TW201934080A - Physiological signal correction device, correction method, and wearable device with correction function - Google Patents

Abstract

A physiological signal correction device, a correction method, and a wearable device with a correction function for the physiological signal are provided. The physiological signal correction device includes a physiological signal sensor, a warping sensor and a signal processing device. The physiological signal sensor is attached to an object to be measured to obtain a physiological signal value from a sensing electrode. The warping sensor is disposed on the physiological signal sensor, and detects whether a warping condition of the physiological signal sensor with respect to the object to be measured occurs. The signal processing device corrects the physiological signal value provided by the physiological signal sensor according to the warping condition provided by the warping sensor. The warping situation is occurred by a distance between a part of the sensing electrode and the object to be measured or a change of a contact area between a part of the sensing electrode and the object to be measured.

Description

Physiological signal correction device, correction method and wearable device with correction function

The embodiment of the present invention relates to a signal detection and processing technology, and relates to a physiological signal correction device, a physiological signal correction method, and a wearable device with a physiological signal correction function.

In terms of wearable biomedical measurement technology, physiological signal measuring devices (such as sensing electrode patches or sensors) can be worn on the body, and various physiological signals of the wearer can be recorded at any time in a non-invasive manner, thereby Learn the wearer's body temperature, pulse, heartbeat, breathing frequency, etc. In addition, it can also remind or prevent possible physiological abnormalities, and even quickly remind and ask for help when symptoms occur. Therefore, wearable biomedical measurement technology is a very convenient technological advancement for wearers such as patients who are nursing at home, patients with a history of heart disease, or elderly people living alone.

However, based on the limitations of the prior art, the sensing electrode patches that need to be tightly attached to the wearer's skin often warp, fall off, etc., resulting in user experience that still needs to be improved. In detail, general physiological signal measurement devices (such as sensing electrode patches or sensors) usually need to be closely attached to the skin of the wearer to obtain accurate physiological signals. However, due to the sweat generated by the wearer's skin, The pulling or other factors caused by the movement may cause part or the whole of the sensing electrode patch to fall off, fail to adhere to the skin, etc., causing the measured physiological signal to be distorted. The solution of the prior art is usually to enhance the adhesion of the sensing electrode patch to enhance the adhesion to the skin, but it usually makes the wearer more uncomfortable, still has concerns about falling off, or makes the sensing electrode patch Setting is more inconvenient. In addition, in many cases, the wearer does not know that the sensing electrode patch has come off and the physiological signal is distorted, resulting in poor accuracy of the physiological signal.

Embodiments of the present invention provide a physiological signal correction device, a physiological signal correction method, and a wearable device with a physiological signal correction function, which can detect and feedback the mutual relationship between a sensing electrode and a test object (such as a user's skin). The warped condition is separated, and the physiological signal is compensated and corrected according to the warped condition, so that the physiological signal measured by the embodiment of the present invention has high accuracy.

The physiological signal correction device according to the embodiment of the present invention includes a physiological signal sensor, a warp sensor, and a signal processing device. The physiological signal sensor includes a sensing electrode. The physiological signal sensor is attached to the object under test to obtain a physiological signal value from the sensing electrode. The warpage sensor is disposed on the physiological signal sensor. The warping sensor detects whether a warping situation of the physiological signal sensor relative to the object to be tested occurs. The signal processing device is coupled to the physiological signal sensor and the warpage sensor. The signal processing device corrects the physiological signal value provided by the physiological signal sensor according to the warping situation provided by the warping sensor, wherein the warping situation is determined by a distance between a part of the sensing electrode and the object to be measured or It is caused by a change in the contact area between a part of the sensing electrode and the object to be measured.

The method for correcting a physiological signal according to the embodiment of the present invention is applicable to a physiological signal correction device including a physiological signal sensor and a warpage sensor. The warpage sensor is disposed on the physiological signal sensor. The calibration method includes the following steps: when the physiological signal sensor is attached to the object to be measured, obtaining a physiological signal value from the physiological signal sensor. Detect whether a warping situation of the physiological signal sensor relative to the object to be tested occurs through the warping sensor, wherein the warping situation is caused by a distance between a part of the physiological signal sensor and the object to be tested or It is generated by a change in the contact area between a part of the sensing electrode and the object to be measured. And, the physiological signal value provided by the physiological signal sensor is corrected according to the warping situation provided by the warpage sensor.

The wearable device with a correction function according to the embodiment of the present invention includes a physiological signal sensor, a warp sensor, and a signal processing device. The physiological signal sensor includes a sensing electrode. The physiological signal sensor is attached to the object under test to obtain a physiological signal value from the sensing electrode. The warpage sensor is disposed on the physiological signal sensor. The warping sensor detects whether a warping situation of the physiological signal sensor relative to the object to be tested occurs. The signal processing device is coupled to the physiological signal sensor and the warpage sensor. The signal processing device corrects the physiological signal value provided by the physiological signal sensor according to the warping situation provided by the warping sensor, wherein the warping situation is determined by a distance between a part of the sensing electrode and the object to be measured or It is caused by a change in the contact area between a part of the sensing electrode and the object to be measured.

Based on the above, the physiological signal correction device and the wearable device according to the embodiments of the present invention use the warpage sensor disposed on the physiological signal sensor to detect the sensing electrode and the object to be measured in the physiological signal sensor. (Such as the user's skin), and correct physiological signals based on the warpage. In other words, in the embodiment of the present invention, one or more warpage sensors are configured on a physiological signal sensor (such as a sensing electrode patch) to detect and feedback the separation between the sensing electrode and the object to be tested. Area percentage value, and use the area percentage value to query the correction database to compensate or correct the missing part of the physiological signal, so that the physiological signal measured in the embodiment of the present invention has high accuracy through correction.

In order to make the above features and advantages of the present invention more comprehensible, embodiments are hereinafter described in detail with reference to the accompanying drawings.

FIG. 1 is a block diagram of a physiological signal correction apparatus 100 according to a first embodiment of the present invention. The physiological signal correction device 100 may be a wearable device having a physiological signal correction function. The physiological signal correction device 100 mainly includes a physiological signal sensor 110, a warp sensor 120, and a signal processing device 130. The entire physiological signal correction device 100 can be implemented in the form of a physiological signal sensing patch.

The physiological signal sensor 110 includes one or more sensing electrodes. The physiological signal sensor 110 is attached to the object under test to obtain a physiological signal value from the sensing electrode. The "physiological signal" in this embodiment may be body temperature, pulse, heartbeat, breathing frequency, brain wave signal (EEG), electromyography signal (EMG), nerve electrical signal (ENG), retinal electrical signal (ERG), gastric electrical signal (EGG), neuromuscular signal (ENMG), cerebral cortex signal (ECoG), ocular signal (E0G), nystagmus signal (ENG), etc., depending on the use and requirements of the physiological signal correction device 100 The detection type of the physiological signal by the physiological signal sensor 110. The "physiological signal value" in this embodiment is the value of the physiological signal of the above type. The "object to be tested" in the embodiment of the present invention is mainly the skin of a user (or called, a wearer, such as a person or an animal). The person applying this embodiment can also consider other objects as the object to be tested, as long as the Only the physiological signal value can be sensed on the object. The warp sensor 120 is disposed on the physiological signal sensor 110. The physiological signal sensor 110 and the warp sensor 120 may be made of a plastic material or a flexible material.

The warp sensor 120 is mainly used to detect whether a warp of the physiological signal sensor 110 relative to the object to be measured occurs. The signal processing device 130 is coupled to the physiological signal sensor 110 and the warp sensor 120. The signal processing device 130 corrects the physiological signal value provided by the physiological signal sensor 110 according to the warping situation provided by the warp sensor 120. The physiological signal correction device 100 further includes a transmission module 140, and the transmission module 140 is coupled to the signal processing device 130. The physiological signal correction device 100 may use the transmission module 140 to transmit the detected and corrected physiological signal value to an external information presentation device. As such, in the embodiment, the physiological signal correction device 100 can detect and correct the physiological signal value in real time for transmission to an external information presentation device.

The "warping situation" described in this embodiment is determined by the distance between the sensing electrode on the upper part of the physiological signal sensor 110 and the object to be measured or the contact area between the sensing electrode and the object on the part. Changes occur. For example, the "warping situation" can be composed of two situations. The first situation is that the distance between the sensing electrode on the partial or local physiological signal sensor 110 and the object to be measured is too long, resulting in a physiological signal. The sensor 110 is unable to measure a physiological signal. Such warpage can be represented by the percentage of the area where the physiological signal sensor 110 and the object to be attached and detached from each other are warped. Another situation is that the physiological signal sensor 110 and the object to be measured are indeed closely attached to each other, but some of the sensing electrodes are caused by the deformation and / or wrinkle of the physiological signal sensor 110 due to the deformation of the physiological signal sensor 110 and the object to be measured. The contact area between them is changed and cannot work normally. Such warpage can be expressed by the percentage of the area where the physiological signal sensor 110 and the object to be tested are attached and deformed as the warpage value. For example, the physiological signal sensor 110, which was originally closely attached to the object to be measured, distorts the local physiological signal sensor 110 from the wearer's skin due to sweat or the wearer's movement, and the detected physiological signal is distorted. Or a situation in which the detected physiological signal is distorted because the physiological signal sensor 110 is greatly deformed or wrinkled along with the skin of the wearer. The physiological signal sensor 110 may be provided with one or more kinds of warping sensors 120, so as to more accurately know the warping situation.

In the prior art, the distorted physiological signal detected in the above situation cannot accurately reflect the true physiological state of the wearer, so that the wearable device cannot operate normally. Only after the physiological signal sensor 110 is closely attached to the skin again can the wearable device perform its proper function again. In contrast, in the embodiment of the present invention, the warping sensor 120 is used to obtain the warping value related to the “warping situation”, and the warping value is used to query the correction database located in the physiological signal correction device 100 to generate correction. The physiological signal value after the compensation, thereby compensating or correcting the value generated by the physiological signal sensor 110, and prolonging the time during which the wearable device can function normally in the case of slight warpage.

In the “warping situation” in this embodiment, the percentage of the area attached between the physiological signal sensor 110 and the object to be measured (the skin of the wearer) can be used as the warpage value. In other words, the higher the percentage of the area where the physiological signal sensor 110 is attached to the object to be tested, the lower the degree of the physical signal sensor 110 detaching from the skin, so the physiological signal value that needs to be compensated or corrected The lower it is; the lower the percentage of the area where the physiological signal sensor 110 and the object to be attached to each other are, the higher the degree that the physiological signal sensor 110 is detached from the skin, so the physiological signal value that needs to be compensated or corrected The higher.

In particular, when the physiological signal sensor 110 cannot obtain a physiological signal value or the physiological signal value is lower than a predetermined value, the physiological signal correction device 100 will not use the warping value corresponding to the warping situation to compensate. Or correct the physiological signal value. In contrast, the physiological signal correction device 100 uses other methods to notify the wearer or a person who maintains the physiological signal correction device 100 to warn that the physiological signal correction device 100 has no proper function at this time.

Those applying this embodiment can adjust the corresponding relationship between the physiological signal sensor 110 and the warp sensor 120 according to their needs, and the following examples and illustrations are used for illustration. If distinguished by the detection method of the warp sensor 120, the type of the warp sensor 120 may be a photosensitive sensor (change in photosensitive current), a vibration sensor (a sensor that senses the frequency of vibration on the skin) Change), resistive sensor (change in resistance value on skin surface), capacitive sensor (change in capacitance value on skin surface), microwave sensor (using microwave technology to detect the difference between the sensor and the skin Distance change) or a combination of these sensors. If the warpage sensor 120 is placed at the position of the physiological signal sensor 110 to distinguish, the warpage sensor 120 may be a full-surface type, an area type, or an array type sensor.

FIG. 2A to FIG. 2C are corresponding positions of the physiological signal sensor 110 and the warpage sensor 120. Those applying this embodiment can adjust the corresponding relationship between the physiological signal sensor 110 and the warp sensor 120 according to their needs and the type of implementation of the warp sensor 120. As shown in FIG. 2A, the warp sensor 120 is disposed below the physiological signal sensor 110, and the warp sensor 120 may be a resistive, capacitive, photosensitive, vibration, or radio wave sensor. As shown in FIG. 2B, the warp sensor 120 is configured above the physiological signal sensor 110, and the warp sensor 120 can be implemented by a photosensitive, vibration or radio wave sensor; as shown in FIG. 2B. As shown in FIG. 2C, the physiological signal sensor 110 and the warp sensor 120 are located on the same layer. The warp sensor 120 is disposed around the physiological signal sensor 110, and the warp sensor 120 may be a resistive, Capacitive, photosensitive, vibration or radio wave sensors.

2D to 2E are schematic diagrams of a sensing electrode patch 200 and a test object (skin 210) composed of the warp sensor 120 and the physiological signal sensor 110. The warpage sensor 120 in FIGS. 2D to 2E is a full-surface type, area type, or array type sensor. In other words, in addition to the sensing electrode patch 200 having sensing electrodes for sensing physiological signal values, the entire sensing electrode patch 200 is further provided with a plurality of sensing points 202 of the warpage sensor 120 uniformly distributed. . In FIG. 2D, most areas of the sensing electrode patch 200 and the object to be measured (skin 210) are closely attached, and only a part of the area is warped. The left side of FIG. 2D shows the attachment of the sensing electrode patch 200 and the object to be measured (skin 210), and the area 220 is the warp between the sensing electrode patch 200 and the object to be measured (skin 210). Song situation. FIG. 2D is a schematic diagram showing the distribution of a plurality of sensing points 202 on the sensing electrode patch 200. The local sensing electrode patch 200 in the region 220 cannot detect the physiological signal value because it is not closely attached to the skin 210. In addition, the sensing points 202 located in the area 220 also have different sensing signals compared to other sensing points 202 located outside the area 220 because they do not contact the skin 210. The left side of FIG. 2E shows the attachment of the sensing electrode patch 200 and the object to be measured (skin 210). The sensing electrode patch 200 and the object to be measured (skin 210) are closely adhered to each other and both are severely deformed. Therefore, a part of the sensing points 202 located in the middle of the sensing electrode patch 200 may not be closely attached to the object to be measured (skin 210), which causes the sensing electrode patch 200 and the object to be measured (skin 210) to interact with each other. Detachable warping.

FIG. 3 is a schematic diagram of an implementation of the warpage sensor of the sensing electrode patch 200 in FIG. 2D. The sensing electrode patch 200 in FIG. 3 includes a plurality of sensing points 202 of the warp sensor 120. In this embodiment, a capacitive sensor is used to implement the warpage sensor in the electrode pad 200. That is, each sensing point 202 in this embodiment is implemented by a switch. Each straight switch is connected to a corresponding capacitor C0 ~ CN, where N is a positive integer. When the sensing point 202 realized by the switch is in contact with the object to be measured (skin 210), it is turned on; in contrast, when the sensing point 202 is not in contact with the object to be measured (skin 210), it is turned off. In this way, when the above-mentioned warping occurs (for example, the sensing points 202 in the area 220 are not in contact with the skin 210), the area can be estimated by the total change of the capacitance values in the capacitors C0 ~ CN. 220 is an area percentage of the overall sensing electrode patch 200 as a warpage value. Those applying this embodiment may also use a light sensing element, a resistance element, a vibration element, a microwave element, etc. as the switches of the sensing point 202, so as to implement the warping sensor by various detection methods.

4A and 4B are schematic diagrams of the integrated structure of the physiological signal sensor 110 and the warpage sensor 120. Please refer to FIG. 4A. The warpage sensor 120 and the physiological signal sensor 110 can be integrated on the same substrate 400 through a semiconductor process, and the pins of the warpage sensor 120 and the physiological signal sensor 110 are pulled out. To the corresponding pad 410. Please refer to FIG. 4B, the warp sensor 120 and the physiological signal sensor 110 are respectively manufactured through different semiconductor processes, and the two components are connected by a connection structure 420 (for example, conductive glue, electrodes, screws or a combination thereof). They are connected to each other to integrate the warp sensor 120 and the physiological signal sensor 110 by assembling or pressing.

5A to 5F are corresponding positions of the physiological signal sensor 110, the warpage sensor 120, and the signal processing device 130 in FIG. Those applying this embodiment can integrate the physiological signal sensor 110, the warp sensor 120, and the signal processing device 130 into the physiological signal correction device 100 according to their needs. As shown in FIG. 5A, a warp sensor 120 is disposed above the physiological signal sensor 110, and a signal processing device 130 is disposed beside the physiological signal sensor 110 and the warpage sensor 120. As shown in FIG. 5B, a warp sensor 120 is disposed above the physiological signal sensor 110, and a signal processing device 130 is disposed above the warp sensor 120. As shown in FIG. 5C, a signal processing device 130 is disposed above the physiological signal sensor 110, and a warp sensor 120 is disposed above the signal processing device 130. As shown in FIG. 5D, in addition to the structure of FIG. 5A, the other side of the signal processing device 130 may further be provided with a physiological signal sensor 110 and a warp sensor 120. As shown in FIG. 5E, physiological signal sensors 110 are provided above and below the signal processing device 130, and warpage sensors 120 are provided on both sides or around the signal processing device 130 and the physiological signal sensor 110 to The structure of the physiological signal correction apparatus 100 is similar to that of FIG. 2C. As shown in FIG. 5F, a physiological signal sensor 110 is disposed below the signal processing device 130, and warpage sensors 120 are disposed on both sides or around the signal processing device 130 and the physiological signal sensor 110 to make the physiological signal The structure of the correction device 100 is similar to that of FIG. 2C.

FIG. 6A and FIG. 6B are schematic diagrams of implementing the warp sensor 120 by using a photosensitive sensor. Please refer to FIG. 6A. The left side of FIG. 6A illustrates the physiological signal sensor 110 and the warpage sensor 120. The physiological signal sensor 110 includes a plurality of through holes 610 through which light can pass. The plurality of switches in the warp sensor 120 are implemented by a plurality of photosensitive elements 620A. The photometric surface of the light receiving element 620A is provided facing the through hole 610. Each through hole 610 in this embodiment corresponds to each photosensitive element 620A. The photosensitive element 620A may be a light sensor that generates a corresponding photosensitive current according to the quantity of light. FIG. 6A is a schematic diagram of the sensing electrode patch 200 and the test object (skin 210) composed of the physiological signal sensor 110 and the warpage sensor 120. When the area 630A is warped, the external light will penetrate the through hole 610 from the warped portion, so that the photosensitive element 620A changes from a non-photosensitive state to a photosensitive state to generate a photosensitive current, so that it is known that the sensing electrode patch 200 has a part Warping occurs in a region (eg, region 630A), and the area of the region 630A can be obtained by using the magnitude of the photosensitive current.

Please refer to FIG. 6B. The left side of FIG. 6B also shows the physiological signal sensor 110 and the warpage sensor 120. The main difference between FIG. 6A and FIG. 6B is that each switch of the warpage sensor 120 in FIG. 6B is implemented by a switching unit 620B that combines a light-sensitive element and a light-emitting element (such as a light-emitting diode (LED)). . In other words, the switch in the warp sensor 120 includes a light emitting element corresponding to each light sensing element in addition to the light sensing elements. The photometric surface of the switch unit 620B is provided facing the through hole 610. Each through hole 610 corresponds to each switching unit 620B. Each light-sensitive element and a corresponding light-emitting element are disposed in at least one of a plurality of regions of the warp sensor. In addition, an ambient light sensor 622 is provided on the back of the warp sensor 120.

FIG. 6B is a schematic diagram of the sensing electrode patch 200 and the test object (skin 210) composed of the physiological signal sensor 110 and the warpage sensor 120. Each region in the sensing electrode patch 200 includes a photosensitive element 624 and a light emitting element 626. The light receiving element 624 and the light emitting element 626 constitute a switching unit 620B on the left in FIG. 6B. When the ambient light sensor 622 on the sensing electrode patch 200 is in a photosensitive state due to sufficient external light, the light emitting element 626 will not actively emit light. At this time, external light will penetrate the through hole 610 from the warped portion (area 630B), so that the photosensitive element 624 changes from a non-photosensitive state to a photosensitive state to generate a photosensitive current, so that it is known that the sensing electrode patch 200 has a local Warping occurs in a region (eg, region 630B). In contrast, when the ambient light sensor 622 on the sensing electrode patch 200 is not in a non-photosensitive state due to external light, the light emitting element 626 will actively emit light. At this time, the photosensitive element 624 in the warped area (area 630B) will reduce the amount of light due to the exposure of the light from the light-emitting element 626 (that is, the photosensitive current generated by the photosensitive element 624 is reduced), so as to know the sensing electrode patch. A localized area (eg, area 630B) of 200 is warped. Those applying this embodiment can also replace the photosensitive element 620A in FIG. 6A with a microwave element, a vibration sensor, a resistive sensor, or a capacitive sensor, so as to know whether warping occurs using different detection technologies. And the percentage of the area attached between the physiological signal sensor 110 and the test object (skin 210) as the warpage value.

FIG. 7 is a block diagram of a physiological signal correction device 700, a data presentation device 710, and a cloud server 720 according to a second embodiment of the present invention. The physiological signal correction device 700 includes a physiological signal sensor 110, a warp sensor 120, a signal processing device 730, and a transmission module 140. The transmission module 140 includes a transceiver 740. After obtaining the corrected physiological signal value, the signal processing device 730 of the physiological signal correction device 700 can integrate the corrected physiological signal value by itself, and pass the transceiver 740 through the network 750 or a related transmission protocol ( For example, Bluetooth, WIFI, etc.) transmit these physiological signal values to the information presentation device 710. Alternatively, the physiological signal correction device 700 can directly transmit the corrected physiological signal values to the information presentation device 710 through the transceiver 740, and the information presentation device 710 can automatically integrate these physiological signal values. The information presentation device 710 may be a smart phone, a tablet computer, a personal computer or a server with a screen, etc., and is mainly used to present the physiological signal values of the wearer (for example, body temperature, pulse, heartbeat, respiratory rate, dynamic muscle, etc.). Current value), and the integrated or corrected physiological condition or physiological information (such as wearer's muscle endurance, muscle strength, muscle fatigue, physical condition, exercise cycle, health status, abnormal warning) can be used to present the information 710 is displayed.

Here, the signal processing device 730 and its internal components in the physiological signal correction device 700 of FIG. 7 will be described in detail. The signal processing device 730 includes a processor 732, a compensation circuit 734, and a memory 736. The compensation circuit 734 is coupled to the processor 732. The memory 736 is coupled to the processor 732 and the compensation circuit 734 at the same time. The memory 736 includes a calibration database 738. The correction database 738 includes at least correction signal values corresponding to the warpage data generated by the physiological signal sensor 110 and the warpage sensor 120. The processor 732 in this embodiment can communicate with the cloud server 720 through the transceiver 740 and can update the content in the calibration database 738 from the cloud server 720 to make the correction of the physiological signal value more accurate.

The compensation circuit 734 queries the correction database 738 to obtain the corresponding correction signal value according to the warpage situation provided by the warp sensor 120 (for example, the percentage of the area of attachment between the physiological signal sensor 110 and the object under test) The correction signal value is provided to the processor 732. The processor 732 adds the corrected signal value to the physiological signal value provided by the physiological signal sensor 110 to obtain a corrected physiological signal value. In addition, the processor 732 in the signal processing device 730 may obtain the corrected physiological signal value corresponding to each time point according to multiple time points, and perform data calculation on the corrected physiological signal value corresponding to each time point to obtain multiple Analyze the data, unify the analysis data, and transmit it to the information presentation device 710 through the transceiver. The information presentation device 710 presents these analysis data on its display screen for viewing by the user. The above analysis data can be presented using data chain diagrams or other graphical data. In some embodiments, the above analysis data can also be uploaded to the cloud server 720 for big data analysis and correction of related data.

The table information (Table 1: Contact area between the sensing electrode and the human body; Table 2: Deformation area of the sensing electrode) is used to briefly present the content in the correction database 738 for reference. Those who apply this embodiment More complex database information can be used to show the relationship between the warping value corresponding to the "warping situation" and the correction signal value.

Table 1

The warpage value passed by the warp sensor 120 to the compensation circuit 734 is usually analog information, such as changes in capacitance (capacitive sensors), changes in photosensitive current (photosensitive sensors), changes in resistance (resistance Sensor) and so on. The number of compensation / correction levels can be set according to the actual design of the above analog information. The correction signal value is an encoding value that determines the best digital resolution according to the number of compensation / correction steps. The compensation circuit 734 calculates the area percentage according to the warpage value, and queries Table 1 by using the calculated area percentage to obtain the corresponding correction signal value.

Table 2

Table 2 shows that when the percentage of the deformation area of the physiological signal sensor / sensing electrode is larger, the compensation / correction level is higher, and the correction signal value is increased accordingly.

FIG. 8 is a circuit block diagram of a physiological signal correction apparatus 800 according to a third embodiment of the present invention. This embodiment uses FIG. 8 to explain the detailed circuit structure of the compensation circuit 734. The compensation circuit 734 includes a switcher 810, an analog-to-digital converter 820, a digital signal processor (DSP) 830, and an adder 840. When the sensing electrode patch composed of the warp sensor 120 and the physiological signal sensor 110 is completely attached to the object to be measured, the processor 732 performs an initial operation at time T0 to obtain an initial signal value. The “initial signal value” described in this embodiment may come from a database pre-built on the cloud server 720 of FIG. 7 or a parameter in the calibration database 738 (for example, the user ’s physiological age / height / weight / Blood pressure, ambient temperature / humidity / wind power / wind direction / radiation of ultraviolet rays, etc.) and the calculated compensation value. The application of this embodiment does not limit the source of obtaining the initial signal value. For convenience of explanation, the initial signal value is set to "0110" in this embodiment. In some embodiments, the processor 732 may not need to perform initial operations. At time T1, the processor 732 controls the switcher 810 to obtain a physiological signal value from the physiological signal sensor 110 (for example, the physiological signal value is "0000"). At time T2, the processor 732 controls the switcher 810 to use the warpage value obtained from the warp sensor 120, and uses the analog-to-digital converter 820 and the digital signal processor 830 to digitally encode the warpage value. The warpage value queries the correction database in the memory 736 to obtain the correction signal value. In an embodiment, if there is no correction signal value and an initial signal value, the processor 732 controls the adder 840 to add a physiological signal value ("0000") and an initial signal value ("0110") as a physiological signal. value. In another embodiment, if there is a correction signal value (for example, the correction signal value is "1000") and there is an initial signal value, the processor 732 adds the physiological signal value ("0000") to the initial signal value ( "0110") and then add the correction signal value ("1000") as the corrected physiological signal value. Then, at time T3, the processor 732 transmits the aforementioned physiological signal value or the corrected physiological signal value to the data presentation device through the transceiver 740.

The compensation circuit 734 of FIG. 8 is implemented by a single analog-to-digital converter 820. Those applying this embodiment may also use two analog-to-digital converters 820. One of the analog-to-digital converters is used to integrate the physiological signal sensor 110. The physiological signal value is converted into a digital form. Another analog-to-digital converter is used to convert the warpage value of the warp sensor 120 into a digital form. In this way, the switch of the signal by the switch 810 is not required, and the digital signal processor 830 can process the two data at the same time.

FIG. 9 is a flowchart of a method for calibrating a physiological signal according to an embodiment of the present invention. The correction method is applicable to the physiological signal correction apparatuses 100, 700, and / or 800 of the foregoing embodiments. Referring to FIG. 9, in step S910, when the physiological signal sensor 110 is attached to the object to be measured, the signal processing device in the physiological signal correction device obtains a physiological signal value from the physiological signal sensor 110. In step S920, the signal processing device detects whether the warpage of the physiological signal sensor 110 relative to the object to be tested occurs through the warp sensor 120. The warping situation is caused by the distance between the sensing electrode in the physiological signal sensor 110 and the object to be measured. In step S930, the signal processing device corrects the physiological signal value provided by the physiological signal sensor 110 according to the warping situation provided by the warp sensor 120. For detailed implementation of the foregoing steps, refer to the foregoing embodiments.

In summary, the physiological signal correction device and the wearable device described in the embodiments of the present invention use the warpage sensor disposed on the physiological signal sensor to detect the sensing electrode and the target electrode in the physiological signal sensor. Measure the warpage between objects (such as the user's skin) and correct physiological signals based on the warpage. In other words, in the embodiment of the present invention, one or more warpage sensors are configured on a physiological signal sensor (such as a sensing electrode patch) to detect and feedback the separation between the sensing electrode and the object to be tested. Area percentage value, and use the area percentage value to query the correction database to compensate or correct the missing part of the physiological signal, so that the physiological signal measured in the embodiment of the present invention has high accuracy through correction.

Although the present invention has been disclosed as above with the examples, it is not intended to limit the present invention. Any person with ordinary knowledge in the technical field can make some modifications and retouching without departing from the spirit and scope of the present invention. The protection scope of the present invention shall be determined by the scope of the attached patent application.

100, 700, 800‧‧‧‧ physiological signal correction device

110‧‧‧ physiological signal sensor

120‧‧‧Warp sensor

130, 730‧‧‧ signal processing device

140‧‧‧Transmission Module

200‧‧‧sensing electrode patch

202‧‧‧sensing points

210‧‧‧Skin

220‧‧‧area

400‧‧‧ substrate

410‧‧‧pad

420‧‧‧connection structure

610‧‧‧through hole

620A‧‧‧Photosensitive element

620B‧‧‧Switch unit

622‧‧‧Ambient light sensor

624‧‧‧photosensitive element

626‧‧‧Light-emitting element

630A, 630B‧‧‧area

710‧‧‧ Information Presentation Device

720‧‧‧ Cloud Server

732‧‧‧ processor

734‧‧‧Compensation circuit

736‧‧‧Memory

738‧‧‧ Calibration database

740‧‧‧ Transceiver

750‧‧‧Internet

810‧‧‧Switcher

820‧‧‧ Analog Digital Converter

830‧‧‧ Digital Signal Processor (DSP)

840‧‧‧ Adder

C0 ~ CN‧‧‧Capacitance

FIG. 1 is a block diagram of a physiological signal correction apparatus according to a first embodiment of the present invention. FIG. 2A to FIG. 2C are corresponding positions of the physiological signal sensor and the warpage sensor. 2D to 2E are schematic diagrams of a sensing electrode patch and a test object composed of a warp sensor and a physiological signal sensor. FIG. 3 is a schematic diagram of an implementation of the warpage sensor of the sensing electrode patch in FIG. 2D. 4A and 4B are schematic diagrams of an integrated structure of a physiological signal sensor and a warpage sensor. 5A to 5F are corresponding positions of the physiological signal sensor, the warpage sensor, and the signal processing device in FIG. 1. FIG. 6A and FIG. 6B are schematic diagrams of implementing a warping sensor by using a photosensitive sensor. FIG. 7 is a block diagram of a physiological signal correction device, a data presentation device, and a cloud server according to a second embodiment of the present invention. FIG. 8 is a circuit block diagram of a physiological signal correction apparatus according to a third embodiment of the present invention. FIG. 9 is a flowchart of a method for calibrating a physiological signal according to an embodiment of the present invention.

Claims (20)

A physiological signal correction device includes: a physiological signal sensor having a sensing electrode, the physiological signal sensor is attached to an object to be measured to obtain a physiological signal value from the sensing electrode; a warping sensor, And disposed on the physiological signal sensor, the warpage sensor detects whether a warping condition of the physiological signal sensor relative to the object to be measured occurs; and a signal processing device coupled to the physiological signal sensor. A signal sensor and the warp sensor, wherein the signal processing device corrects the physiological signal provided by the physiological signal sensor according to the warping situation provided by the warp sensor Value, wherein the warping condition is changed by a distance between a part of the sensing electrode and the object to be measured or a contact area between a part of the sensing electrode and the object to be measured Instead. The physiological signal correction device according to item 1 of the scope of the patent application, wherein the warpage is determined by the percentage of the area where the physiological signal sensor and the object to be attached to and detached from each other are used as the warpage value. To indicate, or the warping situation is represented by the percentage of the area where the physiological signal sensor and the object to be tested are attached and deformed as the warpage value. The physiological signal correction device according to item 1 of the scope of patent application, wherein the signal processing device includes: a processor; a compensation circuit coupled to the processor; and a memory including a correction database, wherein the compensation The circuit queries the correction database to obtain a correction signal value according to the warpage situation provided by the warp sensor, and provides the correction signal value to the processor, and the processor provides the correction The signal value is added to the physiological signal value provided by the physiological signal sensor to obtain a corrected physiological signal value. The physiological signal correction device according to item 3 of the patent application scope further includes: a transmission module coupled to the signal processing device, wherein a transceiver of the transmission module and an information presentation device communicate with each other, wherein the signal The processing device integrates the corrected physiological signal value and transmits it to the information presentation device, and the information presentation device presents physiological information corresponding to the object to be tested according to the corrected physiological signal value. The physiological signal correction device according to item 4 of the scope of patent application, wherein the signal processing device removes the physiological signal sensor and the warpage sensor from the test object when the physiological signal sensor and the warp sensor are completely attached to the object to be tested. An initial signal value is obtained in a calibration database or a cloud server, and after obtaining the initial signal value, the physiological signal value is obtained from the sensing electrode of the physiological signal sensor and the warpage sensor is obtained. Obtaining a warping value corresponding to the warping situation, and when obtaining the warping value, the signal processing device queries the correction database according to the warping value to obtain the correction signal value, and The physiological signal value is added with the initial signal value and the corrected signal value as the corrected physiological signal value. The physiological signal correction device according to item 5 of the scope of patent application, wherein the signal processing device obtains the corrected physiological signal value corresponding to each time point according to a plurality of time points, and corresponds to each of the time points. The corrected physiological signal value is subjected to data calculation to obtain a plurality of analysis data, and the analysis data is integrated and transmitted to the information presentation device through the transceiver. The physiological signal correction device according to item 1 of the patent application scope, wherein the physiological signal sensor includes a plurality of through holes, and the warp sensor is provided corresponding to the through holes. The physiological signal correction device according to item 1 of the scope of the patent application, wherein the type of the warpage sensor is a photosensitive sensor, a vibration sensor, a resistance sensor, a capacitive sensor, Microwave sensor or a combination thereof. The physiological signal correction device according to item 8 of the scope of patent application, wherein when the warp sensor is the photosensitive sensor, the warp sensor includes a plurality of photosensitive elements, and Whether or not the warping occurs is determined by whether or not a part of the photosensitive element senses light. The physiological signal correction device according to item 9 of the scope of patent application, wherein the warp sensor further includes a light emitting element corresponding to each of the light sensing elements, and each of the light sensing elements is corresponding to the corresponding light sensing element. The light emitting element is disposed in at least one of a plurality of regions of the warp sensor. A physiological signal correction method is applicable to a physiological signal correction device including a physiological signal sensor and a warp sensor. The warp sensor is disposed on the physiological signal sensor, wherein the correction method includes : When the physiological signal sensor is attached to the object to be measured, obtaining a physiological signal value from the physiological signal sensor; detecting whether the relative occurrence of the physiological signal sensor is detected by the warpage sensor The warping situation of the object to be measured is determined by a distance between a part of the physiological signal sensor and the object to be measured or a portion of the sensing electrode and the object being measured. The contact area between the objects to be tested is changed and generated; and the physiological signal value provided by the physiological signal sensor is corrected according to the warping situation provided by the warpage sensor. The correction method according to item 11 of the scope of patent application, wherein the warpage is represented by the percentage of the area where the physiological signal sensor and the object to be attached and detached from each other are warped. Or, the warping situation is represented by the percentage of area where the physiological signal sensor and the object to be tested are attached and deformed as the warpage value. According to the correction method according to item 11 of the scope of patent application, correcting the physiological signal value provided by the physiological signal sensor according to the warping situation provided by the warp sensor includes the following steps: The corrected signal value is added to the physiological signal value provided by the physiological signal sensor to obtain a corrected physiological signal value. The calibration method according to item 13 of the scope of patent application, further comprising the following steps: When the physiological signal sensor and the warpage sensor are completely attached to the object to be tested, from the calibration database or Obtaining an initial signal value in a cloud server, and correcting the physiological signal value provided by the physiological signal sensor according to the warping situation provided by the warping sensor includes the following steps: After the initial signal value is obtained, obtaining the physiological signal value from the physiological signal sensor and obtaining a warping value corresponding to the warping situation from the warping sensor; and when the warping value is obtained When querying the correction database according to the warpage value to obtain the correction signal value, and adding the physiological signal value and the initial signal value and the correction signal value as the corrected physiological signal value. The correction method according to item 11 of the scope of patent application, further comprising the following steps: obtaining the corrected physiological signal value corresponding to each time point according to multiple time points; the corrected physiological signal value corresponding to each time point The signal value is subjected to data calculation to obtain a plurality of analysis data; and the analysis data is integrated and transmitted to the information presentation device. A wearable device with correction function includes: a physiological signal sensor with a sensing electrode, the physiological signal sensor is attached to an object to be measured to obtain a physiological signal value from the sensing electrode; A sensor configured on the physiological signal sensor, the warpage sensor detecting whether a warping situation of the physiological signal sensor relative to the object to be measured occurs; and a signal processing device coupled to the signal processing device The physiological signal sensor and the warpage sensor, wherein the signal processing device corrects the physiological signal sensor provided by the physiological signal sensor according to the warping situation provided by the warpage sensor. The physiological signal value, wherein the warpage is determined by a distance between a part of the sensing electrode and the object to be tested or a part of the sensing electrode and the object to be measured The contact area is changed. The wearable device according to item 16 of the scope of patent application, wherein the warpage is determined by using the percentage of the area where the physiological signal sensor and the object to be attached and detached from each other as the warpage value. Indicates, or the warping situation is represented by the percentage of the area where the physiological signal sensor and the object to be tested are attached and deformed as the warpage value. The wearable device according to item 16 of the scope of patent application, wherein the signal processing device comprises: a processor; a compensation circuit coupled to the processor; and a memory including a calibration database, wherein the compensation circuit Querying the correction database to obtain a correction signal value according to the warpage situation provided by the warp sensor, and providing the correction signal value to the processor, and the processor providing the correction signal The value is added to the physiological signal value provided by the physiological signal sensor to obtain a corrected physiological signal value. The wearable device according to item 18 of the scope of patent application, further comprising: a transmission module coupled to the signal processing device, wherein a transceiver of the transmission module and an information presentation device communicate with each other, wherein the signal processing The device integrates the corrected physiological signal value and transmits it to the information presentation device, and the information presentation device presents physiological information corresponding to the object to be tested according to the corrected physiological signal value. The wearable device according to item 19 of the scope of patent application, wherein the signal processing device is from the calibration database or a cloud server when the physiological signal sensor is completely attached to the object to be measured. Obtaining an initial signal value, obtaining the physiological signal value from the sensing electrode after obtaining the initial signal value, and obtaining a warping value corresponding to the warping situation from the warping sensor, when obtaining the When the warpage value is described, the signal processing device queries the correction database to obtain the correction signal value according to the warpage value, and adds the physiological signal value to the initial signal value and the correction signal value. As the corrected physiological signal value.