TW201632211A - Volumetric oriented, real-time and dynamic automatic dialysis water removing system - Google Patents

Abstract

A volumetric oriented, real-time and dynamic automatic dialysis water removing system is disclosed, which comprises a hemodialysis unit. The hemodialysis unit comprises a calculation module and a hemodialysis module. The calculation module is utilized to receive a weight signal and convert the weight signal into a speed signal. The hemodialysis module comprising a water removing speed regulator is utilized to receive the speed signal of the calculation module. The disclosed is able to adjust based on the weight of a user' internal water content the speed by using the water removing speed regulator of the hemodialysis module, and also increase gradually the water removal speed. Therefore, the disclosed is able to solve the hypotension problem caused by the constant hemodialysis speed in conventional skills.

Description

Volume-oriented and instant dynamic automatic dialysis moisture removal system

The present invention relates to a moisture removal system, and more particularly to a moisture removal system that can adjust the hemodialysis rate instantaneously and automatically depending on the volume of moisture.

Prior art hemodialyzers remove moisture from the user's body at a fixed rate of moisture removal, which is calculated as Equation A, which is Where W is the total weight of water to be removed by dialysis (kg) and T is the total dialysis time (hours). However, kidney users or users of diabetes who are undergoing hemodialysis are often prone to complications of hypotension during hemodialysis. The causes of hypotension include: excessive removal of water during dialysis and abnormal autonomic function. Peripheral blood vessel blood pressure is lowered, and the user is poorly tolerated by dialysate, resulting in vasodilation or a decrease in oxygen content in the blood. Therefore, after hemodialysis, the user is often uncomfortable, and the user often needs to rest for at least half a day to recover the physical strength. Therefore, the prior art fixed blood removal rate hemodialyzer is extremely great for the user's daily life quality. influences.

In view of the deficiencies of the prior art, it is an object of the present invention to provide a volume-directed and instantaneous dynamic automatic dialysis moisture removal system that regulates hemodialysis rates based on the volume of water in the body of the user.

To achieve the above object, the volume-directed and instantaneous dynamic automatic dialysis moisture removal system provided by the present invention comprises a hemodialysis unit comprising a calculation module and a hemodialysis module. The computing module receives a weight signal and converts the weight signal into a moisture removal rate signal according to at least two formulas. The hemodialysis module has a moisture removal rate adjuster, and the hemodialysis module is connected to the computing module and receives the rate signal from the computing module, and then transmits the rate signal to the moisture removal rate adjuster. The rate of moisture removal is regulated by a moisture removal rate adjuster that exhibits an increasing trend as hemodialysis time increases.

Preferably, the computing module divides the total dialysis time into N time phases, which are sequentially the first time phase, the second time phase... to the Nth time phase, where N≧2, The calculation module has two formulas of formula I and formula II. Equation I corresponds to the first time phase, and Equation I is: ; Formula II corresponds to the rest of the time phase, which is: . Wherein V ₁ is the moisture removal rate of the first time phase; V _n is the moisture removal rate of the nth time phase, wherein N≧n≧2; W is the total weight of the removed moisture (kg); W _{n- 1} is the weight of water removed in the n-1th time period, where N≧n≧2; T is the total dialysis time (hours); T _n-1 is the total time spent until the n-1th time period, Where N≧n≧2.

Preferably, the volume-oriented and instantaneous dynamic automatic dialysis moisture removal system further comprises an integrated temperature detecting unit, the body temperature detecting unit is adjacent to the hemodialysis unit, and the body temperature detecting unit receives the integrated temperature signal.

Preferably, the volume-directed and instantaneous dynamic automatic dialysis moisture removal system further comprises a blood temperature adjustment unit adjacent to the hemodialysis unit, and the blood temperature adjustment unit adjusts the blood dialysis unit. The temperature of the blood of the user after dialysis prevents the temperature of the blood of the user from being in contact with the body temperature of the user during hemodialysis, resulting in a discomfort caused by the user's blood pressure change during dialysis.

Preferably, the blood temperature adjustment unit adjusts the blood temperature to between 34oC and 37oC.

Preferably, the volume-directed and instantaneous dynamic automatic dialysis moisture removal system further comprises a blood flow rate adjusting unit adjacent to the hemodialysis unit, and the blood flow rate adjusting unit adjusts the flow rate of the blood.

Preferably, the blood flow rate adjusting unit has a blood flow rate of 100 ml per minute for the remaining 10 minutes to 20 minutes of the total dialysis time of the hemodialysis, so as to reduce the pressure generated by the blood flow rate and the pressure generated by the hemodialysis. The pressure difference between the users avoids the discomfort caused by the pressure difference after the dialysis is completed.

According to the present invention, the user does not accumulate water before hemodialysis, has no extremity edema and pulmonary edema, and has normal blood pressure before hemodialysis, or the body weight when blood pressure is not too low after hemodialysis is defined as dry weight. When the user performs hemodialysis using the volume-directed and dynamic dynamic automatic dialysis water removal system of the present invention, the total weight of moisture removed is based on no more than 8% of the dry weight of the user.

The computing module according to the present invention calculates a rate signal by receiving a weight signal; the rate signal is transmitted to the hemodialysis module, and the rate signal is transmitted to the moisture removal rate adjuster through the hemodialysis module. The moisture removal rate regulator regulates the rate of moisture dialysis. Accordingly, the present invention provides for the use of a lower initial moisture removal rate and based on the volume of moisture in the user's body to adjust and sequentially increase the moisture removal of the volume-directed and instantaneous dynamic automatic dialysis moisture removal system of the present invention. The rate is used to solve the problem in the prior art that the user uses the constant hemodialysis rate to cause hypotension during hemodialysis. In addition, the volume-directed and instantaneous dynamic automatic dialysis moisture removal system needle of the present invention is suitable for users who are 3% to 8% of the total weight of water to be removed by dialysis.

The following examples are intended to illustrate the invention. The examples are not intended to limit the scope of the invention in any way, but are intended to indicate how to practice the materials and methods of the invention.

Referring to FIG. 1 , the present invention provides a volume-directed and instantaneous dynamic automatic dialysis water removal system 1 including a hemodialysis unit 10 including a calculation module 11 and a hemodialysis module. 12.

The computing module 11 receives a weight signal and converts the weight signal into a moisture removal rate signal according to at least two formulas. The hemodialysis module 12 has a moisture removal rate adjuster 121, and the hemodialysis module 12 is connected to the computing module 11 and receives the rate signal from the computing module 11, and then transmits the rate signal to the moisture shift. In addition to the rate adjuster 121, the rate of moisture removal by the moisture removal rate adjuster 121 is regulated.

In a preferred embodiment, the volume-directed and dynamic dynamic automatic dialysis water removal system 1 further includes an integrated temperature detecting unit 20 adjacent to the hemodialysis unit 10 and a body temperature detecting unit. The 20 Series receives the integrated temperature signal.

In another preferred embodiment, the volume-directed and instantaneous dynamic automatic dialysis moisture removal system 1 further includes a blood temperature adjustment unit 30 adjacent to the hemodialysis unit 10 and having a blood temperature The conditioning unit 30 adjusts the temperature of the blood of the user after dialysis by the hemodialysis unit 10, which adjusts the blood temperature to between 34oC and 37oC via the hemodialysis unit 10.

In another preferred embodiment, the volume-directed and instantaneous dynamic automatic dialysis moisture removal system 1 further includes a blood flow rate adjustment unit 40 that regulates the flow rate of blood, and the blood flow rate adjustment unit 40 Adjacent to the hemodialysis unit 10; when the total dialysis time of hemodialysis remains 10 minutes, the blood flow rate is reduced to 100 ml per minute by the blood flow rate adjusting unit 40.

Example 1 : In a first preferred embodiment, the weight signal is measured by a scale or scale connected to a volume-directed and instantaneous dynamic automatic dialysis moisture removal system. In a first preferred embodiment, the computing module divides the total dialysis time into N time phases, which are sequentially the first time phase, the second time phase... to the Nth time phase, where N≧2 The calculation module has two formulas of Formula I and Formula II. Equation I corresponds to the first time phase, which is as follows: Equation II corresponds to the rest of the time phase, which is as follows: Wherein V ₁ is the moisture removal rate of the first time phase; V _n is the moisture removal rate of the nth time phase, wherein N≧n≧2; W is the total weight of the removed moisture (kg); W _{n -1} is the weight of water removed in the n-1th time period, where N≧n≧2; T is the total dialysis time (hours); T _n-1 is the total time spent until the n-1th time period , where N≧n≧2.

Example 2 : The effect of the volume-oriented and instant dynamic automatic dialysis water removal system of the present invention for regulating blood pressure

Experimental group 1: When the user performs hemodialysis, the rate signal is calculated according to the formula I and the formula II described in the first preferred embodiment. As shown in Table 1, the user has a body weight of 59.2 kg and diastolic before performing hemodialysis. The pressure is 82 mm Hg and the systolic blood pressure is 138 mm Hg. After 270 minutes of hemodialysis, the body weight is 57.5 kg, the diastolic blood pressure drops from 82 mm Hg to 81 mm Hg, and the systolic blood pressure drops from 138 mm Hg. Up to 129 mm Hg. Table 1 Time, weight and blood pressure changes during hemodialysis

The results in Table 1 show that after hemodialysis by the volume-guided and dynamic dynamic automatic dialysis water removal system of the present invention, the blood pressure of the user before hemodialysis and after hemodialysis slightly decreased, but did not decrease to 110 mm. Uncomfortable under the mercury column.

Experimental group 2: When the user performs hemodialysis, the rate signal is calculated according to the formula I and the formula II described in the first preferred embodiment. As shown in Table 2, the user has a body weight of 60.6 kg and diastolic before performing hemodialysis. The pressure was 78 mm Hg and the systolic pressure was 129 mm Hg. After 180 minutes of hemodialysis, the body weight was 57.3 kg, the diastolic blood pressure was increased from 78 mm Hg to 88 mm Hg, and the systolic blood pressure was increased from 129 mm Hg. To 144 mm Hg. Table 2 Changes in time, weight and blood pressure of users undergoing hemodialysis

The results in Table 2 show that after hemodialysis by the volume-directed and dynamic dynamic automatic dialysis water removal system of the present invention, the blood pressure of the user before hemodialysis and after hemodialysis does not decrease, therefore, the user is After the completion of dialysis, there was no discomfort due to a decrease in blood pressure.

Comparative Example: Effect of hemodialysis apparatus of prior art on blood dialysis rate for regulating blood pressure

Control group: Before hemodialysis, the user had a body weight of 59.7 kg, a diastolic blood pressure of 76 mm Hg, and a systolic blood pressure of 118 mm Hg. After 260 minutes of isokinetic hemodialysis, the body weight was 57.8 kg and the diastolic blood pressure was 76. The millimeters of mercury dropped to 67 mm Hg and the systolic pressure dropped from 118 mm Hg to 100 mm Hg. Table 3 Changes in time, weight and blood pressure of users during hemodialysis

The results in Table 3 show that after hemodialysis by the prior art hemodialyzer, the user feels uncomfortable after the dialysis is completed because the systolic blood pressure is significantly reduced to below 110 mmHg.

1‧‧‧ Volume-oriented and instant dynamic automatic dialysis moisture removal system
10‧‧‧hemodialysis unit
11‧‧‧Computation Module
12‧‧‧hemodialysis module
121‧‧‧Water Removal Rate Regulator
20‧‧‧ body temperature detection unit
30‧‧‧ Blood temperature adjustment unit
40‧‧‧ Blood flow rate adjustment unit

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 is a schematic illustration of the volume directed and immediate dynamic automatic dialysis moisture removal system of the present invention.

(no)

1‧‧‧ Volume-oriented and instant dynamic automatic dialysis moisture removal system

10‧‧‧hemodialysis unit

11‧‧‧Computation Module

12‧‧‧hemodialysis module

121‧‧‧Water Removal Rate Regulator

20‧‧‧ body temperature detection unit

30‧‧‧ Blood temperature adjustment unit

40‧‧‧ Blood flow rate adjustment unit

Claims (9)

A volume-directed and instantaneous dynamic automatic dialysis water removal system comprising a hemodialysis unit, the hemodialysis unit comprising: a computing module that receives a weight signal and converts the weight signal into a moisture according to at least two formulas a rate signal for removing; and a hemodialysis module having a moisture removal rate adjuster, wherein the hemodialysis module is coupled to the computing module and receives a rate signal from the computing module, and then The rate signal is transmitted to the moisture removal rate adjuster and the rate of moisture removal is regulated by a moisture removal rate adjuster that increases in rate as the hemodialysis time increases. The volume-oriented and instant dynamic automatic dialysis moisture removal system according to claim 1, wherein the calculation module divides the total dialysis time into N time phases, which are sequentially the first time phase and the second time phase. .. to the Nth time phase, where N≧2, the calculation module has two formulas of Formula I and Formula II; The Formula I corresponds to the first time phase, and the Formula I is as follows: Formula II This formula II corresponds to the rest of the time phase, which is as follows: Wherein V ₁ is the moisture removal rate of the first time phase; V _n is the moisture removal rate of the nth time phase, wherein N≧n≧2; W is the total weight of moisture removed (kg); _N-1 is the weight of water removed in the n-1th time period, where N≧n≧2; T is the total dialysis time (hours); T _n-1 is the total cost to the n-1th time period Time, where N≧n≧2. The volume-directed and instantaneous dynamic automatic dialysis moisture removal system of claim 1, wherein the volume-directed and instantaneous dynamic automatic dialysis moisture removal system further comprises an integrated temperature detecting unit, the body temperature detecting unit and the blood The dialysis unit is adjacent, and the body temperature detecting unit receives the integrated temperature signal. The volume-directed and instantaneous dynamic automatic dialysis moisture removal system of any one of claims 1 to 3, wherein the volume-directed and instantaneous dynamic automatic dialysis moisture removal system further comprises a blood temperature adjustment unit, the blood A temperature adjustment unit is adjacent to the hemodialysis unit, and the blood temperature adjustment unit adjusts a temperature of blood after dialysis by the hemodialysis unit. A volume-directed and instantaneous dynamic autodialysis moisture removal system as claimed in claim 4, wherein the blood temperature adjustment unit adjusts the blood temperature to between 34oC and 37oC. The volume-directed and instantaneous dynamic automatic dialysis moisture removal system of any one of claims 1 to 3, wherein the volume-directed and instantaneous dynamic automatic dialysis moisture removal system further comprises a blood flow rate adjustment unit, the blood A flow rate adjustment unit is adjacent to the hemodialysis unit, and the blood flow rate adjustment unit regulates the rate of blood. The volume-directed and instantaneous dynamic automatic dialysis moisture removal system of claim 4, wherein the volume-directed and instantaneous dynamic automatic dialysis water removal system further comprises a blood flow rate adjustment unit, the blood flow rate adjustment unit and the blood The dialysis units are adjacent and the blood flow rate adjustment unit regulates the rate of blood. The volume-directed and instantaneous dynamic automatic dialysis moisture removal system of claim 6, wherein the blood flow rate adjustment unit has a blood flow rate of 100 milliliters per minute remaining between 10 minutes and 20 minutes of the total dialysis time of hemodialysis. The volume-directed and instantaneous dynamic automatic dialysis moisture removal system of claim 7, wherein the blood flow rate adjustment unit has a blood flow rate of 100 milliliters per minute for a remaining 10 minutes to 20 minutes of the total dialysis time of hemodialysis.