TW201643201A - Cross-linked product of carboxymethyl group-containing modified hyaluronic acid and/or salt of same, and method for producing same - Google Patents

Cross-linked product of carboxymethyl group-containing modified hyaluronic acid and/or salt of same, and method for producing same

Info

Publication number
TW201643201A
TW201643201A TW105111329A TW105111329A TW201643201A TW 201643201 A TW201643201 A TW 201643201A TW 105111329 A TW105111329 A TW 105111329A TW 105111329 A TW105111329 A TW 105111329A TW 201643201 A TW201643201 A TW 201643201A
Authority
TW
Taiwan
Prior art keywords
same
salt
hyaluronic acid
modified hyaluronic
carboxymethyl group
Prior art date
Application number
TW105111329A
Other languages
Chinese (zh)
Inventor
Nakamae Ryota
fujikawa Shunichi
Yoshida Hideto
Original Assignee
Kewpie Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kewpie Corp filed Critical Kewpie Corp
Publication of TW201643201A publication Critical patent/TW201643201A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses

Abstract

Provided is a method for producing a cross-linked product of carboxymethyl group-containing modified hyaluronic acid and/or a salt of the same, having excellent thermal stability, enzymolysis resistance and water-swelling characteristics. The method for producing a cross-linked product of carboxymethyl group-containing modified hyaluronic acid and/or a salt of the same uses a condensing agent to crosslink a carboxymethyl group-containing modified hyaluronic acid and/or a salt of the same by ester bonding between hydroxyl groups and carboxyl groups on the modified hyaluronic acid and/or the salt of the same.
TW105111329A 2015-04-15 2016-04-12 Cross-linked product of carboxymethyl group-containing modified hyaluronic acid and/or salt of same, and method for producing same TW201643201A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015082143 2015-04-15

Publications (1)

Publication Number Publication Date
TW201643201A true TW201643201A (en) 2016-12-16

Family

ID=57126851

Family Applications (1)

Application Number Title Priority Date Filing Date
TW105111329A TW201643201A (en) 2015-04-15 2016-04-12 Cross-linked product of carboxymethyl group-containing modified hyaluronic acid and/or salt of same, and method for producing same

Country Status (3)

Country Link
JP (1) JP6046869B1 (en)
TW (1) TW201643201A (en)
WO (1) WO2016167229A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109890847A (en) * 2016-10-31 2019-06-14 丘比株式会社 Gel combination and its manufacturing method
JP2019019201A (en) * 2017-07-14 2019-02-07 キユーピー株式会社 Crosslinked hyaluronic acid and manufacturing method therefor
CN112147029A (en) * 2019-06-28 2020-12-29 杭州协合医疗用品有限公司 Method for measuring swelling degree of cross-linked sodium hyaluronate gel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5690961A (en) * 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses
JP4958368B2 (en) * 2002-02-28 2012-06-20 電気化学工業株式会社 Cross-linked hyaluronic acid
WO2005056608A1 (en) * 2003-12-04 2005-06-23 University Of Utah Research Foundation Modified macromolecules and methods of making and using thereof
CN101225125B (en) * 2008-01-18 2012-12-05 中国科学院烟台海岸带研究所 Moisture absorption humectant and method for preparing same
EP2609924A4 (en) * 2010-08-23 2014-01-22 Denki Kagaku Kogyo Kk Crosslinked hyaluronic acid composition and self-crosslinking hyaluronic acid particles

Also Published As

Publication number Publication date
JP6046869B1 (en) 2016-12-21
JPWO2016167229A1 (en) 2017-04-27
WO2016167229A1 (en) 2016-10-20

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