TW201613624A - Use of lactobacillus reuteri GMNL-263 for manufacturing composition for increasing expression of LDL-R and CYP7A1 in liver in high-fat diet individual - Google Patents
Use of lactobacillus reuteri GMNL-263 for manufacturing composition for increasing expression of LDL-R and CYP7A1 in liver in high-fat diet individualInfo
- Publication number
- TW201613624A TW201613624A TW103134389A TW103134389A TW201613624A TW 201613624 A TW201613624 A TW 201613624A TW 103134389 A TW103134389 A TW 103134389A TW 103134389 A TW103134389 A TW 103134389A TW 201613624 A TW201613624 A TW 201613624A
- Authority
- TW
- Taiwan
- Prior art keywords
- cyp7a1
- ldl
- liver
- individual
- lactobacillus reuteri
- Prior art date
Links
- 241000186604 Lactobacillus reuteri Species 0.000 title abstract 3
- 229940001882 lactobacillus reuteri Drugs 0.000 title abstract 3
- 102100038637 Cytochrome P450 7A1 Human genes 0.000 title abstract 2
- 101000957672 Homo sapiens Cytochrome P450 7A1 Proteins 0.000 title abstract 2
- 235000009200 high fat diet Nutrition 0.000 title abstract 2
- 210000004185 liver Anatomy 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000008021 deposition Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/173—Reuteri
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW103134389A TWI627959B (zh) | 2014-10-02 | 2014-10-02 | 羅伊氏乳桿菌GMNL-263 用於製備提升高油脂飲食者肝臟低密度脂蛋白受體與膽固醇7α-羥化酶基因表現之組合物之用途 |
US14/618,188 US9895400B2 (en) | 2014-10-02 | 2015-02-10 | Composition and use of Lactobacillus reuteri GMNL-263 in decreasing blood lipid levels |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW103134389A TWI627959B (zh) | 2014-10-02 | 2014-10-02 | 羅伊氏乳桿菌GMNL-263 用於製備提升高油脂飲食者肝臟低密度脂蛋白受體與膽固醇7α-羥化酶基因表現之組合物之用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
TW201613624A true TW201613624A (en) | 2016-04-16 |
TWI627959B TWI627959B (zh) | 2018-07-01 |
Family
ID=55632005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW103134389A TWI627959B (zh) | 2014-10-02 | 2014-10-02 | 羅伊氏乳桿菌GMNL-263 用於製備提升高油脂飲食者肝臟低密度脂蛋白受體與膽固醇7α-羥化酶基因表現之組合物之用途 |
Country Status (2)
Country | Link |
---|---|
US (1) | US9895400B2 (zh) |
TW (1) | TWI627959B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113403231A (zh) * | 2021-07-08 | 2021-09-17 | 江南大学 | 一株可干预代谢综合征的罗伊氏乳杆菌ccfm1178及应用 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20190388484A1 (en) * | 2018-06-26 | 2019-12-26 | Genmont Biotech Incorporation | Lactobacillus reuteri gmnl-263 for improving hypertension and its compositions thereof |
US20220105141A1 (en) * | 2018-06-26 | 2022-04-07 | Genmont Biotech Incorporation | Lactobacillus reuteri gmnl-263 for improving hypertension and its compositions thereof |
CN114391652B (zh) * | 2021-12-09 | 2023-08-22 | 中国农业科学院特产研究所 | 一种具有降血脂和调节肠道菌群结构功能的人参不溶性膳食纤维组合物及其制备方法与应用 |
CN114344344B (zh) * | 2022-01-05 | 2023-06-13 | 东北农业大学 | 罗伊氏乳杆菌在缓解高脂饮食诱导小鼠肥胖功能中的应用及含有罗伊氏乳杆菌的复合物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010048918A1 (en) * | 1996-02-28 | 2001-12-06 | Lourus Cornelis Lievense | Food products containing bacteria with cholesterol lowering activity |
TWI387460B (zh) | 2009-06-24 | 2013-03-01 | Uni President Entpr Corp | 一種具有調降血糖血脂以及脂肪肝的多效複方食品組合及其各素材之抽出方法 |
TWI340021B (en) * | 2010-03-31 | 2011-04-11 | Genmont Biotech Inc | Novel lactobacillus strain, composition and use thereof for improving the syndrome of diabetes and complication thereof |
US8298526B2 (en) * | 2010-06-02 | 2012-10-30 | Genmont Biotech Inc. | Lactobacillus strain, composition and use thereof for improving the syndrome of diabetes and complication thereof |
TWI441643B (zh) | 2010-10-28 | 2014-06-21 | Uni President Biotech Co | 調整血脂及保護心血管之組合物 |
TWI355939B (en) | 2011-01-14 | 2012-01-11 | Genmont Biotech Inc | Composition and use of probiotic strain gm-263 (ad |
US20120183504A1 (en) * | 2011-01-14 | 2012-07-19 | Ying-Chen Lu | Composition and use of probiotic strain gm-263 (adr-1) in treating renal fibrosis in diabetes |
TWI440465B (zh) | 2012-07-04 | 2014-06-11 | Timing Pharmaceutical Co Ltd | 用以降血脂的中草藥萃取混合物及其醫藥組合物 |
-
2014
- 2014-10-02 TW TW103134389A patent/TWI627959B/zh active
-
2015
- 2015-02-10 US US14/618,188 patent/US9895400B2/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113403231A (zh) * | 2021-07-08 | 2021-09-17 | 江南大学 | 一株可干预代谢综合征的罗伊氏乳杆菌ccfm1178及应用 |
Also Published As
Publication number | Publication date |
---|---|
TWI627959B (zh) | 2018-07-01 |
US20160095889A1 (en) | 2016-04-07 |
US9895400B2 (en) | 2018-02-20 |
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