TW369540B - New adenylate analogs derivatives and usage thereof - Google Patents
New adenylate analogs derivatives and usage thereofInfo
- Publication number
- TW369540B TW369540B TW085104442A TW85104442A TW369540B TW 369540 B TW369540 B TW 369540B TW 085104442 A TW085104442 A TW 085104442A TW 85104442 A TW85104442 A TW 85104442A TW 369540 B TW369540 B TW 369540B
- Authority
- TW
- Taiwan
- Prior art keywords
- new
- adenylate
- usage
- adenylate analogs
- hydrocarbon radical
- Prior art date
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A kind of adenylate analogs derivatives with the provided formula (I) in which R1 represents hydrocarbon radical, C1-C4 alkoxyl or -NHR3COOR4 amino ester wherein R3 is C1-C4 tetraalkyl and R4 is C1-C4 alkyl; and, R2 is hydrocarbon radical -O+NH4 aminoxyl or the formula (II) indicated in claim 1. The invention provides the new adenylate analogs which can be used as effective component for antiherpes virus via the combination therapy by linking the acyclic adenosine and arabinoside with phosphonate. The cellular toxicity is rather low especially with better lipophilicity and water-solubility of diadenylate phosphoramidate so as to increase the antibacteria activity.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW085104442A TW369540B (en) | 1996-04-13 | 1996-04-13 | New adenylate analogs derivatives and usage thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW085104442A TW369540B (en) | 1996-04-13 | 1996-04-13 | New adenylate analogs derivatives and usage thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
TW369540B true TW369540B (en) | 1999-09-11 |
Family
ID=57941403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW085104442A TW369540B (en) | 1996-04-13 | 1996-04-13 | New adenylate analogs derivatives and usage thereof |
Country Status (1)
Country | Link |
---|---|
TW (1) | TW369540B (en) |
-
1996
- 1996-04-13 TW TW085104442A patent/TW369540B/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK4A | Expiration of patent term of an invention patent |