TW201612521A - Reagent and detection method by use of serum fetuin A as biomarkers for detecting hemolytic uremic and necrotizing pneumonia caused and infected by streptococcus pneumoniae - Google Patents
Reagent and detection method by use of serum fetuin A as biomarkers for detecting hemolytic uremic and necrotizing pneumonia caused and infected by streptococcus pneumoniaeInfo
- Publication number
- TW201612521A TW201612521A TW103131847A TW103131847A TW201612521A TW 201612521 A TW201612521 A TW 201612521A TW 103131847 A TW103131847 A TW 103131847A TW 103131847 A TW103131847 A TW 103131847A TW 201612521 A TW201612521 A TW 201612521A
- Authority
- TW
- Taiwan
- Prior art keywords
- streptococcus pneumoniae
- serum
- fetuin
- infected
- reagent
- Prior art date
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Asialoglycoprotein that enriches the serum is called fetuin-A (that is also called [alpha] 2-Heremans-Schmid glycoprotein, or abbreviated as AHSG), which will be an attacked target by neuraminidase of streptococcus pneumoniae caused by severe streptococcus pneumoniae infection, so that the concentration level of fetuin-A of serum is significantly decreased. With the infection of streptococcus pneumoniae, we may qualitatively and quantitatively analyze the results of serum fetuin-A and other asialoglycoproteins, which can differentiate invasive pneumococcal diseases (abbreviated as IPD) from other pneumonia infection symptoms. According to the concentration level of serum fetuin-A, the present invention provides a kind of reagent and method as a basis to evaluate whether the severe invasive pneumococcal diseases are infected and attacked by streptococcus pneumoniae.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW103131847A TWI536017B (en) | 2014-09-16 | 2014-09-16 | Detection of hemolytic uremia by using serum fetuin A as a biomarker to detect streptococcus pneumoniae infection |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW103131847A TWI536017B (en) | 2014-09-16 | 2014-09-16 | Detection of hemolytic uremia by using serum fetuin A as a biomarker to detect streptococcus pneumoniae infection |
Publications (2)
Publication Number | Publication Date |
---|---|
TW201612521A true TW201612521A (en) | 2016-04-01 |
TWI536017B TWI536017B (en) | 2016-06-01 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW103131847A TWI536017B (en) | 2014-09-16 | 2014-09-16 | Detection of hemolytic uremia by using serum fetuin A as a biomarker to detect streptococcus pneumoniae infection |
Country Status (1)
Country | Link |
---|---|
TW (1) | TWI536017B (en) |
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2014
- 2014-09-16 TW TW103131847A patent/TWI536017B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TWI536017B (en) | 2016-06-01 |
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