TW202334088A - 固體形式 - Google Patents

固體形式 Download PDF

Info

Publication number
TW202334088A
TW202334088A TW111134009A TW111134009A TW202334088A TW 202334088 A TW202334088 A TW 202334088A TW 111134009 A TW111134009 A TW 111134009A TW 111134009 A TW111134009 A TW 111134009A TW 202334088 A TW202334088 A TW 202334088A
Authority
TW
Taiwan
Prior art keywords
powder
diffraction pattern
ray diffraction
characteristic
degrees
Prior art date
Application number
TW111134009A
Other languages
English (en)
Chinese (zh)
Inventor
何紅燕
蔣思懿
厄爾 舒維特
帕斯卡 道特
勞夫 杜當
妮可 烏登拜奇
歐勒夫 葛拉斯曼
Original Assignee
美商瑞沃３腎臟公司
瑞士商赫孚孟拉羅股份公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202111049581.4A external-priority patent/CN115772123A/zh
Application filed by 美商瑞沃３腎臟公司, 瑞士商赫孚孟拉羅股份公司 filed Critical 美商瑞沃３腎臟公司
Publication of TW202334088A publication Critical patent/TW202334088A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
TW111134009A 2021-09-08 2022-09-08 固體形式 TW202334088A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN202111049581.4 2021-09-08
CN202111049581.4A CN115772123A (zh) 2021-09-08 2021-09-08 固体形式
US202163243813P 2021-09-14 2021-09-14
US63/243,813 2021-09-14

Publications (1)

Publication Number Publication Date
TW202334088A true TW202334088A (zh) 2023-09-01

Family

ID=83594511

Family Applications (1)

Application Number Title Priority Date Filing Date
TW111134009A TW202334088A (zh) 2021-09-08 2022-09-08 固體形式

Country Status (7)

Country Link
US (3) US11814354B2 (https=)
EP (1) EP4399201A1 (https=)
JP (1) JP2024533420A (https=)
AU (1) AU2022342069A1 (https=)
CA (1) CA3231117A1 (https=)
TW (1) TW202334088A (https=)
WO (1) WO2023039063A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11814354B2 (en) 2021-09-08 2023-11-14 River 3 Renal Corp. Solid forms

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA107088C2 (xx) 2009-09-11 2014-11-25 5-(3,4-дихлорфеніл)-n-(2-гідроксициклогексил)-6-(2,2,2-трифторетокси)нікотинамід і його солі як засоби, що підвищують концентрацію лвщ холестерину
WO2012031817A1 (en) 2010-09-09 2012-03-15 F. Hoffmann-La Roche Ag Determination of abca1 protein levels in cells
US20120101282A1 (en) 2010-10-22 2012-04-26 Pascal Dott Process for the preparation of nicotinamide derivatives
WO2014180741A1 (en) 2013-05-06 2014-11-13 F. Hoffmann-La Roche Ag Methods of identifying modulators of osbpl7 and the use of such modulators for treatment of diseases associated with osbpl7
US20200085810A1 (en) * 2018-07-26 2020-03-19 Hoffmann-La Roche Inc. Compounds for use in treating kidney disorders
US11814354B2 (en) 2021-09-08 2023-11-14 River 3 Renal Corp. Solid forms

Also Published As

Publication number Publication date
US20250263378A1 (en) 2025-08-21
WO2023039063A1 (en) 2023-03-16
JP2024533420A (ja) 2024-09-12
US11814354B2 (en) 2023-11-14
CA3231117A1 (en) 2023-03-16
US20240300895A1 (en) 2024-09-12
AU2022342069A1 (en) 2024-03-14
US20230242485A1 (en) 2023-08-03
EP4399201A1 (en) 2024-07-17
US12134599B2 (en) 2024-11-05

Similar Documents

Publication Publication Date Title
JP7797575B2 (ja) ７ｈ－ピロロ［２，３－ｄ］ピリミジンｊａｋ－阻害剤
US20160214939A1 (en) Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
US9073899B2 (en) Solid forms of dabigatran etexilate mesylate and processes for their preparation
CN105189513A (zh) 葡萄糖醇，1-脱氧-1-(甲胺基)-,1-(6-氨基-3,5-二氟吡啶-2-基)-8-氯-6-氟-1,4-二氢-7-(3-羟基氮杂环丁烷-l-基)-4-氧-3-喹啉羧酸盐的结晶形态
AU2017304779B2 (en) Salts of 2, 6-dimethylpyrimidone derivatives and uses thereof
TW202334088A (zh) 固體形式
KR20250009492A (ko) Tyk2 억제제의 결정질 형태 및 그의 용도
US20240199645A1 (en) Polymorphic forms of (s)-12-fluoro-4-(1-methyl-1h-pyrazol-5-yl)-7a,8,13,14-tetrahydro-7h-[1,2,4]triazolo[4',3':1,6]pyrido[3,2-b]benzofuro[4,3-fg][1,4]oxazonine
US20240368185A1 (en) Macrocyclic azolopyridines
TW202421122A (zh) Tyk2抑制劑之晶型及其用途
CN115772123A (zh) 固体形式
CA2934456C (en) Fused heterocyclic compounds as ion channel modulators
WO2026008074A1 (zh) 补体因子b抑制剂的晶型、其制备方法及用途
KR20250083536A (ko) Tyk2 억제제의 결정질 형태 및 그의 용도
HK1225728A1 (en) Fused heterocyclic compounds as ion channel modulators