TW390815B - Apparatus and method for vapor sterilization using inorganic hydrogen peroxide complexes - Google Patents

Abstract

An apparatus and process for hydrogen peroxide vapor sterilization of medical instruments and similar devices make use of hydrogen peroxide vapor released from an inorganic hydrogen peroxide complex. The peroxide vapor can be released at room temperature and atmospheric pressure; however, the pressure used can be less than 50 torr and the temperature greater than 86 DEG C to facilitate the release of hydrogen peroxide vapor. Preferred hydrogen peroxide complexes for use in the invention include Na4P2O7.3H2O2 and KH2PO4.H2O2. The heating rate can be greater than 5DEG C. Optionally, a plasma can be used in conjunction with the vapor.

Description

Α7 Β7 Zhong Ji ’s Central Prototype and Consumer Cooperation Du Yin 轚 5. Description of the invention () Field of the invention: The present invention is more specific about a device and method for injecting bacteria such as medical devices with hydrogen peroxide vapor. In other words, this step is based on the inorganic compound of hydrogen peroxide. Explanation of related skills: Traditionally, medical equipment is sterilized by heat, such as steam, or chemical substances, such as nail or epoxy epoxy. These methods all have shortcomings. Many medical devices, such as fiber optic devices, endoscopes, tools to be plugged in, and others are sensitive to heat, moisture, or both. Both formaldehyde and ethylene oxide are toxic. Therefore, the health of medical workers is at risk. The problem caused by Huanqiu Yikeng is even more serious, because it must be r-section long time before use in order to completely remove the ethylene oxide hips from the killed object tt. Therefore, the time required for sterilization becomes very long. In addition, the use of formazan or ethoxylate is not necessary, and there must be enough water in the system. There must be sufficient concentration of the substance to be injected before the introduction of chemicals, or Water vapor and chemicals are introduced simultaneously. In addition to formaldehyde or epoxy resin, Table 1 «shows that water also plays a role when inoculated with various chemicals such as hips or steam. (Please read the “Notes on the back side of the book” and fill in this card first.) The size of the paper used in the book is selected according to the national standard of the country (CNS > A4 size (210X297 mm) A7 B7 5. Description of the invention () Table 1 The best results when talking about the effect of Hong Kong Zhan Huanyi Yikeng 25-50% Huanqiang Po slope 25-50% Ozone 75-90%

Formazan> 75% 1 glutaraldehyde 80-90% 3 Argon dioxide 60-80% 4 Methyl bromide 40-70% 1 Luprolactone &gt; 75% 1 Peracetic acid 40-80% 5 ( Please read the notes on the back./1&gt; before filling out this page) Order the Central Samples of the Ministry of Economic Affairs, Consumers and Consumers, including the printed reference of the agency: 1. Bruce, CW Gaseous Sterilization, Ann. Rev. Microbiology 15 : 245-262 (1961). 2. Janssen, DW and Schneider, PM Overview of Ethylene Oxide Alternative Sterilization Technologies, Zentralsterilisation 1: 16-32 (1993). 3. Bovallius, A. and Anas, P. surface-Decontaminating Action of Glutaraldehyde in the Gas · Aerosol Phase. Applied and Enviromental Microbiology, 129-134 (Aug. 1977). 4. Knapp, JE et al. chotine Dioxide As a Gaseous Sterilant, Medical Device &amp; Diagnostic Industry, 48-51 (Sept 1986). 5. Portner, DM and Hoffman, RK Sporicidal Effect of Peracetic Acid Vapor, Applied Microbi0 °° Sy 1785 (1968). 3 _ This paper is again used in China National Standard (CNS) Α4 size (210X297 (Mm) Shellfish in the Ministry of Economic Affairs Fei He Du printed A7 B7 V. Description of the invention () Compared with other sterilization methods, it is known that sterilization with hydrogen peroxide vapor has more advantages (see, for example, GOME Patent Nos. 4,169,123 and 4,169,124) And, as disclosed in US Patent No. 4,643,876, the combined use of argon peroxide plasma can provide some additional advantages. In this case, the argon vapour is usually from a hydrogen peroxide solution, so it can ensure that sufficient water is present in the system. From these revealed aspects and the conclusions in Table 1, it can be seen that moisture is necessary to make the plutonium peroxide vapor effective or to exhibit the maximum sterilization ability. However, there may be some problems when generating hydrogen peroxide vapor for sterilization with an aqueous hydrogen peroxide solution. At high ink levels, such as atmospheric humidity, excessive moisture in the system can cause condensation. Thus, in?丨 Before entering the hydrogen peroxide water vapor, the relative humidity of the object to be sterilized must be reduced. "Contains an area that cannot be reached by the effect of tritium powder," such as a long inner chamber. The method of sterilizing with hydrogen vapor will be a great challenge, because: 1. The vapor pressure of water is higher than that with tritium argon, so it is easier to evaporate from aqueous solution than with tritium argon. 2. The molecular weight of water is lower than that of hydrogen peroxide, so it is easier to diffuse in the vapor state than hydrogen peroxide. Therefore, when the aqueous hydrogen peroxide solution evaporates, the water will first reach the object to be exterminated at a higher concentration. Water vapour will therefore limit the diffusion of over-gasified argon in confined plaques, such as small holes or long, narrow cavities. The removal of water from the aqueous solution and the use of a relatively high concentration of vaporized hydrogen vapor will definitely cause harm to the user due to the tritium force of the solution itself. 4 This paper uses China National Standard (CNS) A4 size (210X297 mm) II--!! | —-^^ 1 11--I--m ― = 二 -I / mt (Please first Read the notes on the reverse side and fill out this page) A7 B7 V. Description of the invention () In the US Patent Nos. 4,642,165 and 4,744,951, we tried to solve this problem. In the previous patent, only a small amount of hydrogen peroxide solution was introduced to a heated surface at each time to ensure that the previous dose of hydrogen peroxide had been completely evaporated before the next dose of hydrogen peroxide solution was added. . Although this method can help eliminate the difference in vapor pressure and volatility between water and hydrogen peroxide, it does not remove the fact that water is easier to expand than hydrogen peroxide in the vapor state. In the latter patent case, a method for concentrating hydrogen peroxide from various types of dilute hydrogen peroxide and water is described, and the concentrated hydrogen peroxide vapor is introduced into a sterilized inner chamber. Question every second. This method involves evaporating and removing most of the water in the solution before injecting the concentrated peroxide vapor into a sterilized inner compartment. The weight ratio of the concentrated hydrogenated hydrogenated solution is preferably in the range of 50% to 80%. The disadvantage of this method is that the operating temperature of the solution is in a range that is harmful to humans, that is, when the concentration of hydrogen oxide is <65%, and the moisture in the vapor state is not completely removed. Since water remains in the solution, it will evaporate first, diffuse faster, and reach the object to be sterilized first. This effect is more pronounced for objects trapped in long, narrow inner chambers. A method is disclosed in U.S. Patent No. 4,943,414, that is, a container containing a small amount of liquid to be killed is communicated with the inner chamber to be sterilized, and the sterilization solution flows directly after the volatilization when the pressure drops in the sterilization cycle. Into the inner room of the object «. The advantage of this system is that the pressure difference in the inner chamber is used to pull the water and hydrogen trioxide vapor into the inner chamber, which increases the killing rate in the inner chamber. Interior room. In addition, water will also evaporate first and reach the inner chamber before the argon peroxide vapor. 5 This paper size is applicable to China National Kung Fung (CNS) Α4 size (210X297 mm). Packing (Please read the first Note: Please fill in this page again.) Order the consumption of shellfish from the Central Ministry of Economy and Trade of the People's Republic of China, including Du Yin «. A7 B7_ 5. Description of the invention () US Patent No. 5,008,106 discloses a poly-N-propylene heterocyclic compound ( An almost anhydrous complex formed by PVP) and argon peroxide to reduce the content of surface microorganisms. This complex, which exists as an extremely fine white powder, is used as an antimicrobial solution, gel, ointment and others. It can also be used in gauze, cotton balls, sponges and the like. As soon as the water on the surface containing the microorganisms comes into contact, the tritium argon is released immediately. Therefore, the sterilization effect of this method requires the presence of water. In the Ministry of Health, the rate of ΛBeigong Consumer Cooperatives (please read the precautions on the back before filling out this page). Some hydrogenated inorganic compounds have been reported. The compounds include the following categories: Some examples: test metal and ammonium hydroxide, ammonium metal oxalate, ammonium metal phosphate, acid metal pyrophosphate ft, fluoride and hydrogen halide. US Patent SU 1 68 1 860 (Nikolskaya et a 1) A method of decontaminating the surface with ammonium hydrofluoride (NH4F.H2O2), which does not necessarily reach the degree of sterility, is disclosed in the article. However, this argon peroxide ammonium fluoride inorganic compound can only A very narrow temperature range of 70-86 ^ provides surface decontamination. Even within this range, a considerable decontamination time is required, at least two hours. In addition, it is known that when the temperature exceeds 40 ° C, Ammonium fluoride will decompose into hydrofluoric acid. Due to its toxicity and reactivity, argon fluoride is not preferred in most sterilization systems. Furthermore, Nikolskaya et al. Also revealed that although at 60 * C, 90 % Of argon peroxide will be released, but at this temperature NH4F. H2〇 2 does not have the effect of decontaminating the surface. Therefore, the above-mentioned effect of decontamination of the surface seems to be achieved by the action of factors other than argon oxide. Tritium argon forms a complex with organic and inorganic compounds. The combination of these complexes is attributed to the complex compounds and the electron-rich functionalities in perfluorinated argon 6 188? ^^ (CNS) (210X2974i-i |) 'A7 B7 V. Description of the invention () The formation of hydrogen bonds. Commercial and industrial examples of such complexes are used, such as bleaching agents, decontaminants, hydrating agents in organic synthesis, and catalysts in polymerization reactions caused by free radicals. General For example, the preparation of such compounds can be achieved by crystallizing them from aqueous solutions. For example, Lu and his colleagues (J. dw. CAem. Soc. 63 (1): 1507-15 13 (1941)) borrowed The urea solution is directly added to the argon peroxide solution and crystallized under appropriate conditions to prepare a urea argon peroxide complex. U.S. Patent No. 2,986,448 describes a closed circulation system at a temperature of 0-5 eC at 50- 90% hydrogen peroxide solution to treat plutonium And sodium carbonate (Na2C03) solution for 4 to 12 hours, can prepare sodium osmium sulfonium argon oxide complex. Recently, U.S. Patent No. 3,870,783 discloses a method for mixing a cyanide solution with sodium carbonate in batch or continuous A method of inverting friction to produce a sodium carbonate hydrogen peroxide complex. The crystals are separated by filtration or centrifugation, and the solution can be used to produce more carbonate solutions. Titoval et al. K {Zhurnal Neorg. Kkim., 3 0: 2 2 2 2 · 2 2 2 7) describes the synthesis method of potassium osmate hydrogen peroxide complex (K2C03. 3H2 02), which allows potassium carbonate solids to react with argon peroxide solution at low temperature. The complex was crystallized from ethanol. These methods are very useful for the production of stable, crystal-free perfluorinated argon complex products from aqueous solutions. U.S. Patent Nos. 3,376,110 and 3,480,557 disclose a method for preparing a complex consisting of hydrogen peroxide and polyN-propylene ionocycline (PVP) in an aqueous solution. The resulting composites contain different amounts of hydrogen peroxide and a considerable amount of water. U.S. Patent No. 5,008,093 describes free-flowing, stable, almost anhydrous hydrogen hydride and poly-N-acrylic acid cyclization. M. III — I (please read the note on the back before filling this page) Order Λ Central Ministry of Economic Cooperation, ΛΛIndustry and Consumer Cooperation Du Yin «. M Ministry of Economy and Trade Standards 隼 Λ Beigong Consumer Cooperative Cooperative Printing A7 B7 V. Description of the invention (PVP) The compound composed of PVP can make the transition Hydrogen is obtained by reacting poly (N-propylene heterocyclic compound) (PVP) in ethyl acetate like an anhydrous organic solvent. Recently, U.S. Patent No. 5,077,047 describes a commercial method for making poly-N-propylene heterocyclic compounds (PVP) · perhydrogenated products, which will be divided into extremely fine 30% to 80% overgassing. Hydrogen hydride droplets were added to a PVP fluid bed maintained at 60 eC. A stable, almost water-free, free-flowing product with a tritium argon concentration of 15 · 24% was obtained. U.S. Patent No. 5,030,380 describes a method for making an electrolytic composite similar to argon peroxide to form a solid polymer. The composite is first formed in an aqueous solution and then the reactant is dried in the air or blown at low temperature. Dry to avoid thermal cracking of the product.

Titoval et. A method for producing a Na4P207 · 3H202 complex by mixing the tritium argon solution and air-drying. It has been known that this compound will partially decompose when exposed to different temperatures of 120 ° C and 140 eC for two hours. All of the methods described above for the preparation of tritium hydrogen peroxide complexes use an argon peroxide solution. Therefore, the complex is formed either in a hydrogen peroxide solution or by dropping a perylene argon solution droplet on a fluid bed containing a reactant substance. Both the vapor phase and the gas phase are well known synthetic methods. For example, U.S. Patent No. 2,812,244 discloses a method for hydrogenation in a trapped-gaseous state, thermal bag decomposition, and demethylation. Fujimoto et al. (J. Catalysis, 133: 370 · 382 (1992)) describe a method for deacidifying methanol in a gaseous state. Zellers et al. (Anal. Chem., 62: 1222- 8 This paper size is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm) ---------- 丨 | (Please read " Note on the back, please fill out this page again) Order A7 I. ______B7 _ V. Description of the invention () 1227 (1990)) discusses the reaction between styrene vapor and the flat square organic platinum compound. However, the vapor phase or gas phase reactions in these prior arts have not been used to make hydrogen peroxide composites. Summary of the purpose of the invention: Printed by the Central Ministry of Economic Affairs and the Prospective Goods Consumer Cooperatives * (Please read the notes on the back before filling out this page) One aspect of the present invention is a device for sterilizing objects with hydrogen peroxide . The device includes a container capable of holding a substance to be sterilized, and a perforated argon vapor source which is in liquid-gas equilibrium and communicates with a container. The gas source includes an inorganic compound that does not decompose to generate hydrogen peroxide from acid, and the source of steam is designed to be able to contact the object to achieve effective killing. This device can also optionally include a design that can be isolated. The tritium argon vapor source may be located in the container, or it may be in the container in the form of a plutonium and contact the container in a liquid form. If provided in the form of an enclosure, set the control in the container and enclosure. The device may include heating means for heating the trihalide inorganic compound. When the compound is in the container, a heating device can also be used to heat the container. Alternatively, when an enclosure containing rhenium hydrogen oxide complex is provided, a heating device may be used to heat the enclosure. Therefore, a preferred embodiment contains three heating devices for yttrium, which respectively add a container, a compound, and an enclosure. Another optional component of the device is a pump that can empty the container. If a box is provided, the system can be designed to empty the container and the box, and it is better to empty the individual grapefruit. Therefore, this package X can also contain two pumps, one for emptying the grapefruit and the second for emptying the enclosure. Optionally, an exhaust plutonium can also be included for container venting. If the device contains an enclosure, the first exhaust threshold can be 9 paper sizes. China National Standards (CNS) A4 specifications (210X297 mm) are printed by the Central Committee of the Ministry of Economic Affairs. A7 B7 5. Description of the invention () Exhaust the gas in the container. The second exhaust valve is independent of the first exhaust valve to exhaust the gas in the enclosure. Another optional component of this device is a mechanism that generates plasma. Plasma can be generated inside or outside the container. Many complexes are available. The complex is preferably hip-fixed. In one embodiment, the complex is a perhydrogen complex of monophosphate and condensed phosphoric acid®. In other embodiments, the complex is a hydrogen peroxide complex of acid, carbonate, osmium monosulfate, or osmium silicate. Another aspect of the present invention relates to a method for sterilizing an object with argon oxide vapor. The method includes the step of subjecting an object to contact with the hydrogenated hydrogen argon vapor released from the hydrogenated hydrogen inorganic compound to perform sterilization. The hydrogen peroxide complexes used are not explained by acids. Preferably, the composite has a water content of less than 10% and is carried out at a temperature of 25 eCtt or lower. Certain compounds may be heated during use to promote the release of vapors from the compound. For many such compounds, it is preferred to heat the desired compound to 86 ec * a. It is preferably heated at a rate of at least 5 eC / min, more preferably at a speed of at least 10, still more preferably at least 50 eC / min, and most preferably at a rate of 1000 T / min. . In one embodiment, the heating step is performed by contacting the composite with a preheated heating device. This method can be performed in the atmosphere repeatedly or below atmospheric pressure. In some embodiments, the container is evacuated before the steam is introduced into the container. If the container is empty, it is better to reduce the pressure to less than 50 torr, more preferably less than 20 torr, and most preferably less than 10 to rr. The osmium hydroxide complex can be placed in the enclosure. In this case, the pressure of the container and the enclosure can be the same or different. The emptying step is best when the container is in constant contact with this object. This paper uses the national standard (CNS) A4 specification (210X297). (Please read the precautions on the back before filling this page)

I m!-= 1-H--I---n I--II---I —1 ^-.1 I -Order ----------------- ----- A7 ________B7 V. Description of the invention () Printed by the Ministry of Economic Affairs * Consumer Cooperative Consumers' Cooperatives «. —.1 I!--Ϋ __— I- i I— I-I n I i ^ i am ^^ 1 / f \ &lt; Please read the note f on the back before filling in this page). An optional step is to generate plasma around the skull after introducing steam into the container. Plasma can be generated in the container or it can be generated outside the container and then allowed to flow into the container to surround the hips to be sterilized. Other optional steps are pressure pulsed steam applied during the contacting step, or venting to reduce the pressure below or equal to atmospheric pressure. Many kinds of inorganic compounds can be used. In a preferred embodiment, the complex used is a monophosphate a complex or a condensed phosphoric acid ft complex, such as a potassium or phosphonium salt, a magnesium salt, or a calcium salt. In this embodiment, a preferred compound is a tritiated argon compound formed with Na4P207, preferably a compound formed by two or more hydrogenated hydrogen molecules, and still more preferably Is a complex with Na4P20.7. 3H2O2. Other preferred composites are a trihalide molecule and Na3P04, Na2HP04, Na5P3104, K3P04, K4P207 (especially with two or more molecules of hydrogen gas in contact with gas), K2QP. 4, K 2 PO 4 (especially K 2 PO 4 · B 2 0 2) and Ca 2 2 0 7, M g 2 P 2 0 7. In another embodiment, the compound is a compound formed by tritium argon and oxalic acid painting. A better compound of arsenic oxalate is a compound formed by K2C2O4, especially K2C2O4.H2O2. The inorganic complex may also be a complex formed by hydrogen peroxide and carbonic acid M, such as a salt, potassium or button sinus. Preferred acid-decomposing complexes include Na2C03 (especially Na2C03.1.5H2O2), K2CO3, NaHC03, KHCO3 and Rb2C03. In another implementation tree, the complex is a complex formed by hydrogen peroxide and sinus sulfate, such as _ fishing * or _ 籯. In another embodiment, the compound is a compound formed by thorium rolled argon and thorium silicate, such as a nano-thorium. Preferred silicate complexes include Na2si03 and 11 paper paper scales, using the Chinese National Kneading Rate (CNS) of 8 and 4 grids (2 〖0'X297 mm). The central government of the Ministry of Economic Affairs has printed A7 printed by the Beigeong Consumer Cooperative. ______B7 V. Description of Invention ()

Ar2O3 complex formed by Na2Si3O7. Many of the preferred compounds, and others, release hydrogen peroxide at atmospheric pressure and room temperature. However, for some compounds, sub-atmospheric pressure is required to produce hydrogen peroxide. In another embodiment, the contacting step includes encountering argon oxide from a second source. The second source may be a second hydrogenated hydrogen compound, including an organic over-gasified argon compound. In some embodiments, the argon peroxide vapor is provided as a slurry of a hydrogen peroxide complex. The mixture may be a physical mixture or a chemical mixture, and these proper terms are defined later. A further aspect of the present invention is another method of «investing» an object with argon peroxide vapor. The method includes the step of sterilizing the substance II by exposing the substance ft to the hydrogen peroxide vapor released by heating the Na4P207 and argon oxide complex. In a preferred embodiment, the Na 4 P 2 0 7 perfluorinated argon complex is Na 4 P 2 07 3H 2 0 2. The contact can be carried out in the atmosphere, or the container can be emptied, so when the vapor enters the container, the air pressure in the container will be less than 50 torr. The compound can also be heated to about 175 ° C to effectively release steam. The contact «can be placed in a container before the contacting step. Another aspect of the present invention is «another method of sterilizing an object with rolled hydrogen vapor. This method includes placing the plutonium in a container, and then placing the plutonium compound into the container, which will not be decomposed to generate acid vapor and the "inorganic salt in contact with the material", and the container is kept below 70 eC. Static E—The time when the dog's argon vapor is released from the compound and the bacteria is effectively injected into the hip powder. The container can be any of many types of containers, including a bag, a chamber, or a house. In a preferred embodiment, the inorganic salt used is a phosphate or a condensed phosphate. In other embodiments, the inorganic ginger used is oxalate, 12 paper sizes are applicable to the National Standard for Medium and Difficulties (CNS) A4 (210X297 mm) &lt; Please read the note f on the back before filling in this Page) 'Packing. Order .. 4 Samples of the Ministry of Economic Affairs ^ Printed by Bei Gong Consumer Cooperative Association A7 B7 V. Description of the invention () Monophosphonate, monosulfate or monosilicate in some embodiments In this aspect of the present invention, the container is allowed to stand at a pressure below atmospheric pressure and below 40 X :. In some embodiments, the composite is heated to 230 eC «to promote the release of vapor. Over-rolled argon composites can be made in many types, including powders and bonds. In some embodiments, the tritium argon oxide complex is located in an enclosure. If an enclosure is provided, the enclosure may be inside or outside the container. The enclosure can be selectively separated from the container by a threshold, and in some embodiments, the container can be separated. The enclosure can also be sealed, preferably made of a gas permeable material. Better gas "translucent materials include TYVEKTM, C S R packaging and paper. An optional step is to expose the object ft to the neon slurry, and when the removable enclosure is provided, it is better to remove the enclosure from the container before making the kill. Seedling "contact with electric paddle. Another aspect of the present invention resides in a method for sterilizing an object having a shell and a narrow inner chamber with argon vapor. This method includes connecting a container containing a hydrogen peroxide compound and an inner chamber of the object II, placing the material technology in the container, evacuating the container, and then recombining the long inner chamber of the object «by the hydrogen peroxide compound Oxygen peroxide vapor released from the contents comes into contact. Perhydrogen complexes are complexes that do not decompose and release argon from acids. Any of these complexes can be used, such as phosphoric acid and condensed phosphoric acid *, sinus oxalate, osmium carbonate, mold sulphate, and silicate. It is also possible to selectively contact the outside of the skull with a sterilization system from a second source. The sterilant of the second liquid can be any of a number of suitable sterilants, such as the one placed in the container. Argon oxide, different kinds of hydrogen peroxide, hydrogen peroxide solution tt or dioxide gas placed in the container. Another optional step is to expose the object Λ waterfall to the plasma. 13 This paper uses China National Standards (CNS) Α4 specifications (210 '; &lt; 297 gong &gt; H' · ϋ_ — i ^ nu · · 11 —ϋ Ufa I a-^^ i 11 i ^ i &gt; · 11 a —.— / f., (Please read the notes on the back before filling in the book 3f) «The Central Ministry of Economic Affairs Λ Beigong Cooperative Co., Ltd. Printed A7 ____________B7_ 5. Explanation of the invention () The first circle of the mushroom description is a simple schematic circle of the steam sterilization device of the present invention. The second circle is a simple schematic circle of the steam sterilization device with an electrode in the present invention, and the electrode can be used to selectively generate a plasma. Circle 3A is a simple schematic circle of a device that can be used to heat a hydrogenated hydrogen compound. Circle 3B is a simple schematic circle of a preferred container for germicidal argon peroxide source according to the present invention. The fourth circle is a simple schematic circle that releases vaporized argon vapor from an anhydrous perfluorinated compound containing water-soluble glycerol that is unstable in the air. The fifth circle is based on the present invention. Decomposition of Decomposition Characteristics of Inorganic Complexes of Hydrogen Peroxide or Hydrogen Peroxide The simple illustration of the control system is solid. Circle 6 "shows the effect of pressure on the release of hydrogenated hydrogen from the argon argon complex caused by oxalic acid after the oxalic acid is met with a lid with a small hole. Circle 7A is a simple schematic circle according to the present invention, which is used to inject perfluorinated argon vapor into an inner chamber blower before introducing peroxide vapor. Round 7B shows the air blower in circle 7 at The schematic circle where the heating plate is in contact with the peroxide compound when the steam is introduced. The eighth circle is a simple schematic circle of the sterilization inner chamber and the heating device of the hydrogenated inorganic compound. The 9th K shows a steam kill box. Diffusion packaging of time-lapsed hydrogenated hydrogen compounds 14 This paper is again suitable for 8 Chinese standards (CNS) A4 this grid (210X297 mm) 1-I-I ..... I-m. I 1 n »I-. In Hi m. In ^ _f \ (Please read the precautions on the back before filling this page) Λ Central Ministry of Economic Affairs prints A7 ΒΊ ___ Cooperative Cooperative Fifth, 5. Description of the invention (). Lap 10: Instruction: Cover the composite with an open aluminum lid and a lid with two holes. At atmospheric pressure, it will affect K2C2 07 · H2 2 The effect of DSC curve. The 1A circle is the DSC curve of Na4P207. 2H2O2 and Na4P2 07. 3H2O2 at 760 torr. The 1st, 1B circle is Na4-20.7. 4 C 2 0 2 DSC curve at 7 6 0 to rf. The first 12 turns are Na 3 P 〇4 · 5 Η 2 〇2 at 7 6 〇t 〇rr, 7 t 〇rr and 0.3 5 torr DSC curve. The 13th circle is the DSC curve of Na2HP〇4 · 1Η2 02 and Na2HP〇4. 2 H 2 0 2 at 7 60 0 torr. The 14th circle is Na5P3 0i 2 · H2 0 2 at 760 torr. DSC curve. The 15th circle is the DSC curve of K3PO4. 3.34H2O2 at 760 torr, 7 tofr and torr. Round 16 is the DSC curve of K4P2O7. 7H2〇2 at 760 to ”and 7 10”. On the 17th lap is the DSC lifeline for K2HP〇4 · 3.15H202 at 760 torr and 1 torr. The 18th circle is the DSC curve of KH2P〇4. H2〇2 at 760 to 0. The 19th circle is the DSC curve of Na2C〇3 · 1 · 5〇2〇2 at 760 to &quot; and 7 torr. 15 (CNS ) A4 ^ * · (210X297 / ^) (Please read the notes on the back and fill in this X first)-Order, invention description () The second circle is Ca2P2 07 · 3 · 4Η2 02 at 760 Torr ( DSC curve under Τ〇ΓΓ). Figure 21 is the DSC curve of Mg2P2 07 4 · 60Η2 02 at 760 Torr and 7 Torr. Figure 22 is Na2S04.1.28H202 at DSC curve at 760 Torr. 23rd is K2S04 · .62H2〇2 DSC curve at 760 Torr "Figure 24 is Na2Si03 · 2.1 5H2〇2 at 760 Torr ( DSC curve at 1 Torr and 0.5 Torr. Figure 25 shows the DSC curve of Na2Si30.7 · 68 · 2002 at 760 Torr. Lane 1_Control Explanation room 10, 30 Objects to be sterilized 12, 56 Doors 1 6 Hydrogen peroxide source 1 8 Temperature controller 22, 46 Vacuum pump 26, 36, 122 Outlet 34 Valve 38, 43, 44 Argon peroxide enclosure 42 Net Road 52 RF Supply 54 devices 80, 125, 178 Ming Pan 90, 108, 130, 136, 184 gas permeable layer 92, 106 1 heating device 20, 49 monitor 2 4 opening 32 inlet 4 0, 4 1 electrode 5 0 Heating rectification · 9 4, 1 8 6 Ministry of Economic Affairs, Central Rubbing Bureau, Shellfish Consumption Cooperation, Duyin Oxygen A7 ___________B7 V. Description of the invention () Pyrex plate (pyre X pa 9 6, 1 8 2 Thermocouple thermometer 98 Container 99 Metal plate 1 00 Temperature monitor 101 Aluminum mesh 1 02, 1 04 Sample chamber 1 10 Heating plate 1 12 Pressure transmitter 1 1 4 Pressure gauge 1 1 6 Controller 1 1 8 Pressure control valve 1 2 0 Sterilization chamber 1 3 1, 1 70 Peroxide disk 1 3 2 Aluminum pressure plate 1 3 4 Box 1 3 8 Aluminum connection block 142 Bolt 1 44, 146, 154 '156 Seat 150 0-ring 1 48, 1 5 1 Peroxide Release chamber 1 52 channel 1 5 8 hole 1 6 0 glass-like 1 72 stainless steel blade 1 74 '176 pyrex bawl 180 electric wire 188 hot 190 high temperature adhesive tape 200 hydrogen peroxide composite powder 202 aluminum foil Layer 2 0 4 Detailed description of the present invention In the past, when hydrogen peroxide fungicides were used, it was unavoidable to use an aqueous argon peroxide solution as a fungicide. Sources. These fungicides have disadvantages caused by the presence of water in the system. At high pressures, such as atmospheric pressure, excess water in the system can cause condensation. Therefore, before the introduction of hydrogen peroxide vapor, additional steps must be taken to reduce the relative humidity of the enclosed object to an acceptable level. These bactericides also have some disadvantages caused by water, because water has a higher vapor Pressure, so in the aqueous solution is more volatile than argon peroxide, and water, because the size of this paper uses the Chinese national standard (CNS} A4 (210 X 297 mm) ---------- I ------ 1T ------ ^ ^ / ν (Please read the notes on the back before filling in this page) A7 B7 V. Description of the invention () The molecular weight is lower and it diffuses faster than argon peroxide. When a medical device or the like is enclosed in a sterilizer, the initial concentration of the germicide from the argon peroxide source is diluted when it reaches the device compared to the concentration of the hydrogen peroxide source. Used fungicides can be a hindrance to later arrivals, especially when the device to be sterilized is an object, such as an endoscope with a narrow inner cavity. Attempts have been made to use concentrated hydrogen peroxide solutions. Improve this shortcoming, the result has been proven not Satisfactory, because the solution is toxic. The present invention uses a source of thorium peroxide that contains almost no water (ie, almost anhydrous) to release almost anhydrous argon peroxide vapor, thereby overcoming the argon peroxide sterilization used in the prior art Disadvantages of the agent β In a preferred embodiment, almost anhydrous hydrogen peroxide vapor is directly generated from the almost anhydrous hydrogen peroxide composite. However, almost anhydrous argon peroxide vapor can also be generated from the aqueous composite solution ' As long as the water is removed during the evaporation process, such as under vacuum, a. Therefore, when the aqueous hydrogen peroxide composite solution is used, in the process of performing the steps of the present invention, as long as the composite aqueous solution is converted into an almost anhydrous The hydrogen oxide compound is sufficient. It is preferably 'the water content of this almost anhydrous hydrogen peroxide compound is less than 20%', more preferably the water content is not higher than i 0%, or even not higher than 5%, and the best is The moisture content is not higher than 2%. The Central Ministry of Economic Affairs, Central Rubbings Bureau, Shellfish Consumer Cooperative Du Printing Pack (please read the precautions on the back before filling this page). The preferred water content of the argon oxide composite can be seen in the 'best hydrogen peroxide composite and the generated argon peroxide vapor contains almost no moisture. However, as can be seen from the drawings, the system still has some Moisture. Some of this water may come from water and oxygen by-products generated during the decomposition of hydrogen peroxide, and some water combined with argon will react with the complex.

&lt; m, description of the invention (^ We in a series of tests, to maintain the sterilization of water at various relative humidity to test the impact of honey. Test conditions are as described in Example 1 below, will contain spores &lt; stainless steel (SS ) The blade is placed in a narrow stainless steel inner chamber of 3mm X 50cm. 0 As shown in class 0, 'In the test case, the relative humidity of 5% has no effect on the sterilization effect', but 〇% relative fishery will reduce the sterilization. Rate ^ This example shows that a small amount of water can be tolerated in a system where tf is generated from hydrogen peroxide vapor in an almost anhydrous hydrogen peroxide complex, and the effect of moisture in the system can be overcome by increasing the sterilization time. Table 2 / V Please read the lack of attention on the back before filling in this page. The diffuseness of the sterilization efficiency of the stainless steel (SS) blades located in the narrow stainless steel inner chamber of 3mm X 50cm is called the sterilization rate (positive reaction / sample suspect). , 1% R Η 5% R Η 10% 1 5 0/3 0/3 3/3 10 0/3 0/3 2/3 15 0/3 0/3 0/3 30 0/3 0/3 0 / 3 A major condition for the composition of the source of hydrogen peroxide is that its stability and argon peroxide vaporization The relationship between hair growth rate is a function of temperature and pressure. The evaporation rate of peroxide gas can be high or low. The source of peroxide can be heated or not. It depends on the parameters in the sterilization process, that is, the pressure. , Temperature, and others. Some peroxide compounds have a sufficiently high vapor pressure, so no heating is required.

, 1T Quan, · Printed paper size of Zhengong Consumer Cooperative of the Central Government Bureau of the Ministry of Economic Affairs of the People's Republic of China (CNS &gt; A4 Washer (210X297mm) A7 B7 5. The invention description () will be released A very significant amount of peroxide vapor. In general, heating the compound increases the vapor pressure of argon peroxide and accelerates the release of peroxide from the compound. To provide the required high evaporation rate, the argon peroxide source The surface area is preferably relatively large. Therefore, the source of argon peroxide can be an extremely fine powder or plated on a material with a large surface area. Of course, the safety of the material, whether it is easily available, and the price are also very important factors. Assessed by argon peroxide and urea, polypropylene &quot; I »bihalone (polyolylpyrrohydrone), nylon-6 (nylon-6) and anhydrous glycine, and ι, 3-dihydrazyl urea (1 In the case of argon peroxide released from the complex formed by 3, dimethyl urea), this 1,3-monomethyl urea peroxide complex is a liquid vessel. Compared with other complexes, anhydrous glycine Argon oxide complex in decompression ring The environment is relatively unstable, and under vacuum, most of the compounds can release hydrogen peroxide without heating. "Urea-argon peroxide compounds in the form of tablets can be obtained from Fluka Chemical Corp. (Ronkonkoma, NY), and powdered complexes are available from Aldrich Chemical Co. (Milwaukee, WI). This complex is also known as urea peroxide, peroxidation Hydrohydrogen peroxide urea complex, urea peroxide (.peroxide urea), urea peroxide adduct, peroxide peroxide adduct, spleen peroxide ( percarbamide, percarbamide perhydrate »carbamate peroxide). As used herein, the term" peroxidized feet ", including 20 _ This paper ruler has been adapted to the Ha Jiazheng Standard (CNS) A4 specification (210X297 cm) ------ ----: Installation-(Please read the note on the back of the page before filling in this page)-Order printed by the Central Quotation Leader of the Ministry of Economic Affairs of the Consumers Cooperative A7 B7 Printed by the Central Standards Bureau of the Ministry of Economic Affairs of the Consumer Cooperatives , Invention description ( All the term polypropylene is also slightly keto - argon peroxide complex (poly_ vmylpyrrolidone-hydrogen peroxide complex, PVP-H2〇2), International Patent Nos w〇 can be prepared of the method 92/17158. Or 'can also be prepared with the detailed steps disclosed below with polypropylene (PollyVinylpyrrohydrone), nylon-6 (nylon-6) and anhydrous glycine, and other organic and inorganic compounds Of the complex. Elevated temperature and / or reduced pressure can be used to promote the release of anhydrous peroxide vapor from the source and achieve an appropriate evaporation rate. Therefore, heating devices for peroxide sources and / or vacuum pumps that evacuate the sterilization chamber are preferably part of the sterilizer. Preferably, a layer of gas permeable material, such as TYVEKTM's polyethylene non-woven fabric, such as SPUNGUARDTM's polypropylene non-woven fiber 'or similar material, is used to cover the source material, allowing peroxide vapor to escape. Out without causing the hydrogen peroxide complex to escape. Hole-shaped aluminum or other suitable holes can also be used as the covering material. Figure 3A shows a device 80 for measuring the release of hydrogen peroxide from a hydrogen peroxide compound at various temperature ranges. In this device, an aluminum pan 90 is covered with a gas permeable layer 92 ', such as a medical grade TYVEKTM. The pan 90 is placed on a heating pad 94 which is located in a pyrex pan 96. A thermocouple thermometer 98 is placed 1 cm from the bottom of the name plate 90 on the outside. In a preferred embodiment, the aluminum pan 90 is open to the atmosphere, which allows the hydrogen oxalate compound to be released more in the atmosphere. 21 This paper size is in accordance with China National Standard (CNS) A4 (210X297 mm) ---------- t, ------, order ------ ^. ( (First read "Note f of the back two" and then fill out this page) Printed in the Ministry of Economic Affairs of the Provincial Bureau of Industrial and Commercial Consumer Cooperatives It 22 Α7 Β7 Jade and Invention Description (3) Circle 3B shows that it can be used to hold peroxide sources. The preferred container 99. The container 99 includes a metal plate 100, that is, an aluminum plate, optionally equipped with a heating device for heating the peroxide solids. A temperature monitor may be installed in the plate 100. 1 〇 'such as a thermometer to monitor the temperature. The peroxide complex can be placed directly on the tray 100. Alternatively, in order to uniformly heat all the peroxide composites, 'the peroxide composites may be placed on one or more layers of aluminum meshes 100, 104 between the trays 100> aluminum meshes 102, 104 Provides a large surface area and provides uniform heating when a large amount of peroxide is used. A gas permeable layer 10, such as tYVEKtm or SPUNGUARDTM, is then used to cover the peroxide compound or the net 10, 104 'so that the argon peroxide released from the compound is diffused into the sterilization chamber. Can pass through the cover 106 first. Optionally, a hole-shaped aluminum pan 1 () 8 can be added to the tYVEKtm or SPUNGUARDTM layer 106 to provide pressure and keep the composite in contact with the heating pan 100 to ensure uniform heating of the composite. The above device can provide uniform heating of the composite, and therefore can increase the amount of hydrogen peroxide vapor released from the peroxide composite. Fig. 1 is a simple schematic circle of a hydrogen peroxide vapor sterilization device in the present invention. The chamber 10 contains an object 12 to be sterilized, and is placed on a rack 14 for convenience. The chamber can be accessed through the door 16 and the optional heating device 20 has a non-aqueous argon peroxide source 18, which is controlled by a temperature controller 22. The peroxide degree is monitored by the optional monitor 24. If necessary, the chamber 10 can be evacuated by pump 26; however, the sterilization process can also be performed at atmospheric pressure. This paper ΛΑϋ 财 8Β home-made M cns) (21〇χ 丨 ------------------ Order ------ line (Please read the precautions on the back before (Fill in pages) Seal A7 B7, Shellfish Consumer Cooperatives, Central Bureau of Standards, Ministry of Economic Affairs 5. Description of the invention () The container used to hold the object to be sterilized can be a traditional sterilization chamber that has been evacuated, or a container at atmospheric pressure ( Or room) · The sterilization time depends on the nature of the object to be sterilized, the number of objects, the packaging method of the object, and the storage method in the container. Alternatively, the sterilization room itself (the entire room) can be sterilized. In either case The optimal sterilization time must be determined by experiments. In non-aqueous hydrogen peroxide operation, well-known pressure pulses can also be used to improve the penetration of antiseptic and antimicrobial properties. Examples of such pressure pulses can be combined with The methods and devices described herein are used together, as described in U.S. Patent No. 5,527,508. As described in more detail below, 'plasma can also be used to further increase activity and / or remove residues. At the end of the sterilization process Can be replaced by air exchange Excessive argon peroxide is removed from the device that has affinity for peroxide. This can be achieved by letting hot air flow into the device for a long time or evacuating. Objects that have been sterilized by argon peroxide vapor can be exposed. In the plasma to remove the residual hydrogen peroxide that may remain on Zhao. Since argon peroxide is decomposed into non-toxic products during the plasma treatment, the sterilized object can be treated without additional steps. Can be used. After the release of argon peroxide vapor, it may be necessary to separate the hydrogen peroxide source from the sterilizer to avoid resorption of the vapor, or to avoid exposure of the argon peroxide source to electropolymerization when using plasma. It is also beneficial to separate the source of hydrogen peroxide from the sterilizer when the compound used is disturbed under vacuum. The valve can be used to achieve the purpose of separation. The second one is the hydrogen peroxide of the present invention. Schematic diagram of the plasma sterilization system. It can be sterilized in the presence or absence of plasma. It can be electropolymerized to improve the argon peroxide steaming ^ ^ --- 23 S) A4 «L4M 210X297mm)----------- Gen ------ Order ------ Line.- (Please read the notes on the back before filling this page ) Printed by A7 B7___, Shellfish Consumer Cooperative of the Central Rubbing Bureau of the Ministry of Economic Affairs. 5. Description of the invention () Aerospore activity and removal of any remaining hydrogen peroxide on the object to be sterilized. Sterilization is carried out in a chamber 30, which contains a door or opening 32 into which a desired germ body can be placed. The chamber 30 includes an outlet 34 to a vacuum pump 36 through which the chamber can be evacuated. The outlet 34 includes a valve 38 that can separate the chamber from the vacuum pump 36. The chamber 30 also includes an inlet 40 connected to the enclosure 42 containing the argon peroxide compound. The inlet 40 includes a valve 44 that separates the chamber from the enclosure 42. The sterilization system also includes an inlet 42 for the enclosed enclosure 42 and a vacuum pump 36 containing a valve 43. The system can simultaneously evacuate the enclosure 42 and the chamber 30, or the enclosure 42 or the chamber 30 can be evacuated separately. The degree of vacuum is controlled by the switching of valves 38, 44, and 43. Those skilled in the art should understand that this system can also use two pumps, one for each room. The enclosure 42 may optionally be connected to a heating device 49 provided with a temperature controller 46 to control the temperature of the hydrogen peroxide compound. The vapor concentration of the hydrogen peroxide complex can be monitored by the optional peroxide monitor. The interior of the room contains a radio frequency (RF) electrode 50 connected to a suitable network 52 and a radio frequency (RF) supply 54. A convenient form of electrode is a hole-shaped cylinder that surrounds the sample and has open ends. The general implementation steps of this method are as follows: 1. An object to be sterilized 56 is placed in the chamber 30. 2. The chamber 30 may be at atmospheric pressure 'or may be evacuated to promote the penetration of hydrogen peroxide. By opening the valve 38 and the vacuum pump 36 to complete the evacuation step:. Alternatively, valves 38, 44, and / or 43 can be opened simultaneously to evacuate chamber 30 and enclosure 42. _ 24 The size of this paper is in accordance with the national standard (CNS) A4 (210X297) --- I nn I nn I— nnnn 1 ^ 1 1 nnn I ^ (Please read the note on the back ^^ (Please fill in this page again.) Printed by the Central Bureau of the Ministry of Economic Affairs, Pui Gong Consumer Cooperatives *. A7 B7 V. Description of the invention () 3. Close the valves 38 and 43 to isolate the vacuum pump 36 and the chamber 30 and the enclosure 42, and The valve 44 is opened. The argon peroxide vapor released from the hydrogen peroxide source is sent to the chamber 30 'and the release of the hydrogen peroxide vapor can be enhanced by heating. Optionally, air or inert gas can also be added. 4. Treat the object 56 to be sterilized with hydrogen peroxide vapor only during sterilization or pre-treat the object 56 to be sterilized with peroxide vapor in the chamber 30 before performing plasma treatment with sufficient horsepower. • If necessary, The chamber 30 may be evacuated at this time to promote penetration of the plasma. The time for pretreatment with electric paddles depends on the type of packaging used, the number and nature of the items to be sterilized, and the placement in the room. The best reaction conditions can be determined experimentally. 5. Expose the object 56 to be sterilized to the plasma generated by the radio frequency (RF) power supply 54 to the radio frequency (RF) electrode 50. The wireless electrical energy used to generate the plasma may be pulsed or continuous. "The object 56 to be sterilized is left in the plasma for a time sufficient to effectively sterilize and / or remove argon peroxide residue. In some preferred embodiments, the plasma time used is 5 to 30 minutes. However, the optimal reaction time should be determined experimentally. The term "plasma" mentioned in the detailed description of the present invention and the patent application patent garden includes the use of an electric field, including any possible radiation, to generate electrons, ions, free radicals, dissociation and or Any part of an atomic or molecular gas skeleton or vapor in an excited state. The electric field used covers a wide range of frequencies; however, it is usually radio waves or microwaves. The non-aqueous argon peroxide transport system disclosed in the present invention It can also be used with the plasma generated by the method described in U.S. Patent No. 4,643,876. Alternatively, it can also be used with U.S. Patent No. 5, η5,166 or ____25. Feng (CNS) A4 ^ (21 () χ297 public shame)--(Please read the note f on the back before filling in this card)

.IT A7 _B7 __ V. Invention description () No. 5,087,418 is used together with the electropolymer produced by the method described above. The above device is particularly advantageous for the use of unstable hydrogen peroxide compounds under vacuum. There are at least two methods that can be used to reduce the loss of hydrogen peroxide during vacuum. First, evacuate the small sterilization chamber separately. Second, if the sterilization chamber used is small enough, there is no need to evacuate the small sterilization chamber at all. Glycine anhydrous peroxide belongs to this unstable non-aqueous hydrogen peroxide complex. Under vacuum, this compound releases argon peroxide vapor. Figure 4 shows the release of hydrogen peroxide vapor from glycine anhydrous peroxide under vacuum. The procedure used to release hydrogen peroxide vapor from glycine anhydrous peroxide is as follows: (1) Valves 43 and 44 are closed while the chamber 30 is evacuated. (2) When the chamber containing the hydrogen peroxide compound 42 is evacuated, the valves 38 and 44 are closed and the valve 43 is opened. (3) Close the valve 43 and open the valve 44 so that the hydrogen peroxide vapor can diffuse into the chamber 30. As shown in the figure, under reduced pressure, 'even without an additional heating step, hydrogen peroxide vapor will be released from the composite.' Increase the release of peroxide vapor. Therefore, even an unstable hydrogen peroxide complex is useful in the sterilization method of the present invention. Compared with the previously proposed argon peroxide sterilization method, the present invention can provide at least four additional advantages: 1. Overcoming the disadvantages of using a concentrated argon peroxide solution which may be toxic. 2. To overcome the disadvantage that the relative humidity of the surface to be sterilized must be reduced in advance to avoid condensation.

Central Government Bureau of the Ministry of Economic Affairs, Shellfish Consumer Cooperative Seal A7 ____________B7_ V. Description of the Invention () 3. The system no longer needs the existence of water, so when water diffuses into the narrow inner chamber, 'water and hydrogen peroxide vapor no longer need to compete. . 4. No special container is needed to send sterilizing vapor into the narrow inner chamber. The achievement of effective sterilization with hydrogen peroxide vapor in almost anhydrous conditions is the most surprising discovery of the present invention. Previous techniques have shown that in the process of sterilizing with chemical gas or steam, the existence of moisture is required to achieve the purpose of sterilization. The advantage of the present invention is that the water is almost completely excluded from the system, and a more rapid and effective sterilization is obtained. The measured sterilization efficiency of various non-aqueous hydrogen peroxide compounds is described in Examples 1 to 4 below.籯 Example 1 The bactericidal efficiency data are based on the hydrogen peroxide vapor released from the almost anhydrous urea peroxide compound against the Bacillus subtilis spores (5 &lt; aci // in the plastic inner chamber of metal and TeflonTM) released from the almost anhydrous urea peroxide compound. wj να / ... fnfgerj) is obtained by sterilization. A. Measurement step 1. The instrument is shown in Figure 3A. 'Fluka Chemical C or ρ. (R ο nk ο nkoma, NY) 4 grams of peroxide peroxide urea tablets are crushed and placed on an aluminum plate. 90 on. The disc 90 is covered with a layer of medical-grade TYVEKTM (elongated polyethylene fiber that allows breathing) to release hydrogen peroxide vapor from the composite. * This layer must be passed through before spreading into the sterilization chamber. Place the aluminum pan 90 in the aluminum sterilization chamber (see section 1 _) at the bottom of a pyrex dish 96 ./—Λ, please read the note on the back before filling this page) Order

Du Yin 轚 A7 _______B7_ of the Ministry of Economic Affairs, Consumer Consumption Cooperation of Employees V. The heating pad 94 in the description of the invention (). The sterilization chamber, with a volume of about 134 liters, contains: a hydrogen peroxide monitor capable of measuring the concentration of argon peroxide in the vapor phase. A temperature controller that can control the temperature of the heating pad. • An injection port capable of injecting argon peroxide liquid into the sterilization chamber. • A metal rack that can hold the plastic disc with the inner chamber device for testing. • A resistance heater located at the exterior wall of the sterilization chamber to maintain a sterilization temperature of 45 t during the efficiency test. 2. Biological test and challenge In order to evaluate the efficiency of the non-aqueous solution peroxide delivery system, stainless steel blades containing 1.04 X 106 bacillus subtilis spores were made from 3mm inner diameter x 40cm long and 3mm inner diameter X at the same distance. 50cm long and 1mm inner diameter X 50cm long stainless steel inner chambers are arranged at both ends and bottoms. These inner diameters and lengths are often used in the inner chambers of medical appliances. The size of the compartment where the biological test sample is located in each inner chamber is 13mm inner diameter X 7.6cm long. The biological test was performed with a metal inner chamber. A total of 9 inner chambers were evaluated in each test. Includes 3 different inner diameter and length combinations, each with 3 inner chambers. A long piece of paper (6mm x 4mm Whatman No. 1 color analysis analysis paper) containing 4.1 X 106 bacillus subtilis spores (5acH / U) S v ar be r)) was placed on an inner diameter of 1 mm x a length of 1 mm and an inner diameter of 1 mm x 2m long '1mm inner diameter x 3m long, and 1mm inner diameter x 4m long Teflon (TM) inner chamber bottom for similar experiments. The size of the compartment in which the biological test samples are located in the center of the inner chamber is 15 mm in inner diameter x 7.6 cm long. Teflon (TEFLONTM) internal test biological test, each test ---- _28__ This paper is applicable to China National Standard (CNS) A4 «UM 210X297 mm) one by one (please read the notes on the back first) Please fill in this page again for the matters} ·-*? Τ Central Government Bureau of the Ministry of Economic Affairs, Shellfish Consumer Cooperation Du printed A7 ------------- _B7 V. Description of the invention () A total of 12 The chamber includes three different inner diameter and length combinations, each of which has four inner chambers. The inner chamber containing the biological test sample is placed on a plastic tray, and the entire plastic tray is placed on the rack of the sterilization chamber. .Close the door of the sterilization chamber and vacuum sterilize to a pressure of 0 2 Torr (Torr) with a vacuum pump. Heat the aluminum pan containing the argon peroxide urea adduct to 80_8lt for 5 minutes to the bottom of the pan. A thermocouple thermometer on the side wall of an aluminum plate of about 1 cm measures the temperature. During this period, it can be known from the peroxide monitor that the hydrogen peroxide concentration in the sterilization chamber has increased to 6 mg / L. Expose the biological test samples to peroxide respectively. After 5, 10, 15 '20' and 25 minutes under hydrogen vapor, the biological test sample was moved to the containing 277 The unit catalyzes every 15 ml of trypticase soy broth to 'neutralize any residual hydrogen peroxide vapor on the test sample. All samples were incubated at 32. (: 7 days and observed bacteria The growth situation. For comparison, '50% hydrogen peroxide solution was also injected into the sterilization chamber and allowed to evaporate from the surface of the heated syringe (a heated metal table). The concentration of hydrogen peroxide in the gas phase is 6 mg / L. The test chamber used in these test and biological test samples is the same as that used in the non-aqueous argon peroxide complex test. It was exposed to argon peroxide After the steps, the method of processing biological test samples is also the same. 测 弑 结 旲 29 The paper size of the table applies to the Chinese national standard (CNS &gt; Ai size (210X297 mm)) (Please read the precautions on the back before filling in this Page) _, loading, ordering, printing, printing, A7, Zhengong Consumer Cooperative, Central Bureau of the Ministry of Economic Affairs _____B7 V. Description of the invention ()-Testing performed in the stainless steel and TeflonTM inner chamber The results are shown in Tables 3 and 4, respectively, and the effect of the non-aqueous over-gasification argon delivery system on the two metal and non-metal inner chambers can be seen. In the non-aqueous solution with the smallest inner diameter and the longest inner chamber evaluated The complete hydrogen peroxide delivery system can achieve the effect of completely killing the bacterial spores within 5 minutes. At the same time, in a system that diffuses with a 50% argon peroxide aqueous solution ', the complete killing of bacteria cannot be achieved even after 25 minutes "Spores" 袅 3 Comparison of sterilization efficiency of aqueous / non-aqueous solution. The sterilization result of stainless steel blade in stainless steel inner chamber_ (positive reaction / number of samples) peroxide diffusion time 3mm X 3mm χ 1mm x source (minutes) 4 0cm 5 0 cm 5 0cm 5 3/3 3/3 3/3 10 0/3 2/3 3/3 5 0% solution 15 1/3 1/3 1/3 20 0/3 0/3 1/3 25 0/3 0/3 1/3 5 0/3 0/3 0/3 10 0/3 0/3 0/3 Peroxide will be 15 0/3 0/3 0/3 20 0/3 0/3 0/3 25 0/3 0/3 0/3 ------ 30 This paper uses Chinese National Standards (CNS) A45 ^. (21〇x297 ^ a) (Please read note f on the back before filling in this Page),? Τ A7 B7 V. Description of the invention () * 4 Aqueous / non-aqueous Comparison of sterilization efficiency 6mm X 4mm paper sheet sterilization force results in TeflonTM (positive reaction / number of samples) peroxide diffusion time 1 mm X 1 mm x 1mm source (min) lm 2 m 3 m 5 3 / 3 3/3 3/3 10 3/3 3/3 3/3 50% solution 15 0/3 1/3 1/3 20 0/3 0/3 0/3 25 0/3 0/3 0 / 3 5 0/3 0/3 0/3 10 0/3 0/3 0/3 Urea peroxide 15 0/3 0/3 0/3 20 0/3 0/3 0/3 25 0/3 0 / 3 0/3 mm 4m 3/3 3/3 2/3 1/3 U3 0/3 0/3 0/3 0/3 0/3

X / 1 · (please read the note f on the back before filling in the original text) Ordering by the Ministry of Economic Affairs of the Ministry of Justice, Shellfish Consumer Cooperatives, India, 31. Usually used in a variety of chemical gases other than hydrogen peroxide fungicides In the process of sterilization / steam, water is always present, so the fact that rapid sterilization can be violated in almost anhydrous conditions is quite unexpected. Because the argon peroxide vapor phase sterilization system uses an argon peroxide aqueous solution, there is also the presence of water in those systems. To test the sterilization efficiency of various other peroxide compounds, this paper uses the national sample of China. Vehicle (CNS) A4 specification (21 × 297 mm) A7 _____B7 __ V. Experiments under the description of the invention () Example 2J and 4 The equipment of Example 1 was used to test the polyproporoxolone · argon peroxide compound (Example 2) Sterilization efficiency of 'nylon 6-argon peroxide complex (Example 3) and 1,3-dimethyl urea hydrogen peroxide complex (Example 4). These compounds were synthesized as described in Examples 12 and 13 below. The test parameters are as follows: Example 2 Example 3 MlM 4 Temperature of the sterilization chamber 4 5 ° 〇4 5〇C 4 5t Initial pressure 0.2 Torr 1.0 Torr 1.0 Torr Peroxide weight 17% 10.5% 2 6.6% Percent peroxide concentration 6mg / L 6mg / L 6mg / L 8g 18g 6g oxide weight used per cycle releases peroxide 1 1 oec no ° c 80 ° C temperature cracked by the Ministry of Economic Affairs Central Central Standards Bureau negative labor cost cooperative mm (Please read the precautions on the back before filling this page) In each case, the bacterial spores are located in a plastic inner chamber of 6mm x 4 pieces of paper and a stainless steel blade in a stainless copper inner chamber. The results of β sterilization efficiency are shown in Table 5 below. . The property of this paper is BCN (A4% #) &lt; 210X2! ^ # 5. Description of the invention (A7 B7 Polypropyrrolidinone, Nylon 6, and〗 3_ Dimethyl urea and hydrogen peroxide Result of sterilization efficiency and sterilization power of the formed compound (positive reaction / number of samples) _ψexposure within 5 minutes chamber type inner chamber size example 2 example 3 example 4 1mm X 1 m 0/3 0/3 0/3-1mm X 2m 0/3 0/3 0/3 TeflonTM 1mm X 3m 0/3 0/3 0/3 1mm X 4 m 0/3 0/3 0/3 3mm X 4 0cm 0/3 0/3 0 / 3 Stainless steel 3mm X 5 0cm 0/3 0/3 0/3 1mm X 5 0cm 0/3 0/3 0/3 Printed by Zhengong Consumer Cooperative, Central Bureau of Economic Affairs, Ministry of Economic Affairs «. Table 5 shows that only 5 points are required The exposure time of radon, the peroxide vapor generated by each of the hydrogen peroxide compounds tested is sufficient to provide effective sterilization. The temperatures listed above for the release of hydrogen peroxide vapor from peroxide solids are based on The outside of the tray is measured by a thief thermometer located 1 cm from the bottom. As described in Example 5 below, further measurements are made with a thermometer located at the bottom of the inner tray, such as a fluorine thermometer, 'the temperature at the bottom of the tray is about higher 3〇_ 35 ° C. Therefore, in the previous example, when the temperature measured by the thermal radon thermometer is 80 ° C, the temperature at the bottom of the pan should be about 110-115 ° C, and when the temperature measured by the thermal radon thermometer is 1 1 0 eC, The temperature at the bottom of the pan should be about 1 40-1 4 5. (: aa.) The paper size of the table applies to the Chinese National Standard (CNS) Λ4 specification (21 OX297). ----- ^ ------ (锖 Read the sobbing items on the back of the nose first ^^ The central government of the Ministry of Economic Affairs f 准 ΗConsumer cooperation Du printed A7 __________ 5. Description of the invention () 篪 Example 5 will be a A fluorine thermometer is attached to the bottom of the aluminum pan to measure the temperature of the bottom of the aluminum pan containing the solids of the peroxide compound. An OmegaTM thermometer (OmegaTM) is placed on the outside of the aluminum pan from the bottom 1cm from the bottom. Record the two thermometers. Difference. Each time the aluminum pan is heated to the temperature indicated by the pan-side thermometer, let it cool down and then re-heat to the required temperature. The recorded temperature is as follows: C, the first time, the second time and the third time, the average is 8 0 eC 110.9 110.6 110.6 110. 100 ° C 13 1.5 132.6 132.0 132. The outside temperature display thermometer higher thermal coupling about 3〇-35〇C. Further tests are more open (no internal chamber) system data from the obtained aqueous and non-aqueous source of peroxide type of sterilization efficiency. The experimental steps are detailed below. Example 6 Use the device of Example 1 to seal in a TYVEKTM / mYLARTM envelope, 6mm X 4mm containing 6.8 X 105 Bacillus subtilis var. Of Whatman # 1 paper. (TYVEKTM is a kind of breathable cellulose paper ΛΑϋ made of polyethylene. It is tBI8 (CNS) 44 secret (21Gx29371 mm) ~~ -------------- --ίτ ------ ^ (Please read the notes on the back before filling out this page) V. Description of the invention () A7 B7 Printed by the Central Government Bureau of the Ministry of Economy Ester impermeable substances). The pieces of paper to be subjected to the biological test were respectively placed in the middle and back of the front end 'of a polyphenylene oxide disk containing an adjustable fiberscope. Place the tray in a polyphenylene oxide container with an air vent above the container and two at the bottom to facilitate diffusion. A four-diameter port is covered with a breathable polypropylene package (SPUNGUARDTM Resterilize the envelope (Kimberly-Clark, Dallas, TX) to keep the contents of the container sterile after the sterilization process. Place the container in the apparatus of Example 1 and reduce the pressure in the sterilization chamber to 0.2 Torr. An aluminum pan containing 2 g of hydrogen peroxide urea adduct (Fluka Chemical corp.) Was heated at 80-81 eC for 5 minutes to provide 3 mg / L of hydrogen peroxide vapor in a sterilization chamber, and an aluminum pan about lcin from the bottom of the pan Thermocouple thermometer on the side wall to measure temperature. The biological test sample was exposed to rhenium peroxide vapor for 5 and 10 minutes. After the vapor exposure, all biological test samples were processed using the procedure of Example 1. For comparison, a 50% aqueous hydrogen peroxide solution was also injected into the sterilization chamber and allowed to evaporate from the heated syringe. The concentration of argon peroxide in the gas phase produced by the injection of the volume of the argon peroxide solution was 3 mg / L. The configuration of the test, the composition of the biological test sample, and the treatment method after the biological test sample is exposed to argon peroxide are the same as those used for the non-aqueous nitrogen peroxide test. The test results are shown in Table 6. (Please read the notes on the back before filling in this page) € This paper size is in accordance with Chinese National Standards (CNS &gt; A4 size (210X297 mm)) Printed by the Central Ministry of Economic Affairs of the Ministry of Economic Affairs and Consumer Cooperatives A_ __ __B7 5 、 Explanation of the invention () 袅 6 Water-labeled non-water-concentrated in the open system The &lt; &gt; Anthracitic rate without internal chamber measurement, peroxide source diffusion time (minutes), sterilization result (positive reaction / total number of samples) 5 0 % Solution 5 3/3 10 3/3 per 5 1/3 10 0/3 The test results show that in the open system, that is, the biological test sample is not placed in an internal chamber, compared with the aqueous solution type argon peroxide. The compound, non-aqueous solution type has greater sterilization efficiency. Once again, it was unexpectedly discovered that even without the need to allow argon peroxide vapor to diffuse into a narrow inner chamber, the non-aqueous type system can still provide better This implies that the mode of action of hydrogen peroxide is not the same in systems with or without water. To determine the sterilization efficiency of non-aqueous peroxide vapor under normal and non-decompression conditions, the following was performed test The test conditions are detailed in the following β. Example 7 The sterilization efficiency test was performed in an open system by argon peroxide vapor released from each compound at atmospheric pressure under atmospheric pressure. In this test, it will contain 1.04 X ΐ〇 ό Bacillus subtilis spore ^ "z" ger)) The remaining steel blade is sealed in a TYVEKTM / MYLARTM letter paper used in China (21〇χ J76mm)----- -------------- Order Z8I. · {Please read the notes on the back before filling in this page} Α7 Β7 V. Description of the invention () Sealed. The blade for biological test will be set At the front, middle, and back of the polyphenylene oxide disk. Place the disk in the device of Fan W1 and close the door of the sterilization chamber. During the test, aluminum containing 4 g of the peroxide gas urea adduct (Fiuka chemical Coorp) was used. Pan heated to 80-8lt: Measure the temperature with a thermocouple thermometer on the side wall of the aluminum pan about 1 cm from the bottom of the pan. Expose the biological test sample to hydrogen peroxide vapor 5, 10, 20, and 30. Min. After the vapor exposure, all biological test samples were processed in the same way as in Example 丨 Table 7 shows these test results and Sterilization efficiency of solution type peroxide in open system under the atmosphere. Table 7 Sterilization efficiency of non-aqueous type peroxide in open system under atmospheric pressure (Please read the precautions on the back before filling this page) Order Ministry of Economic Affairs_ Printed by the Central Government Bureau of Labor and Consumer Cooperatives «. Peroxide diffusion time Source of sterilization results (minutes) (Positive reaction / total number of samples) Peroxide per 5 3/3 10 1/3 20 0/3 3 0 0/3 is The amount of peroxide released from the argon peroxide urea complex at various temperatures was measured, and the following further tests were performed. The test conditions are detailed in Example 8. The size of this paper is in accordance with China National Standards (CNS) A4 specification (210X297 mm) A7 --- _____ B7 V. Description of the invention () 簏 Example 8 The commercial medicine is crushed to get over (Fluka chemical Corp.) Each powder was oxidized and placed between two 12.7 cm x 12.7 cm inscribed meshes in the 3B 囷 device. The aluminum pan was then heated and the temperature was monitored with a thermometer located at a corner of the aluminum pan. Table 8 shows the approximate percentages of peroxide released after 5 minutes of heating at various temperatures. Data show that 100 ° C releases peroxide from the compound at 140 ° C. The lower percentage of peroxide released at lower temperatures. Clip 8 Release of non-aqueous peroxide at various temperatures (please read the precautions on the back before filling out this page) The released gaseous lily ratio 8 0 ° C ～ 2 5% loot ～ 6 5 0 / 〇1 20 ° c ~ 80% 13 0 ° C -90% 140 ° C ~ 100% 〇 / 〇- 泉 'Central Ministry of Economic Affairs Zhun ΛPei Gong Consumer Cooperative Co., Ltd. printed peroxide compound can be in the room The release of hydrogen peroxide vapor at mild atmospheric pressure, such as per-peroxide complex, can be effectively used in a variety of sterilization applications. The compound of the present invention can be used not only in the above-mentioned sterilizing device of the present invention, but also as a part of a self-service sterilizing packaging material, or coated on a support such as gauze, sponge, cotton, and the like. This compound can be used to sterilize packaged substances at room temperature or high temperature. For packaged medical __ _____22___ ^ Paper size is applicable to China National Standard (CNS) A4 specification (210X297 mm) A7 -__ B7__ V. Description of the invention () Sterilization of therapeutic or surgical products is particularly useful. Some specific uses of the compounds of the present invention are detailed in the following examples. The peroxide complexes used in the following examples are tablets of peroxide type (Fluka chemical Corp.) or powders obtained by crushing the bond. Example 9 A self-service sterilization bag was assembled in the following manner: A stainless steel blade containing 3 8 X 105 bacillus subtilis spores να, · • e / ^) on a surface was placed on a sterilized petri dish. Put the cultured blood together with the lg drug bond type or the powder type peroxidation compound into a larger petri dish. After that, put the larger petri dish into the TYVEKTM / mylarTM (breathable, Table 9), M YLARTM / m YLARTM (air-tight, table 10) or paper / MYLARTM (air-permeable 'table 10) in a sterilization bag β and then sealing the sterilization bag》 Expose each sterilization bag at different temperatures for different times, as follows Shown in Tables 9 and 10. The method of Example 1 was used to evaluate the bactericidal effect on biological test samples. The results are shown in Tables 9 and 10. The "+" sign indicates the growth of bacteria 0. (Please read the precautions on the back before filling in this page.) Gas booking, the print rate of the Central Laboratories Bureau of the Ministry of Carp, Printing and Cooperative For domestic use, IA 22 ¥ Public 7 29 A7 B7 V. Description of the invention () 袅 9 Self-killing anti-theft bag temperature theft type (TYVEKTM / MYLARTM) Peroxide type 1 hour 2 hours 3 hours 4 hours 2 3 ° C Powder Ten---Tablets + +--4 0 ° C Powder---Tablets----60 ° C Powder---Tablets-(Please read the note on the back side before filling in This page) Binding * Order Table 10 lists the results of the sterilization efficiency of self-service sterilization bags with (paper / MYLARTM) and without (MYLARTM / MYLARtm) breathable barriers. The sterilization bag is assembled by the above method, but only powdered peroxide is used as a source of peroxide vapor.袅 10 Self-help sterilization with or without breathable obstruction 4K temperature encapsulation type 2 hours 4 hours 2 3 t M YLAR / MYLAR-• Paper / MYLAR + 4 0 ° CM YLAR / MYLAR • Paper / MYLAR • 6 0eC M YLAR / MYLAR • Paper / MYLAR-^ Using the National Standard for Difficulties (CNS) A4 (210X297 mm) Printed by the Central Government Bureau of the Ministry of Economic Affairs A7 _____ _ B7 V. Description of the invention ()-The test results show that it is contained in self-service sterilization bags with and without breathable obstructions (per compound of the present invention can be peroxidized in just 2 to 3 hours, No moisture, effective sterilization of the objects in the sterilization bag at room temperature and atmospheric pressure. To determine the sterilization efficiency of the sterilization system of the present invention in a closed container, the following experiments were performed. Example 10 The following is a self-service sterilization container. Way to assemble: a stainless steel blade containing 3 8 X 105 (Table 11) or 9.2 X 105 (Table 12) Bacillus subtilis spores (5aci // i / j ίΜδίίΠί (ναΓ)) on the surface, put 20 holes (size 3/16 inch) inside a small polyethylene (PE) tube. This tube is then placed in a larger polyethylene (pE) tube 'with an airtight cover' or a layer of breathable SPUNGUARD® ( CSR film) to cover. In this larger polyethylene (pE) tube, there is a second polyethylene (PE) tube. It also has 20 holes on its surface (3/16 inch) This tube contains lg of peroxidized powder or tablets, and is sealed in SPUNGUARD ® (CSR film) or TYVEKTM bag. Each container is exposed to different temperatures at different times, as shown in the following table and 12 The method of Example 1 was used to evaluate the germicidal effect on the biological test samples. The results are shown in Tables 11 and 12. The "+" sign indicates the growth of bacteria. __ 11_ This paper standard is applicable to China National Standards (CNS) Α4 ^ Grid (2 丨 0X297mm) (Please read the note on the back before filling this page), 1Τ

&gt; · ^ I Printed by the Consumer Cooperatives of the Central Bureau of Standards of the Ministry of Economic Affairs A7 B7 V. Description of Invention ()

Table UL Self-service sterilization container without breathable window Temperature sealed type 2 hours 6 hours 2 3 ° C Unpacked tablets +-C / C * Packed tablets +-C / C * Packed powder +-4 0 ° C Not Packaged tablets--C / C packaged tablets C / C packaged powder--60 ° C Unpackaged tablets--C / C packaged tablets--c / C packaged powder sleep-*-made by CSR film Chengzhi bag (please read the note on the back before filling this page)

、 1T &quot;. '! 42 This paper size applies to Chinese National Standards (CNS) Α4 grid (210 × 297 mm) Printed by the Shell Consumer Cooperative of the Central Samples Bureau of the Ministry of Economic Affairs A7 B7 5. Description of Invention

Ml 12 Self-service sterilization container without air-permeable CSR window. Temperature packaging type 0.5 hours 1.0 hours 1.5 hours 2.0 hours 3.0 hours 4.0 hours 2 3 ° C Unpackaged tablets + + +-. Unpackaged powder + + +. T / T * packaged tablets + + + + T / T packaged powder + +---C / C * * packaged tablets + +---C / C packaged powder + +.. 4 0 ° C Unpacked tablets. Unpacked powders... T / T * packaged tablets +-. T / T packaged tablets •-•. C / C packaged tablets----C / C packaged powders--_- 6 0 ° C Unpackaged tablets--㈣-Unpackaged powders----T / T packaged tablets..---T / T packaged powders • •.. C / C packaged tablets... C / C Packaging powder----*-Bag made of TY VEKTM * *-Bag made of CSR film ^ 1.-----------I--—— \. ^ I …… ------ T *, vs / —λ (Please read the notes on the back before filling in this page) 43 This paper size applies to China National Standard (CNS) A4 specification (210X297 mm) A7 B7 Printed by Shelley Consumer Cooperative of Central Bureau of the Ministry of Economic Affairs V. Description of the invention (These test results show that the non-aqueous peroxide-containing compound in a container with or without a breathable obstruction can provide effective sterilization within 3 to 4 hours at room temperature. It can provide effective sterilization in only half an hour at temperature. It is known that the peroxide vapor released from the #water solution type peroxide compound is very effective for sterilization at room temperature. If it is at high temperature, The effect is better. This kind of compound can be placed in a sterilization bag 'container, sterilization room, room or any area that can be sealed, so that the released peroxide vapor can effectively sterilize the object. The compound can be heated In order to promote the release of steam and enable it to complete sterilization in a short time at room temperature. Therefore, the compound of the present invention is very useful for many applications requiring sterilization. As long as the compound is placed in a closed area containing an object to be sterilized, that is, The sterilization step can be completed ^ Different from the method used in the prior art, no contact with water is required to provide activated hydrogen peroxide. To determine that non-aqueous peroxygen can be effectively used The compound complex achieves the purpose of sterilization under low pressure for a short time, and the following experiments have been performed. 簏》] 11 A self-service sterilization container was assembled in the following manner: The surface contained 9 2 X 105 bacillus subtilis spores (5aciiiui The non-recorded steel support is placed inside a small polyethylene (PE) tube with 20 holes (3/16 inches in size) on one surface. This tube is then placed in a larger polyethylene (PE) tube, covered with a breathable lid, or a wide CSR envelope (SPUNGUARDTM). Among the larger polyethylene pipes, there is also a second polyethylene pipe, and its surface is also 44 paper sizes common to Chinese national standards (CNS &gt; A4 size (210X297 mm) I ^ 1 丨 — I ^ I — — I — line — if, (please read the note on the back before filling in this page) A7 _B7____ 5. Description of the invention () There are 20 holes (the size is 3/16 inches) ). This tube contains lg of peroxide per powder or tablet and is sealed in a CSR envelope or TYVEKTM bag. Place the large tube in a sterilization chamber with a volume of 4.5L or 173L. Let each container under pressure 1〇 〇 Torr and 23 eC exposure for 2 hours, as shown in Table 13 below. The method of Example 1 was used to evaluate the sterilization effect on biological test samples. The results are shown in Table 13. 袅 13 Self-help with a breathable window under reduced pressure Macro Seed Killer (Please read the precautions on the back before filling out this page) Temperature-sealed 4.5L sterilization chamber 1 73 L sterilization chamber 2 3 ° C Unpackaged powder-T / T packaging powder-C / C packaging Medicinal tablets • Ordered by the Central Standards Bureau of the Ministry of Economic Affairs, Zhengong Consumer Cooperative, printed results showing self-help with breathable obstructions The sterilization container can provide effective sterilization within 2 hours at room temperature of 100 Torr. When compared with the results in Table 12, these results show that the peroxide compound of the present invention is compared with the time required for sterilization at atmospheric pressure. The compound can achieve sterilization in a short time under reduced pressure. Therefore, the invented argon peroxide complex compound can provide a significant sterilization effect in a short time. In addition, 'as discussed above, it can be improved by electric equipment. The germicidal activity of hydrogen peroxide vapor. After exposure to argon peroxide vapor, contact the material to be sterilized with the plasma for a period of time that is sufficient to complete sterilization. 45 This paper size applies to the Chinese family standard (CNS) A4 specification (210X297) (Mm) 5. Description of the invention () The object that has been sterilized with hydrogen peroxide vapor can be exposed to the plasma again to remove the residual hydrogen peroxide on the object. The residual hydrogen peroxide will decompose when treated with the plasma. It is a non-toxic product, so the germicidal substance can be used without any additional steps after processing. Non-aqueous peroxide compound is used for many sterilizing applications. Often useful, including part of a self-service sterilization package. In addition, the compound can also be used in many methods to sterilize objects with steam, for example, the method described in U.S. Patent No. 4,943,4 ^ this patent The case discloses a method that includes a container whose inner chamber contains a small amount of a volatile sterilization solution liquid. When the pressure decreases during the sterilization cycle, the sterilization liquid will flow directly to the object in the inner chamber to be sterilized. The method disclosed in this patent is modified to use a non-aqueous peroxide. The compound is placed in a container and connected to the inner chamber containing the object to be sterilized, and the object is then placed in the container and evacuated. The inside and outside of the object can come into contact with the peroxide vapor released from the non-aqueous compound. The plasma can be selectively generated and used to enhance sterilization and / or remove residual hydrogen peroxide from objects. The use of the above-mentioned non-aqueous type peroxide compound in the system can overcome the shortcomings of rapid evaporation of water in the aqueous solution and grab the inner chamber before the hydrogen peroxide vapor β. Therefore, more effective sterilization can be achieved in a shorter time. Hydrogen peroxide compounds, such as anhydrous glycine, are particularly advantageous because they can release a significant amount of hydrogen peroxide vapor for sterilization without the need to heat the compound under reduced pressure. The cost of the IL 丞 solution type supergasification box tablet compound was further invented to provide a non-aqueous solution type hydrogen peroxide complex printed by the Shell Standard Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs «. A 7 _____B7 V. Description of the invention () Method 'The non-aqueous hydrogen peroxide complex can be used as a source of the above-mentioned hydrogen peroxide vapor germicide or as part of a self-service sterilization package. Of course, the hydrogen peroxide complex can also be used in other applications, such as bleach, contact lens solutions, catalysts, and other applications well known to those skilled in the art. The general preparation method of the non-aqueous-type hydrogen peroxide complex of the present invention is as follows: (η Chiang reactant is placed in the killing mysterious substance and reacts with hydrogen peroxide may be a solid in various forms (for example, powder, crystal, film Among other things, it is preferable to have a high surface area to improve the reaction rate.) After the decompression of the sterilization chamber, if there is sufficient time for the solvent to evaporate, the reactant substance may also be a solution dissolved in water or other solutes. Substance It can also be a liquid with a higher boiling point (150 ° c) than hydrogen peroxide. Because the reaction rate is faster at high temperatures, it is better to start the sterilization chamber before or after introducing the reactants. However, the temperature must not be too high for the reaction The product is boiled or volatilized. The reactant can be placed in any container that can contact the peroxide vapor. If it is in powder or other form, when the sterilization chamber is evacuated, it may be blown away. In a vented container, the hydrogen peroxide vapor can diffuse into the container. F 2 1 Evacuation of the sterilization chamber In some embodiments, the sterilization chamber is evacuated to less than Air pressure conditions, for example, lower than the argon peroxide vapor pressure (depending on its concentration and temperature) to ensure that all peroxides are in a vapor state. The vapor pressure is subject to the Chinese national standard with 47 paper standards ( CNS &gt; Α4 specification (210X297 mm) (Please read the note on the back before filling this page) Order B7 V. Description of the invention () The temperature increases and rises with the increase of peroxide concentration. In most experiments, the sterilization chamber is evacuated to 0.2 Torr, and the temperature is maintained at or above room temperature. (3) Hydrogen peroxide vapor can be generated from a hydrogen peroxide solution or an almost Anhydrous perylene complex is produced. The latter produces dry hydrogen peroxide vapor, which may be an advantage for the substance that will react with the vapor or the hygroscopic compound formed. Another advantage of the hydrogen peroxide compound to generate peroxide vapor is that the compound can generate a higher percentage of hydrogen peroxide vapor than aqueous hydrogen peroxide solution. This may be due to the use of hydrogen peroxide water When the liquid can generate vapor, water molecules and hydrogen peroxide vapor molecules compete with each other for the binding position on the complex. Argon peroxide vapor can also be placed in a sterilization room containing an object to be sterilized or another vacuum valve and sterilization room It is generated in the separated inner chamber. (4) The reaction time of the reaction substance and the over-gasification reaction depends on the reaction rate between the reaction substance and hydrogen peroxide. Printed by the Shellfish Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs can be monitored. The pressure is known from the experiment. The reaction pressure will decrease with the combination of the reaction substance and argon peroxide. The reaction time is about 5-30 minutes. The concentration of volatile hydrogen peroxide and the weight of the starting material determine the end of the reaction. The weight percentage of peroxide in the product. When the ratio of reactants to hydrogen peroxide increases, the weight percentage of hydrogen peroxide in the composite will decrease. The reaction can be repeated to increase the concentration of hydrogen peroxide in the composite. (5) Re-sterilize the chamber again; j: After the reaction of Citrus Straight is terminated, evacuate the sterilization chamber again to a pressure of about 2 Torr divided by ____48______. For paperless scales, use China National Standard (CNS) A4 (210X297). (%) A7 B7 printed by the Shellfish Consumer Cooperative of the Central Government of the Ministry of Economic Affairs. 5. Description of the invention () Remove any unreacted hydrogen peroxide. (6) The bacteria chamber is evacuated and the peroxide peroxide is removed. The mechanism of how hydrogen peroxide forms a complex with the reactants is still not completely clear. In general, the formation of the 彳 s complex involves hydrogen peroxide and argon bonding between the oxygen- and nitrogen-containing functional groups in the reactant. It is not clear whether this is the only bonding mode; however, it is also known that substances with diverse functional groups can also form complexes with europium peroxide. The gas phase reaction has the following advantages over other previously proposed methods for the production of argon peroxide composites: 1. The hydrogen peroxide can be accurately controlled by changing the hydrogen peroxide content in the vapor phase or the content of the reactants exposed to the vapor. Ratio of reactants. 2. It is no longer necessary to remove the solvent from the reaction product. 3. It can form peroxide compound liquid or solid, such as powder, crystal, film, and others. 4 · It is possible to prepare peroxide compounds of easily wettable substances. The following examples further describe the synthesis method of the non-aqueous peroxide compound of the present invention. Those skilled in the art should readily understand that many of these compounds can be used as catalysts in addition to the applications described herein. The examples represent examples of the composition and preparation method of the present invention, but the scope of the present invention is not limited thereby. Example 12 The preparation method of the complex formed by anhydrous glycine and thorium peroxide is as follows: ^ anhydrous glycine (Aliqi Chemical Company (Aldrich _______ 49 (please read the note f on the back before filling in this ear)) Order-5/3 -&quot; ·--V 'f 9 male 7 9 2 ehemical co.), Milwaukee, WI) was placed on an aluminum pan in a sterilization room with a temperature of 45 ° C and 173L. The top of the aluminum pan is covered with tyvekTM non-woven fiber to prevent the anhydrous dialysis acid from being selected from the pan when the sterilization chamber is decompressed but still breathing, and does not absorb hydrogen peroxide. Close the door of the sterilization chamber and reduce the pressure in the sterilization chamber to 0.2 Torr by pumping the air through the pump. An appropriate 70% hydrogen peroxide solution was allowed to evaporate into the sterilization chamber so that the argon peroxide roll reached 10 mg / L (FMC Corp., Philadelphia, PA). Keep the hydrogen peroxide vapor in contact with anhydrous glycine for 20 minutes. At the end of the reaction ', the pressure of the sterilization chamber was first reduced to 0.2 Torr, and then returned to atmospheric pressure. The product was removed and titrated with the following iodine to determine the weight percent of hydrogen peroxide in the product.

H202 + 2KI + H2S04 ^ I2 + K2S04 + 2H20 I2 + 2Na2S203 Na2S406 + 2NaI In the iodine-sodium thiosulfate titration reaction, starch is used as an indicator to improve the color change at the end of the reaction. Calculate the weight percentage of hydrogen peroxide with the following equation: wt% H2〇2 = [(Volume of Na2S203, ml) * (Concentration of Na2S203) * 1 · 7] / (gram weight, g) Central Standard of the Ministry of Economic Affairs The weight percentage of argon peroxide in the complex formed by anhydrous glycine and hydrogen peroxide was 2 4.3%. Example Many organic or inorganic compounds of argon peroxide can be prepared by the method described in Example 12. In each preparation, the reaction conditions are the same as those in the paper of Example 12 and the Chinese national standard (CNS) A4 specification (210X297 mm) is applied. Printed by the Shellfish Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs. A7 __B7 V. Description of the invention () Same , Except for the replacement of anhydrous glycine with 1 g of the compounds listed in Table 14.袅 14 Evaluation of compounds and weight percent of over-gasified hydrogen in compounds prepared by gas phase synthesis Chemical name 皋 Structure percentage after oxide treatment Poly (vinyl alcohol) [-CH2CH (OH)- ] n 18.9% ethanol poly (ethylene formazan) [-CH2CH (OCH3)-] n 22.0% ether poly (ethylene methyl ketone) [-CH2-CH (COCH3)-] n 13.9% acetone poly (acrylic acid) [- CH2CH (COOH)-] n 5.1% acid glycine H2C (NH2) (COOH) 20.7% amino acid L-histidine acid [N = CHNHCH = C] CH2CH (NH2) COOH 14.1% amino acid poly (ethylene ethyl ester) [-CH2CH (OCOCH3)-] n 9.1% ester cellulose acetate 10.9% ester sodium alginate 27.7% organic cellulose cellulose sodium sulfate 18.2% organic salt poly (4-acetamidine) [-CH2CH〇 &gt; -C5H4N)-] n 21.8% aromatic amine Histamine [N = CHNHCH = C] CH2CH2 (NH2) 13.2% Alanine (C2H5) CONH2 31.8% Amine urea (H2N2) CO 17.9% Urea 1,3- Dimethylurea (H3C) HNCONH (CH3) 31.7% Urea Bihalide (H3C) CO (NH) CO (NH2) 13.7% Dipyridine Polypropylamidamine [-CH2CH (CONH2)-] n 30.1% Polyfluorene Amine Polypyrrolidinone [-CH2CH (-N (CH2 ) 3CO)-] n 29.9% Polyamide nylon 6 [-NH (CH2) 5CO-] n 17.1% Polyamide nylon 6,6 film [-NH (CH2) 6NHCO (CH2) 4CO-] n 16.6% Poly The amine 51 paper size is applicable to the Chinese National Standard (CNS) A4 specification (2 丨 OX297 mm) (please read the note on the back before filling this page), βτ A7 _B7 V. Description of the invention () 袅 14 (Continued Jing) The chemical name of the chemically treated compound after the oxide treatment. The weight percentage of the chewing polyether polyaminocarbamate [-RHNCOOR '-] n 9.5% Polyurethane methyl ester sodium carbonate is called (: 03 14.3%). Inorganic potassium carbonate K2C03 33.9% Inorganic rhenium carbonate Rb2C03 37.0% Inorganic calcium hydroxide Ca (OH) 2 23.4% Inorganic sodium bicarbonate NaHCOj 10.7% Inorganic pyrolinic acid tetra sodium salt Na4P207 18.9% Inorganic (please read the precautions on the back first) (Fill in this page) The organic complex formed includes the following functional groups capable of forming hydrogen bonds with hydrogen peroxide: alcohols, ethers, ketones, acids, amino acids, esters, organic salts, amines, amidines, polyamines, polyamines Urethane, urea, and biuret. Inorganic complexes include carbonates with sodium, potassium, and sulfonium cations, and sodium bicarbonate. In addition, a complex formed by argon oxidation and tetra sodium pyrophosphate and hydrogen peroxide was also prepared. Except for nylon 6,6 and polyethylene nails, the starting materials are extremely fine powder or slightly larger crystals. Nylon 6,6 is a thin film with a thickness of 0.12 mm, while polyethylene methyl ether is 50. % Aqueous solution. Most of the hydrogen peroxide complexes made with these materials under test are solid, except for polyvinylpyrrolidone, histamine, poly (ethyl methyl ether), poly (ethylene methyl ketone), and acrylamide. , And 1,3-dimethyl urea. The complex formed by 1,3-dimethyl urea, propylamine and hydrogen peroxide is a free-flowing liquid, and it is extremely easy to handle in the vapor phase synthesis method, because there are fewer 52 paper sizes when obtaining the final product Applicable to China National Standard (CNS) A4 specification (210X297 mm) Ordered by the Central Bureau of the Ministry of Economic Affairs, printed by the Shellfish Consumer Cooperative, printed by the Central Standards Bureau of the Ministry of Economic Affairs, printed by the Consumers ’Cooperative, A7 ______________B7_ 5. Description of the invention () The solvent must be removed A step of. Histamine, polyvinylpyrrolidone, poly (ethyl acetomethyl ether) 'and poly (ethylene methyl ketone) are viscous products of resins and are not easy to handle. Examples 14 and 15 describe the use of polyvinylpyrrolidone to produce a free-flowing peroxide composite solid under different preparation conditions. 簏 Example 14 Composite of polyethylene p-pyrrolidone and hydrogen peroxide The preparation of the compound is to change the percentage of hydrogen peroxide in the polyethylene-pyrrolidone complex by changing the ratio of polypyrrolidinone to argon peroxide concentration in the vapor phase. The conditions for these tests were the same as in Example 12, except that the weight of polyvinylpyrrolidone was increased from ig to 3g and 5g. In all tests, the hydrogen peroxide concentration was maintained at 10 mg per liter of sterilization chamber volume. The test results are listed in Table 15. 15Example 15 Preparation of a complex formed by polyvinylpyrrolidone and hydrogen peroxide, in which the hydrogen peroxide used is released from a complex formed by hydrogen peroxide and urea. The hydrogen peroxide released in this way contains almost no moisture. In this test, 5 g of polyvinylpyrrolidone was placed in a reaction chamber and heated by 7 g of about 35 ° /. The argon peroxide-urea complex was brought to 11000c for 5 minutes to transfer argon peroxide at a concentration of 10 mg / l sterilization chamber volume to the reaction chamber. Other test conditions are the same as in Example 12. The percentage of hydrogen peroxide in the polyethylene terephthalmine compound and the physical state of the compound are listed in Table 5-5. (Please read the note f on the back before filling out this page)

• m V. Description of the invention (A7 B7 Table 1 5 Example 14 Gai Biyao also has a box ratio ratio of perforated gas in the clamp p and the peroxidation gas in the shadow honey complex of the physical state of the product Weight J ~ Fraction (%) 29.9 23.5 Example 1 5 Polyethylene "» Weight of ketalone (g) 1 3 5 5 19. Physical state of the product Soft sticky substance Hard sticky substance Free flowing solid Free-flowing solid skull test results show that by controlling the ratio of polyethylenpeltonone to peroxide gas in the vapor phase, or by using an almost anhydrous source of hafnium peroxide vapor, a free-flowing polyethylene can be produced. The compound is solid. (Please read the note on the back before filling in this page.) Order the hydrogen peroxide inorganic compound printed by the Ministry of Economic Affairs, the Central Bureau of Standards, Bureau of Industrial and Commercial Cooperatives, as described above. Can be used as a germicidal agent for peroxides. These inorganic compound compounds can be vaporized at room temperature and atmospheric pressure. However, as described below, a considerable amount of gas can also be released at atmospheric pressure and by reducing the inorganic compound to a specific release temperature. For effective compounding by inorganic The heating rate of the inorganic compound that releases argon peroxide vapor in the substance is preferably maintained at 5 ° C / min, less than 10 ° C per minute or 50 ° C / mi η, and most preferably at least per 0 C. Hydrogen Organic compound releases fast heating under argon peroxide vaporization under peroxide, peroxide: preferably up to 1000-line 54 paper size applicable to Chinese national standards (CNS &gt; A4 size (210X297 mm) V. Description of the invention () Table 16 lists some of these inorganic composites, and 2 weight ratio of hydrogen peroxide. The more suitable inorganic composites are those that do not decompose to produce acids. Therefore, particularly suitable composites It must not contain atoms. Peroxide mixtures can also be used as a source of peroxide vapor. Such mixtures can be physical mixtures, that is, two different peroxide compound preforms' or "chemical mixtures" ", That is, the compounds in the compound are mixed before the peroxide compound is prepared. The titration procedure used to determine the weight percent of hydrogen peroxide in the complex σ is as described in Example 12. The sodium carbonate hydrogen peroxide compound Forkat Company CF 1 uka C hem 1 ca 1 c rp., R 0 nk nk nk oma, N γ). The vapor phase method used to synthesize the peroxide inorganic composite was as described in Example 12, except that 10 g of solid The inorganic sample was used to replace the solid inorganic sample of 1-5 Lu, and two cycles were performed instead of one. Example 16 The reaction steps for the liquid phase synthesis of hydrogen peroxide inorganic compounds are as described by John and his colleagues (J. C hem Soc., Da 11.n, 12: 2 5 2 6-2 5 32, 198 0). In short, the inorganic solid is first dissolved in a 300/0 argon peroxide aqueous solution to form a saturated solution, and then acetic acid is added dropwise. As for the complex of potassium oxalate and thallium carbonate, when the added ethanol gradually increases, That is to say, a white precipitate of carbonic acid, potassium potassium pyrophosphate and sodium pyrophosphate can be formed. The saturated solution can be placed at ° C for several hours to promote the formation of peroxide complex crystals. The composite was separated from the liquid by vacuum filtration, and washed with ethanol at least three times and dried under vacuum. (Please read the notes on the back before filling in this book) ir Printed by the Central Consumers Bureau of the Ministry of Economic Affairs, Consumer Cooperatives

Printed by A7 _____B7, Zhengong Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs. 5. Description of the invention () 重量 16 Weight percent of hydrogen peroxide in the compound and the chemical name of the compound being evaluated. Purchase 2 Vapor 3 Liquid 3 Sodium Carbonate Na2OO3 27.35 Potassium Carbonate K2C03 7.43 22.70 Rhenium Carbonate Rb2C03 20.31 26.78 Potassium Oxalate K2C204 16.13 16.42 Sodium Pyrophosphate Na4P2〇7 11.48 23.49 Potassium Pyrophosphate K4P2O7 20.90 32.76 Sodium Orthophosphate Na3p〇4 15.67 Potassium orthophosphate K3PO4 16.11 1. The titration procedure used to determine the weight percent of hydrogen peroxide in the complex is as described in the previous patent application. 2. The sodium carbonate hydrogen peroxide complex was purchased from Fluka Chemica Corp, Ronkonkoma, NY. 3. The vapor and liquid phase methods were used to synthesize the inorganic compound. An energy difference scanner ( DSC) (Model PDSC 2920, TA and Metler-Toledo Model DSC 2 7HP instruments) to determine the decomposition characteristics of the released hydrogen peroxide or this inorganic peroxide complex. Under atmospheric pressure and various vacuum pressures, the DSC heating rate is set to 10 ° C / min, and the temperature range is between 30 ° C and 220 t. Referring to Figure 5, the DSC includes a sample chamber 110, a heating plate 112, and a pressure control system. The pressure control system includes a pressure transmitter 114 connected to a pressure gauge 116. The pressure gauge 116 is connected to a controller 118 and then to the pressure control valve 120. Pressure transmission sub U4 and pressure control valve 120 and true __56__ This paper size is in accordance with China National Standard (CNS) A4 (210X297 mm) ---------- # '----- --1T ------ (Please read the note on the back before filling in this page) Printed by the Central Bureau of Standards of the Ministry of Economic Affairs® C Industrial Consumer Cooperative A7 _______B7_____ V. Description of the invention () Air pump 1 2 2 The communication is through liquid rituals. The potassium oxalate hydroperoxide complex synthesized in the above manner was placed in DSC 'and a specific vacuum pressure was applied in a temperature range of 50 ° C to 170 t. As shown in Figure 6, 'Under such d SC conditions and the sample pan cover has only a small hole,' the endothermic reaction is more favorable at low pressure and a larger amount of hydrogen peroxide can be released ', and it is more favorable at high pressure. The exothermic reaction of decomposition of hydrogen peroxide proceeds. However, as shown in Fig. 10, if this experiment is repeated at atmospheric pressure without covering the plate, only a part of the peroxide will be released. Therefore, for some nitrogen peroxide compounds, a more open system and / or reduced pressure can promote the release of hydrogen peroxide from the compound. When using the inorganic compound of peroxide to sterilize, the stability of the compound is a very critical factor when heating rapidly. 'Fast heating can be achieved by preheating the aluminum pan before contacting the inorganic composition of the peroxide. When using a peroxide-containing inorganic composite, the temperature is preferably higher than 8 6 ° c. As described above, it is preferable that the inorganic compound capable of rapidly heating the peroxide, that is, 1 000 ° C / min or faster. This can be achieved by contacting the inorganic composition of the peroxide with a pre-heated aluminum pan. Figures 7A and 7B show a preferred embodiment capable of achieving such a rapid heating process. The figure shows a device 125 capable of injecting peroxide vapor into a closed sterilization chamber 131. The hydrogen peroxide inorganic compound is contained in a peroxide disc 132. This plate 132 has five layers: three layers of CSR coating, peroxide compound powder, and aluminum foil coated with polypropylene. The disc 132 is heated with its edges sealed to retain the peroxide compound vapor. The peroxide plate 1 3 2 is placed under a hole-shaped name plate 3 0. The hole-shaped aluminum plate 1 3 0 is connected to the seat 1 5 0 by an aluminum connection block 1 4 2. Peroxide ___57_____ This paper is different from A, SS, and Household (CNS) A4 (210X297 gong) &quot; &quot; (Please read the precautions on the back before filling out this page) Order by the Central Standards Bureau of the Ministry of Economic Affairs Printing A7 _B7_ V. Description of the invention () The compound plate 1 3 2 is loosely fixed with a 0-shaped ring 1 5 1. Before peroxide vapor is introduced into the sterilization chamber, a heated aluminum platen 134 away from the peroxide plate 132 is connected to the aluminum plate 136. A spring (not shown) in the box 138 holds the disc 136 down in the closed position. When the chamber 131 is evacuated, the box 138 also becomes a vacuum. The disk 136 is located opposite the 0-ring 148, so that the peroxide release chamber 152 can be separated from the channel 158. The device is connected to the sterilization chamber 131 by means of the plugs 144, 146, 154, and 156 and fixed. Referring to FIG. 7B, in order to allow the aluminum platen 134 to contact the peroxide disc 132 upwards, "let the box 138 vent"-once the pressure increases, it will move the box 138 upwards. Therefore, the heated aluminum platen is pushed 134 upwards is opposite the peroxide disk 1 3 2. In a preferred embodiment, the aluminum platen 1 3 4 is preheated to 17 5 ° C; however, other temperatures are also possible. The peroxide vapor passes through the CSR layer and is released from the powder, passes through the hole 160 in the porous aluminum plate 130, and enters the peroxide release chamber 152. The upward movement of the aluminum pressure plate 134 will also open the peroxide release chamber 152, so that the peroxide vapor can enter the passage 158 connected to the sterilization chamber by the liquid. Referring to Fig. 8A, the figure shows that the sterilization chamber 17o contains many glasses at right angles to each other. #Stem 172 ° Stainless steel blades 174 and 176 containing vibrio_bacteria jiearoi / ierwo- are placed at the bottom and above the bacterial chamber 170, respectively. Shown to the right of the sterilization chamber 170 is a device 178 for heating a hydrogen peroxide complex, such as a hydrogen peroxide complex of sodium pyrophosphate (Na4P207. 3H2O2) and potassium oxalate (K2C204.h202). The device 178 includes a pyrex bowl located at the bottom of the sterilization room 170. The paper coffee is made in China ^ cNS) A4 ^ training coffee (by reading the note on the back before filling this page)

Printed by the Shellfish Consumer Cooperative of the Central Bureau of Standards and Quarantine of the Ministry of Economic Affairs Α7 Β7 V. Description of Invention () 180. Above Perry's Bowl 180 is a Perry's Plate 182. On the Parrish disk 182 is an aluminum disk 184 containing a heating pad 186. The peroxide compound is contained in the aluminum disk 184. An electric wire 188 is connected to the heating pad 186 and a thermal paddle 190 is connected to the signboard 184. The blade 174 is placed two inches above the aluminum plate U4. In some embodiments, the hydrogen peroxide compound is provided in the form of a separate enclosure, and the enclosure is in communication with the container containing the object to be sterilized by the liquid. The pressure in the enclosure and the container may be the same or different. Positive differential pressure in the enclosure promotes the release of peroxide vapor from the peroxide compound in the enclosure into the sterilization container. This positive differential pressure is particularly useful for large containers, such as the entire room. In another preferred embodiment, a powdered peroxide compound is applied to a sticky surface. More suitable adhesive surfaces include high temperature adhesive tapes such as A10 and A125 adhesive tapes (3M Corp., Minneapolis, MN). The devices 3A, 7A and 8 were used to heat the adhesive tape coated with the powder type peroxide compound to promote the release of peroxide. Referring to Fig. 9, a high-temperature adhesive tape 200 containing a peroxide compound powder 202 is placed on the aluminum foil layer 204. The adhesive tape layer 200 is then added with one or more CSR layers 206. This can be done as a single sheet of material or as a roll of all materials. The inorganic peroxide complexes used in Examples 17 and 18 to determine the amount of peroxide released and the bactericidal effect are potassium pyrophosphate (K4P2O7. 3H2 ° 2: pp), oxalate (K2C2O4. H2〇2; P〇 ) And sodium carbonate (Na2C03.1.5.202: SC). _59_ This paper is again applicable to the Chinese National Standard (CNS) A4 specification (2 丨 0 χ 297 mm) (Please read the note f on the back before filling out this page),?! Grade invention description (Central Bureau of Standards, Ministry of Economic Affairs) The example of the printing of the Cooper Consumer Cooperative is the ideal temperature of the release of hydrogen peroxide from SC, P0 and pp. The ideal temperature of the release of hydrogen peroxide from SC, P0 and pp is determined by DSC. The 75L sterilization chamber and the 7th ~ Bth solid The device at various temperatures measures the actual amount of hydrogen peroxide released from 2g of this type of compound. The peroxide gas released from pp is higher ^ the amount released from sc * p0. Although At l75t, the amount of peroxide gas released from Sc is the smallest, but when the product quantity is added, the amount of nitrogen peroxide released can be significantly increased.

75L sterilization chamber contained SC released peroxide SL released hydrogen peroxide amount EQ E £ (based on DSC) 170 ° C 150 ° c 130 ° C 2g sample at 125 ° C 0.3mg / L 0.8 mg / L 1.0 mg / L 1.2 mg / L 2.0 mg / L 1.5 mg / L at 150 ° C 1.8 mg / L 2.5 mg / L 3.4 mg / L 3 mg sample at 175 ° C 2.3mg / L 4g sample at 175 ° C 2.9mg / L at 175 ° C This paper size is applicable to China National Standard (CNS) A4 specification (210X297mm) Please fill in this page again) A7 B7 V. Description of the invention () Example 1 «The efficiency test with SC, P0 and PP will be 2 χ 106

Mked) inoculated on stainless steel blades. The three inoculated blades were placed in front of, in the middle of, and at the rear end of a 10-inch x 21-inch x 3 5-inch polystyrene oxygen disk covered with SPUNGARD. After that, the coated plate was placed in a 75L vacuum sterilization chamber with an initial pressure of 0.2 Torr, β, and the inorganic peroxide powder of sc, SO or pP was sealed on three layers of SPUNGARD and a layer of aluminum foil with polypropylene film. To form a 5.5-inch peroxide disc. By contacting this disk with an aluminum plate that has been preheated to 175 t for 2 minutes to release the peroxide, and then allowing it to diffuse for 8 minutes to achieve a total exposure time of 10 minutes, "the three blades were treated separately. It was placed in trypsin soy medium and cultured at 32 ° C for 7 days to observe the growth of bacteria. The results are summarized in Table 18. Table 18 Efficiency test results (please read the note on the back before filling this page)

&gt; 1T Printed Peroxide Complex Complex Bactericidal Complex (Positive Concentration / Concentration of Samples, PP 2g 3.4 mg / L 0/3 ΡΟ 2g 2.5 mg / L 0/3 SC 2g 1. 8 mg / L 1/3 SC 3g 2.3 mg / L 0/3 SC 4g 2 · 9 mg / L 0/3 __61 This paper is made of t-membrane S household samples (CNS) Eighty-fourth secret (210X297 mm) printed by the Central Standards Bureau of the Ministry of Economic Affairs, Shellfish Consumer Cooperative, printed A7 _ B7 V. Description of the invention () As shown in Table 18, except for the 2gSC (l / 3) group, the other groups were not observed There are signs of bacterial growth. However, when the amount of SC used is increased to 3g, there is no bacterial growth. These results show the bactericidal effect of the inorganic compound with peroxide gas. The inorganic compound of hydrogen peroxide can be Easily incorporated into the sterilization steps described above with organic hydrogen peroxide compounds for sterilization. For example, inorganic compounds can be used with plasma sterilization, or with enclosures that can self-sterilize—with the use of peroxides. Can be slowly released from the compound in the enclosure. Similarly, no The organic compound can also be used for sterilization of Zhao with a narrow inner chamber, where the inner chamber is in communication with a container containing the inorganic peroxide compound. In addition, pressure pulses can also be used to make steam from the inorganic peroxide compound After referring to the specific examples of the present invention, other examples of sterilization with inorganic peroxide compounds will be apparent to those skilled in the art. Phosphate and concentrated phosphate overgas compound Synthesis of certain compounds Table 19 summarizes certain phosphate and concentrated phosphate peroxide complexes with the synthetic methods mentioned in this article. Generally speaking, the synthesis of these complexes can be achieved by mixing phosphate with an aqueous hydrogen peroxide solution. (Add the solid to the aqueous solution of peroxide or add the aqueous solution of peroxide to the solid). Because the heat generated by the reaction may cause the decomposition of hydrogen peroxide, try to slowly mix the solid with the aqueous solution of peroxide or A low temperature (ie, 0 ° C) aqueous peroxide solution is used to control the reaction temperature. It can also be dissolved in phosphate hydrate or in peroxide water. Concentrated phosphate in the liquid to form a peroxide complex. ----- 62 This paper size applies the Chinese National Standard (CNS &gt; M Specification (2ΐ〇χ297mm) --------- C ------ 1T ------ ^ (Please read the notes on the back before filling out this page) 5. Description of the invention ()

AB Printed by the Central Bureau of Standards, Ministry of Economic Affairs, Shellfish Consumer Cooperatives. 19 Starter Synthesis Chemical Formula References Solid hydrogen peroxide 265% Slowly add Na2P207 to the aqueous hydrogen peroxide solution to control the temperature below 50 ° C Na2P2. 7 · ΝΗ2〇2 n = 2, 3 or higher 1 Na ^ P 2 07 250% react 3 Molar 50% H2O2 with 1 Molar Na4P2 07, dry Na4P2 0 on a flow bed at low temperature 3H2〇2 2 Na4P207 .ioh2o2 30-90% Na4P2〇7 · 10H2〇2 was added to the H2O2 solution and dried under vacuum at 20 ° C Na4P2 07 3H2 2 3 Na3P04 12H2 2 2 30% Add Na3P04.12H2O2 to the H2O2 solution and vacuum dry NajPO ^ at 20 ° C ^ 5H2O2 4 Na2HP04 • 12H202 4-76% Add Na2HP04.12H2O2 to the H2O2 solution Na2HP04 NH2〇2 n = 1, 2 4 Na5P3 0, 60% in a vacuum bed at 20 ° C. Spray the solution of Na2P04 on NajP ^ OlO at 40-50 ° C on a flow bed, and then Dry Na5p3 ° 10 _ NH2〇2 n &lt; l 5 K3P〇4 · 7H2〇2 65-70% 〇3c in a h2O2 solution to dissolve KK3PO04.7Η2 02, and keep the temperature below 70 ° C K3PO4 NH2〇2 n = 1, 2,4 6 K4P2 07 60-90% K4P2 07 was added to the H2O2 solution to maintain the temperature below 50 ° C. The results show that when a large amount of starting material (i.e. ' 174g), this method cannot form any composites. K4P2O7 * NH2O2 n = 5.35,7 7 1. Richmond, Howard, PCT Publication No. WO 95/05431 63 This paper is applicable to the Chinese National Standard (CNS) A4 specification ( 210X297 mm) ----- IT ------ 0 (Please read the note f on the back before filling this page) Printed by A7 B7, Shellfish Consumer Cooperative, Central Procurement Bureau, Ministry of Economic Affairs ) 2. Xiao et al., Faming Zhuanli Shenging Gongkai Shoumingshu, CN 1,097,798, 25 Jan 1995. 3. Titova et al. Russ. J. Inorg. Chem. 40 (3): 384 (1995) 4. Titova et al · Russ. J. Inorg. Chem. 39 (5): 7544 (1994) 5. Kudo, I., Japan Kokai, (C1.C01B), Aug. 29, 1975, Appl. 74 15,389, Feb. 08, 1974. 6. Kirsanova, MP, Bogdanov, GA, Dymova, ZN, Safonov, VV, Izv. Vyssh. Ucheb. Zaved. Kjim. Khim. Tekhnol. 15 (2): 183-6 (19752). 7. Majewski, HW, US Patent No. 3,650,750. Spraying method is similar in the literature The method described is determined to present a process for preparing phosphates and phosphate was concentrated and restrict the degree of difficulty. Generally, the composite is prepared by uniformly spraying a peroxide solution on a salt solid and drying it under vacuum. Table 2 summarizes the complexes synthesized by this spray method ^ Na 4 P 2 0 7 · 3H2O2 cannot be prepared at 30% H2O2, which is the same as described in the previous literature. The K3P04 peroxide complex cannot be prepared by directly adding a hydrogen peroxide solution to an anhydrous K 3 P 0 4 solid at room temperature. For detailed synthesis conditions, see Examples 21 to 36 below. 64 This paper size applies to China National Standards of Standards (CNS) Α4 (210X297 mm) ^ 1ί1τ '^-(Please read the precautions on the back before filling out this page) A7 B7 Shellfish Consumer Cooperative, Central Bureau of Standards, Ministry of Economic Affairs Printed paper Description of the invention (A.20 Example of the chemical formula of the starting material solid 氲 Peroxide Na &lt; 卩 2 07 &gt; 50% Spray an argon peroxide aqueous solution on the Na4P207 solid n »4p2 ° 7. Nh2 ° 2 n = 3, or higher 丨 ---- Ί. 21-27 Na4P2〇7 3 0% neck hydrogen peroxide solution is sprayed on Na4P2〇7 solid N ^ 4P2〇7 · ΝΗ2Ο2 π &lt; -2 26 Na3P 〇4 3 0-70% Aqueous hydrogen peroxide solution was sprayed on Na3P〇4 solid Na3P04 · 5Η2〇2 28 Na2HP04 3 0-7 0% Aqueous argon peroxide solution was sprayed on Na2HP04 solid Na2HP〇4 · Ν 2Ο2 η = 1,2 29 Na5P3O10 3 0-7 0% Spray an aqueous solution of argon peroxide on Na5P30 丨 Solid Na5p3 ° 10 * ΝΗ2Ο2 η ~ 1 &gt; 2 3 0 k3P04 5 9% non-argon peroxide solution is sprayed on No complex on k3P04 solids 3 1 k4p2〇7 5 9-70% Sprayed with argon peroxide solution on K4P207 solids 4Ρ2 ° 7 * ΝΗ２〇2 η = 4-7 32 K2HP〇4 5 9% Aqueous argon peroxide solution was sprayed on the K2ΚΡ〇4 solid K2ΗΡ〇4 3 · 15Η202 3 3 KH2P〇4 5 9% Hydrogen peroxide Aqueous solution is sprayed on K2P04 solid KK2P0 4 1 2202 2 4 Ca2 2 07 5 9% Aqueous argon peroxide is sprayed on Ca2P2 07 solid Ca2P2 ° 7 3.42 2 0 2 3 5 Mg2p2 ° 7 5 9% 4 Aqueous argon peroxide solution is sprayed on Mg2P2 07 solid Mg2p2 07 4.60 2 0 2 36 Synthesis of Na4P 2 by the spray method of dredging. In general, sodium pyrophosphate and hydrogen peroxide The formed anhydrous compound is synthesized by liquid spraying method plus vacuum and or drying. 65 JL common Chinese national standard (CNS) A4 size (210X297 mm) is sprayed with liquid radon (please read the back first) Note ($), then fill in the original) A7 printed by the Shellfish Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs ______ —__ Β7_ V. Description of the invention () ~ '' Method to prepare the compound of pyrophosphate and argon peroxide Change many parameters, see the following examples 21-27. Spray concentrated hydrogen peroxide solution (30—90%) dropwise on coke. Cassock acid (98%, Adelaide Aldrich Chemical Co.). Let the mixture 10 ° C, 25 ° C, or 45 ° C. (: Incubate for 1-6 hours, then vacuum dry at 25t-6 (TC or dry in an oven at 60 ° C. In the following example 'change the hydrogen peroxide concentration, the molar ratio of hydrogen peroxide to Na4P207 at the beginning , Solid-liquid ratio, incubation time and temperature, drying form 'drying temperature and amount of starting material to determine their effect on product composition β Example 2 1 to 2 3 show the reaction method at 2 5 ° C after 2 hours, drying method (respectively Is the effect of vacuum drying at 30 ° C, vacuum drying at 60 ° C, and drying in an oven at 60 ° C) on the final weight percentage of argon peroxide of the resulting composite. Example 2 4 shows a vacuum at 25 ° C Effect of reaction time during drying 干燥 The results show that a reaction time of 1 hour is sufficient to form a complex with a ratio of sodium pyrophosphate to nitrogen peroxide of 1: 3. Example 25 shows the effect of reaction temperature on the formation of a peroxide complex. The results show that when a small amount of starting material is used, a complex of sodium pyrophosphate and peroxide gas with a ratio of 1: 3 can still be formed at a temperature below 45t. Example 26 shows that the concentration of argon peroxide versus the liquid spray method Peroxide complex The effect of the composition of the compound. As shown in Table 21, when 30% H2O2 was sprayed on the sodium pyrophosphate solid, even though the H2O2 to SP ratio was 1: 4 at the beginning, the resulting complex Na4P2 07. The ratio of H2O2 to SP of 1.64H2O2 is still lower than 2: 1 (bis-peroxyhydrate). When the concentration of H2O2 is higher than 45%, preferably higher than 50%, it is feasible to become three. _______66______ One I paper size: China National Standard (CNS) A4 size (210X297 mm) ~ &quot; I installed-', ----- ordered ------ line! Γ,' ( Please read the notes on the back before filling this page) A7 B7 V. Description of the invention () Tris-peroxyhydrate (Na 4 P 2 〇7. 3H2 〇 2). The ratio of h2〇2 to SP is 4 : 1's Na4P2 07. 4H2 2 ''s composition is stable only at temperatures below 60 ° C. Example 27 shows that when a large amount of Na4P2 07 is used, it is not possible to prepare sodium pyrophosphate tris by liquid spraying. Peroxohydrate complex β Example 21 Vacuum drying H2O2 (59%) at 30 ° C with sodium pyrophosphate in a weight-to-solid ratio of 1: 0.8, 1: 0.9 and 1: 1 After 2 hours at 25 ° C , Dry under vacuum at 30 eC for 4 hours or 30. (: Dry under vacuum for 4 hours and then dry at 60 ° C for 15 hours. The yield of the obtained product is in the range of 84% to 99%. Summary of results In Table 2 1 ® (Please read the note on the back before filling out this page)-Order printed by the Central Ministry of Economic Affairs, Central Bureau of Standards, and Shellfish Consumer Cooperatives. Table 2 1 The weight of the starting compound at 25 ° C Percent reaction time SP 59% ¾ H2〇2 / S 30 ° C vacuum drying at 30 ° C 4 〇2 Pmor vacuum drying hours plus 60 ° C dry number ratio drying 15 hours (g) (g ) (g) 4 hours closed 1 open 2 l0g 8g 3.7 2 hours 13.5 26.81 26.11 26.18 l0g Η 4.2 2 hours 13.9 27.75 26.95 26.98 l0g Hg 5.1 2 hours 11.7 27.75 26.61 26.88 67 Ruler paper is not allowed to be rubbed Tsukaki Akira r State Λ cm. 97 V. Description of the invention (A7 B7 1. In a closed condition, the 'composite is placed in a closed plastic bottle; 2. In an open state, the' composite is placed in a Open Petri Dish. Example 2 Vacuum drying at 2 60 ° C 2 0 2 (59%) and sodium pyrophosphate are mixed in a solid-liquid ratio of j: 〇8, 1: 〇9, and 1: 1.1 by weight ratio at 25r After 2 hours of reaction, it was dried under vacuum at 60 ° C for 4 hours. The results are summarized in Table 2-2. $ Chuanban Zhunbei J. Cooperative Co., Ltd. 22 Μ: Initial compound reaction time reaction temperature H2O2% by weight SP 59% H2O2 H2O2 / SP Molar number than 60 ° C vacuum drying 6 (TC at its Dry for 4 hours and add 60. (: Dry for 15 hours (g) (g) (hours) ICC) 4 hours 1 open 10 8 3.7 2 25 26.54 25.53 10 9 Bu 4.2 2 25 26.92 26.38 10 11 5.1 2 25 26.83 26.28 Jfe »j 2 3 6 0 ° C drying in an oven 〇 2 〇2 (59%) and sodium pyrophosphate in a solid-liquid ratio of j: 〇8, 1: 0. S and 1: 1 by weight ratio Mix and react at 25 ° C. After 2 hours, dry in an oven at 60 ° C for 6 or 21 hours. The results are summarized in Table 23. ___68 This paper uses the Chinese National Standard (CNS) ) A4 specification (210X297mm) --------- # 0 ----- 1T ------ line (please read the notes on the back before filling this page) A7 B7 V. Invention Description () Table 23 Reaction time of starting compound Weight percentage of reaction temperature H2O2 SP 59% H2O2 H2O2 / SP Molar ratio 60 ° C Dry in oven (g) (g) (hours) (° C ) 6 hours 21 hours 10 8 3.7 2 25 27.22 26.83 10 9 4.2 2 25 27.10 26.87 10 11 5.1 2 25 29.57 26.74 (Please read the notes on the back before filling out this page) Example 24 Effect of reaction time Η 2 〇2 (59%) Sodium phosphate was mixed at a solid-liquid ratio of 1: 0 · 8, and reacted at 25 ° C for 1, 2, 16 hours and vacuum-dried at 25 ° C for 4 hours. The results are summarized in Table 2. 4 in.

1T printed by the Consumer Cooperative of the Central Bureau of Standards and Quarantine of the Ministry of Economic Affairs24 Initial compound reaction time Reaction temperature H2O2% by weight SP 59% H2O2 H2O2 / SP Molar number 25 ° C under vacuum at 25 Dry under vacuum for 4 hours plus 60 ° C for 15 hours (g) (g) (hours) (° C) 4 hours open 10 8 3.7 1 25 27.45 26.77 10 8 4.2 2 25 26.81 26.18 10 8 5.1 16 25 27.01 26.96 25 * 20 3.7 16 25 27.12 26.90 69 This paper size is applicable to China National Standard (CNS) Α4 size (210 × 297 mm) Printed by Zhenong Consumer Cooperative, Central Bureau of Standards, Ministry of Economic Affairs A7 B7 V. Description of invention ()

篪 Example 2S The reaction temperature of Yingxin 2 〇2 (59%) and sodium pyrophosphate were mixed in a solid-liquid ratio of 1: 0.8, 1: 1, 1.1 and 1: 1.3, respectively. The reaction was performed at 10 ° C, 25 ° C or 45 ° C, and dried under vacuum. The results are summarized in Table 25.袅 25 7 Therefore, the initial compounding and h reaction time reaction temperature H2O2% by weight SP 59% H2O2 H2O2 / SP Molar number ratio vacuum drying at 25 ° C vacuum drying at 45 ° C (g) (g ) (Hours) (° C) 4 hours 2 hours 10 8 3.7 2 10 27.81 10 8 4.2 2 25 26.81 25 27 5.0 1.5 45 26.07 25 32.5 6.0 1.5 45 27.23 SUH 26 Η 2 〇2 The effect of concentration will be Η2 〇2 solution was added dropwise to sodium pyrophosphate (98%, Adrige Chemical Co., Ltd.) "The mixture was incubated at 25 ° C for 2 hours, then dried at 25 C under vacuum for 4 hours, and then in an oven at go ° c Dry for 15 hours except for the samples in the bottom row of Table 26. The samples in this column are dried under vacuum at 25 C for 4 hours, and then dried in an oven at 40 ° C for 9 hours .--------- -装 Π ----- ΐτ— · ----- 0 (Please read the note on the back ^ • before filling this page)

°? = @ Ηόχ ¥ η @ · &gt; ° ¥ ητ == ςατ〇ίαν L ?? ^? Ι · ηός @ ηύ =? Σ © ·? Σα ¥ η · 00ν ° © · τ〇ία η1-? Στ Β7 V. Description of invention (). The results are summarized in Table 26. The results show that a higher concentration of peroxide is required to prepare a peroxide compound having a ratio of Η2 02 to SP of about 1: 3.袅 26 Weight of starting compound complex H2O2 Concentration of H2O2 H202 / SP Molar ratio to H2O2 Weight percentage composition (g) (g) (%) 10 15.8 30 3.7 15.69 He 4 卩 2 〇7 · 1.46H2〇2 10 17.2 30 4.0 17.36 Na4? 2〇7 '1.64H2〇2 10 11 45 4.0 25.48 shirt 4 卩 2 07. 2 · 6Η 202 10 8 59 3.7 26.18 Na4P2 07 * 2.78H2 2 10 9 59 4.2 26.98 Na4? 2〇7 · 2.89H2〇2 10 12 90 5.6 27.16 You 4 卩 2〇7 · 2.92H2〇2 10 12 90 5.6 34.44 * Na4P2〇7. 4.11H2〇2 (Please read the back first (Please note this page and fill in this page again), Γ- &quot;. Ordered by the Central Ministry of Economic Affairs, Central Bureau of quasi-station, shellfish consumer cooperatives * Samples are vacuum dried at 25 ° C for 4 hours, and then dried in an oven at 40 ° C Dry for 9 hours. Example 27 Effect of starting material content Slowly spray a 59% H2O2 solution on sodium pyrophosphate solids at room temperature; however, the temperature of the mixture will rise. When 59% of H2O2 is dissolved, the paper size is in accordance with Chinese National Standard (CNS) A4 specification (210 × 297 mm) A7B7 V. Description of the invention () The solution is added to 300 g of sodium pyrophosphate (SP) solid At this time, the temperature of the mixture rose above 60 ° C. Therefore, using a large amount of SP is not as effective as using a small amount of SP. The results are summarized in Table 27. Table 27 Temperature during mixing of starting compounds CG) Incubation time at 25 ° C Drying conditions H2〇2 Weight percent SP 59% H2 02 H202 / SP Molar ratio (g) (g) (hours) 10 8 3.7 ~ 35 1 Vacuum drying at 25 ° C for 3.5 hours plus oven drying at 60 ° C for 15 hours 26.77 100 80 3.7 ~ 45 3 Vacuum drying at 25 ° C for 3.5 hours plus oven drying at 60 ° C for 15 hours 25.86 300 250 3.7 Vacuum drying above 60 3 45 ° C for 15 hours. 19.98 Printed by the Shell Cooperative Consumer Cooperative of the Central Samples Bureau of the Ministry of Economic Affairs (please read the precautions on the back before filling this page). Several other liquids of peroxide compounds are sprayed. Sprinkler synthesis is detailed in Examples 28 to 34 below. 72 This paper size applies Chinese National Standard (CNS) A4 specification (2 丨 0XW7 mm) 5. Description of the invention () SLM 28 uses liquid spray synthesis to synthesize Na3P〇4. 5H2〇2 will have a concentration of 30%, 59%, and 70% aqueous hydrogen peroxide solution was sprayed on a three base sodium orthophosphate solid (SPT; 96%, Adrige Chemical Company) to form a mud. The mixture was allowed to incubate at 25 ° C for 2 hours, and then dried under vacuum at the same temperature. The results are summarized in Table 28. ^ 2J8

Starting compound complex Na3P〇4 H2O2 weight H2O2 H2O2 ^ Na3P0 4 H2O2 Group concentration Concentration Molar Specific gravity% (g) (g) (%) --- ---- 5 34.6 30 10 51.70 Na3P〇7T- 5.16H2〇2 5 17.6 59 10 52.23 Na3P〇 ^ r- 5.27H2〇2 5 14.8 70 10 48.81 Na3P〇j7 4.6〇H2 02 2J Wei Zheng 29 sheets __The Ministry of Economic Affairs, Central Bureau of Quasi-Institute of the Ministry of Economic Affairs and the Consumers Cooperation Du Yin produced a liquid spray synthesis method to synthesize Na2HP〇4. (Adrige Chemical Co., Ltd.) was dissolved in an aqueous hydrogen peroxide solution and the mixture was allowed to incubate at 25 ° C for 1 hour, and then vacuum-dried at the same temperature to obtain a Na2HP04H2 02 ratio of 1: 2 of gelatin products. This gum was further dried to obtain a powder having a ratio of N a 2 Η P 0 4 / Η 2 02 of 1: 1. The results are summarized in Table 73. 1 Applicable to China National Standard (CNS) A4 specification (2 丨 0297mm B7 V. Description of the invention) 29. Table 29 Weight of the starting compound complex Na2HP04 H2 02 H2 02 The molar number of the concentration H2〇2 / Na 2HP〇4 is more than the weight percentage of H2O2. The weight percentage of H2O2 is composed of (g) (g) (%). It is in powder form 5 12.0 30 3.0 20.37 Na2HP 〇4 · 1.07H2〇2 5 19.8 30 5.0 33.72 Na2HP〇4 · 2.12H2〇2 23.01 Na2HP04 · 1.25H2〇2 5 6.1 59 3.0 27.88 Na2HP〇4 · 1.61H2〇2 22.28 Na2HP04 -1.20H2 02 2 10.2 59 5.0 35.33 Na2HP04 · 2.28H2〇2 20.85 Na2HP04 · 1.10H2〇2 5 5.1 70 3.0 31.31 Na2HP04 · H2〇2 5 8.5 70 5.0 35.13 Na2HP〇4 · 2.26H2〇2 21.49 Na2HP04 * 1.14H2 02 (Please read the back first Please fill in this page if you want to add $.) • 1 '·-, &lt; ·· _ -β Printed by the Consumers' Cooperative of the Central Bureau of Standards, Ministry of Economic Affairs, Example 30. Spraying synthesis method of liquid Zhao to synthesize Na5P30.1. 1 · 2Η2 0 2 Drop the concentrated aqueous solution of nitrogen peroxide dropwise on the solid sodium tripolyphosphate (85%, Adriatic Company) (SPT). The mixture was allowed to incubate at 25 ° C for 1 hour, then vacuum dried at the same temperature, and dried in an oven at 60 ° C. The results are summarized in Table 30. Paper size applies Chinese National Standard (CNS) A4 specification (210X297mm) 5. Description of the invention () 袅 30 Starting compound complex Na5p3 ° 10 H2O2 weight H2O2 concentration 22002 / N &amp; 5P3. Molar number of 10 than weight percentage composition of Η202 (g) (g) (%) 10 13.0 30 5.0 10.58 Na5p3 ° 10 * 1.4H2〇2 10 6.6 59 5.0 1 · 12.58 Na5p3 ° 10 '1.62H2〇2 10 5.6 70 5.0 13.40 Na5p3 ° 10 · 1.73H2〇2 (Please read the precautions on the back before filling this page) Example 31 Synthesis of K3P〇4 by liquid spray synthesis method. NH2〇2 at room temperature • 59 % H2O2 solution was added dropwise to a potassium base tribasic solid (97%, Adrige Chemical Co.). The temperature of the mixture continued to rise to 80 ° C during spraying. This slimy mixture was dried under vacuum for 4 hours. The results are summarized in Table 31. Order 31 The weight of the reaction of the starting compound KK3P04 H2〇2 The concentration of H2 02 H202 / K3P04 The mole ratio of H202 / K3P〇4 is the weight percentage of H2 02 (g) (g) (%) 10 8 59 3.0 '0.34 K3PO4 * 〇.〇2Η2〇2 This paper size is applicable to China National Standard (CNS) A4 (210X297 mm), printed by the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs V. Description of the invention () Example 32 Synthesis of K4P2O7 by liquid Zhao spray synthesis method. NH2〇2 At room temperature, a 59% or 70% solution of Η2 〇2 was sprayed on potassium pyrophosphate (PP). ) On solids (97%, Adrige Chemical Co.) to form a mud, the temperature of the mixture during spraying was about 30 ° C to 35 ° C. The mixture was allowed to react at 25 ° C for 2 hours, and then vacuum-dried at 25 ° C. The results are summarized in Table 32.袅 32 Compound weight of starting compound K4P2 0 7 H 2 0 2 H 2 0 2 H 2 0 2 Mole ratio of H 2 0 2% by weight Composition (g) (g) (%) 10 8 59 4.6 28.74 K4P2〇7 * 3.91H2〇2 10 9.5 59 5.4 33.70 K4P2O7 · 4.74H2〇2 10 11.0 59 6.4 36.30 K4P2〇7 * 5.6H2 02 10 17.5 59 10 41.64 K4P2〇7 · 6.93H2 02 10 21.0 59 12 41.48 K4P2〇7 · 6.99H2〇2 10 14.7 70 10 42.80 K4P2O7 · 7.26H2〇2 10 17.6 70 12 41.11 K4P2〇7 * 6.78H2〇2 76 This paper uses the Chinese National Standard (CNS &gt; A4 specification (210X297 mm) n ^ i I n In nn In In II / V (Please read the notes on the back before filling out this page) Order the seal of the Central Laboratories Bureau of the Ministry of Economic Affairs, Paiger Consumer Cooperative, A7 B7 V. Invention Explanation () Example 33 Synthesis of K2HPO4 by liquid spray synthesis. 3H2O2 The concentrated H2O2 solution was sprayed dropwise onto a solid potassium argon phosphate (PHP) (98❶ / ❶, Adrige Chemical Co., Ltd.). ). The mixture was allowed to react at 25 ° C for 1 hour, and then dried under vacuum at 25 ° C. The results are summarized in Table 33. 33 Starting compound complex K2HP04 H2O2 weight H2O2 concentration H2O2 / K2HPO4 mole ratio to H2O2 weight percentage composition (g) (g) (%) 5 4.97 59 3.0 38.04 K2HP. 4. 3. I5H2〇2 Example 34 Synthesis of KH2P〇4 · H2〇2 by liquid spray synthesis The concentrated solution of Η2 〇2 was sprayed dropwise on the solid potassium dihydrogen phosphate (PDHP) (98% , Adrige Chemical Co., Ltd.) The mixture was allowed to react at 25t for 1 hour, and then dried under vacuum at 25t. The results are summarized in Table 34. _ 77 This paper size applies Chinese National Standard (CNS &gt; A4 specification) (210X297 mm) &quot; ^ Order (Please read the precautions on the back before filling in this page)

AB 5. Description of the invention () 袅 34 Starting compound complex KH2P〇4 H2〇2 H20 concentration H202 / KH2P〇4 Molar ratio to H2 02 wt% (%) 5 6.23 59 3.0 20.18 ΚΗ2Ρ〇4 · H2〇2 Example 35 Synthesis of Ca2P2 07 by a liquid spray synthesis method. 3.42Η2 02 Spray a 59% solution of Η2202 on a calcium pyrophosphate solid (Adrige Chemical Company). The mixture was allowed to react at 25 ° C for 1 hour, and then dried under vacuum at 25 t. The results are summarized in Tables 35. (Please read the precautions on the reverse side before filling out this page) Order 35 Start compound complex 32 32 07 H202 Weight H2 02 Concentration H2 02 / Ca2p2 07 Molar ratio H2 02 Weight percentage composition (g) (g) (%) 5 10 59 8.82 31.41 Ca2P2 07 · 3.42H2 02 Printed by Shellfish Consumer Cooperative, Central Bureau of Standards, Ministry of Economic Affairs Example 36 Synthesis of Mg2P2O7 by liquid spray synthesis 4.6.202 Spraying a 59% solution of Η202 on magnesium pyrophosphate solids (Adrige Chemical Co.). The mixture was allowed to react at 25 ° C for 1 hour, after which it was dried under vacuum at 25 ° C. The results are summarized in Table 36. 78 This paper size applies to Chinese national standards (CNS &gt; A4 size (210X297 mm) A7 B7

Printed by the Consumers Cooperative of the Central Government Bureau of the Ministry of Economic Affairs I. 5. Description of the invention () 袅 36 Starting compound compound Mg2P2 0 7 H2 2 Weight H2 2 H2 0 2 / Mg 2 P 2 0 Molar ratio H 2 〇2 weight percentage composition (g) (g) (%) 5 10 59 7.72 41.28 Mg2p2〇7 · 4.60H2〇2 Although the phosphate complexes of several peroxides have been described above, they can be used to prepare stable complexes. The synthesis method is still relevant. The reaction between hydrogen peroxide solution and phosphate or concentrated phosphate is exothermic. The heat generated during the exothermic reaction will cause the decomposition of hydrogen peroxide. As a result, the complex becomes unstable or causes a lower ratio of peroxide to phosphate or concentrated phosphate in the resulting product. This problem is exacerbated when complexes are to be prepared in large quantities. Mud method In an attempt to control the thermal energy generated by the reaction of a hydrogen peroxide solution with a phosphate or concentrated scalefish salt, we discovered several synthetic methods. One of them is called the "mud-like method", which is named for the formation of a mud-like substance with water in dishate or concentrated scale acid. This is used to synthesize a mud-like compound of peroxide gas- The liquid-skull synthesis method includes mixing a desired inorganic compound with water to produce a soft mud. After the mud is allowed to cool, an aqueous solution of a peroxide gas is added. The mixture is dried to remove water, and the obtained hydrogen peroxide inorganic compound is obtained. The main advantage of this synthesis method is that although the inverse between the inorganic compounds and water 79 paper size is applicable to China National Standards (CNS) A4 specifications (210X297 mm) d 丨 (Please read the note on the back before you read (Fill in this page) Printed by A7 _______B7____, Shellfish Consumer Cooperative, Central Bureau of Standards, Ministry of Economic Affairs of the Ordering Department 5. Description of the invention () Should be an exothermic reaction 'but only a small amount of thermal energy is generated in the process of forming the peroxide inorganic complex' Therefore, the decomposition of hydrogen peroxide during the synthesis process can be avoided. Compared with the previous method, the decomposition of hydrogen peroxide due to the generation of a large amount of thermal energy is a major progress. The obtained hydrogen peroxide has no The crystals of the composite are extremely fine and more stable than those obtained by other methods, and lower concentrations of hydrogen peroxide can be used. In order not to be limited by any specific theory or mechanism of action, we believe that the formation of mud is the first step. Monohydrates are formed, after which the water molecules in these hydrates are replaced by peroxides to produce inorganic complexes of peroxides. Examples 37 and 38 provide examples of preparing two different peroxide phosphate complexes Method 37. Synthesizing Na4P2 07 · 2 · 3〇2202 in a mud-liquid synthesis method using argon peroxide of different concentrations in a slowly synthesized sodium pyrophosphate solid (98%, Adrige Chemical Co., Ltd.) Mix with deionized water to form a soft mud. Because it is an exothermic reaction, allow the mud to cool to room temperature. Then, mix different concentrations of hydrogen peroxide aqueous solution with the mud. At this temperature Does not rise. Allow the mixture to react at 25 ° C for 1 hour, and then vacuum-dry at 25 ° C. The vacuum-dried sample is further dried in an oven at 60 ° C to remove any residual moisture. The results are summarized in Table 37. (Please read note f on the back before filling this page}

, 1T &quot;! 80

A7 B7 V. Description of the invention Table 37 The weight of the starting compound complex SP H20, the weight of H2O2, the concentration of H2O2, h2o2 / sp, and the mole percentage of H2O2 (8) (g) (g) (%) 5 5 24.4 12 4.6 26.60 Na4p2〇7. 2.84H2〇2 5 5 9.8 30 4.6 27.92 Na4p207. 3.03H2〇2 5 5 2.4 59 2.2 17.16 Na4? 207 · 1.62H2〇2 5 5 3.0 59 2.8 19.67 Na4P2〇7 · 1.92H2〇2 5 5 3.2 59 3.2 24.43 He 4 卩 2〇7 2.53H2〇2 5 5 4 59 3.7 26.02 Na4P2〇7 · 2.75H2〇2 5 5 5 59 4.6 28.10 ^ a4 ^ 2®7 * 3.06H2〇2 50 * 50 50 59 4.6 27.40 Na4p2 ° 7 * 2.95H2〇2 200 * 200 200 59 4.6 28.31 Na4? 2〇7 '3.01H2〇2 * Sample was used in Example 3 of 8 Thermal stability test. --------- &gt; ------ ΐτ ------ ^ (Please read the note on the back before filling in this page) Central Standards Bureau of the Ministry of Economic Affairs w: printed by Industrial and Consumer Cooperatives Table 3 7 lists several advantages of using the mud-like method to prepare hydrogen peroxide composites: 1. When preparing sodium pyrophosphate triperoxy hydrate (Na4P207. 3H2O2), the rise of hydrogen peroxide The initial concentration does not have to be greater than 50%, and even a 12% nitrogen peroxide solution can be used for the preparation of the composite. 2. Can also be prepared with a large amount of starting materials (for example, 200g SP)

Na4P20.7 · 3H2O2, because there is no temperature rise during the mixing of the peroxide gas solution with the sp water mud. 3. Peroxide complexes with different compositions can be prepared by controlling the molar ratios of h2O2 to 81 &gt; in the starting materials. "Fan"] 3 8 K3p〇4. NH2〇2 was synthesized by a mud-liquid synthesis method. Slowly solid acid (97%, Aldrich Chemical Co., Ltd.) (PPT) and deionized water Stir to form a soft mud, and allow to cool to room temperature. Mix 59% aqueous hydrogen peroxide solution with the mud. The temperature does not rise at this time. The mixture was allowed to react at 25 t for 2 hours, after which it was dried under vacuum at 25 ° C. The results are summarized in Table 38. A liquid spray method (see Example 31) can be used to prepare potassium phosphate peroxides for use in the synthesis of most phosphate peroxide complexes. When a hydrogen peroxide solution is sprayed on the solid potassium phosphate, the reaction temperature immediately rises to about 80 ° C. This high temperature causes the decomposition of hydrogen peroxide and therefore reduces the amount of argon peroxide that can be combined with potassium phosphate. Obviously, the preparation of K3P04. 3H2 02 'mud is better than the liquid spray method. (Please read the notes on the back before filling this page.) Order the paper size printed by the Central Government Bureau of the Ministry of Economic Affairs, Shellfish Consumer Cooperatives. The paper size is applicable to the Chinese National Standard (CNS) A4 (210X297 mm). Shellfish Consumer Cooperatives Co., Ltd. Seal 83 A7 B7 V. Description of the invention () The starting compound complex K3P〇4 H20 h2 ° 2 H2 02 h2o2 / k3po H2〇2 The weight ratio of the molar ratio of 4 Weight percent (g) (g) (g) (%) 5 2 6.6 59 5.0 34.57 Κ3Ρ〇4 · 3.34Η2〇2 Example 39 Na4p207.3H2O2 heat synthesized by spray method and mud method Stability Store approximately 2 g of the composite sample in an uncovered (open, condition 1) or sealed (closed, correct 2) plastic container of 5 rU. Place the uncapped or sealed 疋 plastic bottle in a 23 ° C, 50% relative humidity (RH) incubator or 600 ° C oven. The content of h2O2 in the composite was measured. The results are summarized in Table 仞. t Paper size applies to China National Standard (CNS) A4 (210X297 mm)

A7 B7 V. Description of the invention (* Synthesis method storage conditions * Test conditions Η907 weight lw 2w 3w 4w 6w ⑴ 23 ° C, 50% RH 26.35 27.04 26.10 26.38 N / A 60t oven 25.76 24.57 20.39 21.22 N / A Spray method (2) 23eC, 50% RH 26.86 26.71 26.87 26.81 26.84 60 ° C oven 26.70 25.10 23.61 21.33 17.70 (1) 23TC.50% RH 26.85 26.93 26.73 26.64 26.98 60t oven 26.84 26.29 25.58 24.78 23.73 Slurry method (2) 23ΐ, 50% RH 27.15 27.04 26.98 26,72 27.33 60ΐOven 26.87 27.74 26.17 26.10 25.71 1 ^ — · ^^ 1 ^^ 1 m HI I / 1 &gt;-(Please read the notes on the back before filling (This page) Printed by Shellfish Consumer Cooperatives, Central Bureau of Standards, Ministry of Economic Affairs * Storage conditions: (1) Uncapped plastic bottles; (2) Sealed plastic bottles. Compare the results in Table 39 to '60%. The compound obtained by the spray method below has a lower degree of stability than the compound obtained by the mud method. However, the stability of the two is not much different at 23 ° C '50% relative humidity. Therefore, under unfavorable storage conditions, such as during normal transportation, mud The chemical method can provide some unexpected stability of the complex. The hydrate method is as described above. We are convinced that the mud method at the beginning of the reaction is to produce hydrates of monophosphate II or manganese phosphate. For many phosphates or concentrated In the case of phosphate compounds, hydrates can be manufactured using techniques well known in the art or are commercially available. Therefore, we tried to skip the formation of mud at the beginning of the mud method __ __84____ This paper applies to China National Ladder Standard (CNS) A4 ^ (2 丨 0X297 mm) 4 A7 B7 5. In the steps of the invention (), the peroxide compound is synthesized by the hydrate method. It is generally believed that in the mud method, it is 'hydrated' The water molecules in it are replaced by peroxides. The following example 40 provides an example of a hydrate synthesis method. FeW 40 uses the hydrate method to synthesize Na4P2 07. 3H2 0 2 will contain a pyrophosphate hook solid (99%, Aldrich Chemical Eight Division) mixed with 12%, 30% or 59% argon peroxide solution, and reacted at 25 t for 1 hour, and then at 25. (: Vacuum dried. Results are shown in Table 40. Therefore, the complex can be prepared by dropping water with less than 30% of peroxide gas. ^ I -----------: 1 ---- I%. · — 'F (Please read the notes on the back ^ | ^ before filling this page ”

25.87 Na4P207 -Na4P2〇7. (G) 24.5 (%) 12

Molar number comparison of H2〇2, Na4P2〇7 Printed by the Consumer Cooperatives of the Central Standards Bureau of the Ministry of Economic Affairs ν »4ρ2 ° 7 1〇2202 (g) 8.4 8.4

10.0 30 200 120 59 4.6 4.6 4.6 28.04 27.57

Na4P2〇7 · 2,9! Ϋ? °-quasi-kneading paper with a moderate ruler paper M 5 8 ί public 7 9 2 A7 B7 V. Description of the invention () Synthesis of sulfate perfluoride compound A complex of sulfate and peroxide was synthesized for use in the sterilization process described herein. Examples of detailed synthetic methods for two different sulfate complexes are provided in Examples 41 and 42. Example 41 Synthesis of Na2Si03 · 1.28H2O2 by liquid spray synthesis. A 59% solution of H2O2 was sprayed on a sodium sulfate solid (99%, Adrige Chemical Company). The mixture was allowed to react at 25 ° C for 1 hour, and then dried under vacuum at 25 ° C. The results are summarized in Table 41.袅 41 molar ratio of starting compound complex Na2S〇4 h2〇H2〇2 H2〇2, Na2S〇4 H2〇2 weight ratio (g) (g) 10 10 59 2.46 23.47 Na2S 〇4 · 1.28H2 〇2 Printed by the Shellfish Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs (please read the precautions on the back before filling out this page) 簏 Example 42 Synthesis of K2S04 by liquid spray synthesis. % Η 2 〇2 solution was sprayed on potassium sulfate solids (99%, Adrige Chemical Co., Ltd.). The mixture was allowed to react at 25 ° C for 1 hour, and then 86 paper standards were applied to Chinese storehouse standards ( CNS) Λ4 specification (210X297 mm) A7 B7 V. Description of the invention () Vacuum drying at 25t. The results are summarized in Table 42. Table 42 ---- one ---- starting compound complex K2S〇4 h2o H2〇2 H2〇2 / K2S〇4 H2 02 composition weight concentration mole ratio to weight percentage (g) ( g) (%) 10 7 59 2.12 23.47 K2S04. 〇.62H2〇2 (please read the note on the back before filling in this page) Central Government Bureau of the Ministry of Economic Affairs, Shellfish Consumer Cooperative, India, inverse acid overgas Synthesis of the complex We have also synthesized a complex of silicate and peroxide for the sterilization method described herein. Examples of detailed synthetic methods for two different silicate complexes are provided in Examples 43 and 44. Fan Gong 43 Synthesis of Na2Si〇3 by a mud-liquid method. NH2O2 A solid sodium silicate (Na2Si03, Adrige Chemical Co., Ltd.) was mixed with water to form a soft mud 'and cooled to Room temperature • Mix 12% aqueous solution of peroxide gas with mud. The temperature during mixing is approximately 30 ° C to 35 ° C. 〇 between. The mixture was allowed to react at 25C for 1 hour, and then vacuum-dried at 25 ° C. The results are summarized in Table 43. 87 This paper size applies to China National Standards (CNS M4 specifications (210X297 ^ * 7 printed by the Consumers' Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs A7 B7) 5. Description of the invention () 袅 43 Weight of the starting compound complex Na2Si〇3 h2o Weight of 〇2 Concentration of H2〇2 Molar number of H2〇2 / Na2Si〇3 Weight percentage composition of H2 02 (g) (g) (g) (%) 5 5 23.22 12 2.0 24.74 Na2Si〇3 · 1.18H2〇2 5 5 34.83 12 3.0 37.45 Na2Si〇3 · 2.15H2〇2 5 5 4645 12 4.0 37.64 Na2Si03 · 2.17H2〇2 Example 44 Synthesis of Na2Si3 07 by hydrate method. .68H2 02 will be 59 % H2O2 solution was sprayed on the sodium trisilicate hydrate solids (Na2Si3 07 · χΙί20, Adrige Chemical Co.). The mixture was allowed to react at 25 t for 1 hour, and then at 25 ° Vacuum drying was performed at C. The results are summarized in Table 4 4. 88 This paper size is applicable to China National Standard (CNS) A4 specifications (2 丨 0 &gt; &lt; 297 Gongguang) --------- t-- ----, order ------ fate — t (please read the notes on the back before filling this page)) 5. Description of the invention (A7 B7

Printed by the Central Plant Quarantine Bureau of the Ministry of Economic Affairs—Industrial and Consumer Cooperatives. Here we have shown that many kinds of inorganic hydrogen peroxide compounds can be prepared. We are convinced that the sterilization method disclosed here can successfully release thorium peroxide by using a large number of anion salts capable of forming hydrogen bonds, such as those which contain at least one oxygen or nitrogen atom. See the aforementioned Table 14 for examples of organic compounds and other inorganic compounds that can be used in conjunction with the method of the present invention. The release of fish mixture t meets oxygen. Your DSC curve in the previous example, such as Figure 6, was obtained in a cover plate with a hole under atmospheric pressure and reduced pressure. Since there is only one hole in the lid, an exothermic absorption peak can be seen on the DSC curve of the potassium oxalate peroxide complex at atmospheric pressure. Repeat this experiment at atmospheric pressure to determine that more hydrogen peroxide can be released in more open systems, as shown in Example 45. 89 The scale of private paper is applicable to China's family slope {CNS) A4 specification (210 X 297 mm) (Please read the note f on the back before filling this page) Order ^. -1 ^ 1 m In ...... A7 B7 Printed by the Central Laboratories of the Ministry of Economic Affairs, Shellfish Consumer Cooperative Co., Ltd. 5. Description of the invention () Example 45 Argon peroxide released from the oxalic acid-inhibited peroxide compound at atmospheric pressure. 2 The device with a two-hole sample tray with a sealed lid or an aluminum tray opened to the atmosphere, heated the potassium oxalate peroxide complex (K2C204.H202) at atmospheric pressure »Figure 10 shows the DSC curve obtained "If the lid is open, a small exothermic absorption peak appears after a large endothermic absorption peak on the curve, showing that only part of the hydrogen peroxide is released. When the plate is covered with a lid with two holes, a large exothermic absorption peak appears after a small endothermic absorption peak on the curve, which shows that some hydrogen peroxide is released, but most of the Argon peroxide has been decomposed. The results in Example 4 5 show that a large amount of hydrogen peroxide can be released in an open and uncovered plate instead of a lid with two holes. Therefore, in the rest of the experiments, 'we chose uncovered at atmospheric pressure. The plate was covered with a holed lid under reduced pressure, and the release of hydrogen peroxide from the composite was tested in the DSC curve. Figures 11 to 25 show the DSC curves of an inorganic compound, and Table 45 summarizes the reaction of the peroxide compound when heated in the DSC study. Figure 11A is the DSC curve of Na4P2 07. 2H2 0 2 and Na4P2 07 '3Η2 02 at 760 Torr. An endothermic absorption peak can be seen on 囷, which shows that argon peroxide is almost completely released. The 11th 囷 is a DSC curve of Na4P207. 4Η202 at 760 Torr. The figure shows two endothermic absorption peaks, showing a few 90% of hydrogen peroxide. Good paper size is applicable to China Solid Standard (CNS) A4 (210X 297 mm) ---------- Γ (please first (Read the note $ on the back and fill out this page)

-、 1T -line &gt; Printed by Shellfish Consumer Cooperative of Central Bureau of Quasi-Ministry of Economic Affairs A7 B7 V. Description of Invention () Almost completely released. Figure 12 is the DSC curve of Na3P04'5H202 at 76 ° C, 7 Torr and 0.35 Torr. The complex is based on the liquid mouth; It can be seen from the figure that a small exothermic absorption peak appears after an endothermic absorption peak, showing that part of the tritium argon is released at atmospheric pressure. But a wider endothermic effect under true &amp; shows that argon peroxide is almost completely released. The 13th @ is the DSC curve of Na2HP04. 1H202 and Na2Hp〇4 2H2 02 at 760 Torr. Both complexes showed an endothermic phenomenon on the Dsc curve, showing that they were almost completely released at atmospheric pressure.

Figure 14 is the DSC curve of Na5P3O10.H2O2 at 760 Torr. Several endothermic absorption peaks show a nearly complete release at atmospheric pressure. Figure 15 shows the DSC curve of K3PO4.3.34Η202 at 760 Torr, 7 Torr and 1.0 Torr. An endothermic absorption peak on the DSC curve at atmospheric pressure shows that most of the hydrogen peroxide has been decomposed at atmospheric pressure, but an endothermic absorption peak under vacuum 'before the exothermic absorption peak shows that some hydrogen peroxide is released under vacuum Out. Figure 16 is the DSC curve of K4P2O7. 7H2O2 at 760 Torr and 7 Torr. Based on the weight loss data obtained, the endothermic absorption peak and the exothermic absorption peak may cancel each other out in the temperature range of 140 ° C-180 ° C at atmospheric pressure. Therefore, the DSC curve shows that part of the hydrogen peroxide is released at atmospheric pressure. Several endothermic absorption peaks under vacuum show almost complete release in this case. The W threshold is K: 2HP〇4. 3.15H202 at 760 Torr and 7 Torr-; _______91___ _ This paper size applies Zhonggu National Standard Car (CNS) A4 ^ (210x297) (Please read the note f on the back before filling out this page) Order the Ace B7 Printing Policy of the Shellfish Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economy ) DSC curve. Based on the weight loss data obtained, the endothermic absorption peak and the exothermic absorption peak may cancel each other out in the temperature range of 140C-180C at atmospheric pressure. Therefore, the DSC curve shows that part of the hydrogen peroxide is released at atmospheric pressure. Several endothermic absorption peaks under vacuum show almost complete release in this case. Figure 18 shows the DSC curve of KH2PO4.H2O2 at 760 Torr. Two endothermic absorption peaks can be observed in the figure, showing almost complete release at atmospheric pressure. Figure M is the DSC curve of Na2C03.1.5H2O2 at 760 Torr and 7 Torr. The endothermic absorption fronts observed in the temperature range of 90 to 100t are caused by the release of hydrogen peroxide under atmospheric pressure and vacuum. The exothermic absorption seen at 150 ° C at atmospheric pressure is mostly due to the decomposition of argon peroxide. But 'this exothermic absorption peak turns into an endothermic absorption peak under vacuum, followed by a small exothermic absorption peak, showing that most of the hydrogen peroxide has been released. Figure 20 is the DSC curve of Ca2P20.7.3.42H2O2 at 760 Torr. The endothermic absorption peak in the figure shows that hydrogen peroxide is almost completely released. No. 21 is the DSC curve of Mg2p207. 4.6H202 at 760 Torr and 7 Torr. Immediately after the endothermic absorption peak, an exothermic absorption peak shows that part of the hydrogen peroxide is released at atmospheric pressure, but the larger endothermic absorption peak seen under vacuum shows that most of the argon peroxide has been removed. Release. No. 22 is Na2S04. 92 paper sizes of 1.28Η202 under 760 Torr, using China National Standard (CNS) Α4 size (210X297 mm) --------- install, ---- --- 1T ------ ^. ({Please read the note on the back before filling in this page) A7 B7 5. Description of the invention () DSC curve. The endothermic absorption peak in the figure shows that argon peroxide is almost completely released at atmospheric pressure. Figure 23 shows the DSC curve of K2S04.0.0.62H2O2 at 760 Torr. The endothermic absorption peak in tritium shows that hydrogen peroxide is almost completely released at atmospheric pressure. Figure 24 is the DSC curve of Na2Si〇3. 2.15H2O2 at 7600 Torr, 1 Torr and 0.5 Torr. The exothermic absorption peak shows that most of the hydrogen peroxide has been decomposed under vacuum and atmospheric pressure. The 25th line is the DSC curve of Na2Si30.7.68H2O2 at 760 Torr. The exothermic absorption peak shows that most of the hydrogen peroxide has been decomposed at atmospheric pressure. Table 4 5 summarizes the reaction of the peroxide complexes when heated in the DSC study. (Please read the note on the back before filling this page)-%

, 1T --i ··· Printed by the Bayer Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs 93 This paper size applies to the Chinese National Standard (CNS) A4 specification (2 丨 0X297 mm) V. Description of the invention () The reaction pattern of the 袅 45 compound when heated in DSC studies is numbered at 1 atmosphere (760 Torr) under vacuum K2C2 ° 4 '1H2 ° 2 endothermic + exothermic 10 Na4P207 NH2〇2 n = 2 , 3,4 Endothermic 11A and 11B Na3P〇4 * 5H2〇2 Endothermic + Exothermic 12 Na2HP〇4 · nH2〇2 n = 1, 2 Endothermic 13 Na ^ P ^ OjQ NH2O2 n = 1.2 Endothermic 14 K3PO4 * 3.34H2〇2 exothermic + exothermic 15 K4P2O7 · 7H2〇2 endothermic + exothermic 16 K2HPO4 · 3.15H2 02 endothermic + exothermic 17 KH2P〇4 · lH2 02 endothermic 18 Na2C03 · 1.5H2 02 exothermic + exothermic 19 匸 &amp; 2 卩 2〇7, 3,42H2〇2 endothermic endotherm 20 Mg2 ~ 2〇7 '4.60H2〇2 endothermic + exothermic endotherm 21 Na2S〇4 · 1.28H202 endothermic endotherm 22 K2S04 · 0.62H2 02 endothermic 23 Na2Si03 2.15H2〇2 exothermic 24 Na2Si3〇7 68. H2O2 exothermic exothermic 25 Efficiency test results The previous examples, such as Examples 17 and 18, show that with the support of the techniques described here and elsewhere, peroxide inorganic composites can be used for sterilization under vacuum. In order to show that these peroxide inorganic composites can also kill 94 at atmospheric pressure. This paper size applies the Chinese National Standard (CNS) A4 specification (210X297 mm) (Please read the precautions on the back before filling this page)-* Ministry of Economy A7 B7 printed by the Central Bureau of quasi-speciality Shellfish Consumer Cooperatives V. Description of the invention () bacteria, we tested the bactericidal efficiency of many compounds. Example 46A is a compound whose DSC curve has an endothermic absorption peak at atmospheric pressure, and sterilization results at atmospheric pressure and low temperature (S6 (TC). Example 46B is a DSC curve with both endothermic and exothermic absorption at atmospheric pressure ♦ The sterilization result of the compound 'at atmospheric pressure and low temperature (each 60X :). Example 46C is a compound whose DSC curve has an exothermic absorption peak at atmospheric pressure' at atmospheric pressure and low temperature (S60 ° C) Bactericidal results. Example 47 is a compound that has a DSC curve with only one endothermic absorption wave when heated at atmospheric pressure. Its sterilization result at one pressure. Example 48 is a DSC curve that has both endothermic and exothermic heating at one pressure. The compounds of absorption peaks have sterilization results at atmospheric pressure. As shown below, in these cases, using these compounds, even the compounds with only one exothermic absorption peak in their DSC curve can be effectively effective at atmospheric pressure. Sterilization • As mentioned above, it is generally believed that in some cases, the endothermic absorption peak may be masked by the exothermic absorption peak within the same temperature range. Cover, which can explain the sterilization test effect of the compound with only one exothermic absorption peak in the DSC curve.

Example 46A: KH2P04. H2O2 peroxide compound is used for sterilization (1 atmosphere and low temperature)

Assemble a self-service sterilization bag in the following manner: Place a 7.7 X steel blade on the surface on a sterilized petri dish (60 X 15 1111 «). Put 2g of KH2PO4 · H2O2 composite powder (containing 20.31% H2O2) into another __95. This paper scale is applicable to 0 national standard rate (0 ^) 8 4% ^ (21 () &gt; &lt; 297 mm) &quot; (Please read note f on the back before filling out this page) Order. 崠 'Printed by A7 B7, Shellfish Consumer Cooperative, Central Bureau of Standards, Ministry of Economic Affairs 5. Description of the invention () in a petri dish. Put two petri dishes together into a 1 () × 25 0 mni fungus bag made of TYVEKtm / MYLARTM. After the sterilization bag was sealed, it was placed at room temperature (about 23 ° C), 40 v c (in the incubator) and 60 ° C (in the oven) for different periods of time. The results are summarized in Table 4 6 A.

袅 46A temperature exposure time (positive reaction / phase ---- ~ 5 · total number of products, 1 hour 2 hours 4 hours 6 hours --- ^ 23 ° C (room temperature) + +--4 (TC + +--- • K 6 0 ° C +--

Example 46B: K2C2O4.H2O2 peroxide compound is used for sterilization (1 atmosphere and low temperature). A self-service sterilization bag is assembled in the following way: the surface containing 134 X 106 subtilis-like sprouts is run ( A stainless steel blade of Baci !! uS Var. Is placed on a sterilized petri dish (60 x 15 mm). 2g of KH2PO4 · h2〇2 composite powder (containing 14.1% H2〇2) is placed in another In a petri dish, put two culture shells together in a 100 × 25 mm sterilization bag made of MYLAR TM / μ YLART Μ. Seal the sterilization bags and place them at 40 ° C ( (In the incubator) and 60 (in the oven) for a different period of time. The results are summarized in Table 4 6 b. 96 This paper size applies to China National Standard (CNS) A4 (210X297 mm) (please First read the note $ on the back and fill in this page) Order A7 ____ B7 Factory I-____-V. Description of Invention ()

A 46B Temperature Sleep and sleep time (positive reaction / total number of samples) 8 hours 1 6 hours 2 4 hours 4 8 hours 7 2 hours 4 0eC N / A N / A + +-6 0 ° C +---

Example 4 6 C Use Na2C03.i 5H2O2 peroxide compound for sterilization (atmospheric pressure and low temperature) A self-service sterilization bag is assembled in the following way: 1.34 X 10 Bacillus subtilis να on the surface / *. 容 er)) 's stainless steel blade was placed on a sterilized culture ϋα (60 x 15 mm). 2 g of Na2co3. 15H202 complex powder (containing 27.78% H2O2'Foka Chemical Co., Ltd.) was put into another culture μ. The two culture μs were put together in a 100 × 25 mm sterilization bag made of M Y L AR T Μ / μ Y L AR T Μ. Seal the sterilization bag and place at 60 ° C (in an oven) for a different period of time. The results are summarized in Table 4 6 c. &Amp; J ------- 1T ------ ^ XMmi (Please read the precautions on the back before filling out this page) Printed by a consumer cooperative «. A 46C Temperature exposure time (positive reaction / total number of samples) 2 4 hours 4 8 hours 7 2 hours 6 0 ° 〇 +-* Example 47 97 This paper is in accordance with China National Standard (CNS) A4 specifications ( 210X297 ^^ 7 Printed by A7 _B7_, Shellfish Consumer Cooperative, Central Bureau of Standards, Ministry of Economic Affairs 5. Description of the invention () Use Na4P207. 3H2O2 peroxide compound for sterilization (at 1 atmosphere and elevated temperature of the compound) Na4p2 07 · 3H2 02 (weight percentage = 27%) was used in the device of the eighth circle. The parameters used in sterilization were as follows: sterilization inner chamber size = 6.25 &quot; X 6.25 &quot; X 7 &quot; (4.5 liters); Sterilization chamber temperature = 40 ° C; Sterilization chamber pressure = 760 Torr, heating temperature = 175-180. 〇. Each blade contains 1.5 x 1〇6 Vibrio bacillus spores. The concentration was used as the inoculation concentration. The results are summarized in Tables 47A and 47B. As shown in Table 47A, only the compound level of O.Olg can be used to achieve the effect of complete sterilization of the stainless steel blade located two inches above the heating device. In contrast, a blade that has been inoculated and located at the bottom of the sterilization chamber requires 0.3 g of the compound to achieve the full sterilization effect.

Table 47A Bactericidal effect (positive reaction / total number of samples) The sample is located on the top of the heating plate. The weight of the compound is 2/1 0 cycle * 2/1 5 ring 2/3 0 cycle O.Og 2/2 2/2 2 / 2 O.Olg 0/2 0/2 0/2 0.0 3 g 0/2 0/2 0/2 0 · 0 5 g 0/2 0/2 0/2: Cycle time = heating time (minutes) / Total exposure time (minutes)

Table 47B _________98 This paper size applies to Chinese National Standards (CNS &gt; A4 size (210X297mm) --------------- Order ------ 咮:-(please listen first Read the note on the back ^ ^ m · item and fill out this page again) A7 B7 V. Description of the Invention 2/3 0 cycle 0 · 0 g 2/2 2/2 2/2 0 · 1 g 2/2 2/2 2/2 〇. 2g 1/2 1/2 1/2 〇. 3g 0/2 0 / 2 0/2 0.5 g 0/2 0/2 0/2 (Please read the note on the back ^ ΡΙ · before filling out this page) *: Cycle time = heating time (minutes) / total exposure time (minutes)

Jfe case 48

1T 1 ** '— · Use K2C2O4. H2O2 peroxide compound for sterilization (at 1 atmosphere and elevated compound temperature) to [2〇2〇4.1 ^ 〇2 (weight percentage = 16.3%) was used in the device explained in 8. The parameters used for sterilization are shown in Example 47, but the heating temperature is changed to 155-160. (:. In this experiment, the blade inoculated with bacterial spores was placed above the heating plate. The results are summarized in Table 48. WC Industrial Consumption Cooperation by the Central Standards Bureau of the Ministry of Economic Affairs

A7 ____ B7 V. Description of the invention () 蛊 48 Sterilization effect (positive reaction / total number of samples) The sample is located at the two leaves above the heating plate. The weight of the compound is 2/10 cycles * 2/1 5 cycles 2/30 cycles 〇β β 2 / 2 2/2 2/2 0 · 〇1ε 1/2 1/2 0/2 —_0〇3g 0/2 0/2 0/2 0. 0 5 g 0/2 0/2 0/2 0. 1 g 0/2 0/2 0/2 0.2 g 0/2 0/2 0/2 (Please read the note on the back before filling in this page): Cycle time == heating time (minutes) / all exposed Time (minutes) When using potassium oxalate compound for sterilization, complete sterilization must be achieved with O.Olg and 30 minutes. In all three sterilization cycles, complete sterilization can be achieved using 0-03 g of the complex. In summary, hydrogen peroxide can be released from the complex at atmospheric pressure and room temperature. The release of hydrogen peroxide can be promoted by increasing the temperature and reducing the pressure. System for releasing radon gas from pergassed admixture The device used in Figs. 7A and 7B can be regarded as a system for releasing hydrogen peroxide vapor from an argon peroxide compound. This type of device can be used with a peroxide compound that forms a dish. However, we have found that the use of a powder-like compound allows the hydrogen peroxide vapor to be released more quickly and completely. With the 100th paper standard, the Chinese government has approved the "CNS &gt; A4 Specification (210X297 mm) &quot; &quot; &quot; &quot; &quot; Order -ff! A7 printed by Shellfish Consumer Cooperative, Central Bureau of Standards, Ministry of Economic Affairs ___— __B7_ V. Description of the invention () The composite powder is put into the device in the way described in 7A and 7B. However, another way to introduce the composite powder is to first put the composite powder on an adhesive tape with high temperature. on. For example, the high-temperature tape 9469 manufactured by 3M Company uses an ao0 adhesive produced by its company. The compound powder can be sprinkled on the adhesive and tape, and then placed in a sterilization chamber to release the hydrogen peroxide vapor. An example of another type of adhesive tape that can be used is 3845's adhesive tape 9585 made with A25 adhesive. Conclusion The scope of the present invention is not limited to the embodiments described above. Any embodiment that still retains the spirit of the present invention is regarded as still belonging to the scope of the present invention. However, the scope of the present invention is limited by the following patent application parks. (Please read the note on the back before filling in this I)-Order a piece of paper printed by the Central Standards Bureau of the Ministry of Economic Affairs and printed by the Shellfish Consumer Cooperative, a copy of the paper, a sample, a home, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, a country, and a country. 14 A4% 29

Claims (1)

Printing of A8 B8 C8 D8 by the Central Labor Bureau of the Ministry of Economic Affairs, Consumer Cooperatives ----------- ^^ __ VI. Application for patent scope 1. A device for sterilizing objects with argon peroxide, It contains at least one container for the sterilizing skeleton: and a source of oxygen vapor in communication with this container in the form of a stream. This source includes an inorganic compound that does not decompose to produce peroxide gas from acid, and The vapor from this source is brought into contact with the object to be sterilized for effective sterilization, wherein the complex is in a solid form. 2. The device according to item 1 of the patent application park, wherein the device includes a breathable obstruction. 3. The device according to item 丨 of the patent application scope, wherein the source of the hydrogen peroxide vapor is located in a sterilization container. 4. The device as described in item 1 of the scope of the patent application, wherein the source of the hydrogen peroxide vapor is located in a sealed enclosure communicating with the sterilization container in the form of a fluid "5. The device as described in item 4 of the patent application park There is still a valve between the enclosure and the sterilization container. 6. The device as described in item 1 of the scope of the patent application, further comprising a heating device capable of heating the rhenium peroxide inorganic compound. 7. The device described in the first paragraph of the patent application, wherein the hydrogen peroxide inorganic compound is located in a sterilization container, and the device further includes a usable 102 _ This paper is applicable to China Gujia Standard (CNS) ) A4 size (210X297 mm) --------- 'installation ------ ^ ------ line "(please read the note f on the back first and then fill in 5 ^ pages) Economy Printed by the Central Government Bureau of Labor and Consumer Cooperatives A8 B8 C8 D8 6. The heating device for heating the container is applied for patent application. 8. The device described in item 4 of the patent application application, which further includes a heating device Encapsulation heating device · 9. The device described in claim 4 of the patent application scope, further comprising a heating device capable of heating the composite. 10. The device described in claim 1 of the patent application scope, further comprising a A pump capable of evacuating a container "11, the device described in item 4 of the scope of patent application, further comprising a pump capable of evacuating the container and the enclosure. 12. As described in item 11 of the scope of patent application Device, in which the pump can not affect the sealed condition Under certain circumstances, the container is evacuated separately. 13. The device described in the scope of patent application item 4, further comprising a first pump capable of evacuating the container and a second flocculant capable of evacuating the enclosure. 14. The device described in Item 10 of the patent application patent garden also contains a first air extraction valve suitable for container air extraction. 103 This paper uses the Chinese National Standard (〇 ^) 8-4 (2 丨 0 father 297 mm) --------- install-(please read the note on the back and fill in the ¥ page) Order: _ 一 A8 B8 C8 D8 Patent Application Park 15 · The device described in item 丨 丨 of the scope of patent application, still includes a first extraction chamber suitable for container extraction, and a second extraction valve independent of the first extraction valve, which can independently evacuate the enclosure. Extraction valve. 16. The device described in item 1 of the patent application park further includes a mechanism capable of generating plasma. 17. The device described in item 16 of the scope of patent application, wherein the plasma is Generated in a container. 1 8 · The device as described in Item 1 of the patent application garden, wherein the compound is It is a complex formed by hydrogen peroxide and phosphate and concentrated phosphate. 1 9. The device as described in the first item of the patent application scope, wherein the complex is a complex formed by hydrogen peroxide and oxalate 20. The device according to item 1 of the scope of patent application, wherein the compound is a compound formed by hydrogen peroxide and carbonate. 21. The device according to item 1 of the scope of patent application, wherein the compound The compound is a compound formed by perfluorinated argon and sulfate. 2 The device according to item 1 of the scope of patent application, wherein the compound is a compound formed by hydrogen peroxide and silicate. 104 This paper uses China National Standards (CNS &gt; A4At grid (210X297)) ^ ------, tr ------ line-/ V {Please read the note f on the back before reading (Fill in this page) AS B8, C8, D8, and AS patents are applied for printing by the Central Gradient Bureau of the Ministry of Common Carriage, patent application scope 23. A method for sterilizing an object with hydrogen peroxide vapor, including contacting the object with an inorganic compound composed of argon peroxide The hydrogen peroxide vapor released in the object is used to achieve the effect of sterilizing the object, wherein the peroxide compound does not decompose to generate halogen acid. 24. The method according to item 23 of the scope of patent application, wherein the water content of the composite is less than 10%. 25. The method 所述 described in item 23 of the scope of patent application, wherein the method is performed at a temperature of 25 ° C or lower. 26. The method of claim 23, further comprising heating the composite to promote the release of vapor from the composite. 27. The method according to item 26 of the scope of patent application, wherein the heating is performed at a rate of at least 5 ° C per minute. --------- Oh! (Please read the precautions on the back before filling in the page)-% ?. The Central Government Bureau of the Ministry of Economic Affairs, the Ministry of Economic Affairs, and the Cooperative Cooperative Press 28. The method described in item 26 of the scope of patent application, where the heating is based on Perform at a rate of at least 10 ° C per minute. 29 The method according to item 26 of the patent application, wherein the heating is performed at a rate of at least 50 ° C per minute. 105 This paper is used in China® Standards (CNS) A4 specification (21〇 &lt; 297 mm) A8 B8 C8 D8, patent application scope 30. As described in item 26 of the scope of patent application Method, in which the heating is performed at a rate of at least 1,000 per minute "(please« read the note f on the back side and then fill in ^ page 31. The method described in item 26 of the scope of patent application, where the heating The process includes bringing the composite into contact with a preheated heating device. 3 2 · The method described in item 26 of the patent application, heating the composite to a temperature in excess of 86 ° C. 33. If applied The method described in item 23 of the patent, wherein the method is performed under atmospheric calendar. 34. The method described in item 23 of the application, wherein the method is performed under subatmospheric pressure. 3 5 · The method as described in item 34 of the scope of patent application, wherein the object to be sterilized is located in a sterilization container, and includes further vacuuming the container. Printing by the Consumers Cooperative of the Central Government Office of the Ministry of Economic Affairs 36. The method described in item 34, The pressure is lower than 50 Torr. 37. The method described in Item 36 of the patent application park, where the pressure is lower than 20 Torr. 106 This paper is applicable to China® National Standard ( CNS M4 Specifications () A8 B8 C8 D8 VI. Patent Application Range 38. The method described in item 37 of the patent application, where the pressure is less than 10 Torr »3 9 The method according to item 3, wherein the hydrogen peroxide vapor is released from the hydrogen peroxide inorganic compound located in the enclosure. 40. The method according to item 39 of the applied patent circle, wherein The energization in the enclosed object is not the same as the pressure in the sterilization container. 41. The method described in item 35 of the scope of patent application, wherein the step of vacuuming is performed before the object to be sterilized comes into contact with the vapor. 42 The method according to item 23 of the scope of patent application, further comprising generating a plasma around the object to be sterilized after introducing steam into the sterilization chamber. 43. The method according to item 42 of the patent application park, wherein Electropolymerization is produced in a sterilization container The Central Bureau of Standards, Ministry of Economic Affairs *: printed by the Industrial and Consumer Cooperatives It 44. The method described in item 42 of the Patent Application Group, wherein the plasma is generated outside the sterilization container and flows into the sterilization container to surround the sterilization container Package --------- Pack 1-/ \ (Please read the notes on the back before filling this page) Line 45. The method described in item 23 of the scope of patent application, the steps of contact Contains pressure pulses using this vapor. • In 107 A8 B8 C8 D8 Printed by the Central Consumers' Bureau of the Ministry of Economic Affairs, Consumer Work Cooperatives 6. Application for a scope of patent 46. The method described in item 23 of the scope of patent application, including the steps of contact It involves pumping its pressure down to or below atmospheric pressure. 47. The method according to item 23 of the scope of patent application, wherein the argon peroxide-free organic compound is a complex formed by argon peroxide and phosphate or concentrated phosphate. 48. The method according to item 47 of the patent application park, wherein the salts are potassium or sodium, magnesium or calcium. 49. The method according to item 48 of the scope of the patent application, wherein the inorganic complex is a complex formed by hydrogen peroxide and sodium pyrophosphate (N a4 P 2 07). 50. The method as described in item 49 of the scope of the patent application, wherein the inorganic complex has two or more europium peroxide molecules. 51. The method described in item 50 of the patent application, wherein the inorganic compound is a europium pyrophosphate triperoxide complex (Na4P207. 3H2 02). 52. The method described in item 48 of the scope of the patent application, in which the inorganic complex is a complex formed of thorium peroxide and sodium orthophosphate (Na3P〇4). 108 Chinese paper standard (CNS) ) A4 specification (2 丨 〇〆297mm) --------- Dream -------- if ------ line "(Please read the note $ on the back and fill it out first X) A8 B6 C8 D8 VI. Patent application range 5 3 · The method described in item 48 of the patent application scope, wherein the inorganic compound is a compound formed by oxygen peroxide and sodium hydrogen phosphate (Na2HP04) 54. The method as described in item 48 of the patent application, wherein the inorganic complex is a complex formed by hydrogen peroxide and trisodium pentaoxide (Na5P3100). 55_ 如The method described in Article 48 of the patent application, wherein the inorganic complex is a compound formed by hydrogen peroxide and potassium orthophosphate (K3PO). 56. The method described in Item 48 of the scope of patent application Among them, the inorganic compound is a compound formed by hydrogen peroxide and potassium pyrophosphate (K4P207). 57. For example, the 56th patent application park Said method, wherein the inorganic compound has two or more argon peroxide molecules. 5f. The method according to item 48 of the patented patent, wherein the inorganic compound is argon peroxide and potassium argon phosphate (K2HP〇4) complex formed "59_ The method described in the patent application park No. 48, wherein the inorganic complex is a complex formed by thorium peroxide and potassium dihydrogen phosphate (KH2PO4). 109 This paper size is in accordance with China National Standards (CNS) A4 (210X297 mm) --------- installation. I (Please read the note on the back before filling in the page-.1T. .Color · Printed by the Central Mongolian Bureau Shellfish Consumer Cooperative of the Ministry of Economic Affairs. Printed by the Central Government of the Ministry of Economic Affairs of the Central Laboratories of the Zhengong Consumer Cooperative «. A8 B8 C8 D8 VI. Application for a patent scope 60. The method described in item 59 of the patent scope, of which The inorganic compound is a hydrogen peroxide compound (KΗ2ρ〇4 · H2202) supporting potassium hydrogen phosphate. 61. The method described in item 47 of the scope of patent application, wherein the inorganic compound is hydrogen peroxide and coke Complex formed by calcium phosphate (Ca2P207) 6 2. 47. The method according to item 7, wherein the inorganic compound is a compound formed by hydrogen peroxide and magnesium pyrophosphate (Mg2P207). 6 3. The method according to item 23 of the patent application, Yuangu, Among them, the inorganic compound is a compound formed by hydrogen peroxide and oxalate. 64. The method described in item 63 of the scope of patent application, wherein the inorganic compound is argon peroxide and potassium oxalate (K2C2O4) The complex formed. 65. The method described in the patent application No. 64, wherein the inorganic complex is a hydrogen peroxide complex of potassium oxalate (k2c2o4.h2O2). 66. The method described in item 23 of the patent application, wherein the inorganic complex is a complex formed by hydrogen peroxide and carbonate. 67. The method described in item 66 of the scope of patent application, in which the carbonic acid category is 110 paper sizes applicable to China's "JIAJUN (CNS) A4 specification (210X297 mm)-^ 11 ^ Lian,-(please (Please read the notes on the back before filling out this page) Printed by the Central Government's Bureau of the Ministry of Economic Affairs, Consumer Cooperatives, A8 B8 C8 D8 —One -----------------1 &quot; ~ &gt;, The patent application scope is sodium salt, potassium salt or osmium salt. 68. The method according to item 67 of the patent application, wherein the inorganic complex is a complex formed of osmium oxide and sodium carbonate (Ma2C03). 69. The method as described in item 68 of the scope of the patent application, wherein the inorganic complex is a complex formed by sodium carbonate and 1.5 hydrogen peroxide, (Na2C0 · 1.5Η2〇2) β 70. The method according to item 67 of the application, wherein the inorganic compound is a compound formed by hydrogen peroxide and carbonic acid bell (K2co3). 71. The method according to item 67 of the application, wherein the inorganic complex is a complex formed by hydrogen peroxide and sodium bicarbonate (NaHC03). 72. The method described in item 67 of the scope of patent application, wherein the inorganic complex is a compound formed by hydrogen peroxide and potassium bicarbonate (KHCO3), 73. The method described in item 67 of the patent application park In the method, the inorganic compound is a compound formed by hydrogen peroxide and thorium carbonate (Rb2C03). 74. The method described in item 23 of the scope of the patent application, wherein the inorganic complex is a complex formed by hydrogen peroxide and sulfate. __ 111 This paper form A is suitable for Zhongguan household materials (CNS) A4 secret (210X297 mm) ------ ---------- installation ----- 1T ------ 0 (Please read the note on the back and fill in the β page first) A8 B8 C8 D8 Printed patent application scope of the Central Laboratories Bureau of the Ministry of Economic Affairs of the People's Republic of China 75. The method described in item 74 of the patent application Among them, the sulfates are sodium or treacherous salt. 76. The method described in item 75 of the scope of patent application, wherein the inorganic complex is a complex formed by hydrogen peroxide and sulfuric acid hook (Na2S04). 7 7. The method as described in item 75 of the scope of the patent application, wherein the inorganic complex is a complex formed of thorium peroxide and potassium sulfate (K2S04). 78. The method described in the patent application No. 23, wherein the inorganic complex is a complex formed by argon peroxide and silicate. 79. The method described in item 78 of the scope of patent application, wherein the silicic acid compound is flour salt. 80. The method according to item 79 of the scope of the patent application, wherein the inorganic complex is a complex formed by argon peroxide and sodium silicate (Na2Si03). 81. The method of claim 79, wherein the inorganic complex is a complex formed by argon peroxide and disodium trisilicate (Na2Si307). 8 2. The method according to item 23 of the patent application, wherein the inorganic compound can release hydrogen peroxide at atmospheric pressure and room temperature. Pack ------ 1T ------ ^ One (please read "Note f on the back page" page h) 112 Printed by the Central Standards Bureau of the Ministry of Economic Affairs, Shellfish Consumer Cooperatives A8 B8 C8 D8 ------------ &quot; t. Patent Application Park 83. For the method of applying for the scope of patent No. 23, hydrogen peroxide It is released at subatmospheric pressure. 84. The method of claim 23, wherein the step of contacting additionally includes argon peroxide released from the second source. 85. The second source of the method according to item 84 of the scope of patent application is the second hydrogen peroxide complex. 86. The method described in item 85 of the scope of the patent application, wherein the second hydrogen peroxide complex is an organic complex of hydrogen peroxide. 87. The method according to item 23 of the scope of the patent application, wherein the argon peroxide vapor is released from at least two different hydrogen peroxide compounds. 88. The method described in item 87 of the scope of the patent application 'wherein different erbium peroxide compounds are mixed by physical methods. 8 9. The method described in item 87 of the patent application, wherein The different hydrogen peroxide complexes are chemically mixed. 9 0. — A method for sterilizing an object with hydrogen peroxide vapor, comprising subjecting the object to an argon peroxide complex by heating sodium pyrophosphate (Na4P207) -------- ^- -Please read the note on the back before writing this page) A8 B8 C8 D8 Γ 'patent claim The argon peroxide vapour released is contacted to achieve the effect of sterilizing objects. 91. The method as described in claim 90 of the patent application, wherein the pyrophosphate (Na4P207) complex is a sodium pyrophosphate trihydrogen peroxide complex (Na4P207. 3H2O2). 92. The method described in item 90 of the scope of the patent application, wherein contacting the step snails is performed under atmospheric pressure. 93. The method as described in claim 90, wherein the composite is heated to a temperature of about 175 ° C to release steam. 94. The method described in Patent Application No. 90, which additionally includes placing the object to be sterilized in a container prior to the contacting step. 95. The method of claim 94, further comprising evacuating the container before the object to be sterilized comes into contact with the vapor, so when the vapor enters the container, the pressure inside the container is lower than 50 Torr. (Please read the note f on the back before filling out this page) Γ The Consumer Cooperative of the Central Government Bureau of the Ministry of Economic Affairs of the People's Republic of China, Yinna 96.—A method of sterilizing objects with argon peroxide, which includes at least: The sterilizing object is placed in a sterilization container; a hydrogen peroxide inorganic compound that does not decompose to produce acid and comes into contact with the container is placed in the container; and the container is allowed to stand at a temperature lower than 70 ° C for a period of time At this time, 114 paper sizes should be used, and the Chinese National Standard (CNS) A4 specification (210X297 mm) A8 ΒΒ C8 D8 六 、 Applicable patent Fangu ~ &quot; One is enough to release oxygen peroxide vapor from the compound And achieve an effective degree of sterilization of the object &lt; 97. The method as described in the patent application No. 96, wherein the container is a sterilization bag, a room or a room. 98. The method as described in claim 96, wherein the inorganic salt is a phosphate or concentrated phosphate. 99. The method according to item 96 of the patent application park, wherein the inorganic salt is oxalic acid M. 100. The method according to item 96 of the patent application park, wherein the inorganic salt is a carbonate. 101. The method according to item 96 of the patent application park, wherein the inorganic disc is a monosulfate. Printed by the Shellfish Consumer Cooperative of the Central Bureau of Economic Affairs of the Ministry of Economic Affairs (please read the note “$” on the back before filling out this page) Line 1 0 2. The method described in item 96 of the scope of patent application, in which this inorganic type It is a silicate. 1 0 3 · The method according to item 96 of the scope of patent application, wherein the container is allowed to stand at a pressure below one atmosphere. _ 115 This paper uses the Chinese national standard rate of 3L (CNS &gt; Λ4 grid (210X297 mm)) Printed by the central standard rate of the Ministry of Economic Affairs and Consumer Cooperatives A8 B8 C8 ______ 08 VI. Application for patent scope 104. If applying for patent The method according to item 96, wherein the container is allowed to stand at a temperature below 40 ° C. 105. The method according to item 96 of the patent application group, wherein the compound is heated with heat The temperature range is higher than 23 t to promote the release of hydrogen peroxide vapor. 106. The method described in item 96 of the scope of patent application, wherein the nitrogen peroxide compound is in the form of a powder. 10 7. The method according to item 96 of the patent application range, wherein the nitrogen peroxide compound is in the form of a tablet. 108. The method according to item 96 of the patent application range, wherein the nitrogen peroxide compound is 109. The method described in item 108 of the patent application park, wherein the enclosed item is located in a container. 110. The method described in item 108 of the scope of patent application, The character is in the container 111. The method described in item 110 of the patent application fan circle, wherein the enclosure is selectively separated by a valve and a container. _____116___ This paper is scaled to the Chinese national ladder? CNS) A4 specification ( 2 丨 0 X 297 public and ^ —---------- Jia, I (please read the note f on the back and fill in the &amp; page, 1T A8 B8 C8 D8 patent scope 12. If applied The method described in the scope of patent No. 11G, includes the method of removing the enclosure from the container. {Please read the note on the back before filling in this.) 13. If the method described in the scope of the patent, please The container therein is' sealed. '114. The method described in the scope of application for patents No. 1 13' where the container is sealed with a breathable substance. 15_ As described in the scope of application for patent 114 Method, where the breathable substance is a substance marketed under the Tiffany brand (T γ ve τ τ M). 1 1 6 · The method described in item 1 丨 4 of the scope of patent application, of which the breathable The substance is a CSR envelope. 117. The method described in item 114 of the patent application, wherein it is breathable The substance is paper. Oxygen printing by the Central Laboratories of the Ministry of Economic Affairs, Shellfish Consumer Cooperative, 1 1 8. The method described in Item 96 of the patent application park, additionally includes contacting the object to be sterilized with plasma. 1 1 9 The method as described in item 1-12 of the scope of patent application, which additionally includes the step of disposing the sealed object from the container, and then contacting the object to be sterilized with the plasma. &gt; Λ4 specification (210X297 mm) Printed by the Consumers' Cooperatives of the Central Standards Bureau of the Ministry of Economic Affairs «. A8 B8 C8 __D8 6. The scope of patent application is abrupt. 120.—A method of sterilizing an object outside and a narrow inner chamber with hydrogen peroxide, which at least includes: 'Connecting a container containing an argon peroxide compound to an inner chamber of the object, the argon peroxide compound is A compound that does not decompose to produce acid; puts the object to be sterilized in a sterilization container; 'evacuates the container; and contacts the inner chamber of the object with hydrogen peroxide vapor released from the thorium peroxide compound. 121. The method as described in claim 120, wherein the complex is a complex formed by phosphate or concentrated phosphate. 122. The method as described in claim 120, wherein the complex is a complex formed from oxalate. 123. The method as described in claim 120, wherein the complex is a complex formed by carbonate. 124. The method described in item 120 of the patent application, wherein the complex is a complex formed by sulfate. 125. The method described in item 120 of the patent application fan circle, in which this compound _ 118 sheets of paper / Ut used in HH homes (CNS) (21GX297 mm) 'a (please read the note f on the back first) Please fill in this item I) and set the seal of the shelling consumer cooperative of the Central Bureau of Economic Affairs of the Ministry of Economic Affairs *. A8 B8 C8 D8 6. The scope of patent application is a compound formed by silicate. 126. The method described in item 120 of the patent application scope, further comprising the step of contacting the exterior of the object to be sterilized with a second source of bactericide. 127. The method described in item 126 of the scope of patent application, wherein The second source of biocide is the same hydrogen peroxide complex contained in the container. 128. The method described in item 126 of the patent application, wherein the second source of the fungicide is an argon peroxide compound different from that contained in the container. 129. The method described in item 126 of the scope of the patent application, the second of which is--the source of the fungicide is argon peroxide. 130. According to the method described in No. 126 of the applied patent, the second source of fungicide applied is dioxide. 131. The method described in item 120 of the scope of patent application, additionally including contacting the object to be sterilized with the plasma. 132. The device described in item 1 of the patent application, wherein the pressure of the container is less than 50 Torr (Torr), and the temperature of this peroxide gas inorganic compound is higher than 8 6 ° C »119 This paper size is in accordance with China National Standard (CNS) A4 specification (210X297 mm) (Please read the note on the back first $ Item, please fill in this page again) Order · Line 'A8 B8 C8 D8_____ ----------- Six, apply for a patent Fangu 133 · The device described in the patent application Fanjie Item 132 the pressure is lower than the 〇 Torr · 134. The device described in item 132 of the patent application 'where the pressure is lower than 10 Torr. 135. The source of the hydrogen peroxide complex in the device as described in the scope of the patent application No. 132 is located in a container. 136. The device described in item 132 of the patent application circle further includes an enclosure outside the container containing the compound, and a channel that allows fluid to communicate between the container and the enclosure, so that the compound The released steam can enter the container along this channel to achieve the sterilization effect β 137. The device described in the scope of the patent application No. 132, wherein the inorganic compound of argon peroxide is sodium carbonate, potassium pyrophosphate or oxalic acid A complex formed by potassium. Printed by the Shell Standard Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs (please read the note on the back before filling in this page) 138. The device described in the patent application Fan Yuan Item 132 further includes a heating device located in the container The compound is placed on the heating device and heated to promote the release of steam from the compound. 139. The device described in the patent application park No. 138, where the heating device is in contact with the compound. It has been preheated before · 120 paper sizes are applicable to China National Standards (CNS) Α4 standard (210X297 mm) '' Applying for a patent for the park Fan Ke, the Central Gradient Bureau of the Ministry of Economic Affairs, Shellfish Consumer Cooperative, Ltd. 140. The device described in item 132 of the patent application, further includes a true pump for communicating with the container to evacuate the container. 141. The decoration according to item 132 of the scope of patent application, further comprising an electrode capable of generating a plasma around the object to be sterilized. 142. The device according to item 141 of the patent application, wherein the electrodes are located in a container. 1 4 3. The device described in Item 141 of the patent application park, wherein the electrodes are scattered in a container and the plasma generated by the electrode can flow around the object. 144. The device in the device described in item 132 of the patent application is in a solid form. 145. The method described in item 120 of the patent application park, additionally includes the step of reducing the pressure of the container before letting it stand ® ° (Please read the note on the back before filling this page} it 1 ^ 1 m · Order · · 121 The size of the paper is applicable to China National Standard (CNS) Α4 specification (21 〇 × 297 mm)