TW202203869A - A photo-biomodulation device with red light and near-infrared light for the eyes and the method thereof - Google Patents

A photo-biomodulation device with red light and near-infrared light for the eyes and the method thereof Download PDF

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TW202203869A
TW202203869A TW109124588A TW109124588A TW202203869A TW 202203869 A TW202203869 A TW 202203869A TW 109124588 A TW109124588 A TW 109124588A TW 109124588 A TW109124588 A TW 109124588A TW 202203869 A TW202203869 A TW 202203869A
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light
band
infrared light
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red light
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TWI722945B (en
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林芸萱
黃士銘
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長庚醫療財團法人基隆長庚紀念醫院
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Abstract

The invention is a photo-biomodulation device with red-light and near-infrared light for the eyes and the method thereof. The device activates the retina and optic nerve of the eyes through delivering low energy red light or near-infrared light.

Description

具紅光及近紅外光多波段眼部活化裝 置及其操作方法 Multi-band eye activation device with red and near-infrared light settings and how to operate

本發明係一種具紅光及近紅外光多波段眼部活化裝置及其操作方法,為一種具有紅光及近紅外光之多波段發光二極體或雷射之眼部視網膜及視神經活化裝置及其操作方法。 The present invention relates to a multi-band eye activation device with red light and near-infrared light and an operation method thereof, and is an eye retina and optic nerve activation device with multi-band light-emitting diodes or lasers with red light and near-infrared light. its operation method.

於人體的眼睛結構中,目前已知視網膜以及視神經是影響人眼視力最重要的眼睛組織。而當罹患各式的視網膜疾病時,例如老年性黃斑部病變,糖尿病視網膜病變,視網膜色素失養症等,以及青光眼,弱視,或是其他視神經病變時,都會使得病人的視力或是視野嚴重下降,甚至嚴重影響人的生活功能以及社會生活能力。 Among the human eye structures, it is currently known that the retina and the optic nerve are the most important eye tissues that affect human vision. When suffering from various retinal diseases, such as age-related macular degeneration, diabetic retinopathy, retinitis pigmentosa, etc., as well as glaucoma, amblyopia, or other optic neuropathy, the patient's vision or visual field will be severely reduced. , and even seriously affect people's life function and social life ability.

而目前視網膜疾病的主要的治療方式,係為於眼球內注射抗血管生長因子,但其治療花費相當高,且因其注射後,受注射者的的反應難以預估,甚至產生嚴重後遺症,至今尚無法視為完美的治療方式。 At present, the main treatment method for retinal diseases is intraocular injection of anti-angiogenic growth factor, but the cost of treatment is quite high, and after injection, the reaction of the injected person is difficult to predict, and even serious sequelae occur. It is not yet considered a perfect treatment.

此外,由於至今仍無法以有效的治療方式治療視神經病變而改善病人的視力,主要因為視神經病變各種原因,導致視神經變性,失去傳導功能,而最終使得視物模糊甚至眼睛失明。而前述視神經病變發病機制,則是因供應視盤的小血管發生缺血性病變,致使視盤局部供血不足所致。 In addition, there is still no effective treatment for optic neuropathy to improve the patient's vision, mainly due to various reasons of optic neuropathy, resulting in degeneration of the optic nerve, loss of conduction function, and eventually blurred vision or even blindness. The aforementioned pathogenesis of optic neuropathy is caused by ischemic lesions of the small blood vessels supplying the optic disc, resulting in insufficient blood supply to the optic disc.

經由前述的說明,可知一但眼睛產生病變,不僅治療費用高昂,且因缺乏完善的治療方法,使得眼睛病變非能完全治癒,更甚者,很可能因失去視力而影響生活甚距,由此可知眼睛的居家一般保養便相對地十分重要。倘若能開發出便於使用者於家中運用的居家眼科光療設備,且該眼科光療設備能具有提升視力的效果,更可滿足使用者的眼睛居家防護以及眼部保健的需求。 From the above description, it can be seen that once the eyes have lesions, not only the treatment cost is high, but also due to the lack of perfect treatment methods, the eye lesions cannot be completely cured, and even worse, it is likely to affect life due to loss of vision. It can be seen that the general maintenance of the eyes at home is relatively important. If a home ophthalmic phototherapy device that is convenient for users to use at home can be developed, and the ophthalmic phototherapy device can have the effect of improving eyesight, it can also meet the user's needs for eye protection at home and eye care.

有鑑於前述,業界確實需要能夠滿足使用者居家防護以及眼部保健需求,得以提升改善視力效果的居家眼科光療設備,該眼科光療設備更為居家生活者所期待。 In view of the above, the industry really needs a home ophthalmic phototherapy device that can meet the user's home protection and eye care needs, and can improve the effect of improving eyesight.

本發明係一種具紅光及近紅外光多波段眼部活化裝置及其操作方法,為一種具有紅光及近紅外光之多波段發光二極體或雷射之眼部視網膜及視神經活化裝置及其操作方法。 The present invention relates to a multi-band eye activation device with red light and near-infrared light and an operation method thereof, and is an eye retina and optic nerve activation device with multi-band light-emitting diodes or lasers with red light and near-infrared light. its operation method.

本發明之一種具紅光及近紅外光多波段眼部活 化裝置,係屬一種運用低能量光療的技術領域,尤指一種利用具紅光及近紅外光波段之發光二極體或雷射所組成的視網膜及視神經活化裝置,其原理係藉由運用低能量光療以活化神經元內的粒線體,達到改善使用者視力的目的。 A multi-band eye device with red light and near-infrared light of the present invention A chemical device belongs to the technical field of using low-energy phototherapy, especially a retinal and optic nerve activation device composed of light-emitting diodes or lasers with red and near-infrared light bands. Energy light therapy activates the mitochondria in neurons to improve the user's vision.

本發明之一種具紅光及近紅外光多波段眼部活化裝置,主要係由一眼鏡形罩體所構成,並於罩體內設置紅光及近紅外光波段的發光二極體或雷射。 A multi-band eye activation device with red light and near-infrared light of the present invention is mainly composed of a spectacle-shaped cover, and a light-emitting diode or laser with red and near-infrared light bands is arranged in the cover.

本發明具紅光及近紅外光多波段眼部活化裝置及其操作方法,透過前述的設計,利用紅光及近紅外光可穿透眼角膜及水晶體,被視網膜及視神經元吸收的特性,進而產生活化神經元內的粒腺體的效果,藉以改善視網膜及視神經病變患者的視力。 The present invention has a red light and near-infrared light multi-band eye activation device and its operation method. Through the above-mentioned design, the red light and near-infrared light can penetrate the cornea and lens of the eye, and are absorbed by the retina and optic neurons. Produces the effect of activating the granulosa glands in neurons, thereby improving the vision of patients with retinal and optic neuropathy.

100:紅光及近紅外光多波段眼部活化裝置 100: Multi-band eye activation device for red and near-infrared light

110:罩體 110: cover body

120:紅光波段發光二極體或雷射 120: red light-emitting diode or laser

130:近紅外光波段發光二極體或雷射 130: Near-infrared light-emitting diodes or lasers

200:紅光多波段眼部活化裝置 200: Red light multi-band eye activation device

210:罩體 210: cover body

220:紅光波段發光二極體或雷射 220: red light-emitting diode or laser

230:近紅外光波段發光二極體或雷射 230: Near-infrared light-emitting diodes or lasers

300:紅光多波段眼部活化裝置 300: Red light multi-band eye activation device

310:罩體 310: cover body

320:紅光波段發光二極體或雷射 320: red light-emitting diode or laser

330:近紅外光波段發光二極體或雷射 330: Near-infrared light-emitting diodes or lasers

340:眼鏡 340: glasses

有關本發明之前述及其它許多優點,於以下配合參考圖示之一個較佳實施例的詳細說明中,將可更清楚呈現,其中如下: The foregoing and many other advantages of the present invention will be more clearly presented in the following detailed description of a preferred embodiment with reference to the accompanying drawings, among which are as follows:

第1圖顯示本發明之一種具紅光及近紅外光多波段眼部活化裝置; Figure 1 shows a multi-band eye activation device with red light and near-infrared light according to the present invention;

第2圖顯示本發明之一種具紅光及近紅外光多波段眼部活化裝置;以及 FIG. 2 shows a multi-band eye activation device with red light and near-infrared light according to the present invention; and

第3圖顯示本發明之一種具紅光及近紅外光多波段眼部活 化裝置。 Fig. 3 shows a multi-band eye device with red light and near-infrared light of the present invention chemical device.

以下請參照所附圖式說明與敘述,以對本發明之實施形態據以描述。圖式中,相同之元件符號表示相同之元件,且為求清楚說明,元件之大小或厚度可能誇大顯示。 Please refer to the accompanying drawings for description and description below to describe the embodiments of the present invention. In the drawings, the same reference numerals denote the same elements, and the size or thickness of the elements may be exaggerated for clarity.

本發明係一種具紅光及近紅外光多波段眼部活化裝置100,請參考第1圖所示,該眼睛活化裝置100主要係由一罩體110所構成,罩體110近似於眼鏡的形狀,而該罩體110內設有紅光波段發光二極體或雷射120,或者近紅外光波段發光二極體或雷射130以供產生光源,本裝置100可對使用者之眼睛進行照射。再請參考本發明第1圖之詳細構成,該罩體110可配合欲照射部之形狀進行設計,而本發明以人體臉型搭配眼睛部的位置為主要實施例,可以增加每個位置照射的均勻度。 The present invention is a multi-band eye activation device 100 with red light and near-infrared light. Please refer to FIG. 1. The eye activation device 100 is mainly composed of a cover 110, and the cover 110 is similar to the shape of glasses , and the cover body 110 is provided with a red light-band light-emitting diode or a laser 120, or a near-infrared light-band light-emitting diode or a laser 130 for generating a light source, and the device 100 can illuminate the eyes of the user . Please refer to the detailed structure of FIG. 1 of the present invention, the cover body 110 can be designed according to the shape of the part to be irradiated, and the present invention takes the face shape of the human body and the position of the eyes as the main embodiment, which can increase the uniformity of irradiation at each position. Spend.

仍如第1圖所示,於本發明中,紅光波段發光二極體或雷射120,以及近紅外光波段發光二極體或雷射130係以環型環繞分布於罩體110的排列方式,其中該罩體近似於一眼鏡形狀,該罩體具有可獨立使用的功能。而該紅光波段發光二極體或雷射120的波長約在620奈米(nm)至750奈米,且近紅外波段發光二極體或雷射130之光源則係因照射作用於視網膜及視神經,可刺激細胞內粒腺體,用以增進眼睛的活化。而設於罩體上的近紅外光波段發光二極體或雷射的波長約在750 奈米至2500奈米,同樣因照射作用於視網膜及視神經,可刺激細胞內粒腺體,以增進眼睛的活化。 Still as shown in FIG. 1 , in the present invention, the red light-band light-emitting diodes or lasers 120 and the near-infrared light-band light-emitting diodes or lasers 130 are arranged around the cover body 110 in a ring shape. method, wherein the cover body is similar to the shape of a pair of glasses, and the cover body has a function that can be used independently. The wavelength of the red-band light-emitting diode or the laser 120 is about 620 nanometers (nm) to 750 nanometers, and the light source of the near-infrared-band light-emitting diode or the laser 130 acts on the retina and Optic nerve, which stimulates intracellular granulosa glands to increase the activation of the eye. The wavelength of the near-infrared light-emitting diode or laser disposed on the cover is about 750 From nanometers to 2500 nanometers, the irradiation also acts on the retina and optic nerve, which can stimulate the intracellular granulocytes to enhance the activation of the eye.

參考如第2圖所示之本發明一種具紅光及近紅外光多波段眼部活化裝置200,該眼睛活化裝置200主要係由一罩體210所構成,罩體210近似於眼鏡的形狀,該罩體內設有紅光波段發光二極體或雷射220,或者近紅外光波段發光二極體或雷射230以供產生光源,可對使用者之眼睛進行照射。 Referring to a multi-band eye activation device 200 with red light and near-infrared light of the present invention as shown in FIG. 2, the eye activation device 200 is mainly composed of a cover 210, and the cover 210 is similar to the shape of glasses, The cover is provided with a red light-band light-emitting diode or laser 220, or a near-infrared light-band light-emitting diode or laser 230 for generating a light source, which can illuminate the user's eyes.

參考如第2圖所示,於本發明中,紅光波段發光二極體或雷射220,以及近紅外光波段發光二極體或雷射230係採以直列排列分布於罩體210的排列方式。 Referring to FIG. 2 , in the present invention, the red light-band light-emitting diodes or lasers 220 and the near-infrared light-band light-emitting diodes or lasers 230 are arranged in an in-line arrangement on the cover body 210 Way.

再請參考本發明第2圖之詳細構成,該罩體210可配合欲照射部之形狀設計,而本發明以人體臉型搭配眼睛部的位置為主要實施例,可以增加每個位置照射的均勻度。 Please refer to the detailed structure of FIG. 2 of the present invention. The cover body 210 can be designed according to the shape of the part to be irradiated. The main embodiment of the present invention is that the face shape of the human body matches the position of the eyes, which can increase the uniformity of irradiation at each position. .

如第3圖所示所示之本發明一種具紅光及近紅外光多波段眼部活化裝置300,該眼睛活化裝置300之一罩體310具有附加於一般眼鏡340的功能,而該罩體310內設有紅光波段發光二極體或雷射320,或者近紅外光波段發光二極體或雷射330以供產生光源,可對使用者之眼睛進行照射,以方便原有配戴眼鏡之使用者。 As shown in FIG. 3, a multi-band eye activating device 300 with red light and near-infrared light of the present invention is shown. A cover 310 of the eye activating device 300 has the function of being added to ordinary glasses 340, and the cover 310 is equipped with a red light-band light-emitting diode or laser 320, or a near-infrared light-band light-emitting diode or laser 330 to generate a light source, which can illuminate the user's eyes to facilitate the original wearing of glasses of users.

此外,於前述實施例中,該紅光波段發光二極體或雷射與該近紅外光波段發光二極體或雷射可連接發光二極體驅動電路(未顯示於圖式中),且該發光二極體驅動電路並連 接有操作介面與電源供應器。而其中電源供應器可源自於交流電或直流電,藉以利用操作介面調整,並透過控制電路板操控紅光波段發光二極體或雷射,以及近紅外光波段發光二極體或雷射的照射時間,波長及發光強度,藉以調整罩體的紅光波段發光二極體或雷射,以及近紅外光波段發光二極體或雷射的發光強度。且其中操作介面可調整本發明一種具紅光及近紅外光多波段眼部活化裝置100、200、300具有第一種僅發出紅光的功能,或是具有第二種僅發出近紅外光的功能,或是具有第三種發出紅光以及近紅外光的功能。 In addition, in the foregoing embodiment, the red light-band light-emitting diode or laser and the near-infrared light-band light-emitting diode or laser can be connected to a light-emitting diode driving circuit (not shown in the drawings), and The LED driver circuit is connected in parallel An operation interface and a power supply are connected. The power supply can be derived from alternating current or direct current, which can be adjusted using the operation interface, and the light-emitting diodes or lasers in the red band and the light-emitting diodes or lasers in the near-infrared band can be controlled through the control circuit board. Time, wavelength and luminous intensity, so as to adjust the luminous intensity of the red light-band light-emitting diode or laser and the near-infrared light-band light-emitting diode or laser of the cover body. And wherein the operation interface can adjust the multi-band eye activation device 100, 200, 300 with red light and near-infrared light of the present invention to have the first function of only emitting red light, or the second function of only emitting near-infrared light. function, or a third function that emits red and near-infrared light.

而前述有關的發光二極體驅動電路,其中該發光二極體驅動電路的晶片類型可分為恆壓式驅動晶片,恆流式驅動晶片以及脈衝式驅動晶片,常見的是恆壓式驅動晶片的DC/DC升壓晶片,而目前脈衝式驅動晶片則是以高頻率的脈衝發生器輸出,得以接口向發光二極體燈提供電源驅動。 As for the above-mentioned related LED driver circuit, the chip types of the LED driver circuit can be divided into constant voltage driver chip, constant current driver chip and pulse driver chip, the common one is constant voltage driver chip The DC/DC booster chip of the present invention, and the current pulse drive chip is output by a high-frequency pulse generator, which can provide power drive to the light-emitting diode lamp through the interface.

本發明之一種具紅光及近紅外光多波段眼部活化裝置100、200、300的操作方法,其第一種操作方法,係使得前述活化裝置100、200、300發出紅光,或是第二種操作方法,係使得該活化裝置100、200、300發出近紅外光,或是第三種操作方法,使得該活化裝置100、200、300發出紅光與近紅外光。 An operation method of the multi-band eye activation device 100, 200, 300 with red light and near-infrared light of the present invention, the first operation method is to make the aforementioned activation device 100, 200, 300 emit red light, or the first operation method The second operation method is to make the activation device 100, 200, 300 emit near-infrared light, or the third operation method is to make the activation device 100, 200, 300 emit red light and near-infrared light.

本發明實施例可使得人體眼睛內不同深度的微血管及細胞可進行照射吸收,使其得以吸收不同波長的光能, 讓眼睛組織具有吸收光能轉化成熱能的溫熱效果(約35℃至45℃之間),避免因溫度過低無法產生效果,或者因溫度過高而傷及眼睛組織。 The embodiments of the present invention can enable microvessels and cells of different depths in the human eye to be irradiated and absorbed, so that they can absorb light energy of different wavelengths. Let the eye tissue have a warming effect of absorbing light energy and converting it into heat energy (between about 35°C and 45°C), to avoid the effect of being too low to produce effects, or to damage the eye tissue due to too high temperature.

本發明於實際使用時,使用者可依欲治療的項目,選用適當的發光二極體組或雷射,使用者可於罩體內組裝紅光波段發光二極體或雷射,以及近紅外光波段發光二極體或雷射,並利用操作介面事先調節波長,時間及照射強度,接著將罩體罩設於使用者的臉部,於啟動紅光波段發光二極體或雷射,以及近紅外光波段發光二極體或雷射後,利用紅光波段發光二極體或雷射所發出的紅光及近紅外光波段發光二極體或雷射所發出的紅光,同步對使用者的眼睛以相對應方式進行照射,藉以利用光源照射眼睛後,所吸收的光能產生溫熱效應,以及光化學反應,使得眼睛產生活化及增生的效果,進而強化眼睛及視神經細胞。 When the present invention is actually used, the user can select an appropriate light-emitting diode group or laser according to the item to be treated, and the user can assemble the red-band light-emitting diode or laser and the near-infrared light in the cover. Band light-emitting diodes or lasers, and use the operation interface to adjust the wavelength, time and irradiation intensity in advance, and then cover the cover on the user's face, activate the red-band light-emitting diodes or lasers, and close the After the infrared light-emitting diode or laser, the red light emitted by the red light-emitting diode or laser and the red light emitted by the near-infrared light-emitting diode or laser are used to synchronize the user. The eyes are irradiated in a corresponding way, so that after using the light source to illuminate the eyes, the absorbed light energy produces a warming effect and a photochemical reaction, which makes the eyes activate and proliferate, thereby strengthening the eyes and optic nerve cells.

本發明之具紅光多波段眼部活化裝置及其操作方法,係運用原理臉係利用發光二極體或雷射具有不同波長之光質應用性,穩定性與效率,且由於發光二極體或雷射具有高光電轉換效率,達到省電效用,且因所產生的紅光及近紅外光可穿透眼角膜及水晶體,被視網膜及視神經元吸收的特性,進而產生活化神經元內的粒腺體的效果,藉以改善視網膜及視神經病變患者的視力。 The multi-band eye activation device with red light and its operation method of the present invention use the principle of using light-emitting diodes or lasers to have different wavelengths of light quality, applicability, stability and efficiency. Or the laser has a high photoelectric conversion efficiency, which can save power, and because the generated red light and near-infrared light can penetrate the cornea and lens, and be absorbed by the retina and optic neuron, and then generate granules in the activated neuron. Glands to improve vision in patients with retinal and optic neuropathy.

更且,由於本發明的結構簡易,同時其光源為一 般市面上之發光二極體或雷射,因此可供一般使用者於家中自由運用,並可配合使用者的時間及需求,具有增進經濟效益及提高使用便利性的功效。 Moreover, because the structure of the present invention is simple, and the light source is a The light-emitting diodes or lasers in the general market can be freely used by ordinary users at home, and can meet the user's time and needs, which has the effect of increasing economic efficiency and improving convenience of use.

以上所述僅為本發明之較佳實施例而已,並非用以限定本發明之申請專利範圍;凡其它未脫離本發明所揭示之精神下所完成之等效改變或修飾,均應包含在下述之申請專利範圍內。 The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the scope of the patent application of the present invention; all other equivalent changes or modifications accomplished without departing from the spirit disclosed in the present invention shall be included in the following within the scope of the patent application.

100:具紅光及近紅外光多波段眼部活化裝置 100: Multi-band eye activation device with red light and near-infrared light

110:罩體 110: cover body

120:紅光波段發光二極體或雷射 120: red light-emitting diode or laser

130:近紅外光波段發光二極體或雷射 130: Near-infrared light-emitting diodes or lasers

Claims (9)

一種紅光及近紅外光多波段眼部活化裝置,包含: A red light and near-infrared light multi-band eye activation device, comprising: 一罩體,其中該罩體近似於一眼鏡形狀,具有一可獨立使用的功能; a cover body, wherein the cover body is similar to the shape of a pair of glasses and has a function that can be used independently; 一紅光波段發光源; A luminous source in the red band; 一近紅外光波段發光源;以及 a near-infrared light-emitting source; and 一驅動電路,該驅動電路連接一操作介面與一電源供應器。 a driving circuit, the driving circuit is connected with an operation interface and a power supply. 如申請專利範圍第1項所述之裝置,其中該罩體更具有附加於一使用者之眼鏡的功能。 The device of claim 1, wherein the cover further has the function of being attached to a user's glasses. 如申請專利範圍第1項所述之裝置,其中該紅光波段發光源的波長約在620奈米至750奈米。 The device according to item 1 of the claimed scope, wherein the wavelength of the red light-band light source is about 620 nm to 750 nm. 如申請專利範圍第1項所述之裝置,其中該紅光波段發光源係由發光二極體以及半導體雷射二極體群組中所選出。 The device of claim 1, wherein the red light-band light-emitting source is selected from the group of light-emitting diodes and semiconductor laser diodes. 如申請專利範圍第1項所述之裝置,其中該近紅外光波段發光源的波長約在750奈米至2500奈米。 The device of claim 1, wherein the wavelength of the near-infrared light-emitting source is about 750 nm to 2500 nm. 如申請專利範圍第1項所述之裝置,其中該近紅外光波段發光源係由發光二極體以及半導體雷射二極體群組中所選出。 The device of claim 1, wherein the near-infrared light-emitting source is selected from the group consisting of light-emitting diodes and semiconductor laser diodes. 如申請專利範圍第1項所述之裝置,其中該紅光波段發光源以及該近紅外光波段發光源係以一直列排列分布於該罩體的排列方式。 The device according to claim 1, wherein the red light-band light-emitting source and the near-infrared light-band light source are distributed in the cover body in a line arrangement. 如申請專利範圍第1項所述之裝置,其中該紅光波段發光源以及該近紅外光波段發光源係以一環型環繞排列分布於該罩體的排列方式。 The device according to claim 1, wherein the red light-band light-emitting source and the near-infrared light-band light source are distributed in a ring-shaped surrounding arrangement on the cover body. 一種如申請專利範圍第1項所述之裝置的控制方法,係使得該裝置發出一紅光,或是係使得該活化裝置發出一近紅外光,或是係使得該活化裝置發出一紅光以及一近紅外光。 A control method of the device as described in item 1 of the scope of application, which makes the device emit a red light, or makes the activation device emit a near-infrared light, or makes the activation device emit a red light, and A near-infrared light.
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