TW201612183A - Diaryl macrocycles as modulators of protein kinases - Google Patents
Diaryl macrocycles as modulators of protein kinasesInfo
- Publication number
- TW201612183A TW201612183A TW104107098A TW104107098A TW201612183A TW 201612183 A TW201612183 A TW 201612183A TW 104107098 A TW104107098 A TW 104107098A TW 104107098 A TW104107098 A TW 104107098A TW 201612183 A TW201612183 A TW 201612183A
- Authority
- TW
- Taiwan
- Prior art keywords
- modulators
- protein kinases
- macrocycles
- diaryl
- diaryl macrocycles
- Prior art date
Links
Abstract
The present invention relates to certain diaryl macrocyclic compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating cancer, pain, neurological diseases, autoimmune diseases, and inflammation.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462049326P | 2014-09-11 | 2014-09-11 | |
US62/049,326 | 2014-09-11 | ||
US201562106301P | 2015-01-22 | 2015-01-22 | |
US62/106,301 | 2015-01-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
TW201612183A true TW201612183A (en) | 2016-04-01 |
TWI688567B TWI688567B (en) | 2020-03-21 |
Family
ID=56360757
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW109104720A TWI736134B (en) | 2014-09-11 | 2015-03-05 | Diaryl macrocycles as modulators of protein kinases |
TW104107098A TWI688567B (en) | 2014-09-11 | 2015-03-05 | Diaryl macrocycles as modulators of protein kinases |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW109104720A TWI736134B (en) | 2014-09-11 | 2015-03-05 | Diaryl macrocycles as modulators of protein kinases |
Country Status (1)
Country | Link |
---|---|
TW (2) | TWI736134B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111182903A (en) * | 2017-07-28 | 2020-05-19 | 特普医药公司 | Macrocyclic compounds and uses thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8815872B2 (en) * | 2008-09-08 | 2014-08-26 | Merck Patent Gmbh | Macrocyclics pyrimidines as aurora kinase inhibitors |
HUE035337T2 (en) * | 2010-05-20 | 2018-05-02 | Array Biopharma Inc | Macrocyclic compounds as TRK kinase inhibitors |
-
2015
- 2015-03-05 TW TW109104720A patent/TWI736134B/en active
- 2015-03-05 TW TW104107098A patent/TWI688567B/en active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111182903A (en) * | 2017-07-28 | 2020-05-19 | 特普医药公司 | Macrocyclic compounds and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
TWI688567B (en) | 2020-03-21 |
TW202035425A (en) | 2020-10-01 |
TWI736134B (en) | 2021-08-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA202004100B (en) | Diaryl macrocycles as modulators of protein kinases | |
MX2017017097A (en) | Chiral diaryl macrocycles as modulators of protein kinases. | |
PH12020550901A1 (en) | Macrocyclic compounds for treating disease | |
PH12016501139B1 (en) | Bicyclic heterocycle compounds and their uses in therapy | |
MX2019001125A (en) | Macrocycle kinase inhibitors. | |
EA033374B1 (en) | Solid pharmaceutical compositions comprising enzalutamide and method of treatment | |
SG10201810879VA (en) | Pharmaceutical compounds | |
GEP20217317B (en) | Combination therapy for the treatment of cancer | |
PH12019501079A1 (en) | Magl inhibitors | |
PH12016502249A1 (en) | Pladienolide pyridine compounds and methods of use | |
PH12019502363A1 (en) | Phenyl-2-hydroxy-acetylamino-2-methyl-phenyl compounds | |
TW201613935A (en) | Tricyclic heterocycles as BET protein inhibitors | |
AU2018253600A1 (en) | Dosage forms and therapeutic uses of l-4-chlorokynurenine | |
MX2017014456A (en) | Therapeutic uses of l-4-chlorokynurenine. | |
SG10201908881PA (en) | Fused bicyclic compounds for the treatment of disease | |
MX2017009608A (en) | Anti-cancer compounds. | |
IN2013MU03118A (en) | ||
TW201612183A (en) | Diaryl macrocycles as modulators of protein kinases |