TW370531B - Novel thymidylate analogs and uses thereof - Google Patents

Novel thymidylate analogs and uses thereof

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Publication number
TW370531B
TW370531B TW085104440A TW85104440A TW370531B TW 370531 B TW370531 B TW 370531B TW 085104440 A TW085104440 A TW 085104440A TW 85104440 A TW85104440 A TW 85104440A TW 370531 B TW370531 B TW 370531B
Authority
TW
Taiwan
Prior art keywords
group
analogs
hiv
thymidylate analogs
following formula
Prior art date
Application number
TW085104440A
Other languages
Chinese (zh)
Inventor
Ji-Ru Hu
Gholam H Hakimelahi
Shwu-Chen Tsay
Original Assignee
Nat Science Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Science Council filed Critical Nat Science Council
Priority to TW085104440A priority Critical patent/TW370531B/en
Application granted granted Critical
Publication of TW370531B publication Critical patent/TW370531B/en

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Abstract

The present invention provides a group of thymidylate analogs having a structure shown in the following formula I, wherein R1 is a hydrogen, a cyano group (-CN), a halogen or a tri-nitrogen group (N3); R2 is a hydroxy group, aminoester group (-NHR4COOR5, wherein R4 is a C1-C4 ethylene and R5 is a C1-C4 alkyl group); and R3 is a hydroxy group or a thymidyl group having a structure of the following formula. The present invention also discloses an anti-HIV (human immunodeficiency virus, HIV) medical composition containing novel thymidylate analogs of formula I as effective constituents.
TW085104440A 1996-04-13 1996-04-13 Novel thymidylate analogs and uses thereof TW370531B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW085104440A TW370531B (en) 1996-04-13 1996-04-13 Novel thymidylate analogs and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW085104440A TW370531B (en) 1996-04-13 1996-04-13 Novel thymidylate analogs and uses thereof

Publications (1)

Publication Number Publication Date
TW370531B true TW370531B (en) 1999-09-21

Family

ID=57941471

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085104440A TW370531B (en) 1996-04-13 1996-04-13 Novel thymidylate analogs and uses thereof

Country Status (1)

Country Link
TW (1) TW370531B (en)

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