TW360651B - Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics and intermediates for their preparation
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Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics and intermediates for their preparation
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
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Plural Heterocyclic Compounds
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Abstract
Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents, the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal. A compound of the formula, wherein X is -O- or -S-; p is 1 or 2; Y is hydrogen, or halogen; Q1 is selected from the following groups: (a) to (c); in which Z is (groups); and Y2 is selected from the following: (group 1) in which R1 is unsubstituted -CH2-CH=CH-CH2-; (group 2) in which R1 is -(CH2)n- in which n is an integer of 2 to 5; and R3 is hydrogen or -OCH3; (groups 3 to 13).
TW081108831A1991-11-051992-11-05Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics and intermediates for their preparation
TW360651B
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