) (Please read the precautions on the back before 'ipk page') Order 13-403724 A7 B7 V. Description of Invention (11) in 90 minutes After the contact, the following reduction of 5 Ugie meets acetic acid> 20 ρρ (40ρρ · &gt; DBNPA = 75pp · acetic acid = 5pp ^ / DBNPA = 5〇pp · Synergy Index (SI) = 5/40 + 50 /75=0.79 in case of acetic acid = 10pp ^ / DBNPA = 25pp · Synergy Index (sn = 10/40 + 25/75 = 0.58 After 24 hours of contact, the following values have been reduced to 51ο8ι »peracetic acid &gt; 20 ρρ · ( 40ρρ leg) DBNPA = 50pp · Meet Acetic Acid = 5pp ^ / DBNPA = 25pp · Synergy Index (SI &gt; = 5/40 + 25/50 = 0.625 ^ n * L--ill--I ** 1 ^ 1 · 1 (Please read the note on the back before filling in this page), τ Printed by the Consumers' Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs This paper is printed in accordance with Chinese National Standards (CNS) Α4 specifications (210X 297 mm) 14 A7 B7 __4 (13724 V. Description of the invention (12) F. S example shows the synergistic activity of anti-xie organisms in paper mill ingredients with acidity of 7.1 degrees °° The central government bureau of the Ministry of Economic Affairs staff consumer cooperatives printed biocide (ppm product) ) 30 minutes 2 hours 5 hours 24 hours PAA-25 2. 2x10® 1.4x10® 2.9x10® 7. 3x106 PAA-50 2. 9x10® 7. 5x104 2.lxlO4 1.8x10® PAA-100 6. 8x102 6. lxlO2 5.9xl〇2 2.4xl0 0 0 minutes 1.5 hours 4.5 5 hours 24 hours MBT-5 9. 8x10® 7. lxl6 6 1.6x10® MBT-10 3.6xl06 6 5.7xl06 6. 8xl〇6 MBT-25 2.4x106 8. 0x105 7. 5x106 MBT-50 2. 2x10® 2. lxlO6 2. lxlO5 3. 4xl〇5 PAA-10 / MBT-5 3. 8xl〇6 7. 7x106 4. 6xl〇7 PAA-10 / MBT-10 4. 3x106 5. 2x106. 5x10. PAA-10 / MBT-25 1.9x106. 6x10® 1. lx10O7 PAA-10 / MBT-50 3. 8x10® 1.7x10® 3. 4xl〇5 7. 7x104 PAA-20 / MBT-5 1.4x10® 2. lxl O6 1.8xl07 PAA-20 / MBT-10 1.9x10® 1. lxlO6 1.6xl07 PAA-20 / MBT-25 1. lxlO5 4. 6xl05 5. 3xl0G PAA-20 / MBT-50 1.7 x10® 6. 0x10 ^ 6.3xl04 4 2.4xl03 PAA-40 / MBT-5 8. 2xl〇4 2. 8xl〇4 1.2xl07 PAA-40 / MBT-10 9. 2xl〇4 2. 5xl 〇4 l_3xl07 PAA-40 / MBT-25 6. 3xl〇4 1. 6xl04 4xl05 PAA-40 / MBT-50 1.4xl05 4. 9xl04 4 2xl04 1.8xl03 control Group-0 1.lxl07 1.5xl07 3. lxlO7 7. 5xl03 After 24 hours of receiving «, the following was converted to 310S *. (Please read the precautions on the back before filling this page) The paper size applies the Chinese National Standard (CNS) A4 specification (210 × 297 mm) 15 -.1C- 403724 A7 B7 r. · V. Description of the invention (13) Acetic acid &gt; 100 PP · &lt; 200ρρ · &gt; MBT &gt; 5〇ρρ · (ΙΟΟρρ ·) peracetic acid = 20ρρ · / ΜΒΤ = 50ρρ · Synergy Index (SI &gt; = 20/200 + 50/100 = 0.6 in After 5 hours of contact, the following rapid reduction of 31ogie meets acetic acid &gt; 50 ρρ · ΜΒΤ &gt; 50ρρ · (IOOpp ·) Acetic acid = 20ρρ · / ΜΒΤ = 50ρρ · Synergy Index (SlH20 / 50 + 50/100 = 0.9 ( Please read the notes on the back before filling this page.) Order the paper printed by the Central Standards Bureau of the Ministry of Economic Affairs, the Consumers' Cooperatives. The paper size applies to the Chinese National Standard (CNS) M specification (210X 297 mm) 16 403724 A7 B7 V. Description of the invention (14) The 4th case of n * mm ϋ— _ printed by the Central Laboratories of the Ministry of Economic Affairs, Consumers Cooperatives, and a synergistic active biocide (ppm product) against 撖 organisms produced by a paper mill with a pH of 7.28 Minutes 2 hours 5 hours 24 hours PAA-25 1.3xl05 2_4xl05 5 1.8x10® 3. 〇χΙΟ7 PAA-50 1.6x103. 5χ103 1.0x104 1.7χ107 PAA-100 1.3x102 1.5x103 1.5x103 8. ΙχΙΟ6 W 0 minutes 1. 5 hours 4. 5 hours 24 hours CARB-50 9. 8x10® 1 ΙχΙΟ7 2. 6x10® CARB-100 9.4x10® 7. 2x106 7. 8x104 CARB-150 1. ΙχΙΟ6 Ι.ΟχΙΟ5 3. 8χ104 CARB-200 4. 7x106 1.8χ106 Ι.ΟχΙΟ5 3. 〇χΙΟ4 PAA-10 / CARB- 50 2. 8χ106 2. 5x10® 2. 8χ104 PAA-10 / CARB-100 3. 2x10® 5.0x104 4. ΟχΙΟ4 PAA-10 / CARB-150 3. 0x106 2. 6x104 4. 8x104 PAA-10 / CARB-200 2 · 2χ106 1 · 4χ105 5. 9x104 2. 5χ103 PAA-20 / CARB-50 1. ΙχΙΟ5 2. ΟχΙΟ6 2. ΙχΙΟ3 PAA-20 / CARB-100 3. 9x104 4. 5χ104 1.2χ103 PAA-20 / CARB-150 2. 3χ104 2. 5χ104 1.5x103 PAA-20 / CARB-200 3.7x105 2. 5x104 1. 9χ104 8. ΙχΙΟ2 PAA-40 / CARB-50 2. 3χ103 1.2χ103 9 · 3χ102 PAA-40 / CARB-100 2.0χ103 7. ΟχΙΟ2 5. 4χ102 PAA-40 / CARB-150 1.4 × 103 6. 6χ102 6.8χ102 PAA-40 / CARB-200 Ι.ΟχΙΟ4 1.3 × 103 5. 6χ102 6. 〇χΙΟ2 Control group-0 1.2x107. 3. 0x106 3. ΟχΙΟ6 3. 2χ107 After 2 hours of contact, the reduction of 21og1 () is achieved by the following: (Please read the precautions on the back to write this page)-. 、 1Τ This paper size applies to China National Standards (CNS) Α4 specifications ( (210 × 297 mm) 17 V. Invention IRA7? 4 A7 B7 u Case of acetic acid = 5〇ρρ · CARB> 200pp · (400ρρ ·) Case of acetic acid = 20pp ^ / CARB = 100pp · Synergy Index (SI) = 20/50 +100/400 = 0.65 in case of acetic acid = 40pp ^ / CARB &lt; 50pp · Synergy Index (SI &gt; = 40/50 + 25/400 = 0.8625) After 5 hours of contact, the following decrease in 41ogie is met: in case of acetic acid &gt; 100 PP · (200ρ · &gt; CARB &gt; 200pp · (400ρρ ·) meets acetic acid = 40pp «/ CARB = 100pp · Concordance Index (sn = 40/200 + 100/400 = 0.45 After 24 hours pick up *, M following 40% reduction of peracetic acid &gt; 100 ρρ · (200ρ ·) CARB &200; 400pp 丨 (400ρρ ·) &lt; &gt; Printed by the Staff Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs (Please read the precautions on the back before filling this page ) Acetic acid = 10pp »/ CARB = 200ppb Synergy Index (SI) = 10/200 + 200/400 = 0.55 Peracetic acid = 20pp ^ / CARB = 50pp · Synergy Index (SI &gt; = 20/20 0 + 50/400 = 0.225 in case of acetic acid = 40pp ^ / CARB = 50ppn This paper size applies to Chinese National Standard (CNS) A4 (210X297 mm) 18 1-03724 A7 弋 B7 Printed by the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs V. Explanation of the invention (16) Synergy Index (SI) = 40/200 + 50/400 = 0.325 5th biocide (ppm product) 30 minutes 2 hours 5 hours 24 hours PAA-25 4. 2x10® 2.4x10 ® 5. 3x106 1.7x107 PAA-50 4.4x104 1. lxlO5 7. 3x104 1.9x107 PAA-100 8. OxlO2 1. lxlO3 Ι.ΙχΙΟ3 1.3x107 0 minutes 2. 5 hours 4. 5 hours 24 hours QUAT-25 2.7x105 3. ΟχΙΟ5 1.8x107 QUAT-50 l.OxlO5 1.7χ105 Ι.ΙχΙΟ7 QUAT-100 7.9x104 8. 6χ104 5.2x10® QUAT-200 7. 5x104 6 · 4χ102 7. 2χ102 1.6χ10Z PAA-10 / QUAT-25 1.2xl 〇5 2. ΟχΙΟ5 1.7x107 PAA-10 / QUAT-50 6. 6x104 1.3x105 7.3x106 PAA-10 / QUAT-100 1.3x103 3. lxlO3 1.6x107 PAA-10 / QUAT-200 1.7x10s 5. ΟχΙΟ2 6 · 8χ102 2.9x106 PAA-20 / QUAT-25 1.8χ105 1.2x105 4. 9χ106 PAA-20 / QUAT-50 9. lxlO4 1.2χ105 6. 5χ106 PAA-20 / QUAT-100 3. 9χ ίΟ3 6. 8χ103 5. ΟχΙΟ6 PAA-20 / QUAT-200 6. 3x104, 5.4χ102, 6.6χ102 2.4χ102 PAA-40 / QUAT-25 3.4x103 4. 〇χΙΟ3 8. 9χ106 PAA-40 / QUAT-50 1.9x103 1_7χ103 3. 〇χΙΟ5 PAA-40 / QUAT-100 2. 〇χΙΟ3 1 · 7χ103 4. 〇χΙΟ5 PAA-40 / QUAT-200 1. · 3χ103 3. 7χ102 5.3x102 1.9χ102 Control group-0 1. lx107 0.7x107 1.3χ107 2 lxlO7 This paper size is in accordance with Chinese National Standard (CNS) A4 specification (210X297 mm) 19 403724 Α7 Β7 &lt; r ··· V. Description of the invention (17) After 24 hours of contact, the following has reached a reduction of 21ogie: Case of acetic acid> 100ρρ · (200ρρ · &gt; QUAT = 200pp · (400ρρ ·) Μ acetic acid = 40pp ^ / QUAT = 50pp · Synergy Index (SI) = 40/200 + 50/200 = 0.45 in 3 hours and 5 After hours of contact, the following reductions of 41ogl0 were achieved with acetic acid = 100ρρ · QUAT = 200pp · acetic acid = 40ppi / dUAT = 25pp · Synergy Index (SI &gt; = 40/100 + 25/200 = 0.525 1 --- *- · &Lt; —- *-1-1., clothing I. I '-*' (Please read the note on the back before filling in this page) Order printed by the Shellfish Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) 20 A7 B7 --4 ^ 3124 V. Description of the invention (18) The 6th case printed by the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs _ Degree 7.5 of paper mill ingredients against synergistic bioactive biocide (ppm product) for 30 minutes 90 minutes 5 hours 24 hours PAA-25 4. 9xl05 5. OxlO5 2. 5xl06 6. 6xl〇 6 PAA-50 2. 9x105 4.8xl05 4. 2xl06 2. 3xl06 PAA-100 6. 3x104 1.8xl05 4. lxl05 2. 5xl07 0 minutes 60 minutes 4. 5 hours 24 Hours ISO-133 7.4x105 5. lxl〇5 4. 7x105 1.6xl04 ISO-100 7. 3x105 5. 6xl05 5 4. 2xl05 5 1.9xl04 ISO-67 7.8xl05 5. 9xl〇5 3. 8x105 9. 6xl04 ISO-33 8. OxlO5 5.7xl〇5 6. lxl05 5 2. 2x107 PAA-lO / ISO-133 5_2xl05 5 1.6xl05 5 lxl〇5 1. lxl〇4 PAA-lO / ISO-100 3.lxl05 1.4xl05 3.4xl05 2. lxl04 PAA-10 / ISO-67 3. 7x105 2. lxl05 4.8xl05 4. 9xl04 PAA -10 / ISO-33 2. 6x105 2. 2x105 6.4xl0 5 5. 3x106 PAA-25 / ISO-133 1.4xl0 5 6. 7x104 1.lxl05 3. 2xl〇3 PAA-25 / ISO -100 1.6xl05 8. 7xl04 1.2xl05 4. 2xl03 PAA-25 / ISO-67 1.2xl05 + 8. OxlO4 1.4xl05 5. 9xl03 PAA-25 / ISO- 33 1.5xl05 5. 4x; p4 1.6xl05 5 8xl05 PAA-50 / ISO-133 1.8xl04 4 5xl03 3. 3xl03 1.6xl0Z PAA-50 / ISO- 100 1.4xl04 4_8xl03 3xl04 4 2xl02 PAA-50 / ISO-67 3. 3xl04 4 1.2xl04 4 3xl04 4 lxl〇3 PAA-50 / ISO-33 1.9xl04, 2.3xl04, 5.lxl04, 5.4xl03, control group-0 8. 2xl05, 7. lxl05, 2.5x10®, and 3x106. After 90 minutes, « 〇glD reduction: Peracetic acid &gt; 50ppn (ΙΟΟρρ ·) Please read the note on the back first

I This paper size applies to Chinese National Standard (CNS) Α4 specification (210X297 mm) 21 _ Ο 1 _ Consumption cooperation between employees of the Central Bureau of Standards of the Ministry of Economic Affairs DU A 7 403724 _Βτ_ V. Description of the invention (19) 150 &gt; 133ρρ · (167ρρ ·) in case of acetic acid = 25ppHS0 = 67pp · Concordance Index &lt; SI &gt; = 25/100 + 67/167 = 0.65 After 5 hours of SB connection, the following will be reduced to 21 ° gl: «Acetic acid> ; 50ρρ · &lt; 100ρρ · &gt; IS0 &gt; 133pp «(167ρρ ·) peracetic acid &gt; 50ppVIS0 = 33pp · Synergy Index (SI) = 50/100 + 33/167 = 0.70 After 24 hours of contact, reach the following 31ogl. Decrease: »Acetic acid &gt; 50ρρ · (IOOpp ·) IS0 &gt; 133pp« (167ρρ ·) In case of acetic acid = 25ppVIS0 = 67pp · Concordance index &lt; S 丨 &gt; = 25/100 + 67Μ67 = 0 · 65 隹Seven cases were tested in a paper mill that did not apply enough antimicrobial control and that slime began to form on the mechanical surface. It was found that the aerobic bacterial population on the mechanical surface was maintained at 1X107 CFU / «L. At a higher bacteria count, the paper mill 逋5L heterojunction as a single On application of the biocide, a 1.52 isomeric compound of 150ρρ · is required to limit the bacterial population to 5X106 CFU / «L. However, after a long period of time, the paper standard has been applied to the Chinese National Standard (CNS) A4 specifications (210X297 mm) ^ ---!, — I J ---- .. clothing ------ order (please read the note on the back before filling this page). -22-A7 B7 --i097M- 5. Description of the invention (20) (Please read the note on the back-item before filling out this page) The amount is not enough. 10 PP · 4.53: Peracetic acid dissolved and 1.5 from 17:01: !; The combination of 曩 _J9LML pods increased the number of articles to the level of 1X107 CFU / iL. By increasing 1.5;); the iso-pyridoline blend to 33ρρ ·, the fine hair group decreased to 1X1 04 CFU / * L〇 laboratory tests have shown that 4.5Z meets acetic acid dissolution itself 50ρρ · Μ Μ to reduce the fine 0 population to 1X104 [Ρ (] / · ί. This information can be used to calculate the coordination coefficient: To achieve a reduction of 31og ： Single 狝 4.5Z pass acetic acid solution = 50ρρ · House "&gt; 1.5¾Matazoline trace compound &gt; 150ρρ · (200ρρ ·) or 10ρρ · 4.55; Peracetic acid solution + 33ρρ · N-7647 Combination Concordance Factor 10 / 50 + 33/200 = 0.365 Printed by the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs to add 4.5Z »acetic acid to the white water circuit, and to add 1.5Z isosleepazoline blend to the same Application point. As far as the active substance is concerned, when the 1.5Z isialazoline blend is added, the ratio is very close to 1: 1. The fan garden will vary from mill to mill, from 5: 1 to 1.5 for this combination. Based on laboratory data, the ratio of other biocidal compositions in terms of active substances is expected to be from 1: 1 to 1: 200. The present invention reduces the expensive chemicals ft required to inhibit the growth of tritium. As shown in the figure, a composition of 100 ρριΜ biocides, such as carbamate, and a 100PP · dose solution of acetic acid is more effective than a single application of 25ρρ · peracetic acid solution or 200PP · the biocide. Therefore, the present invention provides a more cost-effective and environmentally friendly method for treating microorganisms. This paper size applies to China National Standard (CNS) Α4 size (210X297 mm) 23

Musk c c c

7 7 AB-V. Description of the invention (21 # 8_0 The following experiments were carried out. K showed that »acetic acid and bromoethoxyacetophenone &lt; bhap &gt; Activity. However, it was found that every second biocide is resistant, not synergistic. However, this unexpected result, this experiment shows that peracetic acid is not synergistic for all organic biocides. Biological agent (ppm product) 60 minutes 5 hours 24 hours PAA-25 2. 9x10® 1.7x107 2. 7x107 PAA-50 1.5x10® 4. 7x10® 4. 〇χΙΟ7 ^ PAA-100 1.1x10® 1.6x105 6. 5χ10 1% &gt; w 30 cents 4.5 hours 24 hours BIIAP-12. 5 2.4x10® 9.8xl04 4 5x107 BHAP-25 1.4x10® 2. 7xl04 4 1.7x10? BIIAP-50 6. 0x105 6. 2χ104 I.〇χΙΟ3 BHAP-100 4. 2x105 1.3x104 1.5x102 ΑΛ-10 / ΒΙΙΑΡ-12.5 3. 9xl〇6 6. 〇χΙΟ5 4. 9χ10? PAA-10 / BHAP-25 2. 7x106 1.9x105 1.9x107 PAA -10 / BHAP-50 1.0x10® 8. 5x104 1.8x107 PAA-10 / BHAP-100 2. 0x10® 1. 1x105 9.7 × 10Z PAA-20 / BHAP-12. 5 3. 6x10® 1.2x10® 4. ΙχΙΟ7 PAA -20 / BHAP-25 2. 0x10® 7. ΟχΙΟ5 1.6x107 PAA-20 / BHAP-50 1.8x10® 8.7x104 8. 2χ104 PAA-20 / BHAP-100 1.4x10® 5. 3χ104 3. 2χ102 PAA-40 / BIIAP-12.5 1.5x10 ° 1.9χ106 4. 8χ107 PAA-40 / BHAP-25 1.8x10® 7. ΙχΙΟ4 2. 6χ107 PAA-40 / BIIAP-50 1.4x10® 9. 〇χΙΟ4 2. 〇χΙΟ5 PAA-40 / BIIAP-100 9. Ox 105 6. 7χ104 3 ΟχΙΟ2 Control group-0 7. lxlO6 6. 0x10® Ι.ΟχΙΟ7 Printed by Shelley Consumer Cooperatives, Central Bureau of Standards, Ministry of Economic Affairs (please read the precautions on the back first, and then this page) This paper size applies to Chinese National Standards (CNS) A4 specification (210X297mm) 24 A7 B7 403724 V. Description of the invention (22) Calculation of synergy: After 24 hours of connection, in order to achieve 41ogie reduction: meet acetic acid = &gt; 100 (200) BHAP = 50 meet Acetic acid / BHAP = 10/100 10/200 + 100/50 = 2.05 = Concordance index &lt; SI &gt; The ninth display shows «acetic acid and dibromofluorenylbutane (DBDCB) in paper mill process water with an acidity of 7.0 Synergistic activity against withdrawal. -(Please read the note on the back page first) \ Biocide healing (ppm product) 60 minutes 300 minutes 24 hours ΡλΑ-25 3. 3x106 1.lxlO7 1.3xl〇7 ΡΑΑ-50 6. 4x105 5. 6x10 ® 3. 4x107 ΡΑΑ-100 2. 7xl05 1 · 6x104 3. OxlO7 Ordered by the Central Standards Bureau of the Ministry of Economic Affairs and printed by the Shelley Consumer Cooperative Co., Ltd. This paper applies the Chinese National Standard (CNS) A4 specification (210X297 mm) 25 -OC _ 403724 V. Description of the invention (23) Printed on a piece of paper, 30 cents, 270 minutes, and 24 hours by the Consumer Cooperative of the Central Procurement Bureau of the Ministry of Economic Affairs DBDCB-25 2. lx106, lx104, 5x106 DBDCB-50 2. 2xl06 1. lxl03 1.8xl2 DBDCB-100 3.6xl05 5 0x103 &lt; l〇 '.DBDCB-200 2. 8x105 9. 7x102 &lt; l〇' WA-10 / DBDCB- 25 3. 9x10® 1. lxl〇5 6. 5x102 PAA-10 / DBDCB-50 3.1x10® 8: 2x103 4. 3xl〇2 PAA-IO / DBDCB- 100 1.9x10® 2. 9xl〇3 &lt; 10] PAA-10 / DBDCB- 200 3.7x10® 3. 7x103 &lt; 10 丨 PAA-20 / DBDCB-25 2.6x10® 3.4xl05 5. 9xl03 PAA-20 / DBDCB-50 2. 1x10® 1.3xl〇 3 2. llxIO2 PAA-20 / DBDCB-100 1.8xl〇6 7. OxlO3 4.8X101 PAA-20 / DBDC B- 200 307x106 3. 7xl03 2. lxlO1 PAA-40 / DBDCB-25 1.7x10® 2. 9x104 6. 8x102 PAA-40 / DBDCB-50 1.7x10® 9. lxl〇3 4. lxlO2 PAA-40 / DBDCB- 100 3.3xlO5 2.4xlO3 1.3x10 'PAA-40 / DBDCB-200 2.4xlO5 2. 3x103 &lt; l0' Control group-0 5.5xl06 6.6x10® 7. 4x10® Calculation of cooperation: After 24 hours of contact, in order to achieve a reduction of 41og1D: meet acetic acid => 100 (200) DBDCB = 50 meet acetic acid / DBDCB = 10/25 10/200 + 25/50 = 0.55 = synergy index (SI) Appropriate Applicable Standards for National Standards 7 9 2 ^^ 1 In — ^ 1 «^ 1— ·-(Please read the precautions on the back page first)--. &Quot; 26 A7 B7 -40378 ^ — V. Description of the invention (24 隹 10 supporters showed that peracetic acid and dodecylguanidine hydrochloride were found to resist the synergistic activity of organisms found in white water of the paper mill, pH 7.1, and withdrawal of organisms. Concorde after the 8th occurred in some chemicals, but after 24 hours of static exposure, its effect became resistant. This experiment shows the importance of adding the chemical at the right time interval, and K ensures the desired result. Please read first-read the note ^ 'Note Printed by the Central Bureau of Standards, Ministry of Economic Affairs, Shellfish Consumer Cooperative, printed biocide (ppm product) 60 minutes 300 entries 24 hours PAA-25 3.8xl05 4. 6x10® 4.3x107 PAA-50 2. 5xl〇5 4. 5x10® 2. 7x107 PAA-100 1.9x105 2.0x104 2. ΙχΙΟ7 ψ 30 entries 270 minutes 24 hours 1X111-10 3. 6x105 3.2x10® 2.4x107 DGH-20 3.3xl0 5 4.3χ105 3. ΟχΙΟ7 DGH-40 5.4x104 7. 6x102 6. ΙχΙΟ4 DGH-80 2. 7x102 &lt; 10 丨 2.8x102 PAA-10 / DGH-10 4. 6χ105 4. 0x10® 2.3x107 PAA-10 / DGH-20 1.7 x105 1.2χ105 1.9χ107 PAA-10 / DGH-40 2. 4x103 8.2x102 2. 7x104 PAA-10 / DGH-80 2. 5χ102 &lt; 1〇 '4. 6x102 PAA-20 / DGH-10 4. 9χ105 ^ 4 〇χΙΟ6 1 · 9χ107 PAA-20 / DGH-20 2 · 4χ105 1.2χ105 1.8x107 PAA-20 / DGII-40 1 · 6χ103 2. 9x103 2. 〇χΙΟ7 PAA-20 / DGH-80 3.5χ102 2.8 × 101 2.3χ105 PAA- 40 / DGH-10 1.9x105 9. 8x105 2. ΙχΙΟ7 PAA-40 / DGH-20 3.2x105 1.2x10® 1.6x107 PAA-40 / DGH-40 1.6χ102 2.8x102 1.5x107 PAA-40 / DGH-80 1.6 χ102 1. 9x1ο1 2.〇χΙ〇7 Control group-0 5. 5χ1〇6 6. 6x10® 7.4x106 This paper size applies to China National Standard (CNS) A4 (210 X 297 mm)

II (丨 I ^ page, 27 A7 B7 403724 V. Description of the invention k) Calculation of synergy: After 1 hour of contact, it is 31〇g1 (reduction of l: peracetic acid = &gt; 100 (200) DGH = 50 peracetic acid / DGH = 40/40 40/200 + 40/80 = 0.7 = Synergy Index (SI &gt; The synergy is a rapid 5108 ^ after 24 hours contact. The reduction of peracetic acid = &gt; 100 (200 ) DGH = 80 peracetic acid / DGH = 40 (80 &gt; / &gt; 80 (160〉 80/200 + 160/80 = 2.4 = coordination index (SI)) Anti-resistance mechanism- (Please read the precautions on the back first wtwtC (This page) The standard of printed paper for garments of the Consumer Cooperatives of the Central Economic and Technical Bureau of the Ministry of Economic Affairs applies the Chinese National Standard (CNS) A4 specification (210X297 mm) -〇〇_ 28 40372 ^ V. Description of the invention b) A7 B7 隹 11 Synergistic activity against acetic acid and decylpyroethylamine (DETA) in the white water of a paper mill with an acid age of 7.1 against bioremoval. Printed biocide (ppm product) by the Consumer Cooperative of the Central Standards Bureau, Ministry of Economic Affairs 60 minutes 300 minutes 24 hours PAA-20 6. 5xl0 5 2. 9x10® 8. 4x10® PAA-40 8. 7x104 7. OxlO4 3. lxl07, PAA-80 1.3x10 '2. 9x103 1.8xl〇 7 30 minutes 270 minutes 24 hours DTEA-12.5 l.OxlO7 1. lxl〇7 1.5xl07 DTEA-25 1.2xl07. 1.1 lxl07 7 1.5xl07 DTEA-50 1.2xl09.6 9. 5x10® l_8xl 〇7 DTEA-100 5. OxlO2 1. lxl〇6 3.2xl07 PAA-10 / DTEA-12.5 3. OxlO6 7. 5x10® 1.9xl07 PAA-10 / DTEA-25 3. 5x106 8. 6x10® 1.8 xl〇7 PAA-10 / DTEA-50 2. 7x106 4. 8x10® 3. OxlO7 PAA-10 / DTEA-100 1. lxl〇2 5. OxlO5 3. 4xl〇7 PAA-20 / DTEA-12.5 6. 3xl 〇5 2.1x10® 2. OxlO7 PAA-20 / DTEA-25 7. lxl〇5 1.8x10® 2. 7xl〇7 PAA-20 / DTEA-50 6.3xl〇5 7. 5xl〇5 1.7xl〇7 PAA- 20 / DTEA-100 2.3xlO5 8. 9x104 3. lxl07 PAA-40 / DTEA-12.5 3. 8xl03 7. 3xl03 3.lxl0 PAA-40 / DTEA-25 5. 2xl〇 3 5.2xl02 2 4x107 PAA-40 / DTEA-50 4. 7x103 4. 8xl03 3 6xl07 PAA-40 / DTEA-100 2. 5x103 2. OxlO3 3. 7xl07 Control group-0 1.6xl〇7 1.8xl〇7 1.2xl〇7 1- (Please read the notes of ^^^ this page) This paper size applies to China National Standard (CNS) A4 (210X297 mm) 29 4047 Bismuth A7 B7 V. Description of invention (27) Calculation of synergy After 1 hour of contact, 41ogil (reduced peracetic acid => 80 (160) DTEA = 100 (200) meets acetic acid / DGH = 40 / 12.5 40/160 + 12.5 / 200 = 0.3125 = coordination index ( SI &gt; After 5 hours of contact, the reduction of peracetic acid is 41 〃 to 80 DTEA = &gt; 100 (200) meets acetic acid / DGHM0 / 12.5 40/80 + 12.5 / 200 = 0.5625 = Concordance Index (SI) ( Please read the note on the back of the page first K) * JI. 17 Printed on the paper size of the Zhenggong Consumer Cooperative of the Central Government Bureau of the Ministry of Economic Affairs, this paper applies the Chinese National Standard (CNS) A4 specification (210X297 mm) -30 30 403724 5 2. Description of invention (27) Calculation of synergy: After one hour contact, in order to reach Uogi. Decrease in acetic acid => 80 (160) DTEA = 100 (200) Acetic acid / DGH = 40 / 12.5 40/160 + 12.5 / 200 = 0.3125 = Concordance index (SI &gt; After 5 hours of receiving, it is 逹A decrease of 41 og1D meets acetic acid = 80 DTEA => 100 (200) meets acetic acid / DGH = 40 / 12.5 40/80 + 12.5 / 200 = 0.5625 = Synergy Index (SI) (Please read the precautions on the back first (Fill in this page) The printed paper size of the Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs applies to the Chinese National Standard (CNS) A4 specification (210X297 mm) 30 ¢ 0378 ^ V. Description of the invention (28) A7 B7 flute 12 cases show acetic acid And the original feg (0ΡΑ) in the water of pH 7.0 paper mills against the synergistic activity of the organisms. The central government of the Ministry of Economic Affairs of the Shellfish Consumer Cooperatives printed biocides (ppm products) 150 minutes 270 minutes 24 hours PAA-40 2.3xl〇7 2. 6x107 1.5x107 PAA-80 „1.2x107 1.3x107 1.5x107 PAA-160 4. 2x10® 3. 8x107 1.7x107 # 120 minutes 240 minutes 24 hours 0PA-12.5 2. 5x106. 2χ105 2 · 8χ107 0PA-25 2 · 7χ105 2. ΙχΙΟ5 1.7χ107 OPA-50 4. 3x104 4 1.8χ104 6.4x106 OPA-100 1.5χ103 9. 5χ 102 3. 4χ104 PAA-20 / OPA-12. 5 4. ΙχΙΟ5 2.1x10® 2. 7χ107 PAA-20 / OPA-25 9.7χ104 .1.3x105 1 · 9χ107 PAA-20 / OPA-50 2. ΙχΙ03 1.8χ103 7 ΙχΙΟ6 PAA-20 / OPA-100 7. 2χ102 &lt; 10 丨 4. 8x105 PAA-40 / OPA-12. 5 3. ΟχΙΟ5 2. ΟχΙΟ5 1.5χ107 PAA-40 / OPA-25 5. 4x104 8.9x103 5. 2x10® PAA-40 / OPA-50 9.2χ10ζ 7.4χ102 1.5χ107 PAA-40 / OPA-100 6.4χ107 6. 2χ10Z 5.3χ105 PAA-80 / OPA-12.5 2. 4x105 1.7x103 1.8x107 PAA-80 / OPA-25 3. ΙχΙΟ3 4. 4x102 3. ΙχΙΟ6 PAA-80 / OPA-50 6. ΙχΙΟ2 6. · 7χ102 4. 6χ103 PAA-80 / OPA-100 7.4χ102 5.3χ102 3. 5χ103 Control group-0 2. 5χ107 3. ΙχΙΟ7 1.3 χ107 n ^ i-ll ^ imi nn im ^ i In m I mi mt— ° ·--/-. Note for ib-H to read back t f) This paper size applies Chinese National Standard (CNS) A4 size (210 X 297 mm) 31 ¾ 40372J V. Description of the invention (29)

At B7 Calculation of synergy: After 24 hours of contact, in order to achieve 41ogie reduction of acetic acid = &gt; 160 B20 &gt; 0PA = &gt; 100 (200) peracetic acid / 0PA = 80/50 80/320 + 50/200 = 0.5 = Coordination Index (SI) after 5 hours of contact * is a decrease of 41〇gt »: in case of acetic acid = &gt; 160 (320 &gt; 0PA = 100 in case of acetic acid / 0PA = 80 / 12.5 80/320 + 12.5 / 100 = 0.375 = Concordance Index (SI) Please read the note on the back then &amp; t 4 ~ ii Printed on the paper standard of China National Standards (CNS) A4 specification (210X297 mm) -32-32 403724 V. Description of the invention (30) A7 B7 隹 13 cases of peracetic acid and bromonitropropane di-enzyme (BNPD) in paper mill water with an acidity of 7.0 against microorganisms Synergistic activity. Shellfish consumer cooperation with the Central Bureau of Standards of the Ministry of Economic Affairs. Printed biocide (ppm product) 150 minutes 270 minutes 24 hours PAA-10 2. 8x10® 4. 3x106 9. ΟχΙΟ6 PAA-20 1.6xl05 5 1.3 x105 1.5x10® PAA-40 6. 2x103 1.6x103 8. 5x1Ό4 ψ 120 minutes 240 minutes 24+ hours BNPD-25 7. 2x106 5. 2x106 4. 8x104 BNPD-50 4. 6x 10® 3. 0x10® 2.2x104 BNPD-100 3. 7x10® 6. 4 × 105 2. ΙχΙΟ3 BNPD-100 2. 4x10® 9. 5x104 2. 7x102 PAA-5 / BNPD-25 6. 9x10® 3. 4x106 2. 5x106 PAA-5 / BNPD-50 3. 8x10® 3. 〇χΙΟ6 1. ΙχΙΟ5 PAA-5 / BNPD-100 4. 0x10® 4. 2x105 3. 4x103 PAA-5 / BNPD-200 1.5x10® 4. 8x105 3. 8x102 PAA-10 / BNPD-25 6. 3x105 2. 2x105 8. 7x104 PAA-10 / BNPD-50 3. 7x105 7. 4x104 5_ 6x104 PAA-10 / BNPD-100 1.7xl05 3. 2x104 3. 8x104 PAA-10 / BNPD-200 5. 3x104 5.8x102 2. 3x102 PAA-20 / BNPD-25 1.2xl〇5 4. 6x103 1.4x103 PAA-20 / BNPD-50 l.OxlO5 1.2x103 2. 6x102 PAA-20 / BNPD-100 7. 7x104 5. 9x102 &lt; 10 丨 PAA-20 / BNPD-200 5. lxl〇4 3. 5x102 &lt; 1〇 'control group-0 7. 9xl〇6 9. 2x106 6. 5x10® nuun. ^ 1 nn J, II — (ϋ n IT • · -'e &quot; J I-. (please read the precautions on the back side and then $ this page) This paper size applies Chinese National Standard (CNS) A4 Specifications (210X297 mm) 33 A7 B7 &quot; 403724 V. Description of the invention (31) Calculation of synergy: After receiving the gull within 5 hours, it will be 41ogi . Decrease in acetic acid => 40 (80> N-7639 => 200 (400) β acetic acid / N-7639 = 20/100 20/80 + 100/400 = 0.5 = Coordination Index (SI) in 24 hours After picking plums, it will be reduced to 51ogt〇. Acetic acid = &gt; 40 (80 &gt; N-7639 = &gt; 200 (400) Acetic acid / N-7639 = 20/100 20/80 + 100/400 = 0.5 = Concordance Index (SI) (Please read the notes on the back before filling out this page) Printed by the Central Standards Bureau of the Ministry of Economic Affairs, Shellfish Consumer Cooperative, this paper is sized for the Chinese National Standard (CNS) A4 (210X297 mm) 34 Ministry of Economic Affairs Printed by the Consumer Standards Cooperative of the Central Bureau of Standards 403724 ^ _B7_ V. Description of the Invention (32) Di 14 shows that acetic acid and di-dithiophen-3-one (RYH-86NA) are present in the water of a paper mill with a pH of 7.0 (degree 7.0) Synergistic activity against withdrawal. Biocide (ppm product) 60 minutes 240 minutes 24 hours PAA-12.5 2. 3x106 6. 9x10® 3. 2x10® PAA-25 2. 7x105 3. 7x10® Ι.ΟχΙΟ7 、 PAA-50 1.2x104 2. 6χ104 4.5χ107 \ γ 30 minutes 210 minutes 24 hours RYH-86NA-5 2. 6x10® 3. 6x10® 1.5χ107 RYH-86NA-10 1.4xl0 5 2.3χ104 1.4χ107 RYH-86NA -20 2. 3xl〇4 4.2χ103 4. ΟχΙΟ6 RYH-86NA-40 1.4x104 4. ΟχΙΟ3 2.7x103 PAA-10 / RYH-86NA-5 1.9χ105 4. ΟχΙΟ5 2. 9x107 PAA-10 / RYH-86NA-10 4.6x103 2 8 × 103 4. 7x10® PAA-10 / RYH-86NA-20 2. 7 × 103 3. 〇χΙΟ3 2. 6x10® PAA-10 / RYH-86NA-40 2. 5 × 104 1 · 6χ103 3. 〇χΙΟ3 PAA-20 / RYH-86NA -5 2. 3χ104 3. 6χ103 2. 7x106 PAA-20 / RYH-86NA-10 4. 2χ103 Ι3.4χ103 7. 8χ106 PAA-20 / RYH-86ΝΑ-20 3.ΙχΙΟ4 3. 6χ103 3. 1x10® PAA- 20 / RYH-86NA-40 2.5 × 104 1.6 × 104 1.7 × 104 PAA-40 / RYH-86NA-5 2. 7 × 104 4. 1 × 104 1.9 × 107 PAA-40 / RYH-86NA-10 1.8x104 4.6x104 1.2x107 PAA-40 / RYH -86NA-20 2. 4χ104 1.8χ104 1.4PD107 PAA-40 / RYH-86NA-40 2. 6χ104 2.4χ104 6. 5χ106 Control group-0 3. 5x10® 1.9χ106 3 · 4χ106 This paper size is applicable to Chinese national standards (CNS) A4 specification (210X297 mm) II In n • * &quot;, T (Please read the note on the back before filling in this page)-35 A7 B7 403724 V. Description of the invention (33) Calculation of cooperation : To achieve 31ogie reduction after 4 hours of contact Peracetic acid = &gt; 50 (100) RYH-86NA = 20 meets acetic acid / RYH-86NA = 10/10 10/100 + 10/20 = 0.6 = coordination index (SI &gt; »acetic acid / RYH-86NA = 20/5 20/100 + 5/20 = 0.45 = Concordance Index (SI &gt; (Please read the precautions on the back before filling out this page) Printed on the paper by the Consumer Standards Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs, China National Standard (CNS) A4 Specifications (210X297 mm) 36 «Οί:-40372; A7 B7 V. Description of the invention (34) m.um shows that it meets acetic acid and two gases -η-octyl isomozoline (RH-287) at a pH of 7.1 The synergistic activity of the paper mill in white water against biological withdrawal. Printed biocide (ppm product) in the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs 60 minutes 240 minutes 24 hours PAA-12. 5 3. lxlO6 5.4x10® 3. 9xl07 PAA-25 2. 7x105 1.9xl〇6 5 .OxlO7 PAA-50 1.3xl0 5 8. 4x104 7.8xl07 7 30 minutes 210 minutes 24 hours RH-287-25 4. 6xl〇6 1.5xl07 6.4xl07 7 RH-287-50 4.lxlO6 1.2 xl〇7 3. 6xl07 RH-287-100 4.6x10® 2. 3xl06 2.8xl07 RH-287-200 3. 9xl06 1.lxlO5 2. 6xl07 PAA-10 / RH-287 -25 3.8x106, 4x106, 5.8x106, PAA-10 / RH-287-50 3.4x106, 2.0x10® 3. 8x107, PAA-10 / RH-287-100 2. lx10, 1.3 xl〇5 2. 4xl07 PAA-10 / RH-287-200 7. 3xl〇5 2. OxlO4 2. 3xl07 PAA-20 / RH-287-25 5. lxlO5 4. 8x105 6. 3xl〇7 PAA-20 / RH-287-50 4. 4xl05]. 8xl05 6. lxl07 PAA-20 / RH-287-100 3.2xl05 5. OxlO4 3.5xl07 PAA-20 / RH-287- 200 1.2xl05 7. 3xl03 2. 3xl07 PAA-40 / RH-287-25 2. 3xl05 7. lxlO4 6. lxlO7 PAA-40 / RH-287-50 2.lxlO5 4.OxlO4 6.2xl07 PAA-40 / RH-287-100 1.5xl〇5 2. 3xl〇4 4. 7xl0? PAA-40 / RH-287-200 2. OxlO5 1.9xl 〇4 2. OxlO7 control group-0 4. 8xl〇6 4. 6xl〇6 2.3xl〇7 n-I * 7S--* '----- I n II---I …… -Ή (Please (Please read the notes on the back before filling this page) ·--This paper size is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm) 37 A7 B7 j〇3724 V. Description of the invention (35) Calculation of cooperation: After 4 hours of contact, it is reduced by 31 og * e to meet acetic acid => 50 (100) RH-287 => 200 (400) peracetic acid / RH-287 = 20/200 20/100 + 200/400 = 0.7 = Concordance Index (SI &gt; (Please read the notes on the back before filling out this page) Printed on the paper by the Consumer Standards Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs, China Paper Standard Applicable to China National Standard (CNS) A4 (210X297 mm) 38 403724 A7 B7 V. Description of the invention (36) The 1fi example shows that it meets acetic acid and 1- (3-panallyl) -3,5,7-triaza-bupronium-free gold alkaneamide (D75) in Synergistic activity against the withdrawal of organisms in white water of a paper mill with a pH of 7.1. Employees of the Central Bureau of Standards of the Ministry of Economic Affairs, Consumer Co-operative Biocide (ppm product) 60 minutes 240 minutes PAA-25 1.6xl0 5 1. 7x105 PAA-50 1.4xl0 4 2. OxlO5 PAA-100 3. 2xl0 3 2 7x102 30 minutes 210 minutes D75-50 4. OxlO5 7. 2x104 D75-100 3.7xl0 5 6. 7xl0 4 D75-200 2. 9xl0 5 6. OxlO4 D75-400 3. 5xl0 5 6. 3xl〇 4 PAA-10 / D75-50 2. 4x105 9. 9x104 PAA-10 / D75-100 2. lxl〇5 5. 8x104 PAA-10 / D75-200 1.6xl〇5 2. 5xl〇4 PAA-10 / D75 -400 1.9xl0 5 2. 8x103 PAA-20 / D75-50 2. lxl0 5 1. lxl0 5 PAA-20 / D75-100 2. 6xl0 5 8. 7x104 PAA-20 / D75-200 2. 6xl〇5 l_6xl〇5 PAA-20 / D75-400 2.2xl〇5 8. 2xl〇3 PAA-40 / D75-50 1.9xl〇5 8. lxl〇4 PAA-40 / D75-100 2. OxlO5 1 lxl〇5 PAA-40 / D75-200 1.8xlO5 5.2xl〇4 PAA-40 / D75-400 1.6xlO5 6. 5xl03 control group-0 6. lxl05 5 5x106 ^ n- m, —n 1 ^ 1 (^ 1 an · In I HI t * 0 V.. &quot; i (Please read the notes on the back before filling in this page) · 'This paper size applies Chinese National Standard (CNS) A4 Specifications (210 X297 mm) 39 r. · 40372 4 V. Description of the invention (37 A7 B7%! Calculation of synergy: After 4 hours of contact, in order to achieve a reduction of 21 oglO meet acetic acid = 100 D75 => 400 (800) peracetic acid = 10ρρ · / Ι) 75 = 400ρρ · Concordance Index (SI) = 10/100 + 400/800 = 0.60 (Please read the precautions on the back before filling out this page) The printed paper size of the Central Government Bureau of Standards, Consumer Consumption Cooperative, applies Chinese national standards ( CNS) A4 specification (210X297 mm) 40 403724 \ Ί Β7 V. Description of the invention (38 «M7 has shown that it meets acetic acid and bis (trimethylethane) code (BTCMS) against 撖 in the white water of a paper mill with a acidity of 7.1 Synergistic activity of organisms.

II Printed biocide (ppm product) by the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs 60 minutes 240 minutes 24 hours PAA-25 7. OxlO5 8. OxlO5 1. 7x106 PAA-50 7. Oxl 05 1.9xl〇6 5. 4xl 〇6 PAA-100 8. OxlO5 8. lxlO5 9. 6x10® r: · Ί 30 minutes 210 minutes 24 hours BTCMS-10 5. OxlO5 8. OxlO4 8.4x10® BTCMS-20 1.lxlO6 1. 2x105 9. 2xl〇 6 BTCMS-40 8. OxlO5 5. 9xl〇4 1.7x10® BTCMS-80 1.lxlO5 4. 6xl〇4 1.3xlO5 PAA-10 / BTCMS-10 1.5x10® 6. OxlO5 8. 6x10® PAA-10 / BTCMS-20 4. OxlO5 6. 5xl〇4 4.6x10® PAA-10 / BTCMS-40 1. lxlO5 6. 3xl〇3 5. lxlO4 PAA-10 / BTCMS-80 5. lxlO4 4. 7xl〇2 4. 5xl〇2 PAA-20 / BTCMS-10 1.lxlO5 1.0x10s 6. OxlO6 PAA-20 / BTCMS-20 3. OxlO5 1. lxlO3 1. lxlO7 PAA-20 / BTCMS-40 1.0x10s 8. 5xl〇2 2. OxlO6 PAA-20 / BTCMS-80 2.6xl04 6. OxlO3 1.2xl03 Control group-0 9. OxlO5 1.4xl06 2. OxlO6 Calculation of synergy: After 4 hours of exposure, to achieve a reduction of 31oglD : In case of acetic acid = &gt; 100 (200 &gt; BTCMS = &80; 160 (160) CNS) A4 specification (2 丨 OX297mm)! 1 ^ ~ 丨 7 ^-(Please read the precautions on the back before filling this page)

, TT 41-403724 Printed by the Consumer Cooperatives of the Central Standards Bureau of the Ministry of Economic Affairs A7 B7 V. Description of the invention (39) Peracetic acid = 10pp ^ / BTCMS = 40pp · Concordance Index (SI) = 10/200 + 40/160 = 0.3 Peracetic acid = 20pp ^ / BTCMS = 20pp · Synergy Index (SI) = 20/200 + 20/160 = 0.225 After 4 hours of contact, 31ogt was reached. Decrease in case of acetic acid = &gt; 100 (200) BTCMS = &gt; 80 (160) Peracetic acid = 10pp «/ BTCMS = 80pp · Synergy Index (SI) = 10/200 + 80/160 = 0.55 Peracetic acid = 20pp * / BTCMS = 80pp · Concordance Index (SI) = 20/200 + 80/160 = 0.60 This paper size is applicable to China National Standard (CNS) A4 specification (210X297 mm) 42 ——— V. Description of the invention (4〇 ) A7 B7 隹 18 Cooperation and Cooperation Study: Eaves used in the composition of acetic acid (PAA) and iso-azole_ 醑: 录 保 捍 (PA01) * Typical cooling water details Water: Synthetic cooling water (# 13, adjust to pH 7.0)

The time stamped by the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs = 0 CFU / ML time = 24 hours CFU / ML _ Control group (without added biocide) 9.3 e 6 2.0 e 7 f Only peracetic acid (PAA) products are added # pm 2.7e7 8 ppm of product 1. 5 e 6 of product 16 ppm 4. 7 e 4 of product 32 ppm 4.7 e 3 of product 40 ppm 2.0 e 2 Add only 1 isocyanate product 10 ppm 5.7 e 6 of product 20 ppm &lt; / 1. 0 e 6 of the product 40ρριπ 1. 0 e 6 of the product 50ppm 6.4 e 5 of the product 75ppm 7.7e4 of the product 100ppm 4.0 e 3 (please read the note on the back before filling this page). The paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 gong) 403724 V. Description of the invention (u) A7 B7 Peracetic acid (5ppm of product) printed by the Consumer Cooperatives of the Central Standards Bureau of the Ministry of Economic Affairs + isoryllinone 10 ppm of product 2.3 e 5 20 ppm of product 1.0 e 5 40 ppm of product 3. 0e3 50 ppm of product 2. 7e3 75 ppm of product 1.2e3 and 100 ppm of product 4.0e 2: Salicylacetic acid (10 ppm of product) + Isophorin LOppm 5. 4 e 4 20ppm of material 4.4 e 3 of product 40 ppm 5.7 e 3 of product 50 ppm 7.2 e 2 of product 75 ppm 1.0e2 of product 100 ppm 4.8 e 2 Synergy Index: (5 mouth 111 peracetic acid +4 (^ 0 [11 异 " «1 You Linming: 0.125 + 0. 5 = 0. 525 (&lt; 1.0), synergy (please read the precautions on the back before filling this page) The paper size of the paper is applicable to China National Standard (CNS) A4 (210X297 mm) 44 403724 'kl B7 V. Description of the invention (43) The creation of God and His Majesty, and will not damage the advantages of desire. Therefore, this change and Iridium will be ashamed of the attached benefits (Please read the precautions on the back before filling out this page) — &lt; Order the paper size printed by the Consumer Cooperatives of the Central Standards Bureau of the Ministry of Economic Affairs to apply the Chinese National Standard (CNS) A4 specification (210X297 mm). 46 —

Claims (1)

A8 B8 C8 D8 Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs ^, Patent Application No. 85114459, Patent Reexamination, Application for Patent Scope Amendment, Date of Amendment: December 88, 1 · A composition for inhibiting the growth of microorganisms in water systems. Containing an effective amount of peracetic acid and a non-oxidizing biocide, the non-oxidizing biocide is selected from the group consisting of: decylthioethylamine, orthophthalaldehyde, dodecylguanidine hydrochloride, 1- ( 3-Gas allyl) -3,5,7-triaza-1-azoadamantane gaseous compounds, dibromodicyanobutane and bis (trifluoromethyl) 该 'the peracetic acid and non-oxidizing The number of sexual biocides was selected to produce a synergy effect index of less than one, where the calculation of the synergy effect index was determined by determining a first ratio, which was the amount of peracetic acid and non-oxidizing biocide The amount of peracetic acid required to produce a degree of microbial growth inhibitory effect when the biological agents are added in combination is relative to the amount of peracetic acid required to produce a degree of microbial growth inhibitory effect in the absence of non-thinning biocides. Volume ratio , The first ratio is added to a second ratio, the second ratio is the amount of non-oxidizing biocide added and the amount of peracetic acid required to produce a degree of microbial growth inhibition The ratio of the amount of oxidizing biocide to the amount of non-oxidizing biocide required to produce a degree of microbial growth inhibition in the absence of peracetic acid. 2. The composition according to item 1 of the patent application range, wherein the amount of peracetic acid is from 5 to 250 ppm and the amount of the non-oxidizing biocide is from 10 to 250 ppm. 3. —A method for controlling the growth of microorganisms in industrial treatment water, which method involves the input of a sufficient amount of peracetic acid and a sufficient amount of non-oxidizing properties. This paper applies the Chinese National Standard (CNS) A4 specification (210 X 297cm) (Please read the notes on the back before filling out this page) ^ · 1 II — III · 11111111. IIII-A8 B8 C8 D8 Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs ^, Patent Application No. 85114459, Patent Reexamination, Application for Patent Scope Amendment, Date of Amendment: December 88, 1 Containing an effective amount of peracetic acid and a non-oxidizing biocide, the non-oxidizing biocide is selected from the group consisting of: decylthioethylamine, orthophthalaldehyde, dodecylguanidine hydrochloride, 1- ( 3-Gas allyl) -3,5,7-triaza-1-azoadamantane gaseous compounds, dibromodicyanobutane and bis (trifluoromethyl) 该 'the peracetic acid and non-oxidizing The number of sexual biocides was selected to produce a synergy effect index of less than one, where the calculation of the synergy effect index was determined by determining a first ratio, which was the amount of peracetic acid and non-oxidizing biocide The amount of peracetic acid required to produce a degree of microbial growth inhibitory effect when the biological agents are added in combination is relative to the amount of peracetic acid required to produce a degree of microbial growth inhibitory effect in the absence of non-thinning biocides. Volume ratio , The first ratio is added to a second ratio, the second ratio is the amount of non-oxidizing biocide added and the amount of peracetic acid required to produce a degree of microbial growth inhibition The ratio of the amount of oxidizing biocide to the amount of non-oxidizing biocide required to produce a degree of microbial growth inhibition in the absence of peracetic acid. 2. The composition according to item 1 of the patent application range, wherein the amount of peracetic acid is from 5 to 250 ppm and the amount of the non-oxidizing biocide is from 10 to 250 ppm. 3. —A method for controlling the growth of microorganisms in industrial treatment water, which method involves the input of a sufficient amount of peracetic acid and a sufficient amount of non-oxidizing properties. This paper applies the Chinese National Standard (CNS) A4 specification (210 X 297 gong) (Please read the notes on the back before filling this page) ^ · 1 II — III · 11111111. IIII--403724 6. Application scope of patent (please read the notes on the back before filling out this page) Kill A step of inhibiting the growth of microorganisms by biological agents in the industrial process water, the non-oxidizing biocide is selected from the group consisting of decylthioethylamine, orthophthalaldehyde, dodecylguanidine argonate, 1_ ( 3_Ga allyl 3,5,7-diaza-1-azoadamantine gaseous, dibromodicyanobutane and bis (trichloromethyl) 飒 'The non-oxidizing biocide was selected In order to create a synergy index of less than 1, the calculation of the synergy index is to determine a first ratio, which is the combination of the amount of peracetic acid and the amount of non-oxidizing biocide when added Microbial growth inhibition The ratio of the amount of peracetic acid required for the degree of relative to the amount of peracetic acid required to produce a degree of microbial growth inhibition in the absence of non-oxidizing biocides. Add this first ratio to a second ratio. The second ratio is the amount of non-oxidizing biocide required to produce a degree of microbial growth inhibition when the amount of non-oxidizing biocide added is combined with the amount of peracetic acid, relative to the amount of non-peracetic acid The ratio of the amount of non-oxidizing biocide required to produce the degree of microbial growth inhibition when present. Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs. It is selected from the following groups: water of pulp and paper mill system, cooling water and mining water. 5. The method according to item 3 of the patent application, wherein the peracetic acid and the non-oxidizing biocide are 10: 1. A ratio of 1:25 is added. 6. As in the method of claim 3, the amount of peracetic acid added is from 5 to 250 ppm, and the non-oxidizing biocide added -2- Paper scale applicable Chinese National Standard (CNS) A4 size (210 X 297 male love) 403724 6. The amount of patent application ranges from 10 to 250 ppm. 7. Method of applying for the third item of the patent scope. Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs. This paper size applies to China National Standard (CNS) A4 (210 X 297 male «) (Please read the notes on the back before filling this page) ---- Order --------- Line ·