TW202108561A - 用於治療痛風或高尿酸血症之化合物 - Google Patents

用於治療痛風或高尿酸血症之化合物 Download PDF

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Publication number
TW202108561A
TW202108561A TW109115899A TW109115899A TW202108561A TW 202108561 A TW202108561 A TW 202108561A TW 109115899 A TW109115899 A TW 109115899A TW 109115899 A TW109115899 A TW 109115899A TW 202108561 A TW202108561 A TW 202108561A
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TW
Taiwan
Prior art keywords
compound
effective amount
therapeutically effective
pharmaceutically acceptable
pharmaceutical composition
Prior art date
Application number
TW109115899A
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English (en)
Chinese (zh)
Inventor
順啟 顏
立天 葉
戎子 顏
贊聰 沈
Original Assignee
美商安索治療公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美商安索治療公司 filed Critical 美商安索治療公司
Publication of TW202108561A publication Critical patent/TW202108561A/zh

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
TW109115899A 2019-05-14 2020-05-13 用於治療痛風或高尿酸血症之化合物 TW202108561A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962847519P 2019-05-14 2019-05-14
US62/847,519 2019-05-14

Publications (1)

Publication Number Publication Date
TW202108561A true TW202108561A (zh) 2021-03-01

Family

ID=73288915

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109115899A TW202108561A (zh) 2019-05-14 2020-05-13 用於治療痛風或高尿酸血症之化合物

Country Status (14)

Country Link
US (1) US20220242841A1 (https=)
EP (1) EP3968989A4 (https=)
JP (1) JP7656548B2 (https=)
KR (1) KR20220016105A (https=)
CN (1) CN113874014A (https=)
AU (2) AU2020274165A1 (https=)
BR (1) BR112021022843A2 (https=)
CA (1) CA3140412A1 (https=)
IL (1) IL288034B1 (https=)
MA (1) MA55973A (https=)
MX (1) MX2021013980A (https=)
SG (1) SG11202112562XA (https=)
TW (1) TW202108561A (https=)
WO (1) WO2020232156A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202105743RA (en) 2018-12-06 2021-06-29 Arthrosi Therapeutics Inc Methods for treating or preventing gout or hyperuricemia
KR102946486B1 (ko) 2018-12-06 2026-03-31 아쓰로시 테라퓨틱스, 인크. 통풍 또는 고뇨산혈증의 치료 또는 예방을 위한 화합물의 결정형
KR20230024354A (ko) * 2020-06-10 2023-02-20 아쓰로시 테라퓨틱스, 인크. 만성 신장 질환을 치료 또는 예방하는 방법
WO2023058975A1 (ko) * 2021-10-07 2023-04-13 (주)이노보테라퓨틱스 벤조퓨라닐 히드록시페닐 메타논 유도체를 포함하는 hsp47 억제용 약학 조성물
TW202330485A (zh) * 2021-12-02 2023-08-01 美商安索治療公司 用於治療或預防痛風或高尿酸血症之化合物的結晶形式
WO2023125667A1 (en) * 2021-12-30 2023-07-06 Arthrosi Therapeutics, Inc. Preparation of a compound for the treatment of gout or hyperuricemia
US20250242050A1 (en) 2024-01-31 2025-07-31 The Industry & Academic Cooperation In Chungnam National University (Iac) Composition for treating gout containing cyclodextrin-conjugated polymer nano-drug and method for treating gout

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9962362B2 (en) * 2012-03-29 2018-05-08 Children's Hospital Medical Center Use of small molecule inhibitors targeting EYA tyrosine phosphatase
EP3484862B1 (en) * 2016-07-18 2021-09-01 Arthrosi Therapeutics, Inc. Compounds, compositions and methods for treating or preventing a symptom associated with gout or hyperuricemia
US20210130312A1 (en) * 2018-04-03 2021-05-06 Children's Hospital Medical Center Inhibitors of eya3-protein tyrosine phosphatase in dna damage repair signaling of pulmonary arterial hypertension
KR102946486B1 (ko) * 2018-12-06 2026-03-31 아쓰로시 테라퓨틱스, 인크. 통풍 또는 고뇨산혈증의 치료 또는 예방을 위한 화합물의 결정형

Also Published As

Publication number Publication date
JP2022533958A (ja) 2022-07-27
MA55973A (fr) 2022-03-23
JP7656548B2 (ja) 2025-04-03
CN113874014A (zh) 2021-12-31
BR112021022843A2 (pt) 2022-03-03
WO2020232156A1 (en) 2020-11-19
KR20220016105A (ko) 2022-02-08
EP3968989A4 (en) 2022-12-28
IL288034B1 (en) 2026-04-01
SG11202112562XA (en) 2021-12-30
IL288034A (en) 2022-01-01
EP3968989A1 (en) 2022-03-23
MX2021013980A (es) 2022-04-01
AU2026202224A1 (en) 2026-04-09
AU2020274165A1 (en) 2022-01-06
CA3140412A1 (en) 2020-11-19
US20220242841A1 (en) 2022-08-04

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