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Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
A new preparation of vitamin K1 and K2 as shown below by reaction of 3-substituted isobenzofuranones (1) with 1-substituted(E)-1-phenylsulfonylpropenes(2) is disclosed. The reactants (1) and (2) are known or readily prepared. The present invention allows the combination of three-step reaction in one pot, the economic use of alkylating reagent, and the high retention of side chain configuration under basic conditions.
TW082109867A1993-11-241993-11-24Preparation of vitamin K
TW327168B
(en)