TW306865B - - Google Patents

Description

-G, r A7 B7 5. Description of the invention (1) The present invention relates to novel oxime derivatives, several methods for their preparation and their use as pesticidal agents. It is known that various substituted substituted oximino- and alkoxymethylenevinylamines have bactericidal properties (details such as EP-A 398 692, 468 775, DE-A 40 30 038 and WO-A 92/13 830). However, the activity of these prior art compounds is not completely satisfactory in all fields of application, especially when using low application rates and concentrations. The present invention has discovered novel oxime derivatives of formula (I)

.X Άγ ο—Υ (please read the precautions on the back before filling out this page) • Ε, where Ar is printed by the Beigong Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs, which represents the substituted aryl groups or aza groups selected by the representatives respectively Radicals, representing a direct bond, or abene_1,1_diyl, which has an R1 radical at the 2-position or 2_ 气 杂 _ 1_ 女 _ 1,1_ 一 基 'at the 2-position With R2 group, or represents 3-aza-propene-2,3-diyl group, which has R group at 3-position and R1 group at bu position 'or represents 1-aza-1-propene-2 , 3-diyl, which has an R2 group at the 1-position, or represents 1,3-dioxa-1-propene-2,3-diyl, which has an R group at the 3-position and a group at the Bu position , Or on behalf of the optionally substituted imino group (" azamethylene ", N-R3), on behalf of the environmental group, -The size of this paper is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm ) A7 B7 printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economy V. Description of invention (2)

Ri stands for hydrogen, by element, cyano, or optionally substituted alkyl, alkyloxy, alkylthio, alkylamine or dialkylamine, R2 represents hydrogen, amine, nitrogen, or separately selected Ground substituted alkyl, alkoxy, alkylamino or dialkylamino, and R3 represents hydrogen, cyano, or optionally substituted alkyl, alkenyl, alkyl, cycloalkyl or cycloalkyl Gyl group, G represents oxygen, or represents a diyl group, a bisdiyl group, an oxadienediyl group, or a diyl group, which is selectively selected from the group consisting of a prime group, a meridian group, an alkyl group, a substituted alkyl group, and a cycloalkyl group Replace or represent one of the following groups: ~ Q ~ CQ-, " CQ-Q- / -CH2-Q-; -Q-CH2- # -CQ, Q-CH2_, CH2-Q-CQ-,- Q, CQ-CH2 ·, -Q-CQ-Q-CH2-, -Ν = Ν-, _S (0) n-, -CH2-S (0) n-, -CQ-, -S (0) n -CH2-, -C (R4): N-0-, -C (R4) = N-0-CH2-, -N (R5)-, -CQ-N (R5)-, -N (R5)- CQ-, -Q-CQ-N (R5)-, -N = C (R4) -Q-CH2-, -CH2-0-N = C (R4)-, -N (R5) -CQ-Q- , -CQ-N (R5) -CQ-Q-, -N (R5) -CQ-Q-CH2-, -CQ-CH2- or -N = NC (R4) = N-0-, where n represents 0 , 1 or 2, Q represents oxygen or sulfur, R4 represents hydrogen, cyano, or optionally substituted alkyl, Oxygen, alkylthio, alkylamino, dialkylamino or cycloalkyl, and R5 represents hydrogen, hydrogen, cyano, or optionally substituted alkyl, alkyloxy or cycloalkyl, X Represents -0X1, -SX1, -S0X1, -S〇2 X1, or -NX2 X3, the paper size is applicable to the Chinese National Standard (CNS) A4 specification (210X 297 mm) (please read the precautions on the back before writing this book page)

, 1T f!

Where X1, X2, and X3 independently represent radium, or optionally substituted alkyl, cycloalkyl, aryl, or heterocyclic group, or X2 and X3 together with a nitrogen atom form a selectively substituted heterocyclic ring , Y 1 represents hydrogen, or optionally substituted alkyl, cycloalkyl, aryl, or heterocyclic group, and 1 represents respectively optionally substituted alkyl, alkenyl, alkyl, environmental, aryl , Aryloxy, arylthio, arylamino, heterocyclic, androgen epoxy, heterocyclic thio or heterocyclic amine. Furthermore, the present invention found that the novel oxime derivative of formula (I) can be prepared by the following method: a) The thiomeryl derivative of formula (Π), G, ArE, c, (s) x1

II S (II), where

Ar, E, G, XI and z have the aforementioned definitions, and the hydroxylamine derivative of formula (1Π) Η 2 Ν-0-Υ 1 () Printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economy where Υ1 has the aforementioned definitions, or The acid addition salt, if appropriate in the presence of a diluent and if appropriate in the presence of a reaction auxiliary, is reacted; or the paper size is applicable to ϋ® Jiaxian (CNS) Α4 threat (2lGx297 public) S06805 A7 V. DESCRIPTION OF THE INVENTION (4b) The amide derivatives of formula (IV) Z'G, Ar-ε / Νηχ3 · c II s (IV), t Ar, E, G, x3 and 2 have the aforementioned definitions, according to the conventional methods Add to call and ride the formula (_imino derivative.G,

NX I S Aik (IVa), where

Ar, E, G, X3, and z have the aforementioned definitions, and Aik represents an alkyl group, preferably a methyl group, if appropriate, without separation, it is added to the spicy amine derivative of formula (1) or its acid, if appropriate In the presence of a diluent and if appropriate in the presence of a reaction aid, carry out the reaction; or c) Print the formula (V) acetamide derivative Ministry of Economic Affairs Central Standards Bureau employee consumer cooperative

z, G, ArE, c 'II S

NH-OY (V), where Ar, E, G, Υ 1 and Z have the aforementioned definitions, are emulsified according to the conventional method, and then the obtained formula (Va) oxime. G p N ^ O-YZ〆, Ar, E, c 々 where 'Aik Ar, E, G, If 1 and Aik have the aforementioned definitions, (va) This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 male thin) A7 V. Invention description (v / If appropriate without separation, the amine of formula (VI) where HM2X3 (VI) X2 and X3 have the pre-definition definition, please read the precautions on it before proceeding if appropriate in the presence of diluent. Where X = S0X1 Or the compound of formula (I) of S02 XI is prepared by oxidizing the compound of formula (I) where X = SX1 (for example by oxidation with radon or organic peracid) according to the usual practice. Finally, the formula was found The novel oxime derivatives of (I) show extremely strong fungicidal activity. If appropriate, the compounds according to the invention may exist in the form of mixtures of different possible isomeric forms, especially in the form of E and Z isomers Exists, but, if appropriate, can exist in the form of optical isomers and diastereomers The request in this case is any mixture of E and 2 isomers and all other possible isomers. The present invention preferably relates to compounds of formula (I) in which the symbols have the following definitions: Employees of the Central Bureau of Standards of the Ministry of Economic Affairs Printed by consumer cooperatives

Ar represents optionally substituted phenylene or azulenyl, or 5 or 6 ring members (at least one of which represents oxygen, bromine or nitrogen and, if appropriate, one or two other ring members represent gas) Heteroaryl groups, possible substituents are preferably selected from the following series: _ element, cyano group, aceryl group, amine group, sulfonyl group, methylacetate, carboxyl, aminomethylacetate, thioamine Methyl group, linear or branched alkyl group, alkyloxy group, alkylthio group, alkylsulfenyl group or alkylsulfonyl group (which have 1 to 6 carbon atoms>, respectively, straight The basic paper scale of chain or branched ene is applicable to China National Standard (CNS) Α4 specification (210X297 mm) B7 ----------- ---------- V. Description of the invention (6), alkenyloxy or dioxy (which have 2 to 6 carbon atoms, respectively), straight-chain or branched, substituted alkyl, alkoxy substituted, substituted alkylthio, halogenated alkyl Sulfenyl or sulfonyl sulfonyl (which has 1 to 6 carbon atoms and 1 to 13 same or different from prime atoms, respectively), straight-chain or branched _-alkenyl or carbene Oxygen (which have 2 to 6 carbons respectively The same as or different from 1 to 13 is the same or different from the atom atom>, respectively, straight-chain or branched alkylamine group, dialkylamine group, alkylmeryl group, alkylcarbonyloxy group, alkyloxycarbonyl group, alkyl group Sulfonyloxy, m-iminoalkyl or oximinoyl (which has 1 to 6 carbon atoms in each alkyl group respectively), or represents a second-elongated alkyl or alkyl group Oxygen groups, which have 1 to 6 carbon atoms, respectively, and which are optionally mono- or poly-substituted with the same or different substituents selected from the group consisting of: 1 and 4 by element and / or linear or branched The alkyl group of the carbon atom and / or the straight chain or branched group has 1 to 4 carbon atoms and 1 to 9 are the same or different from the basic atom atom group, E represents a direct bond or one of the following groups:

The Beigong Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs prints where Y represents oxygen, sulfur, methylene (CH2) or alkylimine (NR), R represents an alkyl group with 1 to 6 carbon atoms, and R1 represents hydrogen, Halogen, cyano, or on behalf of alkoxy, alkoxy, and burnt paper. The standard is printed using the Chinese National Standard (CNS) A4 (210Χ297 mm). The A7 _______B7 ______ is printed by the Beigong Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economy. Description (7) Thio, emulsyl or dialkylamino, which have 1 to 6 carbon atoms in the alkyl portion and are optionally substituted by a prime, cyano or C 1 _ C4 -alkoxy, respectively, R2 Represents hydrogen, amine, cyano, or represents alkyl, alkyloxy, alkylamino, or dialkylamino, which has 1 to 6 carbon atoms in the alkyl group and is selectively selected from prime, mono, or Cl _C4, respectively -Substituted by alkyloxy, and R 3 represents hydrogen, cyano, or represents alkyl, alkenyl, or alkyl, each having up to 6 carbon atoms, and is selectively selected via prime, cyano, or Ci-C4-oxo Substituted by a group, or represents a cycloalkyl group or a cycloalkyl group, which has 3 to 6 broken atoms in the cycloalkyl group and, if appropriate , With 1 to 4 carbon atoms in the alkyl group, and they are optionally substituted by prime, amino, carboxy, C 1 _C4 -alkyl or C! -C4 -alkyloxy-carbonyl, G represents oxygen, or Represents alkanediyl, alkenediyl, oxadienediyl and alkadiyl, each of which has up to 4 carbon atoms and which are selectively substituted by prime, meridian, Ci_C4 -alkyl, Ci_〇4- Substitution or (; 3-cycloalkyl group substituted, or represents one of the following groups: CQ-Q-, -CH2-Q-; -Q-CH2-, -CQ-Q-CH2- -Q-CQ- CH2-, -Q-CQ-Q-CH2-, -NsN-, -S (0) n- -Q-CQ- / -ch2-q-cQ -CH2-S (〇) n_, -C (R4) eN-〇-CH2- -Q-cq-n (Rs)-'—- —2 N (R5) -CQ-Q- ^ -CQ-N (R5) -CQ-Q-, -N (R5)- CQ-Q-CH2 1 -Nsn-c (R4) »n-〇-, where -CQ-, -S (〇) n -N (R5) -r -N = C (R4) -Q-CH2 -C (R4) = N-0-, -CQ-N (R5)-, -N (R5) -CQ-, (please read the precautions on the back first and fill in this page)

CH 2 -CH--0-N = C (R4)

-CQ-CH '2' This paper scale is applicable to the A4 size printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economy A7 B7 V. Description of invention (8) η represents 0, 1 or 2, Q represents oxygen or sulfur, R4 represents hydrogen, Cyano, or represents alkyl, alkoxy, alkylthio, alkylamino or dialkylamino, which has 1 to 6 carbon atoms in the alkyl group and optionally via cyano, cyano or C 1 -C 4 -Alkoxy is substituted, or represents a cycloalkyl having 3 to 6 carbon atoms, which is optionally substituted by halogen, gas, sulfonyl, Cl-C4_alkyl or Cl-C4 ~ alkyloxy-carbonyl , And R5 represents hydrogen, alkyl, cyano, or represents an alkyl group having 1 to 6 carbon atoms, which is optionally substituted by a prime, cyano group, or C 1 -C 4 -alkyloxy group, or represents a group having 3 to 6 carbon atom cyclic alkyl group, the choice of which is also substituted by halogen, cyano, hydroxy, Ci < 4-alkyl or Ci-C4-oxo-carbonyl, X represents -OX 1, -SX 1, -SOX 1, -SO 2 X 1 or -NX2 X3, wherein χι, X2 and X3 independently represent hydrogen, or represent an alkyl group having 1 to 8 carbon atoms, which is optionally selected from the group consisting of prime, cyano, m, Amino group, Ci 44 _ alkyloxy group, Ci -C4 _ Burnt sulfur group, Ci -C4 -hyunyl sub-branched group or Cl -C4 -burned group continued brewing group (which are optionally substituted by element), or represent a cyclic alkyl group with 3 to 6 carbon atoms , Which is optionally via element, cyano, carboxy, phenyl (which is optionally via element, cyano, ci -C4 -alkyl, Ci -C4 _ from the substituted alkyl group, Ci -C4 _ alkoxy or Ci- This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297mm) (please read the precautions on the back before filling this page) Order 3〇6S〇5 A7 B7_____ V. Description of invention (9) (please read the back Please pay attention to this page and then fill out this page) 〇4-_Substituted by alkoxy group), (: 1 gas 4-alkyl or 〇1-C4-alkoxy-meryl substituted, or representatives were selectively substituted Phenyl, naphthyl or (optionally fused via benzo> heterocyclic group with 5 or 6 ring members, at least one of which represents oxygen, sulfur or nitrogen and, if appropriate, one or two other ring members Represents nitrogen, and the possible substituents are preferably selected from the following series: The Ministry of Economic Affairs, Central Bureau of Economics and Management, employee consumption cooperation, Duyin oxygen production (to replace two hydrogens ), Halogen, cyano, nitro, amine, m, methane, carboxy, aminomethyl, thioaminomethyl, straight or branched alkyl, alkoxy Group, emulsyl group, emulsylsulfenyl group or emulsylsulfonyl group (which have 1 to 6 carbon atoms, respectively), linear or branched alkenyl or alkenyl group (which has 2 to 6 respectively) Carbon atom), straight-chain or branched ketoalkyl, ketoalkoxy, ketothio, ketosulfinyl or # 代 院 基 Continuous amide numbers, respectively, from 1 to 6 carbon atoms and 1 to 13 are the same or different from a prime atom), are straight-chain or branched ketoalkenyl or ketoalkenyloxy (which have 2 to 6 carbon atoms and 1 to 13 are the same or different halogen, respectively) Atom), linear or branched alkylamine group, dialkylamine group, alkylcarbonyl group, alkylmeroxy group, alkyloxycarbonyl group, alkylsulfonyloxy group, plasty imine alkyl group or alkyl group Oxyimidine alkyl groups (which have 1 to 6 carbon atoms in the individual alkyl groups), dialkylene groups or alkanedioxy groups (which have 1 to 6 carbon atoms respectively and which are selected respectively) The same or different Single or multiple substitutions selected from the following substituents: from plain and / or straight-chain or branched papers from Shicaiguanjia (CNS) A4 ^ # · (210X297mm) A7 B7 5. Description of the invention (Ίο) Please read the back matters first and then write down the alkyl group with 1 to 4 carbon atoms and / or straight or branched chain with 1 to 4 carbon atoms and 1 to 9 same or different halogen atoms The radical group), a ring-burning group with 3 to 6 carbon atoms, a heterocyclic group or a heterocyclyl-methyl group with 3 to 7 ring members, respectively (wherein 1 to 3 ring members are the same or different, respectively) Heteroatoms, especially nitrogen, oxygen, and / or sulfur), and phenyl, phenoxymethyl, benzyl, benzyloxy, phenethyl, or phenethoxy groups (which are respectively identical to the phenyl moiety Or different from mono- or poly-substitutions including the following substituents: _ element, cyano group and / or straight bond or branched alkyl group with 1 to 4 carbon atoms and / or straight chain or branched 1 to 4 carbon atoms and 1 to 9 halogenated alkyl groups with the same or different halo atoms and / or linear or branched alkoxy groups with 1 to 4 carbon atoms and / or linear or branched groups with 1 To 4 The sub and】 to 9 are the same or different from the prime atom of the generation of oxygen) 'or X 2 and X 3 together with the gas atoms to form a 3- to 8_ member ring, Printed by the Employees Consumer Cooperative of the Central Ministry of Economic Affairs of the Ministry of Economic Affairs Y1 represents hydrogen, or represents an alkyl group having 1 to 8 carbon atoms, which is optionally selected from the group consisting of A element, cyano group, mesityl group, amine group, C 1 -C 4 -alkyloxy group, C 1 _C4 _ emulsyl group, C 】 -C4-yl sulfinyl group or C 1 -C4 _ burned continuation group (which are optionally substituted by a prime), or represents a cyclic alkyl group with 3 to 6 carbon atoms, which is optionally By _ element, image group, carboxyl group, phenyl group (which is optionally substituted by element, cyano group, Ci-C4-alkyl group, Cl-C4 substituted alkyl group, C1-c4-alkoxy or c1-C 4-substituted by substituted alkoxy groups), C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy-slow groups, or represent optionally substituted phenyl, naphthyl or (select Dijing 12-This paper uses the Chinese National Standard (CNS) A4 (210X297mm)

A7 B7 5. Description of the invention (11) Benzo-fused) heterocyclic group with 5 or 6 ring members, at least one ring member of which represents oxygen, sulfur or nitrogen, and, if appropriate, one or two other ring members Represents nitrogen, and possible substituents are preferably selected from the following series: oxygen (to replace two geminal hydrogen atoms), element, cyano group, nitro group, amine group, _ group, methylol group, carboxyl group, Aminomethyl benzyl group, thioaminomethyl methyl group, linear or branched alkyl group, alkyloxy group, alkylthio group, alkylsulfonyl group or alkylsulfonyl group (which have 1 respectively) To 6 carbon atoms), straight-chain or branched alkenyl or alkenyloxy groups (which have 2 to 6 carbon atoms, respectively), straight-chain or branched monoalkyl, haloalkyloxy, It is a straight-chain or branched group consisting of a substituted thio group, a substituted sulfenyl group, or a substituted hexamethylene group (which has 1 to 6 carbon atoms and 1 to 13 same or different halogen atoms, respectively) Alkenyl group or Alkenyloxy group (which have 2 to 6 carbon atoms and 1 to 13 same or different halogen atoms, respectively), straight-chain or branched alkylamine group, dialkylamine group, alkyl group Group, alkylcarbonyloxy group, alkyloxymeryl group, alkylsulfonyloxy group, iminium alkyl group or alkoxyiminoalkyl group (which have 1 to 6 carbons in each alkyl group part) Atom), dialkylene or alkyldioxy (which have 1 to 6 carbon atoms, respectively) and which are respectively mono- or poly-substituted with the same or different substituents selected from the following groups: Element and / or straight-chain or branched alkyl group having 1 to 4 carbon atoms and / or straight-chain or branched alkyl group having 1 to 4 carbon atoms and 1 to 9 same or different from a substituted alkyl group of a prime atom) , Cycloalkyl groups with 3 to 6 carbon atoms, heterocyclyl groups or heterocyclyl-methyl groups with 3 to 7 ring members, respectively (where -13-this paper scale is applicable to the Chinese National Standard Rate (CNS) 8 4 threat ( 21〇χ297 public and public) Please read the precautions first. A7 B7 printed by the employee consumer cooperative of the Central Bureau of Standards of the Ministry of Economy. V. Description of invention (12) Each of them has 1 to 3 ring members that are the same or different heteroatoms, especially Nitrogen, oxygen, and / or sulfur), and phenyl, phenoxy, benzyl, benzyloxy, phenethyl, or phenethoxy groups (which are selectively The same or different ones are selected from mono- or poly-substitutions including the following substituents: alkyl, cyano, and / or linear or branched alkyl groups with 1 to 4 carbon atoms and / or linear or branched ones With 1 to 4 carbon atoms and 1 to 9 the same or different from the prime atoms of the _ generation burn group and / or straight chain or branched with 1 to 4 carbon atoms of alkoxy and / or straight chain or branched with 1 to 4 carbon atoms and 1 to 9 haloalkoxy groups of the same or different halogen atoms), 1 represents an alkyl group having 1 to 8 carbon atoms, which is optionally selected from the group consisting of prime, cyano, hydroxyl, amine, C 1 -C4 -Alkyloxy, C 1 -C4 -alkylthio, C 1 -alkylsulfinyl, or (: i -c4 -alkylsulfonyl (which are each optionally substituted by element)), or represent Cycloalkyl groups with 3 to 6 carbon atoms, which are optionally via halogen, cyano, carboxyl, phenyl (which is optionally halogen, cyano, Ci -C 4 -alkyl, Ci -C 4 _ _ 代 垸Group, C! -C4-alkyloxy or C 1 _C4-substituted by a substituted alkyloxy), Ci-C4_ alkyl or C1-C4-alkyloxy sulfonyl group 'or representatively selectively substituted Phenyl, stupyloxy, phenylthio, anilino, naphthyl, naphthalene Group, azulenyl group, azulenyl group or (optionally fused via benzo) heterocyclic group, heterocyclic oxy group, heterocyclic thio group and heterocyclic amine group, each having 5 or 6 ring members (of which at least One represents oxygen, sulfur, or nitrogen, and, if appropriate, one or two other ring members represent nitrogen), possible substituents are preferably selected from the following series: -14-This paper size applies to the Chinese National Standard ( CNS) A4 specification (210X297mm) (please read the note on the back Ϋ item 4 4 to write this page first) Ordered by the Ministry of Economic Affairs Central Bureau of Samples and Printing Cooperative Printed by the Ministry of Economic Affairs Central Standards Bureau Employee Consumer Cooperative Printed A7 B7 V. Description of the invention (13) Oxygen (to replace two geminal hydrogen atoms), element, cyano group, nitro group, amine group, drag group, methylacetate group, carboxyl group, aminomethylacetate group, thioamine group Onychomycin, linear or branched alkyl, alkoxy, alkylthio, alkylsulfinyl or alkylsulfonyl (which have 1 to 6 carbon atoms, respectively), linear Or branched alkenyl or alkenyloxy groups (which have 2 to 6 carbon atoms, respectively), straight-chain or branched substituents, substituents Group, alkoxyalkylthio group, alkoxyalkylsulfinyl group or i-generation compound (which has 1 to 6 carbon atoms and 1 to 13 same or different _ element atoms, respectively), which are straight-chain or Branched alkenyl groups or alkenyloxy groups (which have 2 to 6 carbon atoms and 1 to 13 same or different halogen atoms, respectively), linear or branched alkylamine groups, dialkylamine groups, An alkylcarbonyl group, an alkylcarbonyloxy group, an alkyloxycarbonyl group, an alkylsulfonyloxy group, an iminoalkyl group, or an alkoxyiminoalkyl group (which have 1 to 6 in each alkyl part, respectively) Carbon atoms), dialkylene or alkyldioxy groups (which have 1 to 6 carbon atoms, respectively) and are optionally substituted by the same or different substituents selected from the following groups including mono- or poly-substituted: (Straight-chain or branched alkyl group having 1 to 4 carbon atoms and / or straight-chain or branched halogen group having 1 to 4 carbon atoms and 1 to 9 same or different halogen atoms) , A cycloalkyl group having 3 to 6 carbon atoms, a heterocyclic group or a heterocyclyl-methyl group having 3 to 7 ring members, respectively (wherein 1 to 3 ring members are the same or different heteroatoms, especially nitrogen ,oxygen And / or sulfur), and phenyl, phenoxy, benzyl, benzyloxy, phenethyl or phenethoxy groups (which are selected from the phenyl moiety through the same or different, and are selected from the following substituents The order is replaced or taken more -15-This paper scale is applicable to the Chinese National Standard (CNS) Α4 specification (210Χ297 public and public) (please read the notes on the back and write this page),? Τ A7 ________B7 V. Invention Description (14) Generation: the alkyl group with 1 to 4 carbon atoms and / or the straight chain or branched with 1 to 4 carbon atoms and 1 to 9 are the same or Different _ prime atoms of the substituted alkyl group and / or linear or branched alkoxy group with 1 to 4 carbon atoms and / or linear or branched group with 1 to 4 carbon atoms and 1 to 9 are the same or different (Substituted from a prime atom) · Saturated or unsaturated hydrocarbon chains (such as alkyl, alkanediyl, homing or dialkyl) as defined above and those connected to heteroatoms (such as alkyloxy, alkyl Thio or alkylamine groups) are linear or branched, respectively. Halogen generally represents fluorine, gas, bromine or iodine, preferably fluorine, gas or bromine, especially fluorine or gas. In particular, the present invention relates to compounds of formula (I) in which each symbol has the following definition:

Ar represents ortho-, meta- or para-phenylene, which is optionally substituted, or represents pyrandiyl, beta-phenylene diyl, pyrridinediyl, oxadiyl, triazolyl , Oxazolyl diyl, isoxazolyl diyl, thiazolyl diyl, isothiazolyl diyl, oxadiazolyl diyl, thiadiazole diyl, pyridine diyl, mouth bite monoyl, spray spider diyl, she peak Diyl, 1,3,4-trimodal diyl or 1,2,3-tri read diyl, possible substituents are specifically selected from the following series: fluorine, gas, cyano, methyl, ethyl, Trifluoromethyl group, methoxy group, ethoxy group, methylthio group, methyl sulfide cross-chain group or methyl conjugated group, E represents one of the following groups: -16 * This paper size ϋ Cai Guo ® Home (CNS) A4 ^ (2 丨 Gx297 public and private) Fill out this page) Printed 3〇6S35 A7 B7 printed by Beigong Consumer Cooperative of the Central Bureau of Economics of the Ministry of Economy V. Description of the invention (15)

Where Y represents oxygen, sulfur, methylene (CH2) or alkylimino (NR), R represents methyl, ethyl, n- or iso-propyl, or n-, iso- or second-butane base,

Ri represents hydrogen, fluorine, gas, bromine, cyano, or represents methyl, ethyl, propyl, methoxy, ethoxy, methylthio, ethylthio, methylamino, ethylamino or dimethyl Amino group, which is optionally substituted by fluorine, gas, cyano, methoxy or ethoxy, R2 represents hydrogen, amine or cyano, or represents methyl, ethyl, methoxy, ethoxy , Methylamino, ethylamino or dimethylamino, which are optionally replaced by fluorine, gas, cyano, methoxy or ethoxy, respectively, and are printed by the Beigong Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs (please Read the notes on the back first ^: fill in this page) R3 represents hydrogen, cyano, or methyl, ethyl, n- or iso-propyl or n-, iso- or second-butyl, which are respectively selected Substituted by fluorine, cyano, methoxy or ethoxy, or represents allyl or propyl, or cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cyclopropylmethyl, Cyclobutylmethyl, cyclopentylmethyl or cyclohexylmethyl, which are selected from fluorine, gas, cyano, carboxyl, methyl, ethyl, n- or iso-propyl, methoxy-meryl or B Substituted by the carbonyl group, the paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm). The A7 B7 is printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economy. V. Description of invention (16) G stands for oxygen, or stands for methylene Group, dimethylene (ethane-1,2-diyl), ethylene-1,2-diyl or ethane-1,2-diyl, which are selectively selected from gas, gas, wiki, methyl , Ethyl, n- or iso-propyl, trifluoromethyl, cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl, or represents one of the following groups: -Q-CQ-, -CQ -Q-, .-CH2-Q-, -Q-CH2-, -CQ-Q-CH2- -CH2-Q-CQ-, -Q-CQ-CH2-, -Q-CQ-Q-CH2-, -Ν = Ν-, -S (0) n- -CH2-S (0) n-, -CQ-, -S 《0) n-CH2-, -C (R4) = N-0- -C ( R4) = N-0-CH2-, -N (R5)-, -CQ-N (R5)-, -N (R5) -CQ- -Q-CQ-N (R5)-, -N »C ( R4) -Q-CH2, -CH2-0-N = C (R4)--N (RS) -CQ-Q-, -CQ-N (RS) -CQ-Q- or -N (R5 Bu CQ- Q-CH2- where n represents 0, 1 or 2, Q represents oxygen or sulfur, R4 represents hydrogen or cyano, or represents methyl, ethyl, n- or iso-propyl, n-, iso- or second -Butyl, methoxy, ethoxy, propoxy, butoxy, methylthio, Sulfur, propylthio, butylthio, methylamino, ethylamino, propylamino, dimethylamino or diethylamino, which are selected from fluorine, gas, cyano, methoxy or ethoxy Substituted by a group, or represents cyclopropyl, cyclobutyl, cyclopentyl, or cyclohexyl, which is optionally selected from fluorine, gas, cyano, carboxy, methyl, ethyl, n- or iso-propyl, methyl Oxycarbonyl or ethoxy-carbonyl, and R5 represents hydrogen, m or cyano, or represents methyl, ethyl, n- or iso-propyl or n-, iso-, second- or Three_butyl, the paper size is in accordance with Chinese National Standard (CNS) Α4 specification (210X: 297 mm) (please read the notes on the back # fill in this page). 丄

, 1T A7 B7

V. Description of the invention (17 / It is optionally substituted by fluorine or gas, or represents cyclopropyl, which is optionally substituted by gas ethyl, n- or iso-propyl, X represents -0X 1, -SX 1 , -SOX cyano, methoxy or 6-oxycyclobutyl, cyclopentyl or cyclohexyl gas, cyano, carboxyl, methyl, methoxycarboxy or hexoxycarbonyl, -S〇2 XI or -Νχ2 X3, please read the first printed by the Beigong Consumer Cooperative of the Central Bureau of Economics of the Ministry of Economic Affairs, where χι, Χ2 and X3 independently represent hydrogen, or represent methyl, ethyl, n- or hetero-two bases or n_, Iso-, first- or second-butyl, which is optionally selected from fluorine, gas, bromine, cyano, benzyl, amine, methoxy, ethoxy, methylthio, ethylthio, methyl Sulfenyl, ethylsulfinyl, methylsulfonyl or ethylsulfonyl (which are optionally substituted by fluorine and / or gas, respectively), or represent cyclopropyl, cyclobutyl, Cyclopentyl or cyclohexyl, which is optionally fluorine, gas, bromine, cyano, carboxy, phenyl (which is optionally fluorine, gas, bromine, cyano, methyl, ethyl, n- or iso- Propyl, n- Iso-, second- or third-butyl, trifluoromethyl, methyl radon, ethoxy, n- or iso-propoxy, difluoromethoxy or trifluoromethoxy), Methyl, ethyl, n- or iso-propyl, methoxy-succinyl or ethoxy-acyl substituted, or represents a substituted phenyl, azulenyl, thiopyranyl, tetra Hydrogen time furanyl, benzo weight furanyl, tetrahydroarpyranyl, pyrenyl, benzo II thiophene, time uryl, dihydropyrrolyl, tetrahydroportitrolyl, benzomkrolyl , Benzodihydropyrrolyl, oxazole-19-fill in this page to order A7 B7 with China National Standard (CNS) A4 (210X297mm) 5. Description of the invention (18) base, benzoxazole Group, isoxazolyl, D sezolyl, benzthiazolyl, isothiazolyl, imidazolyl, benzimidazolyl, oxadiazolyl, thiadiazolyl, arimidinyl, pyrimidinyl, pyridazyl, cnt oxalyl, 1,2,3-trioxalyl, 1,2,4-trioxalyl or 1, 3,5-trioxalyl, possible substituents are preferably selected from the following series of oxygen (use To replace two hydrogen atoms), fluorine, gas, bromine, cyano, nitro, Group, m group, formyl group, carboxyl group, amino formyl group, thioamino formyl group, methyl group, ethyl group, n- or iso-propyl group, n-, iso-, second- or first Tri-butyl, methoxy, ethoxy, n- or iso-propoxy, methylthio, ethylthio, n- or iso-propylthio, methyl sub-item, ethyl sub-item Alkyl, methyl ethyl or ethyl ethyl alcohol, three gas methyl, two gas methyl, three gas methoxy, two gas methylthio, three gas methylthio, trifluoromethylsulfinyl Acetyl or trifluoromethylsulfonyl, methylamino, ethylamino, n- or iso-propylamino, dimethylamino, diethylamino, ethylacetyl, propionyl, ethyloxy, Methoxycarbonyl, ethoxycarbonyl, methanesulfonyloxy, ethylsulfonyloxy, m-iminomethyl, m-iminoethyl, methoxyiminomethyl, ethoxyimino Methyl, methoxyiminoethyl or ethoxyiminoethyl •, or trimethylidene (propane-1,3-diyl), methylenedioxy or ethylenedioxy, respectively Mono- or poly-substituted by the same or different substituents selected from , Ethyl and n 'or iso-propyl; or cyclopropyl, cyclobutyl, -20 The paper size is applicable to China National Standards (CNS) Μ specifications (210Χ297 mm) Please read the back note to set the Central Ministry of Economic Affairs A7 B7 S06S65 printed by the Staff Consumer Cooperative of the Bureau of Standards V. Description of the invention (19) Cyclopentyl or cyclohexyl, and phenyl, phenoxy, benzyl or benzyloxy, which are selectively the same in the phenyl part Or different from mono- or poly-substitutions including the following substituents: fluorine, gas, bromine, cyano, methyl, ethyl, n- or iso-propyl, n-, iso-, second- or Tri-butyl, trifluoromethyl, methoxy, ethoxy, n- or iso-propoxy, difluoromethoxy or trifluoromethoxy, or X 2 and X 3 are formed together with the nitrogen atom A 5-, 6-, or 7-membered hard ring, which optionally contains one or two additional heteroatoms, such as nitrogen, oxygen, and / or sulfur, γ1 represents hydrogen, or represents methyl, ethyl, n-or Iso-propyl or n-, iso-, second- or third-butyl, which are selected from fluorine, gas, bromine, cyano, m-, amine, methoxy, ethoxy, methyl Sulfur-based, Ethylthio, methylsulfinyl, ethylsulfinyl, methylsulfinyl or ethylsulfinyl (which are optionally substituted by fluorine and / or gas, respectively), or represent cyclopropyl Group, cyclobutyl, cyclopentyl, or cyclohexyl, which are optionally fluorine, gas, bromine, cyano, carboxyl, phenyl (which is optionally fluorine, gas, bromine, cyano, methyl, ethyl , N- or iso-propyl, n-, iso-, second- or third-butyl, trifluoromethyl, methoxy, ethoxy, n- or iso-propoxy, difluoromethane Substituted by oxy or trifluoromethoxy>, methyl, ethyl, n- or iso-propyl, methoxy-carbonyl or ethoxy-meryl, or represents substituted Phenyl, steamed, 0-flavored, tetrakidyl, benzopyranyl, tetrakispyranyl, II-cephenyl, benzo-II-sephenyl, sherrolyl, dihydro 21-Ben The paper standard is applicable to the Zhongguan Jiadi Standard (CNS) A4 specification (2 丨 Gx297 public envy). Please read the precautions first. I will print the A7 printed by the Beigong Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs.

The invention description printed by the Beigong Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs (200 bilokyl, tetrahydropyrrolidyl, benzopyrrolidine, benzodihydrolbiloxiryl, oxazolyl, benzo Zazolyl, isopyridyl, beta-sebolyl, benzyl semenyl, isopyridyl, imidazolyl, benzimidyl, chewed bite, oxadiazolyl, mt pyridine Group, pyrimidinyl group, pyridyl group, pyrido group,〗, 2,3-dioxyl group, 1,2,4-trisyl group or〗, 3,5_trisyl group, possible substituents are preferably It is selected from the following series: Oxygen (to replace two geminal atoms), fluorine, gas, bromine, tritium, nitro, amine, m, methane, carboxy, amine methyl, sulfur Aminoamino flat chain, methyl, ethyl, n- or iso-propyl, n-, iso-, second- or second-butyl, methoxy, ethoxy, n- or iso- Propoxy, methylthio, ethylthio, n- or iso-propylthio, methylsulfinyl, ethylsulfinyl, methylsulfonyl or ethylsulfinyl, trifluoromethane Group, difluoromethoxy group, trifluoromethyl gas group, difluoromethylthio group, trifluoromethylthio group, trifluoro Sulfenyl or trifluoromethylsulfonyl, methylamino, ethylamino, n- or iso-propylamino, dimethylamino, diethylamino, ethyl chain, propanoyl, ethyl chain Oxy, methoxy, ethoxycarbonyl, ethoxycarbonyl, methanesulfonyloxy, ethylsulfonyloxy, imidomethyl, miminoethyl, methoxyiminomethyl, Ethoxyiminomethyl, methoxyiminoethyl or ethoxyiminoethyl; or trimethylene (propane-1, 3-diyl), methylenedioxy or ethylenedioxy, which It is mono- or poly-substituted with the same or different substituents selected from the group consisting of fluorine, gas, methyl, ethyl and n- or iso-propyl; or cyclopropyl, cyclobutyl, cyclo Amyl or cyclohexyl, as well as phenyl, phenoxy, benzyl or benzyl radon, which are selected in the phenyl part -22 This paper scale is applicable to the Chinese National Standard (CNS) A4 specifications (210X297) Please read the note page first to order A7. V. Description of the invention (21 / Single or multiple substitutions selected from the same or different substituents including the following: fluorine, gas, bromine, cyano, methyl, ethyl , -Or iso-biyl, n-, iso-, second- or third-butyl, trifluoromethyl, methoxy, ethoxy, n- or iso-propoxy, difluoromethoxy Or trifluoromethoxy, or printed by the Beigong Consumer Cooperative of the Central Bureau of Economic Affairs of the Ministry of Economic Affairs (please read the notes on the back to write this page). Order 1 represents methyl, ethyl, n- or iso-propyl or n- -, Iso-, second_ or tertiary-butyl, which are optionally selected from fluorine, gas, bromine, cyano, hydroxy, amine, methoxy, ethoxy, methylthio, ethylthio , Methylphosphoranylidene, ethylsulfinylsulfonyl, methylsulfonyl or hexylsulfonyl (which are optionally substituted by fluorine and / or gas, respectively), or represent propyl, croton Alkyl, 1-methyl-allyl, propyl-deficient or p-methyl-propyl, which are optionally substituted by fluorine, gas or bromine 'or represent cyclopropyl, cyclobutyl, cyclopentyl or cyclo Hexyl, which is selected from fluorine, gas, bromine, nitrogen, carboxy, and phenyl (which is selected from gas, gas, bromine, cyano, methyl, ethyl, n- or iso-biyl, n -, Iso-, second- or third-butyl, trifluoro Methyl, methoxy, ethoxy, n- or iso-propoxy, difluoromethoxy or trifluoromethoxy substituted), methyl, ethyl, n- or iso-propyl, methyl Substituted by oxymeryl or ethoxy-carbonyl, or represents optionally substituted phenyl, naphthyl, cranulyl, tetrahydrocranyl, benzofuranyl, tetrahydroportitranyl, respectively , Thienyl, benzod thiophene, pyrrolyl, dihydro-octyl, tetrahydrooitrolyl, benzopyrrolyl, benzodihydropyrrolyl, benzyl, benzoxazole , Isopurazolyl, B Sezolyl, Benzothiazolyl, Isothiol, Isothyronyl, Benzimidyl Bite, Drinking Bite, D Plug II 23-This paper is again suitable for Chinese countries Standard (CNS) A4 specification (210X297 mm) A7 _____B7_ V. Description of invention (22) Zazolyl, arimidinyl, pyrimidinyl, pyridabenyl, oxalyl, 1, 2,3-trisyl, 1 , 2,4-triazinyl or 1, 3, 5-trisyl, phenoxy, azulenyloxy, crananoxy, tetrahydrocranyloxy, benzofuranoxy, tetrahydropyranyloxy Base, II-phenoxy, benzo-II-phenoxy, imidoxy, dihydrota Slightly oxy, tetrahydro-OJt azole oxy, benzoxyl oxy, benzodihydroimidrol oxy, oxazolyl oxy, benzopurazolyl oxy, isoxazolyl oxy, D thiazolyl oxy , Benzo-D-Sezozoyloxy, isothiazolyloxy, imidazolyloxy, benzimidyloxy, oxadiazolyloxy, B-pyridyloxy, orthopyridyloxy, pyrimidinyloxy, pyridazoyloxy Oxygen, valoryl radon, 1,2,3-trisyloxy, 1,2,4-trisyloxy or 1, 3,5-trisoxyl, phenylthio, teathio, Alpha-flavored thio, tetrahydro-g-flavored, benzofuran, thiosulfanyl, thiophene thio, thiophene thio, thiophene thio, thiosulfate, dihydro Djfc Thio, tetrahydroarrazine, benzopyrrole thio, benzodihydropyridine thio, oxazole thio, benzo oxazole thio, isoxazole thio, thiazole thio, benzene Thiothithio, isothiazolylthio, imidazolylthio, benzimidazolylthio, oxadiazolylthio, oxadiazolylthio, pyridylthio, pyrimidinethio, pyridathio, sulfhydryl , 1,2,3-triazinethio, 1,2,4-tristhio, or 1,3,5-tristhio, anilino, naphthylamino Crananosamino, tetrahydrofuranamino, benzofuranamino, tetrahydroaitranamino, thienylamino, benzothiophenamino, pyrrolyl, dihydropyrrolidinyl, tetra Hydrogen tntpyrrolyl, benzopyrrolyl, benzodihydrocntpyrrolyl, oxazolyl, benzoxazolyl, isoxazolyl, thiazolyl, benzo II thiazolyl , Isothiazolylamino, imidazolylamino, benzimidazolylamino, oxadiazole 24-This paper uses the Chinese National Standard (CNS > Μ specifications (2 丨 0X297 public envy). Please read the back

I Printed A7 ___B7 amine group, quaternary amine group, acetaminophen group, pyrimidine amine group, pyridamin amine group, oral oxamine amine group, 込 2,3_Sanso Amino group, I 2,4_trioxaminyl group or ^ 3,5-triazinylamino group, possible substituents are preferably selected from the following series: gas (for the replacement of two hydrogen atoms), Fluorine, gas, bromine, cyano, nitro, amine, benzyl, methanoyl, carboxy, carbamoyl, thioamino, benzyl, methyl, ethyl, n- or iso-propyl Basic, positive-, printed by the Central Bureau of Economic Affairs of the Ministry of Economic Affairs, Zhengong Consumer Cooperative, iso-, second- or third-butyl, methoxy, ethyl radon, normal- or hetero-two gas, methylthio , Ethylthio or isopropylthio, methyl pyridyl, methyl sub-entry group, methyl chain or ethyl group, tri-methyl, difluoromethoxy, trifluoro Methoxy group, difluoromethylthio group, trifluoromethyl group, trifluoromethyl sub-group or trifluoromethyl group, methylamino group, ethylamino group, n- or iso-propylamino group, di Methylamino, di & amine, 6-octyl, propionyl, ethoxy, Methoxy group, & amino group Momo, methyl continued chain oxy group, ethyl continued chain oxyimino group, amine, sulfonamide group, methoxy imino group methyl group, ethyl group Oxyimine & methyl curtain, methoxyaminoethyl or hexyloxyiminoethyl; or trimethylene (carbo-1,3-diyl), methylenedioxy or ethylenedioxy, They are mono- or poly-substituted by the same or different substituents selected from the group consisting of fluorine, gas, methyl, ethyl and n- or iso-propyl; or cyclopropyl, cyclo Butyl, cyclopentyl or cyclohexyl, as well as phenyl, phenoxy, benzyl or benzyloxy, which are respectively mono-substituted or substituted on the phenyl moiety by the same or different substituents selected from Multiple substitutions: gas, gas, bromine, cyano, methyl, ethyl, n- or iso-propane-25 This paper scale uses the Chinese National Standard (CNS) Α4 specification (2 丨 0 > < 297mm) A7 B7 5. Description of the invention (24) Radical, n-, iso-, second- or third-butyl, trifluoromethyl, methoxy, ethoxy, n- or iso-propoxy, digas Methoxy or three gas methoxy · Especially good According to the present invention is a compound wherein the symbols have the following definitions compound of formula (I):

Ar stands for ortho-phenylphenyl, ait bit-2,3-diyl or II phenphen-2,3-diyl, and E stands for one of the following groups (please read the notes on the back ^ from writing this page ).

, 1T

R1 and R 2 respectively represent methoxy, G represents oxygen, methyl or one of the following groups -CH2-0-, -0-CH2-, -S (0) n-, -CH2-S (0) n-, -S (0) n-CH2-, -C (R4) «Ν-0-, -0-N = C (R4)-, -C (R4) _N-0-CH2-, -N ( R5) -or-CH2-0-N = C (R4)-, printed by the Employee Consumer Cooperative of the Central Prototype Bureau of the Ministry of Economic Affairs where n stands for 0, 1 or 2, R4 stands for hydrogen, methyl or ethyl, and R5 stands for hydrogen , Methyl or ethyl, X represents -0X1, -SXi, -SOXi '-S02X1 or -NX2X3, where χ 1, X2, and X3 independently represent hydrogen, or represent methyl, ethyl, and paper standards apply to China's national standards (CNS) Α4 specification (210X297mm) Cooperation with Beigong ift of the Central Bureau of Economics of the Ministry of Economic Affairs. Co., Ltd. A7 B7, invention Zhuming (25) base, n- or iso-propyl or n-, iso-, Di- or tertiary-Dingmu, which are optionally replaced by fluorine, gas, cyano, wiki, amine, methoxy, methylthio (which are replaced by fluorine and / or gas, respectively) , Or represents cyclopropyl, cyclobutyl, cyclopentyl, or cyclohexyl, which are selectively fluorine, gas, bromine, cyano, carboxyl, benzene (which is selectively fluorine, gas, methyl, tri Substituted by fluoromethyl or trifluoromethoxy), methyl, ethyl, n- or iso-propyl, methymeryl or ethoxycarbonyl ”or represent a substituted phenyl, Pyridyl, pyrimidinyl, pyridyl, pyrido, 1,2,3-trisyl, 1,2,4-trisyl or 1,3,5-trisyl, possible substituents are preferred The ground is selected from the following series: fluorine, gas, bromine, cyano, methyl, ethyl, n- or iso-propyl, n-, iso-, second- or third-butyl, methoxy , Ethoxy, n- or iso-propyl cyano, methyl bowl, ethyl aryl, n 'or iso-propyl thio, methyl sulfenyl, ethyl sulfenyl, methyl sulfenyl Or ethylsulfonylsulfonyl, trifluoromethyl, difluoromethanyl, trifluoromethoxy, difluoromethylthio, trifluoromethylthio, trifluoromethylsulfinyl, or trifluoromethyl Sulfoepoxy, methoxycarbonyl, ethoxybranched, foxyimidylmethyl, ethoxyimidylmethyl, methoxybenzylethyl or ethoxyimidylethyl, or methylenedi Gas-based or ethylenedioxy, which are selected by the same or different options (please read the notes on the back first Matters to write this page again} Order 'Finished!

-27 _______B7 V. Description of the invention (26) Single or multiple substitutions from the following substituents: gas, gas, methyl or ethyl, or phenyl, phenoxy, benzyl or benzyloxy, respectively Optionally, the phenyl moiety is mono- or poly-substituted with the same or different substituents selected from the group consisting of: gas, gas, bromine, cyano, methyl, ethyl, n- or iso-biyl, n- _, Iso-, second- or third-butyl, trifluoromethyl, methoxy, ethoxy, n- or iso-propoxy, difluoromethoxy or trifluoromethoxy, or X2 and X3 together form a pyridine, imidazole or triazole ring, which is optionally substituted as described above, Y1 represents hydrogen, or represents methyl, ethyl, n- or iso-propyl or n-, iso -, Second- or third-butyl, which are optionally substituted by fluorine, fluorine, cyano, m-, amine, methoxy, methylthio (which are optionally substituted by fluorine and / or gas, respectively) ) Is substituted, or represents cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl, which are selectively fluorine, gas, bromine, cyano, carboxyl, phenyl (which is selectively fluorine, gas, methyl ,three Substituted with methyl or trifluoromethoxy), methyl, ethyl, n - or iso - propyl, methoxycarbonyl or ethoxycarbonyl substituent. Printed or representatively selected by the Central Sample Bureau of the Ministry of Economic Affairs, Beigong Consumer Cooperatives for substituted phenyl, pyridyl, pyrimidinyl, beehyl, chrysantyl, 1,2,3-trisyl, 1, 2,4-Tri-amyl group or 1, 3, 5-trisyl group, possible substituents are preferably selected from the following series: The paper size is applicable to China National Standard (CNS) A4 specification (210X297 public) A7 B7 ----------------------- V. Description of the invention (27) Fluorine, gas, stream, atmosphere, methyl, dagger, n-or Iso-propyl, jade-, iso-, first- or second-butyl, methoxy, ethoxy, or iso-carbooxy, methylthio, ethylthio, n- or iso-propyl Sulfur, methylsulfonyl, ethylsulfonyl, methylsulfonyl or ethylsulfonyl, trifluoromethyl, difluoromethoxy, trifluoromethoxy, difluoromethylsulfide Group, trifluoromethylthio, trifluoromethylsulfinyl or trifluoromethylsulfinyl, foxy oxy, ethoxycarbonyl, methoxyiminomethyl, ethoxymethyl Group, methoxyiminoethyl or ethoxyiminoethyl, or methoxydioxy or ethanedioxy (which are respectively selected Mono- or poly-substituted by the same or different substituents selected from fluorine, gas, methyl or ethyl), or phenyl, phenoxy, octyl or huaoxy (which are selected from benzene and benzene respectively) The radicals are selected from the same or different groups including fluorine, gas, bromine, cyano, methyl, ethyl, n- or iso-propyl, n-, iso-, second, or third-butyl , Trifluoromethyl, methoxy, ethoxy, n- or iso-propoxy, difluoromethoxy or trifluoromethoxy substituents are mono- or poly-substituted>, Central Bureau of Standards, Ministry of Economic Affairs The Z printed by the employee consumer cooperative stands for the optionally substituted phenyl, arimidinyl, pyrimidinyl, dasalyl, talipine, 1,2,3_diitchyl, 1,2,4_trisophonic groups. Or 1, 3,5-trisyl, phenoxy, pyridinyloxy, pyrimidinyloxy, pyridaxyloxy, pyridoxyloxy, 1,2,3-trisyloxy, 1,2, 4 -Trisyloxy or 1,3,5-trisyloxy, phenylthio, pyridinethio, pyrimidinethio, pyridazinylthio, arsenylthio, 1, 2, 3-triazinethio , 1, 2, 4-trisylthio or 1,3,5-trisylthio, aniline, oximidine, Pyridylamino, pyridamidyl, pyridolamido, 1, 2, 3- -29-This paper scale is applicable to China National Standard (CNS) A4 specification (210X297mm) B7 V. Invention description (28) III Aziramine group, 1,2,4-trisylamino group. Or 1,3,5-trisylamino group's possible substituents are preferably selected from the following series: fluorine, gas, bromine, cyano, Methyl, ethyl, n- or iso-propyl, n-, iso-, second- or third-butyl, methoxy, ethoxy, n- or iso-propoxy, methyl broken group , Ethyl broken group, n- or iso-propyl broken group, methyl sulfinyl succinyl group, ethyl sulfinyl parthenyl group, methyl sulfonyl or ethyl sulfonyl group, trifluoromethyl, difluoromethoxy , Trifluoromethoxy, difluoromethylthio, trifluoromethylthio, trifluoromethylsulfinyl or trifluoromethylsulfinyl, methoxysulfonyl, ethoxycarbonyl, methoxy Aminomethyl, ethoxyiminomethyl, methoxyiminoethyl or ethoxyiminoethyl, or methoxydioxy or ethanedioxy (which are respectively selected by the same or different Mono- or poly-substituted by substituents including fluorine, gas, methyl or ethyl), or Group, phenoxy group, benzyl group or benzyloxy group (which are respectively selected from the same or different from the phenyl moiety including fluorine, gas, brook, gas group, methyl, ethyl, n- or iso- Propyl, n-, iso-, second- or third-butyl, trifluoromethyl, methoxy, ethoxy, n- or iso-propoxy, difluoromethoxy or trifluoromethyl Oxy substituents are mono- or multi-substituted). The definitions of the aforementioned bases (general or better) printed by the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs are applicable to the final product of formula (I) and similarly the starting materials or intermediates required in the preparation thereof . The definitions of these radicals can be combined with each other as desired, that is, it is possible to combine with each other within the scope of the aforementioned preferred compounds. If, for example, [2- (2-methylphenoxymethyl) phenyl] -2-methoxyphosphonothiothioacetic acid methyl ester and 0-methyl-dimensional gas are used as starting -30- National Standards (CNS) (210X297mm) 3

OCH, alkali

A7 B7 V. Description of the invention (¾) The starting material, the reaction process according to the method (a) of the present invention can be expressed by the following formula:

h2n—och3x hci If, for example, N-methyl- {2- [Bu (3-trifluoromethylphenyl> -ethyleneaminooxymethyl] -phenyl} -2-methoxy If the imino-thioacetamide is used as the starting material, methyl iodide is used as the emulsifying agent and 0-methyl m ammonium vapor is used as another starting material, the reaction process according to the method (b) of the present invention can The following expression: Please read the notes on the back V fill this page CF,

CH ^ I test ch3on = c, c-nhch3 cf3 CHjON = C, C = NCH, I 3 SCH, * h2n-och, x hci a CFt CHjON = C% C-NHCH, II ^ OCH, Central Bureau of Standards, Ministry of Economic Affairs Printed by employee consumer cooperatives, for example, using N-methoxy- [2- (2-methylphenoxymethyl) phenyl] -2-methoxyiminothioacetamide as the starting material , Using methyl iodide as the alkylating agent and dimethylamine as another starting material, the reaction process according to the method (c) of the present invention can be expressed by the following formula: -31-This paper scale is applicable to the Chinese National Standard (CNS) A4 Specification (210 > < 297mm) A7 B7 5. Description of the invention (30)

The Ministry of Economic Affairs, Central Bureau of Standards, Beigong Consumer Cooperative Association (K) provides the general definition of the thiosulfonyl derivative as the starting material required to carry out the method (a) according to the present invention. In formula (Π), Ar, E, G, X1, and Z are preferably, or in particular, preferably mentioned in the description of the compounds of formula (I), or particularly preferred , Definition 〇The formula (I) thiobenzyl derivatives are known (details, for example, EP-A-432 503) or can be prepared according to the standard methods described in the literature, for example, the corresponding formula (VB) Ketone Derivatives-32-This paper is suitable for use in Jiajia County (CNS): 4 threats (21 () > < 297 public envy) 5. Description of the invention (magic), GW〇 (s) x1

II 0 (VII) where

Ar, E, G, XI and Z have the aforementioned definitions, and sulfide #! 'Such as P4 Si〇 or Lu Yisheng test # | (Lawesson reagent) 〔2, 4-bis (4-methoxyphenyl) -1, 3, 2, 4-dithiadiane (phosphetane-2,4-dithione)], at a temperature between 80 and 200.00, if appropriate for dilution, such as xylene or toluene , In the reaction (detailed preparation examples). The keto derivatives of formula (VB) are known or can be prepared according to known methods (details, for example, ΕΡ-Α 253 213, ΕΡ-Α 254 426, ΕΡ-Α 299 694, ΕΡ-Α 432 503, ΕΡ- Α 460 575). The formula (1Π) provides a general definition of the chicken amine derivative used to carry out the method (a) according to the invention and is required as a starting material. In the formula (leg), γ1 is preferably, or in particular, having the definition mentioned above in the description of the compound of formula (I) as preferably or particularly good in the description of the substituent group. The amine derivative of formula (β) m and its acid addition weight (such as its hydrogen acid and acetate) are compounds known in general organic chemistry or can be prepared according to the standard methods described in the literature. Formula (IV) provides The general definition of the amide derivatives used as starting materials for carrying out the method (b) according to the invention. In formula (IV), Ar, E, G, X3 and Z are preferably, or in particular, have The above mentioned definitions of these substituents in the description of the compound of formula (j) are better, or particularly good, and defined. A7 B7 5. Description of the invention (32) The amine derivatives of formula (IV) are not known in the literature. However, they can be prepared according to the standard methods described in the literature, for example, the corresponding keto derivatives of the formula τ .G., Ar -E ^ NHX, 〆II ο 3 (VIII) Central Ministry of Economic Affairs Printed by the Industrial and Consumer Cooperatives, where Ar, E, G, X3, and Z have the aforementioned definitions, and vulcanizing agents, such as P 4 Si〇 or Louis Reagent [2, 4-bis (4-methoxyphenyl) -1, 3,2,4-Dithiodiphosphorane-2,4-dithione], at a temperature between 80 and 20 〇t, if suitable for diluent (such as xylene or methyl Benzene), the reaction (also detailed examples of preparation). Keto derivatives of formula (VI) are known or can be prepared by known methods (detailed, for example, W0-A 92/13 830), for example, the formula (VD) Ketone derivatives are reacted with appropriate amines. Suitable alkylating agents for carrying out the methods (b) and (c) of the present invention are conventional reagents, for example: alkyl based compounds (especially methyl gas, methyl alcohol Alkyl bromide and methyl iodide) and dialkyl sulfate (especially dimethyl sulfate). The alkylating agent is a compound known in general organic chemistry. Formula (V) is provided for carrying out the method (c) according to the invention The general definition of the acetamide derivative required as a starting material. In formula (V), Ar, E, G, γι, and Z are preferably, or in particular, have the preceding description in the compound of formula (I) These substituents are better mentioned in the industry, or in particular to the definition. Part (V) Parthenamine derivatives are not yet known in the literature. However, they can be applied to the Chinese National Standard (CNS according to -34-Thai paper X degree) ) A4 specification (210X297mm) (Please read the notes on the back to write this page)

, 1T A7 B7 Fifth, the description of the invention (33) The standard method described in the literature, for example, the corresponding ketone derivatives of formula (IX) The Ministry of Economic Affairs Central Standards Bureau employee consumer cooperatives printed Ar, E, G, Y1 And Z have the aforementioned definitions, and a vulcanizing agent, such as P 4 S10 or Lewis reagent [2,4-bis (4-methoxyphenyl) _1,3,2,4-dithiodilinol-2, 4-Dithione], at a temperature between 80 and 200 eC, if appropriate in a diluent (such as xylene or toluene), the reaction. Keto derivatives of formula (IX) are not known in the literature. However, they can be prepared according to standard methods described in the literature. For example, the methyl esters of formula (VB) (XI = CH3) and formula (1Π) are reacted via an amine derivative according to method (a). Suitable diluents for carrying out the methods (a) to (c) according to the invention are inert organic solvents. The following compounds are preferably used: aliphatic, cycloaliphatic, or aromatic hydrocarbons, such as volatile oils, benzene, toluene, xylene, gas benzene, petroleum ether, hexane, cyclohexane, digas, methyl, etc. Gas imitation, four-gasification carbon; ethers, such as diethyl ether, dioxane, tetrahydrofuran, ethylene glycol dimethyl ether or ethylene glycol diethyl ether; arsine, such as ethyl arsine or propane arsine; amides , Such as dimethylformamide, dimethylacetamide, N-methylformylanilide, N-methyloit ketone or hexamethyltrisamine phosphate; esters, such as ethyl acetate; Sub-types, such as dimethoate; alcohols, such as formazan or ethyl-enzyme; or alkaline solvents, such as pyridine or triethyl-35-This paper scale is applicable to China National Standard (CNS) A4 specifications (210 '〆297mm) Please read the precautions first / fill in this page to order B7 5. Invention description (34) Amine. The methods (a) and (b) according to the invention are preferably carried out in the presence of suitable reaction adjuvants. Appropriate reaction aids are all conventional inorganic or organic tests. The following substances are preferably used: alkali metal hydride, hydroxide, alcohol fish, carbonate or bicarbonate, such as sodium oxyhydroxide, sodium methoxide, sodium ethoxide, sodium butoxide, sodium carbonate, potassium carbonate Or sodium bicarbonate; and a third amine, such as triethylamine, N, N-dimethylaniline, bispyridine, N, N-dimethylaminopyridine, diazabicyclooctane (DABC0) , Diazabicyclononene (DBN) or diazabicycloundecene (DBU). When carrying out the methods (a) to (c) according to the invention, the reaction temperature can vary within a considerable range. Generally, the method is carried out at a temperature between 0¾ to + 200TC, preferably at a temperature between 20 · 10〇 to 150¾. For carrying out the methods (a) to (c) according to the invention, generally 1 to 4 moles are used for each mole of formula (Π) retinyl retinyl or formula (IV) succinimide derivatives or formula (V) acetamide derivatives, respectively Ear (preferably 1 to 2 mol) formula (Tong) rayamine derivatives or amine of formula (VI) and, if appropriate, 1 to 3 mol (preferably 1 to 2 mol) reaction adjuvant and, If appropriate, 1 to 10 mols (preferably 1 to 5 mols)> Chemical agent. Du Printed by the Consumer Cooperation Cooperation of the Central Standards Bureau of the Ministry of Economic Affairs (please read the notes on the back of the page to write this page) The above reaction The process and the collection and separation of the reaction products are carried out according to generally known methods (also detailed preparation examples). The active compounds according to the invention have strong microbicidal activity and can actually be used against undesirable microorganisms. The active compounds are suitable It is used as a plant protection product, especially as a fungicide. In plant protection, this fungicide can be used to fight against the root-swollen bacteria net-36-This paper scale is applicable to China National Standards (CNS) A4 specification (210X297 ) B7 5. Description of the invention (35) (Plasmodiophoromycetes), Oomycet es), Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes, and Deuteromycetes. Some may be mentioned as belonging to the genus The pathogenic bacteria of mycobacterial and bacterial diseases are used as examples, but not limited: Pythium species, such as Pythium ultimum; Phytophthora species, such as pathogenic diseases Mildew (Phytophthora infestans); Pseudoperonospora species, such as Pseudoperonospora humu 1 i or Pseudoperonospora cubense; Plasmopara species, such as vines uniaxial Plasmopara viticola; Peronospora species, such as Peronospora pisi or Peronospora brassica; Erysiphe species, such as Erysiphe graminis; Sphaerotheca species (Sphaerotheca species), such as Xanthium monofilament (Sphaerotheca fu1iginea), are printed by the Consumer Cooperative of the Central Bureau of Samples of the Ministry of Economic Affairs. Podosphaera species), such as white and silk single capsule (Podosphaera leucotricha); Venturia species (Venturia species), such as apple black spot bacteria (Venturia -37-This paper scale is applicable to China National Standard (CNS) A4 specification (210X297 Cli) A7 B7 printed by the employee consumer cooperative of the Central Bureau of Standards of the Ministry of Economy V. Description of invention (36) inaequalis); Pyrenophora species, such as Phrenophora teres or Pyrenophora graminea) (sporozoite type: Drechselera, syn: Synechococcus); Cochliobolus species, such as Cochliobolus sativus (conidia type: Drechslera, syn: long Spores); Uromyces species, such as Uromyces appendiculatus; Puccinia species, such as Puccinia recondita; Trichoderma spp. Genus (Til letia species), such as wheat reticulata (Ti11etia caries); Ustilago species (Ustilago species), such as smutt fungus (Ustilago nuda) or oatmeal powdery mildew (Ustilago avenae); film Genus (Pellicularia species), such as Pellicularia Sasaki (Pe11icular ia sasaki i);

Pyricularia genus, such as Pyricularia oryzae; Fusarium species, such as Fusarium culmorum; Botrytis species, such as Botrytis cinerea;. Needles Genus (Septoria species), needle-like needle spores (Septoria -38-the paper size is suitable for China National Standardization (CNS) A4 specification (210X297 mm) (please read the precautions on the back to write this page),- 6 Α7 Β7 3ΰ6δι 5. Description of the invention (37) nodorum); Leptosphaeria species, such as Leptosphaeria nodorum; Cercospora species, such as Cercospora cinerea ( Cercospora canescens); Alternaria species, such as Alternaria brassicae and Pseudocercosporella species, such as Pseudocercosporella herpotrichoides. This active compound is at the concentration required to combat plant diseases The good tolerance to plants makes it necessary to treat the aerial parts of plants, rhizomes and seeds for vegetative propagation, and soil. The active compounds according to the invention can be used particularly successfully against diseases in the growth of fruits and plants, such as against the genus Monofilament, the genus Monocyste or the genus Nitrogen, against cereal diseases, such as against powdery mildew Genus, or used to combat rice diseases, such as resistance to rice fever bacteria. Furthermore, the active compound according to the invention has excellent in vitro activity. Printed by the Beigong Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs, depending on its specific physical and / or chemical properties, the active compound can be converted into custom formulas, such as solutions, emulsions, suspensions, powders, foams, pastes Granules, moisturizers, ultrafine capsules in Zhonghe substances and in coating compositions for seeds, and ULV cold- and warm-mist formulations. These formulations are prepared according to known methods, such as mixing active compounds with fillers, ie liquid solvents, liquefied gas under pressure, and / or solid carriers, optionally using surfactants, ie emulsifiers and / or dispersions Agent, -39-This paper scale is printed in China National Standard (CNS) Α4 specification (210X297 mm). The A7 B7_ is printed by the Employee Consumer Cooperative of the Central Bureau of Economic Affairs of the Ministry of Economic Affairs. 5. Description of the invention (38) and / or foam forming agent . When water is used as a filler, it can also be used, for example, an organic solvent as an auxiliary solvent. Suitable liquid snakes mainly include: aromatics, such as xylene, toluene or alkylnaphthalene, gasified aromatics or gasified aliphatic hydrocarbons, such as gas benzene, gas ethylene or gas ethane, aliphatic hydrocarbons, Such as cyclohexane or paraffin, such as mineral oil fractions, enzymes, such as butanol or glyphosate and its ethers and esters, ketones, such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strong Polar solvents, such as dimethyl methylamine and dimethyl sulfoxide, and water. The liquefied gas filler or carrier means a liquid gas that is gaseous at normal temperature and pressure, such as an aerosol propellant, such as carbamide, butane, propane, nitrogen, and carbon dioxide. Appropriate solid-vegetable carriers are: for example, surface roughness, such as kaolin, clay, talc, white clay, quartz, American activated clay, montmorillonite or diatomaceous earth, and surface synthetic minerals, such as highly dispersed silicic acid, Alumina and silicate. Appropriate solid carriers for granules include: natural crushing and fragmentation, such as calcite, marble, pumice, sepiolite and dolomite 'and synthetic particles of inorganic and organic powder, and organic substances such as sawdust and coconut Granules of husks, corn cobs and tobacco stems. Suitable emulsifying and / or foam-forming agents are: for example, nonionic and anionic emulsifiers, such as polyoxyethylene-fatty acid esters, oxyethylene fatty alcohol ethers, such as aryl aryl ethanedizyme ethers. Disulfonate, emulsified sulfonate, aryl sulfonate, and hydrolysate of prion. Suitable dispersants are: for example lignin sulfite waste water and methyl cellulose. Adhesives such as carboxymethyl cellulose and powdered, granular or lattice polymers such as gum arabic, polyvinyl yeast and polyvinyl acetate, and natural phospholipids such as natural phospholipids can be used in the formulation Brain phospholipids and lecithin, and synthetic lipids. Other additives can be inorganic and vegetable oils. -40-This paper scale is applicable to China National Standard (CNS) Α4 specification (21〇'〆297mm) (Please read the notes on the back to fill out this page) Order_ Printed by the Staff Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs A7 _ _B7 V. Description of the invention (39) Colorants can be used, such as inorganic colorants such as radon iron, titanium oxide and Prussian blue, and organic dyes such as alizarin dyes, azo dyes and metal j cyanine Dyeing department, and trace nutrients such as iron, chrysanthemum, butterfly, steel, beginning, balance, and zinc. The formula contains 〇1 to 95% by weight of active compound, preferably 0.5 to 90%. The active compound according to the present invention can be used directly in the formulation, or it can be used in the form of a mixture with other known bactericides, bactericides, septics, nematodes or insecticides to expand the field of action or Prevent the emergence of resistance. The following are examples of suitable mixtures: Antimicrobial agents:

2-aminobutane; 2-anilino-4-methyl-6-cyclopropyl-pyrimidine; 2 ,, 6'-dibromo-2-methyl-4'-trifluoromethoxy-4 ' -Trifluoromethyl-1,3-thiozole-5-carboxanilide; 2,6-digas-N- (4-trifluoromethylbenzyl) benzamide; (Ε) -2- Methoxyimino-N-methyl-2- (2-phenoxyphenyl) acetamide; 8-hydroxyd quinoline sulfate; (Ε) -2- {2- [6- (2- Cyanophenoxy) pyrimidin-4-yloxy] phenyl} -3-methoxydienoic acid methyl ester; (Ε) -methoxyimino-C a-(o-tolyloxy)- O-Tolyl] methyl acetate; 2-phenylbenzene powder (〇PP); Aldimorph; ampropylfos; aniUzine; azaconazole (azaconaz〇le); benlaxyi (benlaxyi), benadanil (benodanil); benomyl (benomyi); benapic (binapacryl); biphenyl; beittan (bitertano 丨); Patty Sidi-S This paper scale is applicable to China In-House Standard (CNS) A4 specification (210X297 public envy) (please read the precautions on the back and write this page "

* tT A7 B7 Printed by the Consumers ’Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs V. Invention Instructions (40) (blasticidin-S); bromuconazole; broupimate; bupirimate; buthiobate ; Public broken calcium; captafol; captan; carbendazim; carboxin; carnoline; quinomethionate; chnaerob ; Chloropicrin; chlorothalonil; chlozolinate; cufraneb; cymoxanil; cyproconazole; cyproconazole; Cyprofuram; dichlorophen; diclobutrazol; diclofluanid; dicyclomi t # (diclomezin); dicloran; diethyl buddha Carbo (diethofencarb); difennoconazole; dimethirimol; dimethomorph; dimethomorph; diniconazole; dinocap; diphenylamine; diphenylamine; di Mouth A dipyrithion; diitalimfos; di dianianon; dodine; drazoxolon ; Edifenphos; epoxyconazole; ethirimol; etridiazole; fenarimol; fenbuconazole; van aflen (fenfuram); fenitropan; fenpiclonil; fenpropidin; fenpropimorph; fentin acetate; fentin acetate; fentin hydroxide); ferbam; ferimzone; fluazinam; fludioxonil; fluoromide; fluq uinconazole ϊ -42-this paper The standard is applicable to the Chinese National Standard (CNS) A4 (210X2_97mm) Please read the note item Maiding A7 B7 V. Description of the invention (41) Please read the notes on the back of I & fill in this pageFlusilazole (flusilazole) ; Flusulfamide; Flutolanil; Flutriafol; Folpet; Fosetyl-aluminum; Fothylidea (fthalide); Fbada Fuberidazole; furalaxyl; furmecyclox; Kang Junding (quazatine); hexaconazole; hexaconazole; hymexazole; imazalil; imibenconazole; iminoctadine; iberbenfoss (Iprobenfos) (IBP); Iprodi SH (iprodione); isoprothiolane; isoprothiolane; kasugamycin; steel preparations such as copper hydroxide, copper naphthalene, copper gas oxide, copper sulfate, gas Copper, 8-Hydroxy II Chalin, Copper-Bordeaux mixture; Mancopper; Mancozeb; Maneb; Mepanipyrim; Manber Mepronil; metalaxyl; metconazole; methasulfocarb; methasulfocarb; methfuroxam Indochina, the consumer consumption cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs; Manila (metiram) ); Metsufovax; myclobutanile; nickel dimethyl dithiocarbamate; nitro II isopropyl (nitrotha bu isopropyl); nuarimol (nuarimol); over (Ofurace); oxadixyl; oxamocarb; oxycarboxin; perfurazoate; pankang bite (p enconazole); pencycuron; phosdiphen; pimaricin; pimaricin; piperalin; poly 8-alky II; polyoxin; probenazole;普 -43-This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm) B7 5. Description of the invention (42) Prochloraz; procymidone; promomidone; propamocarb; Propiconazole; propineb; pyrazophos; pyrifenox; u biman b pyrnimethanil; pyrimethanil; pyriol quinone (pyr〇fjUii〇n ); Quintozene (PCNB); sulfur and sulfur preparations; tebuconazole; tebuconazole; tecloftalam; tecnazene; tetraconazole; D Thiabendazole; thicyofen; II thiophanate-methyl; thiram; thiram; tolclophos-methyl; Dolly Tolyfluanid; triadimefon; triadimenol; triazoxide; trihloxide ; Tricyclazole; Tridmorph; Triflumizole; Triforin; Triononazole; Trivalonazole; Validamycin A; Vanke Luo Lin (vinci〇z〇iin); Sinaba (zineb); Rerama (ziram). Bactericides: Bronopol; dichlorophen; nitrapyrin; nickel dimethyldithiocarbamate; kasugamycine; osslin (Octhilinone); ○ furan carboxylic acid; oxytetracyclin (oxytetracyclin); probenazole (probenazole); bond lysin; tecloftalam (tecloftalam); sulfuric acid sales and other sales system B7 5. Description of the invention (43) Agent 0 杀虫 # 1 / killer / nematicidal: Abamectin; AC 303 630; Asphate; acrinathrin; acrinathrin; alanycarb; Adi Carba (aldicarb); alphamethrin (alphamethrin); amitraz (amitraz); avermectin (avermectin); AZ 60541; azadirachtin (azadirachtin); Alifeng A (azinphos A); available Azinphos M; azocyclotin; Bacillus thuringiensis; bendiocarb; benfuracarb; benzultacarb; benzultap Severin (bet-acyflnthrin); Baifenlin (bifenthrin); BPMC; Brofenprox (brofenprox); Bromophos A (bromophos A); cloth Carbfen (bufencarb); buprofezin (buprofezin); butocarboxin (butocarboxin); butyl o pidapabon (butylpyridaben); cadusafos (cadusafos); carbaryl (carbaryl); carbaba (carbofuran); carbophenothion; carbosulfan; cartap; CGA 157419; CGA 184699; chloethocarb; chlorethoxyfos; Chlorfenvinphos; chlorfluazuron; chlormephos; chlorpyrifos; chlorpyrifos M; chlorpyrifos M; cis-resmethrin ; Cyclocurin ((: 1 (^ 5 ^ 111 ^ 11); clofentezine); cyanophos; cyanophos; cycloprothrin; cyfluthrin; cyfluthrin; 45 -This paper scale is applicable to the Chinese National Standard (CNS) A4i) l # (210X297mm) A7 _________B7_ V. Description of invention (44) (cyhalothrin); cyhexatin; cypermethrin; cypermethrin (Cyromazine); deltamethrin (deltamethrin); Diman soup M (demeton M); Diman soup S (demeton S); Decoton-S-methyl; Defenton-S-methyl; Diafenthiuron; Diazinon; Diichlofenthion; dichlorfos; dicyclofen (dicl iphos); dicrotophos; diethion; diflubenzuron; dimethoate; dimethylvinphos; second drink (Dioxathion); disulphoton; edifenphos; emamectin; esfenvalerate; ethiofencarb; ethione; ethion Ethofenprox; ethoprophos; etofenprox; etrimphos; fenamiphos; fenamiphos; fenazaquin; fenbutatin Oxide; Fenithion (fenitrothion); Fencarba (fenobucarb); Fenb thiocarba (fenothiocarb); Fenoxycarba (fenoxycarb); Fenpropathrin; Fenpropathrin; Fenpyrad; Fen Poma (fenpyroximate); fen ί sen (fenthion); fenvalerate (fenvalerate); fondon (fipronil); Fu Duan Na (fluazinam); Fuhuan La (fl ucycl〇xuron); flucythrinate; flufenoxuron; flufenprox; fluval inate; fonophos; fumard thain (Formothion); Fosthiazate (Fosthiazate); Fu 46 This paper size is suitable for China National Standard (CNS) A4 specification (210X297 mm). Please read the notes on the back first. Printed by the Employee Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs. 3 ^ 6S〇5 A7 _____B7 V. Description of the invention (45) Bebfenprox; furafencarb; furathiocarb; HCH; heptenophos; hexaflumuron; hexathimur (Hexythiazox); imidacloprid; iprobenfos; isazophos; isofenphos; isoprocarb; isobathone; isoxathion; clothing Van Martin (ivermectin); Lanta-Sailin (1811 ^ (13-.佂 113 丨 〇1: 111 ′ 丨 11); fenfenline (11 ^ 611111 * 011); malathion (malathion); manka companion (mecarbam); muff wind (mevinphos); man sulfur wind (mesulfenphos); Metaldehyde; methacrifos; methamidophos; methidathion; methiocarb; methomyl; methomyl; metolcarb; Milbemectin; monocrotophos; moxidectin; naled; NC 184; NI 25; nitenpyram; omethoate ; Omega (oxamyl) •, oxygen manden M (oxydemeton Μ); oxydeprof (oxydeprofos); for cyane (parathion A); for cyane M (parathion Μ); Bermanslin (permethrin); fens Phenthoate; phorate Printed by the Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economy; phosalone; phosmet; phosmet; phosphamidon; phoxim; than Pirimicarb; pirimiphos M; pirimiphos A; pirimiphos A; profenofos; promecarb; promecarb; propaphos; Proxor; Prothiofos; Prothoate; Bimitrin-47-This paper scale is applicable to China National Standards (CNS) A4 specification (210X297 mm) B7 V. Description of invention (46) (pymetrozin); pyraclofos; pyradaphenthion; pyresmethrin; pyresmethrin; pyrethrum; pyridaben; pyridiben (pyridaben); pyrimidifen); pyriproxifen; quinalphos; RH 5992; salithion; sebufos; silafluofen; sulfotep; Sulprofos; tebufenozid; tebufenpyrad; tebupirimphos; teflubenzuron; teflubenzuron; tefluthrin; de Temephos; terbam; terbufos; tetrachlorvinphos; thiafenox; thiodicarb; thiofanox; sulfur Thiomethon; thionazin; thuringiensin; tralomethrin; triarathen ; Triazophos; triazuron; trichlorfon; triflumuron; trimethacarb; trimethacarb; vamidothion; XMC; Xilika ( xylylcarb); YI 5301/5302; zetamethrin. It is also feasible to print with other known active compounds, such as herbicides, or mixtures with fertilizers and growth regulators, in the Consumer Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs. The active compound can be used alone or in its formulation type or usage form prepared from these formulations, such as immediate solution, suspension, wettable powder, paste -48-This paper size is applicable to China National Mous (CNS) A4 specifications (210XW7mm) A7 ___B7 5. Description of the invention (47) Agents, soluble powders, crumbs and granules are used. They are used by conventional methods, such as water sprinkling, spraying, spraying, spreading, powder spreading, foam application, wiping, etc. The active compound can also be applied via the ultra-low volume method or the active compound formulation or the active compound itself can be injected into the soil, and the seeds of plants can also be treated. When treating plant parts, the concentration of active compound in the use pattern can vary within a relatively wide range. Generally, it is between 1 and 0.0001% by weight, preferably between 0.5 and 0.001% by weight. For the treatment of seeds, generally 0.001 to 50 grams per kilogram of seed is needed, preferably 0.01 to 10 grams of active compound. When treating the soil, an active compound concentration of 0.00001 to 0.1% by weight, preferably 0.0001 to 0.02% by weight, is required in the affected area. Data preparation examples: Example 1: Please read the notes on the back &% write this page) 衣-

, 1T

Printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs (Method b) N-methyl- {2-[(bu (3-trifluoro) in 1.4 grams (3.3 millimoles) in 10 milliliters of dimethylformamide Methylphenyl) ethylene) -aminooxymethyl] -phenyl} -2-methoxyimino-thioacetamide at 401〇 and 1.5 g (10.8 mmol) of potassium carbonate Stir together with 2 grams (14 millimoles) of methyl iodide -49-This paper scale is applicable to the Chinese National Standard (CNS) grid (210X297mm) A7 B7 5. Description of the invention (48) Mix for 3 hours. A mixture containing 1.1 g (13.1 mmol) of O-methyl ammonium vapor in 5 ml of formazan and 1.8 ml of a 2 mol sodium methoxide solution was added to the mixture, after which the reaction mixture was refluxed for 30 minute. The reaction mixture was then poured into water and extracted with ether. After removing the solvent, the residue was chromatographed in ether: petroleum ether = 1: 1 to obtain 0.7 g (48.5% of theoretical value) 1,2 -Bis (methoxyimino) -1-methyl-amino-2- {2-[(1- (3-trifluoromethylphenyl) ethylene) -aminooxymethylphenyl } -Ethane. 1 H NMR (CDC1 3 / tetramethylsilicon): 1005 = 2.283 (3H); 2.824 / 2.842 (3H); 3.788 (3H); 3.978 (3H); 5.019 / 5.037 (1H); 5.215 ( 2H); 7.2-7.6 (6H); 7.757 / 7.784 (1H); 7.847 (1H) ppm. The starting material of creeping (please read the precautions on the back ^ A to write this page) clothing., 11 CF,

S 11-1) 4 The Ministry of Economic Affairs Central Bureau of Precision Industry Beigong Consumer Cooperative Printed 3 g (7.36 mmol) of N-methyl- {2- [Bu (3-trifluoromethylphenyl) ethylene ) -Aminooxymethyl] phenyl} -2-methoxylamino-acetamide and 0.4 g of P4 Si〇 in 30 ml of toluene and refluxed together for 15 minutes. The mixture was filtered and the filtrate was concentrated, after which the residue was chromatographed in ether: petroleum ether == 1: 1. -50-This paper is printed using the Chinese National Standard (CNS > A4 specification (210X297 mm) A7 B7 _ printed by the Staff Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs _ V. Invention Description (49) 2 g (theoretical value 64% > N-methyl- {2- U- (3-trifluoromethylphenyl> ethylene) _aminooxymethyl] phenyl} -2-methoxyimino-thio Acetamide. 1 H NMR (CDC1 3 / Tetramethylsilicon): 100 5 = 2.222 (3H); 3.207 / 3.224 (3H); 3.956 (3H); 5.125 (2H); 7.0-8.0 (8H); 8.65 (1Η) ppm. Example 2

Νλλλλόη (Method a) Add 6.7 ml of 2 mol sodium methoxide solution dropwise to 0.93 g (13.4 mmol) of rented ammonia gas in 7 ml of formazan. 4.5 g (10.6 mmol) {2-[(Bu (3-trifluoromethylphenyl) ethylene) -aminooxymethyl] -phenyl} -2-methoxyimino- Methyl thioacetate was added, and the mixture was refluxed for 15 minutes. The reaction mixture was allowed to stand at room temperature for 24 hours' to remove methanol in the air, after which the residue was distributed between water and ethyl acetate. After removing the solvent, the product was chromatographed in ether: petroleum bond = 1: 1. 2.7 g (60.1% of theoretical value) of plaimidyl-1-methoxy-2-methoxyimino-2- {2-[(Bu (3-trifluoromethylphenyl> ethylene Base) -aminooxymethyl] -phenyl} ethane. This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm) (please !: write this page) 306S65 A7 _ _B7_ 5. Description of the invention (50) 1 H NMR (CDC1 3 / tetramethylsilane): 100 5 = 2.199 (3H); 3.949 (3H); 4.003 (3H); 5.114 (2H); 7.0-7.6 (6H); 7.7-7.9 ( 2Η) ppm. Preparation of starting material

s (11-2) Printed by the Ministry of Economic Affairs, Central Bureau of Industry and Commerce Beigong Consumer Cooperative, 10 g (0.024 mol) {2-〔(1- (3-trifluoromethylphenyl> ethylene) -amine Methyloxymethyl] -phenyl} -2-methoxyimino-acetic acid methyl ester in 50 ml of xylene and 14.9 g (0.036 mole) of the Luisen reagent was refluxed together for 16 hours. Then, another 14.9 g was added (0.036 mol) Lewis reagent, and then the mixture was refluxed for another 16 hours. The mixture was concentrated, and the residue was chromatographed in petroleum ether: tert-butyl methyl ether = 4: 1. 4.2 g (theoretical value of 40.4) %) {2-[(1- (3-trifluoromethylphenyl) ethylene) -aminooxymethyl] -phenyl} -2-methoxyimino-methyl thioacetate. GC / MS: M = 424, 393, 362, 345, 317, 268, 240, 222, 208, 186, 145, 116, 89, 75, 47. Example 3 -52 This paper scale is applicable to the Chinese National Standard (CNS ) A4 specification (210X297mm) A7 B7 5. Description of the invention (51)

(Method a &gt; Add 12 ml of 2-molar sodium methoxide solution in formazan to 2 g (0.024 mol) of 0-methylpyridine in 12 ml of methanol. 8.0 g (0.024 mol> [2- (2-methylphenoxymethyl) -phenyl] -2-methoxyimino-thiothioacetic acid methyl ester was added to the solution, after which the mixture was refluxed for 15 minutes. The reaction mixture was allowed to stand at room temperature for 24 hours, the formazan was removed in the air, and then the residue was distributed between water and ethyl acetate. After the solvent was removed, the residue was placed in ether: petroleum ether = 1 ·· 3 It was chromatographed in 2.1 g (theoretical value 25.5¾) of 1-methoxy-1, 2-bis (methoxyimino) &gt; -2- (2-methylphenoxymethyl) phenyl -Yiyuan. 1 H NMR (CDC1 3 / Tetramethylsilane) printed by the Consumer Labor Cooperative of the Central Standards Bureau of the Ministry of Economic Affairs: 10〇 <5 = 2.288 (3H); 3.761 (3H); 3.968 (3H); 3.980 (3H); 5.005 (2H); 6.783 / 6.811 / 6.842 / 6.866 (2H); 7.05-7.2 (2H); 7.3-7.5 (2H); 7.5-7.6 (1Η) ppm. Others can be similar to the preparation examples and Formula prepared according to the general description of the method of the present invention I) a compound of the Example listed in Table 1: Scale of the present paper is suitable trapped Chinese home registration rubbing (CNS) A4 size (210X297 mm) V. Description of the Invention (Table 52 Example No. CH,

A7B7, 〆〇, △ / E, / X Z Ar c II% (I) Ο—Υ '6

Ar

X Y1 Physical data -OCH2-

-NHCH 3

CH 3

CH3O 1H NMR 2.29 (s)? 3.75 (s) 3.96 (s); 5.05 (s) (Please read the notes on the back before writing this page)

3 H

3 H

3 H) / i / \ — /% 1 / i / * / \ / λ /% 1 »* 'dssss tssssss R # (\ -fv / V / V #fv R / V« fv / V / 1 #f \ R # (v / 1. W83664 W69664 W77 0 0 7 9 0 0 2 7 9 0 89 1h123351h123351h34 Printed by Beigong Consumer Cooperative of Central Bureau of Standards, Ministry of Economic Affairs

This paper scale is applicable to China National Standard (CNS) A4 specification (210X297 mm). V. Description of invention (53 Table 1 Continued A7B7 Example number Printed by the Employee Consumer Cooperative of the Central Central Bureau of Economic Affairs 11 12 13 14 15 ZG Ar EXY丨 0. ch3 och2- -nh2 ch3 〇6 och2- 'eve---nh2 ch3 ύ- och2- Ό--nh2 ch3 CH, och2---nh2 ch3 Ο och2---nh2 ch3 dazzling 92 93 ° C ΧΗ NMR 3.86 (s) 5.01 (s, br) Physical data

XH NMR 3.87 (s)? 4.96 (s, br) ΧΗ NMR 3.67 (s); 6.13 (s, br) Melting point 61 ° C

X • 55 · This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm) A7 B7 V. Description of invention (54) Printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs Η 00 Η Η 猓 Μ 1 〇—〇 η „Work 1 〇1 1 0-0 π ^ ζ 1 ο 1 ο Ί 1 0-0 Bu Gong 1 ο 1 ο Ί Q b Ο &gt; Η 1 I 1 Μ A 1 C0 Ο Ο W 1 Ο η Λ X ϋ «α« UI Κ Office Ο CD • νο \ ο Q Η ms · Η a σ 夕 &gt;? 园 · \ C0 Νμι »&gt; · 一 —Media (please read the precautions on the back before filling in this page) The paper scale is in accordance with the Chinese National Standard (CNS) A4 specification (210X297 mm). V. Description of the invention (55) A7 B7 Printed by the Central Consortium Bureau of the Ministry of Economic Affairs of the Beigong Consumer Cooperative Society hJ Η to Ο H \ p 异 猓 9 1 w T Μ 1 8 W 1 1 RW 1 1 0 — 0 II z 1 0 1 o Ί Ο o &gt; 1 1 1 Μ i Μ § M 1 CO nw XQ sn »u» κί U &gt; • 00 &lt; Λ mw u &gt; • 00 m. · 〇 办 &lt; «— s CD η« ί 1 § ιη &gt; · 1 | Media nf. Mm fn ^^^ 1 In In In ^^ 1 · nn 1 ^ 1 w J.-1¾i ( Please read the notes on the back before filling out this page) This The Zhang scale applies the Chinese National Standard (CNS) A4 specification (210X297mm) -57- A7 B7 V. Description of invention (56) Printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Qing Dynasty κ &gt; KJ OJ to IO 痓 猓 专 οι 1 to Μ 1 〇〇WI * 〇nw 1 1 8 W 1 Ο &gt; h 1 1 1 mk Μ k »〇k K &gt; X Ο W n» w * &lt; U) CD m u &gt; • 00 00 CD • w * U &gt; • 00 S m «· &gt; — &lt;« η «〇2 r circle U CO Sm0f Please read the note on the back of St before filling in this page. The size of the paper for this book is applicable to China National Standard (CNS) A4 (210X297mm) — 58- V. Description of the invention (57) A7 B7 Printed by Beigong Consumer Cooperative of the Central Bureau of Economic Affairs of the Ministry of Economic Affairs to 〇 \ K &gt; tn Instance Number 〇X 〇 &gt; Gong CO N -och2- -och2 -Q b &gt; 1 1 td -nh2 k K) X π u * sw * &lt; LO VD m 3.89 (s); XH NMR (CDC13 / TMS) Please read the notes on Sf before 'fill in this page to order The size of this paper is based on the Chinese National Standard (CNS) A4 (2IOX297mm) 3〇865865 B7 A7 5. Description of the invention (58) Example 16 25 grams (0.0609 mole) The compound

s CH, at room temperature, 28.9 g of 80% strong 3-gas peroxybenzoic acid (0.134 mol) was stirred together in 244 ml of digas methane for 12 hours ❶ The solid content was filtered out, the wall was concentrated, and then Use Shijiu on Shixijiao: Petroleum bond = 1: 1 Chromatograph the residue. After removing the eluent, 13 g (48.2% of theory) was obtained. Example 17 Dissolve 2.9 g (0.00707 mol) in 60 ml of formazan in the following compound (please read the notes on the back ^ so write this page) 衮-

* 1T

CH

Printed by the Beigong Consumer Cooperative of the Central Standard Falcon Bureau of the Ministry of Economic Affairs N- ° xJ〇 η person. Add dropwise to a solution containing 2.2 grams (0.00358 moles) of oxone in 16 milliliters of water. The mixture was stirred at room temperature for 4 hours, methanol was removed, the residue was extracted with ethyl hexanoate, ethyl acetate was removed, and then the residue was extensively analyzed on silica gel with a second pass. After removing the eluent, get 1.6 grams (Li-60 paper size is suitable for China) A · (plus x297 Gongsha)

A7 B7 V. Description of the invention (59) 53.1% of the value). Example 18 0.136 g (0.0020 mol) of imidazole was dissolved in 2 ml of dimethylformamide. After adding 0.12 g (0.002 mol> 40% strong sodium hydride) to the industry, the mixture was stirred at room temperature for 10 minutes, and then 0.88 g (0.002 mol) of the following compound was added and the mixture was allowed to stand at room temperature for 2 days. It was then poured into water and extracted with ethyl acetate, and the solvent was removed to obtain 0.75 g (90% of theoretical value). Example 19 of the preparation of starting material Place 10 g (0.0273 mol) in 50 ml of toluene of the following compound (Please read the precautions on the back I fill in this page)

Printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs and reflowed with 2.4 grams (0.00539 mole) of phosphorus pentasulfide for 10 minutes. The sludge precipitate was removed by zeal analysis, and then the liquid phase was concentrated in the air. Immediately apply the crude intermediate with the following formula. The paper size is applicable to the Chinese National Standard (CNS) A4 specification (210X297mm) B7 V. Invention description (60) B7

Combined with 7.6 g (0.055 mol) of potassium carbonate and 4.2 g (0.0272 mol) of diethyl sulfate in 55 ml of acetone, the mixture was stirred at room temperature for 2 hours. After removing acetone, the residue was chromatographed on silica gel using ether: petroleum ether = 1: 3. After removing the eluent, Yuye obtained 3 grams (26.8¾ of theoretical value). Example 19a

Printed by the Beigong Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs. Dissolve 10 g (0.0296 mol) in 100 mL of ether with a compound of the formula

Pour into 6.2 g (0.0298 mol) of penta-vaporized phosphorus, and then stir the mixture at room temperature for 10 minutes. Pour the solution into a solution containing 5 grams (0.06 mol) of 0_methyl 62-the paper size is used in China National Standard (CNS &gt; A4 specification (210X297mm) A7 B7 V. Invention description (61)) Amine hydrogen acid barium, 30 g (0.217 mol) potassium carbonate, 100 g ice and 50 g water. The mixture was stirred vigorously for 15 minutes, after which the ether phase was separated and extracted again with ether. After the solvent, 10.25 g of 80% pure crystals (75% of the theoretical value) are obtained. Example 19b n- mn ml tn (please read the notes on the back to write this page) Put 27 g (0.0769 mol) under Compound of formula

Order

Printed by the Employee Consumer Cooperative of the Central Standard Falcon Bureau of the Ministry of Economic Affairs. Dissolved in 150 ml of methanol, added 13.7 g (0.154 mol) of 45% strong sodium hydroxide aqueous solution, and then the mixture was stirred at 60¾ for 1 hour. Methanol was removed, and the mixture was acidified with hydrogen acid, after which the acid was extracted with digaseous methyl ketone. After removing the solvent, 20.8 g (theoretical value of 80.2¾) was crystallized. Example 19c 9.8 g (0.087 mol) of potassium tributyrate was dissolved in 90 ml of dimethylformamide. Add 17.7 g (0.087 mol) 3-trifluoromethyl acetophosphenone 0 at 0eC, and then add 20 g (0 * 087 mol) -63 This paper size can be easily used by the Chinese National Standard ( CNS) Eight 4 specifications (210X297 public daughter) A7 ______B7 one ____ V. Description of the invention (62) 2-bromoethyl-benzoic acid methyl vinegar. Next, the mixture was stirred under the chamber for 2 hours, dimethylformamide was distilled off in the air, and then the residue was distributed between ethyl acetate and water. After removing ethyl acetate, 29.6 g (96.5¾ of theory) of the compound of the formula

Printed at 170 to 1751C, 0.5 torr, the employee consumer cooperative of the Central Standards Bureau of the Ministry of Economic Affairs can be steamed to obtain esters. Example of Standard Use Meeting A? YA 1 ^ 01131 ^ 3 Test (Rice) / Protective Solvent: 12.5 parts by weight of acetone emulsifier: 0,3 parts by weight of alkyl-aryl zhongdi> alcohol is the preparation of active compounds For an appropriate formulation, 1 part by weight of active compound is mixed with the amount of solvent, and then the concentrate is diluted with water and the amount of emulsifier to the desired concentration. To test for protective activity, young rice plants are sprayed with the active compound preparation until dripping. After the spray coating industry has dried, the plants are inoculated with an aqueous suspension of spores of rice fever bacteria. The plants are then placed in a greenhouse at 100% relative atmospheric humidity and 25 ° C. Evaluation of disease infection was conducted 4 days after vaccination. In this test, for example, preparation of the compound of Example 4 at 0.025¾ activity _ 64-please read the notes on the back first: fill in this page) Zhuan ·

、 1T This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 public daughter) A7 _____ B7 V. Description of the invention (63) The effectiveness of the temporal concentration of 89¾ at the concentration of sexual compounds.

Example B Powdery mildew test (wheat) / therapeutic solvent: 10 parts by weight of N-methylophthalocyanine emulsifier: 0.6 parts by weight of emulsyl-aryl glycerol eyebrow. 1 part by weight of the active compound is mixed with the amount of solvent and emulsifier, and then the concentrated wall liquid is diluted with water to test the therapeutic activity, and the young plants are sprinkled with spore powder of powdery mildew f $ p tritici. 48 hours after inoculation, the plants are sprayed with the preparation of active compound at the given application rate. Place the plant in a greenhouse at a temperature of about 20¾ and a relative atmospheric humidity of about 80¾ to promote the growth of powdery mildew. 7 days after seeding. In this test, for example, the compound of Example 4 was prepared, and at an active compound concentration of 250 g / ha, an effectiveness of 100¾ was achieved.

Example C Test of Powdery Mildew (Barley) / Therapeutic Solvent Printed by the Beigong Consumer Cooperative of the Central Bureau of Samples of the Ministry of Economic Affairs / Therapeutic Solvent: 10 parts by weight of N-methylpyrrolidone emulsifier: 0.6 parts by weight of aryl aryl glycol Ether is a suitable preparation for preparing an active compound. 1 part by weight of the active compound is mixed with the amount of solvent and emulsifier, and then diluted with water to a desired concentration. In order to test the therapeutic activity, sprinkle the young plants in the He white powder box f. Sp. 65-This paper scale is used in China National Standard (CNS) A4 specification (210X297mm)

306S6S A7 -------- B7___ V. Description of the invention (64) Spore powder of hordei. 48 hours after inoculation, the plants are sprayed with the preparation of active compound at the given application rate. The plants are placed in a greenhouse at a temperature of about 20¾ and a relative atmospheric humidity of about 80% to promote the formation of powdery mold adenospores. The assessment is performed 7 days after the inoculation. In this test, for example, the compound of Example 4 was prepared, and it showed an effectiveness of 100¾ at an active compound concentration of 250 g / ha.

Example D Powdery mildew test (wheat) / protective solvent: 10 parts by weight of N-methylopyrrolidone emulsifier: 0.6 parts by weight of emulsified aryl polyglycerol ether is an appropriate preparation for preparing active compounds, 1 part by weight of active compound is mixed with the stated amount of solvent and emulsifier, after which the concentrate is diluted with water to the desired concentration. To test for protective activity, young plants are prepared with the active compound at a given application rate. After drying in the spray coating industry, the plants are sprinkled with spore powder of powdery mildew f. Sp. Tritici. The plant is placed in an overflow chamber at a temperature of about 20¾ and a relative atmospheric humidity of about 80% to promote the formation of powdery mold spores. The assessment is performed 7 days after the inoculation. In this test, for example, the compound of Example 4 was prepared, and at the active compound concentration of 250 g / ha, the effectiveness of the status quo is shown.

Example E Powdery mildew test (barley) / Protection-66-This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (21〇Χ297 mm) 306865 A7 _B7 5. Description of the invention (65) Solvent: 10 parts by weight N- Methylpyrrolidone emulsifier: 0.6 parts by weight of alkylaryl polyglycol ether is an appropriate preparation for preparing an active compound. 1 part by weight of active compound is mixed with the amount of solvent and emulsifier, and then diluted with water and concentrated Liquid to the desired concentration. To test for protective activity, young plants are given a preparation of active compound at a given application rate. After drying in the spray coating industry, the plants are sprinkled with the powder of spores of powdery mildew f. Sp. Hordei. The plants are placed in a greenhouse at a temperature of about 20¾ and a relative atmospheric humidity of about 80% to promote the formation of powdery mold spores. The assessment is performed 7 days after the inoculation. In this test, for example, the compound of Example 4 was prepared, and it showed an effectiveness of 100% at an active compound concentration of 250 g / ha.

Example F Monofilament test (courgette) / protective solvent: 4.7 parts by weight of internal ketone emulsifier: 0-3 parts by weight of emulsyl-aryl glycidyl ether. For proper preparation of the active compound, 1 part by weight The active compound is mixed with the stated amount of solvent and emulsifier, after which the concentrate is diluted with water to the desired concentration. Printed bags of the Consumer Cooperatives of the Central Bureau of Standards of the Ministry of Economic Affairs To test the protective activity, young plants are sprayed with the active compound preparation until they drip. After the spray coating layer is dried, the plants are sprinkled with conidiophore powder of Xanthium monofilamenta. Then, the plants are placed at 23 to 24¾ and about 75¾ relative atmospheric humidity. The paper scale applies the Chinese National Standard (CNS) A4 specification (210X297 mm). The A7 B7 is printed by the Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs. 66) Under the greenhouse. The assessment is performed 10 days after the inoculation. In this test, for example, the compounds of Preparation Examples ⑵, ⑷, and (11) showed up to 100% effectiveness.

Example G The test of the single-shell shell of the yam filament (apple) / protective solvent: 4.7 parts by weight of acetone emulsifier: 0.3 parts by weight of emulsyl-aryl polyglycol ether. The compound is mixed with the stated amount of solvent and emulsifier, after which the concentrate is diluted with water to the desired concentration. To test for protective activity, young plants are sprayed with the active compound preparation until dripping. After the spray coating industry is dried, the plants are inoculated with conidia powder sprinkled with the pathogenic bacteria of apple mold (Baiyousi single capsule). Then, the plants are placed in a greenhouse at 23¾ and about 70% relative atmospheric humidity. The assessment was conducted 9 days after the inoculation. In this test, for example, the compounds of Examples ⑵, ⑷, (11) and (17) were prepared, and the effectiveness was as high as 100%. Example Η Aspergillus test (apple) / protective solvent: 4.7 parts by weight of copper propyl emulsifier: 0.3 parts by weight of alkyl aryl polyglycol ether. To prepare a suitable preparation of the active compound, 1 part by weight of active compound -68 -This paper scale is applicable to China National Standard (CNS) Α4 specification (210X297mm) (please read the notes on the back before reading this page) Yi ·, 1Τ Printed A7 by Beigong Consumer Cooperatives, Central Bureau of Economic Affairs, Ministry of Economic Affairs B7 V. Description of the invention (67) Mix with the stated amount of solvent and emulsifier, and then dilute the concentrated solution with water to the required concentration. To test for protective activity, young plants are swallowed with the preparation of active compound until dripping. After the spray coating has dried, the plants are inoculated with an aqueous suspension of conidia of the apple-pathogenic bacteria (Acer malaria) and then placed in a culture room at 100% relative atmospheric humidity and 20 ° C for 1 day The plants are then placed in a greenhouse at a relative atmospheric humidity of about 70% and 20.0. Evaluation is performed 12 days after inoculation. In this test, for example, the compounds of Examples ⑵, ⑷, and (11) were prepared, It is up to 100¾ effective. 69 This paper scale is suitable for China National Standard (CNS & A4 specification (210X297mm)

Claims (1)

A8 Announcement i VI. Application for Patent Scope Patent Application No. 84101341 ROC Patent Appln. No. 84101341 Amended Patent Application Chinese Text-Annex (Amended Claims in Chinese-Enel. (I) (民国 'February 2, 86 Submitted) ~~ (Submitted on February, 1997) J · oxime derivatives of formula (I) z, G, ArE, c / X II (please read the notes on the back before filling this page) ------ -{Binding. Order where Ar stands for phenylene, E stands for a direct bond or the following group: Among them enn N 2 R Printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs R2 stands for alkoxy with 1 to 4 carbon atoms , G represents _0CH2_ or the following group: -C (R4) = N-0-CH2- where R4 represents an alkyl group with 1 to 4 carbon atoms, X represents -OX1, -SX1, -SOX1, -SO2X1 -NX2P or Misaki 70 97-9bayer.240a-S This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm). Six, patent application range VZ A8 B8 C8 D8 base, where X1 stands for 1. to 4 An alkyl group of carbon atoms, X2 and X3 independently represent hydrogen or an alkyl group having 1 to 6 carbon atoms represents hydrogen, or represents a group having 1 to 4 The alkyl group of a carbon atom represents a phenyl group, a phenyl group substituted by a substituted alkyl group, a phenyl group or an octyl group optionally substituted by a # group, a G-Ce alkyl group, a G-Q alkyl group or a substituted alkyl group. 2 For example, the compound of formula (I) in item 1 of the patent application, where Ar represents ortho-, meta- or para-phenylene, and Ε represents the following group: Ν. R2 Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs Print G where R2 represents methoxy or ethoxy and represents -0CH2_ or the following group: -C (R4) = N-0-CH2- where R4 represents methyl, ethyl, n- or iso-propyl Base, or positive; * -r- iso- or second-butyl, 1 division 々 71 due to the home standard (CNS) Ba Na (27 ^^-Su6S65 A8 B8 C8 D8 VI. Patent application Central Standard of the Ministry of Economy Bureau employee consumer cooperatives printed X represents _0χι, -SX〗, -S0X1, -SO2X1, -NPX3 or imidyl group, where χ1 represents methyl, ethyl, n- or iso-propyl, or n-, iso , Second- or third-butyl, X2 and X3 independently of each other represent hydrogen, or represent methyl, ethyl, n- or iso-propyl or n-, iso-, second- or third-butyl Radical, ν represents hydrogen, or methyl, ethyl, n- or iso-propyl or n-, iso-, second- or third-butyl, 1 represents selectively fluorine, gas, bromine, methyl Group, ethyl, n- or iso-propyl, or n- -, Iso-, second- or third-butyl, methoxy, ethoxy, n- or iso-propoxy or trifluoromethyl substituted phenyl, azulenyl or fluoro, fluoro or bromo Substituted bases. 3. For example, the compound of formula (丨) in item 1 of the patent application, where Ar represents ortho-phenylene, and E represents the following group: in which IS (please read the precautions before Fill in this page) Pack. Order. Cnn Ν 2 R 306865 A8. B8 C8 D8 々 printed by the Employee Consumer Cooperative of the Central Bureau of Standards of the Ministry of Economic Affairs. The patent application scope R2 represents methoxy, G represents -0CH2- or the following group: -C (R4) = NO-CH2- where R4 Represents methyl or ethyl, X represents -0Γ, -SXi, -SOX, -SO2X1, -NX2X3 or imidazole, wherein X1 represents methyl, ethyl, n- or iso'propyl or n-, iso -, Second- or third-butyl, X2 and X3 independently of each other represent hydrogen, or represent methyl, ethyl, n- or isopropyl or n-, iso-, second or third 'butyl , Y1 represents hydrogen, or represents methyl, ethyl, n- or iso-propyl or n-, iso-, second- or third-butyl, z represents selectively fluorine, gas, bromine, methyl , Ethyl, n- or iso-propyl, n-, iso-, second, or third-butyl, methoxy, ethoxy, n- or iso-propoxy or trifluoromethyl Substituted phenyl or pyridyl substituted with fluorine, gas or bromine. 4. A method for preparing a compound of formula (I) such as item 1 of the scope of patent application, which includes a) installing a thiosulfonyl derivative of formula (I) (please read the precautions on the back before filling this page). Set This paper wave scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm). Patent scope A8 B8 C8 D8 Z / G, Ar, E, c / 〇 (S) X1 II s (ii) where Ar, E, G , X 1 and Z have the hydroxylamine derivative of the formula (ID) given in item i of the patent scope I 'Η 2 Ν-0-γ (ΙΠ) where Υ1 has the aforementioned definition, or its acid addition salt, if appropriate In the presence of a diluent and if appropriate in the presence of a reaction auxiliary, to carry out the reaction; or b) the formula (IV) acetamide derivative / G, / NHX Ar '' c II s (IV)-? ---- ---- {装 I. (Please read the notes on the back before filling in this page. J Among them, the Central Consumer Standardization Bureau of the Ministry of Economic Affairs printed the Ar, E, G, X3 and Z with the patent application of the 1st place. Give a definition, emulsify it according to the conventional method, and then the obtained imine derivative of formula (IVa) NX Z / G, Ar, E, C々IS Aik (IVa) 74 This paper standard is applicable to the Chinese National Standard (CNS ) A4 specification (210X297 gong) Α8 Βδ C8 D8 The scope of patent application where Ar 'Ε, G, Χ3 and ζ have the aforementioned definitions, and Aik represents alkyl, preferably methyl, if Without separation, react with the hydroxylamine derivative of formula (1Π) or its acid addition salt if appropriate in the presence of a diluent and if appropriate in the presence of a reaction aid; or c) transfer the formula (V) amide Derivatives 7 / GE, / ΝΗ-Ο-Υ1 Z Ar c II s (V) where Ar, E, G, Y 1 and Z have the definitions given in item 1 of the patent application scope are alkylated according to conventional methods, and then The obtained formula (Va) oxime N ⑽Ο — YA S Aik (Va) J ---------- ^ 袈-(please read the precautions on the back before filling in this page) -3- of which the Ministry of Economy The Central Standard Bureau ’s employee consumer cooperatives print Ar, E, G, Υ 1 and Aik with the aforementioned definitions, if appropriate without separation, and the formula (VI) amine HNX 2 X 3 (VI) where X2 and X3 have the aforementioned definitions, if Properly react in the presence of diluent 75 This paper scale is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm> A8 B8 C8 D8 Printed by the Ministry of Economic Affairs Central Standards Bureau Employee Consumer Cooperative 306S65 Patent application scope 5 kinds of counts including at least-such as towels The compound of formula (I) as claimed in item 1 of the scope. A Bian method against candida, in which the compound of formula (I), as claimed in item 3 of the patent scope, acts on candida and / or its environment. 7. A method for preparing a fungicide, which comprises mixing a compound of formula (I) as claimed in any one of claims 1 to 3 with a filler and / or a surfactant. 76. This The paper size is applicable to the Chinese national standard (CNS & A4 specifications (210X297mm) (please read the precautions on the back before filling in this page)