TW202237637A - 用於多發性骨髓瘤之ｂｃｍａ標靶ｃａｒ－ｔ細胞療法 - Google Patents
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| PCT/CN2020/133598 WO2022116086A1 (en) | 2020-12-03 | 2020-12-03 | Bcma-targeted car-t cell therapy for multiple myeloma |
| WOPCT/CN2020/133598 | 2020-12-03 |
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| AU2020378263A1 (en) | 2019-11-05 | 2022-06-23 | Janssen Biotech, Inc. | BCMA-targeted CAR-T cell therapy of multiple myeloma |
| CN116096498A (zh) * | 2020-05-04 | 2023-05-09 | 生物诊断有限公司 | 诊断设备 |
| WO2024146398A1 (zh) * | 2023-01-04 | 2024-07-11 | 北京艺妙神州医药科技有限公司 | 分离的抗体、包含该抗体的car及其用途 |
| WO2024206329A1 (en) | 2023-03-27 | 2024-10-03 | Modernatx, Inc. | Nucleic acid molecules encoding bi-specific secreted engagers and uses thereof |
| CA3205511A1 (en) * | 2023-04-19 | 2025-03-17 | Janssen Biotech, Inc. | Bcma-targeted car-t cell therapy for multiple myeloma |
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| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| CA2096222C (en) | 1990-11-13 | 1998-12-29 | Stephen D. Lupton | Bifunctional selectable fusion genes |
| WO1994028143A1 (en) | 1993-05-21 | 1994-12-08 | Targeted Genetics Corporation | Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene |
| US5814618A (en) | 1993-06-14 | 1998-09-29 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| US5464758A (en) | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| US5885827A (en) | 1996-01-23 | 1999-03-23 | The Regents Of The Universtiy Of California | Eukaryotic high rate mutagenesis system |
| FR2814642B1 (fr) | 2000-10-03 | 2005-07-01 | Ass Pour Le Dev De La Rech En | Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee |
| BRPI0807952A2 (pt) | 2007-02-20 | 2014-06-10 | Anaptysbio Inc | Sistemas de hipermutação somática |
| CN105384825B (zh) * | 2015-08-11 | 2018-06-01 | 南京传奇生物科技有限公司 | 一种基于单域抗体的双特异性嵌合抗原受体及其应用 |
| CN105777911B (zh) * | 2016-04-12 | 2019-07-02 | 上海优卡迪生物医药科技有限公司 | 抗bcma嵌合抗原受体、编码基因、重组表达载体及其构建方法和应用 |
| SG10202012157QA (en) * | 2016-06-07 | 2021-01-28 | Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft | Chimeric antigen receptor and car-t cells that bind bcma |
| EP4282877A3 (en) * | 2016-08-10 | 2024-02-21 | Legend Biotech Ireland Limited | Chimeric antigen receptors targeting bcma and methods of use thereof |
| CN108276493B (zh) * | 2016-12-30 | 2023-11-14 | 南京传奇生物科技有限公司 | 一种嵌合抗原受体及其应用 |
| CN108395478A (zh) * | 2017-02-04 | 2018-08-14 | 上海恒润达生生物科技有限公司 | 靶向bcma的嵌合抗原受体并对其双重修饰的方法及其用途 |
| CN119529091A (zh) * | 2018-06-19 | 2025-02-28 | 南京传奇生物科技有限公司 | 工程化的细胞及其用途 |
| JP2021532742A (ja) * | 2018-07-26 | 2021-12-02 | ナンジン レジェンド バイオテック カンパニー, リミテッドNanjing Legend Biotech Co., Ltd. | Ｎｅｆを含むｔ細胞及びその生成方法 |
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| MA71426A (fr) | 2025-04-30 |
| WO2022117068A1 (en) | 2022-06-09 |
| MX2023006371A (es) | 2023-07-31 |
| US20220265710A1 (en) | 2022-08-25 |
| CN116888147A (zh) | 2023-10-13 |
| JP2023551877A (ja) | 2023-12-13 |
| UY39555A (es) | 2022-06-30 |
| KR20230118556A (ko) | 2023-08-11 |
| WO2022116086A1 (en) | 2022-06-09 |
| CA3203603A1 (en) | 2022-06-09 |
| EP4255450A1 (en) | 2023-10-11 |
| AU2021392708A1 (en) | 2023-06-22 |
| IL303312A (en) | 2023-07-01 |
| AR124248A1 (es) | 2023-03-01 |
| US20240000836A1 (en) | 2024-01-04 |
| JOP20230122A1 (ar) | 2023-05-30 |
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