TW360651B - Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics and intermediates for their preparation - Google Patents

Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics and intermediates for their preparation

Info

Publication number
TW360651B
TW360651B TW081108831A TW81108831A TW360651B TW 360651 B TW360651 B TW 360651B TW 081108831 A TW081108831 A TW 081108831A TW 81108831 A TW81108831 A TW 81108831A TW 360651 B TW360651 B TW 360651B
Authority
TW
Taiwan
Prior art keywords
compounds
useful
heteroarylpiperidines
pyrrolidines
piperazines
Prior art date
Application number
TW081108831A
Other languages
Chinese (zh)
Inventor
Joseph T Strupczewski
Grover C Helsley
Yulin Chiang
Kenneth J Bordeau
Edward J Glamkowski
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of TW360651B publication Critical patent/TW360651B/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents, the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal. A compound of the formula, wherein X is -O- or -S-; p is 1 or 2; Y is hydrogen, or halogen; Q1 is selected from the following groups: (a) to (c); in which Z is (groups); and Y2 is selected from the following: (group 1) in which R1 is unsubstituted -CH2-CH=CH-CH2-; (group 2) in which R1 is -(CH2)n- in which n is an integer of 2 to 5; and R3 is hydrogen or -OCH3; (groups 3 to 13).
TW081108831A 1991-11-05 1992-11-05 Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics and intermediates for their preparation TW360651B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78826991A 1991-11-05 1991-11-05

Publications (1)

Publication Number Publication Date
TW360651B true TW360651B (en) 1999-06-11

Family

ID=57940673

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081108831A TW360651B (en) 1991-11-05 1992-11-05 Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics and intermediates for their preparation

Country Status (1)

Country Link
TW (1) TW360651B (en)

Similar Documents

Publication Publication Date Title
CA2121253A1 (en) Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgetics
IT1100945B (en) DIHYDROXYOTHYDROPHENANTRENIC COMPOUNDS WITH ANALGESIC ACTION AND THEIR INTERMEDIATES
YU94792A (en) THREE-SUBSTITUTED TETRAHYDROFURAN ANTIGLIVIC AGENTS
IL110151A0 (en) Amide and urea derivatives and pharmaceutical compositions containing the same
EP0324387A3 (en) Composition for treatment of ischemic disorder in organs
EP0632031A4 (en)
IL106307A (en) Isoxazole derivatives for the treatment of irritable bowel syndrome
PL309874A1 (en) Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
HUT67259A (en) 5-amino-8-methyl-7-pyrrolidinyl-quinoline-3-carboxylic acid derivatives and pharmaceutical compositions containing them
DE3875346T2 (en) COMPOSITIONS CONTAINING AZACYCLOAL CHANES SUBSTITUTED WITH 1-OXO OR THIOCARBON.
TW355183B (en) Substituted benzenesulfonylureas having cardiovascular activity for their preparation, and pharmaceutical compositions containing them
EP0397613A3 (en) Pharmacologically active aminoimidazopyridines
TW360651B (en) Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics and intermediates for their preparation
AU625238B2 (en) Anti-psychotic piperidylbenzimidazole compounds
FI95247C (en) Process for the preparation of 1,3-thiazolidines -carbonylcarboxamides for use as medicaments
ES488387A1 (en) Condensed derivatives of pyrrolidine or piperidine, process for their preparation and composition containing them.
DE69019423T2 (en) Epoxysuccinic acid derivatives useful as specific inhibitors of Cathepsin B.
IL150100A0 (en) Pharmaceutical compositions containing fused cyclic compounds
TW353071B (en) Chromene compounds with neutroleptic activity, their preparation and pharmaceutical compositions
TW349949B (en) New imidazole derivatives, preparation process, intermediates obtained, use as medicaments, pharmaceutical compositions and new use
JO1674B1 (en) Substituted benzimidazoles, process for their preparation and their pharmaceutical use