經滴部中央標率局貝工消费合作社印 A7 ------ B7__ 五、發明説明（/ ) ~~~ 本發明係與有機化合物有關，尤其是關於一種具良好 穩定水分散性之水基乳劑及其製造方法及其製造方法。 就有機化學之領域而言，由於有機化合物與高極性之 水並不互溶，因此在應用有機化合物時通常即以有機溶劑 5將其溶解豨釋之後再供使用，如一般生活中所用以稀釋油 漆之松香水即為一例，但由於有機溶劑大多係具有易燃性 舆毒性等化學性質，因此以有機溶劑作為稀釋有機化合物 之使用方式，不僅會對使用者會造成健康上之危害，且對 地球自然環境亦有嚴重程度之負面影響。 10 而為避免有機溶劑所可能造成之危害，既有技術中即 有將有機化合物予以製成高濃度水基乳劑，Emulsi〇n in Water)，藉以令使用者可以水將此等水基乳劑予以稀 釋成適當濃度使用’如農業產業中經常使用之農藥藥劑即 有以此等方式製成者。 15 惟以既有之水基乳劑而言’其所存在之缺失係在高濃 度之乳劑本身即會產生分層之現象，而使得溶有有機化合 物之有機溶劑與水彼此分離。 且在實際使用上，當使用者將水基乳劑與水體混合成 稀釋液體時’由於水基乳劑在懸浮分散於水體中之穩定狀 20 態不佳’因而在一段時間之後，此等分散之水基乳劑微胞 即會因相互之吸引或合併形成較大之顆粒，而與水體分離 開來，造成其稀釋後之濃度不能保持穩定，而有礙使用。 另以已商品化之水基乳劑來看，一般之胃用乳膠於飲 用之前需先加以搖晃以使其内部混合均勻者，即係為克服 本紙張尺度適用中國國家標準（CNS ) A4規格（2丨0X297公釐） (請先聞讀背面之注意事項再填寫本頁)A7 ------ B7__ printed by the Shell Standard Consumer Cooperative of the Central Standards Bureau of Dibu Department V. Description of the invention (/) ~~~ This invention is related to organic compounds, especially a kind of water with good and stable water dispersion. Base emulsion, its manufacturing method and its manufacturing method. In the field of organic chemistry, organic compounds are not mutually soluble with highly polar water. Therefore, when organic compounds are applied, they are usually dissolved in organic solvent 5 and released before use, as used in ordinary life to dilute paint. Zhisong perfume is an example. However, since most organic solvents have chemical properties such as flammability and toxicity, the use of organic solvents as dilution organic compounds will not only cause health hazards to users, but also cause harm to the earth. The natural environment also has serious negative effects. 10 In order to avoid the possible harm caused by organic solvents, in the prior art, organic compounds are made into high-concentration water-based emulsions (Emulsión in Water), so that users can apply these water-based emulsions to water. Diluted to the appropriate concentration and used 'such as pesticide pesticides often used in the agricultural industry are made in this way. 15 However, in the case of existing water-based emulsions, the lack is that the high-concentration emulsion itself will delaminate, so that the organic solvent in which the organic compound is dissolved and water are separated from each other. And in practical use, when the user mixes the water-based emulsion with the water body to form a diluted liquid, 'because the stability of the water-based emulsion in suspension and dispersed in the water body is not good 20', so after a period of time, these dispersed water The microemulsions of the base emulsion will be separated from the water body due to the attraction or combination of each other, which will cause the concentration of the diluted emulsion to remain stable and prevent its use. In terms of commercialized water-based emulsions, the general gastric latex needs to be shaken before drinking to make it mix evenly inside, which means that in order to overcome this paper standard, China National Standard (CNS) A4 specification (2丨 0X297mm) (Please read the notes on the back before filling in this page)
經濟部中央標率扃貝工消费合作社印？ 本 A7 —^_____B7_ 五、發明説明（2 ) 水基乳劑本身之分層現象；或如水性漆品，其在經水稀釋 後一段時間’漆料即會沉澱而與水分離，致令使用者需再 以外力加以攪拌以使其稀釋均勻俾繼蹟使用，前述商品由 於每次之使用量並不大，因此尚可以手動方式克服水基乳 5劑分散不均之狀態，除使用不便之外尚不致造成其他不良 之影嚮。 但在農業上所使用之藥劑，則有可能因習用水基乳劑 分散性不佳之因素而造成農作物之傷害，其因肇於農用藥 劑通常係以大量之水體加以稀釋，其稀釋倍數更可至數千 10 倍’加以國内農地使用大多係小區經營，並不如國外大區 經營般可投注甚大之機具成本，因此國内之農務從事者大 多僅藉簡單的農具進行藥劑之喷灑，如此一來，當水基乳 劑因其本身之分散性不佳因素而與水體分離成分層時，農 務從事者並不能方便地以手動方式將之再行混合均勻，從 15 而造成所喷灑者若非為原本用以稀釋之水體、即為高濃度 之農藥藥劑，而不論其濃度係過之亦或不及，對於農作物 均有負面之影嚮》 而導致習用水基乳劑分散性不佳之主因係在於其組態 上之不良： 20 習用水基乳劑之製成係將有機化合物原體溶解於少量 之有機溶劑之中，然後再舆溶有界面活性劑之水溶液混 合，生成高濃度之乳液，並對該乳液施以高速度、高剪力 之攪拌，使之形成顆粒細小之乳液微胞，以期減緩水基乳 劑之分層狀態； -4- 本紙張尺度適用中國國家標準（CNS ) A4規格（210X297公釐） ' ~ (請先閱讀背面之注意事項再填寫本頁) 装. *11 經濟部中央標率局員工消費合作社印裝 A7 B7 五、發明説明（^3 ) 而以此等習用製法製成之水基乳劑，其係使每一個乳 液微胞為水/油（w / 〇，水滴在油中）之狀態，即水溶液中之 水體被包覆於溶有有機化合物原體之有機溶劑中，因此當 以水將該水基乳劑稀釋時，因其外圍為油相而造成其難以 5 與稀釋用水體能快速、均勻地混合，並導致其混合後之水 分散性不佳》 因此，本發明之主要目的即在提供一種具良好穩定水 分散性之水基乳劑及其製造方法及其製造方法及其製法， 其可減低水基乳劑本身之分層現象。 10 本發明之再一目的則在提供一種具良好穩定水分散性 之水基乳劑及其製造方法及其製造方法及其製法，其可以 穩定地懸浮分散於稀釋液體之中，從而使其稀釋後之濃度 維持穩定。 緣是，為達成上述目的，本發明所提供具良好穩定水 15 分散性之水基乳劑及其製造方法及其製造方法，係令構成 .乳劑之乳液微胞形成為水滴在油滴中、且油滴在水中之水/ 油/水型，俾使微胞之最外層為水，藉以使水基乳劑本身維 持一良好之不分層效果，並可在以水為稀釋劑時，可以快 速且均勻地分散於水中，藉以使稀釋後之濃度保持於一適 20 當之範圍中，不會產生分層或急劇之濃度變化，以利使 用；而用以製成該水基乳劑之製法係將有機化合物經適當 調配而與H20水形成乳液微胞為水油型之乳劑基質之後， 再予以加入H2〇，以使微胞再進一步成形為水/油/水型， 俾以製成具良好穩定水分散性之水基乳劑及其製造方法及 本紙張尺度適用中國國家標準（CNS ) A4規格（2 ] 0 X 297公釐） ?-1 I ------ -=----1. · -j -I - 1 - I 1--- - ( f In ....... ί -=— - -^h. - - - · (請先閱讀背面之注意事項再填寫本頁) 經濟部中央標準局員工消費合作社印" A7 B7 五、發明説明（/ ) 其製造方法。 以下，茲舉本發明兩較佳實施例，藉以說明本發明之 特點及其功效，其中* 第一圖為水/油型乳液微胞.之示意._圖。 5 第二圖為水/油/水型乳液微胞之示意圖。 本發明所提供之製造方法，係可用於農業用藥劑之製 造，此處所指之農業用藥劑係可區分為殺蟲劑、殺草劑以 及殺菌劑，而其中，殺蟲劑包含了有機磷類、氨基甲酸鹽 類、除蟲菊類；殺箄劑則指可溶於一般有機溶劑之選擇性 10 殺草劑；殺菌劑則包含了有機氣類、有機磷類、有機氨類 以及氨基甲酸鹽類。 本發明之一較佳實施例係為含除蟲菊精之水基乳劑， 其製造方法係包含有下列步驟： a )製備水相趙：取蒸館水，加入少量之消泡劑與適量 15 之界面活性劑，並經擾拌而成均勻之水溶液混合物； b) 製備有機相體：將含除蟲菊精之有機化合物原體， 以適量之有機溶劑予以溶解並經攪拌混合均勻； c) 對該水相體施以攪拌，並於攪拌之同時將有機相體 逐滴加入該水相中，以使有機相體與水相體彼此分散而形 20 成為水/油（W/0)型微胞之乳液基質（如第一圖所示）； d) 於該乳液體中添加少量之殺菌劑與黏稠劑，並經均 勻攪拌； e) 對該乳液髏施以攪拌，並取蒸餾水緩慢加入，經混 合均勻後即生成水/油/水（W/0/W)型微胞之乳液成品（如第 -6- 本紙張尺度適用中國國家標準（CNS ) Λ4規格（210X297公釐) ^----—丨^-I勹装丨丨 (請先閱讀背面之注意事項再填寫本頁) 訂 A7 _______B7 五、發明説明（5"*) 二圖所示）。 其中，在a)步驟與e)步驟中所取用之蒸餾水量，其重 量比例介於6:4與9:1間者係為適當之取用比例。 而在本發明另一較佳實施例者則為含有機磷或酯類有 5機化合物之水基乳劑，此兩種有機化合物之製造方法大體 上係與前揭除蟲菊精水基乳劑之製法相同，所不同者係在 有機磷或酯類水基乳劑之製成時，係於有機相體之製備 中，再添加一選自碳原子總數介於6至丨〇個間之適量醇類 化合物作為抗凝劑，用以降低乳液基質之界面張力，藉以 10形成顆粒細小之水/油型乳液微胞，俾以在製成水/油/水型 微胞之乳液成品時’可具有良好之物理安定性。 前述兩較佳實施例，發明人並針對各個水基乳劑之分 層效應（separation)、有效成分以及粒徑分佈作一持續 性之檢測，且其結果確較既有水基乳劑具有更佳之物理安 15定性質。 分層效應：將各個水基乳劑靜置於室溫下，每隔一個 星期以目視觀察其分層之情形，其結果如下： .1---1.1-\---1·^I— (請先閲讀背面之注意事項再填寫本頁) 訂 經濟部中央榡车局員Η消費.合作社印？衣 取樣時間 除蟲菊精 有機磷 酯類 水基乳劑 水基乳劑 水基乳劑 1 k 未分層 未分層 未分層 8天 未分層 未分層 未分層 14天 極少量 極少量 極少量 21天 極少量 極少量 極少量 28天 少量 少量 少量~~ CNS ) Μ規格(210X297::) 398182 A7 B7 五、發明説明（公） 35天 約總體積1/8 少量 約總體積1/8 42天 約總體積1/7 約總體積1/8 約總體積1/8 49天 約總體積1/6 約總體積1/8 約總體積1/6 56天 約總體積1/6 約總體積1/8 約總體積1/6 有效成分檢測：將兩份之水基乳劑成品分別置於〇°c及 5 0 aC中，每隔一個星期予以取樣並以氣相層析測定法（GC ) 檢驗其有效成分，其結果如下： 經濟部中央榡準局員工消費合作社印製 取樣時間 除蟲菊精 水基乳劑 有機磷 水基乳劑 酯類 水基乳劑 0°C 50°C o°c 50°C o°c D〇°C 1天 "" ... 19. 4% 19. 2% 21. 6% 21.6% 20.6% 19. 6% 8天 19. 0% 19. 0% 21.6% 21.8% 18. 0% 19. 2% 14天 18. 4% 18. 6% 21.2% 20. 4% 19. 8% 21. 6% 21天 18. 4% 18. 8% 20. 4% 19. 8% 19. 4% 19. 2% 28天 18. 2% 18. 8% 19. 8°ί 19. 2% 18.0% 22. 4% 35天 18. 0% 19. 0% 20. 2% 20. 0% 20. 6% 23. 2% 42天 18. 2% 18. 4% 20. 8% 21. 6% 21. 2% 20. 6% 49天 20. 8% 19. 0% 19. 8% 18. 8% 18. 0% 20. 0% 56天 19. 8% 18. 2% 17. 8% 18. 2% 19. 8% 18. 4% ：-------f 裝丨— -· (請先閱讀背面之注意事項再填寫本頁) 訂Printed by the central government of the Ministry of Economic Affairs? This A7 — ^ _____ B7_ V. Description of the invention (2) The delamination phenomenon of the water-based emulsion itself; or, for example, water-based paints, after a period of time after dilution with water, the paint will precipitate and separate from water, causing the user to It needs to be stirred with an external force to make it evenly diluted and used. The aforementioned products are not used every time, so you can still manually overcome the uneven dispersion of the water-based emulsion 5 agents, except for the inconvenience of use. Has not caused other adverse effects. However, the pesticides used in agriculture may cause damage to crops due to the poor dispersibility of water-based emulsions. The agricultural pesticides are usually diluted with a large amount of water, and the dilution factor can reach thousands. 10 times' the domestic farmland use is mostly a community operation, which is not as expensive as the operation of foreign large area operations. Therefore, most domestic agricultural practitioners only use simple agricultural tools to spray medicine. When the water-based emulsion is separated from the water body due to its poor dispersibility, the farmer cannot easily mix it evenly by hand, which causes the sprayed person to be the original if it is not the original The diluted water body is a high-concentration pesticide, regardless of whether the concentration is too high or too low, which has a negative impact on crops. The main reason for the poor dispersibility of water-based emulsions lies in its configuration. Disadvantages: 20 The preparation of water-based emulsion is to dissolve the original organic compound in a small amount of organic solvent, and then dissolve it with interfacial activity. The aqueous solution is mixed to form a high-concentration emulsion, and the emulsion is stirred with high speed and high shear force to form fine-grained emulsion cells, in order to slow down the layered state of the water-based emulsion; -4- this paper Standards are applicable to China National Standard (CNS) A4 specifications (210X297 mm) '~ (Please read the precautions on the back before filling this page). * 11 Printed by the Consumer Standards Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs A7 B7 V. Invention Explanation (^ 3) And the water-based emulsions made by these conventional manufacturing methods are such that each emulsion cell is in the state of water / oil (w / 0, water droplets in oil), that is, the body of water in the aqueous solution is coated Covered in an organic solvent in which the original organic compound is dissolved, so when the water-based emulsion is diluted with water, it is difficult to make it because of its oil phase. 5 It can be quickly and uniformly mixed with the diluted water body and cause it to mix. Therefore, the main object of the present invention is to provide a water-based emulsion with good and stable water-dispersibility, its manufacturing method, its manufacturing method, and its manufacturing method, which can reduce the water-based emulsion itself. Stratification. 10 Another object of the present invention is to provide a water-based emulsion with good and stable water dispersibility, its manufacturing method and its manufacturing method, and its manufacturing method, which can be stably suspended and dispersed in a diluted liquid, so that after dilution The concentration remained stable. The reason is that, in order to achieve the above-mentioned object, the water-based emulsion with good water-dispersibility provided by the present invention and the manufacturing method and manufacturing method thereof are constituted. The emulsion cells of the emulsion are formed as water droplets in oil droplets, and The water / oil / water type of oil droplets in water, so that the outermost layer of the cells is water, so that the water-based emulsion itself maintains a good non-stratified effect, and when water is used as a diluent, it can quickly and Disperse evenly in water, so that the concentration after dilution is kept in an appropriate range, and there will be no stratification or sharp concentration change for the convenience of use; and the method for making the water-based emulsion will be The organic compound is formulated with H20 water to form an emulsion cell with a water-oil type emulsion base, and then H2O is added to further shape the cells into a water / oil / water type. Water-dispersible water-based emulsion, its manufacturing method and the paper size are applicable to Chinese National Standard (CNS) A4 specification (2) 0 X 297 mm)? -1 I -------= ---- 1 · -J -I-1-I 1 ----(f In ....... ί-= —--^ h.---(( Please read the notes on the back before filling in this page) Printed by the Consumers' Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs " A7 B7 V. Description of the invention (/) Its manufacturing method. Below, two preferred embodiments of the present invention are described to illustrate this. The features and effects of the invention, where * The first picture is a schematic diagram of water / oil emulsion cells. The second picture is a schematic diagram of water / oil / water emulsion cells. Manufacturing provided by the present invention The method can be used in the manufacture of agricultural chemicals. The agricultural chemicals referred to here can be divided into pesticides, herbicides and fungicides, and the pesticides include organophosphorus, carbamate, Pyrethrums; herbicides are selective 10 herbicides that are soluble in common organic solvents; fungicides include organic gases, organic phosphorus, organic ammonia, and carbamates. One of the inventions The preferred embodiment is a water-based emulsion containing pyrethrum, and its manufacturing method includes the following steps: a) Preparation of water phase Zhao: Take steaming hall water, add a small amount of defoaming agent and an appropriate amount of 15 surfactant And mixed evenly Aqueous solution mixture; b) Preparation of organic phase body: Dissolve the original organic compound containing pyrethrum in an appropriate amount of organic solvent and stir and mix well; c) Stir the water phase body and stir it. At the same time, the organic phase body is added dropwise to the water phase, so that the organic phase body and the water phase body are dispersed with each other to form 20 as an emulsion matrix of water / oil (W / 0) type cells (as shown in the first figure) D) Add a small amount of bactericide and viscous agent to the emulsion and stir it evenly; e) Stir the emulsion and slowly add distilled water. After mixing, water / oil / water ( W / 0 / W) microemulsion finished product (such as page -6- this paper size applies Chinese National Standard (CNS) Λ4 specification (210X297 mm) ^ ----— 丨 ^ -I 勹 装 丨 丨 ( Please read the notes on the back before filling in this page) Order A7 _______B7 V. Description of Invention (5 " *) as shown in the second picture). Among them, the weight ratio of the distilled water used in steps a) and e) is between 6: 4 and 9: 1, which is an appropriate ratio. In another preferred embodiment of the present invention, it is a water-based emulsion containing organic phosphorus or an ester with 5 organic compounds. The manufacturing method of these two organic compounds is basically the same as that of the previous extermination of pyrethrum water-based emulsion. The method is the same, except that when the organic phosphorus or ester water-based emulsion is made, it is added to the preparation of the organic phase, and an appropriate amount of alcohol selected from the total number of carbon atoms is between 6 and 0 As an anticoagulant, the compound is used to reduce the interfacial tension of the emulsion matrix, thereby forming water / oil emulsion microcells with fine particles of 10, so that when it is made into a water / oil / water emulsion product, it can have a good ' Physical stability. In the foregoing two preferred embodiments, the inventors made a continuous test on the separation effect, active ingredient and particle size distribution of each water-based emulsion, and the results did have better physical properties than the existing water-based emulsions. An 15 set nature. Delamination effect: Each water-based emulsion is left at room temperature, and the delamination is visually observed every other week. The results are as follows: .1 --- 1.1-\ --- 1 · ^ I— ( (Please read the precautions on the back before filling out this page). Clothing sampling time Pyrethrum organic phosphorus ester water-based emulsion water-based emulsion water-based emulsion 1 k un-layered un-layered un-layered 8 days un-layered un-layered un-layered 14 days very small amount very small amount 21 Very small amount Very small amount Very small amount 28 days Small amount small amount ~~ CNS) M specifications (210X297: :) 398182 A7 B7 V. Description of the invention (male) Approximately 1/8 total volume in 35 days Small amount approximately 1/8 in 42 days Total volume 1/7 About total volume 1/8 About total volume 1/8 49 days About total volume 1/6 About total volume 1/8 About total volume 1/6 56 days About total volume 1/6 About total volume 1 8 Approximately 1/6 of the total volume of active ingredient detection: Two parts of the finished water-based emulsion are placed at 0 ° C and 50 aC, and samples are taken every other week and tested by gas chromatography (GC). The effective ingredients, the results are as follows: Printed by the Consumer Cooperatives of the Central Bureau of Quasi-Staff of the Ministry of Economic Affairs. Sampling time Pyrethrum water-based emulsion Organic phosphorus water-based emulsion Ester-based water-based emulsion 0 ° C 50 ° C o ° c 50 ° C o ° c D〇 ° C 1 day " " ... 19. 4% 19. 2% 21. 6% 21.6% 20.6% 19. 6% 8 days 19. 0% 19. 0% 21.6% 21.8% 1 8. 0% 19. 2% 14 days 18. 4% 18. 6% 21.2% 20. 4% 19. 8% 21. 6% 21 days 18. 4% 18. 8% 20. 4% 19. 8% 19. 4% 19. 2% 28 days 18. 2% 18. 8% 19. 8 ° ί 19. 2% 18.0% 22. 4% 35 days 18. 0% 19. 0% 20. 2% 20. 0 % 20. 6% 23. 2% 42 days 18. 2% 18. 4% 20. 8% 21. 6% 21. 2% 20. 6% 49 days 20. 8% 19. 0% 19. 8% 18 8% 18. 0% 20. 0% 56 days 19. 8% 18. 2% 17. 8% 18. 2% 19. 8% 18. 4% --------- f equipment 丨-- · (Please read the notes on the back before filling this page)
J 求 5 第七夫及第三十九天，使用粒徑分析儀測量其粒徑之;》 小，結果如下： 取樣檢測時間 除蟲菊精 水基乳劑 有機磷 水基乳劑 酯類 水基乳劑 -8- 不紙张尺度適财酬家標準（CNS) A4· (21GX297公楚） 396182 A7 B7 發明説明（7) 7天 1 -3( /ζπι) 1 ~2( /zm) 1 ~2( //m) 39天 1 - 3(M m) 1 ~3( μη) 1~3(μ m) 負上係顯得相當安定’因此在其本身於靜置之時即得以避 免產生如習用技術般極易分層之不良現象’並且由於本發 明所提供之水基乳劑，其大多數之乳液微胞係呈水/油/水 型之組態，使得微胞之外層為水，因此在以水作為稀釋劑 使用時，即可快速地使該水基乳劑均勻地分散於稀釋之水 中’而且可以保持良好之分散效果，以使稀釋後之濃度維 持一適當之範圍之中’藉以避免產生如習用技術般之缺 失0 10 ^----..丨~\---叫装丨丨 (請先閱讀背面之注意事項再填寫本頁) 15 丁 、-β 經濟、部中央標隼局員工消費合作社印聚 20J Qiu 5 The 7th husband and the 39th day, use a particle size analyzer to measure the particle size; "Small, the results are as follows: Sampling detection time Pyrethrum water-based emulsion organic phosphorus water-based emulsion ester water-based emulsion -8- Non-paper scale (CNS) A4 · (21GX297) 396182 A7 B7 Description of the invention (7) 7 days 1 -3 (/ ζπι) 1 ~ 2 (/ zm) 1 ~ 2 ( // m) 39 days 1-3 (M m) 1 ~ 3 (μη) 1 ~ 3 (μ m) The negative line appears quite stable ', so it can be avoided when it is left to stand as it is used in conventional technology. The bad phenomenon of easy delamination ', and because of the water-based emulsion provided by the present invention, most of the emulsion cell lines are in a water / oil / water type configuration, so that the outer layer of the cells is water, so When used as a diluent, it can quickly disperse the water-based emulsion evenly in the diluted water, and can maintain a good dispersion effect, so that the diluted concentration can be maintained in a proper range. Missing like technology 0 10 ^ ---- .. 丨 ~ \ --- Calling equipment 丨 丨 (Please read the precautions on the back before filling this page) 15 Ding,- Ministry of Economy, the Central Bureau of standard Falcon 20 employees consumer cooperatives printed poly
(CNS ) A4規格（210X297公釐） • 9 _(CNS) A4 size (210X297mm) • 9 _