TW202038719A - Pest repellent composition - Google Patents

Abstract

This pest repellent composition contains components: (A) 13-99.995 mass% of at least one nonvolatile liquid oily component that has a surface tension of not more than 40 mN/m at 25 DEG C, that has a viscosity of not more than 400 mPa.s at 23 DEG C when measured by using a B-type rotational viscometer, and that is selected from the group consisting of silicone oils, ester oils, ether oils, hydrocarbon oils, aliphatic alcohols, and polyhydric alcohols; and (B) 0.005-3 mass% of a repellent component that is at least one selected from N,N-diethyltoluamide, 1-methylpropyl-2-(2-hydroxyethyl)-1-piperidine carboxylate, 3-(acetylbutyl)aminopropionic acid ethyl ester, and para-menthane-3,8-diol.

Description

Pest repellent composition

The present invention relates to a pest repellent composition.

Pests, such as flying pests such as mosquitoes and flies, can cause animal-borne pathogens such as humans to cause infections or dermatitis. In particular, some mosquitoes are vector dengue fever, Zika fever, yellow fever, encephalitis, malaria and other pathogens, so they are very harmful insects in terms of hygiene. Previously, in order to avoid the infestation of such flying insects, the general method was to spray insecticides or apply repellents on the skin surface. As a representative repellent, DEET (N,N-diethyl toluamide) ).

Mosquitoes and other pests have chemosensory systems such as thermoreceptors for sensing animal body temperature, olfactory receptors for sensing body odor and other volatile substances, and carbon dioxide receptors for sensing carbon dioxide, so as to detect animals. DEET The chemosensory system exerts modulation to weaken the perception and perception of pests, thereby avoiding pests. However, DEET has an unpleasant odor. In addition, it is necessary to prepare a certain amount or more in order to exert a sufficient repellent effect. Furthermore, it is known that it can cause allergies or chapped skin depending on the person, and there is a problem of limited use amount or frequency of use for young children or people with sensitive muscles.

Therefore, there are studies using natural essential oils as deterrents. Natural essential oils such as citronella oil, lemon eucalyptus oil, lemongrass oil, orange peel oil, cinnamon oil are also used in candles or aromatherapy lotions, which are safer for the human body. However, the continuous effect of the repellent against pests is not sufficient, and there are problems with its practicality.

In addition, various proposals have been made regarding repellents or repellent compositions for pests. For example, Patent Document 1 describes that an insect repellent such as DEET is formulated in a skin protectant blended with fluorine-polyether co-modified silicone and ultraviolet protection components. Patent Document 2 describes that it can be enhanced by using a pest repellent component containing 3-(acetylbutyl)aminopropionate and/or N,N-diethyltoluamide in combination with an antibacterial compound Pest repellent effect. [Prior technical literature] [Patent literature]

Patent Document 1: Japanese Patent Laid-Open No. 8-59447 Patent Document 2: Japanese Patent Laid-Open No. 2016-102092

The present invention provides the following [1] to [7]. [1] A pest repellent composition or pest retention inhibitory composition, which contains the following components (A) and (B): (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 99.995% by mass (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass%. [2] An oil-in-water type mosquito repellent composition or mosquito retention inhibiting composition containing the following components (A) to (C), and the content of pest repellents other than component (A) and component (B) is 15 Below mass%, (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass; (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.01% by mass to 3% by mass; (C) Water: 35 mass% or more and 86.995 mass% or less. [3] An oil-in-water type mosquito repellent composition or mosquito retention suppression composition containing the following components (A) to (C), and the mass ratio of component (A) to component (C) [(A)/( C)] is 0.15 or more and 1.6 or less, and the content of pest repellents other than ingredient (A) and ingredient (B) is 15% by mass or less, (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass; (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass%; (C) Water: 35 mass% or more and 86.995 mass% or less. [4] An oil-in-water type mosquito repellent composition or mosquito retention inhibitor composition containing the following components (A) to (C), the mass ratio of component (A) to component (B) [(A)/( B)] is 7 or more and 3000 or less, and the mass ratio of component (A) to component (C) [(A)/(C)] is 0.15 or more and 1.6 or less, and pest repellent other than component (A) and component (B) The content is 15% by mass or less, (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass; (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass%; (C) Water: 35 mass% or more and 86.995 mass% or less. [5] An oil-in-water type mosquito repellent composition or mosquito retention suppression composition, which contains the following components (A) to (D), the mass ratio of component (A) to component (B) [(A)/( B)] is 7 or more and 3000 or less, and the mass ratio of component (A) to component (C) [(A)/(C)] is 0.15 or more and 1.6 or less, and pest repellent other than component (A) and component (B) The content is 15% by mass or less, (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil and hydrocarbon oil. One or more non-volatile liquid oily components in the composition group: 13% by mass to 50% by mass; (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass%; (C) Water: 35 mass% or more and 86.995 mass% or less; (D) Tackifier: 0.05% by mass to 5% by mass. [6] A method for repelling pests, which involves applying the composition of any one of [1] to [5] on the surface of human skin. [7] A method for inhibiting the staying of pests, which prevents the pests from staying on human skin by attaching the composition of any one of [1] to [5] to the limbs of the pests.

[Pest repellent composition, pest staying inhibitory composition] The pest repellent composition and pest retention inhibitory composition of the present invention (hereinafter also collectively referred to as "the composition of the present invention") are compositions containing the following components (A) and (B). (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily ingredients in the group consisting of aliphatic alcohols and polyols: 13% by mass to 99.995% by mass (B) selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group Ethyl propionate and p-menthane-3,8-diol consisting of one or more repellent active ingredients: 0.005 mass% to 3 mass%

The composition of the present invention contains specific amounts of component (A) and component (B), has excellent repellent effect on pests, especially flying pests, has less unpleasant odor due to specific repellent components, and is suitable for skin application The composition.

Regarding the application to the skin of the pest repellent, it is expected that it is safe and has less odor, and not only the initial repellent effect, but also the durability of the repellent effect is excellent. However, the current status quo is that the main pest repellents available do not fully meet these expectations. As mentioned above, the existing pest repellents such as DEET described in Patent Documents 1 and 2 have an unpleasant smell, and there are also problems in the safety of the human body. Therefore, it is required to be suitable for young children or people with sensitive muscles. A repellent for safe use. At present, there has not been found a composition suitable for skin application that has excellent pest repellent effect and persistence, and suppresses unpleasant odors derived from repellent ingredients.

The subject of the present invention is to provide a pest repellent composition that has excellent repellent effect on pests, especially flying pests, and has excellent persistence, safety, and less unpleasant odor derived from repellent ingredients, suitable for skin application.

After intensive research, the inventors found that non-volatile liquid oily ingredients with specific surface tension and viscosity have the effect of repelling insects such as mosquitoes, but when actually used on human skin, the repellent effect continues There is still room for further research on sex. Therefore, it has been found that if the content of existing pest repellent components such as N,N-diethyltoluidine is set to a level that does not cause unpleasant odor problems, and is consistent with the non-volatile properties of specific surface tension and viscosity The combination of liquid oily ingredients not only suppresses unpleasant odors, but also prolongs the repellent effect. That is, it has been found that a pest repellent composition containing a specific amount of a non-volatile liquid oily component having a specific surface tension and viscosity, and a repellent component such as N,N-diethyl toluamide can solve the above-mentioned problems. According to the present invention, it is possible to provide a pest repellent composition that has excellent repellent effects on pests, especially flying pests, is safe, has less unpleasant odor derived from specific repellent ingredients, and is suitable for skin application, and pest staying inhibitory combination Methods of avoiding pests, pests, and methods of staying and restraining pests.

In the present invention, the so-called "repellent effect on pests" means that even if the pests contact the object, they will not stay and leave immediately, and the composition of the present invention is equivalent to a contact repellent composition. That is, the pest repellent effect in the present invention is different from a repellent or insect repellent that achieves the purpose of repelling by non-contact with the target, such as a person who does not allow the pest to approach the object or a person who does not approach the object. Pests are insecticides that have insecticidal power and repel pests. The composition of the present invention exerts the effect of repelling the pests by leaving the pests without staying on the spot even if the pests such as mosquitoes land on the object to which the composition is applied or attached. Specifically, it has the following stay-inhibiting effect: after mosquitoes and other pests land on the skin of humans and other animals, they will not stay in a specific area on the skin surface for about the time required to penetrate the needle, specifically 1 second Above the clock. This effect is based on the previously unseen principle of repelling pests, and is relatively safe, without side effects such as skin cracking. Therefore, the composition of the present invention can be used as a pest stay inhibitory composition. In the present invention, the "continuing effect of repelling pests" means that after applying the composition of the present invention to an object, the repelling effect continues to be effective even after a period of time. Furthermore, in the following description, the continuous effect of repelling pests in the present invention, especially for flying pests, is briefly described as "continuing effect of repelling."

The composition of the present invention contains a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-shaped rotary viscometer selected from (a) silicone oil, (b) )Ester oil, (c) ether oil, (d) hydrocarbon oil, (e) aliphatic alcohol, and (f) polyhydric alcohol are composed of one or more non-volatile liquid oily components as component (A) . By containing ingredient (A), it has an excellent repellent effect on pests, especially flying pests. The reason for this has not yet been determined, but it is thought to lie in the following. The inventor found that flying insects such as mosquitoes have the following characteristics: in order to avoid the gravitational force generated from the landing surface when the limbs are wet, they avoid staying on the surface of the wet limbs. Since the limbs of flying pests such as mosquitoes are hydrophobic, if it is a liquid oily component with a surface tension of 40 mN/m or less at 25°C, the affinity with the limbs of flying pests will become higher, and if the viscosity is For liquid oily components below 400 mPa·s, when the limbs of flying pests come into contact with the liquid oily components, the contact area between the liquid oily components and the limbs of flying pests will be sufficiently enlarged in a short time. Therefore, it is believed that if flying pests land on a surface coated with or attached to component (A), their limbs will be wetted and will avoid the gravitational force generated from the landing surface at this time, and will not stay at the landing site and fly away. Furthermore, the term “landing” in the present invention refers to the time when flying insects such as mosquitoes and the object are in contact with the object for less than 1 second. In addition, the term “stay” in the present invention refers to a period of time during which flying insects such as mosquitoes and the object continue to contact the object for more than 1 second.

In addition, if the composition of the present invention contains the component (A) alone, there is still room for improvement in terms of sufficient repellent and sustained effects during actual use. Therefore, in addition to the component (A), the composition further contains less than a specific amount The aforementioned ingredient (B) is believed that by applying ingredient (A) and ingredient (B) to the limbs of flying insects, the unpleasant odor derived from ingredient (B) can be reduced while achieving excellent avoidance Lasting effect.

<Component (A): Non-volatile liquid oily component> The component (A) contained in the composition of the present invention has a surface tension of 40 mN/m or less at 25°C, and a viscosity of 400 mPa·s or less at 23°C as measured by a B-shaped rotary viscometer, selected from (a) Polysiloxane oil, (b) ester oil, (c) ether oil, (d) hydrocarbon oil, (e) aliphatic alcohol, and (f) polyhydric alcohol in a non-volatile liquid state Oily ingredients.

Component (A) is preferably liquid at 20°C, more preferably liquid at 15°C, and still more preferably liquid at 10°C, from the viewpoint of easy application to the skin and improved repellent effect Non-volatile oil. Furthermore, the so-called "liquid" of liquid oily ingredients means the determination of liquid-solid based on the American Society for Testing and Materials standard "ASTM D 4359-90: Standard Test Method for Determining Whether a Material is a Liquid or Solid" It is judged as liquid by the test. Component (A) is preferably a poorly water-soluble or water-insoluble component from the viewpoint of enhancing the continuous effect of repelling pests. Specifically, the dissolved amount in 100 g of water at 20°C is preferably 1 g Below, it is more preferably 0.5 g or less, still more preferably 0.1 g or less, and still more preferably substantially 0 g or more.

The liquid oily component of the component (A) used in the present invention is a non-volatile liquid oily component from the standpoint of enhancing the repellent persistence effect. Here, the so-called non-volatile liquid oily component in the present invention refers to those having a volatility rate of 50% or less after drying at 1 atmosphere, 25°C, and 60 minutes, preferably at 1 atmosphere, 25°C, and 120%. The volatilization rate after drying in minutes is below 50%. The evaluation of volatility is measured according to the German test standard DIN53249, specifically, according to the following procedures 1 to 4. 1. Measure the weight (P(g)) of a round filter paper with a diameter of 150 mm. 2. Use a pipette to drop a sample of component (A) 0.3 g on the round filter paper, and then immediately measure the weight of the filter paper (W ₀ (g)). 3. Under airtight conditions, measure the weight of the filter paper with an accuracy of about 0.001 g after 5 minutes at 25°C. The weight of the filter paper measured after 60 minutes has elapsed from the measurement of Procedure 2 is set to W ₆₀ (g). 4. The value derived by the calculation formula {((W ₀ -P)-(W ₆₀ -P))/(W ₀ -P)}×100 is regarded as the volatilization rate (%). The lower the volatilization rate, the longer the retention time of the liquid oily ingredients when applied to the skin, and therefore the higher the repellent effect. When two or more types of liquid oily components are used, the so-called nonvolatile liquid oily component volatility rate means the volatility rate of a mixture of two or more liquid oily components. Therefore, as long as the volatilization rate of the mixture is in the above-mentioned range, it can also be used in combination with liquid oily components that have a volatilization rate exceeding 50% after drying at 1 atmosphere and 25°C for 60 minutes.

Regarding the surface tension of the component (A) at 25° C., from the viewpoint of availability, it is preferably 15 mN/m or more, more preferably 17 mN/m or more, and from the viewpoint of improving the repellent effect 40 mN/m or less, preferably 30 mN/m or less, more preferably 28 mN/m or less, still more preferably 25 mN/m or less, still more preferably 23 mN/m or less, still more preferably 21 mN /m or less. In addition, even if the surface tension of itself at 25°C exceeds 40 mN/m, if it is made into a mixture with other liquid oily components to reduce the surface tension, it also exhibits a repellent effect. Regarding the viscosity of component (A) at 23°C measured with a B-shaped rotary viscometer, it is preferably 1 mPa·s or more from the viewpoint of suppressing volatility and improving the effect of repelling persistence, and from the viewpoint of improving the effect of repellent persistence 400 mPa·s or less, preferably 300 mPa·s or less, more preferably 210 mPa·s or less, still more preferably 100 mPa·s or less, still more preferably 60 mPa·s or less, still more preferably 40 mPa·s or less, more preferably 30 mPa·s or less. In addition, when two or more liquid oily components with different viscosities are used, it means the viscosity as a mixture of these liquid oily components. In addition, the surface tension and viscosity of component (A) are measured by the methods described in the examples.

(a) Polysiloxane oil As the silicone oil, from the viewpoint of enhancing the effect of repellent retention, it is preferably selected from the group consisting of dimethylpolysiloxane, Dimethiconol (Dimethiconol with a hydroxyl group at the end) Alkane), methyl phenyl polysiloxane, and modified polysiloxane. Examples of modified silicone include: amino modified silicone (dimethylpolysiloxane containing amine groups in the molecule), polyether modified silicone, glyceryl modified silicone, amine -Based derivatives polysiloxane, carboxyl modified polysiloxane, fatty acid modified polysiloxane, alcohol modified polysiloxane, aliphatic alcohol modified polysiloxane, epoxy modified polysiloxane, fluorine modified polysiloxane Oxygen, alkyl modified polysiloxane, etc.

Among the polysiloxane oils, from the viewpoint of enhancing the effect of repellent retention, it is preferably selected from the group consisting of dimethyl polysiloxane, dimethiconol, methyl phenyl polysiloxane and modified polysiloxane. One or more of the group consisting of silicone, more preferably one or more selected from the group consisting of dimethyl polysiloxane, dimethicone and polyether modified polysiloxane, More preferably, it is dimethyl polysiloxane.

As the dimethylpolysiloxane, one or more selected from the group consisting of linear dimethylpolysiloxane and cyclic dimethylpolysiloxane can be mentioned. Among them, from the viewpoint of enhancing the effect of repelling the sustained effect, the linear dimethyl polysiloxane is more preferable. Examples of commercially available linear dimethyl polysiloxanes include: KF-96 series of Shin-Etsu Chemical Co., Ltd., SH200C series of Dow Corning Toray Co., Ltd., "2-1184 Fluid", Momentive Performance Materials' "Silsoft DML", "Element14 PDMS 5-JC", "Element14 PDMS 10-JC", "Element14 PDMS 20-JC", etc.

(b) Ester oil As the ester oil, from the viewpoint of enhancing the effect of repellency, the ester oil represented by any one of the following general formulas (1) to (3) and the carbonic acid represented by the following general formula (4) are preferred Dialkyl ester compounds.

R ¹ -COO-R ² (1) In the general formula (1), R ¹ can be substituted by a hydroxyl group and represents a straight or branched alkyl group with carbon number 7 or more and 23 or less, or carbon number 6 or more and 24 or less In the aromatic hydrocarbon group, R ² represents a linear or branched alkyl group or alkenyl group having 1 to 22 carbon atoms. In the case where R ¹ is an alkyl group, the carbon number is preferably 7 or more, more preferably 9 or more, from the viewpoint of enhancing the repellent persistence effect, and from the viewpoint of making the touch on the skin good , Preferably 21 or less, more preferably 17 or less. In addition, when R ¹ is an aromatic hydrocarbon group, from the viewpoint of enhancing the repellent effect, the carbon number is preferably 8 or more, more preferably 10 or more, and it makes the touch on the skin good From a viewpoint, it is preferably 22 or less, and more preferably 20 or less. R ² is preferably a linear or branched alkyl group or alkenyl group having a carbon number of 20 or less, and more preferably 18 or less, from the viewpoint of improving the touch when applied to the skin. In addition, from the viewpoint of improving the touch when applied to the skin, it is preferable that at least one of R ¹ or R ² is a branched alkyl group.

The ester oil represented by the general formula (1) may be selected from the group consisting of myristyl 2-ethylhexanoate, cetyl 2-ethylhexanoate, stearyl 2-ethylhexanoate, and isodecyl caprylate , Isocetyl caprylate, Isononyl isononanoate, Isononyl isononanoate, Cetyl isononanoate, Octyl propyl heptanoate, Methyl laurate, Isopropyl myristate , Octyl dodecyl myristate, isopropyl palmitate, 2-ethylhexyl palmitate, isocetyl palmitate, 2-ethylhexyl stearate, isocetyl stearate , Isotridecyl stearate, isopropyl isostearate, octyl isostearate, isocetyl isostearate, isostearyl isostearate, 2-ethyl hydroxystearate Hexyl hexyl ester, methyl oleate, oleyl oleate, isobutyl oleate, oleyl erucate, alkyl benzoate (alkyl with 12 to 15 carbon atoms) and diethylhexyl naphthalate, etc. One or more species in the group that it forms.

(R ³ O)-CH ₂ CH(OR ⁴ )-CH ₂ (OR ⁵ ) (2) In the general formula (2), R ³ , R ⁴ and R ⁵ are each independently a hydrogen atom or the following general formula The groups represented by (2-1) are not all hydrogen atoms. -CO-R ⁶ (2-1) (In the formula, R ⁶ represents an alkyl group or alkenyl group with a carbon number of 7 or more and 23 or less, preferably 17 or less, which may be substituted by a hydroxyl group) as represented by the general formula (2) The ester oil includes one or more selected from the group consisting of tris(2-ethylhexanoic acid) glyceride and tricaprylic acid glyceride. It can also be such jojoba oil, olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grapeseed oil, thistle oil, and balsam Oil, Australian walnut oil, corn germ oil and calyx pear oil and other plant-derived ester oils.

R ⁷ O-(AO)m-COR ⁸ (3) In the general formula (3), R ⁷ represents an aromatic hydrocarbon group with a carbon number of 6 to 20 and R ⁸ represents an alkyl group or alkene with a carbon number of 1 to 23 base. AO represents an alkoxylate having a carbon number of 2 to 4, and m represents an average number of added moles of 1 to 50. R ⁷ is preferably a carbon number of 6 or more from the viewpoint of enhancing the effect of repelling the persistence, and from the viewpoint of making the touch on the skin good, it is preferably 12 or less, more preferably 10 or less aromatic The group hydrocarbon group is more preferably a benzyl group. R ⁸ is preferably carbon number 7 or more, more preferably 11 or more, from the viewpoint of improving the effect of repelling continuation, and from the viewpoint of making the touch on the skin good, it is preferably 21 or less, more Preferably, it is an alkyl group of 15 or less. From the viewpoint of enhancing the repellent persistence effect, the AO group is preferably propyleneoxy group. From the viewpoint of enhancing the repellent persistence effect and making the touch on the skin good, m is preferably 1 or more 10. Below, it is more preferably 1 or more and 5 or less. As the ester oil represented by the general formula (3), three mol adducts of propylene oxide selected from benzyl alcohol and esters of myristic acid ("Crodamol STS" of Croda) and propylene oxide of benzyl alcohol can be cited 3 mol adduct and 2-ethylhexanoic acid ester (Crodamol SFX from Croda) is one or more of the group.

R ⁹ -O-(CH ₂ CH ₂ O)v-CO-(OCH ₂ CH ₂ )w-OR ¹⁰ (4) In the general formula (4), R ⁹ and R ¹⁰ each independently represent a carbon number of 6 or more For alkyl or alkenyl groups of 22 or less, v and w each independently represent an average number of added moles of 0 or 1 to 50. R ⁹ and R ¹⁰ have a carbon number of 8 or more from the viewpoint of enhancing the effect of repelling continuation, and from the viewpoint of making the touch on the skin good, they are preferably 18 or less, more preferably 12 The following alkyl groups. From the viewpoint of improving the touch when applied to the skin, v and w are preferably 0 or a number of 1 to 5, and more preferably 0. As the dialkyl carbonate compound represented by the general formula (4), dioctyl carbonate ("CETIOL CC" by Cognis) and the like can be cited.

Examples of ester oils other than the above include esters of polycarboxylic acids and alcohols, or esters of polyhydric alcohols and fatty acids other than glycerin. As a specific example, it can be selected from the group consisting of diisopropyl dimer acid, diisopropyl adipate, diethoxyethyl succinate, 2-ethylhexyl succinate, and propanediol didecanoate. One or more of the group consisting of neopentyl glycol dicaprate, neopentyl glycol di(2-ethylhexanoate), etc. Among them, from the viewpoint of enhancing the effect of repelling, it is preferably an ester of neopentyl glycol and fatty acid, and more preferably selected from neopentyl glycol didecanoate and bis(2-ethylhexanoic acid) One or more of the group consisting of neopentyl glycol esters. Among the above-mentioned (b) ester oils, one or more selected from the group consisting of ester oils represented by general formula (1), and esters of neopentyl glycol and fatty acids are preferred.

(c) Ether oil The ether oil is preferably a dialkyl ether compound represented by the following general formula (5), or a polyoxyalkylene alkylene represented by the following general formula (6) from the viewpoint of enhancing the effect of repellency基Ether compound.

R ¹¹ -OR ¹² (5) In the general formula (5), R ¹¹ and R ¹² each independently represent a linear or branched alkyl or alkenyl group with 6 or more and 22 or less carbon atoms, or 6 or more and 24 or less carbon atoms The aromatic hydrocarbon group. R ¹¹ and R ¹² are preferably an alkyl group from the viewpoint of enhancing the effect of repelling continuity, and its carbon number is preferably 8 or more from the viewpoint of enhancing the effect of repelling continuance, and it is suitable for contact with the skin. From the viewpoint of a good feeling, it is preferably 18 or less, more preferably 16 or less, and still more preferably 12 or less. Examples of the dialkyl ether compound represented by the general formula (5) include: dihexyl ether, dioctyl ether ("CETIOL OE" of Cognis), dioctyl ether, and cetyl-1,3-dimethyl Butyl Ether (“ASE-166K” of Kao Co., Ltd.), etc.

R ¹³ -O-(PO)r(EO)sH (6) In the general formula (6), R ¹³ represents an alkyl or alkenyl group with a carbon number of 6 or more and 22 or less, PO represents an propyleneoxy group, and EO represents an extension Ethoxy. r represents the average number of added moles from 0.1 to 15 and s represents the average number of added moles from 0 to 10. When s is not 0, the addition form of PO and EO can be random or block. The carbon number of R ¹³ is preferably 8 or more from the standpoint of enhancing the effect of repellency, and from the standpoint of making the touch on the skin good, it is preferably 20 or less, more preferably 18 or less. More preferably, it is 12 or less. The average number of added moles r is preferably 1 or more, more preferably 2 or more, and still more preferably 3 or more from the viewpoint of enhancing the repellent continuity effect, and from the viewpoint of making the touch on the skin good In particular, it is preferably 13 or less, more preferably 10 or less, and the average added molar number s is preferably 5 or less, more preferably 1 or less from the viewpoint of making the touch on the skin good, and further Preferably it is 0. The polyoxypropylene alkyl ether compound represented by the general formula (6) is preferably a polyoxypropylene octyl ether selected from the group consisting of polypropylene glycol and propyleneoxy whose average addition molar number r is 3 to 10 , Polyoxypropylene decyl ether and polyoxypropylene lauryl ether consisting of more than one species. Among the above-mentioned (c) ether oils, the ether oil represented by the general formula (5) is preferred from the viewpoint of enhancing the repellent continuation effect.

(d) Hydrocarbon oil Examples of hydrocarbon oils include: liquid paraffin, liquid isoparaffin, squalane, isohexadecane, isoeicosane, hydrogenated polyisobutylene, light liquid isoparaffin, heavy liquid isoparaffin, α-olefin Oligomers and cycloparaffins, etc. Among them, from the viewpoint of enhancing the effect of repellency and making the touch feel good when applied to the skin, it is preferably selected from the group consisting of liquid paraffin, liquid isoparaffin and squalane 1 or more.

(e) Fatty alcohol Examples of the aliphatic alcohol include monovalent chain or cyclic aliphatic alcohols, and from the viewpoint of enhancing the repellent persistence effect, monovalent chain aliphatic alcohols are preferred. The carbon number of the aliphatic alcohol is preferably 14 or more, and more preferably 18 or more in average carbon number from the viewpoint of enhancing the effect of repellency, and it is more preferable from the viewpoint of making the touch on the skin good It is 28 or less, more preferably 24 or less, and still more preferably 22 or less aliphatic alcohol. The above-mentioned aliphatic alcohol may be any of straight chain and branched chain, saturated and unsaturated, and it is preferable from the viewpoint of enhancing the effect of repellency and keeping the touch on the skin good. It is a branched aliphatic saturated alcohol. Examples of linear aliphatic alcohols include oleyl alcohol, and examples of branched aliphatic saturated alcohols include butyl octanol, butyl decanol, hexyl decanol, and octyldodecanol. Among them, from the viewpoint of enhancing the effect of repelling and making the touch on the skin good, the branched aliphatic saturated alcohol is preferably selected from the group consisting of hexyl decanol and hexyl dodecyl alcohol. One or more of the group consisting of alkanol and octyldodecanol.

(f) Polyol Examples of polyhydric alcohols include: aliphatic alcohols with 2 or more carbons, aromatic alcohols, sugar alcohols with 4 or more carbons, etc. The polyols can be saturated or unsaturated, which makes the touch feel good when applied to the skin. From a viewpoint, it is preferably at least one selected from the group consisting of aliphatic alcohols having 2 to 10 carbon atoms, aromatic alcohols, and sugar alcohols having 4 to 10 carbon atoms. Examples of aliphatic alcohols with 2 or more carbons in the polyol include: ethylene glycol, propylene glycol, 1,2-butanediol, 1,3-butanediol, 1,2-pentanediol, 1,2 -Dihydric alcohols such as hexanediol, diethylene glycol, dipropylene glycol, hexanediol, etc. Moreover, as said sugar alcohol, sorbitol, erythritol, pentaerythritol, xylitol, mannitol, etc. are mentioned.

Among the above-mentioned liquid oily components, from the viewpoint of enhancing the repellent effect, it is preferably selected from (a) silicone oil, (b) ester oil, (c) ether oil and (d) hydrocarbon oil. One or more of the group, more preferably one or more selected from the group consisting of (a) silicone oil, (b) ester oil, and (d) hydrocarbon oil, more preferably selected from (a) ) One or more of the group consisting of silicone oil and (b) ester oil, and more preferably (a) silicone oil. (a) Among the polysiloxane oils, from the viewpoint of improving the effect of repelling the lasting effect, it is preferably selected from the group consisting of dimethyl polysiloxane, dimethicone, methyl phenyl polysiloxane and One or more of the group consisting of modified polysiloxane, more preferably one selected from the group consisting of dimethyl polysiloxane, dimethicone and polyether modified polysiloxane More than one kind, more preferably dimethylpolysiloxane, and even more preferably linear dimethylpolysiloxane.

(Content of ingredient (A)) Regarding the content of the component (A) in the composition of the present invention, from the viewpoint of enhancing the effect of repellent retention, it is 13% by mass or more, preferably 20% by mass or more, and more preferably 25% by mass or more. From the viewpoint of the effect, the viewpoint of suppressing the odor derived from the component (A), the viewpoint of improving the usability of the composition, and the viewpoint of ensuring the long-term storage stability of the composition, it is 99.995% by mass or less, preferably 80% by mass % Or less, more preferably 50% by mass or less, still more preferably 40% by mass or less, and still more preferably 35% by mass or less. Therefore, the content of the component (A) in the composition of the present invention is 13 to 99.995% by mass, preferably 13 to 80% by mass, more preferably 13 to 50% by mass, and still more preferably 20 to 40% by mass, It is more preferably 25 to 40% by mass, and still more preferably 25 to 35% by mass.

＜Component (B): Avoid component＞ The composition of the present invention contains selected from the group consisting of N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl) ) Ethyl aminopropionate and one or more repellent active ingredients from the group consisting of p-menthane-3,8-diol are used as ingredient (B). In the following description, N,N-diethyltoluamide is also referred to as "DEET", and 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester is referred to as "Icaridin" refers to ethyl 3-(acetylbutyl)aminopropionate as "IR3535", and p-menthane-3,8-diol as "PMD". Component (B) is an existing pest repellent, and its repellent effect is well known, but if the content is more than the effective amount, specifically if it is contained in the composition more than 4% by mass, it will give off an irritating effect from component (B) The unpleasant smell may also cause skin problems such as macula. Therefore, in the composition of the present invention, by setting the content of the component (B) to a level where these problems do not exist and combining the component (A) to use, the irritation derived from the component (B) can be reduced. Unpleasant smell, and to ensure the continuous effect and safety of avoidance. Component (B) may be contained individually by 1 type, or may contain 2 or more types. Among the components (B), from the viewpoint of enhancing the repellent effect, it is preferably selected from N,N-diethyltoluidine and 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1 -One or more repellent ingredients in the group consisting of methyl propyl ester, from the viewpoint of ensuring the long-term storage stability of the composition, it is preferably selected from N,N-diethyl toluamide and para Menthane-3,8-diol is one or more repellent ingredient in the group. Furthermore, PMD can be synthesized, or essential oil obtained by refining natural eucalyptus oil (Eucalyptus citriodora) or increasing PMD content. In any case, the content of PMD may be included in the composition so that the content of PMD falls within the specified range of the component (B) of the present invention. Examples of essential oils containing PMD include lemon oil (oil of lemon eucalyptus/OLE), Citrosynthol (Novosynth), Citrepel (CHEMIAN TECHNOLOGY), Citriodiol (Citrefine), and the like.

(Content of ingredient (B)) The content of the component (B) in the composition of the present invention is 0.005% by mass or more, preferably 0.01% by mass or more, from the viewpoint of enhancing the repellent effect and suppressing the odor derived from the component (A), It is more preferably 0.05% by mass or more, still more preferably 0.1% by mass or more, still more preferably 0.5% by mass or more, and still more preferably 0.8% by mass or more. In addition, the content of the component (B) in the composition of the present invention is from the viewpoint of suppressing the unpleasant smell, allergies or skin cracks derived from the component (B), and from the viewpoint of ensuring the long-term storage stability of the composition It is 3% by mass or less, preferably 2.5% by mass or less, more preferably 2.2% by mass or less, still more preferably 2% by mass or less, still more preferably 1.8% by mass or less, and still more preferably 1.5% by mass or less. Therefore, the specific range of the content of the component (B) in the composition of the present invention is 0.005 to 3% by mass, preferably 0.01 to 2.5% by mass, more preferably 0.05 to 2.2% by mass, and still more preferably 0.1 to 2.2 Mass %, more preferably 0.1 to 2 mass %, still more preferably 0.5 to 2 mass %, still more preferably 0.5 to 1.8 mass %, still more preferably 0.8 to 1.5 mass %.

The content of the aforementioned component (B) is an amount that does not reach the effective amount of the pest repellent as the component (B). As the effective amount of the pest repellent of ingredient (B), please refer to the minimum effective amount disclosed by the manufacturer of each repellent product. More specifically, the effective amount of DEET is 4% by mass or more, preferably 10% by mass or more, the effective amount of Icaridin is 4% by mass or more, ethyl 3-(acetylbutyl)aminopropionate The effective amount of ester is 4% by mass or more, and the effective amount of menthane-3,8-diol is 4% by mass or more.

In addition, the composition of the present invention contains component (A) and component (B) as repellent components to deal with pest repellency, and does not contain other pest repellents in an effective amount, thus preventing the user from allergies or skin cracking. In terms of better. Even if the composition of the present invention does not contain a pest repellent other than the component (A) and the component (B) in an effective amount, it still has a repellent sustained effect. In other words, if the composition of the present invention contains pest repellents other than ingredient (A) and ingredient (B) in an amount that does not reach the lower limit of the effective amount, the pests will not stay in place even if they fall. That is to show the stay suppression effect of the present invention. That is, the composition of the present invention may be substantially free of existing pest repellents other than component (A) and component (B).

Here, the so-called "not contained in an effective amount" pest repellents other than component (A) and component (B) generally refer to pest repellents other than component (A) and component (B) in the composition of the present invention The content of the agent is preferably 15% by mass or less, more preferably 10% by mass or less, still more preferably 5% by mass or less, still more preferably 4% by mass or less, still more preferably 3% by mass or less, and still more preferably 1% by mass or less. The effective amount of existing pest repellents other than ingredient (B) can also refer to the minimum effective amount disclosed by the manufacturer of each repellent product. For example, among existing pest repellents other than ingredient (B), the effective amount of citronella oil is more than 10% by mass. Therefore, in the present invention, setting the content of citronella oil to 5 mass% or less is one of the preferred forms of the present invention, and it is more preferable if it is 1 mass% or less.

In addition, the effective amount of the existing pest repellent can also be measured by the repellent evaluation test described below. (Repellency evaluation test) Put 100 female mosquitoes (Aedes albopictus) that have copulated into a plastic cage (30×30×30 cm: BugDorm-1 cage) surrounded by a grid. Extend your arm to the elbow about 15 cm away from the wrist to cut out Qualatex ultra-long gloves (KUALATEC SuperLongGloves) (50 cm) with a rectangular incision of 5 cm x 4 cm (50 cm) (ASONE Co., Ltd., product code (Catalog number): 3-6432-02). Without applying any application to the area exposed from the incision, extend your arm into the cage, confirm that mosquitoes have dropped on 2 places on the bare skin within 2 minutes, and stay for more than 1 second. If you haven't stayed for more than 1 second, prepare the mosquitoes again. Hereinafter, the stay of more than 1 second is simply referred to as stay. The test of the evaluation sample as the solution of the pest repellent was carried out after adjusting the concentration using ethanol so that the evaluation sample could be applied to the bare skin area (5 cm×4 cm) at 2 mg/cm ² . Using PIPETMAN, drop the adjusted concentration of the solution onto the exposed area and spread it over the entire exposed area of the skin (required solution volume: 40-50 μl). After that, let it stand for 3 minutes and start the test. The test was performed by extending the arm coated with the evaluation sample into the cage for 2 minutes and counting the number of stays. The time when there are 2 stays in total is considered the end of the test. Before the end of the test, the arms are extended for 2 minutes every 30 minutes for the test. If there is a second stay at the 30th minute, the duration of the repellent effect is determined to be 0 minutes, and if there is a second stay at the 60th minute, the duration of the repellent effect is determined to be 30 minutes. The test was conducted by 3 subjects, and the average duration of the repellent effect was calculated. In this test, the concentration of the pest repellent that shows an average duration of the repelling effect of more than 2 hours can be set as the effective concentration (effective amount) of the pest repellent. Even if the composition of the present invention does not contain pest repellents other than component (A) and component (B) in an effective amount, it has a repellent sustained effect. Therefore, it suppresses the irritation of pest repellents derived from components other than component (B). From the viewpoint of unpleasant smell or strong odor, and the viewpoint of preventing skin problems, it is more preferable not to contain a pest repellent other than ingredient (A) and ingredient (B). In the composition of the present invention, the content of the pest repellent other than component (A) and component (B) is preferably 0.5% by mass or less, more preferably 0.1% by mass or less, and still more preferably 0.01% by mass or less, and further More preferably, it is substantially 0% by mass.

Existing pest repellents other than ingredient (A) and ingredient (B) include: dimethyl phthalate, 2-ethyl-1,3-hexanediol, and p-menthane-3,8- Glycol, carane-3,4-diol, di-n-butyl succinate, hydroxyanisole, rotenone, citronellol, eucalyptol, α-pinene, geraniol, citronellal, Well-known pest repellent compounds such as camphor, linalool and 2-undecone, as well as repellent essential oils such as citronella oil, lemongrass oil, eucalyptus oil, peppermint oil, and catnip oil. The so-called "repellent essential oils" refer to those essential oils (essential oils) obtained by extracting, distilling or squeezing the ingredients contained in plants that have pest repellent effects.

In the composition of the present invention, the mass ratio of component (A) to component (B) [(A)/(B)] is preferably 7 or more from the viewpoint of suppressing unpleasant odors, more preferably It is 13 or more, more preferably 25 or more, and it is preferably 3000 or less, more preferably 300 or less, still more preferably 100 or less, and still more preferably 50 or less from the viewpoint of enhancing the repellent sustained effect. Therefore, the mass ratio [(A)/(B)] of the component (A) to the component (B) is preferably 7 to 3000, more preferably 7 to 300, still more preferably 13 to 300, and still more preferably 13 ～100, more preferably 13-50, still more preferably 25-50.

＜Component (C): Water＞ From the viewpoint of enhancing the repellent effect and the viewpoint of producing a composition with a good feeling of use, the composition of the present invention preferably contains water as the component (C). Regarding the content of the component (C) in the composition, it is preferably 5% by mass or more, more preferably 10% by mass or more, from the viewpoint of improving the repellent effect and the viewpoint of making a composition with good feeling in use. It is preferably 35% by mass or more, and more preferably 50% by mass or more. Moreover, from the viewpoint of enhancing the repellent continuation effect, it is preferably 86.995% by mass or less, more preferably 85% by mass or less, still more preferably 80% by mass or less, and still more preferably 75% by mass or less. Therefore, the content of the component (C) in the composition is preferably 5 to 86.995% by mass, more preferably 5 to 85% by mass, still more preferably 10 to 80% by mass, and still more preferably 35 to 75% by mass, More preferably, it is 50 to 75% by mass.

The present invention can be applied to various forms of compositions. For example, it can be used in non-aqueous compositions containing no moisture, water-in-oil compositions, oil-in-water compositions, etc., to suppress the odor derived from ingredient (A) From the viewpoint of taste, it is preferably made into an oil-in-water type composition. Furthermore, when making an oil-in-water type composition, the content of the component (C) in the composition is preferably 35% by mass or more from the viewpoint of ensuring the long-term storage stability of the composition, more preferably It is 40% by mass or more, more preferably 45% by mass or more. Furthermore, from the viewpoint of enhancing the repellent continuation effect, it is preferably 86.995 mass% or less, more preferably 80 mass% or less, and more preferably 75 mass% or less. In addition, from the viewpoint of enhancing the effect of repellent retention, it is preferable to form a water-in-oil type composition. Furthermore, in the case of making a water-in-oil type composition, the content of the component (C) in the composition is 5% by mass or more from the viewpoint of making the touch feel good when applied to the skin, preferably It is 10% by mass or more, more preferably 15% by mass or more. In addition, from the viewpoint of enhancing the repellent continuation effect, it is 40% by mass or less, preferably 30% by mass or less, and more preferably 25% by mass or less.

When the composition of the present invention contains the component (C), the mass ratio of the component (A) to the component (C) [(A)/(C)] is preferably from the viewpoint of enhancing the repellent effect 0.15 or more, more preferably 0.25 or more, and still more preferably 0.35 or more, from the viewpoint of ensuring the long-term storage stability of the composition, it is preferably 1.6 or less, more preferably 1.0 or less, still more preferably 0.8 or less, and still more Preferably, it is 0.6 or less. Therefore, the mass ratio [(A)/(C)] of the component (A) to the component (C) is preferably 0.15 to 1.6, more preferably 0.25 to 1.0, still more preferably 0.35 to 0.8, and still more preferably 0.35 ~0.6.

<Component (D): Tackifier> The composition of the present invention may further contain a tackifier as component (D). From the viewpoint of improving the repellent effect by adjusting the liquidity after application on the skin, the viewpoint of ensuring excellent spreadability on the skin by dispersing or dissolving the ingredients, and ensuring the long-term storage stability of the composition From the viewpoint of properties, the thickener is preferably one having moderate emulsification energy (ie, interfacial activity energy). In the present invention, an agent with emulsifying ability and thickening effect is used as a thickening agent. The component (D) includes: water-soluble cationic polymer, anionic polymer, nonionic polymer, amphoteric polymer or bipolar polymer, preferably containing anionic polymer and nonionic polymer One or more of the group consisting of anionic polymer, more preferably contains an anionic polymer and a nonionic polymer.

Specific examples of cationic polymers include: hydroxyethyl cellulose (polyquaternary ammonium salt-10) containing O-[2-hydroxy-3-(trimethylammonium)propyl] chloride group ), vinylpyrrolidone-dimethylaminomethyl ethyl methacrylate copolymer diethyl sulfate salt (polyquaternary ammonium salt-11), methylvinylimidazolium chloride-vinylpyrrolidone Copolymer etc.

Specific examples of the anionic polymer include: carboxyvinyl polymer, carboxymethyl cellulose, carrageenan, trixian gum, polystyrene sulfonate, agar, glycolic acid, karaya gum, pectin , Alginate, acrylic acid-alkyl methacrylate copolymer, (acrylic acid dimethyl taurate/methacrylic acid/ammonium methacrylate/dimethylacrylamide) copolymer, (sodium acrylate /Acrylic acid dimethyl taurate sodium) copolymer, polypropylene amide, (acrylic acid dimethyl taurate ammonium/vinylpyrrolidone) copolymer, (acrylate/acrylic acid alkyl (C10) -C30) ester) cross-linked polymer, (acrylic dimethyl taurate ammonium/beheneth-25 methacrylate) cross-linked polymer, (hydroxyethyl acrylate/acrylic dimethyl Sodium taurate) copolymer, (acrylamide/ammonium acrylate) copolymer, (sodium acrylate/acrylamide dimethyl taurine/dimethyl acrylamide) cross-linked polymer, polyacrylate- 13. Polyacrylate cross-linked polymer-6, alkali metal salt of poly(acrylic acid), hyaluronic acid or its alkali metal salt. From the viewpoint of ensuring excellent spreadability on the skin by dispersing or dissolving each component well, and the viewpoint of ensuring the long-term storage stability of the composition, the anionic polymer is preferably selected from (propylene Ammonium dimethyl taurate / methacrylic acid / ammonium methacrylate / dimethyl acrylamide) copolymer and ammonium dimethyl taurate / behenyl methacrylate-25 One or more of the group consisting of ester) cross-linked polymers.

Specific examples of nonionic polymers include cellulose ethers (hydroxybutyl methyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, ethyl hydroxyethyl cellulose, hydroxyethyl fiber (E.g.), propylene glycol alginate, poly(ethylene oxide), polyvinyl alcohol, polyvinylpyrrolidone, hydroxypropyl guar gum, locust bean gum, amylose, hydroxyethyl amylose , Starch and starch derivatives and mixtures of these. From the viewpoint of improving the repellent effect by adjusting the liquidity after being applied to the skin, cellulose ether is preferred.

As an amphoteric polymer or bipolar polymer, specifically, octylacrylamide/acrylate/butylaminoethyl methacrylate copolymer, polyquaternary ammonium salt-47, polyquaternary ammonium Salt-43 etc.

Component (D) can be used 1 type or in combination of 2 or more types. From the viewpoint of improving the persistence of the pest repellent effect by adjusting the liquidity after application on the skin, the viewpoint of ensuring excellent spreadability on the skin by dispersing or dissolving the ingredients, and ensuring the composition From the viewpoint of long-term storage stability, the component (D) is preferably one or more selected from the group consisting of anionic polymers and nonionic polymers, and is preferably selected from carboxyvinyl polymers , Acrylic acid-alkyl methacrylate copolymer, (acrylic acid ammonium dimethyl taurate/methacrylic acid/ammonium methacrylate/dimethylacrylamide) copolymer, (sodium acrylate/acrylic acid Sodium dimethyl taurate) copolymer, (acrylate/alkyl acrylate (C10-C30) ester) cross-linked polymer, (ammonium acrylate dimethyl taurate/behenyl methacrylate) -25 ester) cross-linked polymer and cellulose ether at least one of the group consisting of, more preferably selected from (acrylic acid dimethyl taurate ammonium/methacrylic acid/ammonium methacrylate/dimethyl Acrylamide) copolymer, (sodium acrylate/sodium acrylate dimethyl taurate) copolymer, (acrylate/alkyl acrylate (C10-C30) ester) cross-linked polymer and (acrylamide two One or more of the group consisting of ammonium methyl taurate/Beheneth-25 methacrylate) cross-linked polymer.

When an anionic polymer and a non-ionic polymer are contained as the component (D), the point of view is to improve the repellent effect, and the point of view that the components can be dispersed or dissolved well to ensure excellent spreadability on the skin , And from the viewpoint of ensuring the long-term storage stability of the composition of the present invention, it is preferably selected from the group consisting of (acrylic acid dimethyl taurate ammonium / methacrylic acid / ammonium methacrylate / dimethyl acrylic acid Amine) copolymer and ammonium acrylate dimethyl taurate/beheneth-25 methacrylate) cross-linked polymer consisting of one or more anionic polymers and non-ionic The cellulose ether of a high polymer is used together. When an anionic polymer and a non-ionic polymer are used together as the component (D), the mass ratio [anionic polymer/non-ionic polymer] will improve the repellent effect and make each component better From the viewpoint of ensuring excellent spreadability on the skin by dispersing or dissolving, and the viewpoint of ensuring the long-term storage stability of the composition, it is preferably 10/90 to 90/10, and more preferably 20/80 to 80 /20, more preferably 35/65 to 65/35.

As a commercially available product of the tackifier, for example, "CARBOPOL 980", "CARBOPOL 981", "CARBOPOL 1342", "CARBOPOL ETD2020", "PEMULEN TR-1", "PEMULEN TR-2" of Lubrizol Advanced Materials can be used , "Aculyn 22" of Dow Chemical Company, "Aristoflex AVC", "Aristoflex HMB", "Aristoflex Velvet", etc. manufactured by Clariant Iberica Production SA. Furthermore, the tackifier can also be formulated into a dispersion liquid dispersed through a dispersion medium.

Regarding the content of the component (D) in the composition of the present invention, from the viewpoint of enhancing the repellent effect, the viewpoint of ensuring excellent spreadability on the skin by dispersing or dissolving each component, and ensuring the composition From the viewpoint of long-term storage stability, it is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, still more preferably 0.1% by mass or more, and from the same viewpoint, it is preferably 5% by mass or less, more preferably 3 Mass% or less, more preferably 1 mass% or less. Furthermore, when the composition of the present invention contains a tackifier with interfacial activity, the content of other surfactants in the composition is preferably 1.5% by mass or less, more preferably 1% by mass or less.

＜Other ingredients＞ The composition of the present invention may appropriately contain ingredients other than the above, such as surfactants, preservatives, colorants, moisturizers, fragrances, pH adjusters, etc., within a range that does not impair the effects of the present invention. In addition, it may also contain medicinal or physiologically active ingredients such as vitamins, blood flow promoters, deactivated oxygen agents, anti-inflammatory agents, whitening agents, and fungicides. Furthermore, for example, the fragrance may be used as a bactericide or the like for other purposes.

The composition of the present invention can be manufactured by conventional methods. For example, it can manufacture by mixing components (A), (B) and other components used as needed, and stirring by a well-known apparatus.

The pests to be repelled by the composition of the present invention are not particularly limited and are more effective against flying pests. The so-called "flying pests" refer to pests that feed blood from the skin of animals such as people while flying, or that vector pathogenic bacteria and other pests while flying even if they do not suck blood, or pests that cause unpleasantness due to flying behavior. . Specific examples of flying pests include: Culex pipiens pallens, Culex tritaeniorhynchus, Culex pipiens molestus, Culex quinquefasciatus and other Culex mosquitoes, Aedes aegypti, Aedes albopictus, Anopheles sinensis, Aedes togoi, Anopheles gambiae, Anopheles stephensi) and other mosquitoes; Chironomus yoshimatsui, Tokunagayusurika akamusi, etc.; Twinnia japonensis Rubtsov, Yellow-footed gnat (Prosimulium yezoense), Greenwood gnat (Simulium aokii Takahasi) and other gnats; home Flies (Musca domestica), Muscina stabulans, Fannia canicularis, Calliphoridae, Sarcophagidae, Delia platura, Delia antiqua, Fruit flies (Tephritidae), fruit flies (Drosophilidae), butterfly flies (Psychodidae), tsetse flies (Glossinidae), sting flies (Stomoxys calcitrans) and other flies; ring flies, gadfly, blind flies, asperflies, etc.; Leptoconops nipponensis Tokunaga, Leptopsylla segnis, Culicoides arakawae (Culicoides arakawae) and other midges; yellow sparrow (Vespa simillima xanthoptera), dark yellow bee (Polistes jokahamae), honeybee (Apidae) and other bees. The composition of the present invention is particularly excellent in the repellent and sustained effect of the mosquitoes. Among the mosquitoes mentioned above, Culex pipiens pallens, Culex tristellate, Culex subterranean, Culex pipiens vulgaris, Aedes aegypti, and Aedes albopictus have excellent repellent and sustained effects.

[Methods of avoiding pests, methods of staying and restraining] The pest repellent method of the present invention is carried out by applying the pest repellent composition of the present invention on the surface of human skin. In addition, the pest retention inhibition method of the present invention prevents the pests from staying on human skin by attaching the pest retention inhibition composition of the present invention to the limbs of pests, especially flying pests. Hereinafter, these methods are also collectively referred to as "the method of the present invention".

Here, the so-called "smearing on the skin surface" not only refers to applying the composition directly to the skin surface by hand, but also includes applying the composition to the skin surface by spraying or the like. The amount of the composition applied on the skin surface is preferably 0.1 mg or more per 1 cm ² , more preferably 0.2 mg or more, and still more preferably 0.25 mg or more, from the viewpoint of enhancing the repellent effect. In addition, the upper limit of the smear amount is preferably 10 mg or less per 1 cm ^{2 from} the viewpoint of stickiness suppression and economic efficiency, more preferably 8 mg or less, and still more preferably 5 mg or less.

From the viewpoint of providing a repellent composition that is excellent in the continuous effect of repelling mosquitoes, is safe, suppresses unpleasant odors derived from the repellent ingredients, and has an excellent feeling of use, the composition of the present invention preferably contains the following components ( A) to (C), and the content of the pest repellent other than the component (A) and the component (B) is 15% by mass or less of an oil-in-water type mosquito repellent composition or a mosquito retention suppressing composition. (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass (B) selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass% (C) Water: 35 mass% or more and 86.995 mass% or less

From the standpoint of providing a repellent composition that is excellent in mosquito repelling effect, is safe, and suppresses unpleasant odors derived from the repellent ingredients, and has an excellent feeling of use, the composition of the present invention preferably contains the following components (A )～(C), the mass ratio of ingredient (A) to ingredient (C) [(A)/(C)] is 0.15 or more and 1.6 or less, and the content of pest repellent other than ingredient (A) and ingredient (B) is An oil-in-water type mosquito repellent composition or mosquito stay suppressing composition of 15 mass% or less. (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass (B) selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass% (C) Water: 35 mass% or more and 86.995 mass% or less

From the viewpoint of providing a repellent composition that is excellent in mosquito repellent effect, is safe, and suppresses the unpleasant odor derived from the repellent ingredient, and has an excellent feeling of use, the composition of the present invention preferably contains the following components (A )～(C), the mass ratio of component (A) to component (B) [(A)/(B)] is 7 or more and 3000 or less, the mass ratio of component (A) to component (C) [(A)/ (C)] An oil-in-water type mosquito repellent composition or mosquito stay suppressing composition with a content of 0.15 or more and 1.6 or less, and a pest repellent other than component (A) and component (B) of 15 mass% or less. (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass% (C) Water: 35 mass% or more and 86.995 mass% or less

From the viewpoint of providing a repellent composition that is excellent in the continuous effect of repelling mosquitoes, is safe, suppresses unpleasant odors derived from the repellent ingredients, and has an excellent feeling of use, the composition of the present invention preferably contains the following components ( A)～(D), the mass ratio of component (A) to component (B) [(A)/(B)] is 7 or more and 3000 or less, the mass ratio of component (A) to component (C) [(A) /(C)] is 0.15 or more and 1.6 or less, and the content of pest repellents other than component (A) and component (B) is 15% by mass or less of an oil-in-water mosquito repellent composition or mosquito retention inhibitor composition. (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil and hydrocarbon oil. One or more non-volatile liquid oily ingredients in the group: 13% by mass to 50% by mass (B) selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass% (C) Water: 35 mass% or more and 86.995 mass% or less (D) Tackifier: 0.05 mass% to 5 mass%

The method for repelling pests of the present invention is a method of avoiding pests even if mosquitoes and other pests land on the object coated with or attached to the composition of the present invention, the pests will not stay in place, and specifically, have the following Stay-inhibiting effect: after mosquitoes and other pests land on the skin of humans and other animals, they are not allowed to stay on the surface of the animal's skin to the extent that a needle can be inserted, specifically, for example, more than 1 second. This effect is based on the previously unseen principle of avoidance of pests, and is relatively safe, without side effects such as skin cracking.

Regarding the above-mentioned embodiments, the present invention further discloses the following embodiments. ＜1＞ An oil-in-water type pest repellent composition or pest staying suppression composition, which contains the following components (A) and (B), and the mass ratio of component (A) to component (B) [(A)/(B)] Is above 7 and below 3000, (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 99.995% by mass; (B) selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass%. ＜2＞ The composition as described in <1>, wherein the mass ratio of component (A) to component (B) [(A)/(B)] is 13 or more, preferably 25 or more, and preferably 300 or less, more preferably It is 100 or less, more preferably 50 or less. ＜3＞ The composition as described in any one of <1> to <3>, wherein the content of the existing pest repellent other than component (B) is 15% by mass or less, preferably 10% by mass or less, more preferably 5% by mass % Or less, more preferably 4% by mass or less, still more preferably 3% by mass or less, and still more preferably 1% by mass or less. ＜4＞ For the composition described in <3>, the existing pest repellent other than component (B) is citronella oil. ＜5＞ The composition according to any one of <1> to <4>, wherein the surface tension of component (A) at 25°C is 15 mN/m or more, preferably 17 mN/m or more, and 30 mN/ m or less, preferably 28 mN/m or less, more preferably 25 mN/m or less, still more preferably 23 mN/m or less, and still more preferably 21 mN/m or less. ＜6＞ Such as the composition described in any one of <1> to <5>, wherein the viscosity of component (A) measured by a B-shaped rotary viscometer at 23°C is 1 mPa·s or more and 300 mPa·s or less, It is preferably 210 mPa·s or less, more preferably 100 mPa·s or less, still more preferably 60 mPa·s or less, still more preferably 40 mPa·s or less, and even more preferably 30 mPa·s or less. ＜7＞ The composition according to any one of <1> to <6>, wherein component (A) is one or more selected from the group consisting of silicone oil, ester oil, ether oil and hydrocarbon oil, preferably One or more selected from the group consisting of silicone oil, ester oil, and hydrocarbon oil, more preferably one or more selected from the group consisting of silicone oil and ester oil, and more preferably polysilicone Silicone oil. ＜8＞ The composition as described in any one of <1> to <7>, wherein the content of component (A) is 20% by mass or more, preferably 25% by mass or more, and 80% by mass or less, preferably 50% by mass % Or less, more preferably 40% by mass or less, and still more preferably 35% by mass or less. ＜9＞ The composition described in any one of <1> to <8>, wherein component (B) is selected from N,N-diethyltoluamide and 2-(2-hydroxyethyl)-1-piperidine One or more of the group consisting of 1-methylpropyl carboxylate. ＜10＞ The composition as described in any one of <1> to <9>, wherein the content of component (B) is 0.01% by mass or more, preferably 0.05% by mass or more, more preferably 0.1% by mass or more, and still more preferably 0.5% by mass or more, more preferably 0.8% by mass or more, and 2.5% by mass or less, preferably 2.2% by mass or less, more preferably 2% by mass or less, still more preferably 1.8% by mass or less, and still more preferably 1.5% by mass or less.

＜11＞ The composition as described in any one of <1> to <10>, which contains water as a component (C). ＜12＞ The composition as described in <11>, wherein the content of component (C) is 5% by mass or more, preferably 10% by mass or more, more preferably 35% by mass or more, still more preferably 50% by mass or more, and 86.995 % By mass or less, preferably 85% by mass or less, more preferably 80% by mass or less, and still more preferably 75% by mass or less. ＜13＞ The composition as described in <11> or <12> is an oil-in-water type composition. The content of component (C) in the composition is preferably 35% by mass or more, more preferably 40% by mass or more, and more It is preferably 45% by mass or more, more preferably 86.995% by mass or less, more preferably 80% by mass or less, and more preferably 75% by mass or less. ＜14＞ The composition as described in <11> or <12>, which is a water-in-oil type composition, the content of component (C) in the composition is preferably 5% by mass or more, more preferably 10% by mass or more, and It is preferably 15% by mass or more, more preferably 40% by mass or less, more preferably 30% by mass or less, and still more preferably 25% by mass or less. ＜15＞ The composition described in any one of <11> to <14>, wherein the mass ratio of component (A) to component (C) [(A)/(C)] is 0.15 or more, preferably 0.25 or more, more It is preferably 0.35 or more and 1.6 or less, preferably 1.0 or less, more preferably 0.8 or less, and still more preferably 0.6 or less. ＜16＞ The composition as described in any one of <1> to <15>, which further contains preferably 0.01% by mass or more, more preferably 0.05% by mass or more, still more preferably 0.1% by mass or more, and preferably 5 Mass% or less, more preferably 3 mass% or less, and still more preferably 1 mass% or less thickening agent as component (D). ＜17＞ The composition described in <16>, which contains at least one selected from the group consisting of water-soluble cationic polymers, anionic polymers, nonionic polymers, and amphoteric polymers or bipolar polymers The component (D) is preferably at least one selected from the group consisting of an anionic polymer and a nonionic polymer, and more preferably an anionic polymer and a nonionic polymer. ＜18＞ The composition as described in <17>, which contains selected from the group consisting of carboxyvinyl polymer, carboxymethyl cellulose, carrageenan, trixian gum, polystyrene sulfonate, agar, glycoside, karaya, pectin , Alginate, acrylic acid-alkyl methacrylate copolymer, (acrylic acid dimethyl taurate/methacrylic acid/ammonium methacrylate/dimethylacrylamide) copolymer, (sodium acrylate /Acrylic acid dimethyl taurate sodium) copolymer, polypropylene amide, (acrylic acid dimethyl taurate ammonium/vinylpyrrolidone) copolymer, (acrylate/acrylic acid alkyl (C10) -C30) ester) cross-linked polymer, (acrylic dimethyl taurate ammonium/beheneth-25 methacrylate) cross-linked polymer, (hydroxyethyl acrylate/acrylic dimethyl Sodium taurate) copolymer, (acrylamide/ammonium acrylate) copolymer, (sodium acrylate/acrylamide dimethyl taurine/dimethyl acrylamide) cross-linked polymer, polyacrylate- 13. Polyacrylate cross-linked polymer-6, poly(acrylic acid) alkali metal salt, hyaluronic acid or alkali metal salt thereof, as an anionic polymer, preferably selected from the group consisting of (acrylic acid) Ammonium dimethyl taurate/methacrylic acid/ammonium methacrylate/dimethyl acrylamide) copolymer and ammonium acrylate dimethyl taurate/behenyl methacrylate-25 ester ) One or more of the group of cross-linked polymers. ＜19＞ The composition as described in <17> or <18>, which contains cellulose ether (selected from hydroxybutyl methyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, ethyl hydroxyethyl cellulose) And one or more of the group consisting of hydroxyethyl cellulose), propylene glycol alginate, poly(ethylene oxide), polyvinyl alcohol, polyvinylpyrrolidone, hydroxypropyl guar gum, acacia One or more of the group consisting of soybean gum, amylose, hydroxyethyl amylose, starch and starch derivatives, and mixtures thereof, as a nonionic polymer, preferably contains cellulose ether. ＜20＞ The composition described in any one of <16> to <19> preferably contains a composition selected from (acrylic acid dimethyl taurate ammonium / methacrylic acid / ammonium methacrylate / dimethyl acrylic acid Amine) copolymer and ammonium acrylate dimethyl taurate/beheneth-25 methacrylate) cross-linked polymer consisting of one or more anionic polymers and non-ionic The cellulose ether of a high molecular weight is used as component (D). ＜21＞ The composition as described in any one of <16> to <20>, which contains an anionic polymer and a nonionic polymer as component (D), and the mass ratio [anionic polymer/nonionic polymer] It is preferably 10/90 to 90/10, more preferably 20/80 to 80/20, and still more preferably 35/65 to 65/35. ＜22＞ An oil-in-water type mosquito repellent composition or mosquito retention inhibitor composition, which contains the following components (A) to (C), and the content of pest repellents other than component (A) and component (B) is 15% by mass or less , (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass; (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.01% by mass to 3% by mass; (C) Water: 35 mass% or more and 86.995 mass% or less. ＜23＞ An oil-in-water type mosquito repellent composition or mosquito retention inhibitor composition, which contains the following components (A) to (C), the mass ratio of component (A) to component (C) [(A)/(C)] 0.15 or more and 1.6 or less, and the content of pest repellents other than ingredient (A) and ingredient (B) is 15% by mass or less, (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass; (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass%; (C) Water: 35 mass% or more and 86.995 mass% or less. ＜24＞ An oil-in-water type mosquito repellent composition or mosquito retention inhibitor composition, which contains the following components (A) to (C), the mass ratio of component (A) to component (B) [(A)/(B)] Is 7 or more and 3000 or less, the mass ratio of ingredient (A) to ingredient (C) [(A)/(C)] is 0.15 or more and 1.6 or less, and the content of pest repellent other than ingredient (A) and ingredient (B) is 15% by mass or less, (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 50% by mass; (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass%; (C) Water: 35 mass% or more and 86.995 mass% or less. ＜25＞ An oil-in-water type mosquito repellent composition or mosquito retention inhibitor composition, which contains the following components (A) to (D), the mass ratio of component (A) to component (B) [(A)/(B)] Is 7 or more and 3000 or less, the mass ratio of ingredient (A) to ingredient (C) [(A)/(C)] is 0.15 or more and 1.6 or less, and the content of pest repellent other than ingredient (A) and ingredient (B) is 15% by mass or less, (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil and hydrocarbon oil One or more non-volatile liquid oily components in the group: 13% by mass to 50% by mass; (B) Selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group One or more repellent ingredients in the group consisting of ethyl propionate and p-menthane-3,8-diol: 0.005 mass% to 3 mass%; (C) Water: 35 mass% or more and 86.995 mass% or less; (D) Tackifier: 0.05% by mass to 5% by mass. ＜26＞ The composition as described in <25>, wherein component (D) contains selected from (acrylic acid dimethyl taurate ammonium/methacrylic acid/ammonium methacrylate/dimethyl acrylamide) copolymer and acrylic acid Dimethyl ammonium taurate/Beheneth-25 methacrylate) cross-linked polymer consisting of one or more anionic polymers and cellulose ethers as nonionic polymers , And the mass ratio [anionic polymer/nonionic polymer] is 10/90 to 90/10. ＜27＞ A method for repelling pests is to apply the composition described in any one of <1> to <26> on the surface of human skin. ＜28＞ A method for inhibiting the staying of pests, which prevents the pests from staying on human skin by attaching the composition described in any one of <1> to <26> to the limbs of the pests. [Example]

Hereinafter, the present invention will be explained through examples, but the present invention is not limited to the scope of the examples. In addition, in this example, various measurements and evaluations were performed by the following methods.

(Surface tension of liquid oily ingredients) The surface tension of the liquid oily component is measured using an automatic surface tensiometer "Tensiometer K100" (KRUSS company) by the Wilhelmy method using a platinum plate at 25°C.

(Viscosity of liquid oily ingredients) As a B-shaped rotational viscometer based on JIS K7117-1: 1999, Toki Industry Co., Ltd. "Viscometer TVB-10" is used. The components to be measured differ greatly in viscosity values of each sample, so it is difficult to accurately measure all of them under one measurement condition. Therefore, two types of rotors were used for measurement. First, rotor M2 was used to measure the viscosity at a speed of 12 rpm at 23°C. At this time, for components with a viscosity of 2500 mPa·s or more, measure again at 6 rpm to obtain the viscosity value. On the other hand, for components with a viscosity of 20 mPa·s or less, use an L adapter (Adapter) as a low-viscosity rotor, and set the rotation speed to 30 rpm under an environment of 23°C to obtain the viscosity value.

(Evaluation of the continuous effect of repelling pests) (I) Preparation for Aedes albopictus Aedes albopictus uses the Aedes albopictus eggs provided by Sumitomo Techno Service Co., Ltd. to grow into adults by raising them in a cage at 27°C and a relative humidity (RH) of 60%. Put about 1 cm of water in a transparent plastic dish, and put in the filter paper that lays the purchased eggs, so that the eggs hatch into pupae. Thereafter, the hatched pupae were fed with bait for tropical fish (TetraMin) as bait for larvae every day. After 1 week, use a dropper to collect the pupae, transfer them to a 20 mL plastic cup, and transfer them to a cage covered with nets. For pupae, 10% by mass sucrose as bait for adults was put into a 25 mL plastic tube and fed. After emergence, the male and female mosquitoes were raised in the same cage for 5 days for mating. After 5 days of feeding, the adults were collected using a fluke tube and anesthetized on ice for 5 minutes. The male and female mosquitoes were visually distinguished, and only the female mosquitoes were recovered for evaluation.

(II) Determination of the duration of the repellent effect About 100 female Aedes albopictus were moved into a plastic cage (30×30×30 cm), and the test was carried out at 27°C and relative humidity (RH) 60%. A hole with a size of 4×5 cm was made on the arm of a rubber glove of the size of the subject's arm, and the composition of each example was evenly applied at 2 mg/cm ² . Afterwards, in order to rejuvenate Aedes albopictus, blow air into the plastic cage for 5 seconds. The test was carried out by extending the front arm into the plastic cage immediately after applying the composition, thereby exposing it to Aedes albopictus for 2 minutes, and counting the number of stays. The time point when there are 2 stays in total is regarded as the end of the test, and the exposure is carried out for 2 minutes every 30 minutes before the end of the test. If there is a second stay during the 30th minute exposure, the duration of the repellent effect will be judged as 0 minutes, and if there is a second stay during the 60th minute exposure, the duration of the repellent effect will be judged For 30 minutes. The test was conducted by 3 subjects, and the average duration of the repellent effect was calculated.

(Evaluation of Odor Intensity) The test product was applied to the 4.5×4.5 cm surface of the inner forearm of a human to become 2 mg/cm ² . Immediately thereafter, 3 evaluators performed sensory evaluation to determine the strength. The odor intensity is divided into 6 evaluation stages (5: strong odor, 4: strong odor, 3: easily perceivable odor, 2: weaker odor with a certain odor, 1: barely perceivable The odor, 0: no odor) was evaluated, and the average value of the evaluations of the 3 evaluators was taken as the odor intensity. The odor intensity suitable for skin application is classified as follows. The smaller the value, the better the composition. A: 2.5 or less B: more than 2.5 and less than 3.5 C: more than 3.5

(Evaluation of long-term storage stability) Put 80 mL of the composition of each example into a 100 mL glass bottle and seal it. After storing at 50°C for 1 month, visually confirm whether there is oily phase separation in the composition, and indicate it according to the following criteria. A: No change. B: The oil phase is unified, but a small amount of self-emulsion oozes to the surface. C: Oil phase separation is seen.

Examples 1 to 38, Comparative Examples 1 to 11 (Production and Evaluation of Compositions) Mix the ingredients shown in Table 1 according to the mixing amounts shown in Tables 2-8, and use the one that replaces the mixing section of TKROBOMIX (Special Machinery & Chemical Industry Co., Ltd.) with TKHomo-Mixer MARKII2.5 at 8,000 rpm Stir for 2 minutes. After this step, the oil-in-water type composition of each example is obtained. The notation of (A)～(D) in the table corresponds to the components (A)～(D) in this specification, and the notation of (a) corresponds to the range of component (A) in this specification. Liquid oily ingredients. In addition, the compounding amounts described in Tables 2 to 8 are the effective ingredient amounts (mass %) of each component. Using the obtained composition, various evaluations were performed by the above-mentioned methods. The results are shown in Tables 2-8.

[Table 1] Table 1 Product name Ingredient name Manufacturer name 25℃ surface tension [mN/m] Viscosity at 23℃ [mPa・s] (A1) Silicone KF-96Α-6cs Dimethyl polysiloxane Shin-Etsu Chemical Industry Co., Ltd. 19.0 5 (A2) Silicone KF-96Α-10cs Dimethyl polysiloxane Shin-Etsu Chemical Industry Co., Ltd. 21.0 10 (A3) Silicone KF-96Α-50cs Dimethyl polysiloxane Shin-Etsu Chemical Industry Co., Ltd. 21.0 60 (A4) Silicone KF-96Α-200cs Dimethyl polysiloxane Shin-Etsu Chemical Industry Co., Ltd. 21.0 210 (A5) EXCEPARL IPM Isopropyl myristate Kao Corporation 28.0 5 (A6) NIKKOL Squalane Squalane Nippon Surfactant Industries Co., Ltd. 30.0 42 (A7) ASE-166K Cetyl-1,3-dimethyl butyl ether Kao Corporation 28.0 7 (A8) Polypropylene glycol 1,3-butylene glycol Polypropylene glycol/1,3-butanediol (mixture of mass ratio 3/7) Fujifilm Wako Pure Chemical Co., Ltd. 34.0 160 (a1) Silicone KF-96-500cs Dimethyl polysiloxane Shin-Etsu Chemical Industry Co., Ltd. 21.0 560 (a2) ZEMEA PROPANEDIOL Propylene Glycol DuPont Tate & Lyle Bio Products, LLC 48.0 53 (a3) glycerine glycerin Fujifilm Wako Pure Chemical Co., Ltd. 65.0 950 (a4) Silicone KF-96-5000cs Dimethyl polysiloxane Shin-Etsu Chemical Industry Co., Ltd. 21.0 4500 (B1) DEET N,N-Diethyltoluamide Tokyo Chemical Industry Co., Ltd. - - (B2) Ecarudin 2-(2-Hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester Combi-Blocks - - (B3) IR3535 Ethyl 3-(acetylbutyl)aminopropionate Fluorochem Ltd. - - (B4) p-Menthane-3,8-diol P-menthane-3,8-diol Tronto Research Chemicals - - (D1) Aristoflex HMB (Ammonium acrylate dimethyl taurate/Beheneth-25 methacrylate) cross-linked polymer Clariant Iberica Production SA - - (D2) PEMULEN TR-1 (Acrylate/Acrylate alkyl (C10-C30) ester) crosslinked polymer Lubrizol Advanced Materials, Inc. - - (D3) PEMULEN TR-2 (Acrylate/Acrylate alkyl (C10-C30) ester) crosslinked polymer Lubrizol Advanced Materials, Inc. - -

[Table 2] Table 2 Example Comparative example 1 2 3 4 1 (A1) Silicone KF-96Α-6cs Dimethyl polysiloxane 30.00 30.00 30.00 30.00 30.00 (B1) DEET N,N-Diethyltoluamide 2.00 - - - - (B2) Ecarudin 2-(2-Hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester - 2.00 - - - (B3) IR3535 Ethyl 3-(acetylbutyl)aminopropionate - - 2.00 - - (B4) p-Menthane-3,8-diol P-menthane-3,8-diol - - - 2.00 - (D1) Aristoflex HMB (Ammonium acrylate dimethyl taurate/Beheneth-25 methacrylate) cross-linked polymer 0.50 0.50 0.50 0.50 0.50 (C) Ion exchange water 67.50 67.50 67.50 67.50 69.50 total 100.00 100.00 100.00 100.00 100.00 Mass ratio (A)/(B) 15 15 15 15 - Mass ratio (A)/(C) 0.44 0.44 0.44 0.44 0.43 Evaluation results Duration of avoidance effect (min) 360 360 300 300 90 Odor intensity Score 3.0 2.7 2.7 3.3 0.7 determination B B B B A Long-term storage stability determination A - - A -

[table 3] table 3 Example Comparative example 1 5 6 7 1 2 3 4 (A1) Silicone KF-96Α-6cs Dimethyl polysiloxane 30.00 30.00 30.00 30.00 30.00 30.00 - - (B1) DEET N,N-Diethyltoluamide 2.00 1.00 0.10 0.01 - 4.00 2.00 4.00 (D1) Aristoflex HMB (Ammonium acrylate dimethyl taurate/Beheneth-25 methacrylate) cross-linked polymer 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 (C) Ion exchange water 67.50 68.50 69.40 69.49 69.50 65.50 97.50 95.50 total 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 Mass ratio (A)/(B) 15 30 300 3000 - 7.5 - - Mass ratio (A)/(C) 0.44 0.44 0.43 0.43 0.43 0.46 - - Evaluation results Duration of avoidance effect (min) 360 300 180 150 90 450 90 180 Odor intensity Score 3.0 2.3 1.3 1.0 0.7 3.7 3.0 3.7 determination B A A A A C B C Long-term storage stability determination A A A A - - - -

[Table 4] Table 4 Example 1 8 9 10 11 12 13 14 15 16 17 18 19 20 twenty one (A1) Silicone KF-96Α-6cs Dimethyl polysiloxane 30.00 15.00 45.00 - - - - - - - - - - - - (A2) Silicone KF-96Α-10cs Dimethyl polysiloxane - - - - - - - - - - - - - - - (A3) Silicone KF-96Α-50cs Dimethyl polysiloxane - - - 30.00 15.00 45.00 - - - - - - - - - (A4) Silicone KF-96Α-200cs Dimethyl polysiloxane - - - - - - 30.00 15.00 45.00 - - - - - - (A5) EXCEPARL IPM Isopropyl myristate - - - - - - - - - 30.00 15.00 45.00 - - - (A6) NIKKOL Squalane Squalane - - - - - - - - - - - - 30.00 15.00 45.00 (B1) DEET N,N-Diethyltoluamide 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 (D1) Aristoflex HMB (Ammonium acrylate dimethyl taurate/Beheneth-25 methacrylate) cross-linked polymer 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 (C) Ion exchange water 67.50 82.50 52.50 67.50 82.50 52.50 67.50 82.50 52.50 67.50 82.50 52.50 67.50 82.50 52.50 total 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 Mass ratio (A)/(B) 15 7.5 22.5 15.0 7.5 22.5 15.0 7.5 22.5 15 7.5 22.5 15 7.5 22.5 Mass ratio (A)/(C) 0.44 0.18 0.86 0.44 0.18 0.86 0.44 0.18 0.86 - 0.18 0.86 - 0.18 0.86 Evaluation results Duration of avoidance effect (min) 360 240 450 330 150 420 180 120 330 240 120 330 210 120 330 Odor intensity Score 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.7 2.7 2.7 determination B B B B B B B B B B B B B B B Long-term storage stability determination A A B A A B A A B A A B A A B

[table 5] table 5 Example twenty two twenty three twenty four 25 26 27 28 29 30 31 (A1) Silicone KF-96Α-6cs Dimethyl polysiloxane - - - - - - 15.00 15.00 - 60.00 (A2) Silicone KF-96Α-10cs Dimethyl polysiloxane - - - - - - - - - - (A5) EXCEPARL IPM Isopropyl myristate - - - - - - 15.00 - 15.00 - (A6) NIKKOL Squalane Squalane - - - - - - - 15.00 15.00 - (A7) ASE-166K Cetyl-1,3-dimethyl butyl ether 30.00 15.00 45.00 - - - - - - - (A8) Polypropylene glycol 1,3-butylene glycol Polypropylene glycol/1,3-butanediol (mixture of mass ratio 3/7) - - - 30.00 15.00 45.00 - - - - (B1) DEET N,N-Diethyltoluamide 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 (D1) Aristoflex HMB (Ammonium acrylate dimethyl taurate/Beheneth-25 methacrylate) cross-linked polymer 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 (C) Ion exchange water 67.50 82.50 52.50 67.50 82.50 52.50 67.50 67.50 67.50 37.50 total 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 Mass ratio (A)/(B) 15.0 7.5 22.5 15.0 7.5 22.5 15 15 15 30 Mass ratio (A)/(C) 0.44 0.18 0.86 0.44 0.18 0.86 0.44 0.44 0.44 1.60 Evaluation results Duration of avoidance effect (min) 180 120 330 180 120 270 330 300 240 600 Odor intensity Score 2.7 2.7 2.7 2.7 2.7 2.7 3.0 2.7 2.7 3.0 determination B B B B B B B B B B Long-term storage stability determination A B B A B B B B B C

[Table 6] Table 6 Comparative example 1 3 5 6 7 8 9 (A1) Silicone KF-96Α-6cs Dimethyl polysiloxane 30.00 - 10.00 - - - - (A5) EXCEPARL IPM Isopropyl myristate - - - - - - - (A6) NIKKOL Squalane Squalane - - - - - - - (a1) Silicone KF-96-500cs Dimethyl polysiloxane - - - 30.00 - - - (a2) ZEMEA PROPANEDIOL Propylene Glycol - - - - 30.00 - - (a3) glycerine glycerin - - - - - 30.00 - (a4) Silicone KF-96-5000cs Dimethyl polysiloxane - - - - - - 30.00 (B1) DEET N,N-Diethyltoluamide - 2.00 2.00 2.00 2.00 2.00 2.00 (D1) Aristoflex HMB (Ammonium acrylate dimethyl taurate/Beheneth-25 methacrylate) cross-linked polymer 0.50 0.50 0.50 0.50 0.50 0.50 0.50 (C) Ion exchange water 69.50 97.50 87.50 67.50 67.50 67.50 67.50 total 100.00 100.00 100.00 100.00 100.00 100.00 100.00 Mass ratio (A)/(B) - 0.00 5.0 0.00 0.00 0.00 0.00 Mass ratio (A)/(C) 0.43 0.00 0.11 0.00 0.00 0.00 0.00 Evaluation results Duration of avoidance effect (min) 90 90 90 90 90 90 90 Odor intensity Score 0.7 3.0 3.0 3.0 2.7 2.3 3.0 determination A B B B B B B Long-term storage stability determination - - - - - - -

[Table 7] Table 7 Example 1 32 33 34 (A1) Silicone KF-96Α-6cs Dimethyl polysiloxane 30.00 30.00 30.00 30.00 (B1) DEET N,N-Diethyltoluamide 2.00 2.00 2.00 2.00 (D1) Aristoflex HMB (Ammonium acrylate dimethyl taurate/Beheneth-25 methacrylate) cross-linked polymer 0.50 - - - (D2) PEMULEN TR-1 (Acrylate/Acrylate alkyl (C10-C30) ester) crosslinked polymer - 0.50 - - (D3) PEMULEN TR-2 (Acrylate/Acrylate alkyl (C10-C30) ester) crosslinked polymer - - 0.50 - (C) Ion exchange water 67.50 67.50 67.50 68.00 total 100.00 100.00 100.00 100.00 Mass ratio (A)/(B) 15 15 15 15 Mass ratio (A)/(C) 0.44 0.44 0.44 0.44 Evaluation results Duration of avoidance effect (min) 360 360 360 360 Odor intensity Score 3.0 3.0 3.0 3.0 determination B B B B Long-term storage stability determination A - - -

[Table 8] Table 8 Example Comparative example 35 36 37 38 1 10 11 (A1) Silicone KF-96Α-6cs Dimethyl polysiloxane 30.00 30.00 30.00 30.00 30.00 - - (B4) p-Menthane-3,8-diol P-menthane-3,8-diol 2.00 1.00 0.10 0.01 - 2.00 4.00 (D1) Aristoflex HMB (Ammonium acrylate dimethyl taurate/Beheneth-25 methacrylate) cross-linked polymer 0.50 0.50 0.50 0.50 0.50 0.50 0.50 (C) Ion exchange water 67.50 68.50 69.40 69.49 69.50 97.50 95.50 total 100.00 100.00 100.00 100.00 100.00 100.00 100.00 Mass ratio (A)/(B) 15 30 300 3000 - - - Mass ratio (A)/(C) 0.44 0.44 0.43 0.43 0.43 - - Evaluation results Duration of avoidance effect (min) 300 240 180 150 90 90 150 Odor intensity Score 3.3 3.0 2.7 2.0 0.7 3.3 4.0 determination B B A A A B C Long-term storage stability determination A A A A - A C

According to Tables 2 to 8, it can be seen that the pest repellent time of the composition of the present invention (Examples 1 to 38) containing specific amounts of components (A) and (B) lasts for more than 2 hours, and the repelling effect is excellent, and the inhibition comes from Avoid the unpleasant smell of the ingredients. [Industrial availability]

According to the present invention, it is possible to provide a pest repellent composition and a pest stay inhibiting composition that have excellent repellent effects on pests, especially flying pests, are safe, have less unpleasant odors derived from the repellent ingredients, and are suitable for skin application. , Pest avoidance method, and pest stay control method.

Claims (5)

A pest repellent composition, which contains the following components (A) and (B): (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 99.995% by mass; (B) selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group Ethyl propionate and one or more repellent ingredients in the group consisting of p-menthane-3,8-diol: 0.005 mass% to 3 mass%. A pest staying inhibitory composition, which contains the following components (A) and (B): (A) The surface tension at 25°C is 40 mN/m or less, and the viscosity at 23°C measured by the B-shaped rotary viscometer is 400 mPa·s or less, selected from silicone oil, ester oil, ether oil, and hydrocarbon oil , One or more non-volatile liquid oily components in the group consisting of aliphatic alcohols and polyols: 13% by mass to 99.995% by mass; (B) selected from N,N-diethyltoluamide, 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester, 3-(acetylbutyl)amino group Ethyl propionate and one or more repellent ingredients in the group consisting of p-menthane-3,8-diol: 0.005 mass% to 3 mass%. The composition of claim 1 or 2, wherein component (A) is one or more selected from the group consisting of silicone oil, ester oil and hydrocarbon oil. A method for avoiding pests, which is to apply the composition of claim 1 to the surface of human skin. A method for inhibiting the staying of pests, which prevents pests from staying on human skin by attaching the composition of claim 2 to the limbs of the pests.