TW201706007A - Detector for scanning ion beam measurement in radiotherapy capable of obtaining a highly precise space resolution, a highly precise space dosage and a highly precise scanning speed by the arrangement of first and second ion chambers and the allocation of first - Google Patents
Detector for scanning ion beam measurement in radiotherapy capable of obtaining a highly precise space resolution, a highly precise space dosage and a highly precise scanning speed by the arrangement of first and second ion chambers and the allocation of first Download PDFInfo
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Abstract
Description
本發明為有關一種偵測器,尤指一種用於放射治療中掃描式離子束量測的偵測器。The invention relates to a detector, in particular to a detector for scanning ion beam measurement in radiation therapy.
癌症又名為惡性腫瘤,其為細胞不正常的增生,且增生的細胞會侵犯身體的其他部分,目前已經成為人類的主要死因之一,癌症可以經手術切除、化療、放射線治療、免疫治療、單株抗體治療或其他方法治療。其中,放射治療最常作為直接或輔助治療癌症的方式,其是使用輻射線殺死癌細胞、縮小腫瘤,藉由輻射線破壞細胞的遺傳物質,可阻止細胞生長或分裂,進而控制癌細胞的生長。Cancer is also known as a malignant tumor, which is an abnormal proliferation of cells, and the proliferating cells will invade other parts of the body. It has become one of the main causes of death in humans. The cancer can be surgically removed, chemotherapy, radiation therapy, immunotherapy, Single antibody treatment or other methods of treatment. Among them, radiation therapy is most often used as a direct or auxiliary treatment for cancer. It uses radiation to kill cancer cells, shrink tumors, and destroy the genetic material of cells by radiation. It can prevent cells from growing or dividing, thereby controlling cancer cells. Growing.
目前常見的放射治療裝置如中華民國專利公告第I489974號之「射程移位器及粒子束治療裝置」,該粒子束治療裝置包含有一產生粒子束的加速器、複數個治療室、複數個照射裝置以及複數個設置於該些照射裝置內的射程移位器,該粒子束由該加速器射入該些治療室,該些照射裝置係分別設於該些治療室,並將該粒子束照射在一照射對象的一照射區上,該射程移位器包含有一穿透板以及一維持該穿透板的保持部,藉由調整該穿透板的厚度,可以使該粒子束具有不同的衰減量,因此,可以對該粒子束的能量進行調整。A conventional radiation therapy device, such as the "range shifter and particle beam therapy device" of the Republic of China Patent Publication No. I489974, the particle beam therapy device includes an accelerator for generating a particle beam, a plurality of treatment rooms, and a plurality of illumination devices. a plurality of range shifters disposed in the illumination devices, the particle beams being incident on the treatment chambers by the accelerators, the illumination devices being respectively disposed in the treatment rooms, and irradiating the particle beam with an illumination On a illuminating area of the object, the range shifter includes a penetrating plate and a holding portion for maintaining the penetrating plate. By adjusting the thickness of the penetrating plate, the particle beam can have different attenuation amounts. The energy of the particle beam can be adjusted.
一般於使用時,還會搭配一偵測器來確認粒子束的參數及輻射劑量遞送的正確性。傳統的治療方式是使用大面積的輻射照射,再根據腫瘤大小製造特定的屏蔽來限制照射的範圍。所以一般使用為二維偵測器或小尺寸偵測器(單通道)做特定位置量測。發明的離子治療方式是使用小尺寸離子束來掃描腫瘤位置,掃描速度可達20 m/sec,控制掃描速度即可控制劑量。但習知的偵測器因空間解析度太大以及量測速度不夠快,而無法對掃描式離子束進行準確的量測,因此,如何提高空間解析度及量測速度,以準確的量測掃描式離子束的參數及輻射劑量,實為一重要的課題。Generally used in conjunction with a detector to confirm the parameters of the particle beam and the correct delivery of radiation dose. The traditional treatment is to use a large area of radiation, and then to create a specific shield according to the size of the tumor to limit the scope of the irradiation. Therefore, it is generally used for a specific position measurement for a two-dimensional detector or a small-sized detector (single channel). The ion treatment method of the invention uses a small-sized ion beam to scan the tumor position at a scanning speed of up to 20 m/sec, and the scanning speed can be controlled to control the dose. However, the conventional detectors cannot measure the scanning ion beam accurately because the spatial resolution is too large and the measurement speed is not fast enough. Therefore, how to improve the spatial resolution and measurement speed to accurately measure The parameters of the scanning ion beam and the radiation dose are an important issue.
本發明的主要目的,在於解決習知偵測器因空間解析度太大以及量測速度不夠快,而無法對掃描式離子束進行準確的量測的問題。The main object of the present invention is to solve the problem that the conventional detector cannot accurately measure the scanning ion beam because the spatial resolution is too large and the measurement speed is not fast enough.
為達上述目的,本發明提供一種用於放射治療中掃描式離子束量測的偵測器,包含有一第一高壓電極、一第二高壓電極、一設置於該第一高壓電極與該第二高壓電極之間的雙面分段電極、一設置於該第一高壓電極與該雙面分段電極之間的第一間隔件以及一設置於該第二高壓電極與該雙面分段電極之間的第二間隔件,該第一高壓電極包含有一第一高壓區以及一圍繞該第一高壓區的第一接地區,該第二高壓電極包含有一第二高壓區以及一圍繞該第二高壓區的第二接地區,該雙面分段電極包含有一與該第一高壓區對應設置的第一偵測區、一背設於該第一偵測區並與該第二高壓區對應設置的第二偵測區、一圍繞該第一偵測區與該第二偵測區的第三接地區、一設置於該第一偵測區的第一讀出電極以及一設置於該第二偵測區的第二讀出電極,該第一間隔件包含有一連接於該第一接地區與該第三接地區的第一框架本體,以及一由該第一框架本體圍繞該第一高壓區、該第一偵測區而成的第一離子腔室,且該第一讀出電極容置於該第一離子腔室內,該第二間隔件包含有一連接於該第二接地區與該第三接地區的第二框架本體,以及一由該第二框架本體圍繞該第二高壓區、該第二偵測區而成的第二離子腔室,且該第二讀出電極容置於該第二離子腔室內。In order to achieve the above object, the present invention provides a detector for scanning ion beam measurement in radiotherapy, comprising a first high voltage electrode, a second high voltage electrode, a first high voltage electrode and the second a double-sided segment electrode between the high voltage electrodes, a first spacer disposed between the first high voltage electrode and the double-sided segment electrode, and a second high voltage electrode and the double-sided segment electrode a second spacer, the first high voltage electrode includes a first high voltage region and a first region surrounding the first high voltage region, the second high voltage electrode includes a second high voltage region and a second high voltage region a second area of the area, the double-sided segment electrode includes a first detection area corresponding to the first high-voltage area, and a second detection area corresponding to the first detection area and corresponding to the second high-voltage area a second detection area, a third connection area surrounding the first detection area and the second detection area, a first readout electrode disposed in the first detection area, and a second detection a second readout electrode of the measurement zone, the first spacer comprising a first frame body connected to the first connection region and the third connection region, and a first ion chamber formed by the first frame body surrounding the first high voltage region and the first detection region, And the first readout electrode is received in the first ion chamber, the second spacer comprises a second frame body connected to the second joint region and the third joint region, and a second frame The second ion chamber is formed by the body surrounding the second high voltage region and the second detecting region, and the second readout electrode is received in the second ion chamber.
綜上所述,本發明藉由設置該第一離子腔室與該第二離子腔室,並搭配設置該第一讀出電極與該第二讀出電極,以增進本發明的空間解析度以及提高本發明的量測速度,因此,可以得到高準確的空間解析度、空間劑量及掃描速度。In summary, the present invention enhances the spatial resolution of the present invention by providing the first ion chamber and the second ion chamber in combination with the first readout electrode and the second readout electrode. The measurement speed of the present invention is improved, and therefore, highly accurate spatial resolution, spatial dose, and scanning speed can be obtained.
有關本發明的詳細說明及技術內容,現就配合圖式說明如下:The detailed description and technical content of the present invention will now be described as follows:
請參閱「圖1A」、「圖1B」及「圖2」所示,為本發明第一實施例的立體結構示意圖、「圖1A」之1B-1B的剖面結構示意圖以及結構分解示意圖。本發明為一種用於放射治療中掃描式粒子束量測的偵測器,包含有一第一高壓電極10、一第一間隔件40、一雙面分段電極30、一第二間隔件50以及一第二高壓電極20,該第一高壓電極10包含有一第一高壓區11以及一圍繞該第一高壓區11的第一接地區12,該第二高壓電極20包含有一第二高壓區21以及一圍繞該第二高壓區21的第二接地區22,該雙面分段電極30設置於該第一高壓電極10與該第二高壓電極20之間,並包含有一與該第一高壓區11對應設置的第一偵測區31、一背設於該第一偵測區31並與該第二高壓區21對應設置的第二偵測區32、一圍繞該第一偵測區31與該第二偵測區32的第三接地區33、一設置於該第一偵測區31的第一讀出電極34以及一設置於該第二偵測區32的第二讀出電極35,該第一間隔件40設置於該第一高壓電極10與該雙面分段電極30之間,包含有一連接於該第一接地區12與該第三接地區33的第一框架本體41,以及一由該第一框架本體41圍繞該第一高壓區11、該第一偵測區31而成的第一離子腔室42,且該第一讀出電極34容置於該第一離子腔室42內,該第二間隔件50設置於該第二高壓電極20與該雙面分段電極30之間的,包含有一連接於該第二接地區22與該第三接地區33的第二框架本體51,以及一由該第二框架本體51圍繞該第二高壓區21、該第二偵測區32而成的第二離子腔室52,且該第二讀出電極35容置於該第二離子腔室52內。Please refer to FIG. 1A, FIG. 1B and FIG. 2 for a schematic perspective view of a first embodiment of the present invention, and a cross-sectional structural view and a structural exploded view of 1B-1B of FIG. 1A. The invention relates to a detector for scanning particle beam measurement in radiotherapy, comprising a first high voltage electrode 10, a first spacer 40, a double-sided segment electrode 30, a second spacer 50 and a second high voltage electrode 20 including a first high voltage region 11 and a first junction region 12 surrounding the first high voltage region 11, the second high voltage electrode 20 including a second high voltage region 21 and a second junction region 22 surrounding the second high voltage region 21, the double-sided segment electrode 30 is disposed between the first high voltage electrode 10 and the second high voltage electrode 20, and includes a first high voltage region 11 Correspondingly disposed, a first detecting area 31, a second detecting area 32 disposed opposite to the first detecting area 31 and corresponding to the second high voltage area 21, and a surrounding the first detecting area 31 and the a third connection region 33 of the second detection region 32, a first readout electrode 34 disposed on the first detection region 31, and a second readout electrode 35 disposed on the second detection region 32. The first spacer 40 is disposed between the first high voltage electrode 10 and the double-sided segment electrode 30, and includes a connection a first frame body 41 connecting the region 12 and the third connection region 33, and a first ion chamber 42 formed by the first frame body 41 surrounding the first high voltage region 11 and the first detection region 31 The first readout electrode 34 is disposed in the first ion chamber 42. The second spacer 50 is disposed between the second high voltage electrode 20 and the double-sided segmented electrode 30, and includes a connection. a second frame body 51 of the second connection area 22 and the third connection area 33, and a second frame formed by the second frame body 51 surrounding the second high voltage area 21 and the second detection area 32. The ion chamber 52 is disposed, and the second readout electrode 35 is received in the second ion chamber 52.
由於本發明具有該第一離子腔室42與該第二離子腔室52,可用於測量X與Y兩個方向的粒子束,且於本實施例中,該第一讀出電極34包含複數條縱向電極341,該第二讀出電極35包含複數條橫向電極351,而該些縱向電極341、該些橫向電極351各為127條,且彼此之間的間距為2毫米(mm),如此一來,本發明可以藉由離子束形狀的量測達到小於0.2毫米(mm)的空間位置解析度,可準確量測粒子束的位置與軌跡,而本發明的量測速度則可以大於10kHz,因此,可以精準地確認粒子束的參數的時間變化或輻射劑量,而提高量測的精準度。Since the present invention has the first ion chamber 42 and the second ion chamber 52, it can be used to measure particle beams in both X and Y directions, and in the embodiment, the first readout electrode 34 includes a plurality of strips. The longitudinal electrode 341, the second readout electrode 35 includes a plurality of lateral electrodes 351, and the longitudinal electrodes 341 and the lateral electrodes 351 are each 127, and the spacing between them is 2 millimeters (mm), such a In the present invention, the spatial position resolution of less than 0.2 millimeters (mm) can be achieved by measuring the shape of the ion beam, and the position and trajectory of the particle beam can be accurately measured, and the measuring speed of the present invention can be greater than 10 kHz. It can accurately confirm the time variation of the particle beam parameters or the radiation dose, and improve the accuracy of the measurement.
此外,該第一間隔件40更包含有一設置於該第一框架本體41的第一透氣部43,該第二間隔件50亦包含有一設置於該第一框架本體41的第二透氣部53,該第一透氣部43使該第一離子腔室42與外部連通,該第二透氣部53使該第二離子腔室52與外部連通,因此,外部的空氣可經由該第一透氣部43與該第二透氣部53進入該第一離子腔室42與該第二離子腔室52內。於此實施例中,該第一間隔件40與該第二間隔件50各有一個,並相互對稱設置,但並不以此為限,而該第一間隔件40與該第二間隔件50的厚度為3毫米(mm),亦可隨使用者的需求而進行調整。In addition, the first spacer 40 further includes a first venting portion 43 disposed on the first frame body 41. The second spacer 50 also includes a second venting portion 53 disposed on the first frame body 41. The first gas permeable portion 43 communicates the first ion chamber 42 with the outside, and the second gas permeable portion 53 connects the second ion chamber 52 with the outside, so that external air can pass through the first gas permeable portion 43 The second gas permeable portion 53 enters the first ion chamber 42 and the second ion chamber 52. In this embodiment, the first spacer 40 and the second spacer 50 are each disposed symmetrically, but not limited thereto, and the first spacer 40 and the second spacer 50 are not limited thereto. The thickness is 3 mm (mm) and can be adjusted according to the needs of the user.
再者,為了使該第一高壓電極10、該第一間隔件40、該雙面分段電極30、該第二間隔件50以及該第二高壓電極20可以穩固接合,更可以於該第一高壓電極10遠離該雙面分段電極30之一側設置一第一固定件60,以及於該第二高壓電極20遠離該雙面分段電極30之一側設置一第二固定件70,於此實施例中,該第一固定件60與該第二固定件70可以利用鎖固的方式來穩固接合,但不以此為限。Furthermore, in order to make the first high voltage electrode 10, the first spacer 40, the double-sided segment electrode 30, the second spacer 50 and the second high voltage electrode 20 can be firmly joined, the first A first fixing member 60 is disposed on a side of the high-voltage electrode 10 away from the double-sided segment electrode 30, and a second fixing member 70 is disposed on a side of the second high-voltage electrode 20 away from the double-sided segment electrode 30. In this embodiment, the first fixing member 60 and the second fixing member 70 can be firmly engaged by using a locking manner, but not limited thereto.
而本發明的操作方式為將該雙面分段電極30與該第一高壓電極10、該第二高壓電極20施加一電壓差,形成一電場,而待測的粒子束進入該第一離子腔室42(X方向)及該第二離子腔室52(Y方向),而使該第一離子腔室42與該第二離子腔室52內的氣體離子化,再經由該電場的作用,使離子聚集至該雙面分段電極30的該第一偵測區31與該第二偵測區32上,而該第一讀出電極34與該第二讀出電極35則用以收集聚集於該第一偵測區31與該第二偵測區32上的離子,以進行後續之分析。The operation mode of the present invention is to apply a voltage difference between the double-sided segment electrode 30 and the first high voltage electrode 10 and the second high voltage electrode 20 to form an electric field, and the particle beam to be tested enters the first ion cavity. The chamber 42 (X direction) and the second ion chamber 52 (Y direction) ionize the gas in the first ion chamber 42 and the second ion chamber 52, and then through the action of the electric field The ions are collected on the first detection area 31 and the second detection area 32 of the double-sided segment electrode 30, and the first readout electrode 34 and the second readout electrode 35 are used to collect and collect The ions on the first detection area 31 and the second detection area 32 are subjected to subsequent analysis.
綜上所述,由於設置兩個離子腔室,並搭配雙面縱橫向電極,可以提高本發明的空間解析度以及增進本發明的量測速度,因此,可得到高準確的空間解析度、空間劑量及掃描速度。In summary, since two ion chambers are provided and the double-sided vertical and horizontal electrodes are provided, the spatial resolution of the present invention can be improved and the measurement speed of the present invention can be improved. Therefore, a highly accurate spatial resolution and space can be obtained. Dose and scanning speed.
因此本發明極具進步性及符合申請發明專利的要件,爰依法提出申請,祈鈞局早日賜准專利,實感德便。Therefore, the present invention is highly progressive and conforms to the requirements of the invention patent application, and the application is made according to law, and the praying office grants the patent as soon as possible.
以上已將本發明做一詳細說明,惟以上所述者,僅爲本發明的一較佳實施例而已,當不能限定本發明實施的範圍。即凡依本發明申請範圍所作的均等變化與修飾等,皆應仍屬本發明的專利涵蓋範圍內。The present invention has been described in detail above, but the foregoing is only a preferred embodiment of the present invention, and is not intended to limit the scope of the invention. That is, the equivalent changes and modifications made by the scope of the present application should remain within the scope of the patent of the present invention.
10‧‧‧第一高壓電極
11‧‧‧第一高壓區
12‧‧‧第一接地區
20‧‧‧第二高壓電極
21‧‧‧第二高壓區
22‧‧‧第二接地區
30‧‧‧雙面分段電極
31‧‧‧第一偵測區
32‧‧‧第二偵測區
33‧‧‧第三接地區
34‧‧‧第一讀出電極
341‧‧‧縱向電極
35‧‧‧第二讀出電極
351‧‧‧橫向電極
40‧‧‧第一間隔件
41‧‧‧第一框架本體
42‧‧‧第一離子腔室
43‧‧‧第一透氣部
50‧‧‧第二間隔件
51‧‧‧第二框架本體
52‧‧‧第二離子腔室
53‧‧‧第二透氣部
60‧‧‧第一固定件
70‧‧‧第二固定件10‧‧‧First high voltage electrode
11‧‧‧First High Pressure Zone
12‧‧‧ First access area
20‧‧‧second high voltage electrode
21‧‧‧Second high pressure zone
22‧‧‧second area
30‧‧‧Double-section electrode
31‧‧‧First detection area
32‧‧‧Second detection area
33‧‧‧ Third access area
34‧‧‧First readout electrode
341‧‧‧ longitudinal electrode
35‧‧‧Second readout electrode
351‧‧‧Transverse electrode
40‧‧‧First spacer
41‧‧‧First framework ontology
42‧‧‧First Ion Chamber
43‧‧‧First Ventilation Department
50‧‧‧Second spacer
51‧‧‧Second framework ontology
52‧‧‧Second ion chamber
53‧‧‧Second breathable part
60‧‧‧First fixture
70‧‧‧Second fixture
圖1A,為本發明第一實施例的立體結構示意圖。 圖1B,為本發明「圖1A」之1B-1B的剖面結構示意圖。 圖2,為本發明第一實施例的結構分解示意圖。FIG. 1A is a schematic perspective view of a first embodiment of the present invention. Fig. 1B is a schematic cross-sectional view showing the structure of 1B-1B of Fig. 1A of the present invention. Fig. 2 is a schematic exploded view showing the structure of the first embodiment of the present invention.
10‧‧‧第一高壓電極 10‧‧‧First high voltage electrode
11‧‧‧第一高壓區 11‧‧‧First High Pressure Zone
12‧‧‧第一接地區 12‧‧‧ First access area
20‧‧‧第二高壓電極 20‧‧‧second high voltage electrode
21‧‧‧第二高壓區 21‧‧‧Second high pressure zone
22‧‧‧第二接地區 22‧‧‧second area
30‧‧‧雙面分段電極 30‧‧‧Double-section electrode
31‧‧‧第一偵測區 31‧‧‧First detection area
33‧‧‧第三接地區 33‧‧‧ Third access area
34‧‧‧第一讀出電極 34‧‧‧First readout electrode
341‧‧‧縱向電極 341‧‧‧ longitudinal electrode
35‧‧‧第二讀出電極 35‧‧‧Second readout electrode
351‧‧‧橫向電極 351‧‧‧Transverse electrode
40‧‧‧第一間隔件 40‧‧‧First spacer
41‧‧‧第一框架本體 41‧‧‧First framework ontology
43‧‧‧第一透氣部 43‧‧‧First Ventilation Department
50‧‧‧第二間隔件 50‧‧‧Second spacer
51‧‧‧第二框架本體 51‧‧‧Second framework ontology
53‧‧‧第二透氣部 53‧‧‧Second breathable part
60‧‧‧第一固定件 60‧‧‧First fixture
70‧‧‧第二固定件 70‧‧‧Second fixture
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