TW202130340A - Pressure release pad for preventing pressure ulcer capable of effectively preventing formation of pressure ulcer and helping healing existed pressure ulcer wound - Google Patents

Pressure release pad for preventing pressure ulcer capable of effectively preventing formation of pressure ulcer and helping healing existed pressure ulcer wound Download PDF

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TW202130340A
TW202130340A TW109112949A TW109112949A TW202130340A TW 202130340 A TW202130340 A TW 202130340A TW 109112949 A TW109112949 A TW 109112949A TW 109112949 A TW109112949 A TW 109112949A TW 202130340 A TW202130340 A TW 202130340A
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pressure
preventing
adhesive
elastic layer
pad
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TW109112949A
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TWI744865B (en
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辜雅文
王仁賢
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中鎮醫療產品科技股份有限公司
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Priority claimed from TW109201392U external-priority patent/TWM593851U/en
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    • C—CHEMISTRY; METALLURGY
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    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J7/00—Adhesives in the form of films or foils
    • C09J7/20—Adhesives in the form of films or foils characterised by their carriers
    • C09J7/29—Laminated material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
    • A61G7/00—Beds specially adapted for nursing; Devices for lifting patients or disabled persons
    • A61G7/05—Parts, details or accessories of beds
    • A61G7/057—Arrangements for preventing bed-sores or for supporting patients with burns, e.g. mattresses specially adapted therefor
    • A61G7/05738—Arrangements for preventing bed-sores or for supporting patients with burns, e.g. mattresses specially adapted therefor with fluid-like particles, e.g. sand, mud, seeds, gel, beads
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    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
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    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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    • C08G18/30—Low-molecular-weight compounds
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
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    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4829—Polyethers containing at least three hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4833—Polyethers containing oxyethylene units
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/50—Polyethers having heteroatoms other than oxygen
    • C08G18/5021—Polyethers having heteroatoms other than oxygen having nitrogen
    • C08G18/5024—Polyethers having heteroatoms other than oxygen having nitrogen containing primary and/or secondary amino groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/76—Polyisocyanates or polyisothiocyanates cyclic aromatic
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
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    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J175/00—Adhesives based on polyureas or polyurethanes; Adhesives based on derivatives of such polymers
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    • C09J175/08—Polyurethanes from polyethers
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    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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    • C09J7/30—Adhesives in the form of films or foils characterised by the adhesive composition
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    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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    • C09J2400/00—Presence of inorganic and organic materials
    • C09J2400/20—Presence of organic materials
    • C09J2400/24—Presence of a foam
    • C09J2400/243—Presence of a foam in the substrate
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    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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    • C09J2475/00—Presence of polyurethane
    • C09J2475/006—Presence of polyurethane in the substrate

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  • Chemical & Material Sciences (AREA)
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Abstract

A pressure release pad for preventing pressure ulcer, which includes an elastic layer, an adhesive carrying film carrying adhesive, a hydrogel layer, and a release film. The elastic layer is made of a slow resilient material. The adhesive carring film is attached to one side of the elastic layer. The hydrogel layer is attached to the side of the adhesive carrying film opposite to the elastic layer. The release film covers one side of the hydrogel layer opposite to the adhesive carrying film. The pressure release pad for preventing pressure ulcer according to the present invention may effectively prevent the formation of pressure ulcer and help healing the existed pressure ulcer wound.

Description

預防壓瘡用的減壓墊Pressure relief pad for preventing pressure sores

本發明是有關於一種減壓墊，特別是指一種預防壓瘡用的減壓墊。The present invention relates to a pressure-reducing pad, in particular to a pressure-reducing pad for preventing pressure sores.

壓瘡(Pressure ulcer)又稱為褥瘡(bedsore)，是由於皮膚或其下層組織受到長時間壓迫所導致的局部細胞缺氧壞死，好發於長期肢體不活動的個體或是長期臥床的病人。Pressure ulcer, also known as bedsore, is the hypoxic necrosis of local cells caused by prolonged compression of the skin or its underlying tissues. It is more common in individuals with long-term limb inactivity or patients who have been bedridden for a long time.

現有預防壓瘡的方式大多是透過替個體更換姿勢(翻身擺位)，並合併使用軟墊、氣墊或水墊等減壓輔具，以減少組織受壓的情況。Most of the existing methods to prevent pressure ulcers are by changing the posture of the individual (turning over and positioning), and combining the use of decompression aids such as soft cushions, air cushions, or water cushions to reduce tissue pressure.

TW I586345提供一種預防壓瘡之減壓墊，其包含多孔泡棉減壓層、與皮膚接觸的親水性薄膜層及含有預設圖案的離型紙，可有效減低皮膚受到的壓力。然而，其薄膜層只能降低泡棉對於皮膚或傷口的摩擦力，對於壓瘡的傷口癒合沒有助益。TW I586345 provides a pressure-reducing pad for preventing pressure ulcers, which includes a porous foam pressure-reducing layer, a hydrophilic film layer in contact with the skin, and a release paper with a preset pattern, which can effectively reduce the pressure on the skin. However, the film layer can only reduce the friction of the foam on the skin or wound, and is not helpful for the wound healing of pressure sores.

因此，本發明之目的，即在提供一種預防壓瘡用的減壓墊，可以克服上述先前技術的缺點。Therefore, the purpose of the present invention is to provide a pressure-reducing pad for preventing pressure sores, which can overcome the above-mentioned shortcomings of the prior art.

於是，本發明預防壓瘡用的減壓墊包含一彈性層、一承載有接著劑的載膠膜、一水膠層(hydrogel layer)及一離型膜。該彈性層由一慢回彈材料所製成。該載膠膜附著於該彈性層的一側。該水膠層附著於該載膠膜相反於該彈性層的一側。該離型膜覆蓋於該水膠層相反於該載膠膜的一側。Therefore, the pressure-reducing pad for preventing pressure ulcers of the present invention includes an elastic layer, a carrier film carrying an adhesive, a hydrogel layer, and a release film. The elastic layer is made of a slow rebound material. The adhesive film is attached to one side of the elastic layer. The water adhesive layer is attached to the side of the adhesive film opposite to the elastic layer. The release film covers the side of the water glue layer opposite to the glue-carrying film.

本發明之功效在於：該預防壓瘡用的減壓墊可有效預防壓瘡生成，且能有助於既有的壓瘡傷口癒合。The effect of the present invention is that the pressure-reducing pad for preventing pressure ulcers can effectively prevent the formation of pressure ulcers and can help the healing of existing pressure ulcers.

以下將就本發明內容進行詳細說明：The content of the present invention will be described in detail below:

較佳地，該水膠層的材料是由一含疏水性基團的多元醇與一含親水性基團的二異氰酸酯進行預聚合並經交聯及封端而得。更佳地，該疏水性基團是選自於聚丙二醇(PPG)、聚四氫呋喃(PTMG)或其組合，該親水性基團為聚乙二醇(PEG)，該多元醇為六元醇。Preferably, the material of the hydrogel layer is obtained by pre-polymerizing a polyol containing a hydrophobic group and a diisocyanate containing a hydrophilic group, crosslinking and blocking. More preferably, the hydrophobic group is selected from polypropylene glycol (PPG), polytetrahydrofuran (PTMG) or a combination thereof, the hydrophilic group is polyethylene glycol (PEG), and the polyol is a hexahydric alcohol.

較佳地，該水膠層的厚度範圍為0.01~1.00 cm。更佳地，該水膠層的厚度範圍為0.20~0.50 cm。Preferably, the thickness of the hydrogel layer ranges from 0.01 cm to 1.00 cm. More preferably, the thickness of the hydrogel layer ranges from 0.20 to 0.50 cm.

較佳地，該載膠膜的材料是選自於聚乙烯、聚丙烯、聚氨酯、聚醯胺或其組合。在本發明的具體實施例中，該載膠膜的材料是聚氨酯。Preferably, the material of the adhesive film is selected from polyethylene, polypropylene, polyurethane, polyamide or a combination thereof. In a specific embodiment of the present invention, the material of the adhesive film is polyurethane.

較佳地，該載膠膜是選自於吹製而成的聚合物薄膜或高壓黏合而成的不織布。Preferably, the adhesive film is selected from blown polymer films or high-pressure bonded non-woven fabrics.

較佳地，該接著劑是選自於熱熔膠、壓克力膠或聚矽氧(silicone)。在本發明的具體實施例中，該接著劑是熱熔膠。Preferably, the adhesive is selected from hot melt adhesive, acrylic adhesive or silicone. In a specific embodiment of the present invention, the adhesive is a hot melt adhesive.

在本發明的具體實施例中，該彈性層是可撓性多孔狀聚氨酯泡棉(flexible cellular polyurethane foam sponge)。In a specific embodiment of the present invention, the elastic layer is flexible cellular polyurethane foam sponge.

較佳地，該彈性層的材料是由一含疏水性基團的多元醇與一含疏水性基團的二異氰酸酯預聚物在聚矽氧、胺基矽烷類化合物及發泡劑的存在下進行聚合及發泡而得。更佳地，該二異氰酸酯預聚物中的疏水性基團的重量平均分子量範圍為1500~6000 g/mol，該多元醇中的疏水性基團的重量平均分子量範圍為200~1000 g/mol，該聚矽氧的重量平均分子量範圍為1000~20000 g/mol。在本發明的具體實施例中，該二異氰酸酯預聚物中的疏水性基團的重量平均分子量範圍為2000~3000 g/mol。更佳地，該胺基矽烷類化合物是選自於(3-胺基丙基)三乙氧基矽烷(APTES)、(3-胺基丙基)三甲氧基矽烷(APTMS)、(3-胺基丙基)二乙氧基甲基矽烷(APDEMS)或其組合。更佳地，該疏水性基團是選自於聚丙二醇、聚四氫呋喃或其組合。在本發明的具體實施例中，該聚矽氧是聚二甲基矽氧烷(PDMS)，該胺基矽烷類化合物是(3-胺基丙基)三乙氧基矽烷(APTES)，該發泡劑是水。Preferably, the material of the elastic layer is composed of a hydrophobic group-containing polyol and a hydrophobic group-containing diisocyanate prepolymer in the presence of polysiloxane, aminosilane compound and blowing agent It is obtained by polymerization and foaming. More preferably, the weight average molecular weight of the hydrophobic groups in the diisocyanate prepolymer ranges from 1500 to 6000 g/mol, and the weight average molecular weight of the hydrophobic groups in the polyol ranges from 200 to 1000 g/mol , The weight average molecular weight of the polysiloxane ranges from 1,000 to 20,000 g/mol. In a specific embodiment of the present invention, the weight average molecular weight of the hydrophobic group in the diisocyanate prepolymer ranges from 2000 to 3000 g/mol. More preferably, the aminosilane compound is selected from (3-aminopropyl)triethoxysilane (APTES), (3-aminopropyl)trimethoxysilane (APTMS), (3-aminopropyl)triethoxysilane (APTES), (3-aminopropyl)trimethoxysilane (APTMS), Aminopropyl) diethoxymethyl silane (APDEMS) or a combination thereof. More preferably, the hydrophobic group is selected from polypropylene glycol, polytetrahydrofuran or a combination thereof. In a specific embodiment of the present invention, the polysiloxane is polydimethylsiloxane (PDMS), the aminosilane compound is (3-aminopropyl)triethoxysilane (APTES), and the The blowing agent is water.

較佳地，該彈性層的厚度範圍為1~10 cm。更佳地，該彈性層的厚度範圍為2.5~3.0 cm。Preferably, the thickness of the elastic layer ranges from 1 to 10 cm. More preferably, the thickness of the elastic layer ranges from 2.5 cm to 3.0 cm.

較佳地，依據ASTM D3574-17測試該減壓墊的落球回彈率小於30%。更佳地，依據ASTM D3574-17測試該減壓墊的落球回彈率小於10%。Preferably, according to ASTM D3574-17, the falling ball rebound rate of the pressure reducing mat is less than 30%. More preferably, according to ASTM D3574-17, the ball rebound rate of the decompression mat is less than 10%.

在本發明被詳細描述之前，應當注意在以下的說明內容中，類似的元件是以相同的編號來表示。Before the present invention is described in detail, it should be noted that in the following description, similar elements are denoted by the same numbers.

本發明將就以下實施例來作進一步說明，但應瞭解的是，該實施例僅為例示說明之用，而不應被解釋為本發明實施之限制。The present invention will be further described in the following embodiments, but it should be understood that the embodiments are only for illustrative purposes and should not be construed as limitations on the implementation of the present invention.

參閱圖1，本發明預防壓瘡用的減壓墊1之一實施例包含一彈性層11、一承載有接著劑的載膠膜12、一水膠層13及一離型膜14。Referring to FIG. 1, an embodiment of the pressure-reducing pad 1 for preventing pressure ulcers of the present invention includes an elastic layer 11, a carrier film 12 carrying an adhesive, a hydrogel layer 13 and a release film 14.

該彈性層11由一慢回彈材料所製成。在本實施例中，該彈性層11是可撓性多孔狀聚氨酯泡棉，其尺寸為長20 cm、寬15 cm、厚2.5 cm的長方體。The elastic layer 11 is made of a slow rebound material. In this embodiment, the elastic layer 11 is a flexible porous polyurethane foam, and its size is a rectangular parallelepiped with a length of 20 cm, a width of 15 cm, and a thickness of 2.5 cm.

本實施例的彈性層11的材料是由以下步驟所製備：The material of the elastic layer 11 in this embodiment is prepared by the following steps:

步驟(a)：在密閉的氮氣環境中，將2,4-甲苯二異氰酸酯(2,4-TDI)與聚丙二醇二元醇(PPG 3000 diol)以莫耳比2：1的比例混合，在80℃中攪拌反應90 min，利用FT-IR監測波數在2270 cm-1 處之NCO特徵峰的存在，以得到一每分子含有二個異氰酸酯基團的預聚物。Step (a): In a closed nitrogen environment, mix 2,4-toluene diisocyanate (2,4-TDI) and polypropylene glycol diol (PPG 3000 diol) at a molar ratio of 2:1. The reaction was stirred at 80°C for 90 minutes, and FT-IR was used to monitor the presence of the NCO characteristic peak at 2270 cm -1 to obtain a prepolymer containing two isocyanate groups per molecule.

步驟(b)：在密閉的氮氣環境中，將該預聚物、聚丙二醇三元醇(PPG 400 triol)、水、聚二甲基矽氧烷(PDMS，重量平均分子量為1000~3000)、(3-胺基丙基)三乙氧基矽烷(APTES)以莫耳比1：1：0.4：0.3：0.3的比例混合，並添加0.1 wt%辛酸亞錫(T9) (以上述所以成分之總重為100 wt%)作為催化劑，在20℃中攪拌反應5 min，再於30~40℃中靜置24 h使其發泡完全，得到一可撓性多孔狀聚氨酯泡棉。Step (b): In a closed nitrogen environment, the prepolymer, polypropylene glycol triol (PPG 400 triol), water, polydimethylsiloxane (PDMS, weight average molecular weight is 1000~3000), (3-Aminopropyl) triethoxysilane (APTES) was mixed in a molar ratio of 1:1:0.4:0.3:0.3, and 0.1 wt% stannous octoate (T9) was added (based on all the above ingredients). The total weight is 100 wt%) as a catalyst, the reaction is stirred at 20°C for 5 min, and then allowed to stand at 30-40°C for 24 hours to completely foam, and a flexible porous polyurethane foam is obtained.

該載膠膜12附著於該彈性層11的一側。在本實施例中，該載膠膜12是吹製而成的聚氨酯薄膜，其厚度約為0.7 mm；該接著劑是聚異丁烯橡膠型熱熔膠。The adhesive film 12 is attached to one side of the elastic layer 11. In this embodiment, the adhesive film 12 is a blown polyurethane film with a thickness of about 0.7 mm; the adhesive is a polyisobutylene rubber hot melt adhesive.

該水膠層13附著於該載膠膜12相反於該彈性層11的一側。在本實施例中，該水膠層13的材料是由一含聚丙二醇的六元醇與一含聚乙二醇的二異氰酸酯進行預聚合並經交聯及封端而得。The water adhesive layer 13 is attached to the side of the adhesive film 12 opposite to the elastic layer 11. In this embodiment, the material of the hydrogel layer 13 is obtained by prepolymerizing a hexahydric alcohol containing polypropylene glycol and a diisocyanate containing polyethylene glycol, crosslinking and blocking.

本實施例的水膠層13的材料是由以下步驟所製備：The material of the water glue layer 13 in this embodiment is prepared by the following steps:

步驟(a1)：在密閉的氮氣環境中，將1,1,1-三羥甲基丙烷(TMP)與六亞甲基二異氰酸酯(HDI)以莫耳比1：3的比例混合，並添加0.05 wt%三乙烯二胺(triethylenediamine, TEDA) (以TMP及HDI之總重為100 wt%)作為催化劑，在80℃中攪拌反應90 min，利用FT-IR監測波數在2270 cm-1 處之NCO特徵峰的存在，以得到三異氰酸酯中間物。Step (a1): In a closed nitrogen environment, mix 1,1,1-trimethylolpropane (TMP) and hexamethylene diisocyanate (HDI) at a molar ratio of 1:3, and add 0.05 wt% triethylenediamine (TEDA) (the total weight of TMP and HDI is 100 wt%) is used as a catalyst, the reaction is stirred at 80℃ for 90 min, and the wave number is monitored at 2270 cm -1 by FT-IR The existence of the characteristic peak of NCO in order to obtain the intermediate triisocyanate.

步驟(a2)：在密閉的氮氣環境中，將該三異氰酸酯中間物與聚丙二醇三元醇(PPG 4000 triol)以莫耳比1：3的比例混合，並添加0.05 wt% TEDA (以該三異氰酸酯及PPG triol之總重為100 wt%)作為催化劑，在80℃中攪拌反應90 min，利用FT-IR監測波數在2270 cm-1 處之NCO特徵峰的消失，以得到含聚丙二醇的疏水性六元醇。Step (a2): In a closed nitrogen environment, the intermediate triisocyanate and polypropylene glycol triol (PPG 4000 triol) are mixed at a molar ratio of 1:3, and 0.05 wt% TEDA (based on the three The total weight of isocyanate and PPG triol is 100 wt%) as a catalyst, and the reaction is stirred at 80°C for 90 min. The disappearance of the characteristic NCO peak at 2270 cm -1 is monitored by FT-IR to obtain polypropylene glycol-containing Hydrophobic hexahydric alcohol.

步驟(b)：在密閉的氮氣環境中，將聚乙二醇(PEG 1000 diol)與HDI以莫耳比1：2的比例混合，並添加0.05 wt% TEDA (以PEG diol及HDI之總重為100 wt%)作為催化劑，在80℃中攪拌反應90 min，利用FT-IR監測波數在2270 cm-1 處之NCO特徵峰的存在，以得到含聚乙二醇的親水性二異氰酸酯。Step (b): In a closed nitrogen environment, mix polyethylene glycol (PEG 1000 diol) and HDI at a molar ratio of 1:2, and add 0.05 wt% TEDA (based on the total weight of PEG diol and HDI) 100 wt%) as a catalyst, the reaction was stirred at 80°C for 90 min, and the presence of the NCO characteristic peak at 2270 cm -1 was monitored by FT-IR to obtain a hydrophilic diisocyanate containing polyethylene glycol.

步驟(c)：在密閉的氮氣環境中，將該疏水性六元醇與該親水性二異氰酸酯以莫耳比1：6的比例混合，在80℃中攪拌反應90 min，利用FT-IR監測波數在2270 cm-1 處之NCO特徵峰的存在，以得到一每分子含有六個異氰酸酯基團的第一預聚物。該第一預聚物的內部具疏水性而外部具親水性。Step (c): Mix the hydrophobic hexahydric alcohol and the hydrophilic diisocyanate at a molar ratio of 1:6 in a closed nitrogen environment, stir the reaction at 80°C for 90 min, and monitor by FT-IR The existence of the characteristic peak of NCO at the wave number of 2270 cm -1 to obtain a first prepolymer containing six isocyanate groups per molecule. The interior of the first prepolymer is hydrophobic and the exterior is hydrophilic.

步驟(d)：在密閉的氮氣環境中，在該第一預聚物中以莫耳比2：0.2的比例加入聚乙二醇二胺(PEG diamine 5000)作為交聯劑，在80℃中攪拌反應90 min，利用FT-IR監測波數在2270 cm-1 處之NCO特徵峰不再減弱，以交聯得到一含有3~6個異氰酸酯基團的第二預聚物。在本實施例中，該第二預聚物的重量平均分子量為52000 g/mol。Step (d): In a closed nitrogen environment, polyethylene glycol diamine (PEG diamine 5000) is added as a cross-linking agent at a molar ratio of 2:0.2 to the first prepolymer, and the temperature is at 80°C. The reaction was stirred for 90 min, and the NCO characteristic peak at 2270 cm -1 was monitored by FT-IR, and a second prepolymer containing 3-6 isocyanate groups was obtained by cross-linking. In this embodiment, the weight average molecular weight of the second prepolymer is 52000 g/mol.

步驟(e)：在密閉的氮氣環境中，在該第二預聚物中以莫耳比1：0.8的比例加入(3-胺基丙基)三乙氧基矽烷(APTES)，在80℃中攪拌反應90 min，使該第二預聚物封端，利用FT-IR監測波數在2270 cm-1 處之NCO特徵峰的消失，以得到本實施例的水膠層13的材料。Step (e): Add (3-aminopropyl)triethoxysilane (APTES) to the second prepolymer at a molar ratio of 1:0.8 in a closed nitrogen environment, at 80°C The reaction was stirred for 90 minutes to make the second prepolymer end-capped, and the disappearance of the NCO characteristic peak at 2270 cm −1 was monitored by FT-IR to obtain the material of the hydrogel layer 13 of this embodiment.

在本實施例中，該水膠層13的厚度約為0.25 cm。In this embodiment, the thickness of the hydrogel layer 13 is about 0.25 cm.

該離型膜14覆蓋於該水膠層13相反於該載膠膜12的一側。The release film 14 covers the side of the water adhesive layer 13 opposite to the adhesive film 12.

本實施例的減壓墊1是由以下步驟所製得：將該承載有接著劑的載膠膜12與該彈性層11黏合，再將該水膠層13的材料塗佈於該載膠膜12相反於該彈性層11的一側，以形成該水膠層13。最後在該水膠層13相反於該載膠膜12的一側上覆蓋該離型膜14，以避免該水膠層13在接觸皮膚之前受到汙染或降低附著性。The decompression pad 1 of this embodiment is made by the following steps: bonding the adhesive carrier film 12 with the adhesive to the elastic layer 11, and then coating the material of the water adhesive layer 13 on the adhesive film 12 is opposite to the side of the elastic layer 11 to form the hydrogel layer 13. Finally, the release film 14 is covered on the side of the hydrogel layer 13 opposite to the adhesive film 12 to prevent the hydrogel layer 13 from being polluted or reducing adhesion before it contacts the skin.

依據ASTM D3574-17測試本實施例的減壓墊1的落球回彈率約為3%。According to ASTM D3574-17, the ball rebound rate of the decompression mat 1 of this embodiment is about 3%.

參閱圖2，當使用者欲使用本實施例的減壓墊1時，可將該離型膜14從該水膠層13上撕除後，再將連同該載膠膜12及該彈性層11的水膠層13貼附於骶骨(sacrum)處的皮膚上，即可減輕該處皮膚坐臥時受到的壓力。Referring to FIG. 2, when the user wants to use the pressure-reducing pad 1 of this embodiment, the release film 14 can be removed from the water-adhesive layer 13, and then together with the adhesive film 12 and the elastic layer 11 The hydrogel layer 13 is attached to the skin of the sacrum, which can reduce the pressure on the skin when sitting or lying down.

綜上所述，本發明預防壓瘡用的減壓墊1藉由分別附著於該載膠膜12兩側的彈性層11及水膠層13，可有效預防壓瘡生成，且能有助於既有的壓瘡傷口癒合，故確實能達成本發明之目的。In summary, the pressure-reducing pad 1 for preventing pressure ulcers of the present invention can effectively prevent the formation of pressure ulcers by attaching the elastic layer 11 and the hydrogel layer 13 on both sides of the adhesive film 12 to effectively prevent pressure ulcers. The existing pressure sore wounds heal, so it can indeed achieve the purpose of the invention.

惟以上所述者，僅為本發明之實施例而已，當不能以此限定本發明實施之範圍，凡是依本發明申請專利範圍及專利說明書內容所作之簡單的等效變化與修飾，皆仍屬本發明專利涵蓋之範圍內。However, the above are only examples of the present invention. When the scope of implementation of the present invention cannot be limited by this, all simple equivalent changes and modifications made in accordance with the scope of the patent application of the present invention and the content of the patent specification still belong to This invention patent covers the scope.

1:減壓墊 11:彈性層 12:載膠膜 13:水膠層 14:離型膜1: Pressure relief pad 11: Elastic layer 12: Adhesive film 13: Water glue layer 14: Release film

本發明之其他的特徵及功效，將於參照圖式的實施方式中清楚地呈現，其中： ［圖1］是本發明預防壓瘡用的減壓墊的一實施例的結構示意圖； ［圖2］是一示意圖，說明該實施例於使用時的狀態。Other features and effects of the present invention will be clearly presented in the embodiments with reference to the drawings, in which: [Figure 1] is a schematic structural view of an embodiment of the pressure-reducing pad for preventing pressure sores of the present invention; [Figure 2] is a schematic diagram illustrating the state of the embodiment in use.

1:減壓墊1: Pressure relief pad

11:彈性層11: Elastic layer

12:載膠膜12: Adhesive film

13:水膠層13: Water glue layer

14:離型膜14: Release film

Claims (13)

一種預防壓瘡用的減壓墊，包含： 一彈性層，由一慢回彈材料所製成； 一承載有接著劑的載膠膜，附著於該彈性層的一側； 一水膠層，附著於該載膠膜相反於該彈性層的一側；及 一離型膜，覆蓋於該水膠層相反於該載膠膜的一側。A pressure-reducing pad for preventing pressure ulcers, including: An elastic layer, made of a slow rebound material; A carrier film carrying an adhesive, attached to one side of the elastic layer; A water glue layer attached to the side of the glue-carrying film opposite to the elastic layer; and A release film covering the side of the water glue layer opposite to the glue carrying film. 如請求項1所述的預防壓瘡用的減壓墊，其中，該水膠層的材料是由一含疏水性基團的多元醇與一含親水性基團的二異氰酸酯進行預聚合並經交聯及封端而得。The pressure-reducing pad for preventing pressure ulcers according to claim 1, wherein the material of the hydrogel layer is prepolymerized and prepolymerized by a polyol containing a hydrophobic group and a diisocyanate containing a hydrophilic group. It is obtained by cross-linking and end-blocking. 如請求項2所述的預防壓瘡用的減壓墊，其中，該疏水性基團是選自於聚丙二醇、聚四氫呋喃或其組合，該親水性基團為聚乙二醇，該多元醇為六元醇。The pressure-reducing pad for preventing pressure ulcers according to claim 2, wherein the hydrophobic group is selected from polypropylene glycol, polytetrahydrofuran or a combination thereof, the hydrophilic group is polyethylene glycol, and the polyol It is a hexavalent alcohol. 如請求項1所述的預防壓瘡用的減壓墊，其中，該水膠層的厚度範圍為0.01~1.00 cm。The pressure relief pad for preventing pressure ulcers according to claim 1, wherein the thickness of the hydrogel layer ranges from 0.01 cm to 1.00 cm. 如請求項1所述的預防壓瘡用的減壓墊，其中，該載膠膜的材料是選自於聚乙烯、聚丙烯、聚氨酯、聚醯胺或其組合。The pressure relief pad for preventing pressure sores according to claim 1, wherein the material of the adhesive film is selected from polyethylene, polypropylene, polyurethane, polyamide or a combination thereof. 如請求項1所述的預防壓瘡用的減壓墊，其中，該載膠膜是選自於吹製而成的聚合物薄膜或高壓黏合而成的不織布。The pressure-reducing pad for preventing pressure ulcers according to claim 1, wherein the adhesive film is selected from blown polymer films or high-pressure bonded non-woven fabrics. 如請求項1所述的預防壓瘡用的減壓墊，其中，該接著劑是選自於熱熔膠、壓克力膠或聚矽氧。The pressure-reducing pad for preventing pressure ulcers according to claim 1, wherein the adhesive is selected from hot melt adhesive, acrylic adhesive or silicone. 如請求項1所述的預防壓瘡用的減壓墊，其中，該彈性層是可撓性多孔狀聚氨酯泡棉。The pressure-reducing pad for preventing pressure ulcers according to claim 1, wherein the elastic layer is a flexible porous polyurethane foam. 如請求項1所述的預防壓瘡用的減壓墊，其中，該彈性層的材料是由一含疏水性基團的多元醇與一含疏水性基團的二異氰酸酯預聚物在聚矽氧、胺基矽烷類化合物及發泡劑的存在下進行聚合及發泡而得。The pressure-reducing pad for preventing pressure ulcers according to claim 1, wherein the material of the elastic layer is composed of a polyol containing a hydrophobic group and a diisocyanate prepolymer containing a hydrophobic group in a polysilicon It is obtained by polymerization and foaming in the presence of oxygen, aminosilane compounds and foaming agent. 如請求項9所述的預防壓瘡用的減壓墊，其中，該二異氰酸酯預聚物中的疏水性基團的重量平均分子量範圍為1500~6000 g/mol。The pressure-reducing pad for preventing pressure ulcers according to claim 9, wherein the weight average molecular weight of the hydrophobic group in the diisocyanate prepolymer is in the range of 1500 to 6000 g/mol. 如請求項9所述的預防壓瘡用的減壓墊，其中，該疏水性基團是選自於聚丙二醇、聚四氫呋喃或其組合。The pressure-reducing pad for preventing pressure ulcers according to claim 9, wherein the hydrophobic group is selected from polypropylene glycol, polytetrahydrofuran or a combination thereof. 如請求項1所述的預防壓瘡用的減壓墊，其中，該彈性層的厚度範圍為1~10 cm。The pressure relief pad for preventing pressure ulcers according to claim 1, wherein the thickness of the elastic layer ranges from 1 to 10 cm. 如請求項1所述的預防壓瘡用的減壓墊，其中，依據ASTM D3574-17測試該減壓墊的落球回彈率小於30%。The pressure-reducing mat for preventing pressure ulcers according to claim 1, wherein the ball rebound rate of the pressure-reducing mat tested according to ASTM D3574-17 is less than 30%.
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